75 results about "Intravascular stent" patented technology

The invention discloses a high-performance zinc alloy with a gradient structure and a preparation method and application thereof, and belongs to the technical field of metal material processing. The high-performance zinc alloy with the gradient structure is characterized in that the grain sizes of upper, middle and lower areas of the alloy are in fine-coarse-fine distribution, the grain sizes of the upper and lower areas are smaller than or equal to 2 microns, the grain size of the central area is 5-20 microns, and the grain size of a transition area between the upper and lower areas and the central area is 2-15 microns; meanwhile, all the areas are accompanied with MnZn13 nano precipitated phases with the size smaller than or equal to 50 nm. The alloy shows excellent deformation resistance and thermal mechanical stability, the elasticity modulus of the alloy can at least reach 125 GPa, meanwhile, the alloy shows excellent corrosion resistance, and the alloy is particularly suitable for biomedical implantation instruments such as intravascular stents and bone nails.

The invention discloses a shape memory intravascular stent capable of body temperature recovery and a preparation method thereof, and the preparation method comprises the following steps: drying polylactic acid granules, adding PEG for toughening, carrying out melt blending, adding polylactic acid fibers as a reinforcing phase, and carrying out screw extrusion to obtain a composite material. The toughness of the shape memory material is improved, the shape recovery temperature of the shape memory material is reduced, and shape recovery under the human body temperature is achieved. The intravascular stent is prepared through 3D printing, and the prepared shape memory intravascular stent has good recovery rate and fixation rate, lower recovery temperature and good biocompatibility.

The invention discloses a method for preparing a non-polymer coating of a pure magnesium intravascular stent, and relates to the technical field of medical instruments, and the method comprises the following steps: pretreatment: immersing the pure magnesium intravascular stent into a diluted hydrochloric acid solution for ultrasonic cleaning, removing a surface oxidation film and impurities, then washing the pure magnesium intravascular stent with deionized water until the pure magnesium intravascular stent is neutral, and drying the pure magnesium intravascular stent for later use; micro-arc oxidation: taking the pretreated bracket as an anode, taking a stainless steel plate as a cathode, putting the bracket and the stainless steel plate in electrolyte, applying pulse voltage for treatment, and generating a ceramic oxide layer with the thickness of 5-20 microns on the surface of the bracket; and bioactive coating: immersing the stent subjected to micro-arc oxidation into the suspension, and depositing by adopting an electrophoretic deposition method to form a hydroxyapatite coating with the thickness of 1-5 microns. According to the non-polymer coating method for the pure magnesium intravascular stent, no polymer is used in the whole coating process, inflammatory reaction possibly caused by the polymer and degradation products of the polymer is avoided, and the biological safety of the stent is improved.

A device for therapeutic ablative treatment of residual plaque on, in, and / or surrounding a stent within a blood vessel of a subject includes a jacket configured for insertion within a stent within a blood vessel of a subject. The device further includes an ultrasound transducer located within the jacket and having at least one active element oriented to deliver ultrasound energy in a radial and / or axial direction of the jacket from within the stent to ablate the residual plaque.

The invention discloses a magnesium alloy corrosion resistance prediction method based on machine learning, and relates to the technical field of metal material performance prediction.The method comprises the following steps that magnesium alloy corrosion resistance data are obtained and preprocessed, and a magnesium alloy data set is obtained; aiming at a random forest algorithm and a gradient boosting tree algorithm, training, optimizing and evaluating the prediction model by using the magnesium alloy data set to obtain an optimal prediction model; and for the optimal prediction model, inputting components and environmental parameters of the magnesium alloy, and outputting a corrosion resistance prediction value. According to the method, the prediction precision and the material design efficiency can be remarkably improved, the method is suitable for biomedical application of orthopedic implants, intravascular stents and the like, and an efficient and reliable technical path is provided for research and development of the degradable magnesium alloy.

The invention provides a self-expanding hydrogel intravascular stent and a preparation method thereof, and belongs to the technical field of medical instruments, the intravascular stent is of a hollow tubular structure, and the tube wall is of a sealed type; the intravascular stent is made of a hydrogel material. After the hydrogel stent shrinks, the size of the hydrogel stent is obviously reduced, the hydrogel stent can be delivered to a target position in a balloon intervention mode, and the hydrogel stent can stay at the target position and provide a supporting effect on the hydrogel stent due to the fact that the hydrogel stent has a self-expansion effect.

