204 results about "Aorta" patented technology

A normothermic perfusion circuit can be used to perfuse a donor heart after transportation and before transplantation. The circuit can drain the organ storage container of cold preservation solution, perfuse the aorta of the heart with warm fluid to initiate heart activity, and then perfuse the left atrium of the heart with warm fluid to bolster heart activity and evaluate heart viability. Heart viability can be determined using parameters measured by sensors in the circuit.

A normothermic perfusion circuit can be used to perfuse a donor heart after transportation and before transplantation. The circuit can drain the organ storage container of cold preservation solution, perfuse the aorta of the heart with warm fluid to initiate heart activity, and then perfuse the left atrium of the heart with warm fluid to bolster heart activity and evaluate heart viability. Heart viability can be determined using parameters measured by sensors in the circuit.

An apparatus includes a communication interface and at least one processor. The processor is configured to obtain a size of a lumen in each of a plurality of aortic zones and first information for each of the plurality of aortic zones based on segmentation results of an aorta and the plurality of aortic zones within the aorta; and visualize the size of the true lumen, the first information, and a ratio between the size of the true lumen and the first information in each of the plurality of aortic zones by using a visualization segment corresponding to each of the plurality of aortic zones.

The invention discloses an artificial heart valve near-physiological pulsation fluid external evaluation device and method, and relates to the technical field of heart valve testing.The artificial heart valve near-physiological pulsation fluid external evaluation device comprises a supporting frame, a driving unit, a tested valve installation unit and an artery and peripheral loop unit, the driving unit provides power for liquid flowing, and the tested valve installation unit is used for fixing an artificial heart valve; and a liquid volume assembly and a resistance assembly of the artery and peripheral loop unit can simulate the compliance and resistance of aorta blood vessels and peripheral artery blood vessels, so that the pressure waveform simulation of the systemic circulation loop is more accurate. On the basis of the air cavity, the elastic corrugated pipes with different frequency responses are arranged, the compliance and rebound resilience of the aorta are simulated, a device for rapidly replacing the tested valve is designed, and the mechanical property of the simulated human body aorta is adjusted by adjusting the parameters such as the output frequency and the vibration amplitude of the driving unit; real pressure and flow waveforms under different physiological / pathological conditions are simulated, and a more accurate and convenient detection environment is realized.

The utility model discloses a double-gas-path gas source system and a double-gas-path heart auxiliary system. The double-air-path heart assisting system comprises a pressure generating mechanism which alternately generates positive pressure and negative pressure when working; the first auxiliary device comprises first driven equipment and a first piping pipeline, a pipe body at the farthest end of the first piping pipeline is provided with an inflow channel and an outflow channel, and the first driven equipment is located in the pipe body of the first piping pipeline and corresponds to the outflow channel in position; the second auxiliary device comprises second driven equipment and a second piping pipeline communicated with the second driven equipment; the pressure generating mechanism enables the second driven device to repeatedly expand and contract through the second piping. The detection device is used for acquiring the pressure in the cardiac chamber and the pressure in the aorta; and the control mechanism is used for controlling the pressure generation mechanism to respectively drive the first driven equipment and the second driven equipment according to the corresponding time sequence in a cycle control period according to the pressure signal sent by the detection device.

The invention provides a real-time monitoring and control method and system for pressure in a catheter in breast duct endoscopy, and relates to the technical field of medical equipment monitoring and control, and the method comprises the following steps: forming a multi-dimensional parameter characteristic matrix by collecting temperature, conductivity and image data in the catheter, and carrying out adaptive filtering analysis to extract fluid characteristic parameters; pressure distribution characteristics in the conduit are calculated, fluid flow state parameters are monitored in combination with a microfluid sensor array to identify a local turbulence area, when the turbulence intensity exceeds an early warning threshold value, wavelet transform is adopted to analyze and calculate the turbulence development trend, and the pressure in the conduit is controlled within a safe range through an active pulsation compensation technology; and the safety and the accuracy of breast duct endoscope examination are improved.

