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577 results about "Caffeine" patented technology

This medication is used occasionally to help you stay awake and alert when you are feeling tired and/or drowsy.

Pilot fatigue detection and alert technology

Examples relate to a fatigue detection system to monitor and assess pilot fatigue levels during flight operations. An example system includes a wearable biometric sensor (WBS) integrated into a wristband that captures biometric data from the pilot. A processor analyzes the captured data to determine the pilot's fatigue level. When this level exceeds a predetermined threshold, the system provides an alert to the pilot through a haptic feedback mechanism in the wristband. Additionally, the system generates personalized fatigue mitigation advice, which is displayed on an electronic flight bag (EFB) application accessible to the pilot. The advice may include recommendations for taking a controlled rest, consuming caffeine, or engaging in physical activity. The system enhances flight safety by providing real-time alerts and actionable advice to combat pilot fatigue.
Owner:KANJILAL ANIJEET +3

Malus spectabilis flower and leaf tea and preparation method thereof

The invention belongs to the field of health-care tea preparation, and particularly relates to begonia flower and leaf tea and a preparation method thereof. Triticale bran pulp is mixed with smashed begonia leaves, the mixture is fermented through a flavor improving fermentation inoculant and then mixed with an anti-oxidation and excitation-inhibiting solution, and the prepared low-caffeine tea base material does not cause insomnia, has the characteristics of inhibiting inflammation and resisting oxidation, protects nerve cells from being damaged, and is suitable for being used as a health-care tea base material. The honeysuckle, the endive and the soybeans are ground into thick liquid, then mixed with the repair juice, centrifuged to remove precipitates, and then frozen nano spray drying is carried out, so that the obtained nano particles for protecting the liver and the kidney and promoting circulation are higher in stability and can accelerate absorption of small intestines; a taste regulator obtained by mixing grain mucus with tartaric acid, ethyl maltol, methyl anthranilate and sorbic acid is sprayed on the surface of a begonia flower and leaf tea mixture, and the prepared begonia flower and leaf tea does not affect sleep after being drunk, does not damage livers and kidneys in organisms, is good in taste and is easy to drink for a long time.
Owner:新疆玛禾生态农庄有限责任公司

Dihydroquercetin caffeine eutectic crystal as well as preparation method and application thereof

The invention provides a dihydroquercetin caffeine eutectic crystal and a preparation method and application thereof, and belongs to the technical field of eutectic crystal manufacturing. The structural formula of the dihydroquercetin caffeine eutectic crystal is as shown in formula I. The dihydroquercetin caffeine eutectic crystal has excellent water solubility, so that the dihydroquercetin caffeine eutectic crystal has ideal compatibility and bioavailability.
Owner:SHENZHEN SHINESKY BIOLOGICAL TECH CO LTD

Anti-hair-loss composition, preparation thereof and application of anti-hair-loss composition in hair washing and caring products

The invention discloses an anti-hair-loss composition, preparation thereof and application of the anti-hair-loss composition in hair washing and caring products, and belongs to the field of cosmetic preparation. The method for preparing the anti-hair-loss composition with the good and lasting anti-hair-loss effect comprises the following steps: (1) uniformly mixing arginine and citric acid, then adding diaminopyrimidine oxide, and continuously and uniformly mixing to form a mixture A; (2) uniformly mixing azelaic acid, nicotinamide and butanediol to form a mixture B; (3) uniformly mixing the mixture A, the mixture B, caffeine, a sanguisorba officinalis root extract, a green tea extract and a cacumen biotae extract to obtain the anti-hair loss composition. The anti-hair loss composition prepared by the invention is simple in component and simple in preparation process; the effect is lasting, and the anti-hair loss effect is good.
Owner:WUXI ZHIYAN BIOTECHNOLOGY CO LTD

