43 results about "Heart wall" patented technology

A sequence of images acquired consecutively in time at fixed time intervals is received, the images comprising image data of at least part of a heart having a heart wall, identifying, in each image, at least part of the heart wall and defining, in each image, at least one vector point on the identified heart wall. The method further comprises determining motion of the vector point over time, based on the sequence and receiving a first reference related to the heart. Based on the tracking of the vector point and the first reference, a motion vector is determined indicating motion of the vector point relative to the reference.

A system is provided for generating and displaying a sequence of three-dimensional (3D) graphics that illustrate motion of the heart over a cardiac cycle. The system generates a start heart wall mesh and an end heart wall mesh that represent a start geometry and an end geometry of a heart wall derived from a start 3D image and an end 3D image. The system then generates one or more an intermediate heart wall 3D meshes based on an intermediate geometry of the heart wall. An intermediate geometry is interpolated based on the start geometry and the end geometry factoring a start time of a start heart wall mesh, an end time of the end heart wall mesh, and an intermediate time for the intermediate heart wall mesh. The system then displays in sequence representations the heart wall 3D meshes to illustrate the motion.

A method for localizing the source of an arrhythmia within a heart wall is disclosed. The method involves accessing an indication of the source location of the arrhythmia within the endocardium. A normal vector is generated that is normal to the endocardium at the source location in the direction of the epicardium layer. An activation vector indicating the direction of electrical force of the heart during an initial stage of depolarization is determined. The depth angle between the normal vector and the activation vector is determined, and the depth of the source location within the heart wall is indicated based on a depth angle.

An implantable lead configured to be implanted in an anterior mediastinum of a patient. The implantable lead includes a generator interface and a lead body coupled to the generator interface. The generator interface is configured to couple the implantable lead to a generator of an implantable treatment device. The lead body includes a sternal portion configured to be positioned in the anterior mediastinum to engage a posterior portion of a sternum of the patient, and a heart wall portion configured to be positioned in the anterior mediastinum to engage a heart wall of a heart of the patient. At least one of the sternal portion or the heart wall portion is configured to deliver treatment energy to the heart of the patient.

Valvular implants and blood vessel closure devices herein are configured to be positioned in the heart and to block regurgitant blood flow from the heart into blood vessels supplying blood to the heart. The valvular implants can have a cover, a membrane, a valve, a resilient frame, and / or other features. Some valvular implants can have anchors to be positioned in the blood vessels, such as in pulmonary veins, and can anchor the implant to the heart wall. Various embodiments of covers and / or membranes act as valves contracting and expanding, to alternately permit and block blood flow. The valvular implants can cover one or more blood vessels, such as one, two, three, or four pulmonary veins, and can also be configured and implanted to block an appendage to the heart, such as the left atrial appendage.

An introducer sheath for use in hybrid procedures on the heart includes a shaft having a distal balloon which is inflated inside the heart wall. A proximal collar is slidable along the shaft and locked to anchor the sheath to the wall of the heart. The sheath has markings visible to both the naked eye and under fluoroscopy to aid in judging the depth of insertion.

Disclosed are devices, systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various located within the associated chamber of the heart. To create a database of dipole densities, mapping information recorded by multiple electrodes located on one or more catheters and anatomical information is used. In addition, skin electrodes may be implemented. Additionally, one or more ultrasound elements are provided, such as on a clamp assembly or integral to a mapping electrode, to produce real time images of device components and surrounding structures.

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient An anchor for engaging a papillary muscle or heart wall is described, wherein the anchor is movable between a delivery configuration and a deployed configuration. When the anchor is in the delivery configuration the anchor has a first outer dimension and when the anchor is in the deployed configuration the anchor has a second outer dimension. The first outer dimension is smaller than the second outer dimension. The anchor is engageable with a papillary muscle or a heart wall when the anchor is in the deployed configuration. The anchor comprises a plurality of arms coupled at a proximal end thereof to a body portion, at least one arm of the plurality of arms movable between a first position and a second position when the anchor moves from the delivery configuration to the deployed configuration. The plurality of arms each have a distal tip for engaging the papillary muscle or heart wall, wherein as the anchor is moved from the delivery configuration to the deployed configuration, the plurality of arms are movable from an elongated shape to a curved shape.

