113 results about "Valve replacement" patented technology

Disclosed are valve replacement devices, systems, and methods. Valve replacement devices may comprise one- or two-piece systems comprising a receiver body (also called an adapter) and a valve assembly with replacement leaflets attached to and located within the receiver body. In two-piece systems, the valve assembly may be removable from the receiver body such that both can be delivered together or separately, and the receiver body may remain implanted while the valve assembly may be removed and replaced. Also described are devices, systems, and methods related to delivering, removing, and replacing a valve replacement. Such delivery methods may include transseptal insertion of a new minimum leaflet structure, and securement of the valve replacement using several securement type (e.g., supra-annular, sub-annular, radial, leaflet securement, etc.). Also described is a braided helical design that mimics the heart's natural movement, and a flange structure for assisting the functioning of the valve replacement.

The invention relates to an artificial heart valve and a transcatheter heart valve replacement system.The artificial heart valve comprises a valve support and an outer skirt part, the valve support is provided with an inflow end and an outflow end, and the valve support is sequentially provided with a plurality of grid sets arranged in the circumferential direction from the outflow end to the inflow end; wherein the grid group closest to the inflow end is suitable for being matched with the position below the annulus plane, and the size of a net opening of at least one non-end grid group matched with the annulus plane is larger than that of a net opening of at least one axially adjacent grid group; the outer skirt part covers the outer surface of the valve stent, the outer skirt part at least covers the two adjacent grid groups close to the inflow end, and the position, close to the inflow end, of the outer skirt part is configured to be of a structure with the thickness gradually increased in the direction from the outflow end to the inflow end.

Example valve replacement devices and methods of using valve replacement devices are disclosed. An example device includes a framework including a plurality of strut members forming a proximal anchor region. The proximal anchor region includes a plurality of distal crowns and a first connector crown positioned along a distal end of the proximal anchor region. The device further includes a first commissure assembly coupled to the distal end, wherein the first commissure assembly includes a first commissure post, a first connector strut and a second connector strut. The device further includes one or more leaflets mounted at least partly within the framework. Further, the first and second connector struts each include a first end attached to the first commissure post and a second end attached to the first connector crown at a first pivot point. Further, the pivot point is positioned radially outward of the plurality of proximal crowns.

Provided is a prosthetic valve replacement system. A hoop member is at least partially disposed on a valve clamping mechanism. A valve clamping and securing mechanism is configured to present a first form and a second form, and the second form is present after the first form. When the valve clamping and securing apparatus is in the first form, the valve clamping mechanism is configured to capture and clamp autologous valve leaflets. After the radial expansion of a valve stent, the valve clamping and securing apparatus is in the second form.

The application provides a heart valve positioning device, which comprises a first curved structure, a second curved structure, and a third curved structure. The first curved structure forms a spiral curved structure with a first size in a released state. The second curved structure forms a spiral curved structure with a second size in a released state, and the second size is greater than the first size. The second curved structure has a hollow first cavity for the first curved structure to pass through, forming the third curved structure. The distal end of the third curved structure is a free end, and the proximal end is connected with a delivery system. The third curved structure forms a spiral curved structure with a third size in a released state, and the first size is less than the third size and less than or equal to the second size. The embodiment of the application can reduce left ventricular outflow tract obstruction caused by large-scale movement of the anterior leaflet.

The invention relates to an anchor hook and methods of using the same for subannular anchoring of a transcatheter heart valve replacement, and in particular for an orthogonally delivered (side-delivered) transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the mitral or tricuspid valve from the inferior vena cava or superior vena cava, or trans-septally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring a delivery catheter to bend 90 degrees during deployment.

Methods, apparatuses, and systems for performing a valve replacement or repair. Apparatuses may include systems and may include an outer catheter, one or more interchangeable inner catheters, a guidewire and an expandable chordae tendinae deflector. Also described herein are rapid pacing sheaths that may be used with any of these apparatuses and methods.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

The disclosure provides a subclinical valve leaflet thrombosis auxiliary identification method, system and signal acquisition device after transcatheter aortic valve replacement, belonging to the technical field of heart information acquisition and identification. The subclinical valve leaflet thrombosis auxiliary identification method is used for auxiliary diagnosis of subclinical valve leaflet thrombosis after transcatheter aortic valve replacement, comprising: collecting a heart sound signal, processing the heart sound signal, obtaining preset parameters of the heart sound signal, and the preset parameters at least including time, frequency and energy; determining a systolic period according to the heart sound signal; identifying the highest energy point in the characteristic interval of the systolic period; obtaining the characteristic frequency corresponding to the highest energy point, and judging whether the characteristic frequency is greater than the threshold frequency, if yes, marking the heart sound signal as an abnormal heart sound signal caused by subclinical valve leaflet thrombosis; if not, marking the heart sound signal as a normal heart sound signal. The method solves the problem that the subclinical valve leaflet thrombosis detection mainly uses multi-dimensional computed tomography, which leads to limited scope of application.