External composition for hair growth regulation and preparation method thereof

The invention relates to an external composition for hair growth regulation and a preparation method thereof, and belongs to the technical field of cosmetics and medicines. The composition disclosed by the invention comprises nano mesoporous carbon for enhancing permeation, various surface functional modifications on the nano mesoporous carbon, minoxidil, protein fragments, polypeptides, oligopeptides, amino acids, dutasteride, bimatoprost, traditional Chinese medicine extracts, vitamins, caffeine, nucleosides, growth factors and various auxiliary functional components. Wherein the pore diameter of mesopores of the nano mesoporous carbon for enhancing permeation is 2-30 nm, the total pore volume of the mesopores is 1.5-3.5 cm < 3 > / g, and the particle size of the nano mesoporous carbon is 50-200 nm. The prepared nano mesoporous carbon is granular, controllable in size, stable in structure, free of irritation to skin, capable of keeping inert to various active ingredients in the composition, capable of enhancing absorption and permeation of other ingredients on the skin, wide in application range, capable of compounding various types of active ingredients and high in biological safety.
Owner:GUANGZHOU MOXI TECH CO LTD

Hair follicle targeting nano-liposome anti-hair loss and hair growth compound preparation

The invention discloses a hair follicle targeting nano-liposome anti-hair loss and hair growth compound preparation. The compound preparation is prepared from the following raw materials in parts by mass: 70 to 85 parts of bionic liposome carrier and 15 to 30 parts of active ingredients, the bionic liposome carrier is prepared from 50 to 60 parts of egg yolk lecithin, 15 to 20 parts of pH sensitive phospholipid DOPE, 10 to 15 parts of cholesterol and 5 to 10 parts of mesenchymal stem cell exosome membrane protein; the active ingredients comprise 5 to 10 parts of minoxidil, 3 to 5 parts of caffeine, 0.5 to 1 part of miR-218-5p, 1 to 2 parts of biotin and 2 to 3 parts of quercetin; the average particle size of the nano-liposome formed by the bionic liposome carrier is 120-180nm, and the polydispersity index (PDI) is less than or equal to 0.15. The invention relates to the technical field of biological medicines, in particular to a hair follicle-targeted nano-liposome anti-hair loss and hair growth compound preparation, which has the following advantages due to the adoption of the technical scheme: accurate targeted delivery is realized, and the treatment safety and accuracy are improved; intelligent response release is achieved, and the local microenvironment of hair follicles is optimized; the multi-target synergistic effect breaks through the limitation of single treatment.
Owner:李彦非

Gustation receptor derived peptide capable of effectively detecting caffeine and biosensor

The invention discloses a taste receptor derived peptide capable of effectively detecting caffeine and a biosensor, and belongs to the technical field of biosensors. Currently, traditional spectrum and chromatography on which caffeine detection depends have the problems of expensive instruments, time-consuming detection, complex procedures and the like, and a sensor based on a taste receptor is also faced with the limitations of high cost, complex preparation process and easy inactivation of the receptor. In order to solve the problem, the taste receptor derived peptide provided by the invention has an amino acid sequence as shown in SEQ ID NO: 4, the biosensor comprises a substrate and a disc interdigital electrode, and a carbon nanotube is firmly attached to the electrode and is connected with the taste receptor derived peptide. The biosensor can specifically detect caffeine in a beverage, has no response to other substances, and has application potential in the fields of food quality control, clinical drug monitoring, public health safety assessment and the like.
Owner:NORTHEAST FORESTRY UNIV

Compositions and methods for treating and preventing hair loss

Described herein are compositions for promoting hair growth and / or treating or preventing hair loss in a mammalian subject. In certain embodiments, the mammalian subject is a human male or a human female. Methods of making and using the same are also described. The compositions in various embodiments may comprise: a tea extract which may comprise a polyphenol, e.g., epigallocatechin gallate; an extract from Larix europaea which may comprise the flavonoid taxifolin; a natural ingredient that antagonizes or mitigates the proliferation of Gram-positive bacteria in the hair shaft passageway; compounds including zinc chloride and / or hexamidine diisethionate; follicle stimulator. e.g., caffeine, an ingredient that improves the health of the dermis. e.g., sodium hyaluronate; and / or ingredients specifically tailored for male or female subjects, e.g., Serenoa serrulata fruit extract or extract of Pterocarpus marsupium.
Owner:VIAS PARTNERS LLC

