31 results about "Bypass surgery" patented technology

The utility model discloses a cardiac muscle patch with a microneedle for cardiac bypass, which comprises a patch main body used for being adhered and wrapped on the surface of a vein bridge blood vessel in a cardiac bypass operation; the plurality of microneedles are uniformly distributed on the adhesive surface of the patch main body, and drug particles are attached to the surfaces of the microneedles; and the reinforced connection structures are uniformly distributed on the surface of the patch main body, are connected to the interiors of the microneedles, and are used for reinforcing the connection between the microneedles and the patch main body. According to the myocardial patch with the micro-needle for heart bypass, the surface of the patch is combined with the hydrogel micro-needle to form an integrated structure, so that loaded drugs, such as antiplatelet tirofiban sustained-release particles, are loaded to the needle body of the micro-needle, and continuous and stable release of the tirofiban sustained-release particles can be ensured; the myocardial patch is directionally conveyed to a vein bridge area, so that simple and convenient application of the myocardial patch in a vein bridge is facilitated.

The invention relates to the field of medical instruments and public health, in particular to an artificial blood vessel with anticoagulation, endothelium promotion and bending resistance functions and a preparation method of the artificial blood vessel, and the artificial blood vessel is used for various blood vessel replacement and blood vessel bypass operations and has the characteristics of anticoagulation, endothelium promotion and bending resistance. The copper-containing material and the degradable magnesium-based metal material are respectively integrated on the inner surface of the artificial blood vessel and in the interlayer of the vessel wall, so that the functions of anticoagulation, endothelium promotion and bending resistance of the artificial blood vessel are realized. According to the artificial blood vessel with the anticoagulation, endothelium promotion and bending resistance functions, in the initial stage of use, due to the spiral structure of the magnesium alloy wire, the blood vessel cannot collapse after being bent, the blood flow is kept smooth, copper ions, magnesium ions and a small amount of hydrogen can be released to surrounding tissues in the use process, the microenvironment of the surrounding tissues is adjusted to be alkalescent, and the blood circulation is kept smooth. Through the synergistic effect of the copper ions and the magnesium alloy, the effects of promoting endothelialization, resisting blood coagulation and adjusting the acid-base property of the microenvironment are achieved at the same time, and therefore the functions of resisting blood coagulation, promoting endothelium and resisting bending are achieved.

The invention discloses a proximal anastomosis auxiliary device in coronary artery bypass grafting, and relates to the technical field of medical instruments. Comprising a puncture needle, a puncture cannula and an annular compressor. The puncture needle is sleeved with the puncture cannula, and a bulged ball is arranged at the head end of the puncture cannula; the annular compressor is arranged outside the puncture cannula in a sleeving mode and can slide in the axial direction, a compression ring with a notch is arranged at the head end of the annular compressor, and the inner diameter of the compression ring is smaller than the outer diameter of the bulging ball. During puncture, the annular compressor is pressed down after puncture enters the aorta, and the compression ring and the bulging ball cooperate to clamp and close a puncture point to achieve blood-free operation; after the aorta wall in the compression ring is cut off, the bridge vessel is matched with the aorta, and the suture passes through the compression ring together; after suturing is completed, the annular compressor is rotated, the suture retreats from the notch, the suture is tightened and knotted after the whole device is withdrawn, and anastomosis is completed. The aorta forceps clip operation is avoided, the plaque falling risk is eliminated, anastomosis can be completed only through a single hole, operation is easy and convenient, hemostasis is reliable, and cost is low.

The present invention involves a novel method of reducing the risk of developing atrial fibrillation (AF) and / or atrial flutter (AFL) post coronary bypass surgery (CABS) by administering, to patients who have undergone CABS, loading and maintenance doses of dofetilide intravenously followed by oral doses.

