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4041 results about "Biofilm" patented technology

A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. These adherent cells become embedded within a slimy extracellular matrix that is composed of extracellular polymeric substances (EPS). The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides, proteins, lipids and DNA. Because they have three-dimensional structure and represent a community lifestyle for microorganisms, they have been metaphorically described as "cities for microbes".

Methods for promoting plant health

ActiveUS20100260735A1Promoting health of plantImprove pathogen resistanceBiocideKetone active ingredientsGrowth plantBiofilm
A method for promoting the health of a plant comprises administering malic acid to the plant or the soil in an amount effective to recruit plant growth promoting rhizobacteria (PGPR) to the plant. Administration of malic acid promotes biofilm formation of PGPR on the plant's roots, thereby restricting entry of a foliar pathogen through stomatal pores present in the leaves. Another method for promoting the health of a plant comprises administering acetoin to the plant or the soil in an amount effective to increase pathogen resistance in aerial parts of the plant.
Owner:UNIVERSITY OF DELAWARE

Composition and methods for preventing and removing biofilm embedded microorganisms from the surface of medical devices

A biofilm penetrating composition for coating medical devices for substantially preventing the growth or proliferation of biofilm embedded microorganisms on at least one surface of the medical device is disclosed. A biofilm penetrating composition solution for cleaning medical devices which is capable of substantially removing all of the biofilm embedded microorganisms from at least one surface of medical devices is also disclosed. The biofilm penetrating composition coating and solution include a biofilm penetrating agent and may also include a base material. Medical devices coated with the biofilm penetrating composition and methods for coating medical devices and methods for removing biofilm embedded microorganisms from at least one surface of the medical devices are also disclosed.
Owner:BAYLOR COLLEGE OF MEDICINE

Diagnostic Oral Health Care Implement and System

A diagnostic oral health care implement and system are provided for use during oral health care activities. The diagnostic oral health care implement has a diagnostic sensor. The diagnostic sensor provides diagnostic measurements in a plurality of formats including the biofilm thickness of dental plaque. The diagnostic oral health care system has a diagnostic oral health care implement and a first data transfer medium. The system optionally has any combination of a second data transfer medium, a network storage device, and a third data transfer medium. The system provides for the collection of diagnostic measurements and transmission of the data into a readable, usable form for the user via an oral health care implement.
Owner:BEAM TECH

Oral hygiene devices employing an acoustic waveguide

InactiveUS20070011836A1Great tasteStimulates and massages gumBrushesWindow cleanersUltrasonic sensorAcoustic energy
An oral hygiene device having an ultrasound transducer 22 and an acoustic waveguide 24 facilitating the transmission of ultrasonic acoustic energy to fluids in the oral cavity is disclosed. Preferred ultrasound operating parameters for operation in aqueous environments and in dental slurries are disclosed. Devices may incorporate a drive motor 16 for oscillating a device head 23, acoustic waveguide 24 and one or more bristle tuft(s) 26 at sonic frequencies, and preferred sonic operating parameters are also provided. Multi-element piezoelectric transducer assemblies 30, 40, and various control and communications features are disclosed. Oral hygiene devices disclosed herein achieve improved plaque and stain removal from the teeth as well as interproximal and subgingival regions, while enhancing the user experience, massaging the gums, stimulating dental tissue, and disrupting biofilm.
Owner:ULTREO

Compositions for treating biofilm

A composition for treating a biofilm comprises a first anchor enzyme component to degrade biofilm structures and a second anchor enzyme component having the capability to act directly upon the bacteria for a bactericidal effect.
Owner:BUDNY JOHN A +1

Solvating system and sealant for medical use in the middle or inner ear

ActiveUS20070264310A1Increased drug resistanceReduction and elimination in amountGogglesPharmaceutical delivery mechanismBiofilmEffusion
Chronic Otitis Media with Effusion (COME), Recurrent Acute Otitis Media (RAOM), cholesteatoma, and other bacterial ear conditions may be treated by applying a solvating system containing greater than 0.2 wt. % surfactant to a bacterial biofilm in the middle or inner ear, disrupting the biofilm, and applying a protective layer of a polymeric film-forming medical sealant.
Owner:MEDTRONIC XOMED INC

