146 results about "Aorta" patented technology

The utility model relates to a large area contact type thread type degradable magnesium alloy aortic blood vessel anastomat, including the conical inner ring, conical outer ring and sleeve outer ring that set gradually from inside to outside, be provided with blood vessel clamping space between the conical inner ring and conical outer ring, it is the thread cooperation between conical outer ring and sleeve outer ring, adjust the size of blood vessel clamping space through the rotation sleeve outer ring, sleeve outer ring. The utility model simple structure, reasonable in design, convenient to use, adjust the size of blood vessel clamping space through the rotation conical outer ring and sleeve outer ring to fixed blood vessel, realize blood vessel anastomosis fast, avoid the mode of the traditional everted type through end face combination simultaneously, greatly increase the contact area between blood vessel and prevent the occurrence of blood leakage.

The invention discloses application of gynostemma pentaphyllum polysaccharide to prevention of vascular wall thickening caused by space microgravity and a medicine, the gynostemma pentaphyllum polysaccharide is applied to prevention of vascular wall thickening caused by space microgravity and the medicine for prevention of vascular wall thickening caused by space microgravity, and the medicine contains the gynostemma pentaphyllum polysaccharide; the gynostemma pentaphyllum polysaccharide reduces thickening of blood vessel walls by inhibiting proliferation and migration of vascular smooth muscle cells, can be used for preventing or treating aorta blood vessel wall thickening caused by space microgravity, and is suitable for health guarantee of astronauts in long-term space missions.

Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.

A delivery system for delivering a prosthetic valve in a compressed condition over an inner shaft of a catheter. The delivery system includes a tip extending distally from the inner shaft. The tip has a proximal section and an opposite distal section extending to an end of the tip. The proximal section is configured to support an end of the prosthetic valve during loading and delivery of the prosthetic heart valve and includes a first portion, a second portion, and a third portion. The first portion is adjacent the distal section. The second portion is between the first portion and third portion. The third portion is adjacent a proximal end of the tip. An outer diameter of the first portion is greater than an outer diameter of the inner shaft, an outer diameter of the second portion, and an outer diameter of the third portion.

The invention discloses a staged pump speed regulation and control implementation method for improving VA-ECMO cycle stability, and relates to the technical field of biomedical engineering. The method comprises the following steps: acquiring a real-time aorta pressure waveform, a peripheral artery pressure waveform and an ECMO post-pump pressure waveform of a patient, and extracting pulse wave characteristics, a pressure oscillation amplitude and phase deviation information; calculating a heart-ECMO blood flow intersection collision intensity index and evaluating a heart load state grade; acquiring a vascular compliance estimated value of a patient, and determining a target pump speed adjusting mode and adjusting amplitude according to a hierarchical regulation strategy library; and the current actual pump speed is obtained, a speed regulation decision is made, the ECMO pump is driven to execute graded stepped pump speed regulation, and the regulation speed is dynamically corrected in real time in the regulation process until the cyclic stable interval is reached. Quantitative evaluation and self-adaptive regulation and control of the pump speed are achieved, hemodynamic fluctuation is inhibited, and the stability and safety of VA-ECMO cycle support are improved.

The invention provides a ventricular elasticity value estimation method and device.The method comprises the steps that a first parameter and a second parameter are obtained, the first parameter comprises at least one of target ventricular pressure, target aortic pressure and target pulmonary arterial pressure of a target user, and the second parameter comprises at least one of the target ventricular pressure, the target aortic pressure and the target pulmonary arterial pressure; the second parameter comprises the pumping flow of the target ventricular assist device and the cardiac cycle of the target user; inputting the first parameter and the second parameter into a target decision model, and outputting a target ventricular volume; and estimating a target ventricular elasticity value according to the ratio of the target ventricular pressure to the target ventricular volume. The ventricular volume of the current user is estimated through the decision model, the estimated ventricular elasticity value is calculated according to the ratio of the ventricular pressure to the ventricular volume, and the ventricular elasticity value of the patient can be accurately predicted in real time without depending on ultrasonic equipment.

