3450results about "Excision instruments" patented technology

A method and system are disclosed for puncturing tissue, comprising a puncture device for puncturing tissue and a supporting member for supporting the puncture device. The puncture device is capable of being insertable within the supporting member and being selectively usable in co-operation therewith during a portion of a procedure for puncturing tissue and wherein the puncture device is usable independently therefrom during another portion of the procedure.

To provide a device assembly and a method for treating heart failure by normalizing an elevated blood pressure in the left atrium of the heart of a mammal.SOLUTION: Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between right and left atria of a heart for relief of an elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the components to and from the right atrium, a tissue retention mechanism, and an optional coaxial alignment mechanism.SELECTED DRAWING: Figure 1

An intraluminal ultrasound device includes a flexible elongate member configured to be inserted into a lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion, an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member, the ultrasound imaging assembly configured to obtain imaging data while positioned within the lumen of the patient; and a radiating member disposed at the distal portion of the flexible elongate member and in communication with an ultrasound transducer positioned outside of the patient, wherein the radiating member configured to transmit ultrasound energy from the ultrasound transducer within the lumen of the patient to apply an ultrasound therapy. Associated devices, systems and methods are also provided.

An atherectomy device including a handle configured to be manipulated by a user. The device further includes a catheter comprising an outer sheath and a drive shaft carried within and rotatable relative to the outer sheath. A cutter assembly is coupled to and extends distally relative to the outer sheath. The cutter assembly includes a housing coupled to and extending distally from the outer sheath. A proximal cutting element is rotatably carried by the housing, and the proximal cutting element is coupled to and extends distally from the drive shaft. The proximal cutting element includes a cutting stem having at least one cutting feature and at least one cutting blade coupled to the cutting stem. A distal cutting element is carried by the cutting stem and is rotatable with the proximal cutting element relative to the housing. The distal cutting element includes at least one cutting blade.

Disclosed herein are clot treatment systems including catheters having multiple lumens, and associated systems and methods. In some embodiments, a clot treatment system includes a catheter having a distal tip configured to be intravascularly positioned proximate to clot material within a blood vessel. The catheter can further include / define an aspiration lumen having a distal aspiration opening and an injection lumen having a distal injection opening. The clot treatment system can further include a pressure source fluidly coupled to the aspiration lumen, and a fluid source fluidly coupled to the injection lumen. The pressure source is configured to generate negative pressure within the aspiration lumen to aspirate at least a portion of the clot material through the distal aspiration opening. The fluid source is configured to inject a fluid through the injection lumen and out of the distal injection opening into the blood vessel.

Disclosed herein are clot treatment systems including integrated / systemized mechanical thrombectomy devices and clot treatment devices, and associated devices and methods. In some embodiments, a method of removing clot material from a blood vessel of patient includes inserting a catheter to proximate the clot material within the blood vessel while radially constraining a clot treatment device and an embolic protection device within the catheter. The method can further include moving the catheter proximally to deploy the clot treatment device at least partially distal to clot material within the blood vessel, and then moving the catheter further proximally to deploy the embolic protection device at least partially proximal to the clot material.

Systems, devices, and methods for performing a cosmetic procedure on a patient are provided herein. A system includes at least one treatment device. Each treatment device having a set of multiple treatment modules. Each treatment module having at least one coring element and at least one actuation assembly. Each actuation assembly being operably attached to at least one treatment module of the set of multiple treatment modules and performing a microcoring procedure that includes the attached treatment module translating in a series of reciprocating motions. Each reciprocating motion includes each coring element of the attached treatment module being inserted into and withdrawn from target tissue of a patient.

An aspiration thrombectomy system for use with a vacuum source and an aspiration catheter includes a connection tubing configured to act as a fluid conduit between an aspiration catheter, a fluid source, and a vacuum source. The system may be provided with pressure sensors associated with the connection tubing, and controllable valves. A controller may detect pressure profiles in the connection tubing via one or more pressure sensors. The controller may determine whether connection tubing is occluded based on the detected pressure profiles, and may determine a location of occlusion. The controller may operate one or more valves to introduce a fluid medium into the connection tubing.

