131 results about "Sesamin" patented technology

An orally or parenterally administered composition for reducing the storage of lipids in a human, the composition comprising: an effective amount of hydroxycitric acid; an effective amount of carnitine; an effective amount of biotin; an effective amount of one or more gluconeogenic substrates selected from the group consisting of: aspartate, lactate, glycerol, and a gluconeogenic amino acid or alphaketo analogue thereof; an effective amount of eicosapentanoic acid; and an effective amount of one or more ingredients selected from the group consisting of: medium chain triglycerides (MCT) with fatty acid backbones containing 6 to 14 carbon atoms or their individual fatty acid analogues or metabolic precursors, sesame seeds or derivative products, sesamin and / or its epimer episesamin, caffeine, forskolin, 7-keto dehydroepiandrosterone (7-keto DHEA), green tea extract containing epigallocatechingallate (EGCG), capsaicum, and 5-hydroxytryptophan (5-HTP). The supplement may also be combined with a food, beverage, condiment, spice or salad dressing base to provide a food, beverage, condiment, spice or salad dressing product designed to reduce lipid storage.

The invention discloses a method for extracting sesamin from sesame cake meal, wherein the sesamin is extracted from the raw material of waste sesame cake meal of sesame oil plants. The method comprises the steps of: removing residual oil by utilizing ethanol and ethyl acetate, hydrolyzing protein by utilizing protease, extracting the protein in the hydrolysate by utilizing alkali liquor, and subjecting the oil and protein removed sesame cake meal to supercritical CO2 extraction to obtain the sesamin. The method for extracting the sesamin from the sesame cake meal has the advantages that: physiological active materials such as the sesamin and the like with high additional value are extracted from the waste cake meal left after the sesame oil is extracted from the sesame, therefore, the environmental pollution caused by the waste sesame residue can be reduced and the good economic benefit can be produced so as to drive the further processing study of our country on the sesame, push forward the planting of a characteristic oil crop which is the sesame of our country, promote the structure adjustment of agriculture and increase the income of peasant.

The invention relates to a method for preparing sesamin from seasame cake. It comprises following steps: taking side product sesameseed meal in benne oil factory as raw material, removing left oil using skellysolve B; taking oil-removed seasame cake as raw material, extracting sesamin coarse extract with methanol; separating and purifying with silica gel column chromatography method and getting sesamin. The productivity of sesamin is 1.57%, and purity id 88.02%. The invention makes use of sesameseed meal to prepare seasame that possesses multiple physiologically active substance, so the market prospect is wide.

The invention relates to a method for preparing high-content sesamin from sesame seed meal. The method comprises the following steps: 1) percolating; 2) concentrating the percolate; 3) depigmenting and purifying by use of resin, 4) concentrating the eluate; 5) purifying; 6) crystallizing, namely dissolving the semi-finished sesamin obtained in the step 5) in 10-30 times of 90%-95% ethanol, next, adding a little active carbon, stirring for dissolving for one hour at a temperature within the range of 80-90 DEG C, filtering, cooling the filtrate, crystallizing, filtering, drying the crystals and grinding the crystals to finally obtain the sesamin. The method for preparing the high-content sesamin from the sesame seed meal is used for solving the technical problems of low product content, high production cost, high organic solvent residual and the like of an existing sesamin preparation method, and is high in extraction ratio, and therefore, the cost of the extract is obviously reduced.

The invention provides a preparation process for obtaining high purity sesamin from sesame cake meal. A series of extracting and purifying treatments are carried out on the sesame cake meal by using organic solvents such as normal hexane and the like under a certain condition to obtain the sesamin with high purity finally; raw materials used by the preparation process are solid waste materials of the sesame cake meal which are obtained after preparing sesame oil by squeezing, and the sesamin extracted by separating has higher extraction ratio which reaches about 90%; the obtained sesamin has higher purity which reaches 95.6% by HPLC detection, thereby a good basis for function development and application of the sesamin is established. The invention realizes the comprehensive utilization of the waste materials, greatly increases the additional value of farm products, has very considerable economic benefits, and is suitable for the needs of scale industrial production.

A composition having autonomic nerve function regulating action, comprising sesamin and / or episesamin as an active ingredient, is provided.

The invention discloses a method for extracting sesamin from sesame oil. The sesame oil is used as a raw material. The method comprises the steps of performing primary degassing and primary molecular distillation on the sesame oil, centrifuging and precipitating the distillate to separate the sesamin from the sesame oil, and removing grease from the centrifuged and precipitated distillate through supercritical CO2 extraction to obtain a crude sesamin product; finally, crystallizing the crude sesamin product to obtain a sesamin crystal. By adopting the method disclosed by the invention, high-purity sesamin and high-purity sesame oil can be obtained at the same time, the whole extraction process does not cause any harmful substance pollution, the extraction efficiency is high, and the cost is low.

