11 results about "Beating heart" patented technology

Disclosed herein are minimally invasive systems and methods for performing an edge to edge repair of a heart valve on a beating heart of a patient. One or more sutures are inserted into a plurality of leaflets of the heart valve while the heart is beating through a minimally invasive access. The sutures can be threaded through a suture crimp that is advanced to the leaflets. A movable gate on the suture crimp can be actuated to secure the sutures at an appropriate tension to maintain the leaflets in a coapted position.

Disclosed is a computer-implemented method for non-invasive estimation of Pulmonary Hypertension, PH, from heart sound signals. Consistent with the disclosure, the method includes the steps of: receiving a sound signal acquired from a beating heart of a subject over a predetermined time period; generating one or more 2D feature maps comprising a 2D feature map with the received sound signal where a first axis of the map is arranged over time and a second axis of the map is arranged over individual heartbeats; applying a pre-trained neural network to relate the generated one or more 2D feature maps with a training dataset of previously acquired and generated training 2D feature maps of a PH subject group and a non-PH subject group, thus to obtain an indicator of the presence of Pulmonary Hypertension. Also disclosed is a training method of said neural network and a system.

Apparatus and methods for deriving and displaying a time-averaged fetal heart rate signal in combination with microvariability information relating to beat-to-beat heart rate signal variability within different time-averaged epochs or windows. Supplementary information is displayed, for example, in temporal alignment or registration with the time-averaged heart rate signal, which indicates signal variability information during the averaging window of the time-averaged signal.

A device is for detecting magnetic signals produced by a beating heart. The device includes at least one nitrogen vacancy center, NV, a magnetometer unit, configured to sense a magnetic field strength and / or field direction, at least one further sensor, and a signal processing unit, to which the at least one NV magnetometer unit and the at least one further sensor are connected. The device is configured to, using the signal processing unit, determine at least one effective magnetic field strength and / or at least one effective field direction from the signals of the at least one NV magnetometer unit and the at least one further

The present application relates to the technical field of physiological signal processing, and discloses an energy consumption estimation method and device based on electrocardiosignal and a storage medium. The method extracts beat-by-beat heart beat information, heart rate variability features and electrocardio-derived respiration features from an ECG signal, and combines signal quality control, metabolic intensity regression model and start-stop kinetics compensation to realize continuous estimation of instantaneous energy consumption rate and cumulative energy consumption.

An implantable medical device includes an activity sensor, a pulse generator, and a control module. The control module is configured to determine activity metrics from the activity signal and determine an activity metric value at a predetermined percentile of the activity metrics. The control module sets a lower pacing rate set point based on the activity metric value at the predetermined percentile.

An access device for a heart chamber, a removable hemostatic valve unit, and a system and a method of creating a transapical passage on a beating heart are disclosed. In examples, the access device (1) includes an apical base plate (100) and a sealing unit (3) configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

The application relates to the technical field of cell differentiation and the technical field of myocardial tissue regeneration medicine, in particular to an induced culture medium and method for quickly obtaining a spontaneously beating myocardial ball, wherein the myocardial cells of a human induced pluripotent stem cell (hiPSC) source obtained through co-culture with hMSCs are combined with a differentiation culture medium, so that the myocardial cell clones harvested on day 7 are more independent and naturally separated from other non-myocardial cells, the myocardial clones can be quickly screened and purified through physical and non-enzyme reagents, the step of medium screening and purification in the traditional method is omitted, and time and differentiation cost are saved.

A synthetic patient specific A benchtop beating heart simulator that is custom-fabricated using 3D printing technology based on patient-specific imaging data has been developed. The simulator employs soft robotics to accurately mimic the motion and biomechanics of the left atrium, with a particular focus on the left atrial appendage and conditions associated with Heart failure with preserved ejection fraction (HFpEF). This simulator is designed to recreate hemodynamics in a controlled benchtop setting, allowing for precise testing and evaluation of medical device designs and interventions.