134 results about "Stent implantation" patented technology

The invention discloses a method for training a prediction model for predicting blood vessel deformation after stent implantation. Comprising the following steps: respectively performing three-dimensional reconstruction processing on acquired pre-operation brain image data before stent implantation and post-operation brain image data after stent implantation to obtain a pre-operation blood vessel model and a post-operation blood vessel model; mapping the pose information of the stent in the postoperative craniocerebral image data to the preoperative blood vessel model to generate a stent model; constructing a target vascular graph structure based on the preoperative vascular model and the stent model, and constructing a target stent graph structure based on the stent model; a first node on the target vascular graph structure carries first physical coding information; a second node on the target support graph structure carries second physical coding information; and inputting the target blood vessel graph structure, the target stent graph structure and the postoperative blood vessel model into a graph neural network model for training until a set training ending condition is reached, thereby obtaining a prediction model. The rapid and accurate prediction of the blood vessel deformation after the stent is implanted is realized.

A pacing system (100) for wireless extra-cardiac pacing of a heart (303) of a patient (301). The pacing system (100) includes a generator (102), a transmitter (104), and an implant device (106). The generator (102) is configured to generate energy. The transmitter (104) is configured to transmit the energy generated by the generator (102). The implant device (106) including an expandable stent that is configured to be implanted in the heart (303) of the patient (301), the implant device (106) including a receiver (220) that is configured to receive the energy that is transmitted by the transmitter (220), the implant device including a transducer (222) that is configured to transduce the energy into a pacing stimulus that is configured to pace the heart (303).

The invention provides a medical stent and a preparation method thereof.The preparation method comprises the steps that an anti-coagulation coating is arranged on at least part of the surface of the medical stent through physical coating, then an anti-hyperplasia coating is arranged on at least part of the surface of the medical stent through physical coating, the anti-coagulation coating comprises a copolymer, and the anti-hyperplasia coating comprises an anti-hyperplasia coating. A copolymer in the anticoagulant coating contains a zwitterionic unit and an adsorption unit, and the anti-hyperplasia coating contains an anti-hyperplasia drug and a degradable polymer; or, an anti-hyperplasia and anti-coagulation integrated coating is arranged on at least part of the surface of the medical stent through physical coating, the integrated coating contains a copolymer and an anti-hyperplasia drug, and the copolymer in the integrated coating contains a zwitter-ion unit, an adsorption unit and a degradable unit; the adsorption unit is an ester unit containing a carbon-carbon double bond, and the degradable unit is a 2-methylene-1, 3-dioxane unit. The problem that thrombus and restenosis exist at the same time after the stent is implanted can be solved, the binding force between the coating and the substrate is improved, and the falling risk of the coating is reduced.

The invention relates to a stent conveying device and a stent system comprising the same. The support conveying device comprises a pushing rod. The force buffering component is arranged at the far end of the pushing rod and comprises at least one force conduction component, a non-zero angle is formed between the force conduction component and the axial center line of the pushing rod, and the distance between the far end of the force conduction component and the whole far end of the stent conveying device is smaller than or equal to the nominal diameter of a stent conveyed by the stent conveying device. When the axial pushing force applied to the near end of the pushing rod enables the near end of the stent conveying device to move in the axial direction by a distance not exceeding half of the axial length of the force conduction component. According to the stent conveying device, the pushing force transmitted to the blood vessel wall can be regulated and controlled, so that the force applied to the blood vessel wall in the pulling and / or pushing process is always in a controllable low force value range, the mechanical stimulation and potential injury risk to the blood vessel wall are reduced, and the stent implantation safety is improved.

The invention provides a covered stent and a stent system.The covered stent comprises a main stent body and a wrapping part, the main stent body comprises a main corrugated ring and a main covering film, the main corrugated ring is covered with the main covering film, and the wrapping part is connected to one side of the main stent body; the wrapping part wraps the main body stent in a releasable mode so that the main body stent can be compressed or unconstrained in the radial direction, the width of a certain position of the wrapping part is defined as W, and the perimeter of the covered stent at the position corresponding to the width W of the wrapping part is defined as C when the covered stent is in a natural expansion state, the relation between W and C meets the condition that W is smaller than or equal to C / 4. W is less than or equal to C / 4, so that the semi-constraint degree of the covered stent can be ensured, the stent can be repeatedly adjusted in the axial direction when being implanted into a blood vessel, and meanwhile, a channel convenient for selecting a branch blood vessel is provided when the covered stent is radially compressed by a wrapping piece, so that the movable space of the channel in the radial direction is not too large.

