1033 results about "Nitric oxide" patented technology

Systems and methods for generating nitric oxide are disclosed. A nitric oxide (NO) generation system includes at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas; and a controller configured to regulate the amount of nitric oxide in the product gas produced by the at least one pair of electrodes by utilizing duty cycle values of plasma pulses selected from a plurality of discrete duty cycles to produce a target rate of NO production based on an average of discrete production rates associated with each of the plurality of discrete duty cycles.

The invention discloses a small waste incineration full-automatic control system and method, and particularly relates to the technical field of solid waste treatment.The method comprises the following steps that waste throwing is recognized through infrared induction, a preheating device is started to heat a combustion chamber, and the heating intensity is adjusted in real time; when the temperature reaches a preset threshold value, the air volume, the feeding time and the combustion time are controlled according to the garbage type, and stable combustion is achieved; the concentration of carbon monoxide, nitric oxide and particulate matter in tail gas is monitored in the whole process, and combustion parameters are automatically adjusted when the emission limit value is close; after combustion is finished, slag is automatically discharged according to the amount of slag; meanwhile, temperature and emission data are collected and uploaded to a remote terminal, and full-process intelligent control and environment-friendly management are achieved; the whole-process automatic control is realized, and the manual dependence is reduced; combustion efficiency and adaptability are improved through an intelligent model; an emission prediction and feedback mechanism is introduced to ensure that the tail gas is environmentally friendly and reaches the standard, and the system stability and the intelligent level are enhanced.

The invention relates to a nitric oxide data analysis method and system for bronchial asthma assessment. According to the method, exhaled air nitric oxide and pulmonary alveolar nitric oxide of a patient, omics data and clinical information are acquired in a standardized manner, and multi-dimensional features are constructed after data cleaning and fusion; comprise an inflammation level index, an inflammation region entropy, an inflammation synergy index, a glucocorticoid response factor, an infection-smoking synergy influence factor and a heredity-symptom distribution index. And outputting initial risk assessment based on an explainable elevator EBM model, and finally generating an asthma risk probability through a weighted integration formula to realize three-level layering: low / medium / high risk. The system dynamically associates treatment decisions, for example, the drug dosage and the monitoring frequency are improved when the risk is upgraded, and the medication scheme is optimized when the risk is degraded. According to the scheme, the limitation of traditional single marker static analysis is broken through, multiple mechanisms of dissection, immunity and pharmacology are fused, the evaluation precision and clinical applicability are remarkably improved, the acute attack rate is reduced, and accurate typing treatment is guided.

The invention belongs to the field of pollutant control, and particularly discloses a method and system for reducing generation of nitric oxide in the ammonia coal combustion process. The method specifically comprises the steps that liquid ammonia is gasified and then subjected to a thermocatalytic reaction to generate hydrogen and nitrogen, and ammonia-doped mixed gas is obtained; and judging whether the ratio of the concentration of hydrogen to the concentration of ammonia in the ammonia-doped mixed gas is greater than or equal to a threshold value or not, if so, discharging the ammonia-doped mixed gas for blending combustion, and if not, carrying out thermal catalytic reaction on the ammonia-doped mixed gas again. According to the method, the ratio of the concentration of hydrogen to the concentration of ammonia in the ammonia-doped mixed gas serves as the judgment standard for whether blending combustion can be conducted or not, the calculation formula of the threshold value is provided by balancing the influence of H2 and NH3 on NOx generation in the combustion process, then flexible regulation and control can be conducted on the raw material side according to the actual blending combustion condition, and the blending combustion efficiency is improved. The method effectively reduces the generation of nitrogen oxides in the ammonia coal combustion process, does not need to regulate and control the combustion side, does not affect the combustion stability and the boiler thermal efficiency, and has the advantages of simple operation and low cost.

