180 results about "Prosthetic valve" patented technology

A prosthetic heart valves including an annular frame and one or more detachable outer skirts and methods associated therewith are disclosed. The frame includes a plurality of interconnected struts and one or more outer skirts releasably attached to an exterior surface of the frame. In some examples, an outer skirt is attached to the frame via at least one retaining suture formed by a plurality of stitches looped around a pull suture. Removal of the pull suture from the suture line enables the outer skirt and frame to separate as the stitches are pulled through openings in the outer skirt and remain attached to the frame. Removability of the outer skirt can facilitate improvements in implant and explant procedures of the prosthetic valves, such as, for example, valve-in-valve procedures.

A 3-D honeycomb textile can include a textured yarn. The textile can exhibit a heat-shrinkage rate from about 10% to about 60%. The textile can be configured to reversibly change its dimensions under application of stress. Prosthetic valves can have the disclosed textiles as a sealing member. Additionally, prosthetic valves can the disclosed textiles as cushion materials. In addition, methods of making the disclosed textiles and prosthetic valves are described.

A prosthetic valve includes a radially expandable and compressible frame, a leaflet assembly comprising a plurality of leaflets coupled to the frame, and an outer skirt positioned around an outer surface of the frame. The outer skirt includes a tissue layer and a non-tissue layer. The tissue layer has a fibrous side and a smooth side. The non-tissue layer is coupled to the smooth side of the tissue layer. The outer skirt is positioned so that the fibrous side of the tissue layer faces away from the frame and the non-tissue layer faces towards the frame.

The present disclosure relates to prosthetic valves that can be expanded to selected maximal diameters. In an example, a prosthetic valve assembly comprises a prosthetic valve having an annular frame, one or more expansion control rods disposed radially outward to the frame, and one or more flexible tension members extending circumferentially around the frame, and comprising one or more local loops wrapped around the corresponding expansion control rods. The flexible tension member is configured to radially expand to a first diameter when all local loops are wrapped around the corresponding expansion control rods, and expand to a second diameter greater than the first diameter, when one of the expansion control rod is retracted from the flexible tension member, thereby allowing the corresponding local loop to unravel.

Provided is a prosthetic valve replacement system. A hoop member is at least partially disposed on a valve clamping mechanism. A valve clamping and securing mechanism is configured to present a first form and a second form, and the second form is present after the first form. When the valve clamping and securing apparatus is in the first form, the valve clamping mechanism is configured to capture and clamp autologous valve leaflets. After the radial expansion of a valve stent, the valve clamping and securing apparatus is in the second form.

A device and method of inhibiting and preventing damage to leaflets during the crimping of a prosthetic valve, and / or facilitating the folding of the leaflets during the crimping of a prosthetic valve.

A prosthetic heart valve for the treatment of structural heart disease wherein the prosthetic heart valve includes an expandable frame that a) has an open cell geometry in the frame of the prosthetic heart valve that can be used to reduce delivery system size, b) has high radial strength, c) has improved restoration of the physiologic EOA, d) has lower recoil, e) has little or no longitudinal foreshortening, f) allows for proper placement of the bioprosthetic valve in relation to the native commissures of the valve, h) has symmetrical and cylindrical expansion of the prosthetic valve resulting in lower rates of leaflet thrombosis and structural valve deterioration, and / or i) prevents allergic response and restenosis associated with nickel content.

An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.

The invention relates to the technical field of medical instruments, and discloses a multidirectional multiple rotatable bending-adjustable heart valve delivery system which comprises a delivery handle, a bending-adjustable handle, a balloon tube and a bending-adjustable sheathing canal, and the bending-adjustable handle is arranged at the near end of the delivery handle; the near end of the balloon tube is arranged in the conveying handle, and a balloon is arranged at the far end of the balloon tube; the bending-adjusting sheathing canal is arranged in the balloon tube, and the near end of the bending-adjusting sheathing canal is connected with the bending-adjusting handle; at least two independent cavities are formed in the bending adjusting sheathing canal, and each cavity accommodates one bending adjusting wire; wherein the bending adjusting handle is provided with bending adjusting pieces, the number of the bending adjusting pieces is consistent with that of the bending adjusting wires, the far ends of the bending adjusting wires are fixed to the far ends of the independent cavities, and the near ends of the bending adjusting wires are connected to the bending adjusting pieces. Accurate bending adjustment and flexible control in the artificial valve conveying process are achieved.

