42 results about "Total occlusion" patented technology

Microcatheter systems for crossing total occlusions are provided. Aspects of the systems include: a microcatheter with proximal and distal regions, the distal region comprising a fixed, sealed end, wherein the microcatheter comprises a lumen that receives liquid and gas, a fluid introduction module for introducing liquid and gas into the microcatheter lumen and an actuator that repeatedly pressurizes a liquid and gas mixture present within the microcatheter lumen such that the distal region of the microcatheter vibrates, moving the microcatheter across a total occlusion. Also provided are methods for modulating a total occlusion, e.g., by crossing a total occlusion or modifying a proximal cap thereof, e.g., by producing a divot or hole in the proximal cap. The systems and methods find use in a variety of different applications, including balloon angioplasty applications or other catheter-based therapies or treatments, such as conditions in which a total occlusion may be present in a vessel, including, for example, cardiovascular disease.

Method of performing one or more procedures within a patient's vasculature using a rigidizing device. The rigidizing device may be inserted through the patient's vasculature in a flexible configuration to a target region, and rigidized to form a stable base from which one or more procedures may be performed. Examples of procedures that may be performed include removing or bypassing an occlusion, placing a stent, mitral valve repair, access and / or treatment of chronic total occlusions, etc.

An apparatus for treating a total occlusion in a blood vessel may include a self-orienting device including an elongate shaft and an inflatable orienting element. The shaft includes an inflation lumen having a first noncircular shape and a working lumen having a second noncircular shape. The inflatable orienting element includes first and second inflatable members extending laterally from the shaft. An outer diameter of the shaft is 0.045 inches or less, a cross-sectional area of the first noncircular cross-sectional shape is at least 0.00013 square inches, and a cross-sectional area of the second noncircular cross-sectional shape is at least 0.00056 square inches. The shaft may include a distal tail extending distally from the inflatable orienting element, the distal tail being at least 15 millimeters long. The shaft may include a plurality of first apertures communicating with the working lumen and disposed in the distal tail.

A catheter for centrally crossing an occluded blood vessel includes a catheter body having a distal end, a proximal end, and a central passage. A rotatable drive shaft extending through the central passage and has a distal end, a proximal end, and a central lumen. A cutting tip is mounted on the distal end of the rotatable drive shaft and configured to cut through occlusive material when rotated. A plurality of spiral or other flat springs is disposed circumferentially about a distal portion of the catheter body to maintain centering of the catheter and form a passage as the catheter is advanced through a chronic total occlusion.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing an intravascular device having a distal portion with a lumen extending therein; inserting the device into the vascular lumen; positioning the distal portion in the vascular wall; and directing the distal portion within the vascular wall.

The present disclosure is a magnetically guided re-entry catheter system and method configured to direct subintimal crossing and re-entry into the artery true lumen of a guidewire during treatment of arterial chronic total occlusions. A magnet is affixed to a catheter, and the catheter is directed through the artery containing the chronic total occlusion via a guidewire. A second, ferromagnetic guidewire is directed through the artery to the opposite side of the chronic total occlusion, before crossing out of the true lumen into the subintimal. The magnetic attraction between the second guidewire and the magnet directs re-entry of the second guidewire into the true lumen once the second guidewire has passed the chronic total occlusion.

A method and systems for treating chronic total occlusions, particularly those that are difficult to treat, is disclosed. hi this approach, recanalizing the CTO is achieved using a combined antegrade and retrograde 5 approach. The proximal end of the occlusion is penetrated using an antegrade wire, using a traditional approach. Using collateral vessels, the distal end of the occlusion is crossed in a retrograde fashion. By appropriately maneuvering each member and applying radiofrequency energy between the proximal and distal ends of the occlusion, a continuous channel is created.

In one embodiment, a system includes a small-diameter tube having an elongated body, a distal tip, and an inner lumen that extends the length of the tube, the distal tip including a magnetic element that generates a strong focal magnetic field, and a crossing wire having an elongated body and a distal tip, the distal tip of the crossing wire including a ferromagnetic element that is magnetically attracted to the distal tip of the small-diameter tube when the distal tip of the crossing wire is placed in proximity to the distal tip of the small-diameter tube so as to facilitate alignment of the distal tips.

