3222 results about "Fatty acid" patented technology

The invention discloses a method for improving beef quality, an action mechanism and an experimental method, in a cattle body, vitamin A can activate the expression of EBF2 through an active metabolite RA of the vitamin A, and the EBF2 can inhibit the transcription process of CYP26B1 in a targeted manner to maintain the activity of a retinol signal channel, so that PPAR gamma and downstream lipid metabolism related genes thereof are activated, and the activity of the retinol signal channel is improved. Fatty acid transport and lipid accumulation in fat cells in the cattle muscle are promoted, fat deposition in the cattle muscle is promoted, and the beef quality is improved. By constructing the molecular network for regulating and controlling the formation of the fat in the cattle muscle, a complex regulation and control mechanism for controlling the fat deposition in the cattle muscle can be understood more deeply, a method for improving the beef quality based on regulating and controlling the vitamin A mediated key factor EBF2 is provided, and a new way is provided for improving the beef quality in a targeted manner.

A process is provided for upgrading low value lipid feedstocks for refinery processing. The process includes (a) treating a lipid feedstock comprising at least one fatty acid with a metal oxide catalyst on an oxide support under treating conditions to produce a treated stream, wherein the treating conditions include a temperature in a range of from 400° C. to 700° C.; a pressure in a range of from 0 to 10 MPa; and a liquid hourly space velocity in a range of from 0.1 to 10 h−1; and (b) fractionating the treated stream to obtain a gaseous fraction and a liquid fraction comprising a bio-oil; wherein the bio-oil has a lower content of oxygen and impurities as compared to the lipid feedstock.

The invention relates to the technical field of microorganisms, in particular to a culture medium and a method for culturing Ackermania muciniphila for activating Amuc-1260 by using lambda-carrageenan as a carbon source, according to the culture method, the lambda-carrageenan is used for replacing a traditional carbon source, thallus growth and proliferation can be remarkably promoted, the effect is optimal under the condition of 2.00 g / L, and the culture cost is low. Compared with the conventional carbon source (glucose), the carbon source is improved by 92.91%. Further research finds that the lambda-carrageenan can induce the Akk bacteria to up-regulate the expression of glycoside hydrolase such as Amuc-1260 and enhance the activity of pathways such as glycosaminoglycan degradation, amino acid metabolism and insulin signals, so that the metabolic adaptability and energy utilization efficiency of the bacteria are improved. Meanwhile, the Akk bacteria secrete more functional short-chain fatty acids such as acetic acid, propionic acid and the like under the condition, and have the effects of regulating intestinal health and maintaining metabolic homeostasis. The invention provides a new theoretical basis and technical support for large-scale culture of Akk bacteria and development of a metabiotic product.

The invention relates to a bifidobacterium animalis subsp. Lactis B7 as well as a composition and application thereof, and belongs to the technical field of microorganisms, the bifidobacterium animalis subsp. Lactis B7 is preserved in the China Center for Type Culture Collection on April 19, 2024, and the preservation number is CCTCC NO: M2024734. The bifidobacterium animalis subsp. Lactis B7 is named as Bifidobacterium animalis subsp. Lactis B7, the composition is named as Bifidobacterium animalis subsp. Lactis B7, and the composition is named as Bifidobacterium animalis subsp. Lactis B7. The invention also discloses application of the B7 fermentation composition in preparation of medicines for preventing and treating ulcerative colitis, constipation and constipation-type ulcerative colitis. According to the bifidobacterium animalis subsp. Lactis B7, high-yield short-chain fatty acid and indolepropionic acid are achieved, sulforaphane is generated through glucoraphanin, intestinal tract movement is improved, ulcerative colitis or inflammatory bowel disease activity index DAI and weight loss caused by the disease activity index DAI are effectively relieved, mouse colon injury is remarkably relieved, and mucosa layers are protected; the effects of resisting inflammation, inhibiting pathogenic bacteria and improving the intestinal barrier function are achieved.

A corrosion inhibitor composition includes a fatty acid ethoxylate, a thiourea, an arylthiourea, a thiazole, and two or more solvents. A metal article in contact with the composition has a corrosion rate of about 25 to about 45 mils penetration per year (mpy), as determined by an ASTM G111 standard test method. A method for inhibiting corrosion of a metal in contact with a corrosive fluid.