An aorta remaining needle comprises a puncture needle and a sleeve, a flow channel is arranged in the sleeve in the axial direction, the front end of the puncture needle penetrates through the flow channel and extends to the front portion of the sleeve, a first connector is arranged at the rear end of the sleeve, a bulging ball is arranged at the front end of the sleeve, and the bulging ball is distributed on the periphery of the sleeve in the circumferential direction of the sleeve. A side pipe is connected to the side face of the sleeve, a second connector is arranged at the rear end of the side pipe, a side connector is arranged on the side wall of the second connector, a first water stop clamp is arranged on the side pipe, and a second water stop clamp is arranged on the portion, between the bulging ball and the first connector, of the sleeve. In a non-stop bypass surgery, the indwelling needle is used for puncturing, the contact area between the indwelling needle and the aorta wall can be increased through the bulged ball, and therefore the stability and reliability of fixing of the indwelling needle are improved, the side connector is connected with the silica gel hose, blood can be rapidly supplied to far-end ischemic myocardium, and the operation is convenient. And the possibility of occurrence of myocardial avascular necrosis and malignant arrhythmia is reduced. The indwelling needle can also be connected with the free great saphenous vein, hormone or nitroglycerin is injected to the ischemic myocardium after the far-end anastomotic stoma is completed, great saphenous vein bridge can be conveniently cut under the condition of hyperemia expansion, and therefore the optimal length is designed for the bridge blood vessel.

The utility model discloses a great saphenous vein taking body position pad for a bypass surgery, which comprises a base plate, a popliteal space pad is arranged in the middle of the base plate and can move back and forth along the base plate, a heel placing area is arranged at the foot of the base plate, and a telescopic supporting mechanism is arranged on the lower surface of the rear of the base plate and is used for adjusting the inclination of the base plate. A fixing belt is additionally arranged behind the base plate; the whole structure is suitable for being placed at the tail of a bed, on one hand, a patient can adjust the position of the popliteal space pad according to the actual length of the lower limb, so that the different lengths of heels and popliteal spaces of different patients can be correspondingly adjusted, the whole product is suitable for different patients, the use is flexible, and the application is wide. On the other hand, the popliteal fossa pad of the lower limb can effectively prevent nerve injury.

The present article relates to an artificial graft (artificial blood vessel) used in surgical procedures such as bypass surgery (such as implantation of an artificial blood vessel).

The invention discloses a blocker for an intracranial ventricular temporal angle-frontal angle bypass pipeline, which comprises a blocker body with a cylindrical structure, one end of the blocker body is coaxially and fixedly provided with a first joint, and the other end of the blocker body is coaxially and fixedly provided with a second joint; the first joint and the second joint are respectively arranged in a foreangle single-cavity branch tube of the double-cavity ventricular canal and are bound and fixed, so that a passage of the foreangle single-cavity branch tube of the double-cavity ventricular canal is blocked. By means of the blocker, a traditional wire outside-tube ligation mode can be changed into an inside-tube blocking and outside-tube fixing combined mode, the blocking accuracy and stability of the blocker are improved, leakage of cerebrospinal fluid is effectively prevented, a solid guarantee is provided for operation prognosis, in the whole operation process, damage to the tube wall of a double-cavity ventricular canal is avoided, and the blocker is suitable for popularization and application. And the integrity of the original structure of the double-cavity ventricular canal is maintained to the greatest extent.

The application belongs to the technical field of biological medicine, and particularly relates to a pharmaceutical use of a Hedgehog pathway inhibitor in preventing and treating vascular remodeling and restenosis after an arterial bypass operation and improving the survival rate of a coronary heart disease patient after the arterial bypass operation. The abnormal proliferation of smooth muscle cells driven by endothelial cell activation can be obviously inhibited by the Hedgehog pathway inhibitor GDC-0449 intervention, and the inflammatory reaction can be effectively reduced. In the in-vivo experiment, the local application of GDC-0449 to the bypass artery can significantly relieve the remodeling and stenosis of the bypass artery, and provide a theoretical basis and strong support for the molecular targeted treatment strategy of the vascular remodeling and failure after the arterial bypass operation.