The invention provides a self-adaptive control method and device for a double-ventricle auxiliary system. The method comprises the steps that target aortic pressure detected by a first pressure sensor, target left ventricular end diastolic pressure detected by a second pressure sensor, target right atrial pressure detected by a third pressure sensor and target pulmonary artery pressure detected by a fourth pressure sensor are obtained; and determining a strategy for adjusting the left ventricular assist device or the right ventricular assist device according to the target left ventricular end diastolic pressure, the target right ventricular pressure and the target pulmonary arterial pressure when the peripheral perfusion of the target user is insufficient or the lung is over-perfused. The pressure sensors are arranged to detect the pressure of the inlets and the outlets of the left ventricular assist device and the right ventricular assist device, whether adverse events such as peripheral insufficiency or pulmonary hyperperfusion occur to a user or not is judged according to the detected pressure, and then the adverse events are relieved or even solved by adjusting the rotating speeds of the left ventricular assist device and the right ventricular assist device. And the safety of the user is greatly improved.

The utility model relates to a large area contact type thread type degradable magnesium alloy aortic blood vessel anastomat, including the conical inner ring, conical outer ring and sleeve outer ring that set gradually from inside to outside, be provided with blood vessel clamping space between the conical inner ring and conical outer ring, it is the thread cooperation between conical outer ring and sleeve outer ring, adjust the size of blood vessel clamping space through the rotation sleeve outer ring, sleeve outer ring. The utility model simple structure, reasonable in design, convenient to use, adjust the size of blood vessel clamping space through the rotation conical outer ring and sleeve outer ring to fixed blood vessel, realize blood vessel anastomosis fast, avoid the mode of the traditional everted type through end face combination simultaneously, greatly increase the contact area between blood vessel and prevent the occurrence of blood leakage.

The invention discloses application of gynostemma pentaphyllum polysaccharide to prevention of vascular wall thickening caused by space microgravity and a medicine, the gynostemma pentaphyllum polysaccharide is applied to prevention of vascular wall thickening caused by space microgravity and the medicine for prevention of vascular wall thickening caused by space microgravity, and the medicine contains the gynostemma pentaphyllum polysaccharide; the gynostemma pentaphyllum polysaccharide reduces thickening of blood vessel walls by inhibiting proliferation and migration of vascular smooth muscle cells, can be used for preventing or treating aorta blood vessel wall thickening caused by space microgravity, and is suitable for health guarantee of astronauts in long-term space missions.

Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.

A delivery system for delivering a prosthetic valve in a compressed condition over an inner shaft of a catheter. The delivery system includes a tip extending distally from the inner shaft. The tip has a proximal section and an opposite distal section extending to an end of the tip. The proximal section is configured to support an end of the prosthetic valve during loading and delivery of the prosthetic heart valve and includes a first portion, a second portion, and a third portion. The first portion is adjacent the distal section. The second portion is between the first portion and third portion. The third portion is adjacent a proximal end of the tip. An outer diameter of the first portion is greater than an outer diameter of the inner shaft, an outer diameter of the second portion, and an outer diameter of the third portion.

The invention discloses a staged pump speed regulation and control implementation method for improving VA-ECMO cycle stability, and relates to the technical field of biomedical engineering. The method comprises the following steps: acquiring a real-time aorta pressure waveform, a peripheral artery pressure waveform and an ECMO post-pump pressure waveform of a patient, and extracting pulse wave characteristics, a pressure oscillation amplitude and phase deviation information; calculating a heart-ECMO blood flow intersection collision intensity index and evaluating a heart load state grade; acquiring a vascular compliance estimated value of a patient, and determining a target pump speed adjusting mode and adjusting amplitude according to a hierarchical regulation strategy library; and the current actual pump speed is obtained, a speed regulation decision is made, the ECMO pump is driven to execute graded stepped pump speed regulation, and the regulation speed is dynamically corrected in real time in the regulation process until the cyclic stable interval is reached. Quantitative evaluation and self-adaptive regulation and control of the pump speed are achieved, hemodynamic fluctuation is inhibited, and the stability and safety of VA-ECMO cycle support are improved.