Compound paracetamol and amantadine hydrochloride capsule and preparation method thereof

PendingCN119235812Areduce contentAntipyreticAnalgesicsChlorobenzeneChlorpheniramine Maleate
The invention discloses a compound paracetamol and amantadine hydrochloride capsule which is prepared from the following components in parts by weight: 250 parts of paracetamol, 100 parts of amantadine hydrochloride, 2 parts of chlorpheniramine maleate, 10 parts of calculus bovis factitius, 15 parts of caffeine, 20 parts of propyl gallate, a filler, a disintegrating agent, an adhesive and a lubricant. Propyl gallate is applied to prevent amantadine hydrochloride from being degraded into 2-aminoadamantane, the content of the impurity 2-aminoadamantane is reduced, and the filler, the disintegrating agent, the adhesive and the lubricant in a certain proportion are used for granulation, so that the problem that the dissolution rate is unqualified in the prior art is solved.
Owner:NANJING YIHENG PHARM CO LTD

Caffeine-free tea-flavored concentrated solution

The invention discloses a caffeine-free tea-flavored concentrated solution, and relates to the field of food processing. The caffeine-free tea-flavored concentrated solution comprises an aroma extracting solution A and a taste concentrated solution B. The aroma extracting solution A and the taste concentrated solution B are compounded, blended and refined to prepare the caffeine-free tea-flavored concentrated solution. The aroma extracting solution A is prepared through the steps of raw material treatment, low-temperature vacuum steam extraction and condensation collection, and the taste concentrated solution B is prepared through the steps of Roebos tea pretreatment, water extraction concentration and enzymolysis synergy. According to the caffeine-free tea flavor concentrated solution, through the synergistic effect of supercritical carbon dioxide fragrance removal and natural caffeine-free Roibos tea, the caffeine content of a final product is lower than the detection limit and is far lower than the residue level of a traditional method. The low-temperature vacuum steam extraction avoids degradation of heat-sensitive aroma components, and the condensation collection technology is combined, so that the retention rate of volatile aroma components is high and is obviously superior to that of a supercritical carbon dioxide method.
Owner:SHANGHAI XUMEI FOOD TECH CO LTD +2

Momordica grosvenori instant coffee beverage for assisting in reducing uric acid and preparation method of momordica grosvenori instant coffee beverage

The invention discloses a siraitia grosvenorii instant coffee beverage assisting in reducing uric acid and a preparation method thereof, and belongs to the technical field of food based on the theory of homology of medicine and food. The coffee beverage is composed of instant coffee powder, a compound sweetening agent, coconut milk powder, milk powder and composite herbal powder in a specific proportion. The compound herbal powder is composed of poria cocos, peach kernels, dried tangerine or orange peel and momordica grosvenori which are selected from a medicinal and edible substance catalog. The herbal active ingredients and a coffee system are deeply fused by optimizing an extraction process, the dual regulation effects of inhibiting xanthine oxidase and promoting uric acid excretion are synergistically exerted, and the technical contradiction that common caffeine possibly affects uric acid excretion is effectively solved. The zebra fish in-vivo experiment proves that the level of uric acid can be remarkably reduced (Plt: 0.001), the improvement rate is as high as 17.63%, and a safe and effective daily diet intervention scheme is provided for people with hyperuricemia while the coffee flavor and convenience are provided.
Owner:GUANGXI ZHUANGYUAN PHARM TECH CO LTD

Anti-fatigue refreshing functional chewing gum containing natural active ingredients