The invention discloses photo-thermal controlled-release nitric oxide anti-biofilm hydrogel based on click reaction crosslinking as well as a preparation method and application of the photo-thermal controlled-release nitric oxide anti-biofilm hydrogel based on click reaction crosslinking, the hydrogel is prepared by taking azide group-containing four-arm polyethylene glycol and alkynyl modified hyaluronic acid as matrixes through click chemistry rapid crosslinking under the catalysis of copper-based nanoparticles, the antibacterial biological membrane has remarkable dual anti-biological membrane and anti-inflammatory effects, and can be applied to wound treatment of bacterial biological membrane infection; through a wound surface coating form, under near-infrared light irradiation, copper nanoparticles generate a mild photothermal effect to remove a biological membrane, and Cu < 2 + > is released to promote fibroblast proliferation; nitric oxide can be controllably released, a biological membrane is synergistically eliminated by enhancing lipid peroxidation and destroying a bacterial membrane structure, meanwhile, angiogenesis is promoted, collagen deposition is stimulated, and the wound healing process is accelerated; the invention has the functions of efficient antibiosis and tissue regeneration, and has wide clinical application prospect and development value in the field of infectious wound treatment.

The invention provides a synergistic accelerant suitable for SNCR (selective non-catalytic reduction) denitration and application of the synergistic accelerant. The synergistic accelerant comprises the following components in parts by weight: 2-80 parts of an activating agent, the activating agent is selected from at least one of sodium glycinate, sodium glutamate, sodium iminodiacetate, sodium aspartate, sodium aminopropionate, sodium aspartate and potassium aspartate; 3-12 parts of a catalyst, wherein the catalyst is selected from soluble heteropolyacid; 1-10 parts of a catalytic promoter; the catalytic promoter is selected from at least one of soluble tungstate and molybdate. A trace amount of synergistic accelerant is added into a common SNCR denitration solution, so that the reaction speed of NOx and reducing agents such as ammonia or urea can be increased, a temperature window of SNCR reaction moves downwards, the application range of the traditional SNCR technology is expanded, the removal efficiency of NOx is improved, and a low-cost and high-efficiency method is provided for pollution abatement of nitric oxide in waste gas.

The invention discloses a CFB boiler flue gas denitration automatic control method and system. The control method comprises the following steps: S1, monitoring and controlling a CFB boiler by taking an operator station display as a center; s2, a nitrogen oxide emission value of a boiler tail flue in the CFB boiler is collected in real time to serve as a feedback value; s3, the feedback value is compared with a set target emission value, and the deviation value of nitric oxide at the flue gas outlet and the change rate of the deviation value are calculated; s4, constructing a fuzzy relation between the three PID parameters and the deviation and the change rate of the deviation value, and obtaining a new PID parameter; s5, the stroke of an ammonia water pump is dynamically adjusted according to the new PID parameters, and the amount of the urea solvent sprayed into the boiler is controlled; and S6, the stroke of a dilution water pump and the flow of dilution water are regulated and controlled. By means of early warning, control over spraying of the reducing agent and burdening in the boiler is achieved, it is guaranteed that the denitration system can change along with changes of the boiler operation load, and long-term, reliable and safe operation of boiler denitration is achieved.

The invention discloses a streptococcus suis type 2 gene deletion strain as well as a construction method and application thereof, and belongs to the technical field of biological products. According to the invention, the B9H0105210 gene in the genome of the streptococcus suis serotype 2 SC19 is deleted in a homologous recombination manner for the first time, the hydrogen peroxide and nitric oxide stress resistance of the constructed streptococcus suis serotype 2 gene deleted strain is reduced, and the pathogenicity to mice is obviously weakened; moreover, the growth performance of the streptococcus suis type 2 gene-deleted strain is not greatly different from that of a wild strain SC19, the condition of gene recovery does not exist after continuous passage, and the streptococcus suis type 2 gene-deleted strain has an application prospect as an attenuated live vaccine, has a good immune protection effect on different genotypes of streptococcus suis such as the streptococcus suis type 2 strain SC19 and streptococcus suis type 2 P1 / 7, and has a good application prospect. And a certain cross immune protection performance is achieved.

The present invention relates to: a temperature-sensitive hydrogel for cancer treatment; a photothermal composition comprising the hydrogel as an active ingredient; and a preparation method for the temperature-sensitive hydrogel for cancer treatment. The temperature-sensitive hydrogel of the present invention includes gold nanostars as active ingredients, and thus can generate heat by light irradiation, thereby exhibiting a photothermal therapy effect. In addition, the hydrogel temperature increases so that the release of nitric oxide (NO) from S-nitrosocysteine can be induced. In addition, the temperature-sensitive hydrogel of the present invention includes S-nitrosocysteine as an active ingredient so that, upon a temperature rise due to a photothermal reaction, the penetration of drugs into a tumor site can be improved by the release of NO, and at the same time, apoptosis of cancer cells can be directly caused; and includes an immunotherapy agent as an active ingredient so that tumor size can be effectively suppressed even with the passage of time. Therefore, as a material that enables complex treatment combined with photothermal therapy and immunotherapy, the temperature-sensitive hydrogel of the present invention having the aforementioned effect can be usefully utilized in the field of medicine for cancer treatment.

