22 results about "Angioplasty" patented technology

Pulsatile balloon catheter systems are provided. Aspects of the systems include: a pulse generator; and a balloon catheter assembly operably connected to the pulse generator. In embodiments, the balloon catheter assembly includes: a proximal connector operably connecting the balloon catheter assembly to the pulse generator and configured to transduce a first pulse energy generated by the pulse generator to a second pulse energy; a distal balloon; and a catheter component, where the catheter component includes a fluidic passage operably positioned between the proximal connector and the distal balloon, which passage is configured to propagate the second pulse energy from the proximal connector along the fluid passage to the distal balloon. Also provided are balloon catheter assemblies and kits that include the same. Also provided are systems and methods for assessing vessel compliance in-vivo. Also provided are systems and methods for determining system state of balloon catheter systems. The systems, assemblies and kits find use in a variety of different applications, including balloon angioplasty applications.

Various embodiments of the systems, methods and devices are provided comprising angioplasty to break up calcification or other tissue in occlusive areas within a blood vessel. The various embodiments disclosed comprise pressure pulse periods designed to break up calcified occlusive material through a cyclically stretching of the vessel walls without damaging the vessel wall tissue.

The invention relates to a catheter system for carrying out an angioplasty, comprising an outer shaft which extends in an axial direction and has a distal end, an inner shaft which can be moved therein in the axial direction and has a distal end, and a rolling membrane which is connected to the distal end of the outer shaft and the distal end of the inner shaft in a pressure-tight manner, and which can be moved between a rolled-in position within the outer shaft and a position in which it is rolled out distally from the outer shaft by applying pressure.

Systems and methods can involve wedge dissectors attached to strips in turn attached to medical balloons, for forming serrations within vascular wall tissue for angioplasty as well as drug delivery. Such balloon blowing techniques can reduce the balloon profile, the material costs, and the manufacturing time to build a serrated balloon catheter device. The design and process to build this type of balloon is described herein.

The present invention relates to a device (4) for automatically inflating a vascular balloon catheter (6) with a fluid, the device (4) comprising a catheter interface (8), a fluid supply device (12), a pressure sensor device (16), and a control device (18). The catheter interface (8) is particularly designed to be removably connectable to the balloon catheter (6) without tools, thereby allowing fluid to flow from the device (4) to the balloon catheter (6) via the catheter interface (8). The fluid supply device (12) is designed to discharge fluid from the device (4) at the catheter interface (8) by a motor (32). The pressure sensor device (16) is designed to measure the pressure of the fluid discharged from the device (4). The control device (18) is designed to control the amount of fluid discharged from the device (4) by the fluid supply device (12) by driving the motor (32) of the fluid supply device (12) based on the pressure measured by the pressure sensor device (16). According to the present disclosure, the fluid supply device (12) is designed to allow fluid to be drawn into the device (4) at the catheter interface (8) by a motor (32). The present disclosure further relates to a system (2; 102; 202; 302) for performing angioplasty, comprising a balloon catheter (6) and a device (4) according to the present disclosure.

Microcatheter systems for crossing total occlusions are provided. Aspects of the systems include: a microcatheter with proximal and distal regions, the distal region comprising a fixed, sealed end, wherein the microcatheter comprises a lumen that receives liquid and gas, a fluid introduction module for introducing liquid and gas into the microcatheter lumen and an actuator that repeatedly pressurizes a liquid and gas mixture present within the microcatheter lumen such that the distal region of the microcatheter vibrates, moving the microcatheter across a total occlusion. Also provided are methods for modulating a total occlusion, e.g., by crossing a total occlusion or modifying a proximal cap thereof, e.g., by producing a divot or hole in the proximal cap. The systems and methods find use in a variety of different applications, including balloon angioplasty applications or other catheter-based therapies or treatments, such as conditions in which a total occlusion may be present in a vessel, including, for example, cardiovascular disease.

The ultrasonic system includes an ultrasonic device having an ultrasonic transducer and a core wire having a proximal end coupled to the ultrasonic transducer and a distal end portion terminating at a distal tip. An ultrasonic energy source is electrically connected to the ultrasonic transducer. The ultrasonic energy source includes an ultrasonic signal generator circuit, a modulator circuit, and a controller. The ultrasonic signal generator circuit generates an ultrasonic electrical signal. The modulator circuit amplitude-modulates the ultrasonic electrical signal with a macromotion electrical signal to generate a modulated ultrasonic electrical signal. The controller executes program instructions to select between an engagement mode and a transverse mode, where in the engagement mode, a first ultrasonic electrical signal is provided from the ultrasonic energy source to the ultrasonic transducer, and in the transverse mode, a modulated ultrasonic electrical signal is provided from the ultrasonic energy source to the ultrasonic transducer.

