738results about "Annuloplasty rings" patented technology

A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

The application relates to the field of medical devices, in particular to a repair system capable of accurate positioning, which comprises a delivery catheter, a positioning support arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guide wire, the positioning support is arranged at the distal end of the delivery catheter, the positioning support is provided with a plurality of anchoring points distributed in the circumferential direction, the flexible sleeve is provided with a plurality of connecting points arranged in correspondence with the anchoring points, the guide wire passes through the connecting points and the anchoring points corresponding to the connecting points in sequence, and after the positioning support is released, the anchoring mechanism pushes the flexible sleeve, so that the flexible sleeve cooperates with the guide wire and guides the anchoring mechanism to reach each anchoring point along a predetermined route and complete anchoring; the application not only simplifies the structure of the device, but also realizes accurate guidance.

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

The present invention discloses a prosthetic heart valve comprising at least two valve components, a sealant covering the valve components, and an edge-sealing structure. A space is formed between the valve components covered with the sealant. The edge-sealing structure has a closed end face and connects the ends of the sealant to form a closed space within the space. The prosthetic heart valve provided by the present invention can reduce the risk of thrombosis between the valve components. Because the edge-sealing structure is flexible, it has little effect on the compression and gripping of the prosthetic valve, and the addition of the edge-sealing structure does not affect the normal function of the prosthetic valve.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

The present application relates to the field of medical devices, and specifically to a repair device for preventing valve regurgitation, comprising a mounting bracket, a single anti-reflux prosthesis for replacing the function of a single native valve leaflet, and a fixing member, wherein one end of the single anti-reflux prosthesis is fixed on the mounting bracket, and an atrial segment is provided at the distal end of the mounting bracket, and the atrial segment is configured to adapt to the morphology of the native valve ring tissue, and the atrial segment includes a leak-proof portion, and the proximal end portion of the mounting bracket is anchored in the ventricle by the fixing member, wherein, after the mounting bracket is installed in place, the leak-proof portion abuts against or fits the native valve ring tissue, and when the native valve opens and closes so that the morphology of the native valve ring changes, the leak-proof portion follows the morphological change of the native valve ring and produces adaptive deformation, so that the leak-proof portion always abuts against or fits the native valve ring tissue.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

The present application relates to the field of medical devices, and in particular to a guideable positioning anchoring system, comprising a delivery catheter, a positioning bracket arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guiding mechanism, wherein the positioning bracket is arranged at the distal end of the delivery catheter, and the positioning bracket is provided with a plurality of anchoring points distributed along the circumferential direction, the flexible sleeve is provided with a plurality of connection sites, and the guiding mechanism comprises a plurality of guide wires, which respectively pass through the connection sites and are connected with the anchoring points, wherein the distal end portion of the anchoring mechanism is sleeved in the flexible sleeve, and the flexible sleeve cooperates with the guide wire so that the anchoring mechanism can be guided to each anchoring point along a predetermined route and complete anchoring; the anchoring mechanism in the present invention can be guided to each anchoring point along a predetermined route and complete anchoring, without the need to repeatedly search for the position through images, and the operation is convenient and the accuracy is high.

Prosthetic ring valve assemblies are disclosed. A prosthetic valve ring assembly includes an outer tube and a plurality of anchors. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the prosthetic valve ring assembly to annulus tissue of a patient.

A heart valve prosthesis comprising a radially expandable and compressible annular frame is disclosed. The frame comprises a plurality of interconnected rows of cells disposed between an inflow end and an outflow end of the frame, the interconnected rows of cells comprising a plurality of outflow struts defining the outflow end and a plurality of inflow struts defining the inflow end. The frame further comprises a plurality of tip regions formed at the inflow end and the outflow end, each tip region curved between two angled strut portions and forming one of the outflow struts or one of the inflow struts with the two angled strut portions.Each tip region has a reduced width and a length extending at least 25% of the total length of the outflow strut or the inflow strut, the reduced width being less than the width of the two angled strut sections.

Various examples are provided related to a cardiac valve repair device. In one example, the device includes an outer structure with outer blocks, and inner blocks. Each outer block can include an outer magnet pack disposed within in outer block void, at least one tension wire channel extending through the outer block between a first end and a second end and along the outer block void, a connection point on each of the first end and the second end, and attachment openings on each of a first side and a second side extending between the first end and the second end. The outer structure can also include tension wires extending through corresponding tension wire channels and connectors that can couple the outer blocks. Each inner block includes an inner magnet pack disposed within an inner block void and attachment openings that correspond to the attachment openings of the outer blocks.

