49 results about "Aneurysm" patented technology

Devices, systems, and methods for treating aneurysms are disclosed herein. According to some embodiments, the present technology includes a treatment system comprising a delivery shaft, a manipulation shaft slidably positioned within the lumen of the delivery shaft, and an occlusive device configured for implantation within the aneurysm. The occlusive device can comprise a plurality of filaments that are secured to one another at a proximal end of the occlusive device by a cured material. The occlusive device can comprise inner and outer layers of braided filaments, wherein the proximal end region of the inner layer has an exposed portion that extends proximally beyond the proximal end region of the outer layer, and wherein the cured material extends into and fills interstices between the braided filaments at the proximal end regions of the inner and outer layers.

The present disclosure relates generally to methods of utilizing sonosensitizers in the presence of thiamine or a derivative thereof for the purpose of cross-linking animal tissue, producing singlet oxygen within or at the site of animal tissue, or treating a condition in a subject, wherein the condition is an aneurysm, cancer, and / or a scleral condition.

The invention relates to a medical device for treating aneurysms, in particular a stent, including a compressible and expandable grid structure made up of grid elements. The grid structure has at least one closed cell ring which includes at most 12, in particular at most 10, in particular at most 8, in particular at most 6 cells directly adjacent to one another in a circumferential direction of the grid structure. The grid structure is provided at least in certain portions with a covering made of an electrospun fabric which has pores of irregular sizes. The covering includes over a surface area of 100 000 μm2 at least 10 pores which have a size of at least 15 μm2. The covering has a biocompatible, in particular antithrombogenic and / or endothelialization-promoting coating.

This invention proposes an aneurysm image segmentation method, a rupture risk prediction method, and a system. It constructs a 3D deep learning framework combining multi-view convolution and Laplacian feature pyramids. The multi-view convolution module models the 3D aneurysm structural features from multiple orthogonal directions, and a gated Laplacian frequency fusion mechanism is introduced to compensate for the loss of high-frequency detail information during downsampling, thereby improving the ability to characterize small vessels and complex boundary regions. Furthermore, the morphological features obtained from segmentation, the deep visual features of CTA images, and patient clinical information are jointly modeled. A cross-attention mechanism is used to achieve effective interaction between morphological semantics and image features, thereby completing a binary classification prediction of aneurysm rupture risk. This invention helps to fully explore the complementarity between imaging information and clinical features, more closely reflecting real clinical diagnosis and treatment processes.

The invention discloses an MMP-9-targeted MRI (Magnetic Resonance Imaging) nanoprobe and a preparation method and application thereof, the MMP-9-targeted MRI nanoprobe is represented by Gd-ACC-MAP and comprises amorphous calcium carbonate and an aptamer covalently connected to the surface of the amorphous calcium carbonate, the calcium carbonate is doped with gadolinium, and the aptamer has a nucleotide sequence as shown in SEQ ID NO: 1. The MRI nanoprobe can be used for early diagnosis of aneurysm and evaluation of rupture risk of the aneurysm.

The invention discloses a method and a system for predicting an aneurysm wall enhancement area based on hemodynamic parameters. The method comprises the following steps: acquiring a TOF-MRA image and carrying out segmentation optimization; the triangular patch grids are processed, and hemodynamic parameters are extracted; determining a tumor wall enhancement state matched with each space node on the surface of the aneurysm and prediction features influencing AWE distribution; a mapping relation model of the hemodynamic parameters and AWE is constructed, and a corresponding tumor wall enhancement state value M is calculated; analyzing the tumor wall enhancement state value M matched with each space node on the surface of the predicted aneurysm to obtain a point-level enhancement prediction distribution map; detecting a connected region of the point-level enhanced prediction distribution diagram and calculating an area; and determining and outputting an aneurysm wall enhancement state and effective enhancement area space distribution. By analyzing the correlation between the hemodynamic parameters and the aneurysm wall enhancement, efficient prediction of the aneurysm wall enhancement is realized, and the accuracy of clinical diagnosis is guaranteed.

Embodiments perform autonomous deep learning morphology analysis. At least one image, e.g., a medical image, associated with a patient is obtained. The obtained at least one image is processed using an autonomous deep learning model to extract at least one morphological parameter associated with a suspected pathology of the patient. Based on the at least one morphological parameter, an output analysis is generated. Computer-automated detection of and morphology characterization of aneurysms are provided in embodiments.

A method for generating a coil shape according to one embodiment comprises the steps of: acquiring three-dimensional data including an aneurysm region; acquiring a first image obtained by imaging a coil in a blood vessel at a first position by using a first camera; acquiring a second image obtained by imaging the coil at a second position by using a second camera; acquiring a third image obtained by imaging the coil at a third position by using the first camera; acquiring a fourth image obtained by imaging the coil at a fourth position by using the second camera; and determining a three-dimensional coil shape on the basis of the three-dimensional data, the first image, the second image, the third image, and the fourth image.