The invention belongs to the technical field of biological medicine, and particularly provides application of flufenidone in preparation of a medicine for preventing or treating left heart failure. The research finds that the flufenidone has the effects of relieving myocardial cell hypertrophy under a heart failure cell model and relieving myocardial hypertrophy, fibrosis and heart function deterioration of an aortic constriction animal model. According to the present invention, further research results show that fluorofenidone is directly combined with SERCA2a through Q758, D812 and E917 residues of SERCA2a so as to inhibit recognition, combination and polyubiquitination effects of WWP1 on SERCA2a, such that the protein level and the activity of SERCA2a are stabilized so as to achieve the chronic left heart failure treatment purpose. Therefore, the flufenidone serving as an active ingredient has good application prospect and application value in research and development of novel medicines for treating chronic left heart failure.

This application relates to a blood pump, comprising a primary pumping device, a first catheter, a secondary pumping device, and a second catheter connected in sequence. The primary pumping device has a first inlet and a first outlet, and the secondary pumping device has a second inlet and a second outlet. The secondary pumping device includes a secondary cannula, which has a proximal end, a distal end, and an enlarged portion. The proximal end is adjacent to the second catheter and has a second outlet. The distal end is connected to the first catheter and has a second inlet. The two ends of the enlarged portion are smoothly transitioned to the proximal end and the distal end, respectively. This blood pump increases the blood volume pumped by the secondary pumping device, allowing most of the blood in the aorta to be accelerated by the secondary pumping device, thus significantly improving the pumping efficiency of the secondary pumping device.

The invention relates to the technical field of medical instruments, and particularly discloses a catheter handle, a catheter pump and a catheter pump system. According to the catheter handle, the perfusion liquid inflow connector, the artery pressure measuring liquid inlet connector, the artery pressure measuring liquid outlet connector and the catheter connector are arranged on the perfusion support, the perfusion liquid outflow connector is arranged on the coupling support, the perfusion support and the coupling support are large in size, and therefore the connectors can be conveniently arranged; the number of parts is reduced, so that the machining process of the guide pipe device is simplified; besides, the artery pressure measuring liquid inlet connector and the artery pressure measuring liquid outlet connector are arranged on the perfusion stent, the connectors can be conveniently arranged, an independent aorta pressure sensing channel is formed, and compared with the prior art, flowing of perfusion liquid used for sensing the aorta pressure is not prone to being interfered by other factors, and the perfusate can be used for sensing the aorta pressure. And thus, the aortic pressure sensing precision is improved.

The application provides a rotating type artificial mechanical heart valve, and belongs to the technical field of heart valves, and comprises: a valve ring; a valve leaflet group, which is rotationally arranged in the valve ring; when the valve leaflet group is in an open state, a spiral channel is formed in the valve ring; and when the valve leaflet group is in a closed state, the valve leaflet group limits blood flow through the valve ring; the rotating type artificial mechanical heart valve of the application forms a spiral channel with the same rotation direction as the blood rotation flow state when the valve leaflet group is in the open state; the spiral channel is arranged to effectively rotate the blood flow, generate corresponding spiral flow state, and the rotation of the outlet blood flow is beneficial to the full flow and development of the blood flow in the aorta, reduces the turbulence, stagnation area and damage to the normal rotation flow state in the aorta, and the heart valve provided by the application has excellent hemodynamic characteristics and can effectively inhibit the aortic dilation complication caused by aortic valve replacement.

The invention relates to a guide-wire-free integrated balloon catheter system, which comprises a balloon dilatation mechanism, a balloon catheter and a balloon catheter, the balloon dilatation mechanism comprises a first balloon, a second balloon and a balloon pushing rod, and the first balloon and the balloon pushing rod are arranged in a penetrating manner; the first balloon is used for blocking the aorta I region; the second balloon and the balloon pushing rod are arranged in a penetrating manner; the second balloon is used for blocking the aorta III region; a first outlet and a second outlet are respectively formed in the balloon pushing rod between the first balloon and the second balloon and in the other side of the second balloon, and a blood inlet is further formed in the other side of the first balloon; the blood inlet is communicated with the first outlet and the second outlet through a pipeline and is closed or opened through a valve, and the pipeline is located in the balloon pushing rod. The balloon is used for improving the hemostasis and plugging effects, meanwhile, avascular necrosis of internal organs and limbs below the plugging position can be prevented, the balloon can better play the hemostasis, plugging and other roles, and the hemostasis time is prolonged.

A neurovascular catheter for delivery through an aorta and into an ostium can include a tubular body between a proximal end to a distal end. The tubular body can have a length of 140 cm to 180 cm, a 5Fr size, and an internal diameter of about 0.065" to about 0.067". The tubular body can include a proximal portion and a distal portion. The distal portion can include a polymer layer and a layer of braids. The proximal portion can include a hypotube and the layer of braids.

