30 results about "Ventricular cavity" patented technology

The invention belongs to the technical field of medical instrument experiments, and particularly relates to a ventricle simulator and an in-vitro blood circulation simulation device simulating cardiac pulsation. The ventricular simulator comprises a ventricular cavity, a ventricular simulator body, a ventricular simulator body and a ventricular simulator body, the bionic ventricle is hollow, openings are formed in the two transverse ends of the bionic ventricle, the bionic ventricle can be contracted or relaxed and is transversely arranged in the ventricle cavity, and the two ends of the bionic ventricle and the two ends of the ventricle cavity are sealed and fixed through a front connecting cover and a rear connecting cover, so that the interior of the bionic ventricle is separated from the ventricle cavity; the front connecting cover and the rear connecting cover are each provided with a transverse communicating opening communicating with the interior of the bionic ventricle. The ventricle simulator innovatively realizes complete isolation of an internal circulation system and an external driving system, reduces external interference and pollution, and ensures stable operation.

The present invention relates to a method and system for monitoring cardiac functions and quantifying objective, operator-independent indices of cardiac functions. The invention quantifies both ventricle cavity and wall dynamics. It provides a picture with a comprehensive view of the six phases of cardiac contraction, relaxation and filling (isovolumic contraction, ejection, isovolumic relaxation, rapid filling, diastasis and atrial kick). It enables to quantify the effect of respiration and mechanical ventilation on cardiac chamber loadings and thereby to optimize mechanical ventilation in the general and cardiac intensive care units. It enables to assess the phase differences between the electrical activations and mechanical contractions of the various chambers and thus to adjust and optimize the parameters of cardiac synchronization therapies of ventricle chambers and chamber walls (as cardiac resynchronization therapy).

The invention relates to a multifunctional heart pulsation simulation system, which comprises a ventricle simulation mechanism, an atrium simulation mechanism, an artery simulation mechanism and a backwater mechanism, and is characterized in that the ventricle simulation mechanism comprises a ventricle cavity and a pulsation pump; the atrial simulation mechanism comprises an atrial cavity connected with the ventricular cavity and an atrial compliance cavity connected with the atrial cavity, and a first valve carrier is detachably mounted at the joint of the ventricular cavity and the atrial cavity; the artery simulation mechanism comprises an artery water inlet cavity connected with the ventricular cavity, an artery water outlet cavity connected with the artery water inlet cavity, an artery compliance cavity arranged at the top of the artery water outlet cavity and an artery root compliance cavity arranged at the bottom of the artery water outlet cavity; a second valve carrier is detachably mounted at the joint of the artery water inlet cavity and the artery water outlet cavity; the water return mechanism is connected between the atrial compliance cavity and the artery compliance cavity. According to the invention, two types of valves are simultaneously placed in the system for testing, so that the accuracy of a test result is effectively improved.

A ventricular assist device that can be used for ventricular aneurysm includes a stent, the stent having a first end and a second end opposite to each other, a polymer film attached to the first end of the stent, a base provided at the second end of the stent, and a force-bearing portion formed between the first end and the second end of the stent, which can spontaneously adapt to the contraction and relaxation movements of the heart. That is, when the force-bearing portion contracts radially under force, the stent stretches axially; when the external force disappears and the force-bearing portion is not radially stressed, the stent returns to its original state. A skirt is provided at the edge of the polymer film, and one end of the skirt away from the polymer film is reversely adhered to the polymer film. When the stent enters the ventricle, the portion of the skirt that is reversely adhered to the polymer film is separated from the polymer film and adsorbed to the ventricular cavity wall, thereby reducing or even solving the problem of residual leakage after surgery.

An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male and female fasteners, a coupler, a driveline assembly, and a co-pulsatile driver. Forward and backward flow communication between the blood pump and the heart chamber is accomplished using the present flow cannula invention which is anastomosed to the heart chamber in a sutureless manner. When providing circulatory support, the co-pulsatile driver ejects blood out of the blood pump during systolic ventricular contraction and fills the blood pump with blood during diastolic ventricular relaxation.