The invention discloses a method for extracting sesamin from sesame oil root which consists of, extracting reclaimed sesame oil with skellysolve B, using the reclaimed sesame oil as raw material, extracting sesamin crude product by methanol or ethanol,and crystallizing the sesamin crude product.

The invention provides a grease composition containing sesamin. The grease composition comprises a grease matrix and sesamin. The grease composition provided by the invention not only has the health-care function, but also can inhibit the generation of polymers in the frying process.

The invention discloses a method for extracting sesamin from sesame cake meals. The method comprises the following steps: (1) pulverizing and drying the sesame cake meals and then mixing with an organic solvent and leaching the sesame cake meals in a sealed tank to obtain a leach liquid; (2) concentrating the leach liquid to obtain a mixture of sesamin and oil; (3) carrying out molecular distillation on the mixture of sesamin and oil to obtain a light component containing sesamin, cooling the light component and centrifuging to obtain crude sesamin; and (4) crystallizing the crude sesamin to obtain the sesamin. By virtue of the method disclosed by the invention, not only high-purify sesamin but high-quality flour of sesame cake meals can be obtained from the sesame cake meals and the entire extraction process has the advantages of no any pollution caused by harmful substances, high extraction efficiency and low cost.

The invention relates to a making method of an anti-oxidative sausage. A technical scheme adopted in the invention is characterized in that the making method comprises the following steps: stuffing 100 parts of meat, 6-9 parts of white sugar, 2-4 parts of salt, 0.1-0.3 parts of monosodium glutamate, 0.1-0.2 parts of five spice powder, 0.1-0.2 parts of ginger, 1-3 parts of Daqu, 5-15 parts of purified water, and 2-4 parts of sesame powder; rapidly dehydrating a stuffed sausage in a constant-temperature culture box for 2 days; naturally hanging in a shady and ventilated place; and carrying out hanging drying in the sun for 21-30 days, taking down, trimming until orderliness, and carrying out vacuum packaging to obtain the functional sausage. The making method overcomes a defect that many substances harmful to human bodies are generated after the oxidation of fats in present sausages. The anti-oxidative sausage has a better quality and a lower oxidation degree in the production and storage processes than traditional sausages having no additives, and simultaneously has a special functional substance which is sesamin, so the oxidation degree of the sausage in the production and storage processes is reduced to a certain degree, and the healthcare performance of the anti-oxidative sausage is improved.

The present invention relates to a method for providing alpha -glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a alpha -glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said alpha -glucosidase inhibitory agent from the plant source Piper longum in significant yields.

A composition protects against, minimizes the effects of, and hastens recovery from the typical symptoms associated with an alcohol induced hangover. The composition includes superoxide dismutase (SOD), and prickly pear cactus (OFI). In addition, sesamin and alpha-lipoic acid work with the SOD and OFI for enhanced antioxidant and therapeutic effects. Other ingredients can be added to the composition for additional treatment of symptoms.

The invention relates to a composition having effects of whitening, removing spots and refreshing skin. The composition is obtained by uniformly mixing powder of ginkgetin extracted from ginkgo leaves, powder of sesamin extracted from sesame seed meal and powder of astragalosides extracted from radix astragali according to a mass ratio of (1-10): (1-10): (1-10). The composition and make-up preparations or drug excipients can be mixed into an external skin preparation such as cream, an emulsion, gel, paste and a subcutaneous injection. A pharmacological test research shows that the composition has effects of inhibiting skin tyrosinase activity and melanin generation. A clinical trial shows that the composition has obvious whitening, spot-removal and skin-refreshing effects on people having a medium yellow facial color and facial color spots, has an effective rate of 100%, is safe and has no side-effect.

The present invention relates to sesamin concentrating and purifying process. In the process, low concentration sesamin oil is concentrated and extracted with CO2 at the temperature lower than 35 deg.c and in liquid state or gaseous state to obtain high concentration sesamin oil. After low concentration sesamin oil led into the extracting space, CO2 at the temperature lower than 35 deg.c is introduced and most of sesamin flows with CO2, so as to reach the concentration aim.

An adiponectin enhancer comprising as an active ingredient sesamin and / or episesamin, or an analogue thereof.

The invention discloses a composition for protecting lever and achieving a sobering function as well as a preparation method and application of the composition. The composition contains 30-180 parts by weight of sesamin, 1-6 parts by weight of schisandrin B, 150-900 parts by weight of semen hoveniae extract, 150-900 parts by weight of pueraria lobata extract, 0.0012-0.0072 parts by weight of vitamin B12 and 14-84 parts by weight of vitamin E.

