149 results about "Vascular stent" patented technology

The invention discloses a rigidity self-adaptive intravascular stent based on a three-dimensional virtual woven structure and a control method thereof. The method comprises the steps of reconstructing a preoperative tumor blood vessel three-dimensional model based on clinical iconography data, constructing a stent initialization model, starting a hexagonal knitting three-dimensional virtual algorithm, performing intravascular stent knitting modeling, realizing structural parameter optimization and adaptive stent expansion in combination with preoperative image data of a patient, and completing personalized deployment. The wire winding angle and the mesh density of each area of the stent are adjustable, the stent is adaptive to the complex intracranial aneurysm blood vessel form, accurate fitting and risk guiding are achieved, the treatment effect is improved, the postoperative complication risk is reduced, and the stent has good engineering suitability and clinical application prospects.

The invention provides a recoverable intravascular stent, and belongs to the technical field of interventional therapy instruments. The stent comprises a first stent body, a second stent body and an isolation component, and the outer side wall of the first stent body is used for directly supporting a blood vessel and can automatically contract in the radial direction; the second stent is coaxially arranged on the inner side of the first stent and used for supporting radial expansion of the first stent; the isolation part is arranged on the first bracket and / or the second bracket and is used for reducing the friction force between the first bracket and the second bracket; when the stent is taken out, the second stent is gradually taken out from the inner side of the first stent, the first stent automatically and radially contracts in the process of losing the support of the second stent to reduce the embedding force with the side wall of the blood vessel, and the whole stent is conveniently taken out; the intravascular stent is mainly used for solving the technical problems that in the prior art, the intravascular stent is large in resistance and not easy to take out.

The invention discloses an intravascular stent bending torsion fatigue test device, and belongs to the technical field of fatigue test machinery. The intravascular stent bending torsional fatigue test device comprises a rack, the rack comprises a door-shaped support, a back plate and a base, the door-shaped support is provided with a bending load module, the bending load module comprises a first stepping motor, the output end of the first stepping motor penetrates through the back plate and is fixedly connected with an eccentric wheel through an extension shaft, and a pair of sliding blocks is additionally arranged; a sliding rail is arranged on the inner side of the door-shaped support, the sliding blocks are arranged on the sliding rail, a cantilever is connected between the pair of sliding blocks, the top of the cantilever is connected with the lower side of the top of the door-shaped support through a spring, a plurality of first loading connectors are arranged on the front face of the cantilever, and a torsion module is additionally arranged. The fatigue durability under bending-torsion dual loads can be tested, and the fatigue performance of the stent under the condition of blood vessel deformation during limb movement can be truly simulated.

The application provides an absorbable vascular stent covering facilitating endothelialization and a preparation method thereof, and belongs to the technical fields of biomedical materials and vascular stent covering preparation. The absorbable vascular stent covering facilitating endothelialization is prepared based on modified silk fibroin and domestic silkworm silk. The inner surface of the absorbable vascular stent covering facilitating endothelialization has a nano topological structure and a matrix-like component simulating a vascular basement membrane, and the outer surface has a micro topological structure. The absorbable vascular stent covering facilitating endothelialization has good mechanical properties and excellent endothelial cell activity, and can be used for producing a vascular stent capable of rapidly forming a new endothelial layer, maintaining stable blood flow, and inhibiting thrombosis and inflammation.

The application relates to a loading device for assisting stent sheathing and a manufacturing method thereof, which is used for sleeving on a sheath tube and comprises a first protection section with a cylindrical lumen and a protection section inner diameter D4, a second protection section with a conical lumen and connected with the first protection section at a large end side, and a loading guide section with a conical lumen and connected with the small end side of the second protection section at a second stage; the protection section inner diameter D4 is larger than the maximum outer diameter D1 of the sheath tube, and the minimum diameter D5 of the second stage is smaller than the minimum inner diameter D2 of the sheath tube. The loading device can assist the vascular stent to enter the inner cavity of the sheath tube, reduces the difficulty of stent sheathing, reduces the labor of doctors, and improves the success rate of surgery.

This invention relates to a cardiovascular stent loading sheath and a retraction system for an advancing stent sheath. The cardiovascular stent loading sheath, through the deformation-sealing opening of a deformable element disposed on the sheath tube, achieves the purpose of sealing the sheath opening after stent deployment. This ensures that when the loading sheath retracts across the stent, the sheath end opening does not snag on the stent, effectively preventing stent displacement and reducing surgical risks.

