19 results about "Vascular stent" patented technology

The application discloses a peripheral biodegradable vascular stent with a partitioned reinforced structure, which is divided into at least one double-layer reinforced area and at least one single-layer flexible area along the axial direction; the double-layer reinforced area comprises an inner-layer tube stent and an outer-layer tube stent which are coaxially sleeved, and the tube walls of the inner-layer tube stent and the outer-layer tube stent are in a hollow mesh structure; the peripheral wall of the inner-layer tube stent is provided with a plurality of radially extending connecting holes, and the inner peripheral wall of the outer-layer tube stent is provided with a plurality of radially extending connecting columns which are in one-to-one correspondence with the connecting holes and are embeddedly connected; the single-layer flexible area is in a single-layer mesh structure and has the same configuration as the outer-layer tube stent; and a smooth gradient transition structure is arranged between the double-layer reinforced area and the single-layer flexible area. The application solves the problems of excessive reinforcement, sacrifice of flexibility, insufficient absolute supporting force of a single-layer structure and failure caused by different degradation steps of a multi-layer structure.

A vascular shunt stent includes a main body tube and at least one branch tube axially inserted into an inner lumen of the main body tube. The main body tube includes a tubular main membrane. At least one branch tube includes a tubular branch membrane, which is accommodated in an inner lumen of the main membrane. A first sealing film is arranged between a distal end of the main membrane and a distal end of the branch membrane to separate the inner lumen of the main membrane into a main opening and at least one first sub-opening, the first sub-opening is in sealed connection with the distal end of the branch membrane. An included angle between a plane defined by the first sub-opening is not parallel with a plane defined by the main opening.

This invention relates to the field of vascular stent fabrication technology, and discloses a method for fabricating a stent with electrodes, comprising the following steps: providing a planar stent precursor with thermally responsive deformation characteristics; forming a conductive layer on the surface of the planar precursor, and patterning the conductive layer to form at least one electrode unit and at least one conductive wire unit electrically connected to the electrode unit; forming a non-conductive material layer on at least a portion of the surface of the conductive layer; placing the planar precursor under constraint and heating it to a molding temperature below 300°C to soften the planar precursor, cause a shape memory phase transition or crystal structure transformation, and shape it into a stent structure using a mold; wherein, the non-conductive material layer maintains structural integrity and insulation properties at the molding temperature, the non-conductive material layer has windows for exposing the electrode unit, and the non-conductive material layer covers the conductive wire unit, thus avoiding thermal damage to the non-conductive material layer caused by high-temperature processes.

This invention provides a vascular stent and its preparation method, belonging to the field of medical device technology. The vascular stent includes a first stent unit and a second stent unit arranged alternately along the axial direction. The first stent unit is made of a metallic material, and the second stent unit is made of a non-metallic material. Connecting components include a connector and a receiver. The connector and receiver form a preliminary mechanical connection through an interference fit. Pressure and / or heat treatment are applied to the receiver, causing it to soften, melt, or undergo thermoplastic deformation, and after cooling and solidification, it adheres tightly to the connector. This vascular stent combines the advantages of both DES and BRS, providing reliable radial support and imaging positioning capabilities in the early stages of implantation, and restoring the vessel's own elasticity through the gradual degradation of the non-metallic material in the later stages. Simultaneously, the interference fit combined with pressure and / or heat treatment achieves a reliable fixed connection between stent units of different materials, effectively preventing loosening or detachment in the later stages.

A vascular stent, which includes: a stent body including a plurality of ring-shaped units arranged at intervals and a connecting portion connecting all the ring-shaped units into a tubular structure, wherein the tubular structure has a first covered segment and a second covered segment that are provided with membrane, and an exposed segment configured for engaging the first covered segment and the second covered segment. The vascular stent is reliable in installation, which is beneficial to reduce pre-operation and post-operation adjustment work. The stent system can realize the reliable installation of the vascular stent, which is beneficial to improve the quality of the operation and reduce the operation time.

This invention relates to the field of medical device technology, and more particularly to a method and system for controlling the deformation of cerebral vascular stents using intelligent pressure sensing. The method acquires intravascular pulsating pressure signals and the current morphology of the stent, and uses a biomechanical model to predict the deformation trend. The prediction results are matched with vascular wall stress constraints to generate a driving signal sequence for differentiated regulation of each microstructural unit. Based on contact stress feedback during the regulation process, model parameters are adaptively corrected to achieve closed-loop control. This invention achieves precise and adaptive regulation of stent deformation, improving the biomechanical compatibility between the stent and the blood vessel.

The application provides a device for measuring artificial blood vessel / stent torsional force and a use method thereof, and belongs to the technical field of blood vessel / stent torsional force testing; the technical problem to be solved is to provide an improved device structure for measuring artificial blood vessel / stent torsional force; the technical solution for solving the above technical problem is that a whole support frame is arranged, two sides of the whole support frame are respectively provided with trolleys, first fixed pulleys are fixed on the trolleys, second fixed pulleys are arranged on vertical beams of the two sides of the whole support frame, the trolleys on the two sides are connected through a moving cross beam, a sleeve is fixed on the moving cross beam, a first fixing assembly is fixed on the sleeve, a second fixing assembly is arranged below the first fixing assembly, the second fixing assembly is placed on a double-shaft experimental tensile machine, and a triangular heightener is placed on the double-shaft experimental tensile machine; the application is applied to blood vessel / stent torsional force testing.

