5781results about "Pharmaceutical containers" patented technology

A drug supply apparatus that packages a drug with packaging paper that is conveyed from an upstream side to a downstream side, the packaging paper being folded in half with an opening on an upper side, the drug supply apparatus including: a nozzle that dispenses the drug into the packaging paper, the packaging paper including a sealed part, in which the nozzle includes: an insertion guidance piece that protrudes downward and positions a folded part of a lower end of the packaging paper in a state of being inserted in the packaging paper from the opening on the upper side, and a posture adjustment part that guides to inside of the packaging paper the drug, and causes the drug to stand while shifting the drug toward the sealed part side in the packaging paper, the posture adjustment part being provided on the downstream side of the insertion guidance piece.

A zwitterionic polymer coating with surface grafting crosslinking, its preparation method and application are disclosed, which relate to surface modification of biomedical materials, pipelines and other medical equipment, such as extracorporeal blood circulation devices, artificial blood vessels, catheters, endoscopes and other medical equipment, to provide functions such as anticoagulation and anti-biological adhesion. The disclosure constructs the zwitterionic polymer coating with simple process and excellent performance by simulating the structure of the blood vessel intima, having the surface micro-nano structure similar to the blood vessel intima, extremely low friction coefficient, soft elasticity and super hydrophilicity, realizing zero activation and zero adhesion of blood platelets, further providing the blood circulation effect of “blood undisturbed”, which is beneficial to avoiding the problems of thrombus of artificial blood vessels in vivo, various complications caused by clinical blood extracorporeal circulation and the like, and has great clinical application value.

The invention provides a medicine dispensing machine which comprises a frame, and a medicine bottle box for storing ampoule bottles and penicillin bottles, a liquid bag box for storing liquid bags and a suction and injection device hanging frame for conveying suction and injection devices are arranged in the frame. An ampoule bottle opening device for opening an ampoule bottle, a penicillin bottle cover opening device for opening a bottle cover of the penicillin bottle, a penicillin bottle liquid medicine mixing device for mixing and uniformly shaking liquid medicine injected into the ampoule bottle, and a marking device for marking a liquid bag injected with the mixed liquid medicine are arranged in the frame; the frame is internally provided with a sucking and injecting manipulator which is used for clamping a sucking and injecting device and sucking and injecting liquid medicine of an ampoule bottle into a penicillin bottle, all the devices are transferred through a transferring manipulator, full-automatic medicine dispensing is carried out, and the medicine dispensing efficiency is improved.

A support device for supporting a plurality of containers for pharmaceutical use to be handled in a processing line includes a plate having a plurality of first housing seats, wherein each first housing seat includes a first end edge defining an opening; and a base within each first housing seat, wherein the base includes at least one stacking element protruding above the first end edges of the first housing seats.

A tamper evident seal structure for a vial septum or other cover having a housing including a sidewall terminating in oppositely disposed open and closed ends. A retainer is fixedly disposed within the housing and structured for retaining engagement with a portion of a vial, substantially adjacent the vial cover. The housing also includes a pressure member disposed within an interior thereof in attached, relation to the closed-end. The pressure member and the retainer are cooperatively disposed and structured to respectively exert pressure on the vial cover concurrent to retaining engagement with the vial. Tamper evident capabilities are at least partially defined by a detachment of a removable sidewall section from a remainder of said sidewall.

A holding device configured to support medical containers includes a supporting plate having a first surface, a second surface, a peripheral edge between the first surface and the second surface, and a plurality of openings through the supporting plate configured to receive the medical containers. The surfaces of the supporting plate include a peripheral lower portion extending inward from the peripheral edge; at least one upper portion enclosed by the peripheral lower portion; and at least one upwardly angled portion extending between the lower portion and the upper portion. The holding device further includes a plurality of chimneys protruding from the first surface and / or the second surface of the supporting plate at least partially enclosing the plurality of openings, such that the plurality of chimneys guide insertion of the medical containers into the plurality of openings.