A method of providing embolic protection for carotid stent implantation includes advancing an arterial sheath into an arterial system of a patient and advancing a venous sheath into a venous system of the patient. A fluid connection may be established between the venous sheath and the arterial sheath to enable retrograde flow of blood through the arterial sheath. The artery sheath may be advanced through the vasculature into the patient's carotid artery and the inflatable balloon may be inflated within the patient's carotid artery to block smooth blood flow therein. An interventional tool may be advanced through the interior lumen of the arterial sheath, the interventional tool sized such that a portion of the cross-sectional area of the interior lumen of the arterial sheath remains open for retrograde flow of blood.

The present invention provides a cervical spinal canal expansion and molding bracket and implantation equipment, which relate to the technical field of medical devices. The cervical spinal canal expansion and molding bracket provided by the present invention adopts a first arm having a first connection part connecting to the side mass, and a second arm having a second connection part connecting to the spinous process. The first arm and the second arm are connected by a connecting piece. The relative movement of the first arm and the second arm is adjusted by the connecting piece to change the size of the incision. The bracket can be implanted and fixed in the initial state where the first arm and the second arm are not extended, and after implantation and fixation, the molding bracket can be extended by adjusting the connecting piece, thereby expanding the size of the incision, and then expanding the cross-sectional area of ​​the spinal canal, making it easier to ensure the stability of the implantation process of the cervical spinal canal expansion and molding bracket. The spinal canal expansion size can also be adjusted according to needs, and the surgical operation is more convenient.

The invention discloses a negative Poisson's ratio stent structure for heart and cerebral vessels and an optimization method of the negative Poisson's ratio stent structure, belongs to the technical field of medical instruments, and solves the problems of axial shortening, contradiction between radial supporting force and flexibility and low calculation efficiency in an optimization process of a traditional vascular stent due to a positive Poisson's ratio effect. Wherein a bracket structure of a curved-edge concave hexagonal geometric unit is adopted, and the bracket synchronously extends in the axial direction to present a negative Poisson's ratio effect when being subjected to an expansion load in the radial direction; degradable macromolecules or degradable metals are selected as the material of the stent; according to the optimization method, candidate design is generated through parametric modeling, performance indexes are obtained through finite element simulation, a neural network agent model is trained to predict multi-target performance, a Pareto optimal solution set is obtained through optimization by adopting a multi-target optimization algorithm, and manufacturing parameters are determined through finite element review. According to the invention, the implantation precision and the positioning accuracy of the stent are improved, the mechanical property and the biocompatibility are optimized, and the design efficiency is improved.

In an exemplary example, methods and systems are disclosed herein for treating vascular disease by implanting a stent within a vessel and using intravascular imaging to determine and ensure that the stent is properly implanted and produces the desired and effective results. For example, a system can obtain optical shape sensing data and intravascular imaging data of a vessel. The system can process the optical shape sensing data and the intravascular imaging data to generate three-dimensional models and images of the vessel immediately before and after the stent is implanted in the vessel and make an exact comparison of the before and after images to ensure that the stent is properly implanted and will produce or is producing the desired and effective results. The exact comparison can be based on a derived diameter associated with the location of the stent placement in the vessel, which is based on the generated pre- and post- three-dimensional models.

This application provides a stent placement device for cardiac surgery, comprising a cannula with an inlet end and an outlet end; the cannula is divided into 2-3 cannula branches at the inlet end; the cannula accommodates 2-3 stent delivery catheters; one stent delivery catheter is inserted from each cannula branch; all stent delivery catheters exit from the cannula outlet end; each stent delivery catheter has a guidewire lumen and a stent balloon pressure chamber; a guidewire is disposed in the guidewire lumen; a stent implanter is disposed at the tip of the stent delivery catheter, and an ultrasound positioning ball is sequentially disposed at the tip of the stent delivery catheter. This application utilizes a structure consisting of a flexible cannula and multiple stent delivery catheters to conveniently and simultaneously provide precise stent implantation for multiple blood vessels; by incorporating an ultrasound positioning ball with a corner reflector to enhance ultrasound reflection, the implantation and detailed operation of the device can be more easily completed under ultrasound monitoring.

