8 results about "Sesamin" patented technology

The application discloses a composition containing sesame lignan compounds and application thereof, and selects at least one of sesame lignan or similar compounds, glycoside compounds as a main active ingredient, so that the obtained composition can significantly improve physiological activities in the aspects of controlling fat in vivo, regulating intestinal flora, maintaining blood fat, blood sugar, blood pressure, protecting liver, controlling appetite, antioxidation and anti-aging, etc. Compared with single components, two or more than two compound combinations have a better synergistic effect. Meanwhile, the components in the composition are pure natural plant food raw materials, and have no toxic side effects. Therefore, the composition has a good application prospect.

The invention belongs to the technical field of active component and target screening, and relates to a purple sweet potato leaf uric acid reducing active component and a potential target and a screening method thereof, the active component comprises rhododendron yellow, 3, 4, 2 ', 4', 6 '-pentahydroxychalcone, apigenin, quercetin glycoside, 6-hydroxycoumarin, 6, 6-dihydroxycoumarin, 3, 4, 2', 4 ', 6'-pentahydroxychalcone, 3, 4, 2 ', 4', 6 '-pentahydroxychalcone, 3, 4, 2', 4 '-pentahydroxychalcone, the component A is prepared from 2, 7-dihydroxy coumarin, daphnetin, trigonelline, serotonin, salidroside, sesamin and nicotinamide; the potential target spots comprise INS, PPAR-gamma, IL1-beta, PPAR-alpha, XDH and ABCG2; the method comprises the following steps: preparing purple sweet potato leaves and a sweet potato leaf water extract, determining the uric acid generation inhibition activity of the purple sweet potato leaves through an in-vitro experiment, and carrying out differential metabonomics combined network pharmacology analysis to excavate functional substances for reducing uric acid in the purple sweet potato leaves, thereby providing a material basis for high-valued utilization of the purple sweet potato leaves and development of functional foods for reducing uric acid.

The invention discloses a method and system for detecting adulteration in vegetable fat and application, the method comprises the following steps: step 1, pre-treating a sample, specifically comprising the following steps: step 11, weighing the sample, adding methanol for vortex oscillation and ultrasonic extraction, centrifuging, and taking supernate; step 12, adding a C18 adsorbent into the supernate obtained in the step 11 for purification, and filtering to obtain a test solution; step 2, analyzing the test solution by using ultra-high performance liquid chromatography in series with triple quadrupole mass spectrometry UPLC-MS / MS (Ultra Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry); 3, whether the target vegetable fat is doped into the sample or not is judged on the basis of the detection result of the characteristic markers, and the characteristic markers comprise sesamin and sesamolin in sesame oil, 4 ', 7-dimethoxy-isoflavone 4', 7-Dimethoxyisoflavone in soybean oil and Sativanone in peanut oil. The invention aims to improve the high sensitivity and high specificity for detecting adulteration in vegetable fat.

This invention belongs to the field of plant protein processing technology, and relates to a method for modifying sesame protein based on endogenous polyphenols and its application. Using cold-pressed sesame cake as raw material, after defatting and pulverizing pretreatment, sesame protein is extracted using an alkali-dissolution-acid precipitation method. The extraction time, temperature, material-to-liquid ratio, and pH are optimized using single-factor experiments and response surface methodology to induce non-covalent and covalent interactions between sesame endogenous polyphenols and protein, constructing a stable protein-polyphenol complex system. Under optimized conditions, sesamin and sesamin can efficiently bind to protein, resulting in a polyphenol content of 40-55 mg / 100 g, a protein purity of not less than 80%, and an extraction rate of not less than 35% in the modified sesame protein. Compared with dephenolized sesame protein, its molecular structure undergoes certain changes, and its solubility, emulsifying properties, and antioxidant properties are significantly improved. Specifically, the solubility is not less than 40%, the emulsifying activity is 25-45 m² / g, the emulsifying stability is 60%-85%, and it exhibits good scavenging ability against DPPH and ABTS free radicals, while also demonstrating superior colloidal stability and interfacial characteristics. This invention eliminates the need for exogenous polyphenol addition, employs a green and efficient process, and yields modified sesame protein that can be used as a functional ingredient in highly stable emulsions, functional foods, and active substance delivery systems, thereby enhancing system stability and antioxidant properties.