The present invention relates to a crossing device for facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein, the crossing device comprising a shaft having a distal end and a proximal end, the shaft including a coil having a plurality of filars wound in a helical shape, the coil extending from the distal end of the shaft to the proximal end of the shaft, a sleeve having a proximal end and a distal end, the sleeve extending from the distal end of the shaft and covering a portion of the coil, a tip fixed to the distal end of the shaft, and a hub fixed to the proximal end of the shaft.

An apparatus for treating a total occlusion in a blood vessel may include a self¬ orienting device including an elongate shaft and an inflatable orienting element. The shaft includes an inflation lumen having a first noncircular shape and a working lumen having a second noncircular shape. The inflatable orienting element includes first and second inflatable members extending laterally from the shaft. An outer diameter of the shaft is 0.045 inches or less, a cross-sectional area of the first noncircular cross-sectional shape is at least 0.00013 square inches, and a cross-sectional area of the second noncircular cross- sectional shape is at least 0.00056 square inches. The shaft may include a distal tail extending distally from the inflatable orienting element, the distal tail being at least 15 millimeters long. The shaft may include a plurality of first apertures communicating with the working lumen and disposed in the distal tail.

To provide a device and method for suitably centering and crossing a vascular occlusion.SOLUTION: A catheter for centrally crossing an occluded blood vessel includes a catheter body having a distal end, a proximal end, and a central passage. A rotatable drive shaft extends through the central passage and has a distal end, a proximal end, and a central lumen. A cutting tip is mounted on the distal end of the rotatable drive shaft and configured to cut through occlusive material when rotated. A plurality of spiral or other flat springs is disposed circumferentially about a distal portion of the catheter body to maintain centering of the catheter and form a passage as the catheter is advanced through a chronic total occlusion.SELECTED DRAWING: Figure 1

Exemplary embodiments of the present disclosure include systems and methods for treatment of occlusions, including coronary artery chronic total occlusions.

The present disclosure is a magnetically guided re-entry catheter system and method configured to direct subintimal crossing and re-entry into the artery true lumen of a guidewire during treatment of arterial chronic total occlusions. A magnet is affixed to a catheter, and the catheter is directed through the artery containing the chronic total occlusion via a guidewire. A second, ferromagnetic guidewire is directed through the artery to the opposite side of the chronic total occlusion, before crossing out of the true lumen into the subintimal. The magnetic attraction between the second guidewire and the magnet directs re-entry of the second guidewire into the true lumen once the second guidewire has passed the chronic total occlusion.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes inserting an intramural crossing device into the vascular lumen, positioning at least the distal tip of the crossing device in the vascular wall, advancing an orienting device over the crossing device such that an orienting element of the orienting device resides in the vascular wall, inserting a reentry device, and re-entering the true vascular lumen.

Microcatheter systems for crossing total occlusions are provided. Aspects of the systems include: a microcatheter with proximal and distal regions, the distal region comprising a fixed, sealed end, wherein the microcatheter comprises a lumen that receives liquid and gas, a fluid introduction module for introducing liquid and gas into the microcatheter lumen and an actuator that repeatedly pressurizes a liquid and gas mixture present within the microcatheter lumen such that the distal region of the microcatheter vibrates, moving the microcatheter across a total occlusion. Also provided are methods for modulating a total occlusion, e.g., by crossing a total occlusion or modifying a proximal cap thereof, e.g., by producing a divot or hole in the proximal cap. The systems and methods find use in a variety of different applications, including balloon angioplasty applications or other catheter-based therapies or treatments, such as conditions in which a total occlusion may be present in a vessel, including, for example, cardiovascular disease.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing an intravascular device having a distal portion with a side port, inserting the device into the vascular lumen, positioning the distal portion in the vascular wall, directing the distal portion within the vascular wall such that the distal portion moves at least partially laterally, and directing the side port towards the vascular lumen.

