893results about "Annuloplasty rings" patented technology

A differential pressure regulating device is provided for controlling in-vivo pressure in a body, and in particularly in a heart. The device may include a shunt being positioned between two or more lumens in a body, to enable fluids to flow between the lumens, and an adjustable flow regulation mechanism being configured to selectively cover an opening of the shunt, to regulate the flow of fluid through the shunt in relation to a pressure difference between the body lumens. In some embodiments a control mechanism coupled to the adjustable flow regulation mechanism may be provided, to remotely activate the adjustable flow regulation mechanism.

A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

The present invention discloses a presettable artificial biological aortic valve which comprises a valve seat (1), a valve leaflet stent (2) and three valve leaflets (3), wherein the valve seat (1) is a one-way limiting expandable annular metal seat; the head end of each seat body unit (4) is sequentially provided with a first rivet (7), a limiting protrusion (6) and a first long circular groove (5) from the outside to the inside; the tail end of each seat body unit (4) is sequentially provided with a second long circular groove (8), a second limiting hole (10) and a first limiting hole (9) matched with the limiting protrusion (6), and a second rivet (11) matched with the first long circular groove (5). The presettable artificial biological aortic valve has an original preset state and a normal use state after one-way limiting expansion.

The application relates to the field of medical devices, in particular to a repair system capable of accurate positioning, which comprises a delivery catheter, a positioning support arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guide wire, the positioning support is arranged at the distal end of the delivery catheter, the positioning support is provided with a plurality of anchoring points distributed in the circumferential direction, the flexible sleeve is provided with a plurality of connecting points arranged in correspondence with the anchoring points, the guide wire passes through the connecting points and the anchoring points corresponding to the connecting points in sequence, and after the positioning support is released, the anchoring mechanism pushes the flexible sleeve, so that the flexible sleeve cooperates with the guide wire and guides the anchoring mechanism to reach each anchoring point along a predetermined route and complete anchoring; the application not only simplifies the structure of the device, but also realizes accurate guidance.

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

The present invention discloses a prosthetic heart valve comprising at least two valve components, a sealant covering the valve components, and an edge-sealing structure. A space is formed between the valve components covered with the sealant. The edge-sealing structure has a closed end face and connects the ends of the sealant to form a closed space within the space. The prosthetic heart valve provided by the present invention can reduce the risk of thrombosis between the valve components. Because the edge-sealing structure is flexible, it has little effect on the compression and gripping of the prosthetic valve, and the addition of the edge-sealing structure does not affect the normal function of the prosthetic valve.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

The present application relates to the field of medical devices, and specifically to a repair device for preventing valve regurgitation, comprising a mounting bracket, a single anti-reflux prosthesis for replacing the function of a single native valve leaflet, and a fixing member, wherein one end of the single anti-reflux prosthesis is fixed on the mounting bracket, and an atrial segment is provided at the distal end of the mounting bracket, and the atrial segment is configured to adapt to the morphology of the native valve ring tissue, and the atrial segment includes a leak-proof portion, and the proximal end portion of the mounting bracket is anchored in the ventricle by the fixing member, wherein, after the mounting bracket is installed in place, the leak-proof portion abuts against or fits the native valve ring tissue, and when the native valve opens and closes so that the morphology of the native valve ring changes, the leak-proof portion follows the morphological change of the native valve ring and produces adaptive deformation, so that the leak-proof portion always abuts against or fits the native valve ring tissue.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

The present application relates to the field of medical devices, and in particular to a guideable positioning anchoring system, comprising a delivery catheter, a positioning bracket arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guiding mechanism, wherein the positioning bracket is arranged at the distal end of the delivery catheter, and the positioning bracket is provided with a plurality of anchoring points distributed along the circumferential direction, the flexible sleeve is provided with a plurality of connection sites, and the guiding mechanism comprises a plurality of guide wires, which respectively pass through the connection sites and are connected with the anchoring points, wherein the distal end portion of the anchoring mechanism is sleeved in the flexible sleeve, and the flexible sleeve cooperates with the guide wire so that the anchoring mechanism can be guided to each anchoring point along a predetermined route and complete anchoring; the anchoring mechanism in the present invention can be guided to each anchoring point along a predetermined route and complete anchoring, without the need to repeatedly search for the position through images, and the operation is convenient and the accuracy is high.