The invention discloses a functional coating, an intravascular stent and a preparation method and application of the intravascular stent. The functional coating comprises an endothelialization promoting active substance and an anti-proliferation drug; the endothelialization promoting active substance comprises at least one of polypeptide containing an RGD sequence, polypeptide containing a YIGSR sequence, polypeptide containing an REDV sequence, a beta-polypeptide polymer or a beta-polypeptide-polyester block copolymer. The functional coating disclosed by the invention can be used for surface functional modification of interventional medical devices, can selectively promote adhesion and proliferation of vascular endothelial cells at an implantation part, realizes rapid endothelialization, and can controllably release an anti-proliferation drug to inhibit excessive proliferation of vascular smooth muscle cells, so that the vascular endothelial cells are prevented from being damaged. Therefore, the risks of restenosis and advanced thrombus are effectively reduced.

The invention relates to a cross-joint intravascular stent and a preparation method thereof. The cross-joint intravascular stent comprises a first part and a second part which are distributed in the axial direction of the cross-joint intravascular stent. The first part comprises a plurality of first stent rings which are arranged at intervals in the axial direction of the joint-crossing intravascular stent and are mutually independent, and a whole-surface covering film fixedly arranged on the first stent rings; from the proximal end to the distal end, the distance between every two adjacent first stent rings is gradually increased; the second part comprises a plurality of second stent rings which are arranged at intervals in the axial direction of the joint-crossing intravascular stent and are mutually independent, and a plurality of rows of connecting membrane groups which are sequentially arranged in the axial direction of the joint-crossing intravascular stent; each row of connecting membrane group comprises a plurality of connecting membranes which are uniformly distributed in the circumferential direction of the joint-crossing intravascular stent, and the two ends of each connecting membrane are fixedly connected with the two adjacent second stent rings respectively; the width of the rods forming the first stent ring is greater than the width of the rods forming the second stent ring.

The invention relates to the technical field of medical instruments, in particular to an intravascular stent conveying system and a conveying method.The intravascular stent conveying system comprises an intravascular stent and a conveying device, and the intravascular stent comprises a telescopic tube, a main tube connected with the front end of the telescopic tube and a plurality of branch tubes connected to one side of the telescopic tube; the conveying device comprises a handle assembly, a main body bending adjusting assembly, a main body releasing assembly, a branch bending adjusting assembly, a branch releasing assembly and an outer sheath assembly. The handle assembly comprises a holding handle, a supporting rod and a guide head which are connected in sequence, and the holding handle is hollow; the outer sheath assembly is arranged on the periphery of the supporting rod in a sleeving mode and located between the holding handle and the guide head. The requirement for bending adjustment during intravascular stent implantation is met, independent release of all structures of the intravascular stent is achieved, the release mode is simple and convenient, the learning curve is short, profound hypothermia circulation arrest is avoided in the whole operation process, the operation difficulty is reduced, and damage to a patient is reduced.

The invention provides a porous cell auxetic material, an absorbable intravascular stent, a preparation device and a preparation method, and belongs to the field of medical instruments, holes in porous cells are dumbbell-shaped structural holes, and the dumbbell-shaped structural holes are transversely and vertically alternately formed in the long axis direction and also transversely and vertically alternately formed in the short axis direction; dumbbell-shaped structure holes in a transverse and vertical alternating array are formed, and the short shafts of the dumbbell-shaped structure holes are provided with anti-springback inserting and pulling abutting supporting structures; the shape of the auxetic material during expansion is maintained, shrinkage is prevented when the auxetic material is axially compressed, and lasting supporting force is provided; when the vascular stent is formed by adopting the structure, radial and axial contraction of the vascular stent is prevented, the shape of the vascular stent is maintained, reliable radial supporting force is provided, the smoothness of the blood vessel is ensured, the mechanical performance of the biological absorbable stent is improved, the use amount of the biological absorbable polymer material is reduced, and the wall thickness is reduced.

This invention relates to an endovascular stent, comprising a first sub-stent and a second sub-stent, both woven from multiple braided filaments into a mesh-like structure; the first sub-stent and the second sub-stent are coaxially arranged; a flexible element is connected at one end to one end of the first sub-stent and at the other end to one end of the second sub-stent; the flexible element has a helical or variable-diameter helical structure; when the flexible element has a variable-diameter helical structure, the outer diameter of the flexible element gradually increases and then gradually decreases from the proximal end to the distal end; by adjusting the distance between the first sub-stent and the second sub-stent, the flexible element undergoes elastic deformation, thereby adjusting the metal coverage between the first sub-stent and the second sub-stent.

