20 results about "Ventricular wall" patented technology

The invention relates to a flexible lockable rope-driven mechanical arm system for cardiac resection, which belongs to the technical field of minimally invasive interventional surgical instruments and comprises a flexible mechanical arm component, an end effector component, a near-end connecting seat and a locking component. The flexible mechanical arm assembly is formed by connecting a plurality of guiding discs and a plurality of locking pieces in series, the guiding discs are arranged at intervals, one locking piece is arranged every multiple guiding discs, and the guiding discs are connected with a driving rope in series through a length restraining rod. The near-end connecting base is used for being connected with a catheter sheathing canal or a mechanical arm driving base and providing an inlet for the length restraining rod and the multiple driving ropes. The end effector assembly is used for cardiac muscle resection; according to the flexible mechanical arm assembly, complex three-dimensional path planning in a narrow cardiac cavity and posture locking under a target posture can be achieved, and the positioning precision and posture stability in the myocardial resection process are improved. The end effector assembly includes a telescopic knife and a protective depth limiting structure that reduces the risk of penetrating the ventricular wall and damaging adjacent valves and conduction bundles.

The invention discloses a myocardial stress determination method, device and equipment based on cardiac ultrasound and a medium, and relates to the field of myocardial stress evaluation.The method adopts a double-mapping network mode and comprises the steps that a cardiac medical image is acquired and labeled, and a feature database of the cardiac bimodal image in the systolic period and the diastolic period is constructed; constructing a first mapping network and performing training, and then performing segmentation and three-dimensional reconstruction on a to-be-processed cardiac ultrasound image to obtain a double-ventricle three-dimensional model; obtaining a finite element simulation model of the double ventricles and carrying out finite element simulation calculation to obtain a ventricle wall stress-strain simulation result; constructing a heart model-simulation result pairing database; constructing a second mapping network; training the second mapping network based on the heart model-simulation result pairing database; and determining a myocardial stress result based on the trained second mapping network. According to the method, the current situation that the myocardial stress cannot be effectively measured and evaluated by a traditional cardiac ultrasound method is effectively improved.

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

This invention discloses a method for predicting sudden cardiac death based on forensic autopsy data using machine learning and its forensic applications, belonging to the fields of machine learning, statistics, and forensic identification. This invention provides a method for screening independent predictors of forensic diagnosis of sudden cardiac death using LASSO regression and logistic regression. Using 10-fold cross-validation, the method selects the minimum lambda(λ) to identify 14 risk factors. Logistic regression ultimately identifies 9 independent predictors, including age, heart weight, left ventricular wall thickness, right ventricular wall thickness, interventricular septum thickness, aortic valve circumference, mitral valve circumference, liver weight, and left kidney weight. A nomogram and a web-based calculator are constructed for predicting sudden cardiac death in forensic practice, thereby determining sudden cardiac death using objective indicators. This method has not been reported worldwide.

The application relates to a method and device for estimating a ventricular wall motion based on an adaptive regularization optical flow model, belonging to the technical field of ultrasonic image processing. The method is characterized in that: firstly, the obtained optical flow vector is analyzed through two-dimensional wavelet analysis and function mapping to obtain motion boundary information of the motion field relative to sudden change; secondly, the sudden change motion boundary information is adaptively fed back to the optical flow calculation model to correct the regularization coefficient of the smoothing term and recalculate the optical flow field; finally, the optical flow calculation process is repeated until the wavelet high-frequency component of the optical flow field converges; the method reflects the gradient difference between the myocardial ventricular wall and the surrounding tissue in the regularization coefficient, thereby improving the accuracy of motion estimation.

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chorda.

The present invention provides a method and apparatus for transvascular implantation of newly formed chordae tendineae. [Solution] A method and apparatus for transvascular implantation of artificial chordae tendineae are disclosed. A catheter advances through the mitral valve into the left atrium and left ventricle. A ventricular anchor is deployed from the catheter into the wall of the left ventricle, extending proximal through the catheter, leaving a ventricular suture attached to the anchor. A leaflet anchor is deployed with the leaflet suture extending proximal through the catheter to fix the mitral valve leaflet to the leaflet suture. The leaflet suture is fixed to the ventricular suture to limit the range of movement of the leaflet toward the left atrium. Also disclosed is a mitral valve leaflet restraint assembly that is assembled in its original location, having neopapillary muscle and neochordae tendineae.