The utility model relates to a non-contact type multifunctional neurosurgery brain cotton and gelatin sponge transfer tray which comprises an upper tray and a lower tray which can be combined, a hollow cylinder is arranged at one corner of the upper tray, a pin hole column matched with the hollow cylinder through a pin shaft is arranged at one corner of the lower tray, a plurality of partition plates are arranged in the upper tray, and the partition plates are arranged in the lower tray. The upper tray is divided into a plurality of brain cotton storage areas through the partition plates, and a downward-concave circular groove used for storing an aneurysm temporary clip is formed in the lower tray. The utility model designs a double-layer opening and closing type handheld tray which can be opened in a fan-shaped manner when in use. Four kinds of brain cotton of different sizes and models can be placed on the first layer, and meanwhile brain cotton threads can be stretched and cannot be wound mutually; gelatin sponges with different sizes and models can be placed on the second layer, and an aneurysm temporary clip can be placed on the circular sunken part. When a doctor uses the device, a nurse can deliver the brain cotton and the gelatin sponge at the same time, delivery time is saved, and the device is of great significance in dealing with cerebral hemorrhage in an emergency.

A system and method are provided for treating an aneurysm or other vessel disease or defect. The present disclosure includes an expandable device for placement in a vessel, where the mechanically expandable device includes a membrane. Also disclosed is a delivery device constructed and arranged to position the expandable device such that the exterior surface of the expandable device engages with the inner surface of the vessel and maintains a fluid pathway through said vessel.

The present disclosure relates to a method for selecting a type of implantable medical device, IMD, from among a set of IMD types, the IMD being intended to be positioned in a vascular structure comprising an area of interest, the method comprising the steps of: - obtaining an image of a vascular structure comprising an area of interest; - extracting a plurality of features of the vascular structure from the obtained image; - processing, by means of a supervised learning model, the extracted features in order to obtain, for each type of IMD, a probability of compatibility quantifying a compatibility of the type of IMD with respect to the area of interest of the vascular structure; and - selecting, from among the extracted features, and according to each probability of compatibility, at least one essential feature affecting the probability of compatibility associated with each type of IMD.

The present application relates to a kind of aneurysm turbulence device, comprising: outer turbulence stent, inner turbulence stent, are woven by multiple braided wires;Inner turbulence stent is located in outer turbulence stent;The end of inner turbulence stent close to the distal end has the arc-shaped protection part of section, and protection part is set outwards to inner turbulence stent;The end of the protection part close to the distal end is connected with the end of the outer turbulence stent close to the distal end;Developing element is located in the end of the outer turbulence stent close to the proximal end, and is connected with the end of the inner turbulence stent close to the proximal end;From the direction of the distal end to the direction of the proximal end, the cross-sectional area of the outer turbulence stent gradually decreases, and the cross-sectional area of the inner turbulence stent gradually decreases;Or, the cross-sectional area of the outer turbulence stent, the cross-sectional area of the inner turbulence stent are consistent.The present application also relates to a kind of delivery system.

The invention relates to an aorta covered stent. The aorta covered stent comprises a main stent, a plurality of leg-separating stents and a skirt stent. Wherein all the leg separating supports are connected with the main support, and all the leg separating supports and the main support jointly form a blood flow channel for blood circulation. The skirt support comprises a skirt framework and a skirt covering film covering the skirt framework, the skirt support is arranged outside all the leg separating supports in a sleeving mode, one end of the skirt support is connected with the main support, and the other end of the skirt support is a free end. According to the aorta covered stent, collateral vessels on a tumor body can be blocked, II-type internal leakage is avoided, blood flow of the collateral vessels is prevented from flowing back into an aneurysm cavity, continuous flushing of the blood flow to the tumor cavity is reduced, and continuous enlargement of the tumor cavity is avoided.

This invention relates to the field of medical prediction model quality assessment technology, and particularly to a method for evaluating the bias and performance of a Kawasaki disease coronary aneurysm prediction model based on PROBAST-AI. By extracting model research information in a structured manner and using the PROBAST-AI tool to evaluate the risk of bias, the method standardizes and extracts and displays performance indicators to achieve comparability, reproducibility, and transparency among different prediction models, thereby improving the ability of clinicians and researchers to judge the quality of different models.

The application relates to a method for determining morphological parameters of a region of interest and a related product. The method comprises: performing center line extraction processing on a plurality of first regions of interest in an acquired original image to determine center lines corresponding to the plurality of first regions of interest, performing straightening processing on each two of the center lines respectively, and determining a target straightened image from at least one obtained straightened image, mapping the target straightened image to the original image, and determining morphological parameters corresponding to a second region of interest that overlaps with the plurality of first regions of interest in the original image according to a mapping relationship. The method can realize automatic measurement of an aneurysm without manual measurement, the measurement result is more accurate, and the measurement speed can be improved.