A system comprises a series of anchors, an anchor-storage device, and an anchor driver that is slidably coupled to the anchor-storage device. The anchor-storage device comprises a spring, and a housing, shaped to define: (i) a loading site, and (ii) a spiral channel that spirals inward to the loading site, the series of anchors arranged along the spiral channel, and the spring configured to urge the series of anchors along the spiral channel toward the loading site. The anchor driver comprises a rod extendable through the loading site in a manner that obstructs access of the series of anchors to the loading site from the spiral channel. Other embodiments are also described.

The tube (1072) has a proximal end defining a distal opening and a proximal opening. An extracorporeal unit (1274, 1474) couples to the proximal end, defines a deployment position, and includes a track (1272, 1472) leading to the deployment position. Each cartridge (1220, 1240) in the series holds a respective tissue anchor (1020) and couples to the extracorporeal unit at a respective initial position. Each cartridge is movable along the track from its initial position to the deployment position, such that the cartridge holds its tissue anchor opposite the proximal opening. An anchor driver (1060) can advance the tissue anchor distally out of its cartridge, through the proximal opening, and through the tube. Each cartridge is then removable from the deployment position, thereby freeing the deployment position for the subsequent cartridge in the series. Other applications are also described.

The application provides a heart valve positioning device, which comprises a first curved structure, a second curved structure, and a third curved structure. The first curved structure forms a spiral curved structure with a first size in a released state. The second curved structure forms a spiral curved structure with a second size in a released state, and the second size is greater than the first size. The second curved structure has a hollow first cavity for the first curved structure to pass through, forming the third curved structure. The distal end of the third curved structure is a free end, and the proximal end is connected with a delivery system. The third curved structure forms a spiral curved structure with a third size in a released state, and the first size is less than the third size and less than or equal to the second size. The embodiment of the application can reduce left ventricular outflow tract obstruction caused by large-scale movement of the anterior leaflet.

A system (100) includes a bioprinter (110) having a nozzle (116) that is transluminally advanceable to the heart via a catheter (120). The bioprinter houses a bioink (140) comprising a biomaterial (142). While the nozzle extends from a distal portion (124) of the catheter, the nozzle can extrude the bioink into the heart such that the biomaterial assumes a three-dimensional implant-shape. Other embodiments are also described.

To provide improved devices and methods for treating a regurgitant valve.SOLUTION: An implantable prosthetic device has a coaption element and at least one anchor. The coaption element is configured to be positioned within a native heart valve orifice to help fill a space where a native valve is regurgitant and form a more effective seal. The coaption element can have a structure that is impervious to blood. The coaption element can be connected to leaflets of the native valve by the anchor.SELECTED DRAWING: Figure 232A

The invention discloses an expandable artificial biological heart valve and belongs to the technical field of medical instruments, the expandable artificial biological heart valve comprises a valve leaflet, a valve frame and a valve seat, the valve frame is of an annular structure, the valve frame is used for supporting the valve leaflet and fixed to the valve seat, the periphery of the valve frame is wrapped with polyester fabric, the valve leaflet is fixed to the valve frame through a suture line, and the valve leaflet is fixed to the valve seat through the suture line. The outer surface of the valve seat is sleeved with a suture ring, the suture ring is fixedly connected with the valve seat through a suture line, the outer surface of the suture ring is sleeved with a polyester fabric tube, and the valve seat has the elastic deformation capacity so as to adapt to size adjustment in the minimally invasive surgery. The valve seat not only can meet the requirement of minimally invasive surgery, but also meets the requirement of repeated valve implantation possibly needed by young valvular disease patients, the service life of the valve is remarkably prolonged, and the postoperative life quality of the patients is remarkably improved.

A valve implant includes an occlusive assembly and a frame coupled to the occlusive assembly. The frame transitions from a collapsed state to an expanded state about a central longitudinal axis and transitioning from the collapsed state to the expanded state causes a proximal end of the frame to expand radially outward from the central longitudinal axis. The valve implant further includes an outer sheet supported on a proximal portion of the frame. The occlusive assembly is supported on a distal portion of the frame such that the inner sheet extends about the central longitudinal axis and an annular opening is defined between the outer sheet and the inner sheet when the frame is in the expanded state.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

