83 results about "Blood inflow" patented technology

A prosthetic valve having a stent structure with a prosthetic valve component secured therein is disclosed that includes a device for restricting expansion, i.e., an expansion restrictor device, disposed at a blood inflow end of the stent structure. The expansion restrictor device defines a deployed diameter of the stent structure to prevent the prosthetic valve from being over-sized upon initial deployment and/or from continued expansion in vivo. The expansion restrictor device may be a loop of suture, flexible line, thread or cord for defining or constraining a circumference of the prosthetic valve with a loop diameter that is less than or substantially equal to a diameter of the treatment site in which the prosthetic valve is to be deployed in vivo.

A prosthetic venous valve includes a frame and leaflets. The frame includes: (i) a generally hollow base disposed at a blood inflow end; (ii) a plurality of struts connected with the base and extending generally parallel to a direction of forward flow of blood from the generally hollow base to a blood outflow end; and (iii) inwardly oriented flanges disposed at the blood outflow ends of the struts. The leaflets are disposed in gaps between the struts and are supported by the frame. The leaflets are arranged to close into the vein lumen to substantially seal against backflow of blood from the blood outflow end to the blood inflow end. The inwardly oriented flanges of the struts enhance the sealing.

A method for the integrated facilitization of blood flow and monitoring of blood analyte concentration (for example, blood glucose concentration) includes implanting a stent configured to facilitate blood flow into a cardiovascular system of a user's body with the stent having attached thereto a continuous blood analyte determination module of a blood analyte monitoring system. The method also includes disposing a reader module of the blood analyte monitoring system external to the user's body and in proximity to a portion of the user's skin layer and monitoring blood analyte concentration via (i) emitting an RF carrier signal from the reader module toward the stent; (ii) receiving the RF carrier signal at a reflection antenna of the continuous blood analyte determination module; (iii) reflecting a modulated signal by the reflection antenna with the modulated signal being encoded with a blood analyte concentration determined by a sensor of the continuous blood analyte determination module; (iv) receiving the modulated signal by the reader module; and (v) decoding the analyte concentration from the modulated signal by the reader module.

Apparatus and methods for the extracorporeal treatment of blood are described. The apparatus includes a dialyzer which is separated into a first and second chamber by a semipermeable membrane, wherein the first chamber is disposed in a dialysis fluid path and the second chamber can be connected to the blood circulation of a patient by way of a blood inflow conduit and a blood outflow conduit, a feed for fresh dialysis fluid, a discharge for spent dialysis fluid, a measuring device disposed within the discharge for determining the absorption of the spent dialysis fluid flowing through the discharge, wherein the measuring device has at least one radiation source for substantially monochromatic electromagnetic radiation, and a detector system for detecting the intensity of the electromagnetic radiation, wherein means are provided to compensate for changes that occur in the intensity of the electromagnetic radiation of the radiation source and/or the sensitivity of the detector system.

This invention describes apical access methods and devices that enable repair, modification, removal, and/or replacement of a defective heart valve while allowing the beating heart to deliver blood flow through the defective valve annulus for an extended period of time in volumes sufficient to sustain life. The invention is comprised of a flow housing having a blood inflow opening, a blood outflow opening, and a one-way valve disposed within the flow housing between the inflow and outflow openings.

A method is provided for detecting filter clogging which are able to keep track of the filter clogging with precision and in detail. At least one pressure selected from the group consisting of a pressure Pa in a blood inflow portion (32a), a pressure Pv in a blood outflow portion (32b), a pressure Pf1 in a filtrate inflow portion (32c), and a pressure Pf2 in a filtrate outflow portion (32d) is measured continuously, then a variation (pressure waveform) of the pressure is analyzed, a clogging of a filter (32) is detected using the analyzed result. Thereby a clogging of a filter is detected early. As a result, it is possible to prevent from developing of the filter clogging by controlling a dosage amount of anti-coagulant properly and changing a flow rate of blood. The variation of the pressure wave may be analyzed by subjecting the variable to Fast Fourier Transform.

A replacement heart valve structure including a structure of tissue which is an intact, mammalian heart valve that has been harvested and treated to preserve it. A conventional fabric sleeve is typically disposed concentrically around the outside of the tissue structure. A support structure is included to facilitate implanting the heart valve by somewhat increasing the stability of the heart valve structure, but without unduly rigidifying it. An annular sewing cuff may be added adjacent the blood inflow end of the valve structure to facilitate making the annular suture line that is required at that end.