A stent for insertion into a vessel of a patient includes an inner tube comprising a positive Poisson's ratio (PPR) material and defining a lumen extending along a longitudinal axis of the stent; and an outer tube comprising a negative Poisson's ratio (NPR) foam material and disposed around an entirety of the inner tube, the outer tube extending along the longitudinal axis of the stent. The stent is configured to exhibit an auxetic behavior in response to a deformation of the stent. An outer surface of the second portion is configured to apply a pressure to an inner surface of the vessel when the stent is implanted into the vessel and the deformation is removed.

A delivery device (10), which is used for delivering a stent implant (2) in a catheter (3) and comprises a delivery guidewire (1) and a pushing element (12). The delivery guidewire (1) comprises a stent compression section (11) for loading the stent implant (2), and a proximal portion of the delivery guidewire (1) connected to the proximal end of the stent compression section (11). The pushing element (12) at least comprises a distal-end pushing element (121). The distal-end pushing element (121) is fixed on the stent compression section (11) and is arranged at a position other than the proximal end of the stent compression section (11). When the delivery device (10) delivers the stent implant (2) in the catheter (3) to the distal end, the distal-end pushing element (121) pulls the stent implant (2) distally so as to push same, so that the stent implant (2) is in an axially pulled state. Therefore, such a configuration converts the mode of pressing the stent implant (2) to push same into the mode of pulling the stent implant (2) to push same, thereby avoiding the problem of increased pushing resistance caused by increased radial support force of the stent implant (2) itself during the delivery, and further reducing the risk and difficulty of delivery.

The present invention is entitled "Thrombectomy and Stent Implantation System". The present invention provides a design capable of both mechanical thrombectomy and stent implantation for the treatment of occlusions in the cerebral vasculature, which provides a three-catheter setup. A first outer catheter has the largest diameter and can serve as a guide catheter, while also serving as a sheath for the other catheters. A second deployment catheter can be configured for aspiration of the occlusion and can include a proximal stepped or recessed segment at the distal tip that can act as a housing for a woven expandable stent. The outer diameter of the stepped segment can be lined with an inflation device having a woven stent disposed on its top. Inside the second deployment catheter is a microcatheter that can deliver a mechanical thrombectomy device to the target site to retrieve the occlusion in the vessel, after which the stent can be expanded and implanted in the vessel.

Provided are a balloon stent installation device and a stent installation method. The balloon stent installation device, which is used to install a self-expandable stent to a lesion site of a blood vessel, includes a balloon dilatation catheter and a stent release tube. The balloon dilatation catheter includes a first through hole with an inlet and an outlet. An expansion part is disposed at a distal end of the balloon dilatation catheter. The self-expandable stent is slidably mounted in the first through hole and located at a distal end of the balloon dilatation catheter. The stent release tube is slidably disposed in the first through hole. A distal end of the stent release tube abuts against the self-expandable stent and includes a second through hole. A micro guidewire is configured to be inserted sequentially through the outlet of the first through hole, the self-expandable stent, and the second through hole.

A system and method for transesophageal echocardiogram-guided implantation of a stent are disclosed. The system includes at least a transesophageal echocardiogram (TEE) system, at least a display and at least a computing device configured to receive a plurality of ultrasound images, generate at least a three-dimensional (3D) cardiac model as a function of the plurality of ultrasound images, receive at least a 3D stent model, determine a view label for each of the plurality of ultrasound images and display the at least a 3D cardiac model and the at least a 3D stent model as a function of the view label.

