445results about "Annuloplasty rings" patented technology

A heart valve repair apparatus is disclosed. The apparatus has a radially expandable ring having a first ring component connectable to a second ring component by a pair of securing members, a tube structure, and a net structure extending distally from the ring to the tube structure. The net structure comprises a plurality of cells, each of which defines a hollow space which may comprise a quadrilateral shape or a pentagon shape. The net structure also comprises a plurality of positioning cords connecting the plurality of cells to the tube structure. In some embodiments, one or more tabs are arranged to project outwardly from an inner circumferential surface of the ring, aligned and dimensioned to allow passage of a tether therethrough.

The application relates to the field of medical devices, in particular to a repair system capable of accurate positioning, which comprises a delivery catheter, a positioning support arranged in the delivery catheter, an anchoring mechanism, a flexible sleeve and a guide wire, the positioning support is arranged at the distal end of the delivery catheter, the positioning support is provided with a plurality of anchoring points distributed in the circumferential direction, the flexible sleeve is provided with a plurality of connecting points arranged in correspondence with the anchoring points, the guide wire passes through the connecting points and the anchoring points corresponding to the connecting points in sequence, and after the positioning support is released, the anchoring mechanism pushes the flexible sleeve, so that the flexible sleeve cooperates with the guide wire and guides the anchoring mechanism to reach each anchoring point along a predetermined route and complete anchoring; the application not only simplifies the structure of the device, but also realizes accurate guidance.

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

A heart valve prosthesis comprising a radially expandable and compressible annular frame is disclosed. The frame comprises a plurality of interconnected rows of cells disposed between an inflow end and an outflow end of the frame, the interconnected rows of cells comprising a plurality of outflow struts defining the outflow end and a plurality of inflow struts defining the inflow end. The frame further comprises a plurality of tip regions formed at the inflow end and the outflow end, each tip region curved between two angled strut portions and forming one of the outflow struts or one of the inflow struts with the two angled strut portions.Each tip region has a reduced width and a length extending at least 25% of the total length of the outflow strut or the inflow strut, the reduced width being less than the width of the two angled strut sections.

The application provides a heart valve positioning device, which comprises a first curved structure, a second curved structure, and a third curved structure. The first curved structure forms a spiral curved structure with a first size in a released state. The second curved structure forms a spiral curved structure with a second size in a released state, and the second size is greater than the first size. The second curved structure has a hollow first cavity for the first curved structure to pass through, forming the third curved structure. The distal end of the third curved structure is a free end, and the proximal end is connected with a delivery system. The third curved structure forms a spiral curved structure with a third size in a released state, and the first size is less than the third size and less than or equal to the second size. The embodiment of the application can reduce left ventricular outflow tract obstruction caused by large-scale movement of the anterior leaflet.

A system (100) includes a bioprinter (110) having a nozzle (116) that is transluminally advanceable to the heart via a catheter (120). The bioprinter houses a bioink (140) comprising a biomaterial (142). While the nozzle extends from a distal portion (124) of the catheter, the nozzle can extrude the bioink into the heart such that the biomaterial assumes a three-dimensional implant-shape. Other embodiments are also described.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

A differential pressure regulating device is provided for controlling in-vivo pressure in a body, particular in a heart. The device may include a shunt being positioned between two or more lumens in a body, to enable fluids to flow between the lumens, and an adjustable flow regulation mechanism being configured to selectively cover an opening of the shunt to regulate the flow of fluid through the shunt in relation to a pressure difference between the body lumens. In some embodiments, a control mechanism coupled to the adjustable flow regulation mechanism may be provided to remotely activate the adjustable flow regulation mechanism.

An implantable prosthetic posterior mitral valve is described where one variation generally includes a frame. A posterior leaflet having one or more scallops may be connected to the frame such that the scallops extend from the frame for coaptation against a native anterior leaflet when the frame is deployed. At least one arm member may be connected to the frame such that the arm member extends laterally in a curved configuration configured to approximate a curvature of a native mitral annulus when the frame is deployed, and an anchoring leg may be connected to the frame and extend in a superior direction from a posterior side of the frame and defines a capture region between the anchoring leg and the posterior side. The capture region may be sized to receive at least a portion of a native posterior leaflet in an elongated state when the frame is deployed.

Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A preferred embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve portion. The prosthetic valve further comprises at least one ventricular anchor coupled to the main body and disposed outside of the main body. A space is provided between an outer surface of the main body and the ventricular anchor for receiving a native mitral valve leaflet. The prosthetic valve preferably includes an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for delivering and implanting the prosthetic valve are also described.

A medical device (20) for repairing a heart valve of a patient, comprising a coaptation member (21) and a pair of blades (22) arranged at two sides of the coaptation member (21) in the thickness direction. The coaptation member (21) comprises: an extension portion (212) extending in the length direction and having one end connected to the pair of blades (22); and an acting part (211) connected to the other end of the extension part (212) and having a width greater than the width of the extension part (212). The configuration that the coaptation member (21) has an acting portion part (211) provided at one end of the coaptation member (21) and having a greater width improves the range of action of the coaptation member (21), such that only one medical device (20) is required to effectively improve the regurgitation condition of a patient with a large heart. Therefore, for a patient with a larger heart, the use of the medical device (20) can reduce the cost and difficulty of surgery.

Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and / or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.

The application provides a kind of replacement valve device and its support by catheterization, it is related to heart valve technical field.The replacement valve support by catheterization includes support main body, anchoring structure, skirt support structure and sealing membrane.The sealing membrane is circumferentially closed cylindrical structure, sealing membrane includes the first sealing section and the second sealing section being arranged along the axial direction and being connected with each other, the first sealing section is tightly arranged on part or all of skirt support structure, the second sealing section is tightly arranged on part or all of support main body;Sealing membrane is arranged on the inner side and / or outer side of skirt support structure and support main body.The application can solve the problem that sealing membrane and valve support do not fit in the prior art, poor sealing, leading to sealing membrane in blood, leading to paravalvular leakage or causing other complications, with high degree of fit, good sealing, can avoid sealing membrane in blood, effectively avoid paravalvular leakage or cause other complications.

Disclosed herein are implantable prosthetic valves having outer sealing member comprising a bulge in the expanded configuration. The bulge can be configured to provide sealing against native anatomy when the valve is implanted and to assist in minimizing a paravalvular leakage. In addition, disclosed herein are methods of making the prosthetic valves.

The invention belongs to the technical field of medical instruments, and particularly relates to a full-catheter aortic root repair system and an implantation method.The full-catheter aortic root repair system comprises an aortic valve ring, an arch-shaped cambered surface is arranged on the upper surface of the aortic valve ring, a through hole is formed in the upper surface of the arch-shaped cambered surface, and a branch vein frame is fixedly installed in the through hole in the top of the arch-shaped cambered surface; the grid end of the frame body, the kidney-shaped frame block and the aortic valve ring are tightly connected, the positioning side lugs and the branch pulse frame are cooperatively positioned, it is ensured that the system stably fixes and supports valve leaflets at the root of the aorta to be matched with the deformation cavity A, normal aortic valve opening and closing can be accurately simulated, one-way flow of blood is guaranteed, and the branch pulse frame can be accurately aligned with a coronary artery opening; meanwhile, during the operation, the shape of the containing membrane flap can be adjusted through angiography monitoring in combination with a control silk thread, accurate covering and sealing of a lesion area are achieved, complications such as perivalvular leakage are effectively reduced, and the treatment effect of aorta root diseases and long-term prognosis of patients are remarkably improved.

The application discloses a heart chamber pressure regulating device, which is a cylindrical structure and comprises, in the axial direction of the cylindrical structure, an atrial septum passage and an outflow tract arranged in sequence along the blood flow direction; the side of the atrial septum passage, which is opposite to the outflow tract, is provided with an inflow port; a one-way open valve is arranged in the outflow tract; and the cylindrical structure is provided with a first positioning part and a second positioning part which are respectively arranged on the two sides of the atrial septum. The heart chamber pressure regulating device can form a one-way open valve structure on the atrial septum, is stable in position when cooperating with the atrial septum, can be recycled when the release position is improper, and can be released again.