The invention provides a ventricular elasticity value estimation method and device.The method comprises the steps that a first parameter and a second parameter are obtained, the first parameter comprises at least one of target ventricular pressure, target aortic pressure and target pulmonary arterial pressure of a target user, and the second parameter comprises at least one of the target ventricular pressure, the target aortic pressure and the target pulmonary arterial pressure; the second parameter comprises the pumping flow of the target ventricular assist device and the cardiac cycle of the target user; inputting the first parameter and the second parameter into a target decision model, and outputting a target ventricular volume; and estimating a target ventricular elasticity value according to the ratio of the target ventricular pressure to the target ventricular volume. The ventricular volume of the current user is estimated through the decision model, the estimated ventricular elasticity value is calculated according to the ratio of the ventricular pressure to the ventricular volume, and the ventricular elasticity value of the patient can be accurately predicted in real time without depending on ultrasonic equipment.

The invention belongs to the technical field of biological medicine, and particularly provides application of flufenidone in preparation of a medicine for preventing or treating left heart failure. The research finds that the flufenidone has the effects of relieving myocardial cell hypertrophy under a heart failure cell model and relieving myocardial hypertrophy, fibrosis and heart function deterioration of an aortic constriction animal model. According to the present invention, further research results show that fluorofenidone is directly combined with SERCA2a through Q758, D812 and E917 residues of SERCA2a so as to inhibit recognition, combination and polyubiquitination effects of WWP1 on SERCA2a, such that the protein level and the activity of SERCA2a are stabilized so as to achieve the chronic left heart failure treatment purpose. Therefore, the flufenidone serving as an active ingredient has good application prospect and application value in research and development of novel medicines for treating chronic left heart failure.

This application relates to a blood pump, comprising a primary pumping device, a first catheter, a secondary pumping device, and a second catheter connected in sequence. The primary pumping device has a first inlet and a first outlet, and the secondary pumping device has a second inlet and a second outlet. The secondary pumping device includes a secondary cannula, which has a proximal end, a distal end, and an enlarged portion. The proximal end is adjacent to the second catheter and has a second outlet. The distal end is connected to the first catheter and has a second inlet. The two ends of the enlarged portion are smoothly transitioned to the proximal end and the distal end, respectively. This blood pump increases the blood volume pumped by the secondary pumping device, allowing most of the blood in the aorta to be accelerated by the secondary pumping device, thus significantly improving the pumping efficiency of the secondary pumping device.

The invention relates to the technical field of medical instruments, and particularly discloses a catheter handle, a catheter pump and a catheter pump system. According to the catheter handle, the perfusion liquid inflow connector, the artery pressure measuring liquid inlet connector, the artery pressure measuring liquid outlet connector and the catheter connector are arranged on the perfusion support, the perfusion liquid outflow connector is arranged on the coupling support, the perfusion support and the coupling support are large in size, and therefore the connectors can be conveniently arranged; the number of parts is reduced, so that the machining process of the guide pipe device is simplified; besides, the artery pressure measuring liquid inlet connector and the artery pressure measuring liquid outlet connector are arranged on the perfusion stent, the connectors can be conveniently arranged, an independent aorta pressure sensing channel is formed, and compared with the prior art, flowing of perfusion liquid used for sensing the aorta pressure is not prone to being interfered by other factors, and the perfusate can be used for sensing the aorta pressure. And thus, the aortic pressure sensing precision is improved.