The invention belongs to an atomization device, and provides a miniaturized liquid atomization device and a control method thereof in order to solve the technical problems that an existing cylinder valve is unchanged in replacement, low in safety and incapable of achieving zero leakage. The liquid cavity is communicated with the gas cavity through an on-off device, an atomizer device and a pressure controller in sequence, the gas cavity is communicated with the outside through a switch device and a pressure reducing device in sequence, an outlet of the pressure reducing device is communicated with the outside, and the on-off device, the atomizer device and the pressure controller are integrally arranged between the liquid cavity and the gas cavity. The switching device and the pressure reducing device are integrated at the gas cavity outlet. While the weight is reduced, the leakage risk is greatly reduced.

The application relates to the technical field of gas tree valve replacement maintenance, and discloses a plugging tool for wellhead gas tree pressure-bearing valve replacement without releasing the tool, which comprises a coaxially arranged shell, a limiting sleeve, a second cylinder, a rubber cylinder assembly, a guide shoe, a mandrel, a spring, a first cylinder and a piston. When the valve replacement operation of the gas tree is performed, the plugging tool can be sent into the front-end pipeline of the valve by connecting a feeding and pressurizing device on the shell. In use, the rubber cylinder assembly can be axially compressed and radially expanded by hydraulic pressure, so that the rubber cylinder assembly is tightly sealed with the inner wall of the pipeline. When the pressurizing is stopped and the feeding and pressurizing device is subsequently disassembled, the spring and the rubber cylinder assembly can play a pressure maintaining effect under the action of the spring and the elastic force of the rubber cylinder assembly, so that the reliability of the sealing and plugging is maintained. After the valve replacement is completed, the mandrel can be directly pushed by a rigid member to realize pressure relief and unsealing. The plugging tool can realize pressure-bearing valve replacement operation, has the advantages of reliable sealing, easy unsealing, and relatively simple structure and convenient operation.

The invention relates to constriction devices and methods for deploying a laterally delivered prosthetic heart valve in a native annulus. The present invention relates to anchoring channels and subannulus anchors for transcatheter heart valve replacement (A61F2 / 2412), and in particular for transcatheter prosthetic heart valves with orthogonal delivery of an annulus support frame having a compressible wire unit, the compressible wire unit facilitates rolling and folding of the valve in a longitudinal direction or orthogonal to a central axis of the flow control member, allowing delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve, or trans-atrial delivery and deployment to the mitral valve, or delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve. The valve has a height of about 5 mm to 60 mm and a diameter of about 25 mm to 80 mm without the need for an over-diameter catheter and without the need for delivery and deployment from the catheter at an acute access angle.

A heart valve replacement device comprises a stent having a first end, a second end, an outer surface, and an inner surface, the inner surface defining a lumen; and a valve disposed within the lumen of the stent, the valve formed from a single sheet of tissue, the valve having an outer surface, an inner surface, and a thickness between the outer surface and the inner surface, the valve comprising at least three leaflets, wherein, the valve is attached to the stent with minimal sutures. The leaflets are formed with a curvilinear surface.

The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement, and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

A method of delivering a transcutaneous dual valve replacement (TDVR) device to a patient includes the steps of advancing a guide catheter into the heart of the patient, advancing a support wire through the guide catheter and across the mitral valve of the heart of the patient, removing the guide catheter, advancing a delivery sheath over the support wire and across both the aortic valve and the mitral valve of the heart of the patient, advancing the TDVR device over the support wire and through the delivery sheath, removing the delivery sheath, expanding a first segment of the TDVR device in the mitral valve and a second segment of the TDVR device in the aortic valve, and removing the support wire.

The present invention relates to an anchoring channel and a subannular anchor for transcatheter heart valve replacement (A61F2 / 2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having an annular support frame having a compressible wire unit that facilitates rolling and folding of the valve longitudinally or orthogonally to the central axis of the flow control component, thereby allowing very large diameter valves to be delivered and deployed from the inferior vena cava or superior vena cava to the tricuspid valve, or delivered and deployed transatrially to the mitral valve, the valve having a height of approximately 5 mm-60 mm and a diameter of approximately 25 mm-80 mm, without the need for an overly large diameter catheter and without the need for delivery and deployment from the catheter at an acute approach angle.