This invention provides a method and apparatus for reconstructing chronically totally occluded coronary arteries (CTOs). The method includes: obtaining multiple first markers on a forward angiographic image of the CTO during interventional treatment, each first marker corresponding to the location of multiple markers; obtaining multiple second markers on a reverse angiographic image of the CTO, each second marker corresponding to the location of multiple markers; and reconstructing the occluded segment of the coronary artery between the proximal and distal segments based on the composite image to connect the proximal and distal segments, thereby obtaining a reconstructed angiographic image containing the intact lesion. This invention effectively solves the problems of requiring an additional vascular access and bidirectional angiography in interventional treatment of CTOs in related technologies, reducing the risks and surgical costs associated with these technologies.

Provided are method and device for non-invasive detection of central arterial pressure and other intraluminal large arterial pressures. Blood flow and vascular elasticity are the main factors affecting pulse waveform acquisition. A midstream airbag strap (2) can be positioned at the same level as an intraluminal large artery in a human body, and an upstream signal channel (1) can be positioned close to the trunk of the human body and thus is very close to the intraluminal large artery so that the influence of the vascular elasticity is minimized. On the basis of the relationship between the pressure in a blood vessel and the pressure of the airbag strap outside the blood vessel under the condition that the width of the midstream airbag strap (2) is sufficient, the relationship between the blood pressure in an upstream blood vessel and the blood pressure in a midstream blood vessel under the condition that the blood flow rate at a pulse upstroke moment is equal to zero, and the relationship between the blood pressure in a blood vessel in a completely blocked state and the blood pressure in a blood vessel in a semi-active state under the condition that the blood flow acceleration is zero, a maximum value of the blood pressure in the blood vessel in the completely blocked state is obtained, which is approximately equal to the systolic pressure of the intraluminal large artery so that a measurement error caused by the blood flow is avoided to a maximum extent. The diastolic pressure of the intraluminal large artery is approximately equal to the diastolic pressure of the brachial artery or the femoral artery.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing an intravascular device having a distal portion with a lumen extending therein; inserting the device into the vascular lumen; positioning the distal portion in the vascular wall; and directing the distal portion within the vascular wall.

The application relates to the technical field of medical devices, and discloses a radiofrequency ablation guide wire system for opening a chronic total occlusion of a blood vessel. The system comprises a radiofrequency guide wire, a monitoring device, a control device, a feedback device and a radiofrequency generator. The radiofrequency guide wire has a movable electrode and a return electrode composed of a plurality of expandable and contractible return sub-electrodes. The monitoring device monitors the current, impedance and temperature of each return sub-electrode in real time. The control device judges the positional relationship of the electrodes and adjusts the radiofrequency output according to the monitoring data. The feedback device provides a position adjustment prompt in the form of sound, light or visual display. The system can further comprise functional components such as a snaring structure, a radio-opaque marker and a hollow inner core. The application improves the precision, safety and operation convenience of chronic total occlusion interventional treatment, reduces the dependence on X-ray contrast, simplifies the surgical procedure, and has a wide clinical application prospect.

An apparatus includes a processor circuit that communicates with an intravascular imaging catheter. The processor circuit controls the intravascular imaging catheter to obtain multiple intravascular images of a first blood vessel of vasculature while positioned within the vasculature. The first blood vessel includes a chronic total occlusion (CTO). The processor circuit identifies an anatomical feature associated with the CTO and / or an interventional device for treatment of the CTO in an intravascular image of the multiple intravascular images. The processor circuit outputs, to a display in communication with the processor circuit, a screen display that includes: the intravascular image; and a visual representation associated with the anatomical feature and / or the interventional device. The visual representation provides an indication, to a user, of the identification of the anatomical feature and / or the interventional device in the intravascular image.

The present invention relates, inter alia, to catheters comprising roll films and methods of using roll film catheters through stenosis or chronic total occlusion.

Devices and methods for exploiting intramural (e.g., subintimal) space of a vascular wall to facilitate the treatment of vascular disease, particularly total occlusions. For example, the devices and methods disclosed herein may be used to visually define the vessel wall boundary, protect the vessel wall boundary from perforation, bypass an occlusion, and / or remove an occlusion.