The invention relates to the technical field of cosmetics, and discloses an anti-inflammatory soothing cosmetic composition which comprises the following components in percentage by weight: 0.5%-4% of a barrier repairing component, 0.5%-3% of an immunoregulation component, 0.3%-2.5% of a nerve soothing component, 0.3%-3% of an anti-inflammatory plant compound, 1%-10% of a moisturizing soothing enhancer and the balance of auxiliary materials. According to the components, through a five-dimensional synergistic mechanism of barrier repair, immune tolerance, nerve desensitization, anti-inflammatory itching relieving, moisturizing and stability maintaining, anti-inflammatory relieving and barrier repair are remarkably enhanced; ceramide, rare ginsenoside, phytosterol ester and free fatty acid are introduced to synergistically construct a bionic liposome which is closer to the composition of human cuticle lipid, so that the transdermal absorption and stability are enhanced, and the repair efficiency is remarkably improved; the dipotassium glycyrrhizinate, the tamarix chinensis flower extract, the purslane extract, the dinoflaxanthine and the baicalin cooperate to quickly resist inflammation and relieve itching and strengthen barrier repair, so that the composition is suitable for highly sensitive skin.

The invention relates to a diacylglycerol acyltransferase mutant and application thereof in synthesis of triacylglycerol from saccharomyces cerevisiae, and belongs to the technical field of enzyme engineering. Diacylglycerol acyltransferase is a rate-limiting step of a synthetic route of saccharomyces cerevisiae triacylglycerol (TAG), and at present, a research on a DGA1 mutant for efficiently synthesizing TAG is lacked, and a research on the aspect of a DGA1 catalytic mechanism is also lacked. The DGA1 mutant capable of effectively improving TAG synthesis is obtained by screening in combination with a directed evolution technology, and a result shows that 282-site mutation of diacylglycerol acyltransferase can significantly increase the accumulation amount of TAG. Meanwhile, the catalytic mechanism of the DGA1 is preliminarily explored by combining protein structure prediction, molecular docking and molecular dynamics simulation, and a foundation is laid for deeply analyzing the catalytic mechanism of the DGA1. The recombinant saccharomyces cerevisiae is also constructed based on the mutant, so that the TAG synthesis is improved, and meanwhile, the relative proportion of C18: 1 in total fatty acids is remarkably increased.

The invention provides a cyclic peptide as well as a preparation method and application thereof. The cyclic peptide has an amino acid sequence # imgabs0 # represented by formula (1) (wherein X is a Lys residue modified with a fatty acid molecule, and a line connecting Arg and Lys represents an amide bond. The cyclic peptide prepared by the invention has wide antifungal activity and antibacterial activity on drug-resistant bacteria; meanwhile, the biotoxicity and the protease degradation resistance are high, and the in-vivo antibacterial effect of the cyclopeptide can be prolonged. The cyclic peptide can be applied to preparation of anti-bacterial and anti-fungal infection drugs, and can be used as an excellent substitute drug or an auxiliary drug of existing antibiotics. The method for preparing the cyclic peptide is simple, raw materials are easy to obtain, and industrial production can be achieved.

The application discloses a specific palmitoyl transferase inhibitor and application thereof, and an active ingredient of the palmitoyl transferase inhibitor is 4-(3-(2-(trifluoromethyl)-9H-thioxanthene-9-ylidene)propyl)-1-piperazine ethanol or a salt thereof. Current palmitoylation inhibitors, 2-bromohexadecanoic acid (2-BP), cerulenin and tunicamycin can all inhibit protein palmitoylation in cells, but all are not selective. And the existing palmitoylation inhibitors are similar to endogenous fatty acids, and inevitably affect lipid metabolism in the body, which limits the clinical application. The application discloses, for the first time, the application of 4-(3-(2-(trifluoromethyl)-9H-thioxanthene-9-ylidene)propyl)-1-piperazine ethanol as a specific palmitoyl transferase inhibitor, and the palmitoyl transferase inhibitor is better in specificity and reversible in inhibition.

