93 results about "Native valve" patented technology

The invention relates to a heart valve docking device and a system for treating a native valve of a patient. In various embodiments, the device is configured to repair a native heart valve or to secure a prosthetic heart valve within a native valve of a patient's heart. An embodiment of the apparatus includes at least an upper coil and a lower coil, wherein the apparatus is configured to assume an axially expanded state in which the entire upper coil is positioned on a first side of the lower coil relative to the central axis and an axially compressed state in which at least a portion of the upper coil is positioned on a second side of at least a portion of the lower coil opposite the first side relative to the central axis.

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

Docking devices for securing a prosthetic valve at a native valve are provided. The docking device can include a coil and a guard member. The coil includes a plurality of helical turns when in a deployed orientation. The guard member may be attached to the coil by being coupled to at least a portion of a helical turn thereof. The docking devices include a atrial functional turn configured to enhance the transient stage stability of the docking device in the left atrium of the heart.

A catheter assembly for retaining a prosthetic valve as the prosthetic valve is guided to a point of delivery within a patient is provided with radioscopic markers. The markers are distributed within the catheter assembly such that an observer may discern a rotational orientation of the assembly from a radioscopic image of the assembly within the patient. Delivery of the prosthetic valve may include aligning the markers with the commissures of the prosthetic valve and radioscopic observation of the location or movement of the markers to rotationally align the prosthetic valve with a native valve within the patient, such as by aligning the commissures of the prosthetic valve with the commissures of the native valve.

A valve repair device, e.g., for treating mitral valve regurgitation, includes a tubular body defining a longitudinal axis, paddles supported by the tubular body and movable to change abduction of the paddles relative to the longitudinal axis, and retention members supported by the tubular body proximal the paddles and similarly movable to change abduction of the retention members relative to the longitudinal axis to facilitate capture of native valve leaflets between pairs of paddles and retention members. Movement of the paddles and / or retention members is provided by one or more control mechanisms including a collar a shaft extending within the tubular body. Each shaft is threadedly engaged to a respective collar and coupled to one or more of the movable elements such that, when the collar is rotated, the shaft translates to change abduction of the movable element relative to the longitudinal axis.

A capsule of a delivery system for a transcatheter heart valve prosthesis includes markers for rotationally orienting the capsule within a native valve. The capsule includes markers that are sized and located on the capsule such that when viewed in a cusp overlap viewing angle image, the markers indicate whether the capsule is in a desired rotational orientation. Methods for rotationally aligning a capsule of a delivery system containing a transcatheter heart valve prosthesis within a native valve are also provided.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

A prosthetic tricuspid heart valve system includes a collapsible anchor frame and a collapsible prosthetic heart valve. The anchor includes a support structure having a waisted central portion, and atrial and ventricular flared portions sized to clamp a native valve annulus. Atrial and ventricular sheets are coupled to the atrial and ventricular flared portions, and each include a central aperture. A generally cylindrical fabric valve-receiving member has an inflow end coupled to the atrial sheet and an outflow end coupled to the ventricular sheet to provide a conduit through the valve-receiving member between the atrial and ventricular sheet. The prosthetic heart valve may include a stent and a plurality of prosthetic leaflets, the prosthetic heart valve configured to be expanded into and received within the valve-receiving member of the anchor frame.

The application provides a valve anchoring device, a guide device and a method for anchoring a prosthetic valve, mainly comprising an anchoring structure and a positioning member, wherein the anchoring structure has a first anchoring member and a second anchoring member extending from both sides of a combination member, the positioning member is connectable to the combination member, the combination member passes through a commissure of a leaflet of a heart tissue, the positioning member is positioned at one side of a heart atrioventricular valve adjacent to an atrium, the first anchoring member and the second anchoring member are positioned at one side of the heart atrioventricular valve adjacent to a ventricle, and the first anchoring member and the second anchoring member are cooperatively matched to anchor the prosthetic valve, so that the prosthetic valve is positioned relative to a native valve of the heart tissue. Therefore, the anchoring effect of the prosthetic valve can be improved.