Disclosed herein are topical nitric oxide (NO) formulations containing a surfactant and methods that deliver NO to treat skin wounds, burns, infections, site of inflammations, or other skin conditions requiring treatment, as well as to eradicate and degrade biofilms on the skin surface. The NO formulations can be modified to prolong the time of NO exposure by modulating the surfactant concentration.

The invention discloses an ammonia-doped coal ignition structure, an ammonia-doped coal burner and an ammonia-doped coal ignition method. The ammonia-doped coal ignition structure comprises an ignition channel, a first-stage fuel channel, a first-stage combustion-supporting channel, a second-stage fuel channel, a second-stage combustion-supporting channel and a main combustion chamber. Fuel in the ignition channel can be ignited through the ignition electrode, primary combustion of ammonia fuel is ignited through ignition flames from the ignition nozzle, then multi-stage ignition combustion of coal doped with ammonia is achieved, ignition is easier, control is easy, the flames are more stable, and meanwhile emission of nitric oxide is greatly reduced. The coal-doped ammonia ignition structure is adopted in the coal-doped ammonia burner, and the coal-doped ammonia ignition method is suitable for the coal-doped ammonia ignition structure and the coal-doped ammonia burner.

The present invention discloses the preparation of an anti-inflammatory peptide derived from the hydrolysis of shell nacre protein and its application in skin repair. The peptide PDFDNGF provided by the invention can effectively promote the proliferation of RAW264.7 macrophage cells and inhibit the excessive production of nitric oxide and cytokines in RAW264.7 cells induced by lipopolysaccharide, while increasing the levels of anti-inflammatory cytokines, demonstrating significant anti-inflammatory activity. Furthermore, the active peptide has a significant proliferative effect on L929 cells, indicating its potential to promote skin wound healing. This invention provides a theoretical basis for the high-value utilization of shell nacre.

The invention discloses a gas compressor gas pipe sealing detection device and detection process, and relates to the technical field of gas pipe detection, the detection device comprises a detection table, a detection box is fixedly arranged on the detection table, a first gas transmission module is arranged on the detection box, and the first gas transmission module is used for inputting oxygen into the detection box; a positioning module used for positioning the air pipe body is further arranged on one side of the detection box, a feeding port is formed in the side, close to the positioning module, of the detection box, and a feeding module is further arranged on the detection table and used for inputting the positioned air pipe body into the detection box; a second gas transmission module is further arranged in the detection box, and the second gas transmission module is used for inputting nitric oxide into the gas pipe body; by means of the detection method, the leakage point can be positioned, and in the detection process, detection liquid cannot be attached to the air pipe body, so that subsequent cleaning and drying treatment is not needed, the detection precision and efficiency are effectively improved, and batch production of the air pipe of the air compressor is facilitated.

The invention relates to the technical field of combustion equipment, and provides a hydrogen fuel nozzle with cavity trapped vortex reinforced mixing and a combustor, the hydrogen fuel nozzle with cavity trapped vortex reinforced mixing comprises a cartridge receiver, a flame tube, a first air inlet pipe and a plurality of micro-mixing spray pipes, and a gas collection cavity is formed in the end, close to an air inlet, of the flame tube; a plurality of mounting channels are formed in the end, close to the air inlet, of the flame tube and penetrate through the mounting cavity, the air collecting cavity and the spraying cavity; each micro-mixing spray pipe is mounted in one mounting channel and comprises a gas inlet end and a gas outlet end, the gas inlet end is communicated with the mounting cavity, the gas outlet end is communicated with the spraying cavity, a groove is formed in the inner wall of each micro-mixing spray pipe, and a vent hole communicated with the gas collecting cavity is formed in the bottom wall of each groove. When air flows in the micro-mixing spray pipe and passes through the groove, vortex is generated in the groove, in this way, mixing of the air and fuel gas is enhanced through the vortex, the mixing uniformity is effectively improved, and therefore emission of nitric oxide is reduced.