A system is provided which includes a cannula and a secondary device. The cannula includes an expandable member, a cannula lumen, and a cannula proximal end. The expandable member includes a proximal most end, a distal most end, at least two movable sections, with the space between the at least two moveable sections, and an impermeable membrane extending across the space between each of the at least two moveable sections. In addition, the impermeable membrane extends from the expandable member distal most end to the expandable member proximal most end. The secondary device is configured to be coaxially placed through the cannula lumen. The cannula proximal end is configured to operatively couple to a vacuum source configured to create a negative pressure to pull an undesirable material into the cannula lumen.

Described herein are methods and apparatuses for characterizing a material at a distal end of an aspiration catheter using one or more sensors. The methods and apparatuses described herein may include a plurality of sensing electrodes at a distal end region of the apparatus, and a controller configured to sense contact and / or close proximity to the sensing electrodes. These methods and apparatuses may determine or detect vessel size. These methods and apparatuses may include distal contrast ports for applying contrast material distal to the aspiration catheter. In some examples these apparatuses include one or more reference electrodes near the sensing electrodes that may enhance detection of material (e.g., clot, blood vessel wall). These methods and apparatuses may include a steerable distal end region. In some cases the apparatuses and methods may include a retriever probe to assist in capturing clot material.

Disclosed herein are clot treatment systems including catheters having multiple lumens, and associated systems and methods. In some embodiments, a clot treatment system includes a catheter having a distal tip configured to be intravascularly positioned proximate to clot material within a blood vessel. The catheter can further include / define an aspiration lumen having a distal aspiration opening and an injection lumen having a distal injection opening. The clot treatment system can further include a pressure source fluidly coupled to the aspiration lumen, and a fluid source fluidly coupled to the injection lumen. The pressure source is configured to generate negative pressure within the aspiration lumen to aspirate at least a portion of the clot material through the distal aspiration opening. The fluid source is configured to inject a fluid through the injection lumen and out of the distal injection opening into the blood vessel.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.

Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.

Described here are methods and apparatuses for tracking a clot material within a lumen of a suction catheter. For example, an apparatus as described herein may include a flexible elongate body having a suction lumen, a first pair of electrodes within the suction lumen, a second pair of electrodes proximal to the first pair of electrodes, and a controller configured to track a clot material within the suction lumen based on signals from the first pair of electrodes and the second pair of electrodes.

A device for in vivo surgery includes a cutting device rotatable by a hollow drive shaft, the cutting device being formed by a hollow anterior cutting region and a posterior region. The anterior region includes a plurality of longitudinal bore portions that are interconnected by laterally oriented cutting blade portions. The drilling portions are positioned at an angle to each other that together with the cutting blade define a conical mesh structure having a hollow interior cavity. The grid structure defines a plurality of ports between the drilling portion and the blade. A low-pressure region is formed within the hollow interior cavity, in which the cut obstructing material is drawn into the hollow interior cavity through a plurality of ports in the low-pressure region to further draw the obstructing material from the cutting device.

According to some embodiments, a skin treatment assembly comprises a handpiece comprising a distal end, the handpiece comprising a recess or cavity configured to receive a cartridge or other fluid container, a tip configured to be positioned along the distal end of the handpiece, the tip being configured to contact a skin surface of a subject during use, and at least one rollerball configured to extend to or near the tip, wherein the rollerball is configured to be in fluid communication with an interior of a cartridge or other fluid container secured to the handpiece, wherein the at least one rollerball is configured to contact the skin surface of the subject during use and to facilitate the delivery of fluids to said skin surface as the rollerball is moved relative to said skin surface.

According to some embodiments, the present technology includes device for removing obstructive material from a blood vessel lumen. For example, the device can comprise an elongated member, a cutting portion carried by a distal region of the elongated member, and a capture portion carried by the distal region of the elongated member. The cutting portion can comprise a blade configured to separate at least a portion of the obstructive material from the blood vessel wall, and the capture portion can comprise a mesh structure configured to enmesh and / or capture at least a portion of the obstructive material.

Balloon catheters, sleeves, cages, cylindrical structures and endoluminal prostheses are provided with stress-applying and spacing features coupled to expandable surfaces thereof. At least one or at least some stress-applying features are immobilized onto the surface or into pre-formed indentations formed in the expandable surface. The stress-applying and spacing features may have blunt and / or rounded contact regions which contact tissue or calcified regions in the vasculature. The contact regions dent or fracture occlusive material on the wall of a vascular lumen and / or patient valve leaflets when expanded. The spacing of features can permit blood, drug, and contrast perfusion past structures expanded in the vasculature, particularly balloon catheters.