The present invention relates to an atrioventricular heart valve prosthesis implantable, for example, into the heart of a mammal. The heart valve prosthesis comprises a collapsible-expandable tubular stent having a lumen, preferably having an opening cross-section or area during use or in a fully expanded state of the stent that is smaller than an opening area of a native atrioventricular heart valve to be replaced by the heart valve prosthesis. The heart valve prosthesis further includes an inner valve tip disposed within the lumen of the tubular stent that closes the heart valve by resting against each other, an outer valve leaflet that closes against the native valve leaflet, and at least one anchor wire connected directly or indirectly to the tubular stent. The invention also relates to a method for manufacturing a heart valve prosthesis and to a method for inserting a heart valve prosthesis.

The utility model relates to the technical field of medical instruments, in particular to an artificial valve clamping piece and a conveying system. The artificial valve clamping piece comprises a clamping piece body, a connecting wire and a traction structure, the clamping piece body comprises a pipe body and a plurality of through holes formed in the pipe body, the pipe body is in a wave shape, and the two ends of the pipe body are closed to form a ring shape; the connecting wire penetrates into the tube body, and the end part of the connecting wire penetrates through the through hole in the tube body and then is suitable for being connected with the artificial valve; the traction structure comprises a traction wire, the traction wire is arranged in the pipe body in a penetrating mode through a through hole in the pipe body, and the traction wire is suitable for being connected with a conveying system. The clamping piece is of a periodic wave-shaped or fluctuating annular structure, can be fixed to the periphery of the outer surface of the artificial valve, can be radially compressed and expanded according to the size of the internal artificial valve, and is matched with the artificial valve to clamp the autologous valve leaflet, so that the artificial valve can be stably anchored at an accurate position without displacement, and meanwhile, the clamping piece can be used for clamping the autologous valve leaflet. The clamping device can reduce the occurrence risk of perivalvular leakage.

This disclosure relates to an artificial heart valve for replacing a natural heart valve, comprising: an annular stent including: a mesh structure serving as a circumferential sidewall of the stent; and a leaflet structure, each leaflet being attached to the stent and having a first portion disposed within the stent and a second portion rolled up to the proximal peripheral side of the stent. As the heart grows, the stent can be expanded after the artificial heart valve is anchored to the heart, thereby allowing the artificial heart valve to function in different states without replacement. The edge end of the second portion of each leaflet is connected to the stent at a location between the distal and proximal ends of the stent, but not fixed to the proximal end of the stent. In at least one state, the size of each leaflet exceeds the fit size of the stent in that state, and each leaflet has a redundant portion that hangs freely from the distal to the proximal end to a location away from the stent, thereby allowing the leaflet to be sized away from the stent to form a more functional valve.

Provided are an artificial intelligence AI-based simulation device and method for supporting procedure planning in transcatheter aortic valve implantation. The device receives patient-specific medical images, such as computed tomography data, and generates a three-dimensional (3D) model of the aortic root and native valve. An artificial valve is virtually inserted into the 3D model, and the virtual implantation model is automatically converted into mesh data suitable for Computational Fluid Dynamics (CFD) and Fluid-Structure Interaction (FSI) analysis. The processor performs CFD / FSI simulations to evaluate hemodynamic changes, structural stresses, and potential device-tissue interactions. Based on the analysis, the system outputs predicted risks of procedure-related complications (including coronary obstruction, annular rupture, paravalvular leakage, and valve deformation) and provides guideline data for selecting valve size, implantation depth, and insertion angle. The disclosed device and method enable accurate, patient-specific prediction and visualization, thereby assisting clinicians in establishing safe and optimized TAVI procedure plans.

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device with an elevated valve section and comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and / or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

A heart valve prosthesis can be delivered within a native heart valve annulus using a delivery system that encases the heart valve prosthesis and sequentially permits expansion of a valve clasper and a lattice frame of the valve prosthesis. A sheath of the delivery system can be proximally retracted to permit the sinus locator to expand. Thereafter, a tubular member can be actuated to permit expansion of the lattice frame. Further, a clasper pusher of the delivery system, coupled to the tubular member, can be used to release a proximal portion of the sinus locator after release of the lattice frame. The delivery system can enable sinus locator engagement within the native annulus, sandwiching native valve leaflets between the expanded lattice frame and sinus locator, and thereafter permit disengagement of the sinus locator from the clasper pusher after the lattice frame expands.