This invention provides a spring coil and its preparation method for reducing the risk of damage to the outer wall of a hemangioma. The invention features a novel structural design compared to conventional spring coils. The core characteristic of this structure is that the outer layer is a spring coil body with a secondary structure and a sparse primary structure; that is, the primary coil has a wide spacing between the coil wires, and the interior of the primary coil consists of expandable hydrogel hollow filaments. The sparse structure reduces the excessive pressure on the outer wall of the hemangioma during insertion, preventing rupture. The hollow hydrogel filament structure buffers the pressure exerted on the outer wall of the hemangioma after insertion, avoiding rupture that could worsen the patient's condition or even lead to death.

Delivery catheters for occluding aneurysms include a catheter tube extending a length. In some configurations, the catheter can include a reflux occluder section having a third diameter that is greater than a first diameter and a second diameter. The reflux occluder section is disposed along the length of the catheter tube between a proximal portion and a distal portion. Certain implementations of the catheter can include an inflatable section including a collapsed configuration having a first diameter and an inflated configuration having a second diameter sized to prevent reflux of glue within the blood vessel proximal of the inflatable section. Configurations of the catheter can include a circulation pump to create a column of fluid positioned proximate the distal end between the distal end and the glue to prevent reflux of the glue proximal of the distal end.

This invention provides an aneurysm occlusion device, comprising: an implantation part, a delivery part, a connecting part, and a release part; the release part has a connected state and a disconnected state; the implantation part includes a penetration structure, a hub, and a mesh frame, the penetration structure includes a fixing wire, the hub is disposed at the proximal end of the mesh frame, and is used to bind the fixing wire and the proximal end of the mesh frame together; the connecting part includes a first part and a second part, the first part and the second part being connected through the release part; the first part is connected to the delivery part, and the second part is combined with the first part to form the snap fastener; the proximal end of the fixing wire forms a fold, and the snap fastener is movably inserted into the fold; when the release part is in the connected state, the implantation part and the connecting part are movably connected, allowing the implantation part and the delivery part to form an angle, and restricting the separation of the implantation part and the delivery part; when the release part is in the disconnected state, the first part and the second part are separated at the release part, releasing the connection restriction between the implantation part and the delivery part, and allowing the implantation part and the delivery part to separate. This configuration, based on the movable connection between the implant and the connecting part, allows the implant and the delivery part to form an angle, which can improve the flexibility of the aneurysm embolization device implantation process and broaden the range of indications.

A vascular occlusion assembly includes a vascular occlusion device configured for implantation in an aneurysm sac, the vascular occlusion device having a delivery configuration when confined within a delivery catheter and having a deployed configuration when released from the delivery catheter into the aneurysm sac. The vascular occlusion assembly also includes a delivery wire having a distal end secured to the vascular occlusion device. The delivery wire has an electrolytically disconnectable junction adjacent the vascular occlusion device. At least a portion of the electrolytically disconnectable joint is composed of molybdenum (Mo) or a molybdenum alloy.

The invention relates to a medical implant (10) for treating a local lesion in a vessel, in particular for treating a bifurcation aneurysm, with a radially compressible and expandable support body (11) comprising at least one support mesh (12) and a compression mesh (13), each formed by interwoven filaments (20, 21), wherein the compression mesh (13) is interwoven section by section into the support mesh (12) such that at least one compression area (13a) with a first porosity (13b) and at least one support area (12a) with a second porosity (12b), which is free with respect to the compression mesh (13), is formed, whereby the ratio of the first porosity (13b) to the second porosity (12b) is between 1:1.15 and 1:2, in particular between 1:1.2 and 1:2. in particular between 1:1.4 and 1:2, in particular between 1:1.6 and 1:2, in particular between 1:1.8 and 1:2.The invention further relates to a method for manufacturing a medical implant (10) in which at least two filaments (20) are helically woven around a common longitudinal axis and form a support mesh (12), wherein, during the braiding of the filaments (20) of the support mesh (12), one or more filaments (21) forming a compaction mesh (13) are integrally woven into at least one section of the support mesh (12) such that at least one compacted area (13a) with a first porosity (13b) and at least one support area (12a) with a second porosity (12b), which is free with respect to the compaction mesh (13), is formed.