The present invention discloses a forming and locking structure for a heart valve repair device, comprising a forming ring body and a buckle structure connected to the front and rear ends of the forming ring body to form the forming ring body into an annular shape; the buckle structure comprises a buckle fixed end and a buckle head end connected to opposite ends of the forming ring body; the buckle head end is provided with a head end guide head, and the head end guide head is provided with a head end traction hole; the buckle fixed end is provided with a fixed end traction hole and a buckle traction line through-hole provided on the tube wall of the buckle fixed end; a buckle traction line is passed through between the head end traction hole, the fixed end traction hole, and the buckle traction line through-hole, and the two ends of the buckle traction line extend outward from the buckle traction line through-hole. By pulling the two ends of the buckle traction line extending outward from the buckle traction line through-hole, the buckle head end and the buckle fixed end are driven to engage, thereby achieving the tail locking of the forming ring body and preventing the forming ring body from shrinking when locked.

A prosthetic mitral valve includes an anchor assembly, a strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The ventricular anchor and the atrial anchor are configured to flare radially outwards relative to the central portion. The annular strut frame is disposed radially within the anchor assembly and is attached to the anchor assembly. The central portion is configured to align with a native valve orifice and the ventricular anchor and the atrial anchor are configured to compress native cardiac tissue therebetween.

A differential pressure regulating device is provided for controlling in-vivo pressure in a body, particular in a heart. The device may include a shunt being positioned between two or more lumens in a body, to enable fluids to flow between the lumens, and an adjustable flow regulation mechanism being configured to selectively cover an opening of the shunt to regulate the flow of fluid through the shunt in relation to a pressure difference between the body lumens. In some embodiments, a control mechanism coupled to the adjustable flow regulation mechanism may be provided to remotely activate the adjustable flow regulation mechanism.

An annuloplasty ring is disclosed. The annuloplasty ring includes an outer tube, a plurality of anchors, and at least one synthetic leaflet. The synthetic leaflets are in mechanical communication with the annuloplasty ring at a plurality of points. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the annuloplasty ring to a heart valve of a patient.

The present application provides a locking device, a locking system and an implant. The locking device includes a shell and a winding assembly at least partially housed in the shell. The winding assembly can rotate relative to the shell. The winding assembly includes a winding member, a connector and a locking member. The locking member is elastic. The locking member is arranged between the winding member and the connector. The winding member is fixedly connected to the connector. The locking member cooperates with the shell to limit the rotation of the winding assembly, and the locking member is configured to be able to break away from the restriction of the shell under the action of an external force. In the locking device, locking system and implant of the embodiments of the present application, when the elastic locking member cooperates with the shell to limit the rotation of the winding assembly, the locking device is in a locked state; when the locking member is deformed by force and breaks away from the restriction of the shell, the locking device is in an unlocked state, at which time the winding assembly can be driven to rotate clockwise or counterclockwise.

An implantable prosthetic posterior mitral valve is described where one variation generally includes a frame. A posterior leaflet having one or more scallops may be connected to the frame such that the scallops extend from the frame for coaptation against a native anterior leaflet when the frame is deployed. At least one arm member may be connected to the frame such that the arm member extends laterally in a curved configuration configured to approximate a curvature of a native mitral annulus when the frame is deployed, and an anchoring leg may be connected to the frame and extend in a superior direction from a posterior side of the frame and defines a capture region between the anchoring leg and the posterior side. The capture region may be sized to receive at least a portion of a native posterior leaflet in an elongated state when the frame is deployed.

The present application discloses an implant, a transcatheter constriction ring system and their applications for reducing the risk of detachment. The implant includes a tightening wire and a plurality of anchoring components. The anchoring component includes an anchor and a threading structure rotatably sleeved on the anchor. The anchor is used for anchoring into heart tissue, and the threading structure is used for connecting the tightening wire. Among them, after a plurality of anchoring components are arranged along the circumferential direction of the heart tissue, the tightening wire is connected to the threading structure, and the tightening wire is located on the same side of the plurality of anchors that are anchored into the heart tissue. In this way, it can be ensured that after the constriction ring is completed, the anchoring components in the middle part are less stressed and the stress is more uniform, avoiding the situation where the anchoring components are stressed greatly, reducing the risk of detachment of the anchoring components, and making the implant safer; at the same time, the acting force of the anchoring components on the heart tissue is reduced, reducing the risk of damage to the heart tissue. In addition, when the tightening wire is tightened to form a constriction ring, the tightening wire moves stably and smoothly, ensuring the stability of the constriction ring and good constriction effect.

A heart valve prosthesis with one or more drug eluting mechanisms embedded in the prosthesis during manufacture.