1255 results about "Heart valve" patented technology

A collapsible and expandable prosthetic mitral valve stent is provided with improved recapture into a distal lumen of a delivery sheath. Various embodiments comprise a valve support within the interior of a stent frame and defining a flow channel therethrough, wherein the top or upstream of the valve support comprises a row, or a plurality, of stent cells that are bent radially inward at least partially over the flow channel. Some embodiments may comprise a recapture assist mechanism, such as an open paddle, attached to one or more of the inwardly bent stent cells and adapted to receive and / or engage a wire to aid in positioning, expansion, recapture and / or implanting the device in a patient's heart chamber.

The invention relates to the field of physiological status real-time monitoring, provides a virtual patient physiological status real-time monitoring method and system based on digital twinning, and is used for solving the problems of non-linear combination deviation and multi-source data synchronization lag of virtual patient physiological status monitoring caused by dependence on a static model and one-way feedback. The method comprises the steps that a valve three-dimensional model is built based on aorta CT data, and a simulation model containing motion conditions is built in combination with a fluid mechanics equation; the blood flow pressure difference and vortex parameters of valve opening and closing are calculated in real time, an optical fiber virtual sensor is embedded in the topological surface of the valve to simulate blood flow deformation, and a valve state mechanical signal is output; parameters and signals are input into a digital twin engine, particle trajectories and refractive indexes are adjusted to generate a visual interface, blood flow velocity-pressure gradient spatio-temporal data are extracted, model boundary conditions are reversely corrected, and valve movement is synchronized with the physiological state of a patient. According to the technical scheme, heart valve movement is simulated in real time, and the real heartbeat rhythm of the patient is automatically matched.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

The invention discloses an artificial biological heart valve device, and relates to the technical field of heart surgeries. Valve leaflets are fixedly mounted on a supporting assembly, so that the valve leaflets are supported and limited; the first edge (supporting wall 42) of the suture ring is used for suturing and fixing with the supporting assembly, and the second edge (suturing wall 41) is used for suturing with the tissue ring; the wall face of the suture ring has extension in the axial direction, so that an axial distance exists between the first edge (supporting wall 42) and the second edge (suture wall 41), the first edge (supporting wall 42) is located outside the ventricle, the wall face of the suture ring supports the supporting assembly in the axial direction, and the supporting assembly is made to be away from the ventricle by means of the extension size of the wall face of the suture ring in the axial direction. By the adoption of the structure, the thickness of the suture ring does not need to be additionally increased, and the axial position of the supporting assembly cannot be affected during suture and tensioning.

An automated system that can be used for prosthetic heart valve manufacturing or suturing procedures. The system can include a first automated fixture that includes an articulating arm and a target device holder. The system can also include one or more additional automated fixtures, which can be configured as one or more suturing arms that include another articulating arm and a needle holder. The first automated fixture can be configured to rotate a target device held by the holder to allow the one or more additional automated fixtures to perform operations such as form sutures on the target device without intervention of a human operator. The system can include a display system configured to display status information of a suturing procedure.

A method can comprise deploying a prosthetic valve with a delivery apparatus, where the prosthetic valve comprises a frame and a rotatable screw connected to the frame, and where the screw comprises a screw head having an annular bore with internal threads. The delivery apparatus is releasably coupled to the screw and can comprise a first shaft and a first head disposed at an end of the first shaft, the first head comprising external threads releasably engaged with the internal threads of the screw head, and a second shaft that is coaxial with and surrounds the first shaft, the second shaft comprising a second head disposed at an end of the second shaft, the second head releasably engaged with an exterior surface of the screw head. Deploying the valve includes radially expanding the prosthetic valve by rotating the screw with the delivery apparatus.

An intravascular blood pump includes a pump housing having an input port and an output port. A relatively short intake cannula may draw blood in through an intake port and deliver the blood to the input port of the pump housing. The intake cannula is relatively short, to prevent excess hydraulic loss. An outflow hose is connected to the output port of the pump housing, so as to convey blood exiting the output port through the outflow hose in a downstream direction to a discharge port, e.g. into an aorta or other blood vessel. Despite the short intake cannula, the outflow hose longitudinally separates the intake port from the discharge port sufficiently so the intake port and the discharge port remain on opposite sides of a heart valve, despite inadvertent longitudinal shifts of the intravascular heart pump.

An obstructing device mountable on a heart valve cusp or leaflet, comprising:an hollow tubular member, comprising:an attachment element configured to trap said leaflet or cusp comprising:a peripheral frame having a distal end, a proximal end and two side arms;a clipping arm extending distally from said proximal end, located between said side arms and having a free end, so that said cusp or leaflet can be trapped between said frame and said clipping arm;wherein said hollow tubular member is attached to said peripheral frame;wherein said peripheral frame and said central arm are each elastically deformable and have a preferred bending plane to apply clamping force towards said leaflet or cusp when said leaflet or cusp is trapped therebetween; andwherein said peripheral frame and said central arm are each curved in their respective preferred bending plane.