The invention relates to a method for preparing sesamin. In the process, sesame is used as a raw material, refluxing extraction in edible ethanol is performed, a solvent is reclaimed under reduced pressure, ammonia water is used for washing, chloroform is added to dissolve the product obtained by washing, the chloroform solution is mixed with 80 to 100-mesh neutral aluminum oxide by stirring, the product obtained after mixing is dried, macroporous resin is added for absorption, No.6 solvent oil and mixed solution of ethyl acetate and methyl alcohol are used for gradient elution, a sesamin fraction is collected, a reagent is recovered till the volume is small, the remaining product is stood for crystallization, refluxing and saturated dissolution is performed in 95 percent ethanol and 70 percent ethanol respectively, and the sesamin product can be obtained by crystallization. The product produced by the method has the advantages of low cost, high yield, high purity and high raw material utilization rate.

The purpose of the present invention is to provide refined sesame oil comprising a lot of lignans that have various excellent physiological properties from sesame seeds having a high lignan content. The present invention relates to refined sesame oil having a sesamin content of 1% by weight or more and showing no bitterness; a method for the production of refined sesame oil comprising using active carbon as an absorbent in a bleaching step; a method for the production of refined sesame oil comprising controlling a bleaching temperature in a range of from 5 to 70° C. in a bleaching step with the use of activated clay active as an absorbent; and a method for the production of refined sesame oil comprising controlling a bleaching temperature in a range of from 5 to 70° C. in a bleaching step with the use of activated clay of from 0.1 to 3% by weight active as an absorbent.

The invention relates to a pure natural complex antioxidant for ganoderma spore oil. The pure natural complex antioxidant is characterized in that the antioxidant with the concentration ratio of 0.08% and a synergist with the concentration ratio of 0.04% are added to the ganoderma spore oil, wherein the concentration ratio is the ratio of the mass of the antioxidant or the synergist to the volume of the ganoderma spore oil, the antioxidant is sesamin, and the synergist is VC (Vitamin C). The pure natural complex antioxidant has the advantages that the pure natural complex antioxidant can be used for maintaining the relatively high activity and stability of the ganoderma spore oil, so that the effect of the ganoderma spore oil is better exerted; the combination of the VC and the sesamin has the synergistic effect, so that the antioxidant resistance of the pure natural complex antioxidant is far higher than that of the VC or the sesamin which is separately used.

The invention provides a nutrition food which contains bran, consisting of stabilized red rice bran, selenium rich red rice powder and black sesame powder, the weight proportion of which are respectively 50 to 60 percent, 10 to 20 percent and 25 to 40 percent. The nutrition food can be prepared by mixing the grinded materials or grinding the mixed materials; the nutrition food which contains the bran has a simple processing method, which reserves all ingredients of the material. The invention utilizes abundant various botanical flavonoids, anthocyanin, organic chromium (trivalence) and magnesium which are especially contained in the red rice bran and rich selenium of red rice; especially high content of organic calcium, especially abundant vitamin E and comparatively abundant sesamin, arachidic acid, sesame polyphenol and phytosterol, etc in the black sesame are utilized to be matched with the existing bran nutrition food, thus making up ingredients insufficiency required by the prevention and cure of diabetes mellitus and angiocardiopathy; the invention becomes a nutrition food which contains bran and is especially applicable to be eaten by diabetes mellitus and angiocardiopathy patients.

Anti-fatigue agents containing dioxabicyclo[3.3.0]octane derivatives such as sesamin which is an ingredient contained in sesame, as well as pharmaceutical compositions and physiologically functional foods that contain such anti-fatigue agents are disclosed. These compounds can safely be administered to humans and animals alike and hence allow for continued ingestion while proving effective in promoting an improvement of stamina, an increase of body strength, a relief of fatigue, and recovery from fatigue.

The invention discloses sesame oil with a whitening effect. The sesame oil is prepared from the following raw materials in parts by weight: 1100 to 1200 parts of white sesame seed, 60 to 70 parts of coix seed, 10 to 15 parts of sweet-scented osmanthus, 5 to 10 parts of dried small shrimps, 5 to 8 parts of peony seed kernel, 10 to 15 parts of almond, 20 to 25 parts of white radish, 15 to 20 parts of pear, 20 to 30 parts of lemon, 30 to 40 parts of wax gourd, 2 to 3 parts of bighead atractylodes rhizome, 4 to 5 parts of radix paeoniae alba, 4 to 5 parts of white poria, 5 to 8 parts of milk, and proper amount of edible alcohol and water. According to the sesame oil with the whitening effect, the white sesame seed is used as the main raw material; coix seed has the effects of invigorating spleen to remove dampness, clearing away heat and eliminating pus, and whitening and beautifying; the added bighead atractylodes rhizome, radix paeoniae alba and white poria are traditional combination drugs capable of moistening the skin and whitening and have good effects on tonifying Qi and nourishing blood, whitening and moisturizing the skin; sesamin in the prepared sesame oil is rich in content and has an obvious flavor, and thus the nutritional value of the sesame oil is increased.