A heart valve replacement device comprises a stent having a first end, a second end, an outer surface, and an inner surface, the inner surface defining a lumen; and a valve disposed within the lumen of the stent, the valve formed from a single sheet of tissue, the valve having an outer surface, an inner surface, and a thickness between the outer surface and the inner surface, the valve comprising at least three leaflets, wherein, the valve is attached to the stent with minimal sutures. The leaflets are formed with a curvilinear surface.

The application relates to the field of medical devices, in particular to a valve replacement system facilitating the capture of valve leaflets, comprising a valve support, a delivery system for delivering the valve support, the valve support being provided with a clamping arm, a linkage rod connected with the clamping arm, and an anchoring ring connected with the linkage rod, wherein the distal end of the linkage rod is detachably connected with the distal end of the delivery system, and the delivery system is operated to push or pull the linkage rod to the distal end, the linkage rod drives the clamping arm to fold to control the included angle between the clamping arm and the valve support; in the application, the opening and closing of the clamping arm can be controlled by operating the delivery system, the loading pipe diameter can be reduced, recovery can be realized, and intracardiac adjustment is facilitated, and the application has good clinical significance.

The present application relates to a kind of artificial valve stents and artificial valve prosthesis, artificial valve stent is used in valve-in-valve surgery, it includes: stent body, for accommodating in the original biological valve in body;And at least three positioning support arms, all positioning support arms are arranged in one end of artificial valve stent, and distribute along the circumference of stent body, one end of each positioning support arm is connected with stent body, the other end of each positioning support arm extends to the direction of the other end of artificial valve stent at the lateral exterior of stent body, and is used for clamping original biological valve.Valve-in-valve surgery, the artificial valve stent can be realized stable and reliable anchoring with original biological valve by unique anchoring structure, and it is suitable for the valve-in-valve replacement of double-layer biological valve.

The utility model belongs to the technical field of hydraulic systems, and discloses a novel stacked stop valve which comprises a valve body, and a pressure port P, a port A, a port B and an oil return port T are formed in the valve body. Wherein the ball valve sealing bowls are mounted in the pressure port P, the pressure port A and the pressure port B to support the ball valve ball body; the novel stacked cut-off valve is provided with the port P, the port T, the port A, the port B and the port Y, each port can independently or simultaneously cut off five oil ducts, and overhaul and maintenance are facilitated. The multi-oil-duct control function greatly improves the flexibility and reliability of the system. Scale marks of a screwing head of the ball valve are perpendicular to the cut-off valve when the ball valve is normally open, the cut-off state can be switched only by rotating the ball valve downwards by 90 degrees through a wrench, and space of the left position and the right position does not need to be occupied. By means of the arrangement, the assembling space is greatly reduced, multi-loop installation can be achieved in a small space, and the multi-loop valve is particularly suitable for installation of multiple sandwich valve sets and non-stop oil way cutting off and valve replacing operation.

The invention relates to the technical field of medical data processing, and discloses a heart valve replacement postoperative hemodynamic simulation and curative effect evaluation processing system which comprises the steps that a preset standard artificial valve three-dimensional geometric model is used for replacing a valve area distorted due to metal artifacts in computed tomography data so as to generate a static computational domain grid, the method comprises the following steps: adding a time-varying quantity source item resistance coefficient in a Navier Stokes equation according to a cardiac cycle sequential logic, simulating a valve leaflet opening and closing physical effect under a static grid by adjusting a spatial unit fluid impedance attribute, and resolving a flow field, and establishing a virtual motion mechanism based on a momentum source item to replace complex dynamic grid reconstruction; and the numerical stability and clinical treatment time efficiency of simulation calculation are improved while the geometric boundary fidelity is ensured.

This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

The application discloses a heart valve replacement prosthesis and an outer support thereof, and belongs to the field of medical devices. The outer support comprises an upper top ring, a hemispherical ring support, a contraction transition ring and an inner support fixed section arranged from top to bottom. The hemispherical ring support is a hemispherical support frame for supporting the inner wall of the atrium. The upper top ring is an annular ring formed by connecting the upper vertices of the hemispherical ring support in sequence with flexible material, and is used for abutting against the top of the atrium. The contraction transition ring is a smooth transition curved surface formed by smoothly contracting the bottom of the hemispherical ring support inward, and is used for adapting to the shape of the inner wall of the atrium near the valve annulus. The inner support fixed section is a cylindrical structure extended downward from the bottom of the contraction transition ring, and is used for adapting to the shape of the valve annulus. The application adopts the design features of three-ring fixed type, D-shaped structure, motion isolation and lower flexibility and upper rigidity, forms a unique prosthesis structure matched with the physiological structure inside the atrium, and achieves the technical effects of safe and reliable fixing mode, convenient operation and simple processing.