The application discloses an auxiliary instrument for aortic replacement artificial blood vessel surgery, which comprises a collapsible and inflatable bag body which extends into the aorta of a heart to block blood, wherein the bag body is provided with a bag body channel for blood to pass through, and the upper end of the bag body is connected with a drainage tube; the connection end of the drainage tube with the bag body is provided with a drainage tube cavity; the outer side of the drainage tube is provided with a drainage tube through hole for guiding the seepage blood between the bag body and the aorta of the heart into the drainage tube cavity; the drainage tube is respectively provided with a drainage tube channel which is communicated with the bag body channel and is used for sending the blood in the aorta of the heart into an extracorporeal circulation device, an injection channel which is used for injecting or extracting liquid or gas to the bag body so as to make the bag body inflate or shrink, and a seepage blood extraction channel which is used for extracting the seepage blood in the drainage tube cavity; the seepage blood is guided into the drainage tube cavity through the drainage tube through hole, and the seepage blood is extracted through the seepage blood extraction channel, so that the problem of the seepage blood blocking the suture visual field is solved.

The application provides a rotating type artificial mechanical heart valve, and belongs to the technical field of heart valves, and comprises: a valve ring; a valve leaflet group, which is rotationally arranged in the valve ring; when the valve leaflet group is in an open state, a spiral channel is formed in the valve ring; and when the valve leaflet group is in a closed state, the valve leaflet group limits blood flow through the valve ring; the rotating type artificial mechanical heart valve of the application forms a spiral channel with the same rotation direction as the blood rotation flow state when the valve leaflet group is in the open state; the spiral channel is arranged to effectively rotate the blood flow, generate corresponding spiral flow state, and the rotation of the outlet blood flow is beneficial to the full flow and development of the blood flow in the aorta, reduces the turbulence, stagnation area and damage to the normal rotation flow state in the aorta, and the heart valve provided by the application has excellent hemodynamic characteristics and can effectively inhibit the aortic dilation complication caused by aortic valve replacement.

The invention relates to a guide-wire-free integrated balloon catheter system, which comprises a balloon dilatation mechanism, a balloon catheter and a balloon catheter, the balloon dilatation mechanism comprises a first balloon, a second balloon and a balloon pushing rod, and the first balloon and the balloon pushing rod are arranged in a penetrating manner; the first balloon is used for blocking the aorta I region; the second balloon and the balloon pushing rod are arranged in a penetrating manner; the second balloon is used for blocking the aorta III region; a first outlet and a second outlet are respectively formed in the balloon pushing rod between the first balloon and the second balloon and in the other side of the second balloon, and a blood inlet is further formed in the other side of the first balloon; the blood inlet is communicated with the first outlet and the second outlet through a pipeline and is closed or opened through a valve, and the pipeline is located in the balloon pushing rod. The balloon is used for improving the hemostasis and plugging effects, meanwhile, avascular necrosis of internal organs and limbs below the plugging position can be prevented, the balloon can better play the hemostasis, plugging and other roles, and the hemostasis time is prolonged.

An occlusion assembly for occluding the aorta of a patient is presented. The occlusion assembly includes an elongate shaft of two separate extrusions to which an elastomeric balloon envelope is bonded to an end of each. A support wire extends through the elongates shaft and the balloon envelope. At a distal end of the shaft, the support wire is provided with an atraumatic J-tip. At the proximal end of the shaft the proximal end of the support wire is secured to a proximal hub to give the entire assembly sufficient stiffness to be advanced into the vasculature of the patient. The balloon envelope is pre-molded to have a reverse teardrop or “ice cream cone” like shape and will maintain that general shape throughout inflation to the fully inflated state. If the balloon envelope is over inflated, the balloon envelope will advance distally and proximally (lengthening) along the support wire without damage to the surrounding vessel.

A neurovascular catheter for delivery through an aorta and into an ostium can include a tubular body between a proximal end to a distal end. The tubular body can have a length of 140 cm to 180 cm, a 5Fr size, and an internal diameter of about 0.065" to about 0.067". The tubular body can include a proximal portion and a distal portion. The distal portion can include a polymer layer and a layer of braids. The proximal portion can include a hypotube and the layer of braids.

