21 results about "Connective tissue" patented technology

The invention relates to the technical field of intelligent medical treatment, and discloses a connective tissue disease related lung disease early screening method and system based on deep learning, and the method comprises the steps: obtaining clinical data, a high-resolution chest CT image and biomarker data of a to-be-screened target; the clinical data, the high-resolution chest CT image and the biomarker data are input into a deep learning feature extraction and fusion module, high-dimensional clinical features, image feature vectors and biomarker time sequence feature vectors are extracted and fused, and fused feature vectors are obtained; and inputting the fusion feature vector into an early screening and typing module, and outputting a lung abnormal risk detection result. According to the application, the effects of early diagnosis of connective tissue disease related lung diseases and timely intervention can be achieved.

A wireless augmented reality (AR) system for use by medical practitioners during diagnostic, surgical, or interventional procedures is disclosed. The system includes AR eyewear with integrated heads-up displays (HUDs) embedded in semi-transparent optical lenses, enabling video content to be projected without obstructing the user's natural field of view. Each lens includes a high-resolution micro display and an ambient light sensor for automatic brightness adjustment. The eyewear is coupled via a wired connection to a portable control unit containing a microprocessor for real-time decoding and formatting video signals. A wireless transmitter connects to a medical video source and transmits the live feed to the control unit via a high-bandwidth wireless protocol. The system enables projection of anatomical overlays in real-time, supporting visualization of muscle tissue, nerves, tendons, connective structures, and any other human or animal body part.

The present invention provides a method and composition for treating a disease, wherein the disease is a condition and / or disease of diffuse connective tissue disease. The invention also provides an MHC deficient modified immune cell and a polynucleotide targeting the cell.

An optimized dental implant system comprising: - at least one dental implant; - at least one customized post; - at least one healing cap made of PMMA or PEEK having a locking taper and a flared lower portion, configured to be fully inserted into and interlocked with the post; and - at least one capsule or temporary crown made of PEEK or PMMA, which can be fixed to the post using the cap. The post comprises: - a first subgingival portion having vestibular, mesial, distal, and palatal surfaces, adapted to allow for the maturation of connective tissue attachment and juxitation; and - a second subgingival portion having a height adapted to the patient's occlusal height.

Surgical tools and kits for performing methods include a grommet with cylindrical shaft, cutting tip, annular flange with suture retaining anchoring fixture; a grommet jig for extending between adjacent grommets and guiding a needle therebetween; a family of needles with single and double pointed ends, reinforced eyelets, stops to limit inadvertent exiting, double shaft construction with a longitudinal gap and sharpened, slicing ends, including a “J” shape embodiment; a bone anchor with ring to secure sutures about a patient's clavicle; a tissue dissector having radially extending cones to nick taut connecting tissues; a tissue rasp having a series of crisscrossing grooves along an end; a tissue mesher comprising one or more blocks having a matrix of holes for clamping a plurality of needles and a supporting framework; and a kit device and a method of surgically inserting an internal mesh brassiere under the breast skin.

Disclosed are systems, devices and methods for laser microporation for rejuvenation of tissue of the eye, for example, regarding aging of connective tissue and rejuvenation of connective tissue by scleral rejuvenation. The systems, devices and methods disclosed herein restore physiological functions of the eye including restoring physiological accommodation or physiological pseudo-accommodation through natural physiological and biomechanical phenomena associated with natural accommodation of the eye. In some embodiments, the laser system may be configured to treat ocular tissue off axis or in a region of the eye which is distinct from the visual axis or directed away from the pupil of the eye where the gaze of the eye is.

The invention relates to the technical field of medical image processing, and discloses a breast X-ray photography auxiliary diagnosis system based on feature image selective area fusion. Comprising an image acquisition module used for acquiring a mammary gland X-ray tomographic image; the feature recognition module is used for performing feature recognition and marking on breast cancer calcification points, radial structures and circular focus high-density shadows in the breast X-ray tomographic image by using a deep learning method; the selected area fusion module is used for carrying out image synthesis on the key selected area according to the feature recognition and marking result, obtaining a synthesized image, reducing the absolute number of the images and keeping the diagnosis accuracy and sensitivity; and the three-dimensional positioning module is used for performing three-dimensional coordinate positioning on the synthesized image, outputting a focus position, dynamically optimizing 3D occupation of a focus in the synthesized image according to the focus position, analyzing and deeply learning a surrounding blood vessel and connective tissue density shadow, and outputting auxiliary diagnosis information.

This invention discloses a method for extracting sturgeon roe for caviar production. The method involves obtaining target sturgeon and determining the optimal processing time window for the target sturgeon; performing a first low-temperature pretreatment on the raw roe mass to lower its center temperature to a first target temperature range; performing rinsing and grading operations on the initially separated roe mixture to remove impurities and separating the roe into at least two grades based on particle size, obtaining roe of each grade to be cured; draining at least one grade of roe to be cured, followed by salting, and completing all steps from slaughter to salting within a second preset time period to obtain primary sturgeon roe for caviar production. This invention employs a low-temperature pretreatment combined with a suitable temperature-controlled roe-rolling process, which promotes the separation of roe from connective tissue and significantly reduces the risk of mechanical damage, thus helping to maintain the integrity of the roe particles.