Valve positioning structures for use in a prosthetic heart valve delivery apparatus and associated methods. The delivery apparatus can include a balloon coupled to a distal end portion of a shaft and a valve positioning structure can be disposed around the balloon, and a prosthetic heart valve can be crimped around the balloon and the valve positioning structure. The valve positioning structure can include a support structure, such as a frame or a braided wire mesh, which can be coated with a polymeric coating to protect the balloon and the prosthetic valve. In some examples, the polymeric coating is an open-cell polymeric coating. In some examples, the polymeric coating is a closed-cell polymeric coating. In some examples, a webbing portion of the closed-cell polymeric coating spanning across the cells of the support structure can be formed while the support structure is in an at least partially expanded state.

Embodiments include a valve leaflet for an implantable valve device comprising a leaflet body. The leaflet body comprising a free edge configured for coaptation with free edges of one or more other valve leaflets; and a root edge disposed opposite the free edge. The free edge defining an edge profile comprising a peak and valleys disposed on opposite sides of the peak. Other embodiments are also included herein.

The present invention relates to systems, assemblies and methods for estimating prosthetic valve expansion diameter, and in particular, for system and assemblies equipped with at least one sound or vibration sensor configured to provide real-time estimate of prosthetic valve expansion diameter.

A delivery system for delivering a prosthetic valve in a compressed condition over an inner shaft of a catheter. The delivery system includes a tip extending distally from the inner shaft. The tip has a proximal section and an opposite distal section extending to an end of the tip. The proximal section is configured to support an end of the prosthetic valve during loading and delivery of the prosthetic heart valve and includes a first portion, a second portion, and a third portion. The first portion is adjacent the distal section. The second portion is between the first portion and third portion. The third portion is adjacent a proximal end of the tip. An outer diameter of the first portion is greater than an outer diameter of the inner shaft, an outer diameter of the second portion, and an outer diameter of the third portion.

The present disclosure discloses a prosthetic valve including a radially collapsible and expandable support frame having an inflow end, an outflow end and a plurality of rows of cells extending axially between the inflow end and the outflow end. The plurality of rows of cells includes an upper row of cells and a lower row of cells. The upper row of cells, provided at the outflow end, includes interlaced first polygonal cells, two consecutive first polygonal cells including one of a common diamond shaped cell or a rhombus body. The lower row of cells, provided at the inflow end, includes interlaced chevron-shaped second polygonal cells, two consecutive second polygonal cells including one of a common axially extending strut or a common link, which includes a straight strut portion and a diamond shaped cell. A valve-free zone towards the inflow end enables supra-annular deployment of the valve, thereby, providing a higher effective orifice area.

Off-balloon prosthetic valve delivery procedures involving valve positioning structures are disclosed. As one example, a delivery procedure can include crimping a prosthetic valve around a valve positioning structure of a delivery system, wherein the valve positioning structure can be in a first, off-balloon position relative to a balloon of the delivery system, and moving the valve positioning structure in an axial direction to a second, on-balloon position relative to the balloon. The second position can be axially spaced apart from the first position. In the second position, inflating the balloon can be effective to radially expand the valve positioning structure and the prosthetic valve. In this way, the prosthetic valve can be crimped around the valve positioning structure in the off-balloon position to further minimize the crimped profile of the prosthetic valve.

A radially compressible and expandable frame for a prosthetic heart valve assembly includes a plurality of interconnected frame elements forming a plurality of cells, which are arranged in a first circumferential row of cells defining an inflow end of the frame and a second circumferential row of cells defining an outflow end of the frame. An outflow portion of the second row of cells includes a circumferential row of angled frame elements interconnected to each other at a plurality of upper junctions and a plurality of lower junctions. The upper junctions define the outflow end of the frame and the lower junctions point toward the inflow end of the frame. The lower junctions are not connected to other portions of the frame.