The invention discloses a method for evaluating piglet feed digestibility based on excrement indexes, and particularly relates to the field of piglet feed digestibility evaluation.The method comprises the steps that a piglet excrement sample under target feed intervention is obtained, and multiple biochemical index data in a preset time sequence are collected for the excrement sample; the biochemical index data comprises moisture content, ammonia nitrogen concentration and short-chain fatty acid concentration, and a corresponding excrement index original data sequence is formed according to the biochemical index data. Continuous aggregation of discontinuous sampling data is realized by constructing a sample index structure, and in combination with frequency domain feature extraction, interpolation reconstruction and a collaborative tensor modeling mechanism, an absorptivity inversion path having a robust adaptability to missing and asynchronous data is established. The key problems that in the prior art, a current evaluation method seriously depends on data integrity, and discontinuous information in a real sampling environment cannot be processed are solved.

The invention provides transparent shampoo with fluffy and anti-dandruff effects and a preparation method of the transparent shampoo. The shampoo comprises the following components in percentage by weight: 10%-20% of sodium laureth sulfate; 0.5% to 10% of ammonium laureth sulfate; 0.5%-10% of cocamidopropyl betaine, 0.5%-10% of 0.5%-10% of coconut oil fatty acid monoethanolamide; 0.5% to 10% of decyl glucoside; 0.6% to 1.5% of capryloyl glycine; 0.1% to 1% of cationic guar gum; 0.1% to 1% of polyquaternium-10; 0.1% to 1% of polyquaternium-11; 0.1% to 1% of polyquaternium-51; 0.01% to 2% of magnolol; 0.01% to 2% of menthol; 0.1%-1% of sodium chloride; 0.1%-1% of citric acid; and 0.1%-1% of disodium EDTA. The shampoo disclosed by the invention has the effect of improving the combing performance in a dry hair state, can effectively improve the smoothness of hair and the touch comfort during use, and also has a supporting effect and antibacterial and anti-dandruff effects. According to the shampoo process, the clarity and appearance stability of the product are remarkably improved, and the shampoo can be kept in a transparent and uniform state for a long time.

The invention discloses a method for comprehensively recovering lithium beryllium resources in spodumene tailings, and belongs to the technical field of mineral separation. The method comprises the steps that after spodumene tailings are subjected to size mixing, amine and fatty acid serve as a combined collecting agent, flotation I is conducted, and mica concentrate and tailings I are obtained; after size mixing is conducted on the tailings I, sodium sulfide and phosphate serve as a combined inhibitor, a metal-hydroximic acid organic complex and fatty acid serve as a combined collecting agent, flotation II is conducted, and lithium beryllium bulk concentrate and tailings II are obtained; and after size mixing is conducted on the lithium beryllium bulk concentrate, flotation III is conducted with phosphate and EDTA as a combined inhibitor and fatty acid as a collecting agent, and beryllium concentrate and lithium-containing tailings are obtained. By means of the method, the beryllium concentrate with the BeO grade being 4.448% and the recovery rate being 64% can be obtained, meanwhile, the lithium concentrate with the Li2O grade being 4.8% and the recovery rate being 57.6% can be produced, deep comprehensive recovery of the lithium beryllium resources in the spodumene tailings is effectively achieved, and the economic benefit capacity is large.

The invention discloses a mineral oil defoaming agent for water-based paint ink and a preparation method of the mineral oil defoaming agent, and belongs to the technical field of defoaming agents. A hydroxyl-terminated butenyl polymer and hydrogen-containing silicone oil are used for preparing a modified butenyl polymer under the condition of a platinum catalyst; and preparing the mineral oil defoaming agent from the obtained modified butenyl polymer, mineral oil, white carbon black, fatty acid metal soap and wax under the action of an emulsifier. The mineral oil defoaming agent prepared by the invention not only has the advantage of high defoaming speed of a conventional mineral oil defoaming agent, but also has improved compatibility and stability, is a defoaming agent with strong defoaming ability, good foam inhibition performance, good compatibility with paint and ink and reduced coating shrinkage phenomenon, and has good application prospects in the fields of paint and ink. The method has a wide application prospect especially in the field of home decoration water-based paint ink.

