80 results about "Stent implantation" patented technology

A method of providing embolic protection for carotid stent implantation includes advancing an arterial sheath into an arterial system of a patient and advancing a venous sheath into a venous system of the patient. A fluid connection may be established between the venous sheath and the arterial sheath to enable retrograde flow of blood through the arterial sheath. The artery sheath may be advanced through the vasculature into the patient's carotid artery and the inflatable balloon may be inflated within the patient's carotid artery to block smooth blood flow therein. An interventional tool may be advanced through the interior lumen of the arterial sheath, the interventional tool sized such that a portion of the cross-sectional area of the interior lumen of the arterial sheath remains open for retrograde flow of blood.

The invention discloses a negative Poisson's ratio stent structure for heart and cerebral vessels and an optimization method of the negative Poisson's ratio stent structure, belongs to the technical field of medical instruments, and solves the problems of axial shortening, contradiction between radial supporting force and flexibility and low calculation efficiency in an optimization process of a traditional vascular stent due to a positive Poisson's ratio effect. Wherein a bracket structure of a curved-edge concave hexagonal geometric unit is adopted, and the bracket synchronously extends in the axial direction to present a negative Poisson's ratio effect when being subjected to an expansion load in the radial direction; degradable macromolecules or degradable metals are selected as the material of the stent; according to the optimization method, candidate design is generated through parametric modeling, performance indexes are obtained through finite element simulation, a neural network agent model is trained to predict multi-target performance, a Pareto optimal solution set is obtained through optimization by adopting a multi-target optimization algorithm, and manufacturing parameters are determined through finite element review. According to the invention, the implantation precision and the positioning accuracy of the stent are improved, the mechanical property and the biocompatibility are optimized, and the design efficiency is improved.

In an exemplary example, methods and systems are disclosed herein for treating vascular disease by implanting a stent within a vessel and using intravascular imaging to determine and ensure that the stent is properly implanted and produces the desired and effective results. For example, a system can obtain optical shape sensing data and intravascular imaging data of a vessel. The system can process the optical shape sensing data and the intravascular imaging data to generate three-dimensional models and images of the vessel immediately before and after the stent is implanted in the vessel and make an exact comparison of the before and after images to ensure that the stent is properly implanted and will produce or is producing the desired and effective results. The exact comparison can be based on a derived diameter associated with the location of the stent placement in the vessel, which is based on the generated pre- and post- three-dimensional models.

This application provides a stent placement device for cardiac surgery, comprising a cannula with an inlet end and an outlet end; the cannula is divided into 2-3 cannula branches at the inlet end; the cannula accommodates 2-3 stent delivery catheters; one stent delivery catheter is inserted from each cannula branch; all stent delivery catheters exit from the cannula outlet end; each stent delivery catheter has a guidewire lumen and a stent balloon pressure chamber; a guidewire is disposed in the guidewire lumen; a stent implanter is disposed at the tip of the stent delivery catheter, and an ultrasound positioning ball is sequentially disposed at the tip of the stent delivery catheter. This application utilizes a structure consisting of a flexible cannula and multiple stent delivery catheters to conveniently and simultaneously provide precise stent implantation for multiple blood vessels; by incorporating an ultrasound positioning ball with a corner reflector to enhance ultrasound reflection, the implantation and detailed operation of the device can be more easily completed under ultrasound monitoring.

A delivery device (10), which is used for delivering a stent implant (2) in a catheter (3) and comprises a delivery guidewire (1) and a pushing element (12). The delivery guidewire (1) comprises a stent compression section (11) for loading the stent implant (2), and a proximal portion of the delivery guidewire (1) connected to the proximal end of the stent compression section (11). The pushing element (12) at least comprises a distal-end pushing element (121). The distal-end pushing element (121) is fixed on the stent compression section (11) and is arranged at a position other than the proximal end of the stent compression section (11). When the delivery device (10) delivers the stent implant (2) in the catheter (3) to the distal end, the distal-end pushing element (121) pulls the stent implant (2) distally so as to push same, so that the stent implant (2) is in an axially pulled state. Therefore, such a configuration converts the mode of pressing the stent implant (2) to push same into the mode of pulling the stent implant (2) to push same, thereby avoiding the problem of increased pushing resistance caused by increased radial support force of the stent implant (2) itself during the delivery, and further reducing the risk and difficulty of delivery.