The invention discloses a preparation method and application of sesamin targeted carrying nanoparticles, and the preparation method comprises the following steps: reacting ketal thiol TK, 2-succinimido-1, 1, 3, 3-tetramethylurea tetrafluoroborate, N, N-diisopropylethylamine and iramitide SS-31 peptide to prepare an SS31 peptide-TK compound, then reacting with chitosan, and simultaneously preparing a sodium alginate-lactobionic acid compound, so as to obtain the sesamin targeted carrying nanoparticles. Finally, mixing the two solutions to obtain a covalent complex; the method comprises the following steps: baking pork slices, extracting with ethanol, filtering, carrying out rotary evaporation, extracting, dialyzing and purifying, and freeze-drying; and mixing the products of the first two steps, dissolving in ethanol, adding sesamin, and carrying out electrostatic self-assembly and freeze drying to obtain the visual sesamin targeted nanoparticles. According to the invention, specific positioning of liver mitochondria, ROS stimulation response intelligent drug release and real-time visualization of food-borne fluorescence labeling are realized, and the application prospect in prevention and treatment of liver diseases is wide.

The invention relates to sesame paste prepared by a mid-infrared roasting-grinding coupling technology as well as a preparation method and application of the sesame paste, and belongs to the technical field of foods. The invention provides sesame paste, and in the particle size distribution of the sesame paste, the D10 value is 1.83 to 8.28 [mu] m, the D50 value is 73.22 to 154.95 [mu] m, and the D90 value is 251.97 to 341.84 [mu] m. The conversion efficiency of sesamolin to sesamol is remarkably improved through infrared roasting, and under the synergistic effect of moderate grinding and infrared roasting, phenolic substances in cells are effectively released and excessive oxidative degradation is avoided, so that the total phenol content and the sesamol content are improved, the antioxidant activity and oxidation stability of the sesame paste are remarkably improved, and the nutritional value of the sesame paste is improved. The shelf life is prolonged.

The invention discloses a preparation method of sesamin oil loaded gel with high stability and high bioavailability. According to the oleogel, vegetable protein, vegetable oil and water are taken as main raw materials, and uniform dispersion and self-assembly structuring of the vegetable protein in an oil phase are realized through a mechanical energy auxiliary mixing treatment process under the condition that no gelling agent is added, so that a stable three-dimensional oleogel network is constructed. The lipophilic active component sesamin is effectively loaded by the system, so that embedding and stabilization of the sesamin are realized, and the stability and bioavailability of the sesamin in a gastrointestinal environment are remarkably improved. The obtained oleogel has excellent structural stability, relatively high storage modulus and extremely high oil holdup. The method is simple and convenient in process, green and safe, free of organic solvent residues, capable of achieving large-scale production and suitable for development and application of functional food, nutritional supplements and drug delivery systems.

This invention discloses compositions containing sesamol compounds and their applications. The compositions include at least two of sesamol, sesamol dimer, and sesamin glucoside. This invention uses specific compounds from sesamol and its analogues, derivatives, and metabolites as the main active ingredients, resulting in compositions that exhibit synergistic effects, significantly enhancing physiological activities such as controlling body fat, regulating intestinal flora, maintaining blood lipids / blood sugar / blood pressure, protecting the liver, controlling appetite, anti-oxidation, and anti-aging. Furthermore, all components in this composition are derived from pure natural plant-based foods, with no toxic side effects; and the preparation method is simple and easy to operate, making it suitable for preparing related health foods, pharmaceuticals, feed, and feed additives, with promising application prospects.