Prosthetic ring valve assemblies are disclosed. A prosthetic valve ring assembly includes an outer tube and a plurality of anchors. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the prosthetic valve ring assembly to annulus tissue of a patient.

The present invention discloses a valve clamping device and a valve clamping system with sufficient fitting. The valve clamping device with sufficient fitting includes a support part, an adjustment part and a clamping part. The support part has a certain axial length and includes a first end and a second end arranged oppositely; the adjustment part includes a first end and a second end arranged oppositely, and a self-expanding body located between the first end and the second end; the first end of the adjustment part is movably sleeved on the outside of the support part, the second end of the adjustment part is sleeved on the outside of the support part and fixedly connected to the support part, and the first end of the adjustment part is located between the first end of the support part and the second end of the adjustment part; the clamping part is arranged on the outside of the support part and can be expanded or closed relative to the adjustment part. The valve clamping device with sufficient fitting can increase the fitting area between the valve leaflets and the adjustment part, enable the valve leaflets to be fully fitted with the adjustment part, and further improve the clamping force to firmly clamp the valve leaflets.

Devices and methods for the repair of the functioning of heart valves are provided. A device may comprise a ventricular winding having a generally spiral shape, wherein the device is free of any atrial stabilizing section. A method involves positioning the device such that chords associated with the heart valve are positioned within the path of the generally spiral shape of the ventricular winding and turning the ventricular winding such that the chords move closer to the center of the ventricular winding. The ventricular winding draws the chords closer together, thereby pulling the valve leaflets closer together in order to facilitate their coaptation and proper closing. A delivery system for maneuvering and releasing a heart valve repair device comprises an applicator tube and internal rod.

Multiple anchors are transluminally slid distally over and along a first portion of a tether to a heart of a subject. The anchors are anchored to tissue of the heart, with the first portion of the tether extending transluminally to the heart. Within the heart, a bight of the tether is secured to the tissue by the anchors. A second portion of the tether extends from the bight to a second end of the tether. The first portion of the tether is subsequently slidably coupled to the second end of the tether such that the tether forms a closed loop. The tissue is subsequently reshaped by the loop being reduced in size by the first portion being slid through the slidable coupling. Other embodiments are also described.

A prosthetic device for treating a native valve of a heart includes a sealing element and an anchoring element. The sealing element comprises a braided mesh material. The sealing element is dimensioned to be deployed at the native valve. The sealing element is configured to both be radially expanded and radially reduced while at a position between the native valve leaflets. The anchoring element is coupled to the sealing element and is configured to support the sealing element between the native valve leaflets.

A heart valve prosthesis comprising a radially expandable and compressible annular frame is disclosed. The frame comprises a plurality of interconnected rows of cells disposed between an inflow end and an outflow end of the frame, the interconnected rows of cells comprising a plurality of outflow struts defining the outflow end and a plurality of inflow struts defining the inflow end. The frame further comprises a plurality of tip regions formed at the inflow end and the outflow end, each tip region curved between two angled strut portions and forming one of the outflow struts or one of the inflow struts with the two angled strut portions.Each tip region has a reduced width and a length extending at least 25% of the total length of the outflow strut or the inflow strut, the reduced width being less than the width of the two angled strut sections.

Various examples are provided related to a cardiac valve repair device. In one example, the device includes an outer structure with outer blocks, and inner blocks. Each outer block can include an outer magnet pack disposed within in outer block void, at least one tension wire channel extending through the outer block between a first end and a second end and along the outer block void, a connection point on each of the first end and the second end, and attachment openings on each of a first side and a second side extending between the first end and the second end. The outer structure can also include tension wires extending through corresponding tension wire channels and connectors that can couple the outer blocks. Each inner block includes an inner magnet pack disposed within an inner block void and attachment openings that correspond to the attachment openings of the outer blocks.

An implantable prosthetic device has a coaptation element. At least a portion of the coaption element is formed from the strip of material. A pair of paddles are connected to the coaption element. The paddles are movable between an open position and a closed position. The paddles are configured to attach to the native valve of the patient.

A system comprises a series of anchors, an anchor-storage device, and an anchor driver that is slidably coupled to the anchor-storage device. The anchor-storage device comprises a spring, and a housing, shaped to define: (i) a loading site, and (ii) a spiral channel that spirals inward to the loading site, the series of anchors arranged along the spiral channel, and the spring configured to urge the series of anchors along the spiral channel toward the loading site. The anchor driver comprises a rod extendable through the loading site in a manner that obstructs access of the series of anchors to the loading site from the spiral channel. Other embodiments are also described.