A cardiac electrode assembly. The inventive electrode assembly includes an active fixation device, such as a helical electrode configured to screw into the myocardium or a vessel wall. The invention also includes an array of two or more reversed tines. The reverse tines bear against the heart wall or vessel wall and inhibit unwanted distal motion of the electrode assembly. Various deployment devices that aid in the installation of the inventive electrode assembly are also described.

A method of estimating a value associated with heart wall tension. The method comprises: using motion data recorded with a sensor in communication with the heart to identify motion in the heart; and estimating a value associated with heart wall tension based on the identified motion in the heart. The motion in the heart that forms the basis of the estimation may be a vibration in the heart wall. A heat monitoring system for carrying out the method of estimating a value associated with heart wall tension comprises a sensor configured to be placed in communication with the heart in order to identify motion in the heart; and a data processing device arranged to receive motion data from the sensor and to then carry out the steps of the method.

The present invention provides a system and method for navigating within the heart and attaching to the heart wall to perform injection of one or more agents into tissue. The system includes an outer catheter, an intermediate catheter slidably disposed within the lumen of the outer catheter, and a needle catheter slidably disposed within the lumen of the intermediate catheter. The intermediate catheter includes a vacuum hood attached to the distal end of the intermediate catheter so that the radiopaque distal tip of the intermediate catheter extends into the vacuum hood. The vacuum hood includes at least two radiopaque features, and the spatial relationship of the radiopaque features is visually changed under fluoroscopy when the vacuum hood is under a sealed vacuum.

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient. A system for adjusting tension in an artificial chordae tendineae comprises a clip engageable with a leaflet of a heart valve. The system further comprises an anchor engageable with a papillary muscle or heart wall and an artificial chordae tendineae movable in a first direction and a second direction and coupleable between the clip and the anchor. The anchor includes a body portion and a locking portion comprising a housing portion configured to receive therein a portion of the artificial chordae tendineae. The locking portion is engageable with the artificial chordae tendineae and moveable between an unlocked configuration and a locked configuration, wherein in the unlocked configuration the locking portion is configured to allow movement of the artificial chordae tendineae and wherein in the locked configuration the locking portion is configured to prevent movement of the artificial chordae tendineae, An actuator is coupleable to the locking portion, where the actuator is configured to move the locking portion between the unlocked and locked configuration.

A system may display a graphic of a heart that provides an indication of a target zone and an avoidance zone for implantation of the lead. The system may identify a location of the lead based on the location electrocardiogram, display on the graphic an indication of identified location; and determine whether the identified location is at an appropriate implantation site based on the location electrocardiogram. The system may, when the identified location is an appropriate implantation site, output an indication that the lead is at an appropriate implantation site. The system may, for each of one or more of tunneling electrocardiograms, determine whether the lead is at an effective position within the heart wall based on the tunneling electrocardiogram; and when the lead is at an effective position, output an indication that the lead is at an effective position.

An anchor assembly is configured to implant a cardiac anchor into a heart wall of a patient to anchor a suture configured to extend from a valve leaflet of the heart as an artificial chordae. The anchor assembly can include an anchor hub defining an open interior and a helical coil extending distally from the anchor hub and having a sharpened tip configured to embed the helical coil into the heart wall upon rotation of the helical coil. A spring can be disposed within the open interior of the anchor hub. Compressing the spring distally can create an open space within the open interior of the anchor hub for a suture extending through the anchor hub to slide freely and releasing compression on the spring can cause the spring to expand in a proximal direction to clamp the suture within the open interior of the anchor hub.

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient. A system for adjusting tension in an artificial chordae tendineae includes an artificial chordae tendineae coupleable between a clip and an anchor. The clip is engageable with a leaflet of a heart valve while the anchor is engageable with a papillary muscle or heart wall. The anchor includes a body portion, and a locking portion coupleable with the artificial chordae tendineae and configured to allow movement of the artificial chordae tendineae in a first direction while preventing movement of the artificial chordae tendineae in a second direction opposite the first direction. An actuator is coupled to the locking portion for selectively releasing the locking portion to enable selective movement of the artificial chordae tendineae in the second direction.