The present disclosure provides viral microparticles comprising genetically-engineered baculoviruses (at least partially) embedded in a polymeric matrix for the local delivery of therapeutic nucleic acid molecules to the cells of a vertebrate individual (optionally in combination with a medical implant such as vascular stent platform). The viral microparticles are especially useful for promoting the healing of a wound as well as the repair of a blood vessel and prevent pathological scarring. Also provided herein are processes for making the viral microparticles, pharmaceutical compositions comprising viral microparticles as well as sup-ports comprising the viral micro particles for the locating the viral microparticles in a wound or in the vicinity of a wound.

The application belongs to the technical field of degradable vascular stents. A gradient degradation vascular stent, a composite coating structure and a preparation method thereof are disclosed. The composite coating structure of the vascular stent comprises a stent base, a dense coating coated on the surface of the base, inverted cone-shaped anchor holes arranged in an array on the base, and micro-anchor nails with barbs embedded in the anchor holes. The coating is made of non-degradable material, provides a hydrophobic barrier and insulating coverage, the anchor holes penetrate the coating and are distributed on the fatigue risk area, the micro-anchor nails are mechanically interlocked with the hole wall through the barbs to realize through riveting, the base and the micro-anchor nails are made of degradable material, and the degradation rate of the micro-anchor nails is greater than that of the base. The preparation method comprises the following steps: cutting and polishing the base, spraying to form the coating, laser processing the anchor hole array, micro-injection molding to preform the micro-anchor nails, hot pressing to embed and suction fixing. The application improves the coating anti-peeling performance, reduces the corrosion rate and promotes endothelialization through the physical anchoring + gradient degradation + insulating blocking mechanism.

The utility model discloses a cardiovascular internal medicine clinical blood vessel support relates to blood vessel support technical field, including blood vessel support ontology, the blood vessel support ontology is by a plurality of first helical frame and a plurality of second helical frame is composed, the blood vessel support ontology outside wall is close to the first arc contact frame that is provided with in the center place, and the first arc contact frame number is three, the blood vessel support ontology left and right sides are provided with the anti -displacement subassembly. The utility model discloses through the cooperation of the setting of the first arc contact frame of being connected two and the anti -displacement subassembly, makes the blood vessel support ontology support to produce both ends to expand big after opening, and the center place expands small, thereby makes the blood vessel support ontology can better be connected in the target blood vessel, thereby makes the blood vessel support ontology can better be connected in the target blood vessel, has improved the firmness of blood vessel support ontology and target blood vessel, thereby increases the stability of device, avoids the shift.

The utility model belongs to medical support technical field, concretely relates to a kind of blood vessel stent inner wall electrochemical polishing device.The blood vessel stent electrochemical polishing device includes: cathode cylinder, with power negative pole intercommunication, for placing in electrolytic cell containing electrolyte;Insulating disc is set in the bottom of cathode cylinder;The insulating disc is provided with the through-hole for accommodating support;The through-hole penetrates the upper and lower surfaces of insulating disc;Anode thimble, its one end is used to tightly fix support in through-hole, and is electrically connected with support;The other end is connected with power positive pole;And agitating device, for agitating electrolyte in cathode cylinder, make electrolyte flow through support inside.The blood vessel stent electrochemical polishing device of the utility model agitates electrolyte after agitating device, and the forced convection generated directly acts on the inner wall area of through-hole, cathode cylinder, insulating disc and through-hole force electrolyte to flow out only through through-hole, significantly improve the local flow rate of inner wall, high-speed electrolyte continuously take away the metal ion and bubble of inner wall surface, improve the polishing effect of support inner wall.

The application provides a time-sequential drug controlled-release multifunctional intracranial stent and a preparation method, relates to the technical field of vascular stents, and comprises a stent base made of a Fe-based metal material; and, from inside to outside on the surface of the stent base, a bottom coating layer composed of iron oxide nanotubes, wherein the surface of the iron oxide nanotubes is modified by polydopamine and loaded with rapamycin; a middle coating layer formed by the complex of beta-rich silk fibroin and sodium heparin; and a surface coating layer formed by the complex of silk fibroin and edaravone; wherein the setting positions of the surface coating layer, the middle coating layer and the bottom coating layer correspond to the time sequence of drug release in each coating layer, so that the corresponding drugs are released at different stages after the stent base is placed in a blood vessel, so as to adapt to the pathological evolution process in the blood vessel repair process. The application solves the problems of cerebral ischemia-reperfusion injury and vascular restenosis after the current vascular stent is placed in a cerebral blood vessel.