The invention relates to an anti-fatigue refreshing functional chewing gum containing natural active ingredients, which relates to the technical field of food, and comprises a gum base, a natural sweetening agent and an active ingredient mixture, the mustard extract and coffee are innovatively combined to form a dual-channel nerve activation mechanism, the mustard extract realizes instant refreshing through a targeted oral trigeminal nerve TRPA1 ion channel, caffeine maintains continuous excitation through antagonism of a central adenosine receptor, and the space-time cooperation of the mustard extract and the coffee breaks through the limitation of a single path. Meanwhile, a rhodiola rosea extract, a sea-buckthorn extract, an American ginseng extract and astragalus polysaccharide are compounded, so that a triple anti-fatigue physiological barrier with functions of nerve regulation, oxidative stress inhibition and energy metabolism optimization is formed. In the preparation process, a microcapsule embedding technology is adopted to control slow release of mustard active ingredients, menthol flavor is combined to synergistically trigger TRP channel dual activation, and unification of efficacy and palatability is achieved.
Owner:吴枝富

Composition with sensitive skin repairing and anti-aging functions as well as emulsion and application thereof

The invention discloses a composition with sensitive skin repairing and anti-aging functions as well as an emulsion and application of the composition, and belongs to the technical field of cosmetics. The composition specifically comprises a pseudoalteromonas fermentation product extract, collagen, palmitoyl tripeptide-5, acetylchitosamine, sodium hyaluronate, silanetriol, caffeine and acetyl hexapeptide-8, and can promote the generation of laminin-5 and integrin beta1, promote the vitality of keratinocytes and fibroblasts, inhibit the growth of the keratinocytes and the fibroblasts, inhibit the growth of the keratinocytes and the fibroblasts, inhibit the growth of the keratinocytes and the fibroblasts, and promote the growth of the keratinocytes and the fibroblasts. The generation of inflammatory factors (IL-6) is inhibited; the generation of collagen IV and collagen VII is promoted; the invention further provides an emulsion prepared from the composition, and the optimal formula of the emulsion is obtained through optimization. The active composition disclosed by the invention has a wide application prospect in the field of cosmetics, and particularly has important significance in sensitive skin repair and anti-aging directions.
Owner:QINGDAO YOUDO BIOENG +1

Fermented beverage capable of relieving fatigue and preparation method of fermented beverage

The invention provides a fermented beverage capable of relieving fatigue and a preparation method of the fermented beverage, and relates to the technical field of functional beverages, and the IPC classification number belongs to A23L2. The fermented beverage is prepared from a radix astragali fermentation extract, a radix platycodonis extract, L-arginine, taurine, inositol, caffeine, nicotinamide, vitamin B6, L-lysine hydrochloride, pyrroloquinoline quinone and auxiliary materials. The astragalus mongholicus fermentation extract can improve the ATP generation efficiency, reduce lactic acid accumulation after exercise, relieve damage of oxidative stress to muscle and nerve cells and reduce immunosuppression caused by fatigue; the platycodon grandiflorum extract has the effects of refreshing mind and restoring consciousness, improving cognitive function decline caused by central fatigue, enhancing capillary permeability and promoting removal of metabolic wastes. The radix astragali fermentation extract and the radix platycodonis extract are compounded to achieve a synergistic effect, so that the composition has an excellent anti-fatigue effect. Under the combined action of all the components, fatigue is relieved, energy is rapidly supplemented, and physical strength is recovered.
Owner:GUANGZHOU EASTROC BEVERAGE

Essence with repairing and moisturizing functions and preparation method thereof

The invention relates to the technical field of skin care products, in particular to essence with repairing and moisturizing functions and a preparation method thereof.The essence is prepared from, by mass, 0.3%-0.7% of active caffeine, 5%-10% of humectants, 0.3%-0.6% of preservatives, 15%-25% of skin activating ingredients, 0.05%-0.5% of bisabolol, 0.2%-0.6% of stabilizers, 2%-4% of potassium azelaic diglycinate, 0.05%-0.3% of vitamin E and the balance water. And the balance of deionized water. The essence has repairing and moisturizing functions, is non-toxic, harmless and non-irritant to skin, and can relieve facial acnes and inhibit growth and reproduction of propionibacterium acnes.
Owner:HENAN BEJIT TECH DEV CO LTD