The present invention relates generally to the field of medical devices for delivering artificial chordae tendinae in a patient. A system for adjusting tension in an artificial chordae tendinae includes an artificial chordae tendinae couplable between a clip and an anchor. The clip is engageable with a leaflet of a heart valve and the anchor is engageable with a papillary muscle or heart wall. The anchor includes a body portion and a locking portion couplable with the artificial chordae tendinae and configured to allow movement of the artificial chordae tendinae in a first direction while preventing movement of the artificial chordae tendinae in a second direction opposite the first direction. An actuator is coupled to the locking portion to selectively release the locking portion to enable selective movement of the artificial chordae tendinae in the second direction.

A cardiac lead system is provided. The lead is placed epicardially through the transverse pericardial sinus with integrated curvatures to prevent the lead from slipping out of the transverse pericardial sinus. Interaction with multiple chambers of the heart is facilitated in a single lead, without anchors that embed into the heart wall. Multiple electrodes can be grouped over each targeted heart area to ensure adequate electrical contact.

A method for localizing the source of an arrhythmia within a heart wall is disclosed. The method involves accessing an indication of the source location of the arrhythmia within the endocardium. A normal vector is generated that is normal to the endocardium at the source location in the direction of the epicardium layer. An activation vector indicating the direction of electrical force of the heart during an initial stage of depolarization is determined. The depth angle between the normal vector and the activation vector is determined, and the depth of the source location within the heart wall is indicated based on a depth angle.

Puffin heart wall hanging

The application discloses a duck hepatitis virus 1 type DHAV-1 / HNSQ and application thereof, and belongs to the field of animal virology and genetic engineering. The duck hepatitis virus 1 type DHAV-1 / HNSQ has been preserved in the China Center for Type Culture Collection on March 5, 2026, and the preservation number is CCTCC NO:V202622. The VP1 gene of the variant strain has a deletion of three consecutive nucleotides. Animal experiments show that, after the variant strain infects ducklings, in addition to causing typical duck viral hepatitis lesions, the variant strain can also stably cause a new phenotype, such as thinning of the heart wall, reduction of myocardial toughness and liquefaction necrosis of pancreatic tissue, which has never been reported in the prior art, thereby providing important biological materials for effective prevention and control of duck hepatitis and pathogenic mechanism research.

The invention discloses a transapical implantation system of a heart auxiliary pressure pump, relates to the technical field of medical instruments, can solve the problems that the heart wall needs to be cut, the operation process is troublesome and the risk is high when an existing heart auxiliary pressure pump is implanted, and can effectively reduce the implantation difficulty of a pump body assembly compared with the prior art. The embodiment of the invention discloses a transapical implantation system of a heart auxiliary pressure pump, which comprises an outer tube, an inner push tube and a pump body assembly, and the pump body assembly comprises a pump body main body, a turnover paddle structure and a plurality of locking hooks movably connected to the peripheral wall of the pump body main body along the circumferential direction of the pump body main body; bent embedded sections are arranged at the ends, away from the pump body, of the locking hooks, and the bent embedded sections of the multiple locking hooks are all bent clockwise or anticlockwise; a first rotation limiting structure is further arranged on the peripheral wall of the pump body main body, a second rotation limiting structure is arranged at the end of the inner pushing pipe, and the pump body assembly and the inner pushing pipe synchronously rotate along with the first rotation limiting structure and the second rotation limiting structure which are matched with each other.

An apparatus for at least partially restoring regurgitation in a heart valve includes at least one subvalvular device including a subvalvular portion defining a longitudinal axis and positioned proximate a subvalvular heart wall adjacent a heart valve. An anchor portion is adjacent to and longitudinally spaced from the subvalvular portion. A connector neck is longitudinally inserted between and attached to the subvalvular portion and the anchor portion. The connector neck longitudinally penetrates a base of the first valve leaflet and at least one of the annulus of the heart valve at a created puncture site. A fastener is selectively connected to the at least one subvalvular device. The fastener penetrates at least one of the first valve leaflet and the second valve leaflet to hold the at least one leaflet in place relative to the at least one subvalvular device.