The application discloses a self-expanding biological valve, which comprises a fixing support, an inflow end support structure, an outflow end support structure and a silica gel suture ring. The fixing support comprises a stretching part which is disconnected after being subjected to an expansion force, and then the valve is automatically expanded at a predetermined position. In the expanded state, the inflow end support structure and the outflow end support structure are outwardly extended in the radial direction relative to the fixing support, and are used for supporting the valve at the predetermined position, continuously exerting outward and / or downward force on the surrounding tissue, and ensuring reliable fixation of the valve. The valve of the application can be used for valve replacement without complicated suture, reduces the operation time, and reduces the risk of postoperative complications. The ingenious design of the valve can realize quick release and reliable fixation of the valve support.

The utility model discloses a valve stent and a valve replacement system, the valve stent comprises an outer stent, the outer stent comprises an atrial stent and a ventricular stent, and the ventricular stent is connected below the atrial stent; the atrial electrode is arranged on the atrial stent, and the atrial electrode is suitable for ablation of nerves in the atrium when powered on; the ventricular electrode is arranged on the ventricular stent, and the ventricular electrode is suitable for ablation of nerves in the ventricular when powered on. Therefore, due to the arrangement of the central atrial electrode and the ventricular electrode of the valve stent, the atrial nerves of a patient can be ablated through the electrified atrial electrode, and the atrium can be timely and effectively defibrillated. Meanwhile, the ventricular nerves of the patient can be ablated through the electrified ventricular electrode, and ventricular defibrillation can be effectively performed in time, so that the ablation efficiency can be improved, and the life safety of the patient can be effectively guaranteed.

The application discloses a kind of left ventricular mass regression risk prediction method after transcatheter aortic valve replacement, belong to postoperative prediction technical field, its purpose is to solve the technical problem that there is no technology in prior art to effectively predict the risk of left ventricular reverse remodeling after mass regression after transcatheter aortic valve replacement.It includes the following steps: obtaining preoperative heart CT image to be predicted;According to the preoperative heart CT image to be predicted, the image-based parameters of epicardial fat are extracted;According to the extracted image-based parameters, calculate the image-based score;According to the image-based score, calculate the risk probability of left ventricular mass regression after transcatheter aortic valve replacement.Using innovative algorithm, the risk value of left ventricular mass regression can be calculated and predicted, and the risk of left ventricular reverse remodeling after mass regression after transcatheter aortic valve replacement can be effectively predicted.

In various embodiments, provided herein are methods, devices and systems to optimize delivery of ring-shaped articles for receiving transcatheter valves or stents. These methods, devices and systems are used to treat patients with valvular diseases. In some embodiments, the device includes at least three cables configured to hold a ring-shaped article having a center hole. The at least three cables are further configured to be anchored to supra-annular tissue at a heart valve peri-annular region. The ring-shaped article is positioned and deployed by means of at least three cables used to embed screws or anchors attached to the ring-shaped article into the supra-annular tissue; this deployed ring-shaped article is configured to receive a replacement heart valve in its inner lumen, thereby acting as a landing zone.

The invention relates to a tricuspid regurgitation control device for an orthogonal transcatheter heart valve prosthesis. The invention also relates to access and occluder devices, in particular heart valve regurgitation drums and optionally closure discs and / or tubular stents, for managing and providing intentional regurgitation levels within transcatheter heart valve substitutes and in particular orthogonally delivered transcatheter prosthetic heart valves, an orthogonal delivery transcatheter prosthetic heart valve has a first inner flow control member / valve, a second inner reflux control member, and an outer annular support frame with a compressible wire unit that facilitates flat folding along the z-axis and compression of the valve vertically along the y-axis or orthogonal to the central axis of the flow control member, the present invention relates to a valvular delivery and deployment system, in particular to a valvular delivery and deployment system, which allows delivery and deployment of very large diameter valves from the inferior or superior vena cava to the tricuspid valve or trans-atrial delivery and deployment to the mitral valve, the valves having a height of about 5-60 mm and a diameter of about 25-80 mm, without extra-large diameter catheters and without delivery and deployment from catheters at acute access angles.

A transcatheter aortic valve replacement apparatus having a bilateral locking function includes a self-expanding stent, a valve skirt, a valve leaflet, an elastic positioning member, and an outflow end release member; a through-hole is defined in the self-expanding stent, the self-expanding stent is provided with an inflow end and an outflow end, and the sidewall of the self-expanding stent is a grid structure; the valve skirt is connected to the sidewall of the through-hole; the valve leaflet is connected to the inner side of the valve skirt, and the sidewall of the self-expanding stent adjacent to the outflow end is defined by a plurality of outflow end grids; the elastic positioning member is provided with a U-shaped portion and connecting arms located at two ends of the U-shaped portion, and the connecting arms are connected to the self-expanding stent or to the outflow end release member, forming first connection points.