Compositions and methods to potentiate musculoskeletal effect of one or more anabolic amino acids on bone health

A method of improving and / or enhancing at least one of bone mineralization, bone strength, bone mass, and bone mineral density in an individual in need thereof, the method comprising administering to the individual a composition comprising one or more anabolic amino acids, and the composition further comprising one or more autophagy-inducing compounds. In one embodiment, the one or more autophagy-inducing compounds are selected from the group consisting of thymol, carvacrol, spermidine, urolithin (e.g., Urolithin A, B or D), rapamycin, Torin1, valproic acid, polyphenols (e.g., resveratrol), caffeine, metformin, 5′ AMP-activated protein kinase (AMPK) activators, L-type calcium channel inhibitors, ketones (e.g. beta-hydroxybutyrate, ketone salts, or ketone ester derivatives), 4,4′-dimethoxychalcone and mixtures thereof.
Owner:SOCIETE DES PRODUITS NESTLE SA

Fermented caffeine eye cream composition and eye cream containing same

The invention discloses a fermented caffeine eye cream composition. Comprising the following components in parts by weight: 30 to 80 parts of a fermentation composition, 1 to 5 parts of caffeine, 0.1 to 0.3 part of hydroxypropyl tetrahydropyrantriol, 0.5 to 2 parts of nicotinamide, 0.1 to 1 part of squalane, 0.01 to 0.5 part of a ceramide composition, 0.005 to 0.05 part of dipeptide diaminobutyryl benzyl amide diacetate, 0.005 to 0.05 part of a polypeptide composition, 0.01 to 0.5 part of carnosine, 0.01 to 0.5 part of tetrahydromethylpyrimidine carboxylic acid and 3 to 12 parts of a plant extract. The invention also discloses an eye cream containing the eye cream composition. The fermented caffeine eye cream composition provided by the invention can effectively smooth the skin surface, and is beneficial to preventing and comforting aging, improving skin elasticity, improving dark circles, relieving edema and removing under-eye puffiness.
Owner:GUANGDONG BAILICHEN BIOTECHNOLOGY CO LTD

Lightweight tea caffeine herbal beverage and preparation method thereof

The invention provides a light-nourishing tea and caffeine herbal beverage and a preparation method thereof.The beverage is prepared from tea leaves, coffee pericarp and herbaceous plants. According to the method, firstly, the natural fragrance in the coffee pericarp is improved through a far infrared fragrance improving technology; the dissolution rate of nutritional active ingredients in the coffee pericarp and herbaceous plants is promoted through a wall-breaking slow boiling technology, the shelf life stability of the beverage is improved through a low-temperature micropore refined filtration technology, and the defect that the tea fragrance of the beverage is unstable is overcome through a supercritical extraction technology. The product obtained by the preparation method not only contains natural aroma components of the tea caffeine raw material, organic acids, tea polyphenols, amino acids, flavonoids, polysaccharides and other components beneficial to human bodies, but also has rich health-preserving effects of the herbaceous plant raw material, such as oxidation resistance, inflammation resistance, immunity regulation and the like, and is suitable for large-scale popularization and sales in the market.
Owner:SHENZHEN SHENBAO HUACHENG TECH

Preparation process for extracting high-content chlorogenic acid from green coffee broken rice

