40 results about "Aortic arch" patented technology

A system for transvascular delivery to an aortic arch of a patient includes an embolic protection device, a connector mechanism, and a catheter or sheath for delivering the embolic protection device to a working zone. The embolic protection device includes a support frame having a distal portion and a proximal portion, and a filter member attached to the support frame and configured for preventing embolic materials from passing there through. At least one of the distal portion and the proximal portion includes a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state. The embolic protection device is pivotable axially but not radially relative to the connector mechanism.

This invention provides a covered stent and a stent assembly. The covered stent includes a first segment and two second segments respectively disposed at both axial ends of the first segment. The covered stent includes a bare stent and a covering. The bare stent includes a helical structure extending from one second segment through the first segment to the other second segment, and the helical structure has a greater ascending angle in the first segment than in the second segment. The covering covers the circumferential surface of the bare stent. The covered stent is used in a stent assembly as a branch stent for treating lesions involving the aortic arch, and it can well adapt to the anatomical structure of the aortic arch, improving treatment efficacy.

This invention discloses an automated multi-parameter assessment method, device, and medium for aortic imaging based on three-dimensional images. The method includes acquiring three-dimensional chest CT images and preprocessing them; extracting and optimizing an initial centerline based on the obtained three-dimensional vascular mask; dividing the initial centerline into ascending aorta, aortic arch, and descending aorta segments using the optimized initial centerline and the opening positions of branches on the aortic arch; extracting the average CT value of the adipose tissue surrounding the descending aorta based on the divided descending aorta segments; constructing orthogonal cross sections, performing dimensionality reduction and projection processing on each cross-sectional mask, and calculating the major and minor axes based on the farthest point pairs, outputting the major axis diameter sequence of each cross section; calculating the aortic calcification load, assessing aortic dilation and morphological variations, and evaluating the inflammatory status of the perivascular adipose tissue; and generating a comprehensive report of indicators. This invention fully utilizes existing imaging resources, improving the utilization efficiency and clinical value of medical imaging data.

The invention discloses an integrated heart valve stent with relatively short axial height, and relates to the field of heart valve stents. The invention provides an integrated heart valve stent with shorter axial height, which comprises a main body stent, and the main body stent comprises an upper stent and a lower stent which are sequentially connected from top to bottom along the axial direction of the main body stent and are integrally formed. A plurality of upper grids which are sequentially arranged in the circumferential direction of the upper support are arranged in the upper support, the upper grids are first grids or second grids, and at least one upper grid is the second grid. A plurality of lower grids are sequentially arranged in the lower support in the circumferential direction of the lower support. The top of the first grid and the top of the second grid are arrow-shaped, the arrow height of the top of the second grid is smaller than that of the top of the first grid, and the arrow included angle alpha of the top of the second grid is 60-130 degrees. The axial height of the main body stent is reduced, the bending capacity of the main body stent can be enhanced, the aortic arch passing capacity of the main body stent is improved, and meanwhile, the occurrence risk of conduction block after implantation is reduced.

This invention provides a method, electronic device, and storage medium for detecting the location of aortic dissection ruptures. Based on an image of the aorta to be detected and its true and false lumