456 results about "Native valve" patented technology

A heart valve prosthesis for replacing a diseased native valve in a patient. The valve prosthesis includes a compressible and expandable frame structure and an anchor connected to an outer periphery of the frame structure. The anchor comprises a helical wire having a free end. The valve may further include a valve segment mounted within the frame structure and expanded with the frame structure. The frame structure may be configured for receiving a valve segment.

A device for treating a diseased native valve in a patient is provided, the device including a frame structure and a plurality of leaflets. The device can further include a spiral anchor configured to extend around an outer circumference of the frame structure. The anchor can be configured to deliver a contrast agent into or near a target tissue. Other embodiments and methods of use are also provided.

A polymeric mitral heart valve, comprising: valve leaflets (3), a valve stent (1) and a valve ring (2), wherein the valve stent (1) is of a hollow columnar structure, the valve stent (1) comprises a first end (11) and a second end (12), the first end (11) is provided with three column peaks (13) spaced apart in the circumferential direction and column valleys (14) are correspondingly formed; the valve ring (2) is arranged at the periphery of the second end (12) of the valve stent (1), two protruding sections (21) extending towards the first end (11) in the axial direction are formed at the periphery of the valve ring (2) to be capable of corresponding to two of the column peaks (13), and a flat section (22) is formed at a position corresponding to the other column peak (13); the valve further comprises an insert (5), the insert (5) is of a hollow columnar structure matching the valve stent (1), and the insert (5) is suitable for being embedded in the valve stent (1) in the axial direction; the valve leaflets (3), the valve stent (1) and the valve ring (2) undergo one-time injection molding, and the insert (5) is embedded in the valve stent (1) during injection molding to form a whole. By optimizing the structures of the valve ring (2) and the valve stent (1), the adaptability of the valve ring (2) to a native valve ring is improved, the radial support force of the valve stent (1) is improved, and the valve performance is optimized.

An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The device can be deployed from a delivery system including one or more lines which can be decoupled from the device by energizing. The device can include contoured clasps which approximate the shape of the native valve when the clasps are in the closed position. The device can include a coaptation element with body portion including a plurality of struts and openings defining a lattice structure. One or more surfaces of one or more components of the device can be coated to improve the visibility of the device during deployment and implantation.

The present disclosure provides systems and methods for a replacement mitral valve. The replacement valve may be made of a less rigid material thereby allowing the packed diameter of the replacement valve to be decreased. The less rigid replacement mitral valve may include a ventricular portion and a central portion. The ventricular portion may include a guide channel. A wire may be advanced into the guide channel. The wire in the guide channel may increase the stiffness on the ventricular side of the replacement valve. The increased stiffness may prevent the replacement valve from collapsing through a native valve annulus.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

A device configured to be positioned within a native heart valve to repair the valve. The device includes a leaflet pinching or capturing mechanism to capture a first leaflet and second leaflet of the native valve and then attach the first leaflet to the second leaflet. The device includes a first surface and a second surface, wherein the first surface and the second surface are movable between an open condition and a closed condition to pinch a first leaflet and a second leaflet of the native valve therebetween. Once the first and second leaflets are captured, portions of the leaflets are fused together, adhered together, or fused and adhered together. In some implementations, a system is configured to access a papillary muscle and ablate tissue of the papillary muscle to disable a conductive pathway to the papillary muscle.

The present application relates to the field of medical devices, and specifically to a repair device for preventing valve regurgitation, comprising a mounting bracket, a single anti-reflux prosthesis for replacing the function of a single native valve leaflet, and a fixing member, wherein one end of the single anti-reflux prosthesis is fixed on the mounting bracket, and an atrial segment is provided at the distal end of the mounting bracket, and the atrial segment is configured to adapt to the morphology of the native valve ring tissue, and the atrial segment includes a leak-proof portion, and the proximal end portion of the mounting bracket is anchored in the ventricle by the fixing member, wherein, after the mounting bracket is installed in place, the leak-proof portion abuts against or fits the native valve ring tissue, and when the native valve opens and closes so that the morphology of the native valve ring changes, the leak-proof portion follows the morphological change of the native valve ring and produces adaptive deformation, so that the leak-proof portion always abuts against or fits the native valve ring tissue.

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and / or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and / or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

A method of delivering and deploying a valve prosthesis includes delivering the valve prosthesis disposed in a delivery catheter to a native valve, proximally retracting a delivery catheter tube of the delivery catheter such that three engagement arms of a support of the valve prosthesis are released from the delivery catheter tube and flare outwardly while an inflow frame portion of the support remains within a distal portion of the delivery catheter, and distally advancing the distal portion of the delivery catheter such that the inflow frame portion is released from the distal portion.

A device for treating a diseased native valve in a patient is provided, the device including a frame structure; a valve segment positioned radially within the frame structure, the valve segment comprising a plurality of leaflets, and a plurality of commissure attachment mechanisms coupling the leaflets to the frame structure, each commissure attachment mechanism extending radially inwards from an outflow end of the frame structure as to create a gap between an interior diameter of the outflow end and an outflow edge of the valve segment. Other embodiments and methods of use are also provided.

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame. The prosthetic heart valve further having systems for anchoring the upper flared portion of the stent to a posterior portion of the native valve annulus.

An device for treating a native valve includes a sealing element and an anchoring element. The sealing element is made from a braided mesh material. The sealing element is dimensioned to be deployed in an annulus of a native valve of a heart at a position between native valve leaflets to contact the native valve leaflets during ventricular systole to create a seal to prevent regurgitation of blood from the left ventricle to the left atrium. The sealing element is configured to both be radially expanded and radially reduced while at the position between the native valve leaflets. The anchoring element is adapted for deployment in the heart, the anchoring element coupled to the sealing element and configured to support the sealing element at the desired position between native valve leaflets.

A method of retrieving a previously implanted device from a native valve of a patient's heart includes attaching the retrieval device to the previously implanted device. An actuation member can engage the previously implanted device to move the previously implanted device from a closed configuration to an open configuration. A clasp capturing member can attach to a clasp of the previously implanted device.

Delivery systems, devices, and methods for delivering a valve prosthesis to a native valve annulus are provided. The valve prosthesis may be secured to the native valve via an anchor that encircles the native valve annulus and the valve prosthesis. The anchor may be deployed around the chordae tendinea and / or leaflets of the native valve. A tether may be connected to the anchor and extend outside of the patient's body to maintain communication with the anchor. After the anchor is deployed, a guidewire may be advanced through the patient's vessels parallel to the tether and through the native valve annulus. A valve delivery catheter carrying the valve prosthesis may be advanced over the guidewire and into the native valve annulus where the valve prosthesis is released and deployed. The tether may be used to position the anchor and / or valve prosthesis during one or more operations of the valve delivery process.

Systems and methods usable in delivering an anchoring or docking device to a native valve of a patient's heart. A distal region of a delivery catheter can be positioned in an atrium of the heart and a. distal tip can be positioned at or near a commissure of the native valve using a steerable sheath. The one or more bends can be generated and / or adjusted in a distal portion of the steerable sheath to manipulate the position of the distal tip of the delivery catheter.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

A fixation device for fastening to a native heart valve having native valve leaflets, the fixation device comprising: (a) a device body, and (b) at least one clamp on the device body, the clamp for engaging and holding a native valve leaflet, the clamp comprising at least one moveable jaw, the moveable jaw having thereon at least one gripping element which is moveable relative to the moveable jaw between a native valve leaflet gripping configuration of the moveable jaw where the gripping element is arranged to grip a native valve leaflet and a passive configuration of the moveable jaw where the gripping element is arranged so that it cannot grip a native valve leaflet. This provides a device that can be repositioned during a medical procedure.

The utility model provides a valve stent and an artificial heart valve prosthesis, the artificial heart valve comprises the valve stent, the valve stent is provided with an inflow end and an outflow end which are opposite to each other, and the valve stent comprises a main stent and a plurality of clamping mechanisms which are arranged at intervals along the circumferential direction of the main stent and are connected with the outer circumferential surface of the main stent; the clamping mechanism comprises a first clamping body and a second clamping body which are arranged in the direction from the inflow end to the outflow end. The first clamping body and the second clamping body are used for clamping the native valve leaflet so that the heart valve prosthesis can be anchored in the heart, the anchoring of the heart valve prosthesis can be achieved without extruding the valve ring in the radial direction through the main support, and the situation that native tissue such as the valve ring is damaged due to radial extrusion is avoided.

Disclosed are numerous embodiments of selective occlusion devices (SODs) that can be disposed in native heart valves in conjunction with leaflet clips to remediate regurgitation of the native valve.

A valve repair system for repairing a native valve of a patient includes a catheter and a valve repair device. The valve repair device is disposed in the catheter. The valve repair device comprises a compressible spacer and a pair of paddles. The pair of paddles are moveable between an open position and a closed position. The valve repair device can transition to a compressed configuration with the compressible spacer between the pair of paddles in the closed position.

A valve repair device for repairing a native valve of a patient. The valve repair device having one or more adjustable width paddle frame portions. The adjustable width paddle frame portions having an anterior portion extending from the medial side of the device to the lateral side of the device and a posterior portion extending from the medial side of the device and a lateral side of the device opposite the anterior portion. The anterior portion and the posterior portion are formed as a single frame member integrally joined at linking portions at the medial side of the device and a lateral side of the device. A connector includes attachment portions that connect to the linking portions to attach the adjustable width frame portion to the connector.

An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The clasps include a fixed arm and a plurality of movable arms. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve.

The present application relates to the field of medical devices, and specifically to an aortic valve auxiliary prosthesis for preventing regurgitation, comprising: a main body, which is configured to remain in place in the aorta at the surgical site; and three auxiliary leaflet segments configured to cooperate with the three free segments of the native leaflets of the aortic valve; the three auxiliary leaflet segments are fixed to the main body. The present invention allows the original native leaflets to be retained, and when the native valve is closed, the purpose of improving the prevention of regurgitation is achieved by overlapping and covering the free segments of the native valve, with significant therapeutic effects and stronger targeting. Since the native valve is retained, most of the impact force of blood when flowing is still on the native valve, the reliability requirements for the fixed positioning of the main body are low, and the morphological changes to the native valve are smaller.

The present disclosure relates to methods of treating a patient that has a low coronary ostia height. The methods can involve advancing a heart valve prosthesis to a native valve structure having an ostium and positioning the prosthesis to align a gap between major peaks of the prosthesis with the ostium to avoid obstruction of the ostium. The presently disclosed methods and prostheses can be effective at treating patients with a coronary ostia height of as low as 10 mm, 8 mm, 6 mm, or less.

A prosthetic heart valve includes a multi-part frame having a first annular body and an anchor component that includes a second annular body circumscribing the first annular body. The first annular body includes a plurality of struts arranged in a lattice pattern and defining a lumen. The anchor component further includes one or more ventricular anchors extending from the second annular body toward an inflow end portion of the first annular body. A fabric layer is disposed on an inner surface of the first annular body and sutured to the struts. A valve structure including three leaflets is disposed within the lumen and inlet ends of the leaflets are sutured to the fabric layer. The multi-part frame is radially compressible for delivery within a sheath of a delivery catheter and is self-expandable for deployment within an annulus of a native valve.

A prosthetic device for treating a native valve of a heart includes a sealing element and an anchoring element. The sealing element comprises a braided mesh material. The sealing element is dimensioned to be deployed at the native valve. The sealing element is configured to both be radially expanded and radially reduced while at a position between the native valve leaflets. The anchoring element is coupled to the sealing element and is configured to support the sealing element between the native valve leaflets.

The present invention provides a prosthetic heart valve, including a stent, prosthetic leaflets and an occlusion mechanism. Both the prosthetic leaflets and the occlusion mechanism are connected to the stent. The occlusion mechanism is able to extend outwards away from the stent and fill up a recessed portion of a native valve annulus, thereby closely fitting the prosthetic heart valve against the native valve annulus and effectively preventing paravalvular leakage.

A valve repair device and valve repair systems including a delivery device and a valve repair device for repairing a native valve of a subject. The valve repair device and / or the delivery device having one or more force measurement devices for detecting a force applied to the native valve of a subject due to the connection between the valve repair device and the native valve.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to the anatomy at the site of the native heart valve. Such structural features can provide robust migration resistance. In addition, the prosthetic heart valves can include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate paravalvular leakage. In particular implementations, the prosthetic heart valves occupy a small delivery profile, thereby facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems can include a curved inner catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.