The invention relates to a ventricular assist system. The ventricular assist system comprises a ventricular assist device, a docking device and a locking device. The ventricular auxiliary device comprises a pump body which is provided with a booster cavity; the butt joint device comprises a pipe assembly and a connecting assembly, the pipe assembly is provided with a liquid flow channel, and the pipe assembly is detachably connected with the pump body so that the liquid flow channel can communicate with the booster cavity; the connecting assembly is connected with the tube assembly, the connecting assembly can be connected with the heart, and when the connecting assembly is connected to the heart, the tube assembly penetrates through the ventricular wall; a locking device is capable of removably connecting the tube assembly to the pump body. According to the ventricular auxiliary system, the ventricular auxiliary device can be conveniently replaced or disassembled by operating the locking device, the tube assembly does not need to be withdrawn from the heart, the defect that when an existing blood pump is replaced, the whole blood pump needs to be withdrawn from the heart, consequently, the tube assembly is separated from newly-growing tissue is overcome, harm to a patient is reduced, and the blood pump replacement efficiency is improved. And the pipe assembly can be reused, and the cost is saved.

The application discloses a ventricular support drainage device, which comprises a drainage tube, a self-expanding support bracket, a delivery tube and a support strip. The self-expanding support bracket is arranged outside the drainage tube, and the support bracket in an expanded state is used for supporting the ventricular wall. A small protrusion is arranged inside the support bracket, and the small protrusion is in close contact with the drainage tube in a compressed state. The delivery tube is sleeved outside the drainage tube and the support bracket, and is used for maintaining the drainage tube and the support bracket in the compressed state. The support strip is arranged inside the drainage tube in the compressed state, and is used for supporting the whole structure during delivery. The support strip is used for delivering the drainage tube and the support bracket compressed in the delivery tube to a drainage position under the support of the support strip, and maintaining the position of the drainage tube unchanged when the delivery tube is withdrawn. The support strip is blocked at the first end of the drainage tube. The arrangement guarantees that the drainage device is effectively delivered, and the support bracket plays a supporting role and the drainage tube plays a drainage role after being delivered.

The present invention belongs to the technical field of biology, and particularly relates to a compound for treating myocardial infarction. A chondroitin sulfate oligosaccharide in the present invention is extracted from natural chondroitin sulfate. After the chondroitin sulfate oligosaccharide is treated by a chemically enzymatic process into an oligosaccharide chain, experiments prove that the chondroitin sulfate oligosaccharide contributes to the survival of cardiomyocytes. Compared with other products with similar functions, a glycopeptide polymer hydrogel formed after the introduction of a polymer backbone overcomes the problem of batch-to-batch differences of natural products and has a definite structure. Moreover, the hydrogel has excellent inherent biological activity, and does not need to load active ingredients such as other drugs. The hydrogel exhibits an obvious effect on supporting the ventricular wall in an infarcted area and promoting the survival of cardiomyocytes, and can effectively limit the area of myocardial infarction, increase the ventricular wall thickness of the infarcted area, and alleviate cardiac damage caused by myocardial infarction, and therefore has a good application prospect.

A system for percutaneous ventriculoplasty. Anchors can be placed in the ventricular septum and the ventricular wall. Sutures tethered to the anchors can be tensioned to reduce the size of a dilated left ventricle. Multiple anchors can be positioned in the ventricular wall and the sutures can be independently tensioned to allow tailored treatment of the dilated ventricle.

The application provides a multi-inlet blood pumping device, and relates to the technical field of medical apparatuses.The blood pumping device comprises a pipe body, a pump assembly and a one-way valve; the head end of the pipe body enters the left ventricle after passing through the aorta; the tail end is connected with the pump assembly; the pipe body comprises a plurality of blood pumping vessels; the blood pumping vessels are provided with an inlet in the left ventricle and an outlet in the pipe wall located in the aorta; the blood pumping vessels are provided with the one-way valve; the one-way valve controls the outlet to be closed and the inlet to be opened when the blood pumping vessels pump blood; the inlet is closed and the outlet is opened when blood is transfused; the blood pumping vessels comprise a proximal apical pipe and a distal apical pipe; the pump assembly is electrically connected with a controller, and the controller controls the proximal apical pipe to pump blood first and the distal apical pipe to pump blood later.In the application, the blood in the left ventricle is layered and evacuated, the left ventricle side wall is driven to move in accordance with a healthy rhythm in the diastolic phase and the systolic phase, the blood flow movement of the intraventricular coronary artery and the coronary microcirculation is improved, the myocardial cell repair is promoted, and the symptoms of myocardial contraction weakness of the patient are effectively relieved.

The invention discloses a supporting main body, a far-end component, an axial flow blood pump and a control method thereof, the supporting main body comprises a connecting part, the connecting part penetrates through the near end of the connecting part to form an extension cavity communicated with a pump cavity of a pump body, and the connecting part is further provided with a blood inlet communicated into the extension cavity. The at least two blood inlets are the first blood inlet and the second blood inlet, the first blood inlet is located on the near side of the second blood inlet, a first included angle is formed between the first blood inlet and the central axis of the pump cavity, a second included angle is formed between the second blood inlet and the central axis of the pump cavity, and the first included angle is smaller than the second included angle. The application helps to slow down periodic swing of the support body, and then reduce damage to an interventional site such as a ventricular wall.