The invention discloses a perfusion type kidney aorta blocking balloon assembly which comprises a balloon, one end of the balloon is communicated with one end of a communicating pipe, an injection pipe is arranged on the inner side of the balloon, the end of the injection pipe extends to the outer side of the balloon, and the ends, away from the balloon, of the injection pipe and the communicating pipe are each provided with a connector. The waterproof piece is slidably arranged outside the communicating pipe in a sleeving mode and comprises a water blocking cover and an adsorption cover, and the water blocking cover and the adsorption cover are arranged outside the communicating pipe in a sleeving mode and can slide along the outer wall of the communicating pipe; the water blocking cover is closer to the balloon than the adsorption cover, and the adsorption piece is used for adsorbing the adsorption cover to the skin surface of a patient. According to the blocking balloon assembly, when a surgical puncture hole for minimally invasive surgery and communicating pipe infusion is exposed, condensed water drops are isolated through the movable waterproof piece, the adsorption cover is tightly attached to the skin through the adsorption piece, the puncture hole is prevented from being polluted by the water drops, and air exposure of a wound is reduced; therefore, the infection probability is reduced and the surgical operation safety is improved.

A stent graft for treating an arterial aneurysm includes loops fixed to struts of stents, wherein the struts define distal and proximal apices. The ends of a ligature can be linked by a wire in a stent graft delivery system that threads anchor loops longitudinally spanning ends of the ligature to maintain the stent in a radially constricted position during delivery to the aneurysm. A delivery system and method for implanting a stent graft prosthesis includes and employs a torque component at a distal end of the stent graft prosthesis, whereby following advancement of the stent graft to a surgical site in a constrained or partially constrained configuration, torque is applied to the torque component to rotationally align the stent graft about a longitudinal axis of the stent graft, followed by deployment of the stent graft in correct rotational alignment. A delivery system and method of its use includes an apex capture assembly, a leg clasp, and a leg stop for capturing a stent graft during orientation and stabilization at an implantation site of a surgical site.

A method for performing a robotic-assisted orthotopic heart transplant includes forming a working port subareolarly by a mini-thoracotomy at a working intercostal space, forming additional ports for robotic arms, and arranging robotic arms through the ports. A first robotic arm with first forceps extends through a second port lateral to a mid-clavicular line, while second and third robotic arms containing an imaging device and second forceps operate through the working port. A fourth robotic arm with scissors or needle holder extends through a third port proximal to an anterior axillary line. The method includes cannulating for cardiopulmonary bypass, opening the pericardium, cross-clamping the aorta, removing the native heart, and performing sequential anastomoses of the donor heart including the left atrium, pulmonary artery, aorta, inferior vena cava, and superior vena cava.

A physical treatment device for rehabilitation of an old cardia-cerebrovascular disease patient belongs to the technical field of physical treatment instruments and comprises a bed body, an electrocardiogram monitor is arranged on one side of the bed body, a mattress is placed at the top of the bed body and comprises a first supporting pad and a second supporting pad, and the first supporting pad and the second supporting pad are hinged through a rotating shaft at the joint. The second supporting pad is provided with a physical treatment assembly used for assisting the elderly patient in rehabilitation treatment, through cooperation with the cardiac cycle of the patient, in the diastolic period, the driving motor is meshed with the synchronous rack through an incomplete gear, the air bag is sequentially inflated from the far end of the limb to the near end of the limb, blood vessels are pressed, and blood is driven back to the aorta; important blood vessel perfusion is added, myocardial ischemia and other symptoms are relieved, the device automatically exhausts air after the diastolic period ends, it is ensured that blood smoothly flows to the lower limbs, meanwhile, the whole device is combined with a bed body, and good rehabilitation treatment exercise can be achieved for paralyzed and disabled patients.

The invention discloses an IVUS-based guide wire-free blood vessel center line identification and navigation method, and relates to the technical field of blood vessel intervention and image navigation. The method comprises the following steps: arranging an IVUS transducer at the front end of an instrument, and synchronously obtaining an IVUS frame sequence and a probe pose; through cavity wall segmentation, center point extraction and time sequence-space fusion processing, a three-dimensional center line of the main blood vessel is constructed, and a safety envelope is generated; for a branch artery, branch super-selection navigation is realized through candidate sector detection, direction estimation and center line generation and splicing; meanwhile, a mismatch rollback and failure protection mechanism is set, so that navigation safety is ensured; the virtual center line is used for replacing a solid guide wire, the risk that blood vessels are punctured and mistakenly enter a false cavity is reduced, the radiography frequency and radiation exposure are reduced, the operation time is shortened, and the method is suitable for complex intracavity treatment scenes of aorta trunks and branches.