A vaso-occlusive device, includes: a vaso-occlusive structure configured for implantation in an aneurysm sac, the vaso-occlusive structure having a delivery configuration when restrained within a delivery catheter and having a deployed configuration when released from the delivery catheter into the aneurysmal sac, at least a portion of the vaso-occlusive structure being composed of a AuPtW (gold-platinum-tungsten) alloy; wherein the AuPtW alloy comprises platinum within a range between 25% and 40% by weight, and wherein the AuPtW alloy comprises tungsten within a range between 0.01% and 10% by weight.

An apparatus for treating an aneurysm includes an occlusion element configured to be releasably coupled to an elongate delivery shaft and having a distal end, a proximal end, and a longitudinal axis extending between the distal end and the proximal end, the occlusion element configured to be delivered in a collapsed configuration and further configured to expand to an expanded configuration, the occlusion element comprising an inverted mesh tube having an outer layer and an inner layer, the outer layer transitioning to the inner layer at an inversion fold located at or adjacent the distal end of the occlusion element, the inversion fold defining an inner diameter, the occlusion element further comprising a maximum outer diameter, wherein the inner diameter is between about 35% to about 85% of the maximum outer diameter, and wherein an outer diameter of the occlusion element increases along the longitudinal axis to the maximum outer diameter.

A catheter (10) for treating aneurysms is disclosed. The catheter (10) includes a liner (12) having a proximal end, a distal end, an outer surface, and an inner lumen extending from the proximal end to the distal end along a longitudinal axis A. A braid (22) is disposed on the outer surface of the liner (12) and extends from the proximal end to the distal end of the liner. The braid (22) includes multiple wires (24, 26), a first portion (24) of the wires being made from tungsten, and a second portion (26) of the wires being made from a different material. A jacket (28) is disposed around the braid and extends from the proximal end to the distal end. The braid (22) may include at least four axial sections, with the first distal section having a pick rate of approximately 330 picks per inch ("ppi").

The invention belongs to the technical field of compression hemostats, and particularly relates to an electronic self-locking radial artery compression hemostat which comprises a main body, a wrist strap, a power mechanism and a pressing plate, an annular sensor and a compression pad are installed on the pressing plate, and the pressing plate generates pressure on a hemostasis part under the compression force generated by the power mechanism; and the control panel is arranged in the main body and is connected with the power mechanism and the annular sensor. The pressing plate drives the annular sensor to be pressed on the arm of a patient, the control panel is connected with the power mechanism and the annular sensor, signals of the annular sensor can be collected, the power mechanism is controlled to move to adjust the pressing force of the pressing plate, the power mechanism is controlled to generate the pressing force, and the appropriate pressing force cannot hinder venous return; the conditions of pulse tumor, thrombus and the like are avoided, the compression force and the compression time can be automatically controlled, the operation of medical workers is facilitated, the safety of patients is guaranteed, and the device can be recycled.

The invention relates to a medical implant (10) for treating a local lesion (100) in a vessel, in particular for treating a bifurcation aneurysm (100), comprising a support body (11), which can be compressed and expanded, wherein the support body (11) comprises at least a proximal section (12) and a distal section (13), which are substantially tubular, in particular cylindrical, and connected to one another via a transition section (14), wherein the proximal section has a first porosity (12a) and the distal section (13) has a second porosity (13a), which is lower than the first porosity (12a), wherein the transition section (14) has a porosity that changes in the axial direction, wherein the first and second porosity (12a, 13a) merge into one another in the transition section (14), and wherein the transition section (14) can be positioned in the vessel in such a way that the blood flow can be at least partially diverted from the lesion (100) by the second porosity (13a) and the blood flow into an outgoing vessel (101) can be at least substantially maintained by the first porosity (12a).

An aneurysm intrasaccular implant is provided having both a braid section and a coil. The braid section is expandable from a collapsed configuration to an expanded configuration. The coil includes a proximal coil segment extending proximally from the braid section and a distal coil segment extending distally from the braid section. The implant further includes an engagement member both movable within and confined within the braid section. The engagement member is attached to one or more of the proximal coil segment or the distal coil segment.

The invention relates to the technical field of intratumoral treatment instruments, and discloses a woven intratumoral embolism device which comprises a plurality of woven balls arranged in series, each woven ball is formed by integrally weaving a plurality of wires, and the distance between every two adjacent woven balls is larger than the weaving radius of a single woven ball. The embolism device is shaped through a high-temperature heat treatment tool in the preparation process, the initial shape of the shaped embolism device is a sphere-like shape or a shape in which the packing state can be adjusted by applying tension, the embolism device is in a straightened state in a guide-in sheath, and the embolism device is self-adaptive to the aneurysm shape and achieves one-time complete embolism after being conveyed into the aneurysm through a micro catheter. The problems that due to the fact that an existing metal spring ring needs to be filled for multiple times when used for treating intracranial aneurysm, the operation time is long, the risk is high, and an existing intra-tumor embolization device is poor in aneurysm form compliance and difficult in model selection are solved.