The invention relates to a composite hydroxypropyl methylcellulose skeleton sustained-release material and a preparation method thereof, and belongs to the technical field of drug sustained release. The sustained-release material is prepared from 70 to 90 parts of hydroxypropyl methylcellulose (HPMC), 10 to 20 parts of sodium alginate, 8 to 15 parts of chitosan, 0.1 to 0.2 part of Omega-3 fatty acid, 0.05 to 0.06 part of vitamin D, 2.5 to 5 parts of soluble calcium salt-zinc salt composite cross-linking agent, 0.5 to 1.5 parts of hydrolyzable cross-linking agent, 3 to 10 parts of enzyme sensitive auxiliary material, 1 to 5 parts of pore-foaming agent and 2 to 8 parts of hydrophobic blocking agent. The preparation method comprises the steps of raw material pretreatment and dry mixing, active component dispersion liquid preparation, wet granulation and primary cross-linking, secondary cross-linking and drying, vacuum drying and size stabilization, curing and packaging and the like. The sustained-release material provided by the invention has the advantages of controllable drug release rate, good mechanical strength and biodegradability, is suitable for sustained-release delivery of Omega-3 fatty acid, vitamin D and other active components, and can improve the bioavailability and stability of drugs.

The invention relates to the technical field of functional lipid preparation, in particular to high-purity nannochloropsis oculata polar lipid enriched by an enzymic method and a preparation method of the high-purity nannochloropsis oculata polar lipid. The method comprises the following steps: specifically and selectively hydrolyzing triglyceride by using immobilized Lip2 lipase to generate glycerol and free fatty acid, retaining and enriching polar lipid components, and carrying out centrifugal filtration and molecular distillation to obtain the high-purity nannochloropsis oculata polar lipid. The invention provides a method for preparing high-purity polar lipid by performing enzymolysis on nannochloropsis oculata oil by using lipase Lip2 produced by yarrowia lipolytica, which maximally retains the polar lipid and obtains a high-purity polar lipid product through the specific catalytic action of Lip2 lipase. The method which is mild in reaction condition, environment-friendly, simple in step and high in purity is provided for efficient enrichment of the nannochloropsis oculata polar lipid, the prepared polar lipid product is extremely high in purity, and the blank of efficient preparation of the nannochloropsis oculata polar lipid in the prior art is filled.

The invention relates to the technical field of metal working fluids, in particular to a degradable environment-friendly vegetable oil-based semi-synthetic cutting fluid and a preparation method thereof. The cutting fluid comprises 20-30 parts of vegetable lubricating oil, 10-20 parts of an alkali storage agent, 2-5 parts of a corrosion inhibitor, 3-5 parts of a coupling agent, 5-8 parts of a surfactant and 6-11 parts of a composite anti-rust agent, the composite anti-rust agent comprises an anti-rust agent A and an anti-rust agent B, the anti-rust agent A comprises N-[3-(dimethylamino) propyl]-N, N-dimethylformamide, and the anti-rust agent B comprises N-[3-(dimethylamino) propyl]-N, N-dimethylformamide. The antirust agent A comprises at least one of N, N ', N'-trimethyl-1, 3-propanediamine, benzotriazole, sebacic acid and 2, 4, 6-tri (aminocaproic acid)-1, 3, 5-triazine, and the antirust agent B comprises at least one of an imidazoline compound and fatty acid sarcosine ester. The cutting fluid provided by the invention has excellent corrosion resistance, rust resistance, defoaming property, biodegradability and storage stability, and has a good application prospect.

The invention provides an insecticidal pesticide synergistic additive containing plant essential oil and a preparation method thereof, and belongs to the technical field of pesticide synergists. The insecticidal pesticide synergistic aid containing the plant essential oil comprises a synergist matrix, a penetrating agent, an emulsifying agent, a thickening agent, an anti-freezing agent and the plant essential oil. The main component of the synergistic additive is esterified vegetable oil or fatty acid alkyl ester, and the synergistic additive has the advantages of low toxicity, difficult generation of drug resistance of target organisms, environmental friendliness and the like, and can be mixed with a penetrant, an emulsifier and a thickener for use, so that the wetting and infiltration capacity of pesticide liquid can be remarkably enhanced, a wax layer structure can be destroyed, the permeability of the pesticide liquid can be improved, and the pesticide effect can be improved. The added plant essential oil belongs to a natural active substance, has the characteristics of being green and environment-friendly, and can be matched with different pesticide formulations such as insecticides, bactericides, herbicides and the like for use.