A system and method for non-invasively estimating an absolute blood flow of a vascular region in a subject using optical data are provided. In some aspects, the method includes acquiring optical datafrom the vascular region using one or more optical sensors placed about the subject, and determining, using the optical data, an index of blood flow and. a blood volume associated with the vascular region. The method also includes computing a blood inflow and a blood outflow using the index of blood flow and the blood volume, and estimating an absolute blood flow using the blood inflow and blood outflow. The method further includes generating a report indicative of the absolute blood flow of the vascular region.

A centrifugal blood pump with stable rotation, which includes a housing and an impeller installed in the housing. The housing is facing the center of the impeller with a positioning shaft matched with the center hole of the impeller; the impeller is installed on the upper cover and the lower cover The center of the spiral blood channel between; the upper cover and the lower cover are respectively provided with a blood inflow tube and a blood outflow tube communicating with the blood channel; the blades in the impeller include the main blade and the auxiliary blade connected to the outer end of the main blade; The main blades are evenly arranged along the circumference of the rotor, and the included angle between the main blades and the rotational flow direction of blood in the blood channel is an obtuse angle. The invention optimizes the design of the impeller and related structural design, so that the centrifugal blood pump has higher pumping efficiency at low speed, ensures blood arterial pressure, reduces wear at low speed, prolongs the life of the blood pump, and also reduces energy consumption. Low power consumption improves the battery life of the blood pump, and the low speed also reduces the difficulty of blood pump working pressure control, making it easier to use and operate.

The extracorporeal blood circulating apparatus of the present invention includes: a closed-type venous reservoir having a blood storage chamber and a volume adjusting chamber that are disposed adjacently by partitioning a closed space formed by a housing; an adjusting liquid tank for storing an adjusting liquid that is connected to the volume adjusting chamber; and a blood pump that is connected to the blood storage chamber. In the housing, an inflow port for allowing blood to inflow and an outflow port for allowing blood to outflow are provided so as to communicate with the blood storage chamber, and an adjusting port for injecting and ejecting the adjusting liquid is provided so as to communicate with the volume adjusting chamber. The blood pump is connected via the outflow port, and the adjusting liquid tank is connected via the adjusting port. The closed space is partitioned by a flexible septum member so as to form the blood storage chamber and the volume adjusting chamber, and the adjusting liquid tank and the adjusting port are connected by a conduit member having a configuration that can adjust a flowing amount. Control of a blood storage amount to be most appropriate and easy adjustment are possible throughout all steps from before starting an extracorporeal blood circulation to terminating it.

The invention relates to a device for the citrate anti-coagulated extracorporeal blood purification comprising:

• an extracorporeal blood purification system comprising an extracorporeal blood circuit (202), which comprises a dialysis unit (205), a blood inflow (203) and a blood discharge (204), a citrate metering device (212) for supplying citrate at a citrate supply point (213) upstream of the dialysis unit (205), a substitution medium metering device (214) for supplying a substitution medium at a substitution medium supply point (215) downstream from the dialysis unit (205), at least one ion concentration measuring means (224) for measuring bivalent cations and a controller (225), wherein the controller (225) is adapted to regulate the metering of the substitution medium as a function of a comparison between a setpoint value range and the ion concentration measured by means of the ion concentration measuring means (224), wherein the ion concentration measuring means (224) is adapted for the continuous generation of measuring values and is arranged upstream of the citrate supply point (213) and the controller (225) is adapted to continuously carry out a regulation of the metering of the citrate and of the substitution medium in consideration of a target value or target value range, which can be predetermined in the controller (225) downstream from the citrate supply point (213). The invention further relates to a method for detecting the ion concentration.

A surgical apparatus for treating a blood clot in a vessel of a patient having an elongated member having an outer wall, a first hole at a distal portion and a second hole spaced proximally from the first hole positioned in a side wall. A first lumen is provided within the elongated member for blood flow through the second hole, through the lumen and exiting the first hole to maintain blood flow during treatment of the blood clot. An energy emitter emits energy to the blood clot or hardenings and a connector connects the energy emitter to an external energy source, wherein blood flows into the second hole positioned proximal of the blood clot and exits the first hole distal of the blood clot during activation of the energy emitter. In some instances when the apparatus is introduced from a retrograde ‘upstream” approach blood may flow through the device in the opposite direction.