The application provides a recyclable vascular stent, and belongs to the technical field of interventional treatment instruments; the stent comprises a first stent, a second stent and a separation component; the outer side wall of the first stent is used for directly supporting a blood vessel and can automatically contract in a radial direction; the second stent is coaxially arranged on the inner side of the first stent and is used for supporting the first stent to expand in a radial direction; the separation component is arranged on the first stent and / or the second stent and is used for reducing the friction between the first stent and the second stent; when the stent is taken out, the second stent is gradually taken out from the inner side of the first stent, and the first stent automatically contracts in a radial direction in the process of losing the support of the second stent to reduce the embedding force with the side wall of the blood vessel, so that the taking out of the whole stent is facilitated; and the technical problem that the existing technology has a large resistance and is not easy to take out when the vascular stent is taken out is solved.

The invention discloses a negative Poisson's ratio stent structure for heart and cerebral vessels and an optimization method of the negative Poisson's ratio stent structure, belongs to the technical field of medical instruments, and solves the problems of axial shortening, contradiction between radial supporting force and flexibility and low calculation efficiency in an optimization process of a traditional vascular stent due to a positive Poisson's ratio effect. Wherein a bracket structure of a curved-edge concave hexagonal geometric unit is adopted, and the bracket synchronously extends in the axial direction to present a negative Poisson's ratio effect when being subjected to an expansion load in the radial direction; degradable macromolecules or degradable metals are selected as the material of the stent; according to the optimization method, candidate design is generated through parametric modeling, performance indexes are obtained through finite element simulation, a neural network agent model is trained to predict multi-target performance, a Pareto optimal solution set is obtained through optimization by adopting a multi-target optimization algorithm, and manufacturing parameters are determined through finite element review. According to the invention, the implantation precision and the positioning accuracy of the stent are improved, the mechanical property and the biocompatibility are optimized, and the design efficiency is improved.

The present invention relates to the field of medical device technology, and in particular, to a vascular stent, a vascular stent system, and a method for preparing same. The method comprises: dissolving a degradable water-insoluble polymer in a solvent to prepare a first spinning solution, dissolving a degradable water-soluble polymer in a solvent to prepare a second spinning solution, connecting the first spinning solution and the second spinning solution to an electrospinning device, and performing electrostatic spinning to form a vascular stent. In the described preparation process, the degradable water-insoluble polymer and the degradable water-soluble polymer are subjected to a spinning process for vascular stent processing. When the vascular stent is delivered and expanded in vivo, a degradable water-soluble polymer part of the fiber filament is dissolved in the body fluid, thereby enhancing the slippage capability between fibers and improving the expansion and over-expansion performance of the stent.

The present invention discloses a bioresorbable cardiovascular stent (100). The bioresorbable cardiovascular stent (100) comprising at least one strut (104) (110) connecting the plurality of rhombus-shaped cells (102) in both the longitudinal directions and the circumferential directions and each strut (104) (110) provided with a consistent thickness (108) and width (106). The stent (100) maintains a uniform thickness (108) throughout its length, and featuring struts (104, 110) with consistent thickness (108). The stent (100) is manufactured by using a micro-injection molding process with a single sprue-less hot runner gate. The bioresorbable cardiovascular stent (100) is configured to maintain structural integrity, biocompatible properties, improve radial stiffness to (612 kPa / mm) and radial strength to (225 kPa).

The present application relates to a kind of transarticular vascular stents and its preparation method, transarticular vascular stent includes the first part and second part distributed along the axial direction of transarticular vascular stent;First part includes multiple first stent rings spaced apart along the axial direction of transarticular vascular stent and independent of each other and the whole surface film fixedly arranged on multiple first stent rings;Wherein, from proximal end to distal end, the distance between adjacent two first stent rings gradually increases;Second part includes multiple second stent rings spaced apart along the axial direction of transarticular vascular stent and independent of each other and multiple rows of connecting film groups sequentially arranged along the axial direction of transarticular vascular stent;Each row of connecting film groups includes multiple connecting membranes uniformly distributed along the circumferential direction of transarticular vascular stent, and both ends of each connecting membrane are respectively fixedly connected with adjacent two second stent rings;The width of the rod forming first stent ring is greater than the width of the rod forming second stent ring.