The present application relates to a TAVR teaching model based on blood flow simulation and multi-modal image fusion and use method. The model comprises a simulated thoracic and abdominal cavity with a built-in heart wave beat simulation part that drives fluid to generate pulsatile blood flow, a simulated thoracic and abdominal body with pre-set vascular access, a bionic heart assembly with structures such as a ventricular cavity, a pathological valve module that can be detachably fitted to the aortic valve ring and contains a pressure sensor array and simulated calcification, a coronary circulation monitoring module that monitors the perfusion state of the coronary artery opening, a virtual fluoroscopy positioning module that generates real-time fluoroscopy images, and a central control console that electrically cooperates with each module. The scheme simulates the tactile sensation of calcification through the pathological valve module, the heart wave beat simulation part reproduces the physiological pressure difference with a closed loop blood flow, realizes image navigation training with non-radiation virtual fluoroscopy, integrates real-time simulation of complications with coronary monitoring and annulus pressure sensing, and solves the problems of existing models such as distorted hand feeling, inaccurate dynamics, dependence on radiation, and lack of complication training.

The present document relates to a device for fixing a cardiac pump in an opening of a ventricular wall of a beating heart. The device includes: a hollow main body of overall cylindrical shape having an outer surface, this hollow main body includes a proximal end and a distal end between which said the outer surface extends, at least one portion of the outer surface of the main body intended to be placed inside ventricular cavity, except for its distal end, has a surface relief provided with protuberances and hollows, the distal end of the hollow main body forms a smooth crown having an arithmetic average roughness of less than or equal to 1 μm in order to stop the colonization of the fixing device by endothelial cells.

The utility model discloses a ventricle simulation device and an in-vitro amplification test system. The ventricle simulation device comprises a simulation ventricle, a mounting frame and a guide rail sliding block assembly. The simulated ventricle is provided with a ventricle cavity, the mounting rack is used for mounting the simulated ventricle, and the guide rail slide block assembly comprises a guide rail and a slide block and is arranged between the simulated ventricle and the mounting rack to realize relative sliding between the simulated ventricle and the mounting rack. A user can realize connection and disconnection between the simulation ventricle and other components by moving the simulation ventricle, or the simulation ventricle is utilized to drive a linkage component to be connected and disconnected with other components, rapid connection and disconnection of an in-vitro amplification test loop can be realized, and the test efficiency is improved under the condition that the performance test requirement of a catheter pump model is met. And the rapid dismounting and replacement of the conduit pump model in the in-vitro amplification test system are facilitated.

The embodiment of the invention provides a ventricular auxiliary circulation device and a control method. The ventricular auxiliary circulation device comprises at least one shell, and the shell is attached to a specific area of the outer surface of a ventricular chamber in shape; and a drive device linked to the at least one housing, where the drive device exerts a periodic external effect on the housing to cause the housing to periodically contract, thereby periodically extruding the ventricular cavity to promote ventricular blood circulation.

The utility model relates to a simulation circulation device for in-vitro research of aortic diseases, which comprises a disease simulation box, a ventricular cavity, a venous cavity and an arterial cavity which are sequentially connected through a circulation pipeline to form a closed loop for simulating blood circulation flow. A first one-way valve which is in one-way conduction from the simulation box to the ventricular cavity is arranged on the circulating pipeline between the disease simulation box and the ventricular cavity; and a second one-way valve which is in one-way conduction from the ventricular cavity to the venous cavity is arranged on the circulating pipeline between the ventricular cavity and the venous cavity. The simulation circulation device for in-vitro research on the aortic diseases is low in research cost, small in risk, high in use flexibility and capable of realizing in-vitro research on the influence of the aortic diseases on cardiovascular physical parameters of a human body.

A flow field testing system and method for a cardiac valve device are disclosed. The flow field testing system includes a ventricular simulation module with a ventricular cavity, which is formed by multiple sidewalls surrounding the cavity. The sidewalls include a first sidewall and a second sidewall that are horizontally opposite each other. A flexible deformable first diaphragm and a second diaphragm are respectively disposed on the first sidewall and the second sidewall. The first diaphragm and the second diaphragm are separated by a rigid structure. The ventricular simulation module also includes a driving unit that applies pressure to the first diaphragm and the second diaphragm, respectively, driving the first diaphragm and the second diaphragm to deform simultaneously toward or away from the ventricular cavity to simulate the contraction or relaxation of the ventricle. The flow field testing method applies different pressures to the first diaphragm and the second diaphragm by the driving unit.