Antimicrobial coating for inhibition of bacterial adhesion and biofilm formation

InactiveUS20080063693A1Increased coating antimicrobial efficacyPrevent bacterial adhesionBiocideAntifouling/underwater paintsWater insolubleMetallic materials
The present invention provides antimicrobial coatings for coating substrate surfaces, particularly medical devices, for preventing bacterial adhesion and biofilm formation by inhibiting microbial growth and proliferation on the coating surface. The antimicrobial coatings are composed of a hydrogel and a bioactive agent including a substantially water-insoluble antimicrobial metallic material that is solubilized within the coating. Antimicrobial coating formulations for obtaining such coatings, and coating methods are also described.
Owner:BACTERIN

Membrane supported bioreactor for conversion of syngas components to liquid products

Ethanol and other liquid products are produced by contacting syngas components such as CO or a mixture of CO2 and H2 with a surface of a membrane and transferring these components in contact with a biofilm on the opposite side of the membrane. These steps provide a stable system for producing liquid products such as ethanol, butanol and other chemicals. The gas fed on the membrane's gas contact side transports through the membrane to form a biofilm of anaerobic microorganisms that converted the syngas to desired liquid products. The system can sustain production with a variety of microorganisms and membrane configurations.
Owner:COSKATA INC

Microfluidic chemostat

A chemostat that includes a growth chamber having a plurality of compartments, where each of the compartments may be fluidly isolated from the rest of the growth chamber by one or more actuatable valves. The chemostat may also include a nutrient supply-line to supply growth medium to the growth chamber, and an output port to remove fluids from the growth chamber. Also, a method of preventing biofilm formation in a growth chamber of a chemostat. The method may include the steps of adding a lysis agent to a isolated portion of the growth chamber, and reuniting the isolated portion with the rest of the growth chamber.
Owner:CALIFORNIA INST OF TECH

Biofilm formation to define risk for colon cancer

Methods of identifying subjects at increased risk of cancer, based upon detection of biofilms and / or biofilm-associated microbes within a subject, are disclosed. Therapies designed to prevent formation and / or reduce the size of biofilms in a subject identified to be at increased risk of cancer based upon detection of biofilms and / or biofilm-associated microbes are disclosed. In particular embodiments, the invention provides for identification of a subject at elevated risk of developing or having colorectal cancer and / or a colorectal adenoma, based upon detection of a biofilm and / or biofilm-associated bacteria within the gastrointestinal tract of the subject (optionally, within a biopsy specimen and / or stool sample of such subject). Therapies involving administration of an antibiotic agent and / or a probiotic agent to a subject, to prevent or reduce biofilm formation within the gastrointestinal tract of the subject, optionally provided in combination with additional cancer therapy, are also disclosed.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Combined activated sludge-biofilm sequencing batch reactor and process

InactiveUS20040206699A1Similar oxygen transfer efficiencyRemoval can be promoted and increasedTreatment using aerobic processesSeparation devicesSequencing batch reactorActivated sludge
A new biofilm-activated sludge Sequencing Batch Reactor (SBR) treatment process for sewage or wastewater has successfully been developed as the third generation SBR (SBR3). This new SBR3 process utilizes a multi-stage and multi-sludge SBR configuration receiving either continuous or intermittent inflow of wastewater. Each stage has individually controlled continuous or alternating anaerobic / anoxic / aerobic operation, with or without mixing and recycling from the other stage(s). The configuration and operation is dependent upon the treatment objectives and effluent discharge requirements. In the preferred embodiment, carriers are used to facilitate control of operating conditions.
Owner:KINGSFORD ENVIRONMENTAL H K

Method of and equipment for washing, disinfecting and/or sterilizing health care devices