This invention discloses a dynamic prediction system for long-term adverse cardiovascular event risk after stent implantation, belonging to the field of personal health risk assessment technology. It includes: a cardiovascular assessment module for determining the target cardiovascular adverse event presentation coefficient based on the target patient's first chest pain rating and real-time heart rate after stent implantation; a cardiac function assessment module for determining the emphasis of cardiac function analysis at each stage based on the target patient's physical examination data after stent implantation; a probability determination module for determining the probability of the first adverse event based on the target cardiovascular adverse event presentation coefficient and the emphasis of each cardiac function analysis; and an indicator determination module for comparing the target patient's first adverse event probability with the second adverse event probability of each monitored patient to obtain the target cardiovascular risk warning indicator for the target patient. This invention can improve the accuracy of long-term risk prediction for adverse cardiovascular events.

The present invention provides a valve stent and a usage method thereof for bicuspid aortic valve stenosis, comprising an ascending aorta contact area, a connecting body, a valve support area and a valve prosthesis suture part; the ascending aorta contact area is in an annular shape, a honeycomb-like structure formed by arranging and connecting a plurality of regular hexagons; the valve support area is in an elliptical annular shape, a grid structure formed by arranging and connecting a plurality of rhombuses. The present invention enhances the radial stiffness of the stent, thereby improving its radial support capacity; the valve support area is designed as an elliptical ring structure, and when implanting the artificial heart valve stent, the long-axis implantation angle of the valve stent is kept perpendicular to the long axis of the valve annulus, and by using the mutual coupling effect between the two, the cross-sectional shape of the expanded valve stent is finally circular, which improves the problem of poor expansion during the implantation of the valve stent and the elliptization after the valve stent is implanted, thereby reducing the occurrence of paravalvular leakage, with uniform stress and extended service life.

The present invention discloses a method for simulating aneurysm virtual stent implantation based on a spring analogy method. The method comprises: reconstructing a three-dimensional model of the preoperative parent vessel and the parent vessel after aneurysm restoration based on clinical imaging data; extracting the centerline of the first vessel to construct a virtual stent initialization model; deploying the virtual stent initialization model using a spring analogy virtual stent fast algorithm to determine the three-dimensional model of the virtual stent after deployment in the individualized vessel; and calculating efficacy evaluation parameters using a fast algorithm based on the arc surface porosity of the virtual stent neck. The present invention can simulate the actual motion of stent deployment and significantly shorten the simulation calculation time and efficacy evaluation time of simulated stent deployment within a vessel, thereby achieving real-time guidance during virtual aneurysm intervention.

The invention belongs to the technical field of biomedical materials and tissue engineering, and particularly relates to a self-pumping stent material with a double-layer heterogeneous structure as well as a preparation method and application of the self-pumping stent material. A hydrophobic membrane is prepared by an electrostatic spinning technology, and a hydrophilic microgel assembly is prepared by an emulsion method. Adding a dopamine modified polymer, and establishing a dynamic phenylboronic acid ester bond between microgel through a dopamine group to form a hydrophilic microgel assembly; the adhesion connection of the microgel assembly and the hydrophobic membrane is realized through mussel bionic chemical reaction of dopamine groups, and a double-layer heterogeneous structure based on the hydrophilic assembly and the hydrophobic membrane is constructed, so that a self-pumping effect is generated, and one-way flow of liquid components from the hydrophobic side of the stent to the hydrophilic side of the stent can be realized. Implanting the stent into an alveolar bone defect wherein the hydrophobic membrane contacts gingiva and the hydrophilic microgel assembly fills the bone defect; through the self-pumping effect of the stent, nutritional ingredients in the gingiva are unidirectionally pumped to the defect part of the alveolar bone, so that the regeneration of the alveolar bone is promoted.

The application relates to the technical field of medical devices, in particular to a stent, which comprises a main body structure, the main body structure comprises a plurality of annular structures and a plurality of connecting bridges, the annular structures are arranged in a rotationally symmetrical manner along the axial direction in a Z-shaped mode, the plurality of annular structures are connected to form the stent whole through the connecting bridges, and the lengths of the annular structures arranged in the Z-shaped mode are different. The annular structures are arranged in the rotationally symmetrical manner along the axial direction in the Z-shaped mode, the annular structures are connected to form the stent whole through the connecting bridges, the main body structure as a whole is deformed into a three-dimensional spiral type or an S-shaped mode, and the local part is not easy to stack, the problem that the stent cannot well adapt to the deformation of a blood vessel when the blood vessel is compressed and bent in the axial direction after the stent is implanted is solved, the stent and the blood vessel are synchronized in complex deformation (such as axial compression, bending and torsion), and therefore the mechanical stimulation to the blood vessel wall is reduced.

