5 results about "Ventricular wall" patented technology

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

This invention discloses a method for predicting sudden cardiac death based on forensic autopsy data using machine learning and its forensic applications, belonging to the fields of machine learning, statistics, and forensic identification. This invention provides a method for screening independent predictors of forensic diagnosis of sudden cardiac death using LASSO regression and logistic regression. Using 10-fold cross-validation, the method selects the minimum lambda(λ) to identify 14 risk factors. Logistic regression ultimately identifies 9 independent predictors, including age, heart weight, left ventricular wall thickness, right ventricular wall thickness, interventricular septum thickness, aortic valve circumference, mitral valve circumference, liver weight, and left kidney weight. A nomogram and a web-based calculator are constructed for predicting sudden cardiac death in forensic practice, thereby determining sudden cardiac death using objective indicators. This method has not been reported worldwide.

The application discloses a ventricular support drainage device, which comprises a drainage tube, a self-expanding support bracket, a delivery tube and a support strip. The self-expanding support bracket is arranged outside the drainage tube, and the support bracket in an expanded state is used for supporting the ventricular wall. A small protrusion is arranged inside the support bracket, and the small protrusion is in close contact with the drainage tube in a compressed state. The delivery tube is sleeved outside the drainage tube and the support bracket, and is used for maintaining the drainage tube and the support bracket in the compressed state. The support strip is arranged inside the drainage tube in the compressed state, and is used for supporting the whole structure during delivery. The support strip is used for delivering the drainage tube and the support bracket compressed in the delivery tube to a drainage position under the support of the support strip, and maintaining the position of the drainage tube unchanged when the delivery tube is withdrawn. The support strip is blocked at the first end of the drainage tube. The arrangement guarantees that the drainage device is effectively delivered, and the support bracket plays a supporting role and the drainage tube plays a drainage role after being delivered.

The present invention belongs to the technical field of biology, and particularly relates to a compound for treating myocardial infarction. A chondroitin sulfate oligosaccharide in the present invention is extracted from natural chondroitin sulfate. After the chondroitin sulfate oligosaccharide is treated by a chemically enzymatic process into an oligosaccharide chain, experiments prove that the chondroitin sulfate oligosaccharide contributes to the survival of cardiomyocytes. Compared with other products with similar functions, a glycopeptide polymer hydrogel formed after the introduction of a polymer backbone overcomes the problem of batch-to-batch differences of natural products and has a definite structure. Moreover, the hydrogel has excellent inherent biological activity, and does not need to load active ingredients such as other drugs. The hydrogel exhibits an obvious effect on supporting the ventricular wall in an infarcted area and promoting the survival of cardiomyocytes, and can effectively limit the area of myocardial infarction, increase the ventricular wall thickness of the infarcted area, and alleviate cardiac damage caused by myocardial infarction, and therefore has a good application prospect.

The present invention relates to a medical device for anchoring a heart pump in an opening in a ventricular wall of a heart, comprising a connector (10) intended to be mounted on said ventricular wall.According to the invention, - this connector (10) comprises an assembly flange (11) and a support skirt (12), extending from this assembly flange (11), this support skirt (12) being intended to be placed outside the heart when the assembly flange (11) is assembled to the ventricular wall, this connector (10) defining a first opening for the passage of a part of the body of an insert (14), - this insert (14) being entirely rigid and defining a second opening for the passage of the body of the cardiac pump, this insert (14) comprising a distal end intended to be placed inside the heart and a proximal end intended to be placed outside the heart when this insert (14) is mounted on the connector (10), and - at least one locking / unlocking element (19) in the position of the insert (14) relative to the connector (10), when this insert (14) has been introduced into the connector (10). [Fig. 1].