This artificial lung includes: a housing; a hollow fiber membrane layer that is housed inside the housing and in which a multitude of hollow fiber membranes having a gas exchange function are integrated; a gas inflow section and a gas outflow section that employ the lumen of each hollow fiber membrane as a gas flow path and that are provided respectively on the upstream side and the downstream side of the gas flow paths; a blood inflow section and a blood outflow section that employ the outside of the hollow fiber membranes as a blood flow path and that are provided respectively on the upstream side and the downstream side of the blood flow path; a first filter member that is provided in contact with the surface of the hollow fiber membrane layer on the side of the blood outflow section and covers almost the entire surface, the first filter member having the function of capturing bubbles in the blood; and a second filter member spaced away from the first filter member and arranged between the first filter member and the blood outflow section, the second filter member having the function of capturing bubbles in the blood.

A cardiotomy reservoir, comprising an outer wall provided, at the lid, with connectors for the inflow of blood to be filtered and, at the bottom, with a connector for the outflow of the filtered blood, a filtering mass being provided which divides the space delimited by the outer wall into a portion that is connected to the inflow connectors and a portion that is connected to the outflow connector; the cardiotomy reservoir comprises a layer of material adapted to retain fats present in blood, and further comprises a first partition and a second partition, which are adapted to delimit at different distances the region that comprises the blood outflow connector and are provided with ports for the passage of the blood in its path for accessing the connector which are arranged at differentiated levels with respect to the bottom, the ports that are provided in the first partition that lies closest to the outflow connector being located at a height, from the bottom, that is greater than the height of the ports provided in the second partition, detachable elements for blocking the blood outflow connector being further provided.

The invention provides an extracorporeal membrane lung oxygenator which comprises a main shell, a first end and a second end cover, the first end and the second end cover are arranged at the two ends of the main shell, the main shell comprises a center cavity for blood to flow in, a temperature control cavity and a gas exchange cavity, and the temperature control cavity and the gas exchange cavity spirally surround the center cavity; an annular space is formed among the temperature control cavity, the gas exchange cavity and the inner wall of the main shell; the first end cover is provided with a blood inflow runner communicated with the central cavity, and a temperature control medium outflow runner and an oxygenation medium outflow runner which spirally surround the blood inflow runner; the second end cover is provided with a blood outflow flow channel communicated with the annular space, and a temperature control medium inflow flow channel and an oxygenation medium inflow flow channel which spirally surround the blood inflow flow channel; the flowing sectional area of the temperature control medium flowing-in flow channel is gradually reduced; and the flowing sectional area of the oxygenation medium flowing-in flow channel is gradually reduced. The pressure of the oxygen-enriched gas and the pressure of the temperature control medium can be evenly distributed, and the optimal heat and gas exchange efficiency is achieved.

A surgical apparatus for treating a vessel blockage in a vessel of a patient having an elongated member having an outer wall, a first hole at a distal portion and a second hole spaced proximally from the first hole positioned in a side wall. A first lumen is provided within the elongated member for blood flow through the second hole, through the lumen and exiting the first hole to maintain blood flow during treatment of the vessel blockage. A motor driven impeller is rotatable during blood flow through the first lumen to enhance blood flow as blood flows into the second hole positioned proximal of the vessel blockage and exits the first hole distal of the vessel blockage during injection of fluid through one or more openings to treat the vessel blockage.

The invention relates to a heart valve prosthesis device for replacing a damaged heart valve caused by congenital or acquired reasons and provides a wide-inlet large-flow heart valve prosthesis. The existing defects are overcome by increasing the inlet area. The heart valve prosthesis comprises a valve and a valve ring and is characterized in that the section area of an inflow port of the valve ring is larger than that of an outflow port. Compared with a common valve, the novel valve is structurally characterized in that a blood inflow face of the valve ring of the valve is a streamlined horn mouth, the inlet area is increased, under the same condition, compared with the common valve, outlet flow is larger, and haemodynamics performance of the valve is improved.