The present disclosure pertains to a stent that includes a proximal end and a distal end; and a plurality of interconnected and expandable rings positioned adjacent to one another from the proximal end to the distal end. Each ring is connected to and spaced apart from at least one adjacent ring through one or more connecting units. Additionally, the interconnected rings form a cavity. The rings at or near the proximal end include different diameters than the rings at or near the distal end. The present disclosure also pertains to methods of implanting a stent of the present disclosure in a blood vessel of a subject through the following steps: (1) positioning the stent at a desired location within the blood vessel; and (2) expanding the stent from a contracted configuration to an expanded configuration to secure the stent to the blood vessel wall.

The invention provides a stent for coronary artery opening lesion treatment, which belongs to the technical field of medical instruments and comprises a tubular stent main body and an anchoring structure, the anchoring structure is arranged at one end of the tubular stent body and comprises a plurality of petal-shaped unfolding units evenly distributed in the circumferential direction. The petal-shaped unfolding units are attached to the outer wall face of the tubular stent body in the compressed conveying state and automatically turn and unfold outwards in the in-vivo releasing state, and an anchoring face is formed, and the included angle between the anchoring face and the axis of the tubular stent body ranges from 80 degrees to 100 degrees. The end, close to the anchoring structure, of the tubular stent body is further provided with an axial moldable transition section, and the axial length of the moldable transition section ranges from 1.5 mm to 3 mm. The invention provides a coronary artery opening stent with a petal-shaped anchoring structure and an axial moldable transition section. The coronary artery opening stent aims at fundamentally solving the problems of precise positioning and reliable fitting of opening lesion stent implantation.

The invention provides a degradable drug-loading stent, the innovative design that a double-layer tubular body is combined with a novel drug-loading structure is adopted, the drug-loading structure comprises a plurality of first drug cavities formed in an inner layer and second drug cavities formed in an outer layer, corresponding to the first drug cavities in position and communicated with the first drug cavities, the first drug cavities penetrate through the inner layer in the radial direction of the stent, and the second drug cavities penetrate through the outer layer in the radial direction of the stent. The second medicine cavity is in a blind hole shape with an opening in the inner surface of the outer layer, the cavity spaces of the first medicine cavity and the second medicine cavity are unequal in size and are used for loading a medicine A and a medicine B respectively, and after the stent is implanted, the successive slow release effect that the medicine A and the medicine B in different parts are dissolved out is formed, so that classified and component placement and controllable release of various types of medicines are achieved, and the effect of slow release is achieved. The problems of single drug loading and uncontrollable drug release of a drug-loading stent in the prior art are effectively solved, different requirements of clinical complex environments can be met, and remarkable technical progress and application value are achieved.

The invention discloses a heart double stent capable of being released once, which comprises a main stent, and the lower end of the main stent is connected with a branch stent and a side stent; when the main support, the branch supports and the side supports are in a compressed state, the outer diameter of the branch supports is smaller than that of the main support. Through the ingenious design of double stents, especially the main stent, the branch stent and the side stent which are integrally connected with the main stent, and in cooperation with double-guide-wire conveying, conveying and releasing of the heart double stents of a main branch tube aiming at a main branch blood vessel and a side branch tube aiming at a side branch blood vessel can be achieved at a time; the possibility that the structure of the stent is damaged due to secondary conveying is avoided, and the success rate of a bifurcation lesion implantation double-stent operation is increased.

In exemplary examples, methods and systems for treating vascular disease by implanting a stent within the vasculature and using intravascular imaging to determine and ensure that the stent was property implanted and producing a desirable and effective results is disclosed herein. For example, a system may obtain optical shape sensing data and intravascular imaging data for a blood vessel. The system may process the optical shape sensing data and the intravascular imaging data to generate a three-dimensional model and image of the blood vessel immediately before and immediately after stent implantation into the blood vessel, and perform a precise comparison of the before and after images to ensure that the stent was properly implanted and will produce or is producing a desirable and effective result. The precise comparison may be based on a derived diameter associated with the location at which the stent is placed in the blood vessel based on the generated pre and post generated three-dimensional models.