The invention discloses a perfusion type kidney aorta blocking balloon assembly which comprises a balloon, one end of the balloon is communicated with one end of a communicating pipe, an injection pipe is arranged on the inner side of the balloon, the end of the injection pipe extends to the outer side of the balloon, and the ends, away from the balloon, of the injection pipe and the communicating pipe are each provided with a connector. The waterproof piece is slidably arranged outside the communicating pipe in a sleeving mode and comprises a water blocking cover and an adsorption cover, and the water blocking cover and the adsorption cover are arranged outside the communicating pipe in a sleeving mode and can slide along the outer wall of the communicating pipe; the water blocking cover is closer to the balloon than the adsorption cover, and the adsorption piece is used for adsorbing the adsorption cover to the skin surface of a patient. According to the blocking balloon assembly, when a surgical puncture hole for minimally invasive surgery and communicating pipe infusion is exposed, condensed water drops are isolated through the movable waterproof piece, the adsorption cover is tightly attached to the skin through the adsorption piece, the puncture hole is prevented from being polluted by the water drops, and air exposure of a wound is reduced; therefore, the infection probability is reduced and the surgical operation safety is improved.

The invention discloses a method for blood vessel segmentation, feature value extraction and data integration based on V-net, and relates to the technical field of medical image analysis. Comprising the steps that S1, a CT image of a patient is acquired and preprocessed; s2, constructing and training a V-net neural network, inputting the preprocessed CT image into the trained V-net neural network, and reconstructing a blood vessel model; s3, feature value extraction is carried out on the blood vessel model. By constructing and training the V-net neural network, the blood vessels in the patient's abdomen CT medical image are segmented and reconstructed to obtain portal vein, hepatic artery, aorta and other blood vessel models with good segmentation effects, and feature values of the blood vessel models are extracted and data are standardized through an algorithm, so that the accuracy of the blood vessel models is improved. Therefore, the CT image information can show the blood vessel form and the characteristic value in a model and datamation form, and the concerned blood vessel characteristic information can be obtained from the complex CT image.

The invention belongs to the technical field of medical instruments, and particularly relates to an aorta balloon counterpulsation catheter which comprises a catheter body, one end of the catheter body is fixedly connected with a connector, the catheter body is sleeved with a balloon body in the axial direction, the catheter body is sleeved with a cylinder, and the connector is provided with a positioning mechanism used for positioning the position of the cylinder. A square frame is fixedly arranged at the top of the cylinder, a sliding block is arranged in the square frame in a penetrating mode, an adjusting mechanism used for adjusting the position of the sliding block is arranged in the square frame, and a cutting knife is fixedly arranged at the bottom of the sliding block. According to the aortic balloon counterpulsation catheter, the catheter body can be conveniently damaged through the cutting knife and the protruding block, secondary recycling of the aortic balloon counterpulsation catheter can be effectively avoided, and in order to avoid secondary utilization after recycling, the position of the cutting knife is adjusted, the catheter body is punctured, and the catheter body is pulled to move; when the catheter body is cut, the cutting knife can cut the catheter body in the axial direction, and then the catheter body can be damaged.

A stent graft for treating an arterial aneurysm includes loops fixed to struts of stents, wherein the struts define distal and proximal apices. The ends of a ligature can be linked by a wire in a stent graft delivery system that threads anchor loops longitudinally spanning ends of the ligature to maintain the stent in a radially constricted position during delivery to the aneurysm. A delivery system and method for implanting a stent graft prosthesis includes and employs a torque component at a distal end of the stent graft prosthesis, whereby following advancement of the stent graft to a surgical site in a constrained or partially constrained configuration, torque is applied to the torque component to rotationally align the stent graft about a longitudinal axis of the stent graft, followed by deployment of the stent graft in correct rotational alignment. A delivery system and method of its use includes an apex capture assembly, a leg clasp, and a leg stop for capturing a stent graft during orientation and stabilization at an implantation site of a surgical site.