The present disclosure provides a cardiac phase recognition method, device, equipment and storage medium, to realize multi-frame automatic segmentation and accurate cardiac phase recognition. The cardiac phase recognition method comprises: selecting an initial segmentation frame in the ventricular contrast sequence image data; performing ventricular boundary recognition based on the feature points marked in the initial segmentation frame to determine the ventricular boundary contour; for the image frame adjacent to the initial segmentation frame, taking the ventricular boundary contour of the initial segmentation frame as the starting contour, emitting a ray in a narrow band range to search for a boundary point in a polar coordinate manner, connecting the boundary points and performing region-driven segmentation to obtain the ventricular boundary contour; taking the image frame as a new initial segmentation frame, repeating the above steps for the next image frame to obtain the full sequence ventricular boundary contour; determining the ventricular cavity area sequence corresponding to the ventricular contrast sequence image data based on the full sequence ventricular boundary contour, and dividing the cardiac phase according to the ventricular cavity area sequence.

A system for monitoring cerebrospinal fluid (CSF) intracranial pressure and shunt flow in a hydrocephalus patient. It may include a ventricular catheter, a peritoneal catheter and a valve in fluid communication with the catheters. Piezoelectric pressure sensors may be disposed on each end of the catheters. An intracranial electret pressure sensor may be disposed on the ventricular cavity end of the ventricular catheter. A processing and transmission module may determine pressure values at each of said sensors, compute shunt flow comprising ventricular catheter and peritoneal catheter flow rates, and cause a wireless data transmitter to transmit a CSF pressure value and shunt flow to an external receiver.

The invention relates to the technical field of blood circulation simulation devices, and provides an in-vitro simulation circulation test system driven by double power sources, which comprises a heart module, a lung module and a blood vessel branch module, the heart module comprises a motor pump group branch and a gas-liquid converter branch which are connected in parallel, and a motor pump group and a gas-liquid converter are respectively used as power sources; the motor pump set branch and the gas-liquid converter branch are respectively connected to the ventricular cavity through a reversing valve, and the reversing valve is used for switching the flow direction of the in-vitro simulation cycle test loop, so that the motor pump set or the gas-liquid converter is selected to drive the ventricular cavity, and simulation of different pressure waveforms and pulsation rhythms of the ventricle is realized. The system not only has high response control capability, but also can simulate flexible and slowly changing ventricular pulsation characteristics. According to the structure, the problems that a traditional system is single in driving mode and poor in adaptability are effectively solved, and the simulation precision and the adaptation capacity of various cycle scenes are remarkably improved.

A physiological control system for a blood pump includes a controller configured to receive an input signal indicative of ventricular chamber volume, and generate an output pump control signal based on the input signal. A physiological method for controlling a blood pump is also disclosed.

Provided are devices and methods for augmenting mitral valve function. A cardiac valve prosthesis device comprises a stent frame assembly having an atrial portion and a ventricular portion, a peripheral ring attached to the stent frame assembly, which divides the stent frame assembly into the atrial and ventricular portions, and a plurality of valve leaflets fixedly coupled to the stent frame assembly. The peripheral ring fits over a native mitral valve annulus when the prosthesis device is implanted in a native mitral valve. The peripheral ring limits the protrusion of the stent frame assembly into a ventricular chamber and reduces the effect on ventricular outflow or excursion of a native leaflet by such protrusion.

The invention discloses a forming device for treating heart ventricular wall tumors, and relates to the technical field of medical instruments, the forming device comprises an air bag, the air bag is provided with an air vent, the air vent is connected with an air pipe, and the shape and the size of the air bag after inflation are matched with those of a ventricular cavity, needing an operation, of a patient; the end, away from the air bag, of the ventilation pipe communicates with an air outlet of the inflation device, and the inflation device is used for inflating the air bag; the conveying catheter is used for being placed at a crevasse formed after the lesion bulged ventricular wall of the heart of the patient is cut off, and the conveying catheter serves as a channel for the air bag to enter and leave the ventricle. By means of the technical scheme, patch patching in an operation can be assisted, the accuracy of the shape and the size of the patch is improved, then the situation that the ventricular volume and the shape of a patient are changed after patch patching is avoided, the reduction degree of the original form of the ventricle in the ventricular wall tumor treatment process is effectively improved, and the postoperative cardiac function and ventricular wall movement conditions of the patient can be improved.

The invention relates to the technical field of medical images, and provides a method and equipment for reconstructing a personalized heart model with an infarction region, and a medium. The method comprises the following steps: preprocessing a heart magnetic resonance delay gadolinium enhanced CMR-LGE image of a patient to obtain a first high-resolution tag image containing a ventricular cavity and infarction tissue, and constructing a heart finite element mesh model based on high-precision heart cavity data of the patient; performing direction adjustment on the first high-resolution label image to obtain a second high-resolution label image; and mapping the infarction region in the second high-resolution label image into the heart finite element mesh model to obtain a personalized heart model with the infarction region. Based on the scheme of the invention, the accuracy of the reconstruction of the personalized heart model with the infarction region can be improved.