A cardiovascular stent comprising: an active mechanical metamaterial, comprising: first and second electrically conductive components disposed relative to each other to act as opposite electrodes to induce contact electrification; wherein the first and second electrically conductive components, along with a dielectric component serving as a skeleton of the active mechanical metamaterial, form a lattice of snapping curved semicircular-shaped segments, wherein each of the snapping curved semicircular-shaped segments has an elastic snap-through instability mechanism; and wherein the lattice comprises periodic repeatable parallel rows of the snapping curved semicircular-shaped segments.

This invention discloses a laser manufacturing method for vascular stents, belonging to the field of laser precision machining technology. It presents a design and laser manufacturing method for a vascular stent with a microfluidic drug-carrying channel. The invention provides an optimized laser cutting model and a three-dimensional projection compensation strategy for vascular stents, which are particularly suitable for the three-dimensional cutting and forming of complex and delicate vascular stent structures. Compared with traditional processing methods, this invention improves the accuracy and efficiency of two-dimensional to three-dimensional projection processing and has excellent versatility, applicable to the design and high-precision manufacturing of complex vascular stent structures.

This invention discloses a laser cutting device for vascular stents, including a mounting platform and further comprising: a jig assembly disposed on the mounting platform, including a processing seat and a clamping structure for fixing a metal sheet to be cut, the clamping structure being rotatable relative to the processing seat, and the processing seat being movable along the Y-axis of the mounting platform; a laser assembly disposed above the processing seat, including a laser generator and a 3D galvanometer, for laser cutting the metal sheet fixed by the clamping structure, and the laser assembly being movable along the X-axis of the mounting platform; a vision positioning assembly disposed around the laser assembly, including a camera, for imaging and positioning the metal sheet fixed by the clamping structure; and a cooling assembly disposed around the processing seat, including an air pipe and a nozzle, the nozzle being positioned directly opposite the metal sheet fixed by the clamping structure. Furthermore, a laser cutting method is also disclosed, which improves processing accuracy and the smoothness of the cutting edge, and reduces production costs.

This invention belongs to the field of medical device technology and discloses a porous self-expanding hydrogel vascular scaffold and its preparation method. The preparation method includes the following steps: Step 1: Coating a hydrogel solution onto the outer wall of a hollow inner tube of a mold; the hydrogel solution is obtained by dissolving hydrogel material in a solvent, and the volume concentration of the hydrogel material in the solvent is 10%~20%; Step 2: Injecting liquid nitrogen into the hollow structure of the inner tube, the liquid nitrogen creates a temperature gradient (lower inside, higher outside) on the hydrogel solution coated on the outer wall of the inner tube for directional freezing, followed by thawing and repeated freeze-thaw treatment; Step 3: Immersing the frozen inner tube in a salt solution for salting out, then immersing it in water, and finally demolding the hydrogel from the inner tube to obtain the porous self-expanding hydrogel vascular scaffold. The hydrogel vascular scaffold prepared by this method can maintain the necessary material exchange capacity while preventing cell infiltration and excessive growth of tissue inside the scaffold.

The application discloses a cardiovascular stent delivery device and belongs to the technical field of medical devices, which comprises a control handle, and a locking component is arranged on the left side of the control handle; the locking component comprises a balloon fixedly connected to the left end of an inner core pipe; a mesh metal pipe is slidably sleeved outside the balloon; a plurality of limiting grooves are formed in the outer surface of the balloon; and a limiting block is slidably connected to the inside of each limiting groove; and recesses are formed in the opposite surfaces of the upper and lower corresponding two limiting blocks. The limiting block is arranged to limit the unreleased mesh metal pipe, so that the mesh metal pipe is prevented from being dislocated or separated; the limiting block can continuously apply stable extrusion force to the mesh metal pipe, so that the mesh metal pipe is prevented from being displaced due to factors such as balloon filling during the releasing process, and in turn, the stent is prevented from being displaced or separated, the accuracy of the stent releasing is ensured, and meanwhile, the contractility of the limiting block can ensure the quick assembly of the mesh metal pipe and the stability of the mesh metal pipe after installation.

This invention discloses a femtosecond and nanosecond laser fabrication system and method for multi-size drug-loaded vascular stents, relating to the field of medical device manufacturing technology. The multi-size drug-loaded vascular stent femtosecond and nanosecond laser fabrication system includes: a processing platform; a main optical path assembly; a nanosecond laser, the laser emitted by the nanosecond laser being adapted to process drug-loaded grooves on the vascular stent; a femtosecond laser, the laser emitted by the femtosecond laser being adapted to process drug-loaded blind holes on the vascular stent; and an optical path switching device, which in a first state is adapted to guide the laser emitted by the nanosecond laser to the main optical path assembly, and in a second state is adapted to guide the laser emitted by the femtosecond laser to the main optical path assembly. The multi-size drug-loaded vascular stent femtosecond and nanosecond laser fabrication system according to embodiments of this invention can process multi-size drug-loaded structures, facilitating the meeting of rapid and sustained drug release requirements, and has advantages such as high reliability and high processing efficiency.