A childproof pill container has a top lid, an upper lid, a box body, a bottom lid, and a childproof lock. The upper lid is movably mounted below the top lid and has a first through hole. The box body is mounted below the upper lid and has a second through hole. The bottom lid is mounted below the box body and has a third through hole. The childproof lock includes a rotatable member and an accessory. The rotatable member is mounted through the first through hole, the second through hole and the third through hole and contact the top lid. The rotatable member comprises a first block. The accessory comprises a first opening corresponding to the first block. When the first block is aligned with the first opening, the rotatable member can move upwardly to push the top lid, so the childproof pill container can be opened.

A pill container has a body, at least one lid, and at least one elastic assembly. The body comprises a first wall, a second wall, and at least one compartment. The first wall and second wall are two opposite sides of the body. The compartment is located between the first wall and the second wall. The lid is pivotably mounted on the second wall of the body. The elastic assembly is located on the second wall, and has a flexural segment and a first protruding section. The first protruding section is located on the flexural segment and contacts the second wall. The first protruding section supports a space between the flexural segment of the elastic assembly and the body.

Systems and methods for the transfer of medical fluid are provided. A medical fluid transfer system may comprise a pump configured to transfer fluid through a tube assembly having a first connector configured to couple to a source container and a second connector configured to couple to a target container. The medical fluid transfer system may also comprise a destination sensor configured to output information about the target container. The medical fluid transfer system may further comprise a control system configured to operate the pump based on an operational setting associated with fluid volume; receive measurement data representing a measurement of the target container by the destination sensor, and adjust the operational setting based on an observed volume of fluid transferred to the target container.

A quick-fill pill organizer has a box, multiple retrieving covers, and a packaging cover. The box has multiple compartments. Each compartment has a retrieving opening and a packaging opening. The retrieving cover is mounted on the retrieving opening and corresponds to the compartment one-to-one such that the corresponding compartment connects to or is blocked from the outside. The packaging cover is mounted on the packaging openings such that all the compartments connect to or are blocked from the outside at the same time. When the retrieving openings are upward, the retrieving cover of the specific compartment can be opened. When the packaging openings are upward, the packaging cover can be opened or closed such that all of the compartments connect to or are blocked from outside at once.

A vial adaptor can include a connector interface and / or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and / or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly.

The invention provides an anticoagulant coating for medical instruments, which can be used in the field of regenerative medical instruments. The prepared anticoagulant coating has short-term and long-term anticoagulant performance, and in addition, the thrombin responsive nanoparticles wrapped in the hydrogel coating can selectively release a factor Xa (FXa) inhibitor apixaban according to needs, so that thrombosis is inhibited in the middle stage of implantation. In-vitro and in-vivo experimental evidences show that after the material is implanted for a long time, an organized endodermis can be seen on the surface of the material, and the material has a special antithrombotic characteristic. The dynamic adjusting system has a multi-layer protection mechanism, and a new thought can be provided for designing the surface of a contact blood material adapting to environmental conditions.

The invention belongs to the field of biological medicine, and particularly relates to application of recombinant III-type humanized collagen in an injection. The invention provides an injection, the injection comprises recombinant III-type humanized collagen, the amino acid sequence of the recombinant III-type humanized collagen comprises n repetitions of the sequence as shown in SEQ ID NO.1, n is an integer greater than or equal to 1, and when n is an integer greater than or equal to 2, the repetitions are directly connected; moreover, when the injection is applied in one application period, the total application amount of the recombinant III-type humanized collagen is less than or equal to 3640 mg / kg. The recombinant III-type humanized collagen has high-dose injection safety, and can be applied in a single high-dose manner or continuously applied to realize high-dose application in a total amount level.