An implantable prosthetic valve comprises an annular frame that is radially expandable from a radially compressed state to a radially expanded state. The frame has an inflow end, an outflow end, and a longitudinal axis extending from the inflow end to the outflow end. The prosthetic valve also comprises a plurality of leaflets positioned to regulate a flow of blood from the inflow end to the outflow end of the frame, and a skirt assembly. The skirt assembly comprises a laminate having a textile layer sandwiched between a first encapsulation layer and a second encapsulation layer. The first and second encapsulation layers are made of an elastomer and the textile layer comprises a first set of yarns and a second set of yarns interwoven with the first set of yarns, wherein the first and second sets of yarns are non-perpendicular and non-parallel to the longitudinal axis.

Devices, systems, and methods for releasing a catheter from an implant may include a catheter comprising first and second elongate elements, first and second elongate element lumens, a tissue anchor lumen, apertures corresponding to each of the lumens, and retaining portions between adjacent apertures. The first elongate element may extend out of its lumen through the first elongate element aperture, across the retaining portion transversely with respect to a longitudinal axis, and towards the second elongate element aperture. The first elongate element may then extend into the second elongate element aperture, loop over the second elongate element, and extend back across the retaining portion and into the first elongate element lumen. In some instances, the second elongate element is retracted to uncouple the first and second elongate elements from each other and to open a channel for the release of tethered tissue anchors.

Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and / or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.

In certain aspects, the invention relates to a method for generating a mitral repair ring for a corresponding mitral valve, comprising the steps of generating (S1) a reference circumference (13) indicative of said valve ring (110); generating (S2) a reference grid (2); inscribing (S3) said reference circumference (13) in said reference grid (2); combining (S4) said reference circumference (13) with a plurality of characteristic measures (15, 16, 17, r1 -r6) of said mitral valve (100); generating (S5) a three-dimensional reference grid (250); identifying (S6) on said three-dimensional reference grid (250) a plurality of deformation points (300-302) of said reference circumference (13); deforming said reference circumference (13) at said deformation points (300-303) so as to obtain a geometric model (10) of said mitral repair ring (10'); and generating said mitral repair ring (10') from said obtained geometric model (10). The invention also relates to the mitral repair ring obtained by means of the aforesaid method and to its use in mitral annuloplasty.

An annuloplasty band and method of implantation are provided that are shaped and sized to avoid adjacent aortic valve structures, providing better protection against dehiscence along the muscular mitral annulus. [Solution] The band is asymmetric and, when implanted, spans a longer distance around the posterior commissure of the mitral valve annulus than the anterior commissure. The band has a saddle shape with a posterior, upward arcuate portion centered on the short axis of the mitral valve annulus, with a longer span extending clockwise from the upward arcuate portion than counterclockwise. The longer span may be approximately 150°, while the shorter span extends approximately 90°. The set of rings may have different saddle profiles and different planar shapes for different sized bands. The method includes implanting the band so that it extends across the posterior leaflet and extends a short distance beyond the posterior commissure outside the anterior leaflet.

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

A prosthetic implant including an anchor member; at least one resilient tethering strut extending from the anchor member; a coaptation structure coupled to an end of the at least one resilient tethering strut; and a tensioning unit extending between the anchor member and the coaptation structure. The tensioning unit including a flexible hollow tubing, and a tensioning wire extending therethrough with a first end of the tensioning wire fixed at a junction between a first end of the flexible hollow tubing and the coaptation structure and with a second end of the tensioning wire extending out from a second end of the flexible hollow tubing. The second end of the tensioning wire being pullable away from the second end of the flexible hollow tubing to bend the flexible hollow tubing and the at least one resilient tethering strut to move the coaptation structure relative to the anchor member.

