1421results about "Annuloplasty rings" patented technology

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

A differential pressure regulating device is provided for controlling in-vivo pressure in a body, and in particularly in a heart. The device may include a shunt being positioned between two or more lumens in a body, to enable fluids to flow between the lumens, and an adjustable flow regulation mechanism being configured to selectively cover an opening of the shunt, to regulate the flow of fluid through the shunt in relation to a pressure difference between the body lumens. In some embodiments a control mechanism coupled to the adjustable flow regulation mechanism may be provided, to remotely activate the adjustable flow regulation mechanism.

A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

The present invention discloses a presettable artificial biological aortic valve which comprises a valve seat (1), a valve leaflet stent (2) and three valve leaflets (3), wherein the valve seat (1) is a one-way limiting expandable annular metal seat; the head end of each seat body unit (4) is sequentially provided with a first rivet (7), a limiting protrusion (6) and a first long circular groove (5) from the outside to the inside; the tail end of each seat body unit (4) is sequentially provided with a second long circular groove (8), a second limiting hole (10) and a first limiting hole (9) matched with the limiting protrusion (6), and a second rivet (11) matched with the first long circular groove (5). The presettable artificial biological aortic valve has an original preset state and a normal use state after one-way limiting expansion.

Systems and methods for native heart valve repair includes an anchor. The anchor includes an anchor body configured to transition from a first configuration, in which the anchor body is straightened for transvascular delivery to the native heart valve, to a second configuration comprising at least two turns for implanting at the native heart valve. Two or more of the at least two turns in the second configuration have a diameter smaller than a major axis of the native heart valve.

The application relates to the field of medical devices, in particular to a repair system capable of accurate positioning, which comprises a delivery catheter, a positioning support arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guide wire, the positioning support is arranged at the distal end of the delivery catheter, the positioning support is provided with a plurality of anchoring points distributed in the circumferential direction, the flexible sleeve is provided with a plurality of connecting points arranged in correspondence with the anchoring points, the guide wire passes through the connecting points and the anchoring points corresponding to the connecting points in sequence, and after the positioning support is released, the anchoring mechanism pushes the flexible sleeve, so that the flexible sleeve cooperates with the guide wire and guides the anchoring mechanism to reach each anchoring point along a predetermined route and complete anchoring; the application not only simplifies the structure of the device, but also realizes accurate guidance.

A prosthetic valve includes an annular frame and a skirt. The frame is radially expandable and compressible between a radially compressed configuration and a radially expanded configuration. The skirt has a fold around an inflow end of the frame so as to cover at least a portion of an outer surface of the frame and at least a portion of an inner surface of the frame. When the frame is in the radially expanded configuration, an outer portion of the skirt tightly conforms to the outer surface of the frame and the inflow end of the frame is axially spaced from the fold to form an axially extending gap between the frame and the fold. When the frame is in the radially compressed configuration, the inflow end of the frame extends axially so as to at least partially fill the axially extending gap.

A polymeric mitral heart valve, comprising: valve leaflets (3), a valve stent (1) and a valve ring (2), wherein the valve stent (1) is of a hollow columnar structure, the valve stent (1) comprises a first end (11) and a second end (12), the first end (11) is provided with three column peaks (13) spaced apart in the circumferential direction and column valleys (14) are correspondingly formed; the valve ring (2) is arranged at the periphery of the second end (12) of the valve stent (1), two protruding sections (21) extending towards the first end (11) in the axial direction are formed at the periphery of the valve ring (2) to be capable of corresponding to two of the column peaks (13), and a flat section (22) is formed at a position corresponding to the other column peak (13); the valve further comprises an insert (5), the insert (5) is of a hollow columnar structure matching the valve stent (1), and the insert (5) is suitable for being embedded in the valve stent (1) in the axial direction; the valve leaflets (3), the valve stent (1) and the valve ring (2) undergo one-time injection molding, and the insert (5) is embedded in the valve stent (1) during injection molding to form a whole. By optimizing the structures of the valve ring (2) and the valve stent (1), the adaptability of the valve ring (2) to a native valve ring is improved, the radial support force of the valve stent (1) is improved, and the valve performance is optimized.

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having a leaflet frame and a leaflet construct including one or more leaflets. In some examples, the leaflet construct is coupled to the leaflet frame via a retention element. In some examples, the retention element is in the form of an outer frame that is coaxially arranged with the leaflet frame.