The invention provides an aneurysm embolism auxiliary device, and belongs to the technical field of medical instruments. The device comprises a conveying catheter, an operating handle, a balloon and a filling unit, wherein the conveying catheter is used for conveying a treatment instrument to an aneurysm position; the operating handle is arranged at the near end of the conveying catheter; the balloon is arranged at the far end of the conveying catheter and is used for supporting a blood vessel after being filled; the filling unit is used for filling injection gel for treating the aneurysm into the aneurysm along the conveying catheter from the position of the operating handle, and the injection gel is used for being solidified in the aneurysm; during working, the conveying catheter conveys the balloon to the aneurysm position, the balloon supports a blood vessel for positioning after being filled, the filling unit fills injection gel into the aneurysm, and the injection gel is solidified and formed after entering the aneurysm so as to treat the aneurysm; the technical problems that in an existing aneurysm interventional therapy mode, a spring ring is prone to displacement, and bleeding risk is increased due to long-term medicine taking after stent implantation are mainly solved.

This invention provides an aneurysm embolization auxiliary device, belonging to the field of medical device technology. The device includes a delivery catheter, an operating handle, a balloon, and a filling unit. The delivery catheter delivers a treatment device to the aneurysm location. The operating handle is located at the proximal end of the delivery catheter. The balloon, after inflation, supports the blood vessel. The filling unit fills the aneurysm with an injectable gel for treating the aneurysm from the operating handle location along the delivery catheter. The injectable gel solidifies within the aneurysm. During operation, the delivery catheter delivers the balloon to the aneurysm location. After inflation, the balloon supports and positions the blood vessel. The filling unit fills the aneurysm with the injectable gel, which solidifies upon entering the aneurysm to treat it. This invention primarily addresses technical problems in existing interventional aneurysm treatment methods, such as easy displacement of coils and the increased risk of bleeding due to the need for long-term medication after stent implantation.

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

The invention discloses a magnetic control electric three-layer composite nerve scaffold for nerve regeneration microenvironment stage adaptation and a preparation method thereof. The outer layer of the stent is a PLLA-IAA membrane responding to inflammation microenvironment stimulation, the middle of the stent is an SPIONs-doped piezoelectric layer, and the inner layer of the stent is an Nrg-1-loaded neurotrophic factor sustained release layer. In the initial stage of stent implantation, reactive oxygen species (ROS) stimulates a responsive chain segment to break, and IAA is quickly released to inhibit an inflammatory microenvironment; then, an alternating magnetic field is applied to cause vibration of the SPIONs, formation of an electric signal in the piezoelectric layer is triggered, and a favorable electrophysiological microenvironment is provided for promoting neuronal differentiation and axon regeneration; under the action of environmental degradation, the spinning membrane structure disintegrates slowly and continuously releases the neurotrophic factor Nrg-1 so as to promote myelin sheath formation. The stent innovatively integrates the requirements of three stages of a nerve regeneration microenvironment, and realizes accurate, dynamic and multi-dimensional regulation and control of high-efficiency regeneration.

This invention relates to the technical field of medical devices, and more particularly to an implant delivery system. The implant delivery system includes an implant and a delivery device. The implant includes a first tubular member and a second tubular member, the distal portion of which is housed within the first tubular member such that the outer wall of the second tubular member engages with the inner wall of the first tubular member to form an openable or closable channel. The delivery device includes a sheath core, an outer sheath, and a restraint assembly. The compressed implant is housed within the outer sheath, which is slidable relative to the sheath core to release the implant. The restraint assembly is connected to the second tubular member and is used to detachably restrain the distal end of the second tubular member into a compressed state to open the channel when the first tubular member is in a radially extended state. In this implant delivery system, the channel can be fully opened under the action of the delivery device, thereby facilitating the establishment of a branch stent implantation path.