The transcatheter aorta balloon blocking device comprises a balloon catheter, a balloon is arranged at the end of the balloon catheter, a balloon Y-shaped connecting piece is arranged at the tail end of the balloon catheter in a communicating mode, and fixing openings matched with the balloon catheter are formed in the upper end and the lower end of the balloon. Flexible protrusions are symmetrically formed at the upper end and the lower end of the balloon, and the whole flexible protrusions are of a mastoid structure and annularly distributed on the outer side face of the balloon catheter. The balloon, the flexible protrusions, the top face and the bottom face are arranged, the flexible protrusions are obliquely distributed towards the end of the balloon as a whole, so that the flexible protrusions abut against the blood vessel wall at a specific angle, the blood vessel wall and transverse external force generate a confrontation angle, and the two ends of the balloon are limited and fixed through cooperation of the two sets of flexible protrusions; the balloon is prevented from further moving forwards or backwards, so that the whole balloon is effectively prevented from displacing after being fixed, and the safety of the device is further improved.

A method for performing a robotic-assisted orthotopic heart transplant includes forming a working port subareolarly by a mini-thoracotomy at a working intercostal space, forming additional ports for robotic arms, and arranging robotic arms through the ports. A first robotic arm with first forceps extends through a second port lateral to a mid-clavicular line, while second and third robotic arms containing an imaging device and second forceps operate through the working port. A fourth robotic arm with scissors or needle holder extends through a third port proximal to an anterior axillary line. The method includes cannulating for cardiopulmonary bypass, opening the pericardium, cross-clamping the aorta, removing the native heart, and performing sequential anastomoses of the donor heart including the left atrium, pulmonary artery, aorta, inferior vena cava, and superior vena cava.

A physical treatment device for rehabilitation of an old cardia-cerebrovascular disease patient belongs to the technical field of physical treatment instruments and comprises a bed body, an electrocardiogram monitor is arranged on one side of the bed body, a mattress is placed at the top of the bed body and comprises a first supporting pad and a second supporting pad, and the first supporting pad and the second supporting pad are hinged through a rotating shaft at the joint. The second supporting pad is provided with a physical treatment assembly used for assisting the elderly patient in rehabilitation treatment, through cooperation with the cardiac cycle of the patient, in the diastolic period, the driving motor is meshed with the synchronous rack through an incomplete gear, the air bag is sequentially inflated from the far end of the limb to the near end of the limb, blood vessels are pressed, and blood is driven back to the aorta; important blood vessel perfusion is added, myocardial ischemia and other symptoms are relieved, the device automatically exhausts air after the diastolic period ends, it is ensured that blood smoothly flows to the lower limbs, meanwhile, the whole device is combined with a bed body, and good rehabilitation treatment exercise can be achieved for paralyzed and disabled patients.

The invention discloses an IVUS-based guide wire-free blood vessel center line identification and navigation method, and relates to the technical field of blood vessel intervention and image navigation. The method comprises the following steps: arranging an IVUS transducer at the front end of an instrument, and synchronously obtaining an IVUS frame sequence and a probe pose; through cavity wall segmentation, center point extraction and time sequence-space fusion processing, a three-dimensional center line of the main blood vessel is constructed, and a safety envelope is generated; for a branch artery, branch super-selection navigation is realized through candidate sector detection, direction estimation and center line generation and splicing; meanwhile, a mismatch rollback and failure protection mechanism is set, so that navigation safety is ensured; the virtual center line is used for replacing a solid guide wire, the risk that blood vessels are punctured and mistakenly enter a false cavity is reduced, the radiography frequency and radiation exposure are reduced, the operation time is shortened, and the method is suitable for complex intracavity treatment scenes of aorta trunks and branches.