A flexible delivery catheter can be used to deploy valve repair and replacement devices at an implant site for the repair or replacement of poorly functioning native heart valves. Such a catheter can include a flexible tube having a plurality of links. A control wire can be connected to the plurality of links, such that applying tension to the control wire causes the flexible tube to bend.

A delivery apparatus can include one or more actuator assemblies extending from a handle. Each actuator assembly can include an outer sleeve and an actuation member extending having an engagement portion configured to releasably couple an actuator of a prosthetic heart valve. The engagement portion can include a driver head comprising an engagement element configured to engage a corresponding engagement element in a head portion of the actuator, and a gripper member comprising a plurality of arms configured to releasably couple the head portion of the actuator. Each arm can have a distal end portion having a circumferential width wider than a circumferential width of a proximal end portion and an arcuate sectional shape. Rotation of the actuation member in a first direction can radially expands the prosthetic heart valve and rotation of the actuation member in a second direction can radially compress the prosthetic heart valve.

A heart valve prosthesis for replacing a diseased native valve in a patient. The valve prosthesis includes a compressible and expandable frame structure and an anchor connected to an outer periphery of the frame structure. The anchor comprises a helical wire having a free end. The valve may further include a valve segment mounted within the frame structure and expanded with the frame structure. The frame structure may be configured for receiving a valve segment.

A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including a plurality of leaflets is disclosed. As one example, a prosthetic heart valve includes a frame; a plurality of commissure support elements, each connected the frame and including two axially-extending members spaced apart from one another to form a window; and a plurality of leaflets, each leaflet comprising a body and two opposing commissure tabs, each commissure tab arranged adjacent to another commissure tab to form a pair of commissure tabs that are disposed in a commissure support element to form a commissure. Each commissure tab includes a series of overlapping layers that include a first set of two overlapping layers that extends through the window and a second set of two overlapping layers that extends away from the first set of two overlapping layers and over an outer side of a corresponding axially-extending member.

Embodiments are described herein that relate to prosthetic heart valves, and devices and methods for use in the delivery and deployment of such valves.

An assistance system that can be used for prosthetic heart valve manufacturing or suturing procedures includes an automated fixture that can comprise an articulation arm and a target device holder. The target device holder can be positioned and oriented to reduce operator strain during a manufacturing or inspection process. The assistance system includes a user input device enabling the operator to move between positions to assist in such processes. The assistance system can also be trained by capturing sequences of position data corresponding to a manufacturing or inspection process.

The present disclosure relates to the technical field of medical devices, and in particular to catheter implant systems and included associated device, prosthetic heart valves and method. The interventional delivery system included includes a catheter assembly and a control handle connected to the catheter assembly, the catheter assembly has opposing distal and proximal ends and includes an inner sheath and an outer sheath slidably engaged with each other, the outer sheath includes a loading section and a sheath section in sequence from the distal end to the proximal end, the loading section is configured to enclose and keep the interventional device in a compressed state; the control handle includes a main handle and an auxiliary handle slidably fitted over the inner sheath, the proximal end of the inner sheath is connected to the main handle and the proximal end of the outer sheath is connected to the auxiliary handle.

A high-performance near-pure zinc alloy, a preparation method therefor and a use thereof, relating to the technical field of zinc alloys. The alloy component is that the content of Zn is greater than or equal to 99.5%, and the remaining trace alloy elements include at least two of the following 14 elements: Mg, Mn, Li, Cu, Ag, Ca, Sr, Fe, Zr, Ti, Al, C, Ga, and Si. The alloy has the yield strength ≥ 250 MPa, the tensile strength ≥ 320 MPa, the elongation ≥ 25%, the mechanical property change during one year of room-temperature storage ≤ 5%, the maximum bending force ≥ 2 kN, the stress corrosion sensitivity factor ≤ 15%, the size of corrosion pits after 60 days of immersion ≤ 15 μm, and the standard deviation of the size of corrosion pits ≤ 3 μm. The alloy is suitable for the preparation of biodegradable stents, bone implant devices, medical staplers or anastomotic nails for intestines, blood vessels or nerves, vascular clamps, guided bone or tissue regeneration membranes, heart valve protheses, dura mater repair membranes, soluble bridge plugs and fracturing balls for oil drilling, zinc alloy die castings, electroplated zinc materials, building zinc materials, battery-grade zinc, printing-grade zinc, and zinc-based brazing alloys.

A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108A) of a blood vessel (108), or within or adjacent to a heart valve, includes an energy source (124) and a system controller (126). The energy source (124) generates a plurality of energy pulses. The system controller (126) includes a processor that controls the energy source (124). The system controller (126) is configured to implement an energy control algorithm to control both of (i) a pulse frequency of the plurality of energy pulses, and (ii) an energy level for each of the plurality of energy pulses that are generated by the energy source (124). As the pulse frequency of the plurality of energy pulses increases, the energy level for each of the plurality of energy pulses decreases.