The present invention discloses a prosthetic heart valve comprising at least two valve components, a sealant covering the valve components, and an edge-sealing structure. A space is formed between the valve components covered with the sealant. The edge-sealing structure has a closed end face and connects the ends of the sealant to form a closed space within the space. The prosthetic heart valve provided by the present invention can reduce the risk of thrombosis between the valve components. Because the edge-sealing structure is flexible, it has little effect on the compression and gripping of the prosthetic valve, and the addition of the edge-sealing structure does not affect the normal function of the prosthetic valve.

A first ventricular surface anchor may be placed against the first right ventricular surface, where the first ventricular surface anchor is connected to a first tension member. A first tension anchor against a tension anchor surface of the heart wherein the first tension anchor is connected to a second tension member. The first tension member connected to the first ventricular surface anchor may extend toward the second tension member connected to the first tension anchor; and the first tension member and the second tension member may drag the first right ventricular surface toward the first tension anchor. The surface anchor may include a nitinol frame and an aperture forming an outer perimeter. When the temperature of the nitinol frame is a body temperature, the nitinol frame may have an austenitic state in a deployed configuration. The surface anchor may also include a grommet including a distal tubular portion connected to a proximal finger portion.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

The invention discloses a valve clamping device. The valve clamping device comprises a fixed seat; the first clamping piece and the second clamping piece are hinged to the fixed seat; the clamping assembly comprises a connecting base, a first elastic piece assembly and a second elastic piece assembly, the first elastic piece assembly and the second elastic piece assembly extend out of the two opposite sides of the connecting base, and the fixing base is contained in the connecting base; the first elastic piece assembly and the second elastic piece assembly are matched with the first clamping piece and the second clamping piece respectively to clamp a valve leaflet of a valve, the first elastic piece assembly and the second elastic piece assembly each comprise a clamping elastic piece and a detection elastic piece, and when the clamping elastic pieces are matched with the first clamping piece or the second clamping piece to clamp the valve leaflet, the detection elastic pieces are arranged on the clamping elastic pieces. The detection elastic pieces on the same side can be controlled to move between the joint state where the detection elastic pieces are jointed with the valve leaflet and the detection state where the detection elastic pieces are separated from the valve leaflet so as to detect whether the valve leaflet is clamped at the expected position or not by the clamping elastic pieces and the first clamping piece or the second clamping piece in a matched mode. The invention further provides a valve clamping system using the valve clamping device and a method for detecting the clamping state of the clamping assembly.

The present application relates to the field of medical devices, and specifically to a repair device for preventing valve regurgitation, comprising a mounting bracket, a single anti-reflux prosthesis for replacing the function of a single native valve leaflet, and a fixing member, wherein one end of the single anti-reflux prosthesis is fixed on the mounting bracket, and an atrial segment is provided at the distal end of the mounting bracket, and the atrial segment is configured to adapt to the morphology of the native valve ring tissue, and the atrial segment includes a leak-proof portion, and the proximal end portion of the mounting bracket is anchored in the ventricle by the fixing member, wherein, after the mounting bracket is installed in place, the leak-proof portion abuts against or fits the native valve ring tissue, and when the native valve opens and closes so that the morphology of the native valve ring changes, the leak-proof portion follows the morphological change of the native valve ring and produces adaptive deformation, so that the leak-proof portion always abuts against or fits the native valve ring tissue.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

An enlarged cardiac valve annulus can be reduced in diameter using a cord that is affixed to the annulus by a set of anchors. A knot or fixed loop is disposed at a first end of the cord, and the body of the cord passes through the knot or fixed loop so as to form (a) a loop portion positioned distally beyond the knot or fixed loop and (b) a second portion that runs between the knot or fixed loop and the second end. The body of the cord can slide with respect to the knot or fixed loop. After the anchors are implanted and a bond between the anchors and the annulus is sufficiently strong, pulling the second portion in a proximal direction while holding the knot or fixed loop in place will reduce the circumference of the annulus.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

Modular prosthetic valves are disclosed that may support a customized number of leaflets. e.g., four or more leaflets carried by a support structure, such as a frame or stent, which may be used to replace diseased mitral, aortic, tricuspid, or pulmonary valves.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.

An device for treating a native valve includes a sealing element and an anchoring element. The sealing element is made from a braided mesh material. The sealing element is dimensioned to be deployed in an annulus of a native valve of a heart at a position between native valve leaflets to contact the native valve leaflets during ventricular systole to create a seal to prevent regurgitation of blood from the left ventricle to the left atrium. The sealing element is configured to both be radially expanded and radially reduced while at the position between the native valve leaflets. The anchoring element is adapted for deployment in the heart, the anchoring element coupled to the sealing element and configured to support the sealing element at the desired position between native valve leaflets.