The invention discloses a heart left ventricle modeling image ventricle wall thickness calculation processing method, which comprises the following steps of: reconstructing a personalized three-dimensional left ventricle model based on a patient heart magnetic resonance image, solving a myocardial transmural gradient by adopting a Laplace-Dirichlet parameterization method, and dividing a ventricle wall into a plurality of layers; through a layered mapping strategy, determining a mapping point between the myocardium of the inner layer and the myocardium of the outer layer by adopting a method of combining cone space search and Laplace-Dirichlet value matching, and completing mapping between the outermost layer and the ventricular outer membrane by adopting a nearest neighbor algorithm; and finally, through layer thickness real-time accumulation and data post-processing, obtaining accurate left ventricular wall thickness distribution data. The method overcomes the defect that a rigid mapping method easily generates measurement deviation when facing pathological forms such as myocardial fibrosis and ventricular wall tumors, improves the precision and reliability of ventricular wall thickness measurement, and provides effective technical support for accurate diagnosis, treatment planning and dynamic monitoring of cardiovascular diseases.

The present invention relates to a medical device for anchoring a heart pump in an opening in a ventricular wall of a heart, comprising a connector (10) intended to be mounted on said ventricular wall.According to the invention, - this connector (10) comprises an assembly flange (11) and a support skirt (12), extending from this assembly flange (11), this support skirt (12) being intended to be placed outside the heart when the assembly flange (11) is assembled to the ventricular wall, this connector (10) defining a first opening for the passage of a part of the body of an insert (14), - this insert (14) being entirely rigid and defining a second opening for the passage of the body of the cardiac pump, this insert (14) comprising a distal end intended to be placed inside the heart and a proximal end intended to be placed outside the heart when this insert (14) is mounted on the connector (10), and - at least one locking / unlocking element (19) in the position of the insert (14) relative to the connector (10), when this insert (14) has been introduced into the connector (10). [Fig. 1].

The embodiment of the utility model relates to the field of mechanical devices for driving circulation in ventricles, in particular to a ventricle assisting device and assembly. The ventricle auxiliary device comprises a tube body, a pump, a separator and a guide wire, wherein the guide wire is arranged to be capable of conveying the separator to a preset position of a ventricle; the tube body provides a flowing channel for blood, and a blood inlet and a blood outlet are formed in the two ends of the tube body respectively. The pump is arranged at the blood outlet of the tube body and is used for pumping blood; the isolation piece is arranged at the blood inlet of the tube body and wraps the blood inlet of the tube body, and the isolation piece is arranged to enable blood to enter the blood inlet through the isolation piece and enable the tube body not to touch the ventricular wall in the blood suction process. The utility model further provides a ventricular assist assembly which comprises the ventricular assist device and a sheath assembly, and the sheath assembly is arranged to block the blood outlet before the ventricular assist device enters the blood vessel of the user when the ventricular assist device is fed into the ventricle, so that blood is prevented from flowing out of the blood outlet.

An epicardial implant system prevents right heart failure following left ventricular assist device (LVAD) implantation through dual-mechanism support of the right ventricular free wall and tricuspid valve annulus. The device comprises a biocompatible independent adjustment mechanisms for ventricular wall constraint and annular geometry optimization. The invention simultaneously treats both ventricular dilation and annular valve dysfunction through separate adjustable elements. Epicardial placement eliminates atriotomy requirements while providing real-time hemodynamic optimization. Atraumatic anchoring permits repositioning without tissue damage. Preclinical validation confirms six-minute implantation with independent component efficacy under afterload conditions. The ventricular component prevents dilation while the annular component reduces regurgitation, validating dual-mechanism necessity. The prophylactic approach addresses mechanical disruption causing right heart failure in 40% of LVAD recipients. Applications extend beyond LVAD to coronary bypass, and valvular corrections. Biodegradable embodiments accommodate pediatric cardiac growth. The system provides the first dedicated prophylactic intervention for post-surgical right heart failure across multiple cardiac procedures.

Embodiments of the present application relate to the field of mechanical devices for driving circulation within the ventricles, and in particular, to a ventricular assist device and assembly. The ventricular assist device provided in the present application comprises: a tube body, a pump, an isolation member, and a guide wire. The guide wire is configured to be capable of transporting the isolation member to a predetermined position of a ventricle. The tube body provides a flow channel for blood, and a blood inlet and a blood outlet are formed at two ends of the tube body, respectively. The pump is disposed at the blood outlet of the tube body and is configured to pump the blood. The isolation member is disposed at the blood inlet of the tube body and covers the blood inlet of the tube body, and the isolation member is configured to allow the blood to enter the blood inlet through the isolation member, ensuring that the tube body does not come into contact with the ventricular wall during the blood suction process. The present application further provides a ventricular assist assembly, which comprises the ventricular assist device and a sheath assembly. The sheath assembly is configured to block the blood outlet before the ventricular assist device enters a blood vessel of a user during the delivery of the ventricular assist device into the ventricle, so as to prevent blood from flowing out of the blood outlet.