The utility model discloses an intravascular stent electrode system which comprises an intravascular stent, an electrode contact, a guide wire, a signal collecting unit and a receiving coil, the intravascular stent can be implanted into a target area of an intracranial vascular system through an operation, and the electrode contact is connected to the intravascular stent and can collect intracranial signals. The guide wire can conduct stimulation current to the electrode contact and transmit signals collected by the electrode contact, the signal collecting unit is connected with the guide wire and can collect the signals transmitted by the guide wire, and the receiving coil is arranged on the signal collecting unit and forms electromotive force through a magnetic field. The electromotive force is converted by the power supply chip and then continuously supplies power to the signal collection unit and the electrode contact, so that the stable work of the signal collection unit can be maintained.

The utility model relates to the technical field of medical instruments, and discloses an intravascular stent structure capable of reducing pressure stress, the intravascular stent is of a tubular net rack structure and comprises a plurality of annular wave rods and stent connecting rods, the annular wave rods are arranged in the axial direction of the intravascular stent, a plurality of stent connecting rods are arranged on one side of each wave rod, and the stent connecting rods are arranged on the other side of each wave rod. One end of each support connecting rod is connected with an adjacent wave rod, the section of each wave rod is arranged in a wave shape, and the support is characterized in that no less than one group of pressure stress parts capable of reducing the pressure stress of the wave rods are arranged on the side surfaces of the wave rods; due to the design of the wave-shaped wave rods and the pressure stress part, the support has more elastic deformation space, when the support is stressed, the support can elastically deform to a certain degree at the fluctuation of waves and the bending part of the pressure stress part instead of directly bearing all the pressure like a rigid structure, and the elastic deformation absorbs part of the pressure, so that the stress resistance of the support is improved. Therefore, the pressure stress is reduced.

The invention discloses an antibacterial compound containing shellac nanoparticles and a preparation method of the antibacterial compound, and belongs to the technical field of medical materials. The antibacterial product is a polylactic acid-glycolic acid copolymer (PLGA) loaded shellac nanoparticle antibacterial coating or hyaluronic acid (HA) loaded shellac nanoparticle antibacterial gel. The coating and the gel prepared by the invention have excellent antibacterial performance and good biocompatibility, and the preparation method is relatively simple. The antibacterial coating can be applied to the surfaces of medical instruments such as intravascular stents, artificial heart valves, artificial blood pumps, artificial blood vessels, catheters and vein filters to improve the antibacterial performance of the medical instruments, and can also be applied to the surfaces of skin and mucosa to improve the antibacterial performance.

The present invention relates to an internal duct and fixing system (100) for branches for endovascular endoprostheses for endovascular treatment of aneurysms or dissections of the aorta, comprising (i) an endoprosthesis (200) provided with windows (210, 220, 230, 240), (ii) one or more occlusions (215, 225, 235, 245), fixed to the endoprosthesis (200) by means of suture (216, 226, 236, 246), reversibly occluding the windows (210, 220, 230, 240), and a set of fixing and duct elements (300) that forms one or more internal channels of the endoprosthesis (200), preferably in the region adjacent to one of the windows (210, 220, 230, 240). The present invention also relates to a corresponding endoprosthesis (200).

The invention relates to the technical field of laser cutting, in particular to a medical nickel-titanium alloy intravascular stent cutting device which comprises a protection cabinet body and a laser cutting machine fixedly installed on the inner wall of the protection cabinet body, an air pump is fixedly installed on the inner wall of the protection cabinet body, and the output end of the air pump is fixedly connected with a supporting inner pipe. A plurality of chutes which are uniformly arranged are formed in the outer wall of the supporting inner pipe, a fixing frame is fixedly connected to the inner walls of the chutes, a corrugated pipe is fixedly connected to the outer wall of the fixing frame, an air spraying head is fixedly connected to the outer wall of the corrugated pipe, and a fixing piece is fixedly connected to the outer wall of the air spraying head; the device has the beneficial effects that in the reciprocating process that the air spraying head stretches and then retracts, the air spraying head can gradually incline downwards during stretching, in the process, air sprayed out of the air spraying head can sweep waste located between the inner wall of the waste nickel-titanium alloy pipe fitting and the outer wall of the supporting inner pipe from top to bottom, and therefore the waste can fall off more easily.