Disclosed herein are improved walnut tissues and embryos, methods of obtaining fatty acid compounds from walnut tissues, methods of cultivating walnut tissues, and fatty acid compounds.

The invention discloses a compound probiotic for improving cognitive function of old people and a preparation method and application thereof. Firstly, maltodextrin is dried and then sieved, metal impurities are removed after sieving, and maltodextrin freeze-dried powder, lactobacillus paracasei Lpc37 freeze-dried powder, phytobacterium plantarum Lp-115 freeze-dried powder and bifidobacterium animalis subsp. Lactis Bl-04 freeze-dried powder are weighed and sieved respectively; the preparation method comprises the following steps: preparing freeze-dried powder of three strains, then premixing the freeze-dried powder of the three strains with a part of maltodextrin, adding the residual maltodextrin after the strains are premixed, continuously mixing until the materials are uniformly distributed to obtain the compound probiotics, exerting a synergistic effect through a specific strain combination (Lp115 + Lpc37 + Bl-04), providing a new way for non-drug intervention, being beneficial to regulating intestinal flora metabolism (such as generating short-chain fatty acid SCFA), and improving the immunity of the human body. The synthesis and release of neurotrophic factors are promoted, the nerve cell function is improved, and the cognitive function improvement is indirectly assisted.

The invention belongs to the field of material surface treatment, and relates to a glass explosion-proof rubber coating process. According to the process, alpha-Al2O3 nanoparticles and fatty acid grafted modified nano SiO2 are prepared, a nano composite adhesive containing aramid fibers and nickel hydroxyl iron powder is prepared in combination with a three-stage dispersion process (mechanical shearing, ultrasonic cavitation and rolling grinding), and a glass surface nano rough interface is constructed in combination with plasma treatment and a PECVD (Plasma Enhanced Chemical Vapor Deposition) technology. A magnetoelectric synergistic coating (magnetic field orientation + vacuum infiltration + gradient pressure + electrostatic overlock) and electromagnetic curing-gradient cooling process is adopted to realize uniform coating and rapid crosslinking of an adhesive layer. Through cooperation of material modification and a multi-field coupling process, the impact energy absorption of an adhesive layer is greater than or equal to 80%, the interface bonding strength reaches 22MPa, the curing time is shortened by 50%, degumming is avoided in an extreme environment, and the thickness deviation of the adhesive layer is + / -5 [mu] m. By adopting natural raw materials and a low-VOC formula, the anti-explosion glass is suitable for scenes such as building curtain walls and automobile glass, the anti-explosion performance is improved, and the service life is prolonged.

The invention discloses a method for extracting eucommia ulmoides with an intestinal repair function, and relates to the technical field of natural product extraction.The method comprises the steps that a fresh eucommia ulmoides raw material is subjected to low-temperature drying and smashing, a polysaccharide water extract and filter residues are obtained through water extraction, and then the flavone residual quantity in the polysaccharide water extract is synchronously detected; carrying out enzymolysis on the polysaccharide water extract through beta-glucanase to obtain a small molecular polysaccharide solution, and carrying out alcohol extraction on filter residues to obtain a flavone alcohol extract; the preparation method comprises the following steps: mixing the two components according to a ratio, inoculating compound probiotics for anaerobic fermentation, regulating according to the residual quantity of flavone, regulating an alcohol extraction process by using short-chain fatty acid generated by fermentation when the residual quantity is high, supplementing flavone extract in an enzymolysis system when the residual quantity is low, and finally removing impurities, purifying, adapting intestinal tracts and drying to obtain the product. According to the method, regulation and control operation is correspondingly executed by detecting the residual quantity of flavone in the polysaccharide water extract, so that self-supply of a regulation and control reagent and high efficiency of active ingredients are realized, the conversion rate of small molecular polysaccharide and flavone aglycone is increased, and the intestinal tract tolerance of the product is optimized.