The invention relates to a preparation process for extracting high-content chlorogenic acid from green coffee broken rice. According to the process, a non-organic solvent method is adopted, the low-caffeine green coffee bean extract is prepared through the steps of raw material pretreatment, low-temperature ultrasonic enzymolysis extraction, column chromatography, concentration, spray drying and the like, and active ingredients of various caffeoylquinic acid substances such as chlorogenic acid are enriched. In the preparation process, a protective agent is used for avoiding attenuation of chlorogenic acid in heating and air, a resin gradient separation method is used for enriching chlorogenic acid to remove caffeine, and a UPLC technology is used for realizing simultaneous quantitative detection of various caffeoylquinic acid components. The preparation process has the advantages of no organic solvent residue, high effective component content, high separation efficiency, safety, environmental protection, and suitableness for large-scale production. The final product not only contains high chlorogenic acid and low caffeine, but also is rich in caffeoylquinic acid substances and other active ingredients, has better flavor than market products, and is lower in application difficulty in the food and beverage industry.
Owner:ZHEJIANG TIANCAO BIOTECHNOLOGY CO LTD

Systems and methods for selectively adding additional ingredients through a secondary compartment to a liquid beverage

An apparatus and method for selectively adding additional ingredients, e.g., liquids or powders such as caffeine, vitamins, flavorings, supplements, to a liquid beverage in a container, the container includes at least one side portion, a bottom portion attached thereto, and a top portion attached to the at least one side portion, an opening mechanism for selective opening of a lid over an aperture, a first compartment located within the container and in fluid connection with the aperture, and at least one secondary compartment each having a top portion and a bottom portion located on the top portion of the container, wherein the at least one secondary compartment is external and adjacent to the first compartment; wherein pressure on the top portion of the at least one secondary compartment releases an ingredient from the at least one secondary compartment in the first compartment within the container.
Owner:HART DYNAMICS LLC

Preparation method of tea leaf extract rich in tea aroma components, tea polyphenols and caffeine

The invention discloses a preparation method of a tea leaf extract rich in tea aroma components, tea polyphenols and caffeine. The method comprises the following steps: firstly, extracting and separating aroma components in tea leaves by using a supercritical CO2 extraction technology, extracting residual residues by using ethanol, separating and enriching by using a normal-phase / reversed-phase column chromatography technology, simultaneously obtaining tea polyphenol and caffeine, and removing other ineffective components, thereby obtaining the tea leaf extract with relatively strong antioxidant, whitening and soothing effects; the color is appropriate, the fragrance is stronger, the stability is better, the activity is better, and the application range is wider; moreover, the whole extraction operation process is simple, and large-scale production is easy, so that the method can be widely applied to products such as cosmetics, shampoo, shower gel, facial cleanser, food and beverage, health care products and the like.
Owner:TSINGHUA SHENZHEN INTERNATIONAL GRADUATE SCHOOL +1

Methylthioninium salt-containing compositions and methods

PCT designated stageWO2025183757A1Nervous disorderDispersion deliveryChlorideTheanine
Methylthioninium salt-containing compositions can include methylthioninium chloride (Methylene Blue) in combination with additional compounds that work cooperatively and / or synergistically to treat various conditions. In one example, the methylthioninium salt-containing composition can include methylthioninium chloride, caffeine, and L-theanine. The methylthioninium chloride and the caffeine can be present at a weight ratio from about 1:75 to about 1:4. the methylthioninium chloride and the L-theanine can be present at a weight ratio from about 1 :200 to about 1:10, and the caffeine and the L- theanine can be present at a weight ratio from about 1 :5 to about 1:1.
Owner:LOPEZ DARREN +1

Anti-hair loss hair care essence and preparation method thereof

PendingCN119679685ACosmetic preparationsHair cosmeticsBiotechnologySaw palmetto extract
The invention discloses an anti-hair loss hair care essence. The anti-hair loss hair care essence comprises the following raw materials: 10.5%-28% of a plant extract, 0.3%-1% of vitamins, 3%-8% of proteins and amino acids, 5%-14% of natural oils and fats, 70%-85% of a solvent and 1.6%-4.3% of an additive, the plant extract comprises 1%-3% of an angelica sinensis extract, 1%-4% of a cacumen biotae extract, 3%-5% of a polygonum multiflorum extract, 2%-4% of a ginger extract, 1%-3% of a ginseng extract, 0.8%-3% of a rosemary extract, 1%-3% of a saw palmetto extract, 0.2%-1% of caffeine and 0.5%-2% of a camellia nitidissima flower and leaf extract. The hair conditioner is reasonable in design, can reduce hair loss by nourishing hair follicles, regulating scalp grease secretion, improving scalp blood circulation and the like, can provide nutrition required by hair growth, activate the hair follicles, promote hair regeneration and make hair thicker, can deeply moisten hair, repair damaged hair quality and improve the problems of dryness, roughness, furcation and the like of the hair, and has a good application prospect. The hair is healthier and shiny.
Owner:GUANGDONG JINSHI BIOTECHNOLOGY CO LTD