Nitric-oxide ionization induced flow tagging and imaging (NiiFTI) is described. In one embodiment a method for characterizing a flow of a gas containing an agent includes ionizing the agent by a source of pulsed light emitting at a frequency overlapping a resonant transition frequency of the agent. In response to ionizing of the agent, a fluorescence of the gas is generated. The method also includes capturing at least one time-delayed image of the flow of the gas, where the capturing is time-delayed with respect to a pulse of the source of pulsed light. The method includes determining at least one property of the flow of the gas by analyzing the at least one time-delayed image of the flow.

The invention relates to a medical device for evaluating physiological parameters of a respiratory system, and the device comprises a sampling device which is used for collecting detected exhaled gas after a rising inflection point of carbon dioxide; the gas sensor comprises a nitric oxide sensor and a carbon dioxide sensor; the processor is used for receiving the gas signal generated by the gas sensor; the processor is configured to establish a linear expression for calculating a risk parameter R according to the detected carbon dioxide concentration and nitric oxide concentration; the linear expression of the risk parameter R is shown in the specification; wherein the parameter is set as a constant; the parameter is nitric oxide concentration; the parameter is carbon dioxide concentration; and the parameter is a nitric oxide dynamic change rate function. Compared with the prior art, the method provided by the invention provides a more comprehensive evaluation capability for airway inflammation and abnormal ventilation.

The invention relates to the technical field of chemical plant smoke filtering, in particular to a chemical plant discharge filtering device with a monitoring function, which comprises a barrel, a gas inlet pipe, a gas outlet pipe and the like, the barrel is communicated with the gas inlet pipe, and the top of the barrel is communicated with the gas outlet pipe. Indexes of pollutants such as sulfur dioxide, nitric oxide, carbon monoxide and carbon dioxide in flue gas can be detected through the flue gas sensor, when the flue gas sensor detects that the pollutants in the flue gas exceed the standard, the controller can control an electric guide rail to work, the electric guide rail drives a first push plate to move forwards, and a first sealing plate can also move forwards; the first sealing plate seals the exhaust pipe, real-time response can be achieved after the filter element is aged and breaks down, the filter element is replaced without shutdown under the condition that it is ensured that smoke does not leak, smoke which is not completely purified is prevented from being exhausted out, and therefore pollution to the environment can be avoided.

The invention discloses preparation of a shell nacre protein hydrolysis anti-inflammatory peptide and application of the shell nacre protein hydrolysis anti-inflammatory peptide in skin repair. The peptide PDFDNGF provided by the invention can effectively promote proliferation of macrophage RAW264.7 cells, can inhibit excessive production of nitric oxide and cytokines in the RAW264.7 cells induced by lipopolysaccharide, can increase the level of anti-inflammatory cytokines, and shows remarkable anti-inflammatory activity. In addition, the bioactive peptide has a remarkable proliferation effect on L929 cells, and it is indicated that the bioactive peptide has the potential of promoting skin wound healing. The method provides a theoretical basis for high-value utilization of the shell nacre layer.

The invention belongs to the technical field of low-nitrogen combustors, and discloses an ammonia-doped hydrogen-doped low-nitrogen coal-fired boiler and a working method thereof.Each corner of a corner tangential boiler body is provided with a plurality of primary air nozzles in the height direction of a main combustion area, the primary air nozzles are provided with stable combustion teeth, and the stable combustion teeth are used for transversely dividing primary air into a thick part and a thin part; a concentrated phase is arranged inside, and a light phase is arranged outside; an ammonia-doped and hydrogen-doped nozzle is arranged above and / or below each primary air nozzle; and each corner of the four-corner tangential boiler body is provided with an over-fire air nozzle in the over-fire air area. By controlling supply of air, fire coal, ammonia and hydrogen fuel, the combustion process is carried out in stages, and generation of nitric oxide is effectively reduced.