Transcatheter aortic valve prostheses for improving the cardiac function of a patient suffering from coronary artery disease. Transcatheter aortic valve prostheses include a valve component and a frame. The valve component includes valve leaflets and a skirt. The frame includes access cells that improve access to a patient's coronary arteries if further intervention is required and / or includes a window or conduction protection cell that is oriented to align with a portion of conduction system of the heart in situ to reduce conduction disturbances of the anatomy. Suture patterns for attaching a commissure to a commissure post of the frame, and for attaching a tissue bumper to the commissure post, are also described.

The present invention discloses a prosthetic heart valve comprising at least two valve components, a sealant covering the valve components, and an edge-sealing structure. A space is formed between the valve components covered with the sealant. The edge-sealing structure has a closed end face and connects the ends of the sealant to form a closed space within the space. The prosthetic heart valve provided by the present invention can reduce the risk of thrombosis between the valve components. Because the edge-sealing structure is flexible, it has little effect on the compression and gripping of the prosthetic valve, and the addition of the edge-sealing structure does not affect the normal function of the prosthetic valve.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.

A device configured to be positioned within a native heart valve to repair the valve. The device includes a leaflet pinching or capturing mechanism to capture a first leaflet and second leaflet of the native valve and then attach the first leaflet to the second leaflet. The device includes a first surface and a second surface, wherein the first surface and the second surface are movable between an open condition and a closed condition to pinch a first leaflet and a second leaflet of the native valve therebetween. Once the first and second leaflets are captured, portions of the leaflets are fused together, adhered together, or fused and adhered together. In some implementations, a system is configured to access a papillary muscle and ablate tissue of the papillary muscle to disable a conductive pathway to the papillary muscle.

Delivery systems for placing an implantable cardiac device at a native comprising a delivery catheter and an attachment assembly. The delivery catheter can include a proximal portion and a distal portion, and the attachment assembly can be at the distal portion of the delivery catheter. The attachment assembly can include arm pairs in which individual arm pairs include a first arm with connector and a second arm with a retainer. Each first arm extends along a corresponding second arm, and the first arm and / or the second arm in each arm pair moves relative to the other from a locked position to a released position. In the locked position, the retainer interfaces with the connector to maintain engagement between the implantable device and the connector. In the released position, the retainer is positioned relative to the connector such that the implantable device can disengage the connector.

This disclosure relates to a catheter system for introducing a heart valve stent into the body of a patient. The catheter system includes a catheter tip having a seat portion for accommodating the stent in its collapsed state and a stent holder for releasably fixing the stent, wherein the seat portion is constituted by a first sleeve and a second sleeve, said sleeves being moveable relative to each other and relative to the stent holder, and a catheter shaft for connecting the catheter tip to a handle.

Apparatuses, systems, and methods for various devices, such as prosthetic valves. Some examples are directed to improvements in anchoring at a native heart valve, which may reduce possible trauma to a treatment or implantation site. Compliant and flexible anchoring features and methods are disclosed to reduce force upon a treatment or implantation site including heart tissue that surrounds leaflets of a mitral or tricuspid valve. Improved mechanisms for deployment of devices including motorized methods are also disclosed.

Provided herein is a device for simultaneous intraoperative leak testing and visualisation of a heart valve seat, the device comprising an end cap configured to engage with and to sealingly close an opening of a tubular vascular graft, the end cap comprising a backing portion, a connector portion, a view port, and at least one fluid conduit element, the connector portion comprising a distal end dimensioned for placement inside of the opening, a first fastening element comprising an external thread, a second fastening element comprising an internal thread and configured to be rotated onto the first fastening element, and the external and internal threads are adapted such that the first and second fastening elements are fittingly engaged with the tubular vascular graft scalingly secured therebetween by less than one rotation of the second fastening element around the outer circumference.

The transcatheter type artificial polymer heart valve comprises an integrated valve leaflet and a valve frame, the valve frame is of a hollow columnar grid structure, the valve frame is provided with a first end and a second end, the first end is provided with a plurality of stand columns at intervals in the circumferential direction, the integrated valve leaflet comprises a pipe body and a valve leaflet, the pipe body is provided with a third end and a fourth end, and the valve leaflet is arranged in the pipe body. The valve leaflets are arranged in the center of the third end, the valve leaflets are sequentially arranged in the circumferential direction, connecting grooves are formed in the connecting positions of the adjacent valve leaflets, and the connecting grooves are provided with through holes allowing the stand column to penetrate through; a connecting column is arranged on the outer wall of the pipe body, and a connecting hole matched with the connecting column is formed in the petal frame; when the integrated valve leaflet is arranged in the valve frame, the third end and the fourth end correspond to the first end and the second end respectively, the stand columns are inserted into the through holes, and the connecting columns are connected with the connecting holes in a one-to-one correspondence mode. Manual valve sewing is reduced, and the assembly efficiency is improved; stress concentration during opening and closing of the valve leaflet is reduced, and the performance of the valve is optimized.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and / or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and / or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.