Devices and methods are described for accessing an intracranial extravascular space of a patient. For example, this disclosure describes devices and methods for drainage of a subdural hematoma disposed within an intracranial extravascular space of a patient.

Systems and methods can involve wedge dissectors attached to strips in turn attached to medical balloons, for forming serrations within vascular wall tissue for angioplasty as well as drug delivery.

The present disclosure provides a tissue-removing catheter for removing tissue in a body lumen. The tissue-removing catheter includes an elongate drive member and a tissue-removing element. The elongate drive member has proximal and distal ends with a length and a longitudinal axis extending between the proximal and distal ends. The elongate drive member is sized and shaped to be received in the body lumen and rotates about its longitudinal axis. The elongate drive member further includes first and second longitudinal portions. The first longitudinal portion is proximal to and stiffer than the second longitudinal portion. The tissue-removing element is operatively coupled to the distal end of the elongate drive member and rotates by the elongate drive member to remove the tissue in the body lumen.

An access device for accessing an intervertebral disc having an outer shield comprising an access shield with a larger diameter (˜16-30 mm) that reaches from the skin down to the facet line, with an inner shield having a second smaller diameter (˜5-12 mm) extending past the access shield and reaches down to the disc level. This combines the benefits of the direct visual microsurgical / mini open approaches and the percutaneous, “ultra-MIS” techniques.

A method for removing a clot from a vessel involves the use of a device that can have dual layers where an inner expandable member runs within an outer expandable member. The inner expandable member can be divided into one or more sections, with a proximal section having a clot pinching structure configured to pinch the clot between the pinching structure and an outer catheter. A distal flow channel section of the inner member can be configured to create a flow channel through the clot to restore blood to the downstream vasculature. The struts of the outer expandable member can form closed cells that are not fully circumferential in a proximal portion to allow a clot to pass inside and engage the pinching structure, and fully circumferential in a distal portion to scaffold the vessel for dislodging the clot. A protective element at the distal end of the device can prevent the escape of clot fragments.

An intravascular device can comprise a carrier and an expansion apparatus. The device can be used for intravascular treatment of atherosclerotic plaque. The carrier can be reversibly expandable and collapsible within a vessel and can have ribbon strips extending between opposite ends in a longitudinal direction of the carrier. The ribbon strips can each be formed with a plurality of elongated protrusions thereon. The expansion apparatus can be used to actuate the ribbon strips each with the plurality elongated protrusions to pierce a luminal surface of the plaque with lines or patterns of microperforations which act as serrations for forming cleavage lines or planes in the plaque.

Methods and apparatuses for using intravascular ultrasound in combination with aspiration to remove intraluminal obstructive material (e.g., thrombus / clot material). These methods and apparatuses may allow the removal of intraluminal obstructive material embodiments using an integrated intravascular ultrasound transducer arrays that is arranged to enhance imaging of both target clot material and a zone of aspiration based on the position and orientation of the aspiration orifice.

The invention relates to the technical field of medical instruments, in particular to a nicking instrument based on a paper-cut structure, which comprises a destressing sleeve and a catheter seat, and further comprises a pushing section, a metal tube and a hollow head, the right end of the destressing sleeve is connected with the catheter seat, the pushing section is mounted at the left end of the destressing sleeve, and the other end of the pushing section is connected with the metal tube; the pushing section and the metal tube are coaxially connected, a PTA balloon penetrates through the catheter base, the stress relieving sleeve and the pushing section and enters the metal tube after penetrating through the pushing section, the PTA balloon is embedded in the metal tube, the tail end of the metal tube is connected with a bullet-shaped hollow head, when the PTA balloon is full, the surface of the cut metal tube begins to expand, and when the surface of the cut metal tube is expanded, the surface of the cut metal tube is expanded. When the surface of the metal tube expands to a certain degree, the expansion process of the metal tube cannot be continued due to the limitation of the included angle of the rhombus, at the moment, the continuous expansion force of the PTA balloon enables the node of the cutting section to drive the connecting rod to overturn together, and the overturned connecting rod can apply circumferential force to the narrow part of the blood vessel.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.