A docking device for securing a prosthetic valve at a native valve includes a coil having a plurality of helical turns when deployed at the native valve and a guard member attached to the coil. The guard member is movable between a radially compressed state and a radially expanded state. The guard member includes a plurality of flaps. Each flap includes a rounded head portion and a tapered base portion. The head portion is wider than the base portion when the guard member is in the radially expanded state.

comprising a working catheter (3) and at least one tool being configured to slidably move through the working catheter (3); characterized by the fact that said tool is an expandable stent (26) configured to allow an opening of an aortic native valve, the stent (26) furthermore comprising an ultrasonic transducer (25).

A delivery system includes a delivery sheath with a control device and at least one supra-annular support being movable through a lumen of the delivery sheath. The control device includes a connection member coupled to a distal end of a control catheter. The connection member is configured to removably couple to the prosthetic valve at a proximal position along a supra-annular portion of the prosthetic valve. The control device is operable to advance the prosthetic valve in a compressed configuration through the delivery sheath and to at least partially deploy the prosthetic valve in an expanded configuration into a native valve annulus. The supra-annular support(s) is / are removably coupleable at one or more positions along the supra-annular portion of the prosthetic valve and is / are configured to stabilize or actuate at least a portion of the prosthetic valve relative to an annular plane of a native heart valve during deployment.

Systems and methods are provided for an annuloplasty device and delivery system for treating valvular regurgitation. The annuloplasty device (e.g., a transcatheter annuloplasty ring) may include a tube having anterior and posterior anchors that may transition from a constrained state within the tube to a deployed state in which anchors extend through windows of the tube into tissue at the native valve site. Each anchor may include valvular and atrial anchors as well as anchors having different shapes (e.g., a curved anchor and a non-curved anchor). The annuloplasty device may be delivered to the native valve site via a catheter and the annuloplasty device may be manipulated within the patient's heart using a delivery handle to selectively deploy anchors while closing the anterior-to-posterior distance of the valve to treat valvular regurgitation.

The invention relates to an artificial cuspid valve supporting structure and an artificial cuspid valve device. The artificial cuspid valve supporting structure comprises a cuspid valve supporting body and a supporting part. The sharp valve supporting body is used for being fixed to the inner wall of a native valve ring, a blood flow channel is constructed in the sharp valve supporting body, and the blood flow channel is used for being communicated with an atrium and a ventricle and used for containing an artificial valve leaflet; one end of the supporting part is connected with the cuspid valve supporting body, and the other end of the supporting part is used for elastically abutting against the inner wall of the atrium so as to apply acting force towards the ventricle to the cuspid valve supporting body. According to the application, one end of the supporting part is connected with the cusp valve supporting body, and the other end of the supporting part is used for elastically abutting against the inner wall of the atrium to apply the acting force towards the ventricle to the cusp valve supporting body, so that the supporting part provides stable supporting force for the cusp valve supporting body to prevent the cusp valve supporting body from being impacted to the atrium; and the stability of connection between the sharp valve supporting body and the inner wall of the native valve ring is improved.

A prosthetic heart valve for replacement of a native heart valve having a native valve annulus includes a stent body having a proximal end adjacent an inflow end and a distal end adjacent an outflow end and including an annulus section, the stent body having a radially collapsed condition and a radially expanded condition, one or more prosthetic valve elements mounted to the stent body and operative to allow flow in an antegrade direction from the inflow end to the outflow end but to substantially block flow in a retrograde direction from the outflow end to the inflow end, a cuff coupled to the stent body, the cuff having a mobile portion that is moveable relative to the stent body, and at least one engagement element remote from the stent body.

A delivery catheter is in various embodiments configured to deliver an anchoring device to a native valve annulus of a patient's heart, where the anchoring device can better secure a prosthesis at the native annulus. The delivery catheter may include a flexible portion configured to form a spiral shape in embodiments.

A docking device for securing a prosthetic valve at a native valve includes a coil having a plurality of helical turns when deployed at the native valve, and a guard member attached to the coil. The guard member is movable between a radially compressed state and a radially expanded state. The guard member includes a plurality of petals. Each petal includes a rounded head portion and a tapered base portion. The head portion is wider than the base portion when the guard member is in the radially expanded state.