Method for increasing caffeine content and crude fat content in coffee extract by combining subcritical water extraction with ethanol

The invention discloses a method for increasing caffeine content and crude fat content in coffee extract liquor through combination of subcritical water extraction and ethanol. The method comprises the following steps: mixing coffee bean powder with an ethanol water solution, sequentially carrying out programmed heating, staged pressure and temperature control subcritical water extraction, cooling, carrying out solid-liquid separation, and carrying out reduced pressure distillation on filtrate to recover ethanol, thereby finally obtaining the coffee extract. Through ethanol concentration regulation and control in combination with staged temperature control, the content of crude fat is increased to be greater than or equal to 12mg / g while the content of caffeine is greater than or equal to 18mg / g. According to the method, the defect of low crude fat content in traditional subcritical extraction is overcome through the synergistic effect of polarity adjustment of ethanol and subcritical water, and efficient enrichment of two components is realized.
Owner:SOUTH CHINA UNIV OF TECH

Caffeine removal method of unroasted coffee beans

PendingJP2025030686AGreen coffee treatmentCoffee alkaloid content reductionBiotechnologyCaffeine
To provide a caffeine removal method of unroasted coffee beans capable of removing caffeine by extracting caffeine from the unroasted coffee beans, by suppressing deterioration of original flavor of coffee beans caused by removal of lipid or the like.SOLUTION: A removal method of caffeine from unroasted coffee beans includes: moistening the unroasted coffee beans by bringing them into contact with water; storing the moistened unroasted coffee beans in an extraction vessel 10; obtaining water-containing carbon dioxide by bringing the carbon dioxide from a cylinder 12 into contact with water (vessel 16); introducing the water-containing carbon dioxide into the extraction vessel 10 to contact the moistened unroasted coffee beans; pressurizing the carbon dioxide to a supercritical state; reducing the pressure to a non-supercritical state; and repeatedly cycling the pressurization and depressurization several times to extract and remove caffeine from the unroasted coffee beans.SELECTED DRAWING: Figure 1
Owner:TOHOKU UNIV

Cosmetic composition for fading dark circles of eyes, eye cream and preparation method

The invention belongs to the technical field of cosmetics, and particularly discloses a cosmetic composition and eye cream for fading dark circles of eyes and a preparation method, the cosmetic composition is prepared from the following raw materials in parts by weight: 0.1-2 parts of Mailong eight-treasure raw powder, 0.1-2 parts of sialic acid, 0.1-5 parts of caffeine, 0.01-1 part of glucosyl hesperidin, 0.01-2 parts of mulberry root bark extract and 0.1-5 parts of botryine. The cosmetic composition provided by the invention can effectively improve the skin microcirculation around eyes, enhance the elasticity of the skin around eyes and reduce hyperpigmentation, so that dark circles around the eyes are obviously faded, and meanwhile, the cosmetic composition also has the advantages of small irritation and high safety; the prepared eye cream is high in stability and small in irritation; meanwhile, the whole process of the eye cream is simple, easy to implement and suitable for industrial production and application.
Owner:HUBEI MA YINGLONG BABAO BIOTECHNOLOGY CO LTD