The invention relates to polyethylene glycol glycerol ricinoleate granules as well as a preparation method and application thereof. The granules comprise first polyethylene glycol glycerol ricinoleate with an HLB (Hydrophile-Lipophile Balance) value of 17-19, second polyethylene glycol glycerol ricinoleate with an HLB value of 12-14, a carrier and vitamin E acetate. According to the invention, fatty acid and / or hydrogenated vegetable oil are / is taken as a nutritional carrier, and polyethylene glycol glycerol ricinoleate with an HLB value of 12-14 is introduced, so that the dispersity of active ingredients with a high HLB value (17-19) in the carrier is effectively improved, and granulation is facilitated; meanwhile, the vitamin E acetate is added, so that the immunity of animals can be enhanced while the effects of resisting oxidation and prolonging the shelf life of the product are achieved. The granules solve the problems that pure products are not easy to mix, inconvenient to use and the like.

The invention discloses an application of pleurotus eryngii purified polysaccharide in preparation of an intestinal care medicine. The pleurotus eryngii purified polysaccharide component has high immunocompetence, high-activity and high-purity polysaccharide is obtained after ethanol precipitation and organic solvent purification, and the high biological activity of the polysaccharide is reserved; the composition has the biological activity of increasing the production of short-chain fatty acid, reducing the inflammation level, improving the intestinal flora structure, influencing the body metabolism condition and protecting the intestinal barrier. Compared with other components in the pleurotus eryngii polysaccharide extraction process, the polysaccharide component obtained by the preparation method has the highest purity and the strongest biological activity, and can be used for preparing intestinal care medicines.

The invention discloses a method and a system for efficiently producing short-chain fatty acid by utilizing waste molasses in the sugar industry and municipal sludge through synergistic anaerobic fermentation, and belongs to the technical field of organic solid waste recycling. Waste molasses and municipal sludge are mixed according to a specific ratio, the carbon-nitrogen ratio is optimized to 20-30: 1, trace metal catalysts (Fe < 2 + >, Co < 2 + > and Ni < 2 + >) are added, and two-stage pH regulation (the initial pH is 6.0-7.0, and the later pH is 5.5-6.0) and a medium-temperature (35-37 DEG C) anaerobic fermentation process are combined, so that the yield of short-chain fatty acid is remarkably increased to 5.2-6.8 g COD / L and is increased by 200-300% compared with that of traditional sludge single-substrate fermentation. The method realizes recycling and high-value conversion of the organic solid waste, and has the characteristics of low cost, high acid production efficiency and environmental friendliness.

The invention relates to high-adhesion weather-resistant water-based ink and a preparation process thereof, and relates to the field of ink materials and preparation, and the high-adhesion weather-resistant water-based ink is prepared from the following raw materials in parts by mass: 25-40 parts of waterborne polyurethane, 10-20 parts of waterborne acrylate, 35-50 parts of water-based color paste, 1-4 parts of auxiliaries and water; the water-based acrylate is obtained through emulsion polymerization, and polymeric monomers comprise epoxy acrylate, hydroxyethyl acrylate, pentaerythritol tetraacrylate and acrylic acid; the epoxy acrylate comprises fatty acid modified epoxy diacrylate. The preparation method comprises the following steps: adding the water-based polyurethane resin and the water-based acrylate into water, stirring, adding the water-based color paste, stirring, adding the auxiliary agent, stirring, adjusting the viscosity, stirring, and filtering to obtain the high-adhesion weather-resistant water-based ink. The water-based ink has the effect of improving the adhesive force and weather resistance of the water-based ink.

The application relates to the technical field of oil refining, in particular to a processing device for removing cyclopropene fatty acids in cottonseed oil, which comprises a shell and a shell cover, the shell cover is fixedly installed on the top of the shell, a mixing assembly is movably installed in the shell, the mixing assembly comprises a screening frame, a sliding plate and two connecting pipes, one end of the connecting pipe is fixedly connected with the bottom of the shell and communicates with the bottom of the shell. The mixing liquid is sprayed through the corresponding nozzles, so that the mixing liquid collides with each other to be refined, the mixing efficiency of the mixing liquid is improved, the mixing liquid is separated through the sliding plate and the screening frame, the screening frame scrapes off and screens the soap nuts and impurities in the mixing liquid, the sliding plate pushes the mixing liquid upwards, the mixing effect of the mixing liquid is improved, the air in the shell is extruded, so that the air cleans the soap nuts and impurities in the connecting pipe, the diffused mixing liquid is impacted and diffused by the rotating impeller, so that the mixing liquid is further refined and the mixing efficiency is improved, and the impeller scrapes off the soap nuts and impurities above the screen through rotation.