InactiveUS20040037737A1Inexpensive, but effectiveLavatory sanitoryDeodrantsPathogenic microorganismBiological membrane
The invention provides a method for automatically washing, disinfecting and / or sterilizing health care equipment and / or cooking and catering utensils. The method includes the steps of placing the equipment to be washed in an enclosure; introducing a first electrochemically activated aqueous solution into the enclosure; and either sequentially or simultaneously introducing a second electrochemically activated aqueous solution into the enclosure. The first solution is characterised therein that it has dispersing or surfactant characteristics for at least partially dispersing a biofilm, pathogenic microorganisms, contamination or the like. The second solution is characterised therein that it has biocidal characteristics for killing microorganisms and disinfecting and / or sterilizing the equipment. The invention also extends to an apparatus for use in the above method.
Owner:RADICAL WATERS IP

Organism growth suppression using ultraviolet radiation

ActiveUS20070205382A1Suppress and prevent growthGrowth inhibitionRadiation pyrometryFire rescueBiological bodyBiofilm
A solution for suppressing organism growth using ultraviolet radiation generated by solid state ultraviolet radiation emitters, such as ultraviolet diodes is provided. The invention includes a connection structure that includes a plurality of solid state ultraviolet radiation emitters disposed thereon. Each of the plurality of solid state ultraviolet radiation emitters emits ultraviolet radiation having a wavelength less than or equal to four hundred nanometers to harm a target organism that may be present on a surface. In one embodiment, the connection structure comprises a two-dimensional mesh that may be placed adjacent an air filter, incorporated in a cover, and / or moved with respect to a surface, such as the interior of an air duct. In this manner, the invention can suppress and / or prevent the growth of organisms, such as biofilms and mold, in locations that are susceptible to such growth.
Owner:SENSOR ELECTRONICS TECH

Preventing biofilm formation on implantable medical devices

ActiveUS20100168808A1Reduces and prevents implantReduces and prevents and surgery-related complicationMammary implantsDiagnosticsBiofilmMedical device
Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and / or holding the cardiac rhythm management device or other implantable medical device and preventing or retarding the formation of a biofilm.
Owner:MEDTRONIC INC

Nutrition slow-release type biofiller for water treatment and its preparation method

This invention discloses a nourishing slow-released type organic bulking agent for processing water and its preparation. This bulking agent includes 60-100 parts of high polymer basis material, 1-15 parts of nutrient substance, 1-10 parts of slow-releasing control substance, and 1-10 parts of dispersing lubricant. When prepare, lubricate slow-releasing control substance with 0.5-3 parts of dispersing lubricant; lubricate high polymer basis material with remaining dispersing lubricant, add in stirring machine, mix with above mixture, mix uniformly, transfer mixture into stirring dipper of plastic injection molding machine, extrude and form by bulking agent tooting. Organic bulking agent prepared by this invention slow-releases nutrient substance that is required for microbes forming biofilm. It has characteristics of fast forming biofilm, more microbial biomass, and activity. It is especially suitable for oxygen degrading process of waste water that contains difficult degraded toxic pollutant.
Owner:SOUTH CHINA UNIV OF TECH

Oral hygiene products containing ascorbic acid and method of using the same

The present invention is directed to dental compositions, including dentifrices, containing ascorbic acid for removing and inhibiting dental biofilms which form plaque and tartar, and also for treating and preventing gingivitis and periodontitis. The ascorbic acid composition can contain may additional ingredients, including an enamel-strengthening component, and be used in many different forms, including breath spray, chewing gum, dental floss, dental powder, gargle, lozenge, mouth spray, mouth wash, tooth gel, tooth liquid, tooth paste and tooth strips. Also described in a method of using a dental composition containing ascorbic acid in order to treat plaque and tartar as well as gum disorders.
Owner:DENTECH

Microbial Growth Assay

InactiveUS20080166753A1Rapid and inexpensive and easy to useBioreactor/fermenter combinationsBiological substance pretreatmentsBiofilmMicroorganism
Susceptibility of sessile microorganisms to antimicrobial agents is tested with a method comprising growing the microorganisms on a support to form a biofilm, contacting the biofilm with a metabolic substrate having a chromogenic and / or fluorogenic moiety to continue a base-line metabolic activity of the biofilm, contacting the biofilm with one or more antimicrobial agents, determining an experimental metabolic activity of the biofilm by measuring a signal from the metabolic substrate, and comparing the base-line metabolic activity with the experimental activity. The biofilm may be grown in a device comprising a plurality of wells, each well having a planar bottom and at least on wall, a plurality of supports comprising discs for growing the biofilm, each support disposed within a well perpendicular to the planar bottom, and at least one cover that fittably seals the top of each well.
Owner:UTI LLP