The present invention is entitled "Thrombectomy and Stent Implantation System". The present invention provides a design capable of both mechanical thrombectomy and stent implantation for the treatment of occlusions in the cerebral vasculature, which provides a three-catheter setup. A first outer catheter has the largest diameter and can serve as a guide catheter, while also serving as a sheath for the other catheters. A second deployment catheter can be configured for aspiration of the occlusion and can include a proximal stepped or recessed segment at the distal tip that can act as a housing for a woven expandable stent. The outer diameter of the stepped segment can be lined with an inflation device having a woven stent disposed on its top. Inside the second deployment catheter is a microcatheter that can deliver a mechanical thrombectomy device to the target site to retrieve the occlusion in the vessel, after which the stent can be expanded and implanted in the vessel.

A system and method for transesophageal echocardiogram-guided implantation of a stent are disclosed. The system includes at least a transesophageal echocardiogram (TEE) system, at least a display and at least a computing device configured to receive a plurality of ultrasound images, generate at least a three-dimensional (3D) cardiac model as a function of the plurality of ultrasound images, receive at least a 3D stent model, determine a view label for each of the plurality of ultrasound images and display the at least a 3D cardiac model and the at least a 3D stent model as a function of the view label.

This invention discloses a dynamic prediction system for long-term adverse cardiovascular event risk after stent implantation, belonging to the field of personal health risk assessment technology. It includes: a cardiovascular assessment module for determining the target cardiovascular adverse event presentation coefficient based on the target patient's first chest pain rating and real-time heart rate after stent implantation; a cardiac function assessment module for determining the emphasis of cardiac function analysis at each stage based on the target patient's physical examination data after stent implantation; a probability determination module for determining the probability of the first adverse event based on the target cardiovascular adverse event presentation coefficient and the emphasis of each cardiac function analysis; and an indicator determination module for comparing the target patient's first adverse event probability with the second adverse event probability of each monitored patient to obtain the target cardiovascular risk warning indicator for the target patient. This invention can improve the accuracy of long-term risk prediction for adverse cardiovascular events.

The invention belongs to the technical field of biomedical materials and tissue engineering, and particularly relates to a self-pumping stent material with a double-layer heterogeneous structure as well as a preparation method and application of the self-pumping stent material. A hydrophobic membrane is prepared by an electrostatic spinning technology, and a hydrophilic microgel assembly is prepared by an emulsion method. Adding a dopamine modified polymer, and establishing a dynamic phenylboronic acid ester bond between microgel through a dopamine group to form a hydrophilic microgel assembly; the adhesion connection of the microgel assembly and the hydrophobic membrane is realized through mussel bionic chemical reaction of dopamine groups, and a double-layer heterogeneous structure based on the hydrophilic assembly and the hydrophobic membrane is constructed, so that a self-pumping effect is generated, and one-way flow of liquid components from the hydrophobic side of the stent to the hydrophilic side of the stent can be realized. Implanting the stent into an alveolar bone defect wherein the hydrophobic membrane contacts gingiva and the hydrophilic microgel assembly fills the bone defect; through the self-pumping effect of the stent, nutritional ingredients in the gingiva are unidirectionally pumped to the defect part of the alveolar bone, so that the regeneration of the alveolar bone is promoted.