The invention discloses mung bean and rhizoma dioscoreae chewable tablets which comprise the following components in parts by weight: 2-8 parts of rhizoma dioscoreae, 2-8 parts of mung bean, 0.01-0.05 part of sesamin, 12-16 parts of sorghum flour, 4-8 parts of soybean extract, 0.3-0.7 part of casein phosphopeptides, 0.01-0.03 part of calcium gluconate, 1-3 parts of microcrystalline cellulose, 0.3-0.7 part of apple cellulose, 0.01-0.03 part of vitamin C, 0.01-0.03 part of xylitol, 0.01-0.03 part of sorbitol and 0.02-0.04 part of magnesium stearate. The mung bean and rhizoma dioscoreae chewable tablets disclosed by the invention have the functions of clearing summer heat, improving bone density, enhancing immunity and supplementing vitamin C, are suitable for summer and have pure taste.

The invention discloses a method for extracting sesamin from sesame seed husks. The method comprises the following steps: by adopting by-products, namely sesame seed husks obtained after sesame peeling as raw materials, firstly extracting the sesame seed husks with an organic solvent, and then adopting a low-temperature crystallization method after concentrating the extracting solution, thus obtaining high-purity sesamin. The purity of sesamin obtained by the method can reach 95%, so that the method is obviously better than existing methods. Meanwhile, the method avoids pollution caused by any harmful substance, has the characteristics of simplicity in operation, stable process, low extraction cost, high economic benefits and the like, and can be used for industrially extracting sesamin in a large scale.

Belonging to the technical field of plant detection, the invention specifically relates to a method for determining the content of sesamin in sesame. The method includes the steps of: (1) drawing a standard work curve at a 287nm wavelength site; (2) crushing a sesame sample and then conducting specific treatment; (3) performing HPLC determination on the sample, and carrying out lookup or calculation according to the prepared standard work curve, thus obtaining the content of sesamin in the sesame sample. The determination method provided by the invention is simple, fast and efficient, has high sensitivity, can maximumly extract sesamin in the sample to conduct determination so as to be closer to a true value, and can be carried out on a large scale.

The invention relates to a preparation method for water-soluble seamin. The preparation method comprises the following steps: selecting sesame seed meal as a raw material; performing secondary enzymatic hydrolysis, water washing, solvent extraction, active carbon treatment, cyclodextrin inclusion, membrane separation and freeze drying technology to obtain a water-soluble sesamin product of which the sesamin content is not lower than 65 percent by weight and the sesamin recovery rate is higher than 95 percent. The method is simple and convenient in steps; moreover, the conventional method using a toxic reagent, namely, diethyl ether or n-hexane is abandoned, so that the finished product quality of the sesamin product is ensured well, the water-soluble sesamin product is obtained directly, and subsequent production and utilization of the sesamin product are facilitated well.

A pharmaceutical composition, including, parts by weight of: 100-170 of a ginkgo flavone, 40-100 of a jujube extract, 100-200 of an extract of a peel of Trichosanthes kirilowii, 30-60 of a saponin of Codonopsis, 50-100 of a saponin of American ginseng, 40-70 of a saponin of Radix astragalu, 20-50 of hirudin, 3-10 of a coenzyme Q10, 40-100 of a longan extract, 20-50 of a modified starch, 100-150 of a carthamin, 100-150 of an extract of peach kernel, 30-50 of a gastordin, 120-200 of a salvianolic acid, 40-90 of an extract of Ligusticum chuanxiong, 100-150 of a saponin of Panax notoginseng, 0-50 of a black sesamin, and 0-50 of an astaxanthin.

The present application relates to a method for extracting sesamin, which is characterized in that it comprises: soaking crushed sesame in an extraction tank containing an extractant for a predetermined time; extracting sesame in the extraction tank to obtain an extract containing sesamin liquid; use a three-effect concentrator to concentrate the extract to obtain a concentrated solution containing sesamin; add the concentrated solution to a crystallization tank for crystallization to obtain sesamin crystals; add the sesamin crystals to a refining tank and add ethanol for Decolorizing and refining to obtain the finished product of sesamin. Using the extraction method of the scheme of the present application improves the purity of sesamin, reduces production energy consumption and production cost.