Oral Compositions Comprising Propolis

InactiveUS20070140990A1Reduced immune system responseEnhance systemic healthCosmetic preparationsAnthropod material medical ingredientsBiofilmPropolis
Oral compositions are provided that comprise a propolis extract; an oral care active compound chosen from: a cationic antibacterial agent, an anti-attachment agent, a biofilm disruption agent, and an anti-inflammatory agent; and a source of fluoride ions. Further, in certain embodiments, the oral composition comprises an anionic polymeric linear polycarboxylate. The oral composition can be in a form of a mouth rinse, a dentifrice, a confectionary, a medicament, or a film. Methods of making and using the oral compositions are also provided.
Owner:COLGATE PALMOLIVE CO

Tidal vertical flow wastewater treatment system and method

A wastewater treatment system includes a tidal, sequential vertical flow marsh cell system having at least three marsh cells in serial forward fluid communication. Incoming wastewater to be treated is channeled to at least the first and a second marsh cell, and a portion of water exiting a final marsh cell, to the first marsh cell surface. Each marsh cell is alternately flooded and drained for enhancing aeration of incoming water and marsh cell contents, which include media and plant roots having biofilms growing thereon, the biofilms including a population of nitrifying and denitrifying bacteria, for achieving substantially simultaneous nitrification and denitrification of the wastewater.
Owner:DHARMA IP +1

Implants with attached silylated therapeutic agents

The present invention is directed to implants that include therapeutic molecules bonded to their surfaces. The therapeutic molecules interact with cells that are adjacent, near, or adhering to the implant. The covalently-bonded therapeutic molecules may be released from the implant surface by changes in pH or enzymes characteristic of cells adjacent to the implant. Preferably the covalently-bonded agents include an antibiotics that are released from the implant surface by bacteria and in this way ensures that the antibiotic is released at sites on the implant that would serve as centers for both bacterial colonization and biofilm formation.
Owner:SMART TECH INC (CA)

Membrane supported bioreactor for municipal and industrial wastewater treatment

A membrane supported biofilm reactor uses modules having fine, dense, non-porous hollow fibers made from Polymethyl pentene (PMP) formed into a fabric with the PMP as the weft. One or more sheets of the fabric are potted into a module to enable oxygen containing gas to be supplied to the lumens of the hollow fibers. Various reactors using such modules are described.
Owner:ZENON TECH PARTNERSHIP

Supported biofilm apparatus and process

A membrane supported biofilm reactor uses modules having fine, hollow fibres, for example, made from melt spun thermoplastic polymers treated after spinning to increase their permeability to oxygen, used, for example, in tows or formed into a fabric. In one module, one or more sheets of the fabric are potted into a module to enable oxygen containing gas to be supplied to the lumens of the hollow fibres. Various reactors and processes, for example to treat wastewater, using such modules are described. In one process, oxygen travels through fibers, optionally through an attached biofilm, to oxygenate surrounding water. Mechanical, chemical and biological methods, for example endogenous respiration, are used to control the thickness of the biofilm.
Owner:ZENON TECH PARTNERSHIP

Biocidal compositions and methods of using the same

An antimicrobial composition with synergistic biocidal activity is described which comprises at least one antimicrobial polymeric biguanide and at least one antimicrobial vicinal diol, said vicinal diol comprises at least one monoalkyl glycol, monoalkyl glycerol, or monoacyl glycerol, to diminish or eliminate biofilm communities. Such synergistic interaction is effective in wound treatment, particularly for chronic wounds, burns and battlefield-induced wounds, as well as for disinfecting non-biological surfaces. The antimicrobial composition can also be prepared as viscous solutions or as gels. The antimicrobial composition may be added to a substrate and dried, such as to a catheter, or to a foam, or to a fiber wound dressing, or coated as a viscous solution or gel upon such devices, to provide controlled release antimicrobial activity.
Owner:ROCHAL TECH LLC
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