The tube (1072) has a proximal end defining a distal opening and a proximal opening. An extracorporeal unit (1274, 1474) couples to the proximal end, defines a deployment position, and includes a track (1272, 1472) leading to the deployment position. Each cartridge (1220, 1240) in the series holds a respective tissue anchor (1020) and couples to the extracorporeal unit at a respective initial position. Each cartridge is movable along the track from its initial position to the deployment position, such that the cartridge holds its tissue anchor opposite the proximal opening. An anchor driver (1060) can advance the tissue anchor distally out of its cartridge, through the proximal opening, and through the tube. Each cartridge is then removable from the deployment position, thereby freeing the deployment position for the subsequent cartridge in the series. Other applications are also described.

Tensioning devices are described that include a handle, a line carriage configured to be coupled to a tensioning line, and an electrical motor assembly configured to axially translate the tensioning line relative to the handle to thereby modify a tension in the tensioning line. Other implementations are also described, including a tensioning device including a handle, a line carriage configured to be coupled to a tensioning line, and a manually-manipulatable actuator configured to be selectively transitioned between a fine-tensioning configuration and a gross-tensioning configuration.

The application provides a heart valve positioning device, which comprises a first curved structure, a second curved structure, and a third curved structure. The first curved structure forms a spiral curved structure with a first size in a released state. The second curved structure forms a spiral curved structure with a second size in a released state, and the second size is greater than the first size. The second curved structure has a hollow first cavity for the first curved structure to pass through, forming the third curved structure. The distal end of the third curved structure is a free end, and the proximal end is connected with a delivery system. The third curved structure forms a spiral curved structure with a third size in a released state, and the first size is less than the third size and less than or equal to the second size. The embodiment of the application can reduce left ventricular outflow tract obstruction caused by large-scale movement of the anterior leaflet.

Aspects of the disclosure include delivery devices for transcatheter delivery of a cardiac implant. Delivery devices can include a handle assembly as well as a piston mount connected to the handle assembly and having a distal portion terminating at a nose cap. The distal portion includes a stop extending radially from and fixed to the distal portion. The delivery device further includes a capsule assembly including a biasing element for selectively sheathing the implant and a plurality of retraction members secured about a distal end of the biasing element to control deployment of the implant. In various examples, the biasing element is a helical compression spring and the implant is a prosthetic tricuspid heart valve. Methods of loading a delivery device and delivering an implant are also disclosed.

The invention provides a valve delivery system and a using method thereof.The valve delivery system comprises a first shell, a sheath tube assembly, a bending control assembly, a second shell, a near-end assembly, a hanging lug assembly and a far-end assembly, the sheath tube assembly and the bending control assembly are arranged in the first shell, and a positioning piece release tube can move in the axis direction of the first shell; the bending control assembly can control the bending degree of the positioning piece release tube, the far-end release tube of the far-end assembly and the near-end release tube of the near-end assembly are arranged in the positioning piece release tube, the far-end release tube is connected with the far-end hanging lug base, the near-end release tube is connected with the near-end hanging lug base, and the valve support is loaded on the hanging lug assembly. The valve stent is circumferentially positioned by rotating the second shell, and the valve stent can be axially delivered and released by controlling the near-end assembly and the far-end assembly. According to the valve delivery system, delivery and release of the valve stent are achieved through one-time admission, the error-tolerant rate and accuracy of release of the valve stent are improved, and operation is convenient and fast.

A system (100) includes a bioprinter (110) having a nozzle (116) that is transluminally advanceable to the heart via a catheter (120). The bioprinter houses a bioink (140) comprising a biomaterial (142). While the nozzle extends from a distal portion (124) of the catheter, the nozzle can extrude the bioink into the heart such that the biomaterial assumes a three-dimensional implant-shape. Other embodiments are also described.

To provide improved devices and methods for treating a regurgitant valve.SOLUTION: An implantable prosthetic device has a coaption element and at least one anchor. The coaption element is configured to be positioned within a native heart valve orifice to help fill a space where a native valve is regurgitant and form a more effective seal. The coaption element can have a structure that is impervious to blood. The coaption element can be connected to leaflets of the native valve by the anchor.SELECTED DRAWING: Figure 232A

The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal. The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.