To provide a deployment tool intended to facilitate implantation of an implant, such as a prosthetic device (e.g., a prosthetic valve), at one of the native mitral, aortic, tricuspid, or pulmonary valve regions of a human heart.SOLUTION: The delivery catheter, in various embodiments, is configured to deliver the anchoring device to an annulus of a native valve of a patient's heart, where the anchoring device can better secure the prosthesis to the native valve annulus. The sheath catheter may be utilized to deliver the delivery catheter and the catheter for deploying the prosthetic valve to the anchor device.SELECTED DRAWING: Figure 27

The present application relates to the field of biomaterials, and particularly relates to a biomimetic biological valve. The biomimetic biological valve is obtained by wrapping a non-crosslinked biological basement membrane around a crosslinked extracellular matrix material to form a sandwich structure. The basement membrane cooperates with the crosslinked extracellular matrix material, fully plays the excellent regenerative repair performance and the characteristics of being rich in bioactive factors of the basement membrane, effectively promotes the growth and adhesion of endothelial cells on the surface of the material, and constructs a tissue structure similar to the natural valve leaflet. The biomimetic biological valve exhibits excellent anti-calcification performance and excellent dynamic mechanical stability and compliance, significantly inhibits the abnormal adhesion of platelets and blood cells, greatly improves the recovery and reconstruction efficiency of the valve function, and can maintain the structural integrity in repeated contraction-expansion cycles, providing an ideal solution for long-term stable application in a physiological environment.

Systems and methods are provided for an annuloplasty device and delivery system for treating valvular regurgitation. The annuloplasty device (e.g., a transcatheter annuloplasty ring) may include a tube having anterior and posterior anchors that may transition from a constrained state within the tube to a deployed state in which anchors extend through windows of the tube into tissue at the native valve site. Each anchor may include valvular and atrial anchors as well as anchors having different shapes (e.g., a curved anchor and a non-curved anchor). The annuloplasty device may be delivered to the native valve site via a catheter and the annuloplasty device may be manipulated within the patient's heart using a delivery handle to selectively deploy anchors while closing the anterior-to-posterior distance of the valve to treat valvular regurgitation.

The invention belongs to the technical field of medical instruments and discloses a valve leaflet clamping device which comprises a catheter component, a driving mechanism, a first clamping arm, a second clamping arm and an auxiliary clamping component, the driving mechanism comprises a handle assembly and a driving assembly, the driving assembly is connected to the handle assembly and penetrates through the catheter component, the first clamping arm is arranged at the far end of the catheter component, and the second clamping arm is arranged at the far end of the catheter component. The second clamping arm is connected to the first clamping arm, the driving assembly drives the second clamping arm to be opened or closed, the second clamping face of the second clamping arm can make contact with the first clamping face of the first clamping arm, the auxiliary clamping component is assembled on the first clamping arm, and when the second clamping arm is opened, the driving assembly drives the auxiliary clamping component to move towards the second clamping arm. The auxiliary clamping part of the auxiliary clamping component can abut against the second clamping face. By applying the technical scheme, the problems that in the heart valve leaflet repairing operation, when a native valve leaflet is clamped, due to the fact that the native valve leaflet is prone to slipping, clamping is difficult, operation is repeated, the operation time is prolonged, and the operation risk is increased are solved.

The invention provides a valve system which comprises a valve prosthesis and a conveyor, the valve prosthesis has a conveying state and a working state, in the conveying state, the valve prosthesis is compressed in the conveyor, in the working state, the valve prosthesis is completely released from the conveyor, the valve prosthesis comprises an inflow end and an outflow end, and the valve prosthesis comprises a support body and a clamping piece. The clamping piece is used for clamping the native valve leaflet, the clamping piece is arranged on the outer side of the support body in a sleeving mode, the native valve leaflet is fixed between the support body and the clamping piece, the clamping piece comprises a first connecting position, a second connecting position and a third connecting position which are arranged in the circumferential direction, and the first connecting position, the second connecting position and the third connecting position are all arranged on the side, close to the outflow end, of the clamping piece.

A delivery device can deploy a heart valve prosthesis within a patient's native aortic valve. The valve prosthesis includes a self-expanding lattice frame coupled to a sinus locator. The delivery device includes a sheath configured to maintain the sinus locator in a collapsed position during advancement toward the native aortic valve sinus. The sheath can be proximally retracted relative to the sinus locator to permit partial radial expansion of a distal portion thereof to permit engagement of the sinus locator with the native aortic valve sinus. Thereafter, a tubular member, positioned distal to the sheath and holding the lattice frame in a collapsed position, can be distally advanced relative to the lattice frame to expose and permit expansion of the lattice frame. The expansion of the lattice frame within the sinus locator can thereby sandwich the native valve leaflets between the expanded lattice frame and the sinus locator.