The application discloses a heart pacemaker electrode guide wire shaping device in the technical field of heart pacemaker implantation, which comprises a guide clamp seat, clamping columns, clamping blocks and lifting columns, the vertical side wall is an arc surface, a plurality of clamping columns are arranged in an arc line on the top of the guide clamp seat in a uniform manner, and the vertical side wall on one side of each clamping column is protruded outside the inner arc surface of the guide clamp seat, the specific shape can hold the electrode guide wire at a specific angle, the electrode guide wire can be pulled and shaped from the holding with the specific arc, stable deformation with a set angle is formed, the arc of the guide clamp seat can be changed, the size and shape of the ventricle cavity of a patient are adjusted, so that the arc of the guide wire shaping is changed, and the deformation and angle of the electrode guide wire are more suitable for the size, angle and the like of the ventricle cavity of the corresponding patient, meanwhile, the shaping of the electrode guide wire is more convenient, the shaping angle is more stable, and the success rate is higher.

The present disclosure provides a cardiac phase recognition method, device, equipment and storage medium, to realize multi-frame automatic segmentation and accurate cardiac phase recognition. The cardiac phase recognition method comprises: selecting an initial segmentation frame in the ventricular contrast sequence image data; performing ventricular boundary recognition based on the feature points marked in the initial segmentation frame to determine the ventricular boundary contour; for the image frame adjacent to the initial segmentation frame, taking the ventricular boundary contour of the initial segmentation frame as the starting contour, emitting a ray in a narrow band range to search for a boundary point in a polar coordinate manner, connecting the boundary points and performing region-driven segmentation to obtain the ventricular boundary contour; taking the image frame as a new initial segmentation frame, repeating the above steps for the next image frame to obtain the full sequence ventricular boundary contour; determining the ventricular cavity area sequence corresponding to the ventricular contrast sequence image data based on the full sequence ventricular boundary contour, and dividing the cardiac phase according to the ventricular cavity area sequence.

A biostimulator system includes a biostimulator (100) having a header module (150) and a housing module (152). The header module (150) includes a fixation element (106), a pacing electrode (108), and an electrical pin (304). The housing module (152) includes pacing circuitry that is electrically connected to a power source (206), and an electrical socket (306) to receive and electrically connect the electrical pin (304) to the pacing circuitry. The biostimulator system includes a biostimulator transport system (503) to deliver the header module (150) to an interventricular septal wall (104) and to deliver the housing module (152) to a ventricular chamber. The modules (150, 152) are then electrically connected within the ventricular chamber. Other embodiments are also described and claimed.

The invention discloses a blood circulation simulation device for a vascular intervention operation, and the device comprises a vein simulation pipeline which is provided with a vena cava, a pulmonary vein, and a vein capillary; the artery simulation pipeline is provided with an aorta, a pulmonary artery and an arterial capillary; the heart simulation pump is provided with a left atrium, a left ventricle, a right atrium and a right ventricle; the vena cava is communicated with the right atrium, the pulmonary vein is communicated with the left atrium, the aorta is communicated with the left ventricle, and the pulmonary artery is communicated with the right ventricle. Real blood vessels are simulated by arranging the vein simulation pipeline and the artery simulation pipeline, the left atrium, the left ventricle, the right atrium and the right ventricle of a real heart are simulated by arranging the heart simulation pump, the left atrium, the right atrium, the left ventricle and the right ventricle are alternately contracted in an air pressure control mode, and the contraction state of the heart is truly simulated; a real blood flow state is simulated in the vein simulation pipeline and the artery simulation pipeline, and a real interventional operation environment is provided for training and learning.

A method for ventriculostomy of the cavity of the anterior horn of the lateral ventricle in children, characterized by the fact that a calculation is carried out before the start of operative correction, based on the data of preliminary neuroimaging of the brain in the frontal and sagittal planes, while aligning the obtained images along the coordinate axes, the first side in determining the key point is selected in the projection of the widest part of the ventricular cavity, retreating from the coronary suture to the ventral side from 0 mm to 10 mm; the second side in determining the key point is selected in the frontal plane in the projection of the widest cavity of the anterior horn of the lateral ventricle of the brain, from the side of catheter placement, its maximum width is determined, the final result obtained is divided in half, the results of the two sides for determining the key point are transferred to the cranial vault;intraoperatively, a ventricular catheter is inserted through the key point parallel to the sagittal suture, and its insertion tip is directed to the imaginary biauricular line.