This invention is directed to an expandable stent for implantation in a body lumen, such as an artery, and a method for making it from a single length of tubing. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common axis and interconnected by one or more links. A Y-shaped member is comprised of a U-shaped member and a link having a curved portion and a straight portion to improve the flexibility and thereby improve the fatigue performance of the Y-link junction.

The invention belongs to the technical field of biomedical materials, and provides a poly L-lactide-caprolactone composite material, a preparation method and application thereof, and an intravascular stent. The composite material is prepared from poly L-lactide-caprolactone (PLCL) and a metal oxide (one or more of ferric oxide, magnesium oxide, zinc oxide and titanium dioxide) as preparation raw materials. Compared with PLLA, the composite material provided by the invention has better strength and toughness; the metal oxide can improve the degradation speed of the polymer PLCL. Therefore, the composite material disclosed by the invention has excellent toughness, strength and degradation speed. Furthermore, particularly when the metal oxide is ferric oxide, the elongation at break and the tensile strength of the obtained composite material are remarkably improved; in addition, the in-vitro degradation rate is also obviously improved; meanwhile, the biocompatibility is excellent.

The invention provides a separable microcatheter and stent conveying system and method, and belongs to the technical field of neural intervention and vascular intervention. The system comprises a separable micro-catheter which is formed by detachably connecting a near-section micro-catheter (1) and a far-section micro-catheter (2) through a physical clamping structure; the stent conveying system comprises a conveying guide wire (3) and an intravascular stent (4), and the conveying guide wire (3) is provided with an anchoring stent (31) matched with the limiting cavity of the far-section micro catheter (2). The guide wire, the catheter and the stent conveying system are integrated, so that the vascular interventional operation process is obviously optimized. The system adopts a separable microcatheter design and a mechanical anchoring structure, so that a guide wire and a catheter do not need to be exchanged for many times in the operation process, and the number of times of instrument operation is fundamentally reduced. According to the invention, the operation time is shortened, the exposure time of an operator and a patient under X-rays is directly reduced, and the radiation dose is effectively controlled.

A bifurcated intravascular stent graft comprises primary stent segments and a primary graft sleeve, forming a main fluid channel and having a side opening therethrough. An external graft channel formed on the primary graft sleeve has a first end communicating with the side opening and an open second end outside the primary graft sleeve, thereby providing a branch flow channel from the main channel out through the side opening and external graft channel. The primary stent segments and graft sleeve engage an endoluminal surface of a main vessel and form substantially fluid-tight seals. The stent graft further comprises a secondary stent graft, which may be positioned partially within the external graft channel, through the open second end thereof, and partially within a branch vessel. The secondary stent graft engages the inner surface of the external graft channel and the endoluminal surface of the branch vessel, thereby forming substantially fluid-tight seals.

The invention provides a drug-loaded intravascular stent and a preparation method thereof.The preparation method of the drug-loaded intravascular stent comprises the steps that drug-loaded microspheres are prepared; wherein the drug-loaded microspheres comprise chitosan nanoparticles loaded with an anti-inflammatory drug, an antibacterial drug layer coating the chitosan nanoparticles, and a PLGA (poly (lactic-co-glycolic acid)) shell layer coating the antibacterial drug layer; mixing the drug-loaded microspheres with PLGA (poly (lactic-co-glycolic acid)) microspheres to prepare a blended wire rod; and according to a digital model, carrying out 3D printing on the blended wire rod to form the drug-loaded intravascular stent.

The invention relates to the technical field of medical instruments, and discloses a controllable intravascular stent conveying device which comprises a conveying sheath body, a diameter restraining assembly, a tightness adjusting assembly and a dissociation assembly, the conveying sheath body comprises an inner core and an outer sheath movably arranged outside the inner core in a sleeving mode in the axial direction of the inner core, and an intravascular stent is movably arranged between the outer sheath and the inner core in a sleeving mode; the bundle diameter assembly comprises a plurality of bundle diameter loop lines, one part of each bundle diameter loop line is wound outside the intravascular stent, the other part of each bundle diameter loop line movably penetrates through the intravascular stent to be located in the intravascular stent, the tightness adjusting assembly is arranged on the inner core, and the bundle diameter line located in the intravascular stent penetrates through the tightness adjusting assembly. The tightness adjusting assembly is used for adjusting the length of the part, wound outside the intravascular stent, of the beam diameter loop wire, and the dissociation assembly is arranged on the inner core and used for cutting off all the beam diameter loop wires at the same time or cutting off the beam diameter loop wires at different positions in sequence. The beam diameter and the release state of the intravascular stent can be controlled and adjusted, and segmental full release of the intravascular stent is achieved.

