2783 results about "Thrombus" patented technology

The invention discloses a thrombus excision system. An embolus is extracted through a mechanical embolus extraction device, a blood vessel is dredged, and revascularization of the blood vessel is achieved. A saccule guide catheter is put at the near end of the embolus part when the embolus is extracted, blood flow is temporarily blocked, and thus a fine crushed embolus generated in the embolus extraction process is prevented from being flushed to the far end of the blood vessel; meanwhile, for a relatively large embolus, a part of thrombus can also be sucked by virtue of the saccule guide catheter, and then the residual thrombus can be extracted by virtue of a thrombus exsector. The thrombus exsector, the saccule guide catheter and a delivery microcatheter are arranged on the thrombus excision system disclosed by the invention, wherein the thrombus exsector is used as a main component, an excision spring is arranged, and the release state of the excision spring is a conical spiral state. Compared with the prior art, the thrombus excision system has the advantages that the thrombus exsector is very soft, the minimal through size is 0.014' (0.36mm), the thrombus exsector can easily enter a cerebral vessel, a near-end protection technology is adopted in the operation process, and thrombus suction is combined with mechanical embolus extraction, so that the success rate of the operation is improved, and the complications are reduced.

The invention relates to the technical field of health status assessment, in particular to a cardiovascular disease layered early warning system, which is characterized in that blood vessel compliance and pulse wave velocity are extracted, arterial dilation capacity is measured, blood vessel elasticity is calculated, blood perfusion distribution is detected, and abnormal vasoconstriction is classified on the basis of a hemodynamic state and a heart electrical activity state; in combination with the thickness of the blood vessel wall and the blood vessel stenosis rate, the plaque deposition condition is analyzed, the arteriosclerosis score is calculated, the thrombosis tendency is detected, the local blood flow blocking degree is quantified, the isolation forest algorithm is adopted, the blood flow dynamic change is calculated, the heart rhythm abnormality is analyzed, the acute vascular occlusion probability is measured, and the sudden heart rhythm abnormality risk is evaluated. And based on a gradient boosting tree algorithm, screening high-risk cases, matching medical intervention measures, setting a risk buffer mechanism, adjusting an individual health management strategy, and optimizing a cardiovascular risk hierarchical early warning system.

A method and system for determining a regional weakening (RW) value in a blood vessel using ultrasonic imaging. A set of images of a portion of a given patient's body collected over time is received. A set of measurements representing the movement of the tissue of the blood vessel is received, and the set of measurements is determined based on the set of images. The movement of the wall and lumen at least partially indicates strain. A blood flow velocity value in the blood vessel is determined based on a Doppler image, and an RW parameter indicating the state of weakening in a region of the blood vessel is determined based on at least the set of measurements, thrombus burden, and blood flow velocity value. A map showing the circumference of the blood vessel including the regional weakening value and the strain value may be displayed.

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

A thrombectomy device including a delivery catheter; a tapered dilator catheter configured to be movably disposed within the delivery catheter; and an expandable aspiration funnel configured to be movably disposed within the delivery catheter in a retracted position and at least partially outside the delivery catheter in an extended position, the funnel comprising a non-permeable covering, a diameter of a distal end of the funnel being greater in the extended position than in the retracted position, the funnel being configured to adapt its shape and length to a surrounding blood vessel such that the funnel lengthens as it narrows to retain a thrombus within the funnel. The invention also includes methods of using the device.

The invention discloses an intelligent training method for preventing lower limb thrombus and a related device, and the method comprises the steps: inputting the physiological parameters of a patient, the initial exercise ability evaluation information and the personalized rehabilitation target information into a DQN multi-mode fusion model, and generating an ankle pump exercise training scheme meeting the rehabilitation demands of the patient; monitoring ankle pump motion execution information of the patient in real time through wearable equipment; according to the ankle pump motion training scheme and the ankle pump motion execution information of the patient, a lower limb thrombus training effect evaluation result of the patient is calculated, and the lower limb thrombus training effect evaluation result comprises the blood circulation improvement degree, the joint motion range and the gait characteristics; according to a lower limb thrombus training effect evaluation result of the patient, predicting lower limb thrombus potential recovery disorder and a falling risk level of the patient, and starting a grading alarm program according to the potential recovery disorder and the falling risk level. The training effect is comprehensively evaluated through the multi-modal data fusion training method, and the lower limb thrombus rehabilitation efficiency is improved.