A first ventricular surface anchor can be placed against a first right ventricular surface, wherein the first ventricular surface anchor is connected to a first tension member. A first tension anchor against a tension anchor surface of a heart, wherein the first tension anchor is connected to a second tension member. The first tension member connected to the first ventricular surface anchor can extend towards the second tension member connected to the first tension anchor; and the first tension member and the second tension member, can be draw the first right ventricular surface toward the first tension anchor. The surface anchor can include a nitinol frame forming an outer perimeter and a hole. The nitinol frame can have an austenite state in a deployed configuration when a temperature of the nitinol frame is body temperature. The surface anchor can also include a grommet comprising a distal tubular portion connected to a proximal finger portion.

A split type precisely-anchorable transcatheter mitral valve system comprises a split transcatheter mitral valve anchoring stent (10) and a transcatheter artificial biological mitral valve (20), wherein the shape and structure of the transcatheter mitral valve anchoring stent (10) are matched with the mitral valve real structure after the patient image data is subjected to three-dimensional reconstruction, the transcatheter mitral valve anchoring stent (10) is firstly delivered to the mitral valve position of the patient to be released and deformed, and the transcatheter artificial biological mitral valve (20) is in personalized precise alignment and coaptation with tissues on the mitral valve position of the patient and under the petals; the transcatheter artificial biological mitral valve (20) is delivered into the transcatheter mitral valve anchoring stent (10) to be released, the transcatheter artificial biological mitral valve (20) is released and deformed and expanded to a functional state, the transcatheter mitral valve anchoring stent (10) is again deformed and combined with the expanded transcatheter artificial biological mitral valve (20), and meanwhile, the re-deformation of the transcatheter mitral valve anchoring stent (10) enables the mitral valve anchoring stent (10) to be anchored with the lower leaflet tissue in a preset combination. The split type accurately anchored transcatheter mitral valve system can realize accurate anchoring of transcatheter mitral valve personalized based on a system designed by three-dimensional reconstruction.

The present invention relates to a system for delivering an annuloplasty device for restoring a heart valve annulus from a dysfunctional configuration to a working configuration wherein the annuloplasty device is configured to expand from a preset configuration corresponding to the working configuration of the valve annulus, the system comprising a delivery device, a delivery device is configured to be removably coupled to an annuloplasty device, where the delivery device includes a structure configured to expand from a first configuration to a second configuration, where the second configuration is substantially equal to or greater than a predetermined configuration of the annuloplasty device.

A kit having an annuloplasty implant and a delivery catheter is described, in which the delivery catheter comprises a distal portion configured to form a first curve around a heart valve at a first side of native heart valve leaflets and to form a second curve around the heart valve on a second side of the native heart valve leaflets opposite the first side. The first and second curves connected through a commissure of the heart valve. The annuloplasty implant comprises first and second supports formed from a stent and the first and second supports have retention units.

The present application relates to the field of medical devices, and in particular to a guideable positioning anchoring system, comprising a delivery catheter, a positioning bracket arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guiding mechanism, wherein the positioning bracket is arranged at the distal end of the delivery catheter, and the positioning bracket is provided with a plurality of anchoring points distributed along the circumferential direction, the flexible sleeve is provided with a plurality of connection sites, and the guiding mechanism comprises a plurality of guide wires, which respectively pass through the connection sites and are connected with the anchoring points, wherein the distal end portion of the anchoring mechanism is sleeved in the flexible sleeve, and the flexible sleeve cooperates with the guide wire so that the anchoring mechanism can be guided to each anchoring point along a predetermined route and complete anchoring; the anchoring mechanism in the present invention can be guided to each anchoring point along a predetermined route and complete anchoring, without the need to repeatedly search for the position through images, and the operation is convenient and the accuracy is high.

Prosthetic ring valve assemblies are disclosed. A prosthetic valve ring assembly includes an outer tube and a plurality of anchors. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the prosthetic valve ring assembly to annulus tissue of a patient.

The invention discloses a valve clamping device with adjustable bearing force and a valve clamping system. The valve clamping device comprises a supporting part and a clamping part, the hollow adjusting part is made of a shape memory material, one end of the adjusting part is arranged on the outer side of the supporting part in a sleeving mode and connected with the supporting part, and the other end of the adjusting part can move along the supporting part; the clamping part is arranged on the outer side of the adjusting part in a surrounding manner; the driving part is connected with the clamping part so as to drive the clamping part to be unfolded or folded around the adjusting part; when the clamping part is closed relative to the adjusting part, the near end of the adjusting part does not exceed the near end of the clamping part. Therefore, by means of the valve clamping device, the elastic fitting performance of the valve leaflet and the adjusting part can be improved, and then the adaptability of valve leaflet physiological structures of different patients is improved.