The invention provides a degradable zinc alloy intravascular stent which is of a tubular net structure and comprises a plurality of supporting rings (3) arranged in the axial direction and connecting rods (1) connected with the adjacent supporting rings (3). The supporting ring (3) is in a wave shape and is composed of a plurality of supporting rod units which are connected in sequence, each supporting rod unit comprises a first supporting rod in the middle and two arc-shaped parts connected to the two ends of the first supporting rod respectively, and wave crests or wave troughs of the supporting ring (3) are formed at the tops of the arc-shaped parts; every two adjacent supporting rod units are connected by sharing one arc-shaped part; the rod diameter (42) of the middle position (2) of the first supporting rod is W1, and the rod diameter of the first supporting rod is gradually increased from the middle position (2) of the first supporting rod to the arc-shaped parts at the two ends of the first supporting rod. The rod diameter (41) of the supporting ring (3) at the wave crest and the wave trough is W2, and W2 is larger than W1. The rod diameter (32) of the connecting rod (1) is W3, and W3 is smaller than W1.

The invention discloses a method for simulating unfolding of an intravascular stent, electronic equipment and a computer readable storage medium, and the method comprises the steps: building a simplified compression model of the intravascular stent in a microcatheter based on the size of the microcatheter, the simplified compression model comprises node particles on a simplified spiral line of a weaving wire and ghost particles on a central axis section of the intravascular stent; acquiring a blood vessel model comprising the target blood vessel segment, wherein the blood vessel model comprises a blood vessel center line and a blood vessel wall; the simplified compression model is arranged along the center line of the blood vessel, the ghost particles are located on the center line of the blood vessel, and the node particles surround the center line of the blood vessel to form a spiral structure; and carrying out geometric shape constraint and physical elastic constraint on the intravascular stent, and simulating an expansion process of the intravascular stent in the target vascular section to obtain an expansion model of the intravascular stent. According to the method provided by the embodiment of the invention, a reliable stent unfolding form can be obtained.

The invention discloses a high-performance thin-wall microtube for a magnesium alloy intravascular stent, the high-performance thin-wall microtube is prepared from magnesium alloy, and the magnesium alloy comprises the following components in percentage by mass: 1-3% of Zn, 0.2-2% of Mn and the balance of Mg. The invention also discloses a preparation method of the thin-wall microtube, which comprises the following steps: obtaining a magnesium alloy cast ingot by adopting ultrasonic smelting in a protective atmosphere, and then preparing a high-plasticity microtube extrusion blank through an extrusion-upsetting-extrusion combined extrusion process, so that the formability and stability of the extrusion microtube are improved; the magnesium alloy thin-walled tube is prepared by machining, perforating and performing hot extrusion to obtain an ultra-long hollow tube blank, and replacing the traditional multi-pass cold drawing process with single-pass hot rolling micro-tube forming. The preparation method has the beneficial effects that the prepared magnesium alloy thin-wall microtube is high in strength, excellent in plasticity and corrosion resistance and good in physiological tolerance, and the mechanical property requirements of intravascular stent forming and balloon dilatation can be met.

The invention relates to the technical field of medical materials, in particular to a medical magnesium alloy composite material and a preparation method and application thereof. The degradation rate of the medical magnesium alloy composite material is regulated and controlled by regulating and controlling the thickness of the polymer-drug-loaded nano-microsphere composite coating, the larger the thickness is, the slower the degradation rate is, and the thinner the thickness is, the faster the degradation rate is; the drug release rate of the medical magnesium alloy composite material is regulated and controlled by regulating and controlling the spatial distribution of the drug-loaded nano-microspheres in the polymer-drug-loaded nano-microsphere composite coating, so that the drug can be quickly and slowly released, and specifically, the more intensive the spatial distribution of the drug-loaded nano-microspheres (namely, the more the number of the drug-loaded nano-microspheres) is, the faster the drug is released. According to the preparation method disclosed by the invention, magnesium alloy degradation and drug release can be synergistically regulated and controlled, and the clinical application requirements of magnesium alloy intravascular stent customization, such as more sustained release energy, less sustained release energy and fast and slow degradation, are met.