To provide a tissue structure that facilitates administration of pluripotent stem cells to a disease site, and a method for forming the tissue structure.SOLUTION: A tissue structure formed by a partition wall 12 indwelled in an environment including a biological tissue, wherein the partition wall 12 includes an inner surface 14 surrounding a hollow portion 11 and a plurality of through-holes 13 opened in the inner surface 14, cells in the biological tissue enter the hollow portion 11 through the through-holes to form the tissue structure in the hollow portion 11, and the tissue structure includes a membranous fibrous connective tissue having one side surface peeled from the inner surface 14 and a sparse fibrous tissue spreading over the entire other side surface opposite to the one side surface and having pluripotent stem cells accumulated therein.SELECTED DRAWING: Figure 1

The application relates to the field of implant technology, and particularly relates to a multi-stage structure zirconium oxide abutment for regulating and controlling soft tissue sealing around an implant abutment, a cross section of the zirconium oxide abutment is an inverted isosceles trapezoid, the height of the upper half of the zirconium oxide abutment is 1-2 mm, the height of the lower half of the zirconium oxide abutment is 1-2.5 mm, the outer side surface of the lower half is uniformly distributed with a plurality of funnel-shaped blind holes, the top diameter of the blind holes is 50-150 microns, the bottom diameter is 30-50 microns, the depth is 10-200 microns, and the porosity is 10-60%. The multi-stage structure implant zirconium oxide abutment regulates and controls the attachment length of epithelium and connective tissue by using multi-stage structure design, is closer to the natural tooth structure, and improves long-term stability of implant restoration.

Dental prosthesis element comprising a microstructured surface and a surface treatment. Dental prosthesis element (1) comprising a body (4) having a microstructured surface (14), and a coating (15) covering the microstructured surface, the coating being intended to come into contact with epithelial tissue (12) and / or connective tissue (13), the coating comprising zirconium nitride. Figure for abbreviation: Figure 1

A use of a meroterpenoid compound I in the preparation of a heart failure prevention drug. By using a meroterpenoid compound I isolated and purified from the marine fungus Aspergillus terreus GZU-311 to treat mouse heart failure models induced by doxorubicin, left anterior descending coronary artery ligation, or angiotensin II, it was found that the meroterpenoid compound I can improve cardiac function in mice, reduce cardiomyocyte injury, inhibit myocardial connective tissue thickening, improve disordered arrangement of cardiomyocytes, and reduce inflammatory cell infiltration, thereby having a heart failure prevention effect. Accordingly, the use of the meroterpenoid compound I in the preparation of a heart failure prevention drug is provided. The drug source molecules that can be used for treating heart failure are enriched, which is helpful for the development of heart failure prevention drugs and clinical treatment using same.

Surgical tools and kits for performing methods include a grommet with cylindrical shaft, cutting tip, annular flange with suture retaining anchoring fixture; a grommet jig for extending between adjacent grommets and guiding a needle therebetween; a family of needles with single and double pointed ends, reinforced eyelets, stops to limit inadvertent exiting, double shaft construction with a longitudinal gap and sharpened, slicing ends, including a “J” shape embodiment; a bone anchor with ring to secure sutures about a patient's clavicle; a tissue dissector having radially extending cones to nick taut connecting tissues; a tissue rasp having a series of crisscrossing grooves along an end; a tissue mesher comprising one or more blocks having a matrix of holes for damping a plurality of needles and a supporting framework; and a kit device and a method of surgically inserting an internal mesh brassiere under the breast skin.

The invention belongs to the technical field of oyster phenotype analysis, particularly relates to an oyster gonad development level high-throughput accurate phenotype analysis method based on U-Net deep learning, and effectively solves the problems of complicated operation, high subjectivity and low precision and throughput in existing oyster gonad development phenotype identification. The method comprises the following steps: acquiring an oyster gonad tissue slice image, constructing and training a U-Net deep learning segmentation model, automatically identifying and segmenting a gonad tissue region in the image, further accurately calculating the Gonadal Proportion (GP) of the gonad tissue in the total gonad area, and realizing high-throughput and accurate quantification of the gonad development level. According to the method, the gonad tissue and the connective tissue can be accurately distinguished, objective phenotypic data are provided, key technical support is provided for gonad development character genetic parameter estimation and molecular assisted breeding of large-scale groups, and the efficiency, accuracy and practicability of gonad development phenotypic analysis are improved.