Systems and methods include positioning of a catheter lumen in a first position with respect to a thrombus, the catheter lumen defined by a catheter, initiating of evacuation of a tubing lumen, where the tubing lumen is not in fluid communication with the catheter lumen, determination that a pressure within the tubing lumen is equal to or less than a target aspiration pressure, and, in response to the determination that the pressure within the tubing lumen is equal to or less than a target aspiration pressure, automatic establishment of fluid communication between the tubing lumen and the catheter lumen.

Described herein are systems, devices, and methods for methods for autologous blood transfusion. For example, an apparatus may comprise a fluid conduit configured to receive a volume of fluid from a patient and a container fluidically coupled to the fluid conduit. The container may define a reservoir configured to receive the volume of fluid from the fluid conduit. The apparatus may include a vacuum conduit couplable to a vacuum source, a vent configured to vent air into the reservoir, and at least one valve configured to couple the reservoir to the vacuum conduit to generate negative pressure within the reservoir such that the volume of fluid is drawn into the reservoir, and decouple the reservoir from the vacuum conduit while coupling the reservoir to the vent such that air is vented into the reservoir at an average rate that prevents turbulent movement of the volume of fluid within the reservoir.

The invention provides an anticoagulant coating for medical instruments, which can be used in the field of regenerative medical instruments. The prepared anticoagulant coating has short-term and long-term anticoagulant performance, and in addition, the thrombin responsive nanoparticles wrapped in the hydrogel coating can selectively release a factor Xa (FXa) inhibitor apixaban according to needs, so that thrombosis is inhibited in the middle stage of implantation. In-vitro and in-vivo experimental evidences show that after the material is implanted for a long time, an organized endodermis can be seen on the surface of the material, and the material has a special antithrombotic characteristic. The dynamic adjusting system has a multi-layer protection mechanism, and a new thought can be provided for designing the surface of a contact blood material adapting to environmental conditions.

The present invention discloses a prosthetic heart valve comprising at least two valve components, a sealant covering the valve components, and an edge-sealing structure. A space is formed between the valve components covered with the sealant. The edge-sealing structure has a closed end face and connects the ends of the sealant to form a closed space within the space. The prosthetic heart valve provided by the present invention can reduce the risk of thrombosis between the valve components. Because the edge-sealing structure is flexible, it has little effect on the compression and gripping of the prosthetic valve, and the addition of the edge-sealing structure does not affect the normal function of the prosthetic valve.

The invention discloses a femoral artery paracentesis post-operation pressure-controlled hemostasis device and a monitoring intelligent control system thereof, and relates to the technical field of medical apparatuses and instruments, and the femoral artery paracentesis post-operation pressure-controlled hemostasis device comprises an assembly panel; the air bags are arranged at the bottom of the assembly panel; the air pump is arranged at the top of the assembly panel and used for controlling the air bags to contract; the control piece is arranged at the top of the assembly panel and used for controlling the air pump; the Doppler probe is arranged at the bottom of the assembly panel and used for detecting the blood flow speed of the far end of a puncture point, the hemostasis safety and efficiency are remarkably improved through multi-mode intelligent control and a real-time feedback mechanism, the vein area is accurately recognized and avoided in combination with ultrasonic and infrared spectrum analysis of the artery positioning module, the thrombus forming probability is effectively reduced, and the blood flow speed of the far end of the puncture point is detected. The pressure-time optimization model dynamically shortens the compression time (target 3 hours) based on the real-time hemostatic effect, and improves the comfort of the patient while ensuring the hemostatic effect.