The invention discloses an intravascular stent coating as well as a preparation method and application thereof, and belongs to the technical field of biological materials. The intravascular stent coating is obtained by reaction of a porous coating and an anion solution containing drug molecules, the porous coating contains micro-nano albumin-polypeptide particles stacked on the surface of a stent matrix, and the micro-nano albumin-polypeptide particles are formed by co-assembly of albumin and polypeptide containing hydrophobic amino acid under induction of an oxidizing agent; the porosity of the intravascular stent coating is smaller than that of the porous coating. The intravascular stent coating has excellent biocompatibility and can achieve high loading of drugs, along with degradation of the intravascular stent coating, the released polypeptide and drugs can play dual effects, and the degradation process is beneficial to prolonging the treatment effect of the intravascular stent. The intravascular stent with the intravascular stent coating can reduce or avoid inflammatory response and postoperative complications, and has high application value.

The utility model relates to the technical field of medical instruments, and provides a conveying system which comprises a shell, a finger wheel, a transmission mechanism, a catheter assembly and an intravascular stent. Part of the finger wheel and the transmission mechanism are arranged in the shell, the finger wheel is connected with the transmission mechanism, part of the catheter assembly extends out of the shell, the transmission mechanism is connected with the catheter assembly, and the catheter assembly is used for conveying an intravascular stent; when the finger wheel rotates, the transmission mechanism can be driven to act, and then the catheter assembly is driven to move to release the intravascular stent. The intravascular stent comprises a stent body, and the diameter of the stent body is gradually reduced or gradually reduced in the extension direction of the length of the stent body. According to the conveying system, the stent body is arranged to be in the hollow circular truncated cone shape or the stepped barrel shape, the conveying system can adapt to blood vessel physiological deformation with unequal diameters and taper, blood vessels can be effectively expanded and well attached to the wall, damage caused by excessive expansion to the blood vessels is avoided, and the treatment effect is guaranteed.

The invention relates to the technical field of medical instruments, in particular to an intravascular stent conveying system and a conveying method.The intravascular stent conveying system comprises an intravascular stent and a conveying device, and the intravascular stent comprises a telescopic tube, a main tube connected with the front end of the telescopic tube and a plurality of branch tubes connected to one side of the telescopic tube; the conveying device comprises a handle assembly, a main body bending adjusting assembly, a main body releasing assembly, a branch bending adjusting assembly, a branch releasing assembly and an outer sheath assembly. The handle assembly comprises a holding handle, a supporting rod and a guide head which are connected in sequence, and the holding handle is hollow; the outer sheath assembly is arranged on the periphery of the supporting rod in a sleeving mode and located between the holding handle and the guide head. The requirement for bending adjustment during intravascular stent implantation is met, independent release of all structures of the intravascular stent is achieved, the release mode is simple and convenient, the learning curve is short, profound hypothermia circulation arrest is avoided in the whole operation process, the operation difficulty is reduced, and damage to a patient is reduced.

The invention relates to a cardiovascular stent with a double-ultrasonic positioning function, which adopts an ultrasonic positioning principle to position plaques in blood vessels, and comprises a catheter assembly, a balloon component and a vascular stent, the balloon component is arranged at the far end of the catheter assembly, the vascular stent is arranged on the outer side of the balloon component, and the balloon component is arranged on the outer side of the balloon component through special design of a built-in catheter. The balloon catheter has an ultrasonic positioning and imaging function and a double-ultrasonic positioning function, the imaging function in coronary vessels can be achieved on the premise of reducing use of contrast agents and X-rays, accurate positioning of the balloon is achieved, accurate release of the stent is completed, the problem that part of patients are intolerant to the contrast agents is solved, and the balloon catheter has the advantages of being simple in structure and convenient to use. By optimizing the combination mode of the ultrasonic sensor and the intravascular stent, the accuracy and safety of the operation are improved, and a new solution is provided for percutaneous coronary intervention and treatment of cardiovascular diseases.