Provided are a suction attachment and a stabilizer provided with the suction attachment, the suction attachment being capable of sufficiently suppressing vibration due to beating of the heart during a coronary artery bypass surgery on a contact portion of the suction attachment, and being capable of avoiding the problem of breakage after the coronary artery bypass surgery. A suction attachment (50) attached to a stabilizer (100) that suppresses vibration of the heart surface of a patient receiving coronary bypass surgery is provided with a flexible channel (60) that forms a suction flow path (61) together with the heart surface when in contact with the heart surface of the patient, and the flexible channel (60) has a C-shaped tunnel shape that serves as a passage for a transplanted blood vessel.

A powder formulation for preserving tissue and organ function, and more particularly to shelf stable powder formulations that can be reconstituted at point of use, including during a fat grafting process, coronary artery bypass graft surgery, and peripheral bypass surgery, or other grafting / transplant surgery prior to or during the medical procedure to preserve the tissues / organs used in these procedures. The powder formulation includes a reducing agent; an antioxidant; a sugar; a nitric oxide substrate; a buffering agent; and physically acceptable salt. Also provided are a method of preparing an organ or tissue preservation solution by reconstituting the powder formulation, and a method of preserving tissue or an organ using same.

The present invention involves novel safe dosage regimens comprising the administration of a loading and maintenance dose of dofetilide iv, followed by oral dosing of dofetilide. Methods include (a) reducing the risk of developing atrial fibrillation (AF) and / or atrial flutter (AFL) post coronary bypass surgery (CABS); (b) terminating arrhythmic storm in patients following implementation of an implantable defibrillator by administrating loading and maintenance infusions of dofetilide intravenously followed by oral dosing; and, (c) converting atrial fibrillation (AF) or atrial flutter (AFL) in a patient presenting with highly symptomatic AF or AFL.

A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.

The intracranial ventricular temporal angle-frontal angle bypass pipeline comprises a three-way flow guide pipe, a frontal angle hydrotubation pipe and a connector, the first end of the three-way flow guide pipe is arranged in a ventricular temporal angle, and the second end of the three-way flow guide pipe is detachably connected with one end of the frontal angle hydrotubation pipe through the connector; the connecting joint is used for blocking / communicating the second end part of the three-way flow guide tube and the frontal angle hydrotubation tube, the other end of the frontal angle hydrotubation tube is arranged in the frontal angle of the ventricle, and the third end of the three-way flow guide tube is used for being connected with a liquid storage bag below the scalp or being led out of the scalp. According to the bypass pipeline for the bypass surgery, the three-way flow guide pipe is adopted, the third end of the three-way flow guide pipe is used for being connected with the liquid storage bag or leading out the scalp, and a cerebrospinal fluid sample can be reserved for testing by means of the third end of the three-way flow guide pipe, so that clinical diagnosis is assisted; meanwhile, the end can be used for implementing liquid pumping and pressure reducing operation so as to reduce intracranial pressure.

The present invention discloses a robotic assisted system for ophthalmic surgery, comprising a first driving unit, a second driving unit and a third driving unit, wherein the three driving units can respectively complete the movement in three dimensions, the first driving unit is connected with the second driving unit, the second driving unit is connected with the third driving unit, and an instrument is arranged on the third driving unit; during operating, the third driving unit can drive the instrument assembly to move, the second driving unit can drive the third driving unit and instruments thereon to move, and the first driving unit can drive the second driving unit, the third driving unit on the second driving unit and the instruments on the third driving unit to move; the accurate control on the instruments can be completed by controlling the three different driving units. Through the specific RCM structure, the advantages of high precision and compact structure are achieved, and the present invention is suitable for various eye surgeries such as retinal bypass surgery, sub-retina injection and vitrectomy. The ophthalmic surgical device of the present invention has extremely high safety.