The invention relates to the technical field of medical clinical auxiliary diagnosis, in particular to an orthopedic postoperative complication early detection and early warning system based on data analysis, which comprises a multi-modal sign synchronous acquisition module, a sign dynamic difference quantification module, a complication feature association module, a grading early warning decision module and a dissection calibration visualization module. Wherein the multi-modal sign synchronous acquisition module is used for acquiring postoperative data of a patient; calculating a difference quantization parameter; the complication characteristic association module is used for identifying associated risk characteristics of the osteofascia ventricular syndrome, the deep venous thrombosis and the fat embolism; and the grading early warning decision module is used for generating a three-level early warning instruction based on the associated risk characteristics. According to the system and the method, through a multi-modal sign synchronous acquisition, difference quantification and grading early warning linkage mechanism, accurate recognition, risk grade division and visual intervention guidance of postoperative complications are realized, and the continuity of postoperative monitoring and the timeliness of early warning are improved.

The invention discloses a shock wave forming device with a valve blood perfusion function, which relates to the technical field of medical instruments and comprises a catheter sheath, a shock wave forming balloon group, a shock wave generating component, a handle and a magnetic flexible net opening and closing structure. A guide wire is slidably arranged in the catheter sheath; the shock wave forming balloon set comprises a plurality of shock wave balloons, one ends of the shock wave balloons are connected with the end of the guide wire through flexible net-shaped structures, and the other ends of the shock wave balloons are connected with the end of the catheter sheath through flexible rod-shaped structures. The shock wave generating assembly comprises an axial shock wave generating electrode pair and a circumferential shock wave generating electrode pair; and the magnetic type flexible net opening and closing structure is arranged between the guide wire end part and the flexible net-shaped structure. The blood vessel can be mechanically supported or loosened; through the axial shock wave generation electrode pair and the circumferential shock wave generation electrode pair, the blocking plaque can be opened in the forward direction, and shock waves can be emitted in the circumferential direction to crack or crush calcium deposits; in addition, broken calcified plaques or aortic plaques, thrombus and the like can be captured.

The invention relates to a spontaneous cerebral hemorrhage postoperative intermuscular venous thrombosis risk prediction system based on a molecular mechanism and multi-modal data and a use method thereof, image space features are extracted through a multi-modal data level CNN to be complementary with time sequence features captured and detected by Transform, and support is provided for blood coagulation-endothelium-fibrinolysis three-channel activation degree calculation; a knowledge graph alignment module of a pathology and data level maps the cross-modal features to a unified semantic space, and corrects data conflicts with pathology time sequence constraints; and channel-space-time triple attention linkage at a space-time level is carried out, and a high-risk area is accurately marked. In a path driving layer, three-path activation degrees cooperatively adjust a dynamic time window, a single-path standard-exceeding triggering monitoring interval is shortened, and a double-path standard-exceeding amplitude is multiplied; and in a closed-loop feedback layer, system parameters are updated through confidence, pathological probability and conflict signal recursion, real-time calibration of a pathological mechanism and data is realized, and thrombus risk prevention and control efficiency is comprehensively improved.

The invention discloses an intracranial thrombus aspiration catheter and a preparation method thereof, and belongs to the technical field of medical instruments, the catheter comprises a PTFE lining, a reinforcing layer (including a coil layer and a braid layer), an outer plastic layer designed in a segmented manner, a platinum-iridium alloy developing ring and a coating. The preparation method comprises the steps of PTFE lining extrusion, coil winding, braid layer covering, segmented plastic layer forming, developing ring embedding and fixing and coating treatment and surface functionalization. Compared with the prior art, by optimizing the formula and process of the coating, the adhesive force of the coating is remarkably improved, falling is prevented, meanwhile, the surface hydrophilicity is enhanced, thrombus adhesion is reduced, and blood compatibility and operation performance are improved. In addition, the flexibility, the kink resistance and the collapse resistance of the catheter are improved through the multi-layer structural design, and the stability and the effectiveness of the catheter in a complex blood vessel environment are ensured.