Provided is a valve implantation device with the assistance of a heart isolation device, which includes a valve, a heart isolation device, and a valve connection device, wherein the heart isolation device includes an isolation device body; the isolation device body is provided with a positioning part; the isolation device body is fixed on a heart tissue through the positioning part; the valve connection device includes a first connection part; one side of the first connection part is connected with the valve; the isolation device body is provided with a second connection part; and the first connection part and the second connection part are connected during use. The device of the present disclosure can improve the cardiac function before / during valve implantation and increases the effectiveness of an operation. Fixing the valve by the hook-type structure can reduce metal objects required for replacement and avoid potential injury to a heart valve structure. A connector structure connected to the valve stably locates the valve and accurately releases the height of the valve, so that paravalvular leak and injury to a valve annulus plane can be prevented.

An implantable prosthetic valve (10, 200) comprises an annular frame (12) that is radially expandable from a radially compressed state to a radially expanded state. The frame (12) has a longitudinal axis (L). The prosthetic valve (10, 200) also comprises a plurality of leaflets (40) positioned to regulate a flow of blood from the inflow end to the outflow end of the frame (12), and a skirt assembly (15). The skirt assembly (15) comprises a laminate having a textile layer sandwiched between a first encapsulation layer (84) and a second encapsulation layer (86). The first and second encapsulation layers are made of an elastomer and the textile layer comprises a first set of yarns (302) and a second set of yarns (304) interwoven with the first set of yarns, wherein the first and second sets of yarns are non-perpendicular and non-parallel to the longitudinal axis.

Embodiments of the present application relate to the field of implantable prostheses, and particularly to a repair system for annulus tissue, which comprises a plurality of first repair devices, a plurality of second repair devices, a sheath and a plurality of locking wire devices. The repair system for annulus tissue provided by embodiments of the present application can precisely repair the position of annulus tissue in need of repair by screwing the anchor into the position of annulus tissue in need of repair, and the anchor screwed into the annulus tissue is not easy to be separated from the annulus tissue, which can increase the reliability of the fixed connection between the anchor and the annulus tissue, thereby facilitating to ensure the effect of repairing the annulus tissue; and the anchor is connected with the posterior leaflet by the first repair device and connected with the anterior leaflet by the second repair device, so as to meet the need of the reliability of the fixed connection between the anchor and the anterior leaflet of the annulus tissue and the posterior leaflet of the annulus tissue, thereby facilitating to ensure the effect of repairing the annulus tissue.

In certain aspects of the present disclosure, a computer-implemented method includes receiving a 3D imaging of a heart valve in a pre-operative state. The method includes generating a segmented heart valve by segmenting the heart valve of the 3D imaging. The method includes simulating a surgical procedure on the parameterized heart valve. The method includes determining at least one post-operative outcome based on simulating the surgical procedure on the parameterized heart valve. Systems and machine-readable media are also provided.

The application relates to a valve clamping device and a valve clamping system. The valve clamping device comprises a center seat, a locking piece, a transmission piece and a plurality of support arms; the support arms are arranged around the center seat and comprise a large arm and a small arm which are hingedly connected, the large arm is hingedly connected with the center seat through a first rotating shaft, and the small arm is connected with the transmission piece through a second rotating shaft; the locking piece is arranged in the center seat and has a first mode and a second mode, when the locking piece is in the first mode, the first rotating shaft is locked, and when the locking piece is in the second mode, the locking on the first rotating shaft is released; wherein when the locking piece releases the locking on the first rotating shaft, the first rotating shaft can move along the axial direction of the center seat to open or close the clamping piece. The valve clamping device can be firmly locked through the locking piece after the valve clamping device is sent to the lesion position and folded, the number of parts of the valve clamping device is reduced, and the assembly difficulty of the valve clamping device is reduced.

The present disclosure describes a holder for an annuloplasty ring that is detached using a single cut. The annuloplasty ring is mounted around the periphery of the holder without the use of connecting sutures. The holder has a proximal plate that defines a lip on one side of the ring and a distal retainer that defines a second lip on the other side that retains the ring around the holder perimeter. The distal retainer is formed of two hinged wings. When the annuloplasty ring is delivered and secured to an implantation site, a truss suture maintains the holder in a trussed configuration. Once the ring is secured at the annulus, the truss suture is severed with a single cut, enabling the hinged wings to pivot and enabling the holder to be pulled away from the ring.