The invention relates to the technical field of surgery planning, in particular to a minimally invasive bypass surgery planning method based on multi-modal image fusion, which comprises the following steps: acquiring heart dynamic parameters; generating a dynamic three-dimensional model; calculating a blockage risk score, and determining an initial anastomosis angle of the bridge blood vessel and the target blood vessel according to the blockage risk score; determining the fluctuation range of the matching angle; acquiring the variation range of the eddy current intensity value, judging whether the matching angle meets the requirement or not, and correcting the matching angle in response to the inconformity of the requirement; and determining the anastomosis position of the bridge blood vessel and outputting an operation planning scheme. According to the method, the blockage risk of the bridge blood vessel is quantified by combining the past medical history and blood routine parameters in the medical record of the patient to obtain the blockage risk score, the corresponding anastomosis angle is determined according to the blockage risk score, and the anastomosis angle is corrected according to the vortex intensity value; therefore, the accuracy of the minimally invasive surgery is improved, and the risk of blockage of the bridge blood vessel after the surgery is reduced.

A method for improving neurobehavioral outcomes in neonates or infants undergoing cardiac bypass surgery by administering BM-MSCs, BM-MSC derived exosomes, or BM-MSC miRNA into CPB bypass circuit. Compositions comprising BM-MSCs or their products such as exosomes or miRNA are also aspects of the invention as is a kit suitable for performing the methods disclosed herein.

The present article relates to an artificial graft (artificial blood vessel) used in surgical procedures such as bypass surgery (such as implantation of an artificial blood vessel).

A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.

The invention relates to the technical field of medical instruments, in particular to a coronary artery bypass postoperative rehabilitation training device which comprises a bottom frame, supporting rods, a top frame, a seat plate and a back plate, the supporting rods are arranged at the top end of the bottom frame, the top ends of the supporting rods are connected with the bottom end of the top frame, and the seat plate is fixedly installed at the top end of the top frame. The back plate is fixedly installed on the rear side of the top end of the seat plate, the lifting assemblies are fixedly connected with the supporting rod and the top frame, the training assemblies are installed on the lifting assemblies, the handrail assemblies are arranged on the left side and the right side of the top frame respectively, and the lifting assemblies are fixedly connected with the supporting rod and the top frame. The training assembly is used for actively and passively exercising quadriceps femoris muscles of a patient; through an active training mode and a passive training mode, rehabilitation training of a patient is achieved, and flexibility is improved.

Reinforced external graft support assemblies and methods of manufacture and implantation are provided herein. In particular, graft support assemblies are composed of single or multilayer sheaths designed to provide mechanical support to vascular conduits during cardiovascular bypass surgery. Graft sheath systems may be fabricated using 3D printing techniques with biocompatible materials incorporate surgical design considerations such as mechanical strength, flexibility, porosity, and the ability to be tailored to specific anatomical structures. External graft sheaths may include one or more layers of various biomaterials to produce customized biomechanical properties including varied time courses of degradation. Furthermore, these customizable features may incorporate standardized designs or be tailored for individual patients depending on medical and surgical history, or other pertinent geometric attributes measured in pre-operative medical imaging. These methods protect vascular conduits, particularly venous grafts, from adverse remodeling and graft failure, thereby providing precision medicine solutions to cardiovascular bypass surgery.

The present invention discloses a coronary shunt plug forceps, comprising an upper handle, a lower handle, a bifurcation head and an elbow, wherein one end of the upper handle is fixedly connected to one end of the lower handle, the other end of the upper handle is provided with a bifurcation head, and the other end of the lower handle is provided with an elbow, and the elbow is bent toward one side of the bifurcation head. The present invention belongs to the technical field of medical devices, and the purpose of the present invention is to solve the problem of great operational difficulty when using ordinary bypass forceps to control the angle of the shunt plug in the prior art. The technical effect achieved is: through the coronary shunt plug forceps of the present invention, the difficulty of placing the shunt plug is significantly reduced, the risk of off-pump bypass surgery is significantly reduced, and intraoperative bleeding is reduced; the one-handed operation of placing the shunt plug is realized, and the difficulty of the operation is reduced.