The application relates to the technical field of medical devices, in particular to a stent, which comprises a main body structure, the main body structure comprises a plurality of annular structures and a plurality of connecting bridges, the annular structures are arranged in a rotationally symmetrical manner along the axial direction in a Z-shaped mode, the plurality of annular structures are connected to form the stent whole through the connecting bridges, and the lengths of the annular structures arranged in the Z-shaped mode are different. The annular structures are arranged in the rotationally symmetrical manner along the axial direction in the Z-shaped mode, the annular structures are connected to form the stent whole through the connecting bridges, the main body structure as a whole is deformed into a three-dimensional spiral type or an S-shaped mode, and the local part is not easy to stack, the problem that the stent cannot well adapt to the deformation of a blood vessel when the blood vessel is compressed and bent in the axial direction after the stent is implanted is solved, the stent and the blood vessel are synchronized in complex deformation (such as axial compression, bending and torsion), and therefore the mechanical stimulation to the blood vessel wall is reduced.

The invention provides a stent for coronary artery opening lesion treatment, which belongs to the technical field of medical instruments and comprises a tubular stent main body and an anchoring structure, the anchoring structure is arranged at one end of the tubular stent body and comprises a plurality of petal-shaped unfolding units evenly distributed in the circumferential direction. The petal-shaped unfolding units are attached to the outer wall face of the tubular stent body in the compressed conveying state and automatically turn and unfold outwards in the in-vivo releasing state, and an anchoring face is formed, and the included angle between the anchoring face and the axis of the tubular stent body ranges from 80 degrees to 100 degrees. The end, close to the anchoring structure, of the tubular stent body is further provided with an axial moldable transition section, and the axial length of the moldable transition section ranges from 1.5 mm to 3 mm. The invention provides a coronary artery opening stent with a petal-shaped anchoring structure and an axial moldable transition section. The coronary artery opening stent aims at fundamentally solving the problems of precise positioning and reliable fitting of opening lesion stent implantation.

The invention provides a degradable drug-loading stent, the innovative design that a double-layer tubular body is combined with a novel drug-loading structure is adopted, the drug-loading structure comprises a plurality of first drug cavities formed in an inner layer and second drug cavities formed in an outer layer, corresponding to the first drug cavities in position and communicated with the first drug cavities, the first drug cavities penetrate through the inner layer in the radial direction of the stent, and the second drug cavities penetrate through the outer layer in the radial direction of the stent. The second medicine cavity is in a blind hole shape with an opening in the inner surface of the outer layer, the cavity spaces of the first medicine cavity and the second medicine cavity are unequal in size and are used for loading a medicine A and a medicine B respectively, and after the stent is implanted, the successive slow release effect that the medicine A and the medicine B in different parts are dissolved out is formed, so that classified and component placement and controllable release of various types of medicines are achieved, and the effect of slow release is achieved. The problems of single drug loading and uncontrollable drug release of a drug-loading stent in the prior art are effectively solved, different requirements of clinical complex environments can be met, and remarkable technical progress and application value are achieved.

In exemplary examples, methods and systems for treating vascular disease by implanting a stent within the vasculature and using intravascular imaging to determine and ensure that the stent was property implanted and producing a desirable and effective results is disclosed herein. For example, a system may obtain optical shape sensing data and intravascular imaging data for a blood vessel. The system may process the optical shape sensing data and the intravascular imaging data to generate a three-dimensional model and image of the blood vessel immediately before and immediately after stent implantation into the blood vessel, and perform a precise comparison of the before and after images to ensure that the stent was properly implanted and will produce or is producing a desirable and effective result. The precise comparison may be based on a derived diameter associated with the location at which the stent is placed in the blood vessel based on the generated pre and post generated three-dimensional models.

