156 results about "Native valve" patented technology

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

A valve device comprises a valve body with a framework and a valve portion coupled to the framework that is movable between open and closed positions. The framework comprises a plurality of wire portions. The valve portion may be formed of a material that promotes in-growth of native tissue so that the valve portion cooperates with native valve leaflets. The valve device also comprises one or more anchors and anchor tethers that secure the valve device in a heart. In some examples, the method includes folding and loading the valve body into a valve cartridge, delivering the valve body through a guide tube to a position the valve body at a target positioned within the heart, pushing the valve body out of the guide tube, and secure the anchors and anchor tethers in the heart, and cutting the anchor tethers to remove excess portions.

An implantable device or implant is configured to be positioned within anatomy such as a native heart valve to repair the valve. The implantable device or implant is configured to be attached to one or more portions of the anatomy or native heart valve, such as one or more portions thereof can be moved closer together. For example, native valve leaflets, chordae tendinea, papillary muscles, a leaflet cleft, etc. can be moved to prevent or inhibit regurgitant flow through the native valve.

An implantable prosthetic device has a coaption element, a pair of paddles, and at least one cover. The coaption element is configured to be positioned within the native heart valve orifice to help fill a space where the native valve is regurgitant and form a more effective seal. The cover can at least partially cover the coaption element and / or the pair of paddles. The cover is at least partially closed by alternating in and out stitches that are substantially unexposed when the cover is secured on the device.

The invention relates to a heart valve docking device and a system for treating a native valve of a patient. In various embodiments, the device is configured to repair a native heart valve or to secure a prosthetic heart valve within a native valve of a patient's heart. An embodiment of the apparatus includes at least an upper coil and a lower coil, wherein the apparatus is configured to assume an axially expanded state in which the entire upper coil is positioned on a first side of the lower coil relative to the central axis and an axially compressed state in which at least a portion of the upper coil is positioned on a second side of at least a portion of the lower coil opposite the first side relative to the central axis.

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

Systems, apparatus, and methods for axially aligning a prosthetic valve with a native valve to achieve implantation at a desired or selected deployment position. A delivery apparatus can include a shaft and a balloon on a distal end portion of the shaft. A prosthetic valve can be radially compressed around the balloon in a valve mounting portion of the delivery apparatus. The delivery apparatus can include a radiopaque marker array attached to the shaft in the valve mounting portion of the delivery apparatus. The markers in the marker array can be sized and spaced from adjacent ones of the markers such that they define locators in the array that are indicative of a plurality of deployment positions, and each locator can be aligned relative to a portion of a host structure to result in the prosthetic valve being implanted at a respective one of the deployment positions.

Docking devices for securing a prosthetic valve at a native valve are provided. The docking device can include a coil and a guard member. The coil includes a plurality of helical turns when in a deployed orientation. The guard member may be attached to the coil by being coupled to at least a portion of a helical turn thereof. The docking devices include a atrial functional turn configured to enhance the transient stage stability of the docking device in the left atrium of the heart.

A catheter assembly for retaining a prosthetic valve as the prosthetic valve is guided to a point of delivery within a patient is provided with radioscopic markers. The markers are distributed within the catheter assembly such that an observer may discern a rotational orientation of the assembly from a radioscopic image of the assembly within the patient. Delivery of the prosthetic valve may include aligning the markers with the commissures of the prosthetic valve and radioscopic observation of the location or movement of the markers to rotationally align the prosthetic valve with a native valve within the patient, such as by aligning the commissures of the prosthetic valve with the commissures of the native valve.

A valve repair device, e.g., for treating mitral valve regurgitation, includes a tubular body defining a longitudinal axis, paddles supported by the tubular body and movable to change abduction of the paddles relative to the longitudinal axis, and retention members supported by the tubular body proximal the paddles and similarly movable to change abduction of the retention members relative to the longitudinal axis to facilitate capture of native valve leaflets between pairs of paddles and retention members. Movement of the paddles and / or retention members is provided by one or more control mechanisms including a collar a shaft extending within the tubular body. Each shaft is threadedly engaged to a respective collar and coupled to one or more of the movable elements such that, when the collar is rotated, the shaft translates to change abduction of the movable element relative to the longitudinal axis.

A capsule of a delivery system for a transcatheter heart valve prosthesis includes markers for rotationally orienting the capsule within a native valve. The capsule includes markers that are sized and located on the capsule such that when viewed in a cusp overlap viewing angle image, the markers indicate whether the capsule is in a desired rotational orientation. Methods for rotationally aligning a capsule of a delivery system containing a transcatheter heart valve prosthesis within a native valve are also provided.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

A prosthetic tricuspid heart valve system includes a collapsible anchor frame and a collapsible prosthetic heart valve. The anchor includes a support structure having a waisted central portion, and atrial and ventricular flared portions sized to clamp a native valve annulus. Atrial and ventricular sheets are coupled to the atrial and ventricular flared portions, and each include a central aperture. A generally cylindrical fabric valve-receiving member has an inflow end coupled to the atrial sheet and an outflow end coupled to the ventricular sheet to provide a conduit through the valve-receiving member between the atrial and ventricular sheet. The prosthetic heart valve may include a stent and a plurality of prosthetic leaflets, the prosthetic heart valve configured to be expanded into and received within the valve-receiving member of the anchor frame.

The application provides a valve anchoring device, a guide device and a method for anchoring a prosthetic valve, mainly comprising an anchoring structure and a positioning member, wherein the anchoring structure has a first anchoring member and a second anchoring member extending from both sides of a combination member, the positioning member is connectable to the combination member, the combination member passes through a commissure of a leaflet of a heart tissue, the positioning member is positioned at one side of a heart atrioventricular valve adjacent to an atrium, the first anchoring member and the second anchoring member are positioned at one side of the heart atrioventricular valve adjacent to a ventricle, and the first anchoring member and the second anchoring member are cooperatively matched to anchor the prosthetic valve, so that the prosthetic valve is positioned relative to a native valve of the heart tissue. Therefore, the anchoring effect of the prosthetic valve can be improved.

A device is provided for securing a prosthetic valve at a native valve. The docking device can include a coil comprising a plurality of helical turns when in a deployed orientation. The docking device can include a compressible plug attached to the coil by being coupled to at least a portion of a helical turn thereof. The compressible plug is movable between a radially compressed state in a delivery orientation and a radially expanded state in the deployed orientation. The compressible plug includes: a compressible scaffold formed from a shape-memory material; and a plugging component operably coupled with the compressible scaffold to provide a liquid plugging function to the compressible plug.

The present invention relates to an atrioventricular heart valve prosthesis implantable, for example, into the heart of a mammal. The heart valve prosthesis comprises a collapsible-expandable tubular stent having a lumen, preferably having an opening cross-section or area during use or in a fully expanded state of the stent that is smaller than an opening area of a native atrioventricular heart valve to be replaced by the heart valve prosthesis. The heart valve prosthesis further includes an inner valve tip disposed within the lumen of the tubular stent that closes the heart valve by resting against each other, an outer valve leaflet that closes against the native valve leaflet, and at least one anchor wire connected directly or indirectly to the tubular stent. The invention also relates to a method for manufacturing a heart valve prosthesis and to a method for inserting a heart valve prosthesis.

To provide methods and apparatuses for bisection of heart valve leaflets using a catheter having a cutting element.SOLUTION: The invention is a device, system, and method for repairing the heart valve function, which may include bisecting native valve leaflets for improved deployment of a prosthetic heart valve in the native valve annulus. The invention may include a catheter having a cutting element shaft with a cutting element configured to puncture a valve leaflet and / or make a controlled cut through the leaflet. The device may have an extendable foot configured to be positioned on an opposite side of the valve leaflet from the cutting element shaft. The device may include magnets to guide the cutting element and / or cutting element shaft in proper alignment with the extendable foot and to hold the elements in place during leaflet bisection.SELECTED DRAWING: Figure 7

The application relates to the field of medical devices, in particular to a prosthesis capable of treating valve regurgitation, comprising a radially expandable stent body, the stent body comprising a plurality of diamond-shaped meshes, and at least three clamping members arranged at the outflow end of the stent body, used for positioning the aortic sinus and clamping the native valve leaflets; a sealing bag bulging outward is arranged on the stent body between adjacent clamping members, wherein the position of the sealing bag corresponds to the junction area of the aortic valve leaflets, and the sealing bag is attached to the tissue of the junction area of the aortic valve leaflets, and the configuration of the sealing bag is configured to guide the regurgitant blood to flow to the adjacent aortic sinuses on both sides when the blood regurgitates; in the application, the sealing bag guides the regurgitant blood to flow to the adjacent aortic sinuses in a diversion manner, so that blood regurgitation is avoided, and meanwhile, when the aorta pumps blood again, the blood in the aortic sinus is ejected, so that blood stasis is avoided.

A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and / or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.

The utility model relates to the technical field of medical instruments, in particular to an artificial valve clamping piece and a conveying system. The artificial valve clamping piece comprises a clamping piece body, a connecting wire and a traction structure, the clamping piece body comprises a pipe body and a plurality of through holes formed in the pipe body, the pipe body is in a wave shape, and the two ends of the pipe body are closed to form a ring shape; the connecting wire penetrates into the tube body, and the end part of the connecting wire penetrates through the through hole in the tube body and then is suitable for being connected with the artificial valve; the traction structure comprises a traction wire, the traction wire is arranged in the pipe body in a penetrating mode through a through hole in the pipe body, and the traction wire is suitable for being connected with a conveying system. The clamping piece is of a periodic wave-shaped or fluctuating annular structure, can be fixed to the periphery of the outer surface of the artificial valve, can be radially compressed and expanded according to the size of the internal artificial valve, and is matched with the artificial valve to clamp the autologous valve leaflet, so that the artificial valve can be stably anchored at an accurate position without displacement, and meanwhile, the clamping piece can be used for clamping the autologous valve leaflet. The clamping device can reduce the occurrence risk of perivalvular leakage.

This disclosure relates to an artificial heart valve for replacing a natural heart valve, comprising: an annular stent including: a mesh structure serving as a circumferential sidewall of the stent; and a leaflet structure, each leaflet being attached to the stent and having a first portion disposed within the stent and a second portion rolled up to the proximal peripheral side of the stent. As the heart grows, the stent can be expanded after the artificial heart valve is anchored to the heart, thereby allowing the artificial heart valve to function in different states without replacement. The edge end of the second portion of each leaflet is connected to the stent at a location between the distal and proximal ends of the stent, but not fixed to the proximal end of the stent. In at least one state, the size of each leaflet exceeds the fit size of the stent in that state, and each leaflet has a redundant portion that hangs freely from the distal to the proximal end to a location away from the stent, thereby allowing the leaflet to be sized away from the stent to form a more functional valve.

Provided are an artificial intelligence AI-based simulation device and method for supporting procedure planning in transcatheter aortic valve implantation. The device receives patient-specific medical images, such as computed tomography data, and generates a three-dimensional (3D) model of the aortic root and native valve. An artificial valve is virtually inserted into the 3D model, and the virtual implantation model is automatically converted into mesh data suitable for Computational Fluid Dynamics (CFD) and Fluid-Structure Interaction (FSI) analysis. The processor performs CFD / FSI simulations to evaluate hemodynamic changes, structural stresses, and potential device-tissue interactions. Based on the analysis, the system outputs predicted risks of procedure-related complications (including coronary obstruction, annular rupture, paravalvular leakage, and valve deformation) and provides guideline data for selecting valve size, implantation depth, and insertion angle. The disclosed device and method enable accurate, patient-specific prediction and visualization, thereby assisting clinicians in establishing safe and optimized TAVI procedure plans.

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device with an elevated valve section and comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and / or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed.

Apparatuses and methods are described that include a delivery device that delivers a valve frame (120) to a native mitral valve and positions the valve frame (120) such that the center of the valve frame (120) is off-centered with respect to the center of an annular plane of the annulus and is positioned towards a posterior side of the annular plane. The arms (124) of the valve frame (120) are deployed between chordae tendineae of the native mitral valve. The valve frame (120) is rotated to cause the arms (124) to pull the leaflets of the native valve radially inward. The frame body (121) of the valve frame (120) expands radially to capture the native leaflet and cause the valve frame (120) to be deployed off-center with respect to the center of the annular plane. Other applications are also described herein.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

A heart valve prosthesis can be delivered within a native heart valve annulus using a delivery system that encases the heart valve prosthesis and sequentially permits expansion of a valve clasper and a lattice frame of the valve prosthesis. A sheath of the delivery system can be proximally retracted to permit the sinus locator to expand. Thereafter, a tubular member can be actuated to permit expansion of the lattice frame. Further, a clasper pusher of the delivery system, coupled to the tubular member, can be used to release a proximal portion of the sinus locator after release of the lattice frame. The delivery system can enable sinus locator engagement within the native annulus, sandwiching native valve leaflets between the expanded lattice frame and sinus locator, and thereafter permit disengagement of the sinus locator from the clasper pusher after the lattice frame expands.

A docking device for securing a prosthetic valve at a native valve includes a coil having a plurality of helical turns when deployed at the native valve and a guard member attached to the coil. The guard member is movable between a radially compressed state and a radially expanded state. The guard member includes a plurality of flaps. Each flap includes a rounded head portion and a tapered base portion. The head portion is wider than the base portion when the guard member is in the radially expanded state.

comprising a working catheter (3) and at least one tool being configured to slidably move through the working catheter (3); characterized by the fact that said tool is an expandable stent (26) configured to allow an opening of an aortic native valve, the stent (26) furthermore comprising an ultrasonic transducer (25).

A delivery system includes a delivery sheath with a control device and at least one supra-annular support being movable through a lumen of the delivery sheath. The control device includes a connection member coupled to a distal end of a control catheter. The connection member is configured to removably couple to the prosthetic valve at a proximal position along a supra-annular portion of the prosthetic valve. The control device is operable to advance the prosthetic valve in a compressed configuration through the delivery sheath and to at least partially deploy the prosthetic valve in an expanded configuration into a native valve annulus. The supra-annular support(s) is / are removably coupleable at one or more positions along the supra-annular portion of the prosthetic valve and is / are configured to stabilize or actuate at least a portion of the prosthetic valve relative to an annular plane of a native heart valve during deployment.