We provide a pulsating balloon catheter system. [Solution] The system comprises a pulse generator and a balloon catheter assembly operably connected to the pulse generator. In the embodiment, the balloon catheter assembly comprises a proximal connector configured to operably connect the balloon catheter assembly to the pulse generator and convert a first pulse energy generated by the pulse generator into a second pulse energy, a distal balloon, and a catheter component, the catheter component comprising a fluid passage operably positioned between the proximal connector and the distal balloon, the fluid passage configured to propagate the second pulse energy from the proximal connector along the fluid passage to the distal balloon. The system, assembly, and kit find use in a variety of different applications, including balloon angioplasty applications.

A catheter system includes a rolling membrane guiding catheter and a docking unit. The docking unit is configured to automatically insert a plurality of devices into the rolling membrane guiding catheter.

This invention discloses a pulse-release balloon dilation pump and method for intracranial arterial stenosis. Addressing the mechanical mechanism of thin intracranial arterial walls and irregular plaques leading to axial stress accumulation and subsequent complications such as dissection and detachment, this invention adds a pulse-release control unit to a conventional pressure pump. Its core physical principle is as follows: When the balloon dilates at an irregular plaque, the intramural strain energy density distribution is uneven. Static friction constraint keeps the system in a high-energy metastable state, and the accumulated elastic potential energy ΔU continuously increases with expansion. The constraint factor λ is defined as F_required / f_max; when λ>1, the balance is unstable, and energy suddenly bursts. This invention uses periodic short-term pressure release to instantaneously decrease the contact pressure, reduce the static friction limit, and briefly raise λ to >1, actively triggering micro-slippage, releasing a small portion of the accumulated energy each time, achieving segmented and gentle energy release. Pulse parameters (amplitude, frequency, etc.) can be flexibly adjusted according to actual clinical conditions. The pulse mode offers flexible and diverse usage options. Operators can initiate it synchronously in the early stages of dilation, when risk signs appear, intervene as needed during pressure application, or combine multiple methods, allowing the operator to independently determine the operational procedure. Based on thin-film mechanics, tribology, and viscoelasticity theories, this invention is simple to operate, does not alter the clinical procedure, and effectively reduces the risk of complications during intracranial artery stenosis balloon angioplasty.

The invention discloses a wireless pressure monitoring system for balloon dilatation and a data recovery method. The system comprises a tubular wireless pressure sensing unit connected between a pressure pump and a catheter, and a medical pressure sensor with an isolating membrane design is adopted in the tubular wireless pressure sensing unit to ensure safety; and the independent display is arranged beside the radiography main screen. The display provides digital display which is intuitively compatible with a mechanical dial plate and has higher precision, the whole operation process from negative pressure exhaust to positive pressure expansion is completely covered, and the numerical value is accurate to one decimal point. The system collects data in a fixed period and records timestamps, and pressure data and radiography perspective videos can be accurately matched and repanned through the timestamps after an operation. A traditional manual counting mode is directly replaced, the problems of information splitting, high cognitive load and data black box are solved through medical-level safety design, full-process quantitative display and visual field unification, existing equipment does not need to be transformed, the structure is simple, and clinical popularization is easy.

Microcatheter systems for crossing total occlusions are provided. Aspects of the systems include: a distal crosser unit and an actuator. In embodiments, the distal crosser unit comprises: a microcatheter having a guidewire lumen; a guidewire present in the guidewire lumen and extending beyond the distal end of the microcatheter; a proximal balloon attached to both the microcatheter and the guidewire, wherein the proximal balloon is configured to longitudinally expand; and a distal anchor member present on the guidewire. In such embodiments, the actuator is configured to sequentially inflate and deflate the proximal balloon such that the distal crosser unit progressively moves across a chronic total occlusion. Also provided are methods for modulating a total occlusion, e.g., by crossing a total occlusion or modifying a proximal cap thereof, e.g., by producing a divot or hole in the proximal cap. In addition, standalone distal crosser units and kits comprising components of the systems described herein are provided. The systems, units, methods and kits find use in a variety of different applications, including balloon angioplasty applications or other catheter-based therapies or treatments.

The present invention relates to a supply device for storing and transporting catheters, particularly balloon catheters for percutaneous transcatheter coronary angioplasty, the supply device comprising a support and a retaining device disposed or formed on the support for holding a catheter wound annularly in a storage position, the retaining device comprising at least three retaining elements that engage with the catheter in the storage position, the at least three retaining elements disposed or formed on the support spatially separated from each other.