This invention provides an aneurysm embolization auxiliary device, belonging to the field of medical device technology. The device includes a delivery catheter, an operating handle, a balloon, and a filling unit. The delivery catheter delivers a treatment device to the aneurysm location. The operating handle is located at the proximal end of the delivery catheter. The balloon, after inflation, supports the blood vessel. The filling unit fills the aneurysm with an injectable gel for treating the aneurysm from the operating handle location along the delivery catheter. The injectable gel solidifies within the aneurysm. During operation, the delivery catheter delivers the balloon to the aneurysm location. After inflation, the balloon supports and positions the blood vessel. The filling unit fills the aneurysm with the injectable gel, which solidifies upon entering the aneurysm to treat it. This invention primarily addresses technical problems in existing interventional aneurysm treatment methods, such as easy displacement of coils and the increased risk of bleeding due to the need for long-term medication after stent implantation.

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

The invention discloses a magnetic control electric three-layer composite nerve scaffold for nerve regeneration microenvironment stage adaptation and a preparation method thereof. The outer layer of the stent is a PLLA-IAA membrane responding to inflammation microenvironment stimulation, the middle of the stent is an SPIONs-doped piezoelectric layer, and the inner layer of the stent is an Nrg-1-loaded neurotrophic factor sustained release layer. In the initial stage of stent implantation, reactive oxygen species (ROS) stimulates a responsive chain segment to break, and IAA is quickly released to inhibit an inflammatory microenvironment; then, an alternating magnetic field is applied to cause vibration of the SPIONs, formation of an electric signal in the piezoelectric layer is triggered, and a favorable electrophysiological microenvironment is provided for promoting neuronal differentiation and axon regeneration; under the action of environmental degradation, the spinning membrane structure disintegrates slowly and continuously releases the neurotrophic factor Nrg-1 so as to promote myelin sheath formation. The stent innovatively integrates the requirements of three stages of a nerve regeneration microenvironment, and realizes accurate, dynamic and multi-dimensional regulation and control of high-efficiency regeneration.

This invention relates to the technical field of medical devices, and more particularly to an implant delivery system. The implant delivery system includes an implant and a delivery device. The implant includes a first tubular member and a second tubular member, the distal portion of which is housed within the first tubular member such that the outer wall of the second tubular member engages with the inner wall of the first tubular member to form an openable or closable channel. The delivery device includes a sheath core, an outer sheath, and a restraint assembly. The compressed implant is housed within the outer sheath, which is slidable relative to the sheath core to release the implant. The restraint assembly is connected to the second tubular member and is used to detachably restrain the distal end of the second tubular member into a compressed state to open the channel when the first tubular member is in a radially extended state. In this implant delivery system, the channel can be fully opened under the action of the delivery device, thereby facilitating the establishment of a branch stent implantation path.

The present invention is directed to the use of cangrelor for the treatment and / or prevention of shunt thrombosis in patients suffering congenital heart diseases undergoing shunt surgery. The invention is also directed to the use of cangrelor for the treatment and / or prevention of stent thrombosis in pediatric patients undergoing stent implantation.

A system includes a processor circuit in communication with an extraluminal imaging device and an intraluminal imaging device. The processor circuit obtains an enhanced stent deployment extraluminal image and a plurality of intraluminal images. The enhanced stent deployment extraluminal image and the each of the plurality of intraluminal images are associated with locations along a pathway. The pathway is overlaid over an extraluminal image. Based on the locations of the pathway, the processor circuit coregisters the plurality of intraluminal images to the enhanced stent deployment extraluminal image and outputs a screen display of one of the plurality of intraluminal images and the enhanced stent deployment extraluminal image with an indicator identifying the location at which the displayed intraluminal image was obtained. The processor circuit may also determine an expansion score for intraluminal images depicting the stent and identify regions of the stent corresponding to an expansions score below a threshold.