The application provides an atrial stent and relates to the technical field of medical devices.The atrial stent comprises a ball cage, a cylindrical stent, a sealing membrane and an artificial valve; the ball cage is supported in an atrium, and a ball cage opening is formed in the bottom end of the ball cage; the cylindrical stent extends from the ball cage opening to the inside of the ball cage; the sealing membrane covers the bottom of the ball cage and the cylinder wall of the cylindrical stent; and the artificial valve is located in the cylindrical stent.In the application, the ball cage is supported in the atrium after surgery, and the structure is stable, so that relative displacement of the ball cage and the original valve cannot be caused by the beating of the heart or the flushing of blood; and the blood in the atrium can flow into the ventricle through the cylindrical stent; the original valve still maintains the original function; the artificial valve and the original valve form a double-valve structure; and the regurgitation caused by the incomplete closure of the original valve during the output of the blood in the ventricle is blocked by the artificial valve, so that the functional defects of the original valve are complemented, and an ideal interventional treatment effect can be achieved.

Embodiments of an implantable prosthetic valve are disclosed. The valve can have an annular frame having a plurality of frame members and a skirt assembly. The skirt assembly can include a laminate having a fabric layer sandwiched between a first covering member and a second covering member. At least one surface of the fabric layer can be exposed at one or more windows in the second covering member. The skirt assembly can be coupled to the annular frame by a suture extending through the fabric layer at the one or more windows and around at least one of the plurality of frame members. Methods for making such an implantable prosthetic valve are also disclosed.

A prosthetic valve assembly includes a radially expandable and compressible annular frame. The frame includes a plurality of interconnected struts including a plurality of inner struts and a plurality of outer struts. The inner struts overlap adjacent outer struts at a plurality of pivot joints. Radial expansion or compression of the annular frame causes the inner struts to pivot relative to the outer struts at the pivot joints. The assembly also includes a valve structure within the frame having a plurality of leaflets that regulate blood flow through the frame. Some struts include recessed portions, and other struts that cross the recessed portions include segments that reside in the recessed portions at the pivot joints. This provides a continuous or flush inner or outer surface of the frame.

Disclosed herein is an implantable prosthetic valve that is configured to substantially reduce vascular nebula formation and / or uncontrolled tissue ingrowth along the implantable prosthetic valve. Methods of making such implantable prosthetic valves are also disclosed herein. Also disclosed herein are kits comprising one or more sutures configured to substantially reduce vascular nebula formation and / or uncontrolled tissue ingrowth along the implantable prosthetic valve.

A delivery assembly constituted of: a prosthetic valve comprising a plurality of intersecting struts, and a delivery apparatus comprising: a handle; a delivery shaft extending distally from the handle; and a flex sensing assembly, comprising: at least one flex sensor coupled to at least one of the plurality of struts; and a control unit in communication with the at least one flex sensor, wherein the prosthetic valve is movable between a radially compressed configuration and a radially expanded configuration, and wherein, responsive to an output of the at least one flex sensor, the control unit is configured to generate a signal indicative of a diameter of the prosthetic valve.

This invention provides a method for predicting the performance of artificial valve stents based on digital twins, comprising the following steps: acquiring the material parameters and geometric characteristics of the valve stent; real-time monitoring of service data of the valve stent under simulated in vitro service; preprocessing the service data; establishing a fatigue mechanical model; establishing model coupling for the fatigue mechanical model, performing reduced-order model analysis, and establishing a dynamically updated digital twin model; using the digital twin model to simulate and calculate the output data of the valve stent, obtaining simulation data of the valve stent digital twin model; comparing the simulation data of the digital twin model with the service data to verify the accuracy of the digital twin model; establishing a remaining life prediction module; establishing a life assessment module, taking the remaining life output from the remaining life prediction model as input, comparing the remaining life with a preset value, and issuing an early warning when the preset value is exceeded. This invention improves the accuracy of predicting the mechanical performance of valve stents.

Prosthetic valves are provided, e.g., for replacing a mitral or aortic valve of a patient, that includes an annular valve body including an inlet end, an outlet end, and one or more valve members for selectively opening and closing a passage between the inlet and outlet ends, a sewing cuff attached around an outer perimeter of the valve body, and a flexible skirt removably attached around the outer perimeter adjacent the sewing cuff. The prosthetic valve may be introduced into a patient's body, positioned adjacent a valve annulus, and the sewing cuff may be secured around a perimeter of the valve annulus. The skirt may be secured to tissue adjacent the valve annulus to further seal the prosthetic valve around the valve annulus, or the skirt may be removed from the valve body, e.g., if the annulus is sufficiently sealed by the sewing cuff.