The invention provides a compound enzyme preparation for improving bullfrog quality and an application method thereof, and belongs to the technical field of food processing. The invention provides a compound enzyme preparation for improving bullfrog quality. The compound enzyme preparation comprises the following raw materials in parts by weight: 5-20 parts of bromelain, 10-20 parts of edible salt, 50-75 parts of a water-retaining agent and 2-10 parts of an antioxidant. The compound enzyme preparation provided by the invention permeates into muscular tissues through injection and rolling, and a biochemical reaction can mildly and efficiently hydrolyze muscle fiber proteins and connective tissues, so that the proteins are degraded into small-molecular polypeptides and even amino acids, meat becomes tender and smooth, the elasticity of the meat is increased, the water-retaining property is improved, and the meat has no obvious alkaline astringent taste; according to the process, twice cleaning is adopted, so that the whiteness of meat can be increased, the sensory acceptance is improved, and the similarity with the sensory evaluation result within 2 hours after live frogs are slaughtered reaches 95%.

The application discloses a traditional Chinese medicine composition for treating nodular erythema, which is prepared from the following raw materials in a proportion by weight: 3-15 parts of Bupleurum, 3-20 parts of Artemisia annua, 3-15 parts of Angelica sinensis, 3-15 parts of Radix Angelicae Pubescentis, 3-20 parts of Cynanchum, 3-15 parts of Notopterygium, 3-20 parts of Fructus Kochiae, 3-15 parts of Cnidium, 3-20 parts of Alnus, 3-10 parts of Glycyrrhiza, 3-20 parts of Salvia miltiorrhiza, 3-15 parts of Saposhnikovia divaricata, 3-15 parts of Paeonia suffruticosa, 3-10 parts of honeycomb, 3-12 parts of Tripterygium wilfordii, 5-30 parts of Crataegus pinnatifida, and 5-30 parts of Sorsastrum hemningsii. The composition can fade the skin rash and nodular erythema, has a low recurrence rate, and is superior to methylprednisolone which is commonly used in the clinic. The application can effectively treat the nodular erythema related to connective tissue disease, and has the clinical popularization and application value.

The invention discloses a biomass-based tea tree essential oil slow-release application patch for treating psoriasis and a preparation method of the biomass-based tea tree essential oil slow-release application patch. The method comprises the following steps: extracting collagen sponge from an animal connective tissue raw material, preparing a collagen solution, adding tea tree essential oil, and emulsifying to obtain a collagen Pickering emulsion; fungus strains are inoculated on a PDA solid culture medium to be cultured to obtain hyphae, then the hyphae are scraped and implanted into a PDB liquid culture medium to be cultured, and hypha membranes are obtained; finally, the mycelium membrane is coated with the collagen Pickering emulsion, so that the collagen Pickering emulsion naturally permeates into the mycelium membrane, and the biomass-based tea tree essential oil slow-release application patch is obtained after drying. The biomass-based tea tree essential oil sustained-release application patch which takes all components as biomass raw materials, has the advantages of drug sustained release, instant adhesion when encountering water and toughness when encountering water is prepared, and can be used for treating psoriasis. The sustained-release application patch has good mechanical strength, can be directly adhered to skin, has strong compliance to dynamic affected parts, and does not bring extra pain to patients.

The invention discloses a silk fibroin-based scaffold, which takes silk fibroin with chemical crosslinking and physical crosslinking as a skeleton and is loaded with levofloxacin, the chemical crosslinking is generated by catalyzing silk fibroin by hemoglobin; the physical crosslinking induces the silk fibroin to form a beta-folded structure through low temperature. The invention also provides application of the silk fibroin-based scaffold in promoting regeneration of cartilage and fibrous connective tissues and repairing long trachea defects. The silk fibroin-based stent disclosed by the invention integrates dynamic bionic mechanical properties and an infection control function, can be used for a long-segment tracheal defect in-situ repair model, and provides an innovative regenerative medicine solution for clinical repair of long-segment tracheal defects; the three problems of dynamic mechanical compatibility, efficient infection control and good tissue regeneration can be solved at the same time, and clinical transformation potential is achieved.

A device for performing a cosmetic or medical procedure and methods of operating such a device are usable for treating fibrous adhesions, such as those implicated in the formation of cosmetic or medical conditions including but not limited to cellulite. Embodiments of the disclosure have been particularly developed for targeting and disrupting fibrous adhesions to restore or improve normal physiological tissue function and / or aesthetic appearance. In at least one embodiment, the device comprises an elongate body and one or more user controllable breaking means. Each breaking means is actuatable to move between a retracted position in which the breaking means is in a collapsed configuration and an operative position in which the breaking means is in an expanded configuration suitable to break a strand of fibrous material or fibrous connective tissue.

The invention provides a degradable rib implant which comprises an arc-shaped long-strip-shaped body matched with the radian and the cross section of a human rib, the body is of a supporting structure which is internally provided with multiple holes and is communicated in a staggered mode, and the degradation rate of the supporting structure gradually decreases outwards in the radial direction from the center axis of the body. And the main body is gradually degraded from the central shaft to the outer circumferential direction along the radial direction. According to the application, the internal porous and staggered through support structure and the gradient sequential degradation design from inside to outside are adopted, so that the physiological characteristic that human body fibrous connective tissues contract inwards is ingeniously avoided; the compact fibrous connective tissue close to the rib implant in size is effectively formed under the condition that continuous mechanical supporting of the supporting structure is stably kept, and therefore the rib implant is replaced to provide effective mechanical supporting for the human body.