The invention discloses a medical drug-loading paranasal sinus stent as well as a preparation method and application thereof. The medical drug-loaded paranasal sinus stent comprises a nasosinusitis treatment drug and medical catalyst-free polycaprolactone loaded with the nasosinusitis treatment drug, the drug loading capacity of the medical drug-loading paranasal sinus stent is 2 to 20 weight percent; the 24-hour burst release rate of the medical drug-loading paranasal sinus stent is lt; the continuous release time is more than or equal to 4 weeks; wherein the medical catalyst-free polycaprolactone is prepared by carrying out ring opening polymerization on double ether bond oxalic acid amide dihydric alcohol serving as an initiator and caprolactone. According to the medical drug-loaded paranasal sinus stent, the risk of catalyst residue is completely eradicated from the source, the stent implantation safety is guaranteed, the controllable degradation performance and the drug slow release effect of the stent can meet the paranasal sinus postoperative repair requirement, and the medical drug-loaded paranasal sinus stent is suitable for in-vivo implantation and supporting of people or animals and has important prospects in the field of chronic nasosinusitis postoperative treatment.

Delivery systems for expandable and stented implants include tensioning members that are attached to rotors with hook-like attachment projections are wound onto the shaft of the delivery system, which is then rotated to unwind the tensioning members and incrementally expand the implant.

The application discloses a method for removing endotoxin from gelatin. The method comprises the following steps: (1) adding pyrogen-free water to gelatin raw materials, swelling, and then heating to 50-70 DEG C to prepare a gelatin solution with a mass concentration of 3-20%; (2) adding an adsorbent with a mass of 2.5%-100% of the gelatin, adsorbing at 40-70 DEG C for 30-240 min, and then separating the adsorbent from the gelatin solution by filtration or centrifugal separation to obtain a filtrate; (3) further filtering the filtrate by filter paper and thin-layer diatomite to obtain a refined filtrate, diluting the refined filtrate with 4 times the volume of water, ultrafiltering by using a membrane with a molecular weight cut-off of 5000-20000 Da, finally concentrating to a concentration of 10-25%, sterilizing, and drying to obtain gelatin solid with low endotoxin; the adsorbent used in step (2) is an adsorbent with a silica gel carrier, polyethylene imine as a ligand, and a spacer arm grafted or ungrafted, and the spacer arm is hexanediamine. The purified gelatin can be used in the preparation of blood plasma substitutes, tissue engineering scaffolds, implants and absorbable hemostatic materials.

The application provides a supramesenteric artery special stent, which comprises a plurality of single-layer meshes; the plurality of single-layer meshes are sequentially connected to form a tubular stent, and the tubular stent has a certain bending curvature; the head section and the tail section of the tubular stent are of the same mesh structure; and the single-layer meshes of the middle section of the tubular stent are connected through a plurality of connecting pieces, so that the bending curvature of the middle section of the tubular stent can be adjusted. In the application, the plurality of single-layer meshes are sequentially connected to form a tubular stent which itself has a movable bending curvature; then, according to the bending curvature of the supramesenteric artery, the bending curvature of the middle section of the tubular stent is adjusted through the connecting pieces, so as to adapt to the bending stroke of the supramesenteric artery; then, the stent is implanted into the lesion position of the supramesenteric artery, and cooperates with the supramesenteric artery, so that the stent can better adhere to the supramesenteric artery, and the supporting effect of the supramesenteric artery is improved.

This invention relates to a stent delivery system and a stent system including the same. The stent delivery system includes a force transmission network centered at a pivot point at its distal end, used to decompose the force applied at the pivot point along the network. The force transmission network converges at its distal end near the pivot point to form a distal center. When radially restrained, the force transmission direction of the network is closer to the axial direction and towards the proximal end. When no external force restraint is applied, the force transmission network deforms, causing the force transmission direction to deviate further from the axial direction and towards the proximal end. By incorporating force transmission components, the stent delivery system effectively decomposes the force generated when the distal end of the delivery system contacts the vessel wall during stent implantation. Furthermore, the deformation of the force transmission network further offsets some or all of the decomposed force, thereby significantly reducing the force exerted by the stent delivery system on the vessel wall during stent implantation and reducing the risk of vessel wall puncture.