An intravascular device may have a first configuration during deployment and a second configuration after deployment. The first configuration has a first radial strength; and the second configuration has a second radial strength. The first radial strength is less than the second radial strength. A system may include an intravascular device; a wire extending through the intravascular device to expand or contract the intravascular device; a proximal hub coupled to the wire; a distal hub coupled to the wire; and a plurality of tethers extending from an input device and through the intravascular device. At least a portion of the plurality of tethers has electrical conductivity. Application of energy to the at least a portion of the plurality of tethers may disengage the plurality of tethers from the intravascular device and fuse a luminal segment of the plurality of tethers, extending through the intravascular device, to the intravascular device.

The utility model provides a kind of vascular stent, the device includes: first support, first support includes first support unit and first pipe body, first support unit is set on first pipe body, along the length direction of first pipe body extends, and stop and resist the outside wall of first pipe body, first pipe body is distributed with multiple first hollow holes of interval distribution;Second support, second support includes second support unit and second pipe body, second support unit is set on second pipe body, along the length direction of second pipe body extends, and stop and resist the outside wall of second pipe body, second pipe body is distributed with multiple second hollow holes of interval distribution;The end of second support is connected with first support, the lumen of first pipe body is communicated with the lumen of second pipe body.In the utility model, sufficient radial support force is provided while excellent flexibility is guaranteed, the mechanical stress stimulation to blood vessel intima is small, and the long-term patency of main branch and side branch is guaranteed.

The application discloses a multifunctional blood vessel stent with a negative Poisson's ratio structure and a preparation method thereof, relates to the technical field of medical devices, and comprises the construction of a blood vessel stent model with a negative Poisson's ratio structure, selective laser melting additive manufacturing, chemical polishing treatment and surface biomimetic modification treatment. The stent can better adapt to the deformation of a blood vessel by virtue of the negative Poisson's ratio characteristic, reduces incompatibility caused by different deformation steps, the structure of the stent is round and smooth, blood flow turbulence and vortex at sharp corners of a traditional stent can be effectively avoided, the hemodynamic performance is improved, the risk of platelet activation and thrombosis is reduced, a surface gradient coating is prepared, multi-mechanism synergy is realized, and the formation of an endothelial layer on the surface of the stent is facilitated.

The application discloses a controllable degradation high-corrosion-resistance medical magnesium-aluminum alloy blood vessel stent and a preparation method thereof. The method comprises the following steps: subjecting magnesium alloy ingots containing Al, Zn, Ca and Mn to homogenization treatment, hot extrusion, cold drawing and recrystallization annealing to obtain low-aluminum magnesium-aluminum alloy microtubular materials containing aluminum second-phase non-continuous discrete distribution; after laser cutting, deburring, electrochemical polishing and surface activation, an inner layer rich in MgF2 and an outer layer rich in calcium and phosphorus are sequentially constructed; a polydopamine interface anchoring layer is formed, and a degradable polymer sealing liquid containing a heparinized hyaluronic acid-REDV peptide composite active component is coated to form an active flexible sealing layer after solidification. The stent obtained by the application has good corrosion resistance, controllable degradation, mechanical support retention capacity and endothelial repair promotion performance.

The application discloses a peripheral biodegradable vascular stent with a partitioned reinforced structure, which is divided into at least one double-layer reinforced area and at least one single-layer flexible area along the axial direction; the double-layer reinforced area comprises an inner-layer tube stent and an outer-layer tube stent which are coaxially sleeved, and the tube walls of the inner-layer tube stent and the outer-layer tube stent are in a hollow mesh structure; the peripheral wall of the inner-layer tube stent is provided with a plurality of radially extending connecting holes, and the inner peripheral wall of the outer-layer tube stent is provided with a plurality of radially extending connecting columns which are in one-to-one correspondence with the connecting holes and are embeddedly connected; the single-layer flexible area is in a single-layer mesh structure and has the same configuration as the outer-layer tube stent; and a smooth gradient transition structure is arranged between the double-layer reinforced area and the single-layer flexible area. The application solves the problems of excessive reinforcement, sacrifice of flexibility, insufficient absolute supporting force of a single-layer structure and failure caused by different degradation steps of a multi-layer structure.