A valve cover apparatus for use in a medical assembly including a prosthetic valve and a valve delivery apparatus. The valve cover apparatus includes a housing, a chamber disposed within the housing for receiving a prosthetic heart valve in an at least partially expanded state, a tapered surface defining a portion of the chamber, and a lock ring that is axially movable over at least a portion of the housing between a locked position and an unlocked position. The tapered surface is enables loading and / or guiding of the prosthetic heart valve from the chamber of the valve cover apparatus into a delivery sheath of the valve delivery apparatus and transition the prosthetic heart valve to a radially compressed state. The lock ring restricts movement of the valve cover relative to the delivery sheath when in the locked position, and enables movement of the valve cover when in the unlocked position.

A medical device that is adapted for excising a valve leaflet portion of a valve leaflet from a heart valve includes an elongate shaft including a distal region and an inflatable balloon that is secured to the distal region and that is adapted to extend through the heart valve. The inflatable balloon has an outer surface and includes a deflated configuration and an inflated configuration. An electrocautery electrode is disposed relative to the inflatable balloon such that the electrocautery electrode is positioned to excise the valve leaflet portion when RF energy is applied to the electrocautery electrode and the inflatable balloon is in the inflated configuration. In some cases, the heart valve includes an artificial heart valve. In some cases, the valve leaflet includes an artificial valve leaflet.

The application provides a stent of a prosthetic valve, the stent of the prosthetic valve having opposite inflow and outflow sides, comprising: a support part surrounded by a plurality of U-shaped frames, the openings of the U-shaped frames facing the outflow side, the side edges of adjacent two U-shaped frames being adjacent to each other to form a joint column, and the side edges of the adjacent two U-shaped frames meeting at the top end of the joint column; and a ring part being a mesh structure that is radially deformable and located on the inflow side of the support part as a whole, the connection part between the ring part and the support part being at multiple positions and corresponding to the bottoms of the U-shaped frames on the inflow side respectively. The prosthetic valve prepared by using the stent of the prosthetic valve provided by the application can be implanted in the body in a surgical manner, and meanwhile, based on the partial compressibility of the prosthetic valve, the delivery performance is improved, and the surgical incision can be smaller.

The present invention provides a method and apparatus for monitoring the radial expansion of an artificial valve inside a patient's body, and therefore the size of the artificial valve, or a method and apparatus for locking the artificial valve at a desired expansion diameter. [Solution] An embodiment of a prosthetic valve delivery device is disclosed. The delivery device includes a first portion configured to maintain a constant spatial relationship with respect to a first end of the prosthetic valve, and a second portion configured to maintain a constant spatial relationship with respect to a second end of the prosthetic valve during radial expansion of the prosthetic valve. The first portion includes one or more reference radiopaque markers, and the second portion includes an indicator radiopaque marker. At the position of the indicator radiopaque marker relative to one or more reference radiopaque markers, the axial distance between the first end and the second end of the prosthetic valve is measured, indicating the corresponding diameter of the prosthetic valve when it is radially expanded from a radially compressed state to a radially expanded state.

Prosthetic heart valves including a plurality of leaflets coupled to the frame and methods for leaflet attachment. The leaflets are disposed within the frame and configured to regulate the flow of blood through the frame, each leaflet comprising a cusp edge portion having a first central (apex) region and second and third side regions on opposing sides of the first region. The first region is folded and forms an inflow end of the leaflet when coupled to the frame. The side regions are coupled to the frame in an unfolded state. The leaflets can be coupled to the frame via a connecting suture line or an inner skirt.

The present disclosure relates to valves having a multi-part frame and associated resilient bridging features. The disclosed concept relates to a multi-frame prosthetic valve comprising a leaflet frame sub-component and an anchor frame sub-component, wherein the leaflet frame sub-component is not directly coupled to a patient anatomy and is separated from the anchor frame sub-component by a gap or space. An optional connection sheath may be provided to interconnect the sub-components and assist in delivery and deployment of the prosthetic valve. One or more bridging members or annular groove covers are provided to bridge and cover a gap or space between the anchor frame sub-component and the leaflet frame sub-component, such as at the inflow and / or outflow end of the sub-component. Such bridging / covering features may provide smoother flow distribution, reduce the incidence of complications, facilitate perfusion during delivery, assist device nesting during delivery, assist relative sub-component positioning after delivery, or provide any of a variety of additional or alternative functions and advantages.