The invention relates to the field of medical instruments, in particular to a nano diamond-like film intravascular stent and a preparation method thereof.The preparation method comprises the following steps that firstly, a base material is pretreated, then the nano diamond-like film stent is prepared through a plasma enhanced chemical vapor deposition technology, and after an equipment reaction chamber is adjusted to be in a vacuum state, the nano diamond-like film intravascular stent is prepared under argon protection; the method comprises the following steps: inputting benzene into a vacuum reaction chamber of direct-current arc discharge plasma, introducing silane gas at the same time, bombarding the generated plasma to a negative voltage cathode, and forming a diamond-like carbon film containing a silicon element on the surface when the plasma passes through a substrate material support sample, the silicon element content in the diamond-like carbon film being 15-45%; the silicon element is mainly added to form the elastic concentration gradient type diamond-like carbon film stent, so that the adhesive force, toughness, tensile strength and other physical properties of the coating are improved, the stent has good biocompatibility, and later thrombosis and restenosis after stent implantation are avoided.

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

The present application provides a kind of film covered stent, including main body support and limiting structure, main body support is equipped with recess;Limiting structure includes limiting piece and constraint piece, limiting piece is detachably connected with constraint piece;When film covered stent is in first state, limiting piece can be used for limiting the target section of sheath core in radial direction under the constraint of constraint piece, target section is an axial section of sheath core, target section is in the axial region between the proximal end and the distal end of recess in first state;When film covered stent is in second state, constraint piece can be separated from limiting piece, so that limiting piece removes the restriction to target section.The film covered stent provided by the embodiment of the present application can more accurately align the recess of the film covered stent to the branch blood vessel after implantation, reduce the probability of the film covered stent blocking or blocking the branch blood vessel, and thus ensure that the blood flow of the branch blood vessel can flow normally and smoothly, reduce the complications caused by blood incontinence.

This invention relates to the field of medical device technology, and mainly provides a peripheral adaptive guiding protection structure for implantation of artificial heart valve stents. It includes a core tube, an inner sheath, an outer sheath, a capsule assembly body, an external adaptive folding structure, and a self-expanding valve stent. The capsule assembly body includes a capsule cavity movably inserted through the core tube, the capsule cavity having a release opening, a self-expanding valve stent folded within the capsule cavity, an external adaptive folding structure fixedly disposed on the outer wall of the capsule cavity, an outer sheath movably sleeved on the core tube, and an inner sheath movably inserted within the outer sheath. The external adaptive folding structure is configured to have a retracted state folded and attached between the capsule cavity and the outer sheath, and an unfolded state that expands radially outward along the capsule cavity and forms a ring surrounding the capsule cavity and the outside of the release opening. This invention solves the technical problem of low surgical success rate caused by structural defects in existing self-expanding valve stents during release.

1. The name of the design product: Shockwave balloon main machine. 2. The use of the design product: used for adult patients to pretreat and balloon dilate the calcified lesions of the primary coronary artery before stent implantation. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective drawing.

The invention discloses a spiral cutting microcatheter for coronary angulation calcification lesion, which comprises a catheter main body and cutting blades, a multi-head spiral groove is arranged on the peripheral surface of the middle section of the catheter main body, and a plurality of cutting blades are embedded in each spiral groove at intervals along the extension direction of the spiral groove. The length direction of each cutting blade is roughly consistent with the thread direction of the position where the cutting blade is located, the top end of each cutting blade does not exceed the peripheral face of the catheter where the cutting blade is located, the passing ability is improved through a spiral structure, and the cutting blades are used for cutting calcified plaques. Compared with a common micro-catheter, the spiral cutting micro-catheter has a longer thread lead, a thicker outer diameter and a deeper spiral groove, and by means of the spiral structure, the micro-catheter can rotate through a calcification angulation lesion. Meanwhile, the blade is embedded in the spiral groove, the calcification lesion can be cut, the calcification lesion can be effectively expanded, and passing of subsequent instruments and stent implantation are facilitated.