The present invention discloses a transparent super-hydrophobic cultural relic protection material and a preparation method thereof. The method first grafts a hydrolyzed silane coupling agent onto the surface of silica, and then utilizes the amino group of the hydrolyzed silane coupling agent to react with the carboxyl group of a chain fatty acid to graft a chain alkyl group onto the surface of silica particles. The prepared material has excellent super-hydrophobicity, a large contact angle of water droplets on the coating surface, and a small rolling angle, making it difficult for water droplets to stay on the coating surface, thereby effectively preventing moisture penetration. At the same time, due to the transparency of the silica particles and the chain fatty acid, the coating can maintain a high transparency and will not block or change the original color and pattern of the cultural relic. The silane coupling agent acts as a bridge connecting the silica particles and the chain fatty acid, which can enhance the chemical bonding inside the coating, making the coating less prone to aging and cracking, and giving the material good high-temperature resistance and the advantage of resisting ultraviolet light, thereby extending the preservation life of the cultural relic.

The invention discloses a synthesis method of an insulin analogue, which comprises the following steps of: firstly, obtaining A-chain peptide resin by using a solid-phase synthesis method, constructing a disulfide bond between A6 and A11 on a solid phase, and cracking the A-chain peptide resin by using a cracking solution containing a sulfydryl activator to obtain a peptide chain with an activated sulfydryl group and a protected sulfydryl group; then a solid-phase synthesis method is used for obtaining B-chain peptide resin, Lys side chain protecting groups are removed on a solid phase in a fixed-point mode, side chain fatty acid modification is completed, and a peptide chain with an exposed sulfydryl group and a protected sulfydryl group is obtained after cracking is conducted through a cracking solution; and mixing the products in a solution according to a certain proportion to form a first pair of intermolecular disulfide bonds, and constructing and purifying the last pair of disulfide bonds to obtain the insulin analogue. The method disclosed by the invention has the advantages of convenience in synthesis, low cost, simple process and the like, can be used for research on amino acid mutation of insulin compounds, and has important practical significance on development of insulin drugs.

The invention relates to the technical field of astaxanthin oil, in particular to a preparation method of astaxanthin oil, which comprises the following specific steps: mixing haematococcus powder with double-particle-size glass beads, adding coconut oil, and oscillating; then cellulase is added for a hydrolysis reaction, enzyme is inactivated after hydrolysis, and a wall-broken mixture is obtained; carrying out primary extraction and secondary extraction on the wall-broken mixture, combining the two extracting solutions, and filtering; performing supercritical CO2 extraction on the filtrate to obtain primary astaxanthin oil; mixing the primary astaxanthin oil with a 1-butyl-3-methylimidazole hydroxide ethanol solution, and introducing nitrogen to carry out a reaction; cooling and filtering after the reaction is finished, and finally desolventizing under reduced pressure to obtain the astaxanthin oil. In the design, the 1-butyl-3-methylimidazole hydroxide can efficiently hydrolyze lipid impurities in the astaxanthin oil to generate water-soluble fatty acid salt and glycerol, so that the separation efficiency is improved, and the separation effect is further optimized.

The invention relates to a probiotic fermented fruit and vegetable juice beverage and a preparation method thereof, and belongs to the technical field of food. The invention provides a preparation method of a probiotic fermented fruit and vegetable juice beverage, which mainly comprises the following steps: mixing fruit and vegetable raw materials with deionized water, homogenizing at high pressure, adding polydextrose and resistant starch, stirring for dissolving, sieving, adjusting the pH value, adding pectinase and cellulase, performing enzymolysis, inoculating compound bacteria into enzymatic hydrolysate, performing two-stage fermentation, and obtaining the probiotic fermented fruit and vegetable juice beverage. And adding a fructus momordicae extract into the obtained fermentation liquor, sieving, carrying out pasteurization, immediately cooling to 4 DEG C, filtering, and carrying out sterile filling, thereby obtaining the fructus momordicae health-care wine. The apple, the kale, the jerusalem artichoke, the mandarin orange, the momordica grosvenori extract and the like are compounded to provide multiple trace element supplementation for a human body, lactic acid and short-chain fatty acid are generated in the synergistic double-bacterium fermentation process, and intestinal tract movement is effectively promoted.