A thrombus filtering device, comprising: an outer sheath tube (201), a middle sheath tube (202), a proximal filter (204), an inner sheath tube (203) and a distal filter (205). The middle sheath tube (202) comprises a pushing tube (2021) and a steerable tube, the distal end of the pushing tube (2021) being connected to the proximal end of the steerable tube, and the proximal filter (204) being connected to the pushing tube (2021). The outer sheath tube (201) is movably sleeved outside the middle sheath tube (202). The distal filter (205) is connected to the distal end of the inner sheath tube (203); and the inner sheath tube (203) movably penetrates through the middle sheath tube (202), and comprises a proximal delivery tube (2033) and a distal fixing tube (2032) which are connected to each other, the distal fixing tube (2032) being a metal tube and comprising a spring tube section (20321).

A method of extracting a thrombus from a thrombus site in a cerebral artery of a patient by advancing a first catheter into an internal carotid artery of the patient; advancing a funnel catheter within the first catheter; moving the funnel catheter and the first catheter with respect to each other to place the funnel outside of the first catheter; expanding the funnel into contact with an inner wall of the internal carotid artery at or proximal to a distal end of a carotid siphon, thereby reducing blood flow past the funnel; advancing a clot-mobilizer distally through the first catheter toward the thrombus and beyond the carotid siphon; engaging thrombus material from the thrombus with the clot-mobilizer; moving the clot-mobilizer and thrombus material proximally at least partially into the funnel; applying suction to aspirate thrombus material; and moving the funnel, the clot-mobilizer and the thrombus material proximally within the vasculature.

The invention discloses a venous thrombosis risk assessment method based on a large language model, and relates to the technical field of medical artificial intelligence, and the method comprises the steps: collecting thoracic surgery diagnosis and treatment data of a patient, carrying out the space-time alignment, generating a standard diagnosis and treatment data flow, and carrying out the homomorphic encryption of the standard diagnosis and treatment data flow, and forming an encrypted patient data package; inputting the encrypted patient data packet into a multi-task large language model, performing feature extraction and semantic coding by a feature coding layer, performing time sequence modeling and risk probability calculation by a risk quantification layer, and outputting a venous thromboembolism risk level of a patient; and performing feature decoupling and potential space mapping on the encrypted patient data packet to obtain thrombus semantic potential features. Through the multi-task large language model, the dual machine learning algorithm and the homomorphic encryption, the accuracy of venous thrombosis risk early warning is improved, and the safety of the risk assessment process is enhanced.

Disclosed herein are clot treatment systems including mechanical thrombectomy devices and clot treatment devices, and associated devices and methods. In some embodiments, a method of removing clot material from a blood vessel of patient includes inserting a catheter to proximate the clot material within the blood vessel while radially constraining a clot treatment device and an embolic protection device within the catheter. The method can further include moving the catheter proximally to deploy the clot treatment device at least partially distal to clot material within the blood vessel, and then moving the catheter further proximally to deploy the embolic protection device at least partially proximal to the clot material. The clot treatment device can include one or more relief features configured to release captured clot material if the force on the clot treatment device exceeds a threshold.

The invention relates to a deep vein thrombectomy support device which has the advantage of being convenient to clean. The inner tube assembly comprises an inner tube, a conical head assembly and a limiting key, the inner tube and the handle assembly are matched in the mode that the inner tube can slide axially but cannot rotate relative to the circumferential direction, the conical head assembly is arranged at the far end of the inner tube, the limiting key is movably installed on the handle assembly, and the limiting key selectively acts on the inner tube; the middle tube assembly comprises a middle tube and a support fixing assembly, the near end of the middle tube is connected to the handle assembly, and the far end of the middle tube is connected with the support fixing assembly; the outer pipe assembly comprises an outer pipe which can be axially and movably arranged on the middle pipe in a sleeving manner; the thrombectomy stent assembly comprises a self-expansion stent and a woven mesh, the near end of the self-expansion stent is connected with the stent fixing assembly, the near end of the woven mesh is connected to the far end of the self-expansion stent, and the far end of the woven mesh is connected to the conical head assembly.

