11 results about "Lipoxygenase" patented technology

This invention relates to the field of chicken gizzard lining processing technology, and particularly to an active polypeptide of chicken gizzard lining, its preparation method, and functional products. The preparation method includes the following steps: mixing chicken gizzard lining powder with water and subjecting it to alkaline heat treatment to form a slurry; sequentially adding Bacillus licheniformis alkaline protease, trypsin, and pepsin to the slurry for three separate hydrolysis processes to obtain a hydrolysate; after enzyme inactivation treatment of the hydrolysate, adding Lactobacillus plantarum for fermentation to obtain a fermentation broth; sterilizing the fermentation broth and then filtering it to obtain a fermentation supernatant; sequentially subjecting the fermentation supernatant to membrane filtration, sterilization, and spray drying to obtain the active polypeptide of chicken gizzard lining. The active polypeptide of chicken gizzard lining prepared by the method of this invention exhibits alcohol dehydrogenase activating activity, AGEs inhibitory activity, albumin denaturation inhibitory activity, lipoxygenase inhibitory activity, pancreatic lipase inhibitory activity, and a beneficial bacteria proliferation promoting effect.

The invention provides black powder yeast and application of the black powder yeast in preparation of tobacco products. The invention relates to a saccharomyces uniguttatus strain SC-8, which is preserved in China General Microbiological Culture Collection Center (CGMCC) on April 16, 2025, the address of the saccharomyces uniguttatus strain SC-8 is No.3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing, and the preservation number of the saccharomyces uniguttatus strain SC-8 is CGMCC No.34232. The saccharomyces uniguttatus strain SC-8 is named as the saccharomyces uniguttatus strain SC-8. The strain can secrete lipoxygenase and degrade carotenoid and lipid substances in tobacco leaves. When the compound is used for enhanced fermentation of tobacco leaves, the content of carotenoid degradation products, cembrane degradation products, Maillard reaction products, chlorophyll degradation products, terpenoid substances and the like in the tobacco leaves can be remarkably increased, the total content of aroma components is increased by 21.2%, and the potassium-chlorine ratio is increased by 35.4%. The cigar tobacco essence can significantly improve the aroma amount, aroma richness, maturity, sweetness and combustibility of cigar tobacco leaves, reduce irritation and offensive odor, and highlight the aroma characteristics of sweet aroma, costustoot, bean aroma and the like, thereby improving the usability of the tobacco leaves.

This invention discloses a low-temperature sterilization method for feed based on the synergistic effect of a complex bioenzyme, comprising the following steps: a pretreatment stage; a dynamic reaction stage: under conditions of 40-50℃ and 60%-70% humidity, the enzyme-catalyzed reaction lasts for 30 minutes, decomposing the microbial structure; and residual enzyme activity is inactivated by short-term pulsed ultraviolet light. The complex enzymes include lysozyme, thermophilic protease, and lipoxygenase, and the nano-chitosan carrier is mixed with the complex enzymes at a mass ratio of 1:1. This invention avoids the destruction of heat-sensitive nutrients by operating at low temperature (40-50℃), achieves broad-spectrum sterilization by utilizing the synergistic effect of the complex enzymes, covering various microorganisms such as bacteria, molds, and spores, and simultaneously uses ultraviolet inactivation technology to ensure no chemical residues, protecting animal health and environmental safety. This method has low equipment cost, is easy to operate, and has no public acceptance issues, providing a green, efficient, and economical solution for the feed processing industry, significantly improving the efficiency and safety of feed sterilization technology.

This disclosure provides a method of preparing a liquid soy base, which includes the steps of: roasting whole, dehulled soybeans to a maximum temperature sufficient to inactive lipoxygenase in the soybeans; milling the roasted soybeans to a particle size from about 120 microns to about 180 microns, alternatively from about 130 microns to about 170 microns; adding the milled roasted soybeans to water to reach a desired solids content to create a milled soybean and water mixture; heating the milled roasted soybean and water mixture to pasteurize or sterilize the milled roasted soybean and water mixture and thereby generate a liquid blend; and homogenizing the liquid blend. The disclosure also provides liquid soy bases produced by the methods.

The present application belongs to the technical field of biological medicine, and particularly relates to an oral preparation of lipoxygenase of a healthy donor treatment type intestinal flora exosome package and a preparation method and application thereof. The oral preparation of lipoxygenase of a healthy donor treatment type intestinal flora exosome package comprises 0.18-0.78wt% lipoxygenase, 0.24-0.48wt% fucoidan, 1.0-2.0wt% tetrahydropyrimidine and a healthy donor treatment type intestinal flora exosome supplementing to 100% according to weight percentage. The present application adopts an ultrasonic method to prepare the lipoxygenase of a healthy donor treatment type intestinal flora exosome package, uses the treatment type intestinal flora exosome as a natural medicine carrier, successfully solves the technical problem of low oral bioavailability of lipoxygenase, and provides a new effective means for enhancing immunity and preventing and treating tumors.