An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male an

The present invention discloses a pacing electrode lead assembly that is automatically fixed in the left ventricle. The pacing electrode lead comprises a lead body, a head end, and a plug for connecting to a pulse generator. The lead body is arranged between the plug and the head end. The plug and the rear end of the lead body are integrally constructed. The front end of the lead body is detachably connected to the head end. When the head end reaches the left ventricular cavity, the head end opens to form an umbrella structure. The present invention solves the problem that the head end of the pacing electrode lead cannot be fixed in the left ventricular cavity.

Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum. A tension member may extend from that anchor through the septum and an exterior wall of the left ventricle to a second anchor disposed along a surface of the heart. Perforating the exterior wall and the septum from an epicardial approach can provide control over the reshaping of the ventricular chamber. Guiding deployment of the implant from along the epicardial access path and another access path into and through the right ventricle provides control over the movement of the anchor within the ventricle. The joined epicardial pathway and right atrial pathway allows the tension member to be advanced into the heart through the right atrium and pulled into engagement along the epicardial access path.

The invention discloses a multipurpose indwelling cardiac apex puncture cannula and a using method thereof. The cardiac apex puncture cannula comprises a puncture needle, an indwelling sheath tube, a plugging device and a conveying tube. The puncture needle is used for penetrating into the indwelling sheathing canal and guiding the indwelling sheathing canal to puncture the cardiac apex, and an inner cavity of the indwelling sheathing canal is used for establishing a multipurpose channel; the indwelling sheath tube comprises a catheter body and an operating handle, and the operating handle is fixedly connected to the near end of the catheter body; the plugging device comprises a plugging core and a plugging cap. The far end of the plugging core is used for being inserted into an inner cavity of the indwelling sheath tube to plug the multipurpose channel. The plugging cap is fixedly connected to the near end of the plugging core and used for being in sealed connection with the operating handle. The delivery tube can penetrate into the indwelling sheath tube, extends to the ventricular cavity and is used for delivering medical instruments to the ventricular cavity. According to the invention, an interventional pathway which is shorter, safer, higher in adaptability and capable of being indwelled for a long time can be established at the cardiac apex position, and clinical requirements of cardiac structural disease interventional therapy, extracorporeal circulation support, multiple interventional therapy and the like are met.

A biostimulator system includes a biostimulator having a header module and a housing module. The header module includes a fixation element, a pacing electrode, and an electrical pin. The housing module includes pacing circuitry that is electrically connected to a power source, and an electrical socket to receive and electrically connect the electrical pin to the pacing circuitry. The biostimulator system includes a biostimulator transport system to deliver the header module to an interventricular septal wall and to deliver the housing module to a ventricular chamber. The modules are then electrically connected within the ventricular chamber. Other embodiments are also described and claimed.

This invention provides a zebrafish model of hypertrophic cardiomyopathy characterized by ventricular cavity shrinkage and reduced mobility, and a method for constructing the model. Using zebrafish tmem260 as the target gene, CRISPR / Cas9 technology is used to microinject in vitro designed and synthesized tmem260-specific sgRNA and Cas9 protein into wild-type zebrafish fertilized eggs. After successive generations of screening, tmem260 gene-specific knockout zebrafish mutants are obtained. The phenotype of hypertrophic cardiomyopathy characterized by ventricular cavity shrinkage and reduced mobility in the mutants is observed and passaged for conservation.

This invention discloses a method, electronic device, and storage medium for detecting imaging features of hydrocephalus based on neural networks. The method includes collecting and labeling brain imaging data of patients with normal pressure hydrocephalus, and performing preprocessing; using a neural network to segment the ventricular region in thick-slice brain imaging data to generate a binary image sequence; training a neural network model for interpolation using thin-slice brain imaging data, continuously adjusting parameters until optimal; inputting the binary segmentation result of the thick-slice image along with the original thick-slice image into the trained interpolation network, outputting an interpolated binary segmented image; counting the number of voxels in the ventricular portion of the interpolated binary segmented image, and calculating the actual volume of the ventricular cavity based on the image scanning interval information. This invention reduces the error in calculating ventricular volume by segmenting images when the scanning interval is too large, obtaining accurate ventricular volume data, thereby optimizing the computer-aided diagnosis process for hydrocephalus.