The invention discloses a lower limb vein thrombus formation risk prediction method based on machine learning. The method comprises the following steps: step 1, constructing a triaxial thrombus evolution dynamic container space; 2, generating a pre-thrombus micro-state orbital chain; 3, determining a thrombus formation critical mutation window; 4, introducing a causal stem budget at the thrombus formation critical mutation window, and constructing a natural evolution path and a controlled path; step 5, obtaining an orbit offset difference value; 6, calculating a dynamic orbit stability index; 7, inputting the pre-thrombus micro-state orbit chain and the dynamic orbit stability index into the improved PatchTST model, and introducing a flow continuity regulation operator into a reconfiguration module to obtain a corrected orbit stability index; and 8, outputting a thrombus formation risk prediction result. According to the method, the thrombus formation risk prediction is realized by constructing a triaxial thrombus evolution dynamic container space and combining a mental structure differential equation model and an improved PatchTST model.

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

The invention relates to the technical field of nano materials and biological medicines, in particular to application of structurally reversible gel in preparation of a physical blood coagulation material, the structurally reversible gel comprises loosely assembled nanorod assemblies and a solution for dispersing the loosely assembled nanorod assemblies; the nanorod assembly comprises an inorganic one-dimensional nanorod and anions capable of participating in the assembly of the inorganic one-dimensional nanorod; the inorganic one-dimensional nanorod at least contains rare earth metal elements. The physical blood coagulation material simulates the assembly process of fibrin, shows excellent hemostasis capability independent of natural hemostasis, reduces the blood coagulation factor level, and effectively avoids the thrombus risk caused by excessive blood coagulation. In addition, the material is simple and stable in component, low in preparation cost, high in safety and capable of being stored and used for a long time.

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.

The invention relates to the field of pelvic floor muscle recovery treatment, in particular to a female pelvic floor muscle recovery treatment device and an adjusting structure thereof.The female pelvic floor muscle recovery treatment device comprises a movable base, a control box is arranged on the surface of the movable base, a hydraulic rod is installed on one side of the control box, and a recovery supporting plate is installed at the top of the hydraulic rod; a massage repairing device capable of massaging female pelvic floor muscles is installed on the upper surface of the repairing supporting plate, a movable structure is installed in the repairing supporting plate, and a lifting adjusting structure capable of freely moving is arranged above the repairing supporting plate. The top of the lifting adjusting structure is provided with an abdomen repairing structure capable of repairing female abdomen muscle tissue, and the matrix type layout of the massage vibrators can stimulate pelvic floor muscle groups in a partitioned mode, so that the biological feedback effect is enhanced. The leg repairing structure drives a sliding ball to move in an arc groove through an electric telescopic rod, switching between resistance training and passive stretching is achieved, and lower limb venous thrombosis is effectively prevented.

Disclosed herein are clot treatment systems including mechanical thrombectomy devices and clot treatment devices, and associated devices and methods. In some embodiments, a method of removing clot material from a blood vessel of patient includes inserting a catheter to proximate the clot material within the blood vessel while radially constraining a clot treatment device and an embolic protection device within the catheter. The method can further include moving the catheter proximally to deploy the clot treatment device at least partially distal to clot material within the blood vessel, and then moving the catheter further proximally to deploy the embolic protection device at least partially proximal to the clot material. The clot treatment device can include one or more relief features configured to release captured clot material if the force on the clot treatment device exceeds a threshold.

The utility model relates to the technical field of medical instruments, in particular to a blood vessel negative pressure thrombectomy device. The blood vessel negative pressure thrombectomy device comprises a negative pressure connecting pipe, a negative pressure suction device and a collecting pipeline, one end of the negative pressure connecting pipe is provided with a pipeline rotating connector, the other end of the negative pressure connecting pipe is connected with an inlet of the negative pressure suction device, one end of the collecting pipeline is connected with an outlet of the negative pressure suction device, and the other end of the collecting pipeline is connected with a pipeline rotating connector. And the negative pressure suction device is used for extracting the medium through the negative pressure connecting pipe and sending out the medium through the collecting pipeline. The thrombus aspirator has the advantages that the thrombus aspirator is simple and reasonable in structural design, thrombus can be effectively and rapidly extracted, operation is flexible, the negative pressure aspirator can freely rotate relative to a catheter entering a blood vessel for thrombus extraction due to the arrangement of the pipeline rotating connector, and a doctor can conveniently adjust the optimal operation direction in vitro.