The present invention relates to a Chlamydomonas insulata-derived 15S-lipoxygenase for simultaneously producing resolvin D5 and protectin Dx. More specifically, provided are: a composition for producing resolvin D5 and protectin Dx, the composition comprising, as an active ingredient, a Chlamydomonas insulata-derived 15S-lipoxygenase or a gene encoding same; a method for producing resolvin D5 and protectin Dx, the method comprising the step of treating a substrate with the composition; a recombinant expression vector for producing resolvin D5 and protectin Dx, the recombinant expression vector comprising the 15S-lipoxygenase gene; and a transformant in which a host cell is transformed with the recombinant expression vector.

The present disclosure describes that the 15-lipoxygenase (15-LO) product 4-hydroxynonenal (4HNE or 4-HNE) post-translationally modifies LRRK2 and is believed to induce a pathologically elevated, chronic LRRK2 kinase activity associated with a LRRK2 mediated disease or condition, e.g., Parkinson's disease or frontotemporal dementia. Production of LRRK2-4HNE adducts, e.g., LRRK2 Cys2024-4HNE and / or LRRK2 Cys2025-4HNE adduct described herein, may be an indication of a LRRK2 mediated disease or condition. Inhibiting the production of excessive 4HNE in cells by 15-LO inhibitors converted an elevated LRRK2 activity to a normal basal LRRK2 activity level as demonstrated in cellular experiments in the Examples. The 15-LO inhibition of 4HNE production is believed to only remove elevated LRRK2 activity associated with LRRK2 mediated diseases or conditions and not normal LRRK2 activity that may be required for other cellular functions. Accordingly, 15-LO inhibition of elevated LRRK2 activity and / or expression may afford a safe and effective treatment for LRRK2 mediated diseases or conditions.

The invention belongs to the technical field of medicines for treating inflammatory skin diseases, and discloses application of kinsenoside in preparation of medicines for treating skin inflammatory diseases, the structural formula of kinsenoside is shown in the specification, and kinsenoside can be particularly used for preparing medicines for treating psoriasis. According to the application, the kinsenoside is applied to the preparation of the medicine for treating the skin inflammatory diseases, particularly the medicine for treating the psoriasis for the first time, the kinsenoside can up-regulate arachidonate 15-lipoxygenase (ALOX15) in the skin so as to intervene the psoriasis, and a candidate medicine is provided for clinically developing natural products for treating the skin inflammatory diseases including the psoriasis.

The invention relates to a wall breaking machine, a control method and device thereof and computer equipment. The method comprises the following steps: in response to a wall breaking machine starting instruction, identifying the type of to-be-processed food; if the type of the food to be processed is beans, a blue light source irradiation function is started; if the type of the to-be-processed food is not beans, identifying whether the type of the to-be-processed food is a vitamin C-containing type; and if the type of the food to be processed is the vitamin C-containing type, starting a red light source irradiation function. Thus, by identifying the type of the food to be processed, when the food is determined to be beans, the irradiation function of the blue light source is started, the blue light source starts the activity of targeted activation lipoxygenase, and the content of hexanal and hexanol products is reduced, so that the beany flavor is removed; when the beans are determined to be non-beans and are judged to contain vitamin C, the irradiation function of the red light source is started, and the red light source excites Cu / Zn-superoxide dismutase in a targeted manner, so that the generation amount is reduced, ascorbic acid oxidase is inhibited, and the vitamin C is further protected from being damaged.

The present disclosure provides compounds, compositions comprising them, and pharmaceutical uses thereof, for example, compositions suitable for the treatment of 12 lipoxygenase (12-LOX) mediated diseases.

The invention relates to a baking technology of fragrant tea leaves, and belongs to the technical field of tea leaf processing. In the tea leaf preparation process, supercritical CO2 extraction is used, activated carbon adsorption is used for effectively removing caffeine in tea leaves, meanwhile, activated carbon is soaked with an ethanol solution and then alternately soaked with acid and alkali, the removal efficiency of caffeine in the tea leaves can be improved, and the bitterness of the tea leaves is remarkably reduced; besides, cellulase, catalase and lipoxygenase are further selected for composite synergistic fermentation, the taste and fragrance of the tea leaves are obviously improved, the fermented leaves are subjected to fixation, rolling, baking, spreading and cooling and then mixed with the shaddock peel to be baked, and the taste and fragrance of the tea leaves can be obviously improved.