The invention discloses a steady state judgment method and system for an intracranial artery stenosis balloon dilatation, which are used for solving the problem that the prior art depends on subjective experience and lacks quantitative criteria. The method comprises the following steps: synchronously acquiring a balloon perspective image and system pressure data in real time; extracting the minimum inner diameter (D) and the pressure (P) of the balloon; continuously calculating the instantaneous change rate (V) of D and P and the trend change rate (S) based on the time window by taking the change rate percentage per second (% / second) as a unified dimension; and based on the steady-state threshold (theta f) and the steady-state threshold (theta s), rapid steady-state judgment is performed after pressurization pause, and continuous steady-state judgment is performed in the maintenance stage. The system comprises various functional modules for realizing the method. The judgment result is subjected to silent feedback by changing visual attributes such as an instantaneous change rate curve and the like. According to the method, conversion from experience driving to data driving is achieved, objective decision support is provided for individualized precise expansion, and the purpose of synchronously improving operation safety and efficiency is achieved.

The present disclosure provides pro-angiogenic proteoglycan mimetics that can provide a provisional, pro-angiogenic scaffold to support tissue regeneration while limiting systemic exposure to VEGF activity. These mimetics can protect a collagen matrix from rapid degradation, and in conjunction with EPCs promote angiogenesis in order to accelerate ischemic wound healing. For example, the provided compounds can be delivered from the end of a catheter following balloon angioplasty to coat the collagen exposed areas, prevent platelet binding and thrombosis, support capture of EPCs from blood to facilitate reendothelialization, and reduce late-lumen loss (neointimal hyperplasia).

Methods, devices, and systems establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures, such as stenting and angioplasty, atherectomy performed through a transcarotid approach or transfemoral into the common carotid artery, either using an open surgical technique or using a percutaneous technique, such as a modified Seldinger technique or a micropuncture technique.

A device and method for intravascular treatment of atherosclerotic plaque prior to balloon angioplasty which microperforates the plaque with small sharp spikes acting as serrations for forming cleavage lines or planes in the plaque. The spikes may also be used to transport medication into the plaque. The plaque preparation treatment enables subsequent angioplasty to be performed at low balloon pressures of about 4 atmospheres or less, reduces dissections, and avoids injury to the arterial wall. The subsequent angioplasty may be performed with a drug-eluting balloon (DEB) or drug-coated balloon (DCB). The pre-angioplasty perforation procedure enables more drug to be absorbed during DEB or DCB angioplasty, and makes the need for a stent less likely. Alternatively, any local incidence of plaque dissection after balloon angioplasty may be treated by applying a thin, ring-shaped tack at the dissection site only, rather than applying a stent over the overall plaque site.

Systems and methods can involve wedge dissectors attached to strips in turn attached to medical balloons, for forming serrations within vascular wall tissue for angioplasty as well reducing vessel recoil, reducing residual stenosis, and increasing volumetric blood flow post angioplasty. The design, methods of use, intended outcomes, and process to build this type of balloon is described herein.

A system includes a processor in communication with a memory. The processor is configured to receive one or more images of an implantable device within a vascular system; extract at least one image feature from the one or more images, the at least one image feature indicating the position of the implantable device relative to the vascular wall of the vascular system; and select at least one view based on the at least one image feature for optimal observation of a medical procedure involving the deployment of the implantable device to the vascular wall.

This document relates to methods and materials for treating vascular stenosis. For example, nanoparticles (e.g., poly lactic-co-glycolic acid (PLGA) nanoparticles) including one or more inhibitors of a monocyte chemoattractant protein (MCP) polypeptide (e.g., bindarit) are provided. In some cases, a composition (e.g., a hydrogel composition) including one or more nanoparticles including one or more inhibitors of a MCP polypeptide (e.g., bindarit) can be placed in direct contact with an adventitia of one or more blood vessels (e.g., one or more blood vessels at risk of stenosis formation) within a mammal (e.g., a mammal such as a human that underwent an angioplasty) to reduce or eliminate stenosis formation in the blood vessel(s).

A method of performing angioplasty includes accessing an artery, inserting a tubular balloon into to the artery in a low-profile operating mode, the tubular balloon constrained in a generally helical shape, and forming a lumen within the generally helical shape by expanding the tubular balloon into a high-profile operating mode. A system for creating a lumen is also disclosed.

An artificial heart valve angioplasty ring is a ring body comprising a support tube, the outer layer of which is a biocompatible medical implantable polyester fabric, and an inner core inside the support tube. The inner core adopts an inner core cluster structure, which is composed of multiple similar concentric coils. The angioplasty ring has better support and myocardial compliance, and the gap between the silicone tube and the inner core filaments further enhances its support and compliance. The clusters of finer inner core filaments with gaps contribute to the lightweight design of the angioplasty ring.