The disclosure provides methods for the for treatment of psychosis, such as schizophrenia, or depression (such as bipolar depression) and / or anxiety, comprising administering to a patient in need thereof, (i) a 5-HT2A or 5-HT2A / D2 receptor ligand, for example a substituted heterocycle fused gamma-carboline as described herein, in free, pharmaceutically acceptable salt or prodrug form, and (ii) a nitric oxide donor, separately (sequentially or simultaneously), or in combination (e.g., in a fixed dose combination).

The invention relates to the technical field of chemical synthesis, and discloses a method for preparing short-chain diacid by catalytic oxidation of polyethylene with an ionic liquid, which comprises the following steps: mixing the ionic liquid and polyethylene, and mixing for oxidation reaction in the presence of nitric oxide and oxygen to obtain the short-chain diacid. According to the method, the polyethylene is adopted as the raw material for the first time, the ionic liquid is used as the reaction catalyst and the reaction medium, nitric oxide is catalyzed to generate nitrogen dioxide, efficient catalytic oxidation of the polyethylene is achieved, the short-chain diacid product with the carbon number of 4-12 is obtained, the highest yield reaches 90% or above, and the influence on the yield is not large when the polyethylene recycled material is adopted. The method not only solves the problem of polyethylene waste recovery, but also solves the problem of high preparation cost of short-chain diacid, so that the preparation cost is greatly reduced.

The invention provides a method of delivering, by intermittent inhalation, 200 ppm to 320 ppm gNO for 10 to 45 minutes 2 to 5 times per day to provide a therapeutic amount of gaseous nitric oxide (gNO) wherein the therapeutic amount is a nitric oxide-load (NO load) of 300 ppm-hrs to 900 ppm-hrs of gNO per day over a period of at least 14 days to a patient in need thereof, wherein the patient has a condition associated with a pathogenic microorganism, wherein the intermittent inhalation comprises inhalation of the gNO for a first time period, followed by inhalation of a gas essentially devoid of gNO for a second time period.

The utility model discloses a hollow fiber membrane pyrogenic process lithium resource recovery and pollution treatment system. The method is characterized in that lithium chloride is accurately intercepted and recovered by using a hollow fiber membrane as a recovery stage of a filter material; the pollutants in the flue gas are subjected to catalytic oxidation by a removal stage of a hollow fiber membrane loaded catalyst; the adsorption stage of the hollow fiber membrane loaded adsorbent is used for absorbing difficult-to-oxidize substances; sulfur, nitric oxide and hydrogen chloride are absorbed by a spray tower. The system formed by the four links overcomes the defects of wet recovery, and is efficient, energy-saving and emission-reducing.

The invention relates to the technical field of industrial flue gas purification, in particular to a method for removing NOX in flue gas through cooperation of iron-extracted and depleted molten lead-zinc slag desulfurization tail liquid and an oxidizing agent, and the method comprises the following steps that S1, iron-extracted and depleted molten lead-zinc slag is ground till the particle size is not larger than 0.075 mm, water is added according to the solid-to-liquid ratio of 1: 200 g / mL, and ore pulp is prepared; s2, flue gas containing SO2 is introduced into the ore pulp, and SO2 in the flue gas is removed; s3, raising the temperature of the desulfurization tail liquid from which SO2 is removed to 25-65 DEG C, adding an oxidizing agent, introducing NOX-containing flue gas, and removing NOX in the flue gas; according to the method, the nitric oxide can be effectively removed by utilizing the desulfurization tail liquid of the molten lead-zinc slag after iron extraction and dilution, so that the comprehensive utilization of resources is realized.

The invention relates to the technical field of biomedical materials, in particular to a double-network structure artificial blood vessel with anticoagulation, endothelium promotion and anti-infection functions and a preparation method of the double-network structure artificial blood vessel. The artificial blood vessel comprises a polymer fiber network artificial blood vessel substrate, a microscopic network hydrogel layer penetrating through the polymer fiber network artificial blood vessel substrate, and magnesium-copper alloy particles doped in the hydrogel layer. According to the artificial blood vessel with the double-network structure, the problem that a traditional small-caliber artificial blood vessel is insufficient in mechanical performance is greatly solved, copper ions and magnesium ions are released to the surrounding environment by means of degradation of the magnesium-copper alloy particles in the using process, the microenvironment of the surrounding tissue is adjusted to be alkalescent, nitric oxide is catalytically released, and the mechanical performance of the artificial blood vessel is improved. The artificial blood vessel with the double-network structure is endowed with anticoagulation, endothelium promotion and anti-infection functions. The problems of restenosis and insufficient endothelialization of a small-caliber artificial blood vessel in the prior art are comprehensively solved, and the long-term patency rate of the artificial blood vessel is increased.