The invention discloses a magnetic induction power generation intravascular stent, a treatment system and a control method thereof, and relates to the technical field of vascular intervention medical instruments. The system comprises a stent serving as an implantation unit and an in-vitro unit, the stent body is of a tubular woven structure, and a closed loop composed of conductive fibers is integrated in the stent body and used for cutting magnetic induction lines for power generation. The in-vitro unit comprises a magnetic field generating device for generating a rotating magnetic field, a driving device and a processing unit. The invention further provides a control method of the system, and the output current of the support is dynamically controlled by adjusting magnetic field parameters. Energy is transmitted through wireless magnetic induction, so that the stent generates controllable electrical stimulation on local blood vessels on the premise that a built-in battery is not needed, the problems that an existing electrified stent is short in power supply service life, uncontrollable in parameter and high in biological safety risk are effectively solved, vascular endothelial repair can be accurately promoted, abnormal proliferation of smooth muscle cells is inhibited, and the vascular endothelial repair rate is increased. The problem of restenosis in the stent is effectively prevented and treated.

The invention relates to the technical field of biomedical materials and drug delivery systems, in particular to a preparation method of a microporous polylactic acid drug-loaded coating. Comprising the following steps: coating a polylactic acid coating on the surface of a substrate; then a mixed solution of trichloromethane and N, N-dimethylformamide is used as a pore-forming solution, the coating is subjected to dipping treatment and curing under the condition that the relative humidity is 55-95%, and a microporous structure is formed; and finally, realizing drug loading in a manner of soaking or directly dissolving the drug in the pore-forming liquid. By adjusting the volume ratio (5-70%) of N, N-dimethylformamide in the mixed solvent and the environment humidity and temperature, the porous morphology of the coating from surface single-layer pores to internal through spongy pores can be dynamically regulated and controlled. The method is simple in process, mild in condition, suitable for the surfaces of medical devices in complex shapes, capable of achieving high load and controllable slow release of the medicine and capable of being used for preparing medicine-carrying medical devices such as intravascular stents and catheters.

The double-balloon intravascular stent comprises a connecting catheter, a guide wire is inserted into the middle end of the connecting catheter in a penetrating mode, the left end of the connecting catheter is fixedly connected with a first balloon, and a first air guide tube is fixedly connected between the upper end of the first balloon and the surface of the connecting catheter. A second balloon is fixedly connected to the left end of the connecting catheter and located on the right side of the first balloon, and the outer surface of the second balloon is sleeved with an expansion support. Through the arrangement of the guide wire, medical staff can conveniently guide the connecting catheter, the first balloon, the second balloon and the dilation stent into a narrow blood vessel area, needing to be dilated, of a patient in the intravascular stent implantation operation process of the patient, and through the arrangement of the pressurizing pipe, the adjusting cylinder, the air guide hole, the first air guide pipe and the first balloon, the operation is convenient, and the operation efficiency is improved. And a narrow blood vessel area can be pre-expanded, so that medical personnel can conveniently implant the expansion stent subsequently.

The invention discloses a composite material for preparing a flexible, dredged and degradable lymphatic vein anastomosis stent as well as a process and application thereof. The material is a functionally gradient composite fiber felt constructed based on a coaxial electrospinning technology, and comprises a structural skeleton matrix, an intelligent drug release system and a surface functionalization system. The structural framework matrix comprises a PLGA (poly (lactic-co-glycolic acid)) and PLLA blend, magnesium-based nanoparticles and nano tantalum powder; the intelligent drug release system comprises an environmental response type hydrogel carrier, rapamycin and heparin sodium; the surface functionalization system is covalently grafted RGD polypeptide. The preparation method comprises the steps of raw material pretreatment, composite spinning solution preparation, core-shell fiber preparation, integrated enhanced stabilization treatment, surface functional modification and sterilization. Through a unique material formula and process design, integration of multiple functions of flexible supporting, degradation controllability, intelligent drug release, endothelialization promotion, development and the like is achieved, and the problem of adaptability of a traditional intravascular stent in lymphatic vein anastomosis is effectively solved.