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1 results about "Antiproliferative Agents" patented technology
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The maintenance agents are generally 4 classes of drugs. Calcineurin Inhibitors: Tacrolimus and Cyclosporine. Antiproliferative agents: Mycophenolate Mofetil, Mycophenolate Sodium and Azathioprine. mTOR inhibitor: Sirolimus. Steroids: Prednisone.
DRG-MDM2-4 for use as a novel mouse double minute 2 (MDM2) inhibitor
The invention relates to compounds according to formula (I)and pharmaceutically acceptable derivatives thereof for use as novel inhibitors of Mouse Double Minute 2 (MDM2) activity by inhibiting interactions between MDM2 and its natural negative regulator, p53. Pharmaceutical compositions containing a compound of Formula (I), or a derivative thereof, including compositions that also contain one or more additional antiproliferative agents, can be used in methods of treating proliferative diseases, including various cancers.
Owner:BAHCESEHIR UNIVERSITY +1