An occlusion catheter system is provided for at least partial occlusion of a vessel. The occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is fluidly connected to the proximal hub. An occlusion balloon has a proximal balloon end and a distal balloon end, the proximal balloon end being fluidly connected to the inflation catheter member. A distal catheter member is connected to the distal balloon end and includes an atraumatic tip on a distal end thereof, the atraumatic tip having a substantially circular profile in one configuration. The occlusion balloon, the inflation catheter member and the distal catheter member have a greatest outer diameter of less than 7 Fr in an uninflated condition.

A system for selecting a collateral vessel to perform a retrograde chronic total occlusion (CTO) treatment procedure is provided. The system includes one or more processors configured to: receive angiographic image data (120) representative of an occlusion in a target blood vessel; analyzing the angiography image data (120) to identify one or more candidate collateral vessels (1501... i) for approaching the occlusion in the target vessel in a retrograde direction; and assigning a suitability score to each candidate collateral vessel (1501... i), the suitability score representing a suitability of the vessel for performing the retrograde CTO treatment procedure on the occlusion.

Microcatheter systems for crossing total occlusions are provided. Aspects of the systems include: a distal crosser unit and an actuator. In embodiments, the distal crosser unit comprises: a microcatheter having a guidewire lumen; a guidewire present in the guidewire lumen and extending beyond the distal end of the microcatheter; a proximal balloon attached to both the microcatheter and the guidewire, wherein the proximal balloon is configured to longitudinally expand; and a distal anchor member present on the guidewire. In such embodiments, the actuator is configured to sequentially inflate and deflate the proximal balloon such that the distal crosser unit progressively moves across a chronic total occlusion. Also provided are methods for modulating a total occlusion, e.g., by crossing a total occlusion or modifying a proximal cap thereof, e.g., by producing a divot or hole in the proximal cap. In addition, standalone distal crosser units and kits comprising components of the systems described herein are provided. The systems, units, methods and kits find use in a variety of different applications, including balloon angioplasty applications or other catheter-based therapies or treatments.

A system and method is provided for generating ultrasound at the tip of an intravascular catheter. This may be used for the treatment of vascular occlusions, including chronic total occlusions (CTOs) and thrombotic occlusions (e.g., deep vein thrombosis, stroke, myocardial infarction). For instance, the systems and methods may be used to induce cavitation to enhance the enzymatic degradation of a vascular occlusion. In some configurations, the approach employs a hollow cylindrical transducer, electrically stimulated in the radial direction at a frequency corresponding to the length mode excitation, thereby projecting ultrasound forwards past the catheter tip. This design overcomes electrical impedance issues for the generation of low frequencies with a smaller diameter transducer capable of negotiating a coronary artery. The hole within the transducer may accommodate a guidewire to facilitate its placement adjacent to the proximal portion of the occlusion.

The invention relates to the technical field of interventional medical instruments, and particularly discloses a catheter assembly for coronary artery interventional therapy, the catheter assembly comprises a catheter body and a guide structure arranged at the far end of the catheter body, a penetrating guide cavity helpful for guiding a micro catheter is formed in the catheter body, and a guide part is of a trumpet-shaped structure and is communicated with the guide cavity; by arranging the guide section with the inner diameter matched with the outer diameter of the micro-catheter, axial guide and support can be provided in the micro-catheter propelling process, the butt joint difficulty of the micro-catheter and the guide wire is reduced, and the micro-catheter or the guide wire can be guided to enter the catheter smoothly. And the stability and smoothness of orbit establishment in the coronary artery chronic complete occlusion interventional therapy process are improved.

The present invention discloses a coronary CTA processing method and device for vascular occlusion lesions, relating to the field of medical imaging technology. A specific embodiment of the method includes: identifying the endpoints of coronary blood vessels from coronary CTA images; identifying a position to be discriminated that is suspected of having a chronic total occlusion (CTO); wherein the position to be discriminated is a blood vessel without blood flow signal between two adjacent endpoints; using a pre-determined set of CTO detection models to detect the position to be discriminated, and obtaining a CTO discrimination result for the position to be discriminated; wherein the set of CTO detection models contains a plurality of pre-trained CTO detection models corresponding to different CTO scale intervals. This embodiment can improve the CTO detection accuracy of coronary CTA images.