Ultrasonic extraction equipment for caffeine in tea leaves

The invention discloses ultrasonic extraction equipment for caffeine in tea leaves, which comprises a kettle body and a vibration box hoisted at the axis of the inner side of the kettle body, a plurality of uniformly distributed ultrasonic generators are arranged in the vibration box, the bottom of the inner side of the kettle body is fixedly connected with a grinding disc, and an opposite grinding piece is movably arranged at the position, deviating from the axis, above the grinding disc. By combining ultrasonic treatment with mechanical crushing, the crushing efficiency and the crushing degree of tea leaves are improved, the stirring piece can move in the direction of the supporting rod, the tea leaves floating on the liquid level or above can be conveyed downwards in cooperation with the blade design and the rotating motion of the stirring piece, meanwhile, materials at the bottom are overturned upwards to be homogenized, and the crushing efficiency is improved. The movement of the opposite-grinding piece can push tea leaves, avoid material accumulation, prevent repeated grinding of the same batch of tea leaves, and realize functional linkage of grinding operation, material collection and pushing, stirring and directional material conveying under the same driving traction, so that the tea leaves can be uniformly dispersed, and the tea leaves can be fully decomposed under the action of high-frequency sound waves.
Owner:HEZHOU UNIV

Compositions containing a non-caffeine stimulant or nootropic and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance

Disclosed herein are compositions that include a combination of: (1) a non-caffeine stimulant or nootropic (e.g., paraxanthine); (2) a ketone body or ketone body precursor, such as beta-hydroxybutyrate (BHB) salt, BHB ester, BHB acid, acetoacetate salt, acetoacetate ester, acetoacetic acid, 1,3-butanediol, medium chain fatty acid, or ester of medium chain fatty acid; and (3) optionally a dietetically or pharmaceutically acceptable carrier. The composition may include a vasodilator. The composition may include a short or medium chain fatty acid or ester thereof in addition to or instead of the ketone body or ketone body precursor. The composition can provide enhanced cognitive flexibility, improved sustained attention, improved working memory, and neuroprotection in a mammal. The composition can also beneficially increase resting energy expenditure (resting metabolic rate), particularly when in a state of ketosis, enhancing fat loss principally through ketosis while promoting muscle formation and maintenance, as well as modulating lethargy / lightheadedness when entering a ketogenic state.
Owner:AXCESS GLOBAL SCIENCES LLC

Anti-fatigue beverage containing taurine and preparation method thereof

The preparation method comprises the following steps: respectively pulping and gelatinizing rice and glutinous rice to obtain rice gelatinized liquid and glutinous rice gelatinized liquid, performing enzymolysis on the rice gelatinized liquid through amylase and glucoamylase, performing partial fermentation through lactic acid bacteria, mixing the rice gelatinized liquid with the glutinous rice gelatinized liquid, and performing freeze-drying to obtain the taurine-containing anti-fatigue beverage. The taurine, the inositol, the vitamin B6 and the erythritol are added for blending, and filtering, filling and sterilizing are performed to obtain the product. The prepared anti-fatigue beverage can effectively resist fatigue, has a good taste, does not contain irritant components such as caffeine, and can reduce health risks possibly caused by long-term drinking of functional beverages.
Owner:XIAMEN SHENGYUAN PHARMACEUTICAL CO LTD

Massage cream for promoting blood circulation and removing stasis and preparation method thereof

The invention discloses blood-activating and stasis-removing massage cream and a preparation method thereof, and belongs to the technical field of daily chemical products. According to the massage cream capable of promoting blood circulation and removing stasis, active substances including caffeine, a ginger root extract, heparin sodium, oldenlandia diffusa, a pseudo-ginseng root extract, a carthamus tinctorius TINCTORIUS extract, a palmata pedunculata PALMATA extract and vanillyl butyl ether are added, and after the massage cream is smeared to a body for massage, the effects of moistening skin, removing stasis and promoting blood microcirculation can be achieved, so that the skin is healthier.
Owner:GUANGDONG DESIFU BIOTECHNOLOGY CO LTD