The present invention relates to the field of body membrane processing and manufacturing technology, and specifically to a high-precision processing method for a human blood vessel model, which specifically includes the following steps: obtaining original data of medical angiography blood vessels; drawing a parametric surface model of the inner wall of the blood vessel; designing and processing a cavity mold; designing and processing an outer frame mold; processing a perfusion mold; using a lost mold; designing and processing a blood vessel stent; surface treatment of the lost mold; coating of blood vessel silicone; finished product output; and assembly of a hollow silicone blood vessel with a pulsation device. In the technical solution of the present invention, the raw materials are easy to purchase and have low cost; the dissolution process can be unmanned and there is no environmental pollution problem; through the action of a rotary molding machine and a circulating water demoulding machine, the blood vessel wall thickness can be ensured to be uniform, large-volume blood vessel models can be formed in one piece, and the yield rate is high. Mass production can be achieved, and the blood vessel model pulsation data can be adjusted according to the human blood pressure values ​​during surgical robot development or preoperative simulation by medical personnel.

The utility model relates to the technical field of medical instruments, and discloses an intravascular stent structure capable of reducing pressure stress, the intravascular stent is of a tubular net rack structure and comprises a plurality of annular wave rods and stent connecting rods, the annular wave rods are arranged in the axial direction of the intravascular stent, a plurality of stent connecting rods are arranged on one side of each wave rod, and the stent connecting rods are arranged on the other side of each wave rod. One end of each support connecting rod is connected with an adjacent wave rod, the section of each wave rod is arranged in a wave shape, and the support is characterized in that no less than one group of pressure stress parts capable of reducing the pressure stress of the wave rods are arranged on the side surfaces of the wave rods; due to the design of the wave-shaped wave rods and the pressure stress part, the support has more elastic deformation space, when the support is stressed, the support can elastically deform to a certain degree at the fluctuation of waves and the bending part of the pressure stress part instead of directly bearing all the pressure like a rigid structure, and the elastic deformation absorbs part of the pressure, so that the stress resistance of the support is improved. Therefore, the pressure stress is reduced.

The present invention provides a composite vascular stent coating for regulating the growth activity of endothelial cells and a preparation method thereof; the composite vascular stent coating of the present invention uses silk nanofiber membranes as the inner and outer layers of the composite vascular stent coating, and adopts weaving technology to weave a seamless polyester tubular fabric as the core layer on the basis of the inner layer of the composite vascular stent coating; the composite vascular stent coating has a microstructure and matrix-like components that imitate the basement membrane of natural blood vessels, which is beneficial to the mechanical engagement between the outer surface of the coating and the inner side of the diseased blood vessel, stabilizes blood flow, avoids turbulence formation, and more significantly improves the adhesion, spreading, growth and proliferation ability of endothelial cells on its inner surface, quickly forms a new endothelial layer, inhibits the occurrence of thrombosis and inflammation, maintains long-term patency of the lumen, and has good application value.

An intravascular device may have a first configuration during deployment and a second configuration after deployment. The first configuration has a first radial strength; and the second configuration has a second radial strength. The first radial strength is less than the second radial strength. A system may include an intravascular device; a wire extending through the intravascular device to expand or contract the intravascular device; a proximal hub coupled to the wire; a distal hub coupled to the wire; and a plurality of tethers extending from an input device and through the intravascular device. At least a portion of the plurality of tethers has electrical conductivity. Application of energy to the at least a portion of the plurality of tethers may disengage the plurality of tethers from the intravascular device and fuse a luminal segment of the plurality of tethers, extending through the intravascular device, to the intravascular device.

A vascular shunt stent includes a main body tube and at least one branch tube axially inserted into an inner lumen of the main body tube. The main body tube includes a tubular main membrane. At least one branch tube includes a tubular branch membrane, which is accommodated in an inner lumen of the main membrane. A first sealing film is arranged between a distal end of the main membrane and a distal end of the branch membrane to separate the inner lumen of the main membrane into a main opening and at least one first sub-opening, the first sub-opening is in sealed connection with the distal end of the branch membrane. An included angle between a plane defined by the first sub-opening is not parallel with a plane defined by the main opening.