The present disclosure provides a transcatheter device including: an anchor (200) anchored to an inner wall of an inferior vena cava (IVC); and a main shaft (10) having a proximal shaft (110) that extends from the anchor (200) toward a tricuspid valve (TV) along a cavotricuspid isthmus (CTI) of a heart, a middle shaft (120) that extends from the proximal shaft (110), passes through the TV, and has a spacer (300) preventing a reverse flow in the TV mounted thereon, and a distal shaft (130) that extends from the middle shaft (120) into a pulmonary artery (PA), and the distal shaft (130) of the main shaft (100) includes a first distal part (131) that extends in a curved shape having a predetermined curvature from the middle shaft (120), a second distal part (132) that extends from the first distal part (131) and bends at point B1, which is one point that is over and surrounds an aorta, toward the proximal shaft (110), and a third distal part (133) that extends from the second distal part (132) toward the proximal shaft (110).

The invention discloses a neonatal umbilical artery and vein puncture catheterization training model which is characterized by comprising a neonatal model and a puncture needle model. A simulated heart is arranged in the thoracic cavity of the newborn model; the aorta and the inferior vena cava are connected with the simulated heart; the puncture needle model is rod-shaped, and a working part is arranged at the front end of the puncture needle model; the periphery of the vein puncture path and the artery puncture path is sleeved with a plurality of sets of electromagnetic coils in the axial direction; each group of electromagnetic coils is provided with an independent main switch, and the main switches of all the electromagnetic coils are arranged along a puncture path one by one, so that the main switch can be triggered when the working part of the puncture needle model passes through one main switch, and the corresponding electromagnetic coil is electrified to generate an acting force in a correct puncture direction on the working part. According to the invention, force sense direction guidance can be provided during puncture practice.

A medical implant device for proximal and distal anastomosis of the aorta is provided. The device is designed to facilitate connection between the aorta and the device, and the size of the two ends of the device is smaller than that of the aorta by one. The device is characterized in that protruding parts are arranged at the positions about 8 mm away from the two ends of the device, and the protruding parts are specially designed to be used for assisting installation of suture rings and used for tightening the aorta and blocking blood flow between the device and the aorta respectively. Once heated or in contact with blood, the constriction sleeve tightly secures the blood vessel and device before and after the protrusions. The design of the device aims to simplify the anastomosis process, reduce the time and skills required by the surgeon to perform the procedure, and improve the overall safety and effectiveness of the anastomosis.

The application provides an aorta morphological feature automatic measurement and clinical auxiliary decision-making method and system based on artificial intelligence, which is suitable for three-dimensional medical image analysis of aorta and its main branches. The method comprises the following steps: image data acquisition and preprocessing, automatic blood vessel structure segmentation, center line extraction and key point positioning, multi-parameter automatic measurement, risk assessment and clinical auxiliary decision-making, data standardization output and system feedback optimization. The corresponding system comprises an image acquisition and processing module, a segmentation module, a center line extraction module, a parameter measurement module, an auxiliary decision-making module, a data output module and a verification and optimization module. Through a deep learning model and morphological calculation means, efficient identification and quantitative analysis of blood vessel structure are realized, and individualized risk suggestions and surgical planning are output based on statistical and machine learning models. The application improves the automation, standardization and intelligence level of blood vessel analysis, and enhances the clinical auxiliary decision-making ability under complex cases.

A computer-implemented method for simulating an interaction between an endoprosthesis dedicated to be implanted in a portion of a patient aorta and said portion of the patient aorta, so as to determine areas with risk of surgical complications.

The utility model relates to heart and lung surgery extracorporeal circulation instrument technical field, especially point to a kind of intubation for aortic perfusion, it includes pipe head, tube body and balloon, pipe head and tube body are all hollowly arranged, and blood perfusion passage is formed in tube body;The front end of pipe head is communicated with the rear end of tube body, and the sidewall of the front end of tube body is respectively provided with first through-hole and second through-hole, first through-hole is located inside balloon, and the both sides of tube body are respectively provided with balloon channel and exhaust channel, the rear end of balloon channel is connected with first lead-out pipe, the rear end of exhaust channel is connected with second lead-out pipe, the rear end of first lead-out pipe is provided with first valve, and the rear end of second lead-out pipe is provided with second valve.The utility model realizes the inflation of balloon, realizes the blockage of blood vessel;The gas generated in perfusion blood supply process is extracted, and the effectiveness of perfusion blood supply is further improved;Blood perfusion passage, balloon channel and exhaust channel are respectively separated and independently work, and work reliably and stably.