A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.

The invention belongs to the technical field of cardiac surgery instruments, and particularly relates to a suction device applied to coronary artery bypass surgery, which comprises a nursing trolley, a first placing plate is fixedly mounted at the lower end of the nursing trolley, a second placing plate is fixedly mounted at the upper end of the nursing trolley, and the first placing plate and the second placing plate are arranged in parallel up and down; four groups of universal wheels are fixedly mounted at the lower end of the nursing trolley, protective side plates are fixedly mounted on the front side, the rear side, the left side and the right side of a first placement plate at the lower end of the nursing trolley, and a negative pressure pump is fixedly mounted on the upper side of the right end of the first placement plate; through mutual cooperation of a negative pressure pump, a main pipeline, a blood storage tank, a tank cover and a branch pipe, a bent pipe suction head, a straight pipe suction head and a thin pipe suction head in a storage box are connected with a connector for replacement, then blood at a wound surface is sucked in the operation process, and the blood is absorbed and stored through the blood storage tank; and an undefined operation field caused by blood flow is avoided.

The utility model provides a pericardium double-cavity drainage tube used after heart bypass surgery, which comprises a plastic tube, a drainage tube, a drainage tube and a drainage tube, the plastic tube comprises a straight tube and an inclined tube in the length direction, and an acute angle is formed between the straight tube and the inclined tube; the plastic pipe is provided with a hollow double-cavity structure, the double-cavity structure comprises a drainage cavity and an eccentric hole cavity, the drainage cavity is not communicated with the interior of the eccentric hole cavity, and the drainage cavity extends to penetrate through the straight pipe and the inclined pipe; the eccentric hole cavity only extends to penetrate through the inclined pipe and does not extend to the straight pipe, an opening in one end of the eccentric hole cavity is located at an opening of the inclined pipe, and an opening in the other end of the eccentric hole cavity is located at the intersection position of the inclined pipe and the straight pipe.

A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.

The utility model relates to medical instrument technical field discloses heart bypass operation blood vessel fixing clamp, including the clamping plate, the inner wall sliding connection has rubber block in the clamping plate, the right side of clamping plate is provided with locking mechanism, locking mechanism is used for fixing clamping plate, avoids the loosening in clamping process, the front side of clamping plate is provided with replacement mechanism, replacement mechanism is used for replacement processing according to different size blood vessel, the locking mechanism includes the rack, the left end fixed connection in the inner wall left side of clamping plate of rack, the right side intercommunication of clamping plate has fixed box. In the utility model, through pressing clamping plate to blood vessel and clamping, at this time rubber block follows clamping plate and bends, simultaneously, the right end of rack passes through clamping plate and is connected in fixed box in sliding, through the pushing force of spring one under the top post, makes extrusion force act on rack, makes the close engagement of rack and tooth groove, realizes the locking processing of clamping plate.

The invention relates to the technical field of cardiac surgery, and particularly discloses a heart suspension mechanism and a using method thereof.The heart suspension mechanism comprises two connecting plates, and the opposite sides of the two connecting plates are connected with a plurality of first connecting belts; according to the heart suspension mechanism, through careful design and cooperative cooperation of all the components, in the fixing and suspension process of the heart and the cardiothoracic part, the end, away from the winding roller, of the suspension rope is connected to the heart stabilizer, and by means of the length adjusting effect of the suspension rope, a worker can adjust the suspension height and angle of the hearts of different patients, so that the heart suspension efficiency is improved. A more efficient, safer and more convenient fixing and hanging solution is provided for cardiac surgery and rehabilitation treatment, meanwhile, the device is suitable for bypass surgery with the requirement for the heart position, the surgery field is exposed, the risks of cardiac adventitia injury and cardiac rupture are reduced, the surgery difficulty of the bypass surgery of old patients is reduced, and the patient experience is improved. The risk of complications caused by the heart fixator in the operation is reduced, and the bypass operation is convenient to popularize.

A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.