The invention discloses a fluorescent probe as well as a preparation method and application thereof. The invention provides a series of fluorescent probes with novel structures, and the fluorescent probes take 2-(isoquinoline-1-yl) pyrrole boron difluoride as fluorophores, so that the fluorescence quantum yield of the probes is improved, the detection resolution of nitric oxide is increased, and the detection sensitivity is improved. The fluorescent probe disclosed by the invention has the characteristics of large Stokes displacement, high fluorescence quantum yield, good selectivity and short response time.

The invention discloses a giant salamander immune regulation meat peptide and application thereof. The meat peptide comprises one or more than two polypeptides selected from SEQ ID NOs: 1-5. The polypeptide can enhance cellular immune response, such as enhancing macrophage proliferation activity, improving macrophage nitric oxide secretion level, enhancing macrophage phagocytic ability, enhancing macrophage antigen presentation ability, enhancing immune organ functions, regulating T cell subpopulation, improving cellular immune factor level and enhancing immune globulin level.

The invention belongs to the technical field of tumor treatment, and relates to a nanometer material for treating tumors based on near-infrared light response in combination with photo-thermal, photodynamic and nitric oxide as well as preparation and application of the nanometer material. The invention relates to a near-infrared light response-based nano material for combined treatment of tumors, which is of a sphere-like structure, takes hollow mesoporous copper sulphide with photo-thermal performance as a carrier, loads a nitric oxide donor, and wraps a phase change material containing a photosensitizer. According to the nano material, photo-thermal conversion of the hollow mesoporous copper sulfide nano particles is triggered through near-infrared light, high temperature is generated, the phase change material is molten, and release of the photosensitizer IR780 and L-Arg is promoted; under irradiation of near-infrared light, IR780 generates active oxygen, and L-Arg is further triggered to release nitric oxide. The linkage mechanism of thermal controllable drug release closely combines photo-thermal, photodynamic and nitric oxide treatment, and the construction of the obtained nano material solves the problem that < 1 > O2 and NO cannot be effectively supplied to tumor sites.

The invention provides application of an immature bitter orange extract in preparation of anti-oxidation and anti-inflammatory drugs. The fructus aurantii immaturus is extracted by using different solvents, and the extract is researched, so that the fructus aurantii immaturus extract has the capability of removing superoxide anion free radicals, ABTS free radicals and DPPH free radicals; in addition, the immature bitter orange extract can also reduce the content of nitric oxide, tumor necrosis factor-alpha, interleukin-1beta and interleukin-6 released by LPS-induced macrophages. The fructus aurantii immaturus extract has anti-oxidation and anti-inflammatory effects, and is used as an anti-oxidation and anti-inflammatory drug to develop a new application of an old drug of the fructus aurantii immaturus extract.

The invention discloses a low-nitrogen oxide burner structure which comprises an air inlet barrel, an air barrel, a fire gathering cover, a flame stabilizing barrel, a gas main pipe and a gas ejector with an ejection pipe. The air inlet barrel, the air barrel, the fire gathering cover and the flame stabilizing barrel are sequentially in butt joint and communicated to be used for conveying air, the gas main pipe is arranged in the air barrel, and the gas main pipe is branched into a plurality of gas branch pipes. A center air pipe is arranged in the center of the flame stabilizing barrel, a plurality of blades are arranged in the flame stabilizing barrel around the center air pipe, and gaps between the adjacent blades form outer air through grooves. The gas branch pipes extend into inlets of the injection pipes in a one-to-one correspondence mode with gaps, and the injection pipes are arranged around the flame stabilizing barrel by a circle. A two-stage air conveying channel is formed by the central air pipe and the outer air through groove, and a fuel gas input channel is formed by the injection pipe. The mixing uniformity of air and fuel gas is enhanced, graded conveying of the fuel gas and the air is achieved, combustion flames are stable, flue gas can flow back for combustion, and meanwhile generation of nitric oxide is reduced.