This invention relates to the field of vascular stent fabrication technology, and discloses a method for fabricating a stent with electrodes, comprising the following steps: providing a planar stent precursor with thermally responsive deformation characteristics; forming a conductive layer on the surface of the planar precursor, and patterning the conductive layer to form at least one electrode unit and at least one conductive wire unit electrically connected to the electrode unit; forming a non-conductive material layer on at least a portion of the surface of the conductive layer; placing the planar precursor under constraint and heating it to a molding temperature below 300°C to soften the planar precursor, cause a shape memory phase transition or crystal structure transformation, and shape it into a stent structure using a mold; wherein, the non-conductive material layer maintains structural integrity and insulation properties at the molding temperature, the non-conductive material layer has windows for exposing the electrode unit, and the non-conductive material layer covers the conductive wire unit, thus avoiding thermal damage to the non-conductive material layer caused by high-temperature processes.

An aortic arch brachial artery vascular stent belongs to medical consumables and is a covered stent, including a main stent and two branch stents. One end of the two branch stents is embedded in the front end of the main stent. The front end of the main stent is provided as a connector connected to the branch stent. One end of the connector is an integrated structure with the main stent, and the other end is closed and provided with a skirt extending outward. Two through holes arranged in parallel are provided in the skirt. One end of the branch stent is a connecting end, which passes through the through hole of the skirt and goes deep into the connecting end of the main stent. A limiting structure is provided at the connecting end of the branch stent. The present invention is novel in concept and ingenious in design. When applied to the innominate artery of the aortic arch, it can effectively reduce the difficulty of surgical placement of the covered stent, shorten the operation time, and improve the success rate.

The utility model discloses a cutting tool for a cardiovascular stent tectorial membrane. The cutting tool comprises a bottom plate, a pressing plate is arranged above the bottom plate; the bottom plate is hinged to one side of the pressing plate and is used for pressing a film laminating sheet; a plurality of slotted holes are formed in the pressing plate, so that the upper end of the film covering sheet is communicated with the outside, and the pressed film covering sheet is cut at the slotted holes through a cutter; when the cutting tool is used for cutting cardiovascular stent membranes of different specifications, a cutter is directly used for cutting along the slotted hole of the pressing plate in the using process of the cutting tool, a ruler does not need to be used for marking scribed lines of different specifications on the whole membrane piece, the process is simplified, time is saved, the situation that the ruler needs to be used for comparison is avoided, and the production efficiency is improved. And the situation that scratches are easily caused when a cutter is used for cutting along the scribed lines is avoided, and the production safety coefficient is improved.

The invention provides a separable microcatheter and stent conveying system and method, and belongs to the technical field of neural intervention and vascular intervention. The system comprises a separable micro-catheter which is formed by detachably connecting a near-section micro-catheter (1) and a far-section micro-catheter (2) through a physical clamping structure; the stent conveying system comprises a conveying guide wire (3) and an intravascular stent (4), and the conveying guide wire (3) is provided with an anchoring stent (31) matched with the limiting cavity of the far-section micro catheter (2). The guide wire, the catheter and the stent conveying system are integrated, so that the vascular interventional operation process is obviously optimized. The system adopts a separable microcatheter design and a mechanical anchoring structure, so that a guide wire and a catheter do not need to be exchanged for many times in the operation process, and the number of times of instrument operation is fundamentally reduced. According to the invention, the operation time is shortened, the exposure time of an operator and a patient under X-rays is directly reduced, and the radiation dose is effectively controlled.

The invention discloses a degradable magnesium alloy intravascular stent based on bionic hydrogel and nitric oxide double-path release and a preparation method and application thereof. The method comprises the steps that a magnesium alloy base material is subjected to alkali heat treatment; immersing the treated magnesium alloy into a silane coupling agent for reaction; the photopolymerization reaction liquid is treated to the surface of the silanization modified magnesium alloy, and polymerization is conducted through ultraviolet irradiation; immersing the magnesium alloy with the hydrogel coating into a polyarginine solution, and grafting polyarginine onto the surface of the hydrogel; a sample is activated through EDC / NHS and then immersed in a selenocystamine solution for a reaction, and the bionic composite coating, with the exogenous / endogenous dual-path nitric oxide release function, of the degradable magnesium alloy intravascular stent is obtained. The invention successfully constructs the bionic coating integrating cell membrane-imitating anti-fouling and exogenous / endogenous dual-path NO release functions, and the coating effectively solves the key problems of corrosion control, thrombus formation resistance, functional re-endothelialization coordinated regulation and the like faced by the degradable magnesium alloy intravascular stent.