The application provides a heart wall thickness monitoring device, which comprises a medical catheter in direct contact with a heart wall, an impedance measuring instrument and a computing processing device storing a calibration matrix, wherein the medical catheter is used for generating an electric signal and measuring a contact pressure value of the medical catheter in direct contact with the heart wall; the impedance measuring instrument is electrically connected with the medical catheter and is used for converting the electric signal into an impedance value; the computing processing device is electrically connected with the medical catheter and the impedance measuring instrument, receives the contact pressure value and the impedance value, and finds a data group closest to the contact pressure value and the impedance value in the calibration matrix, and the heart wall thickness in the data group is the monitored heart wall thickness. The application realizes the problem of low-cost real-time monitoring of the tissue thickness of a target ablation site in an ablation operation process, and based on the real-time monitored tissue thickness, the ablation energy and the ablation duration of the medical catheter in the ablation process can be determined, so that the operation safety and the ablation treatment effect are improved.

The application discloses a trans-apical implantation system of a heart auxiliary pressurizing pump and relates to the technical field of medical devices, which can solve the problem that the existing heart auxiliary pressurizing pump implantation needs to cut open the heart wall, the surgical process is troublesome, and the risk is high, and can effectively reduce the implantation difficulty of the pump body assembly compared with the prior art. The trans-apical implantation system of the heart auxiliary pressurizing pump comprises an outer tube, an inner push tube, a pump body assembly, the pump body assembly comprises a pump body main body and a reversible paddle structure, and a plurality of locking hooks are movably connected to the outer peripheral wall of the pump body main body in the circumferential direction; the end, away from the pump body main body, of the locking hook is provided with a bent embedding section, and the bent embedding sections of the plurality of locking hooks are all bent in the clockwise direction or the counterclockwise direction; the outer peripheral wall of the pump body main body is further provided with a first rotation limiting structure, the end of the inner push tube is provided with a second rotation limiting structure, and the pump body assembly and the inner push tube are synchronously rotated through the mutually matched first rotation limiting structure and the second rotation limiting structure.

The invention discloses a core-wall rockfill dam parameterization driving three-dimensional design method based on a 3DE platform. The method comprises the steps that firstly, an original terrain model is imported into a 3DE system (or the original terrain model is created in the 3DE system); 2, selecting a damming position based on the original terrain model, and creating a dam axis; thirdly, a core-wall rock-fill dam parameterized large formwork is adjusted and used, and an initialized core-wall rock-fill dam model is established; and 4, the parameterization of the initialized core-wall rock-fill dam model is verified, and the corrected core-wall rock-fill dam model is obtained. And 5, based on the corrected core-wall rockfill dam model, carrying out design scheme comparison and optimization to obtain a final core-wall rockfill dam design scheme, and outputting the core-wall rockfill dam engineering quantity. The invention specifically provides a set of systematic and complete core-wall rock-fill dam three-dimensional design method, the design process and steps are implanted into a core-wall rock-fill dam three-dimensional parameterized model, the three-dimensional model is updated through full parameterization driving with design parameters as the core, and the design work of the core-wall rock-fill dam is completed.

Described here are wireless monitoring devices, systems, and methods for estimating one or more physiological parameters of a patient. These devices and systems may measure or receive a signal waveform transmitted through one or more of fluid and a physiological structure of a patient. This measured signal waveform may be processed to generate waveform parameter data used to estimate a physiological parameter such as blood velocity, heart wall thickness, and the like.

Ablation device including a probe structure 10 having a proximal end 12 and a distal end 14. Probe structure 10 includes a tubular first catheter 16, a tubular second catheter 18 surrounding the first catheter and a tubular guide catheter extending within the first catheter 16. The first catheter 16 carries a cylindrical ultrasonic transducer 20 adjacent its distal end. The transducer 20 is connected to a source of electrical excitation. The ultrasonic waves emitted by the transducer 20 are directed at the heart wall tissue. Once the tissue reaches the target temperature, the electrical excitation is turned on and off to maintain the tissue at the largest temperature. Alternatively, the transducer 20 is subjected to continuous excitation at one power level and upon the tissue reaching the target temperature, the power level of the continuous excitation is switched to a second lower power level.

A method for localizing the source of an arrhythmia within a heart wall is disclosed. The method involves accessing an indication of the source location of the arrhythmia within the endocardium. A normal vector is generated that is normal to the endocardium at the source location in the direction of the epicardium layer. An activation vector indicating the direction of electrical force of the heart during an initial stage of depolarization is determined. The depth angle between the normal vector and the activation vector is determined, and the depth of the source location within the heart wall is indicated based on a depth angle.