The invention discloses a cleaning device for circulating liquid in an organ perfusion system, relates to the technical field of organ culture, and solves the problems that a traditional cleaning device interferes with main circulation, waste removal is not thorough, and perfusion is broken during maintenance. The perfusion system body comprises an aorta side / portal vein side liver inlet pipeline, a liver outlet liquid return pipeline, a liquid storage bag, an organ container and a four-pump body assembly, the double liver inlet pipelines are in butt joint with a liver aorta and a portal vein respectively, and the liver outlet pipeline is connected with the liquid storage bag through a third pump body; the cleaning device comprises a filter which is connected with the liquid storage bag in parallel and connected with a fourth pump body in series to form auxiliary circulation, the filter is divided into first-stage permeation filtration and second-stage dialysis membrane filtration, and a bypass pipeline with a valve / three-way switch is further arranged; the device ensures the stability of main circulation, efficiently removes waste in a grading manner, does not interrupt perfusion during maintenance, and assists in maintaining the in-vitro activity of organs.

According to an aspect of the present invention, there is provided a method for imaging vasa vasorum density of a vessel in the body such as coronary and carotid arteries and the aorta and thereby assessing the risk of adverse health outcomes for a patient, comprising administering a contrast agent to the patient; performing a contrast-enhanced CT scan to measure Hounsfield distribution and heterogeneity related to vasa vasorum density in and around the vessel wall of a patient; analyzing the data to determine a metric related to the density of the vasa vasorum; and recommending a diagnostic and / or therapeutic next step to the patient to prevent adverse health outcomes based at least in part on the metric related to the vasa vasorum density.

A vascular implant is provided for increasing the efficiency of blood flow through an aorta. The vascular implant includes a tubular shunt having a lumen for allowing blood to pass between an aorta and an inferior vena cava. An expandable reservoir is sized for placement in the inferior vena cava. The reservoir has a first region coupled to the tubular shunt and may include a second region formed with an exit port for allowing some blood to escape the reservoir into the inferior vena cava. The exit port reduces the possibility of stagnation in the reservoir. High pressure blood from the aorta temporarily passes through the tubular shunt and into the reservoir, such as during systole. When blood pressure reduces in the aorta, blood from the reservoir passes from the reservoir and through the shunt where it reenters the aorta, such as during diastole.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

The present application relates to the technical field of body position management, in particular to an aorta postoperative patient body position intelligent management pad system based on hemodynamic parameters, which introduces classification and regression tree to organize mean arterial pressure interval, systolic pressure interval, blood pressure change rate sign, exponential weighted deviation interval, cumulative deviation state, uncertainty level and body position maintenance time interval into ordered conditional branches, explicitly injects safety priority logic into body position sorting process, makes high-risk signals obtain higher weight proportion in decision chain, maps body position enumeration into discrete state by limited state machine and introduces interval member guard count and locking time, so that body position switching is no longer instantaneous judgment but triggered after continuous condition satisfaction, and the overall process forms a continuous traceable closed loop under the multi-layer superposition of rule chain, cost weight, state transition and path constraint, the body position execution process remains stability in blood flow fluctuation stage, and nursing operation consistency and controllability are significantly improved.

Systems, devices and methods are provided for supporting cardiac function. A device comprises a catheter having a shaft with a distal end portion configured for advancing through an aortic valve to a left ventricle of a patient and an impeller coupled to the distal end portion of the catheter. One or more inlets are positioned distal of the impeller and coupled to an internal lumen within the catheter to draw blood from the left ventricle through the inlets and into the internal lumen. One or more outlets positioned proximal of the impeller and coupled to the internal lumen to pump the blood through the outlets and into the aorta. The device further includes an extracorporeal motor coupled to a proximal end portion of the catheter and a drive member extending through the catheter shaft and coupling the impeller with the motor to rotate the impeller. The motor may comprise a non-contact motor that generates a magnetic field to rotate the drive member.