The invention relates to the technical field of coating surface preparation, in particular to an anticoagulant coating based on novel tick-derived anticoagulant protein Qinghaenin and a preparation method of the anticoagulant coating. The functional layer of the anticoagulant coating comprises the following components: anticoagulant protein Qinghaenin or a functional peptide fragment Qinghaenin 167-192 of the anticoagulant protein Qinghaenin, wherein the amino acid sequence of the functional peptide fragment is as shown in SEQ ID NO. 2. The preparation method of the anticoagulant coating comprises the following steps: by using a polydopamine coating as a substrate layer, covalently grafting through an amido bond, immobilizing anticoagulant protein Qinghaenin capable of inhibiting FXII factor activation or a functional peptide fragment Qinghaenin 167-192 thereof on the surface of a medical polymer material, and successfully constructing a novel anticoagulant coating. Compared with an unmodified medical polymer material, the modified coating can significantly enhance the hydrophilic performance of the material and inhibit platelet adhesion and activation, finally effectively prolongs the in-vitro blood coagulation time, and shows excellent anticoagulation performance.

The invention discloses a portable field multifunctional medical instrument, and relates to the technical field of medical instruments, the portable field multifunctional medical instrument comprises a shell with a Y-shaped cross section, a main frosted knife abutting against an ampoule bottle opening is arranged at the middle position of the shell, and a curved plate located above the main frosted knife is arranged at the middle position of the shell; a driving assembly used for driving the curved plate to move to impact the tip end of an ampoule bottle to achieve shell ejection is arranged in the shell, a bottle opening groove used for opening an aluminum cap bottle is formed in the lower surface of the shell, and the bottle opening groove is composed of a plurality of sections of curved surfaces of different sizes. The device integrates the multiple functions of bottle opening, marking, horizontal positioning, guiding and the like, medical staff can achieve various operations by taking the device without repeatedly finding and taking various medicine related tools in a first-aid kit, the time of the medical staff is saved to a certain degree, and the life rescue efficiency is improved.

The present disclosure provides an electronic medicine box with a medicine cup and its usage method. The electronic medicine box with a medicine cup includes a housing, a cellular tray, a connecting assembly, a plurality of medicine cups, a driving mechanism, and a lifting mechanism. The housing is provided with a medicine taking port. The cellular tray is provided with a plurality of placement slots that are configured for accommodating the plurality of medicine cups. The cellular tray is rotatably disposed inside the housing through the connecting assembly, and is provided with the driving mechanism that is configured for rotating the cellular tray. The lifting mechanism is configured for pushing the medicine cup out of the placement groove towards the medicine port. The electronic medicine box with the medicine cup further includes a first infrared sensor, a camera, and a first sensing element.

The present disclosure relates to a container assembly including a multi-chamber container that fits within a protective outer sleeve. The container includes covers for allowing the chambers to be individually accessed. The container includes an integrated retention arrangement that allows the container to be secured within the outer sleeve in a manner in which unintended longitudinal movement between the outer sleeve and the container is prevented.

A multistage treatment system for a liquid, the system including a first stage with a first boiling vessel and a first heater configured to boil the liquid in the first boiling vessel at a first pressure. The boiling of the liquid generates vapour including volatile contaminants. A first vapour outlet is configured to vent the vapour from the first boiling vessel. A liquid outlet provides for fluid flow from the first boiling vessel to a subsequent stage. A second stage comprises a second boiling vessel configured to receive liquid from the liquid outlet and a second heater to boil liquid in the second boiling vessel to generate vapour. A condenser receives the vapour from the second boiling vessel and condenses the vapour to a liquid that is treated. An outlet is configured to dispense treated liquid.

A container for organized storage and selective accessibility of items, such as medications. The container includes a base with a base plate and a central base hub, supporting the plurality of pill cases, each with a truncated sector shape and partitioned into two compartments accessible from opposing ends. The container incorporates a magnetic coupling system, comprising a plurality of primary magnetic elements on the base hub and a plurality of secondary magnetic elements on the pill cases, thereby enabling each pill case to attach to the base in one of two orientations, providing access to either compartment.

A vial adapter comprises an adapter body comprising a top wall and a sidewall projecting from the top wall in a longitudinal direction to form a receptacle with a distal side of the top wall. The receptacle is configured to receive at least a portion of a barrel head of an injection vial. A movable part comprises a base part and a spike fixed to the base part. The spike extends through the top wall in a distal direction into the receptacle. An actuating member is mechanically coupled to the movable part, and is movable relative to the adapter body from a start position to an end position along a first direction to induce a distally directed displacement of the movable part relative to the adapter body. The mechanical coupling between the movable part and the actuating member is releasable when the actuating member is in the end position.

A dispensing device for dispensing a beneficial agent configured to transition between an inactive state and an active state. The dispensing device can include a body, a pressure chamber, a primary container, and / or a diaphragm. The pressure chamber and diaphragm may both be disposed within the body, and the primary container may be disposed within the pressure chamber and engaged with the diaphragm. The primary container may include a distal end with a septum or pierceable fitment disposed on a distal side of the diaphragm. The dispensing device may be configured to transition between an inactive state and an active state when a pressurized fluid is provided to the pressure chamber by moving the primary container distally against the diaphragm to cause the diaphragm to deform, including stretching a section of the diaphragm in a distal direction.

A vessel including a thermoplastic wall enclosing a lumen is disclosed. The wall supports an SiOx composite barrier coating or layer, for which x is from 1.8 to 2.4, between the wall and the lumen. High Resolution X-ray Photoelectron Spectroscopy (XPS) shows the presence of an interface between the composite barrier coating or layer and the wall or substrate. In one aspect, the interface has at least 1 mol. % O3—Si—C covalent bonding, as a proportion of the O3—Si—C covalent bonding plus SiO4 bonding. In another aspect, the interface has an Si 2p chemical shift to lower binding energy (eV), compared to the binding energy of SiO4 bonding. The result is a tightly adherent composite barrier coating or layer having a high degree of adhesion to the substrate under practical use conditions. Methods of applying the composite barrier coating or layer are also disclosed.

A container system with a recordable device having a substantially unaltered packaging profile when compared to standard commercially available prescription containers. The container includes a bottle having a cylindrical body having a length greater than its width. A cap is provided with an inclined spiral or helical land and stops to permit it to be affixed to the container. The cap is equipped with a snap fit ring or a fitting on its underside. A recording device is configured with a land or snap ring removably engageable with the snap fit ring on the underside of the cap. The cap has an aperture to accommodate a recording switch on the recording device. The cap is provided with a speaker switch aperture to permit the user to activate the message on the recording device to hear about the contents of the bottle.

Disclosed herein are modular container systems having child-resistant containers, tray inserts and tray frames. Also disclosed are methods using the modular container systems and methods of storing substances in containers. The containers have a container base and a container cap and provide for child-resistant containers. A user can releasably remove the container cap from container base with a squeeze and lift sequence. For example, the user squeezes opposite sides of the container base, which releases a locking mechanism and allows for removal of the cap by lifting or pulling the container cap off from the container base. The components of the modular container system are modular and stackable. The modular system allow for organized, efficient, accessible and storage of the child-resistant containers. The modular container system also allows for easy counting, sorting and processing of the containers.

A medicine refrigeration cup with a portable medicine box is provided, which includes a cup body, a refrigeration device, a hanging ring, and a medicine box. The cup body includes a cup main body and a cup cover, the refrigeration device is provided in the cup cover, the hanging ring includes a ring-shaped member sleeved on the cup main body and a first hanging groove protruding from one side of the ring-shaped member. The first hanging groove includes a first outer groove wall. The medicine box includes a second medicine compartment, and an end portion provided at one axial end of the second medicine compartment. The end portion includes a second hanging groove. The second hanging groove includes an open end, a closed end, and a second outer groove wall. The second outer groove wall is inserted into the first hanging groove.

A closure system for a medication container, the interior of which is accessible via a container opening designed in the manner of a bottle mouth, comprising a bump cap with an annular lid having a central opening, on the outer circumference of which is arranged a number of latching elements which can be brought into engagement with an outer bead mounted circumferentially on the container opening, and a one-piece closure plug with a closure body which completely fills the central opening of the annular lid and can be brought into latching engagement therewith, is intended to enable continuous compliance with even high sterility requirements during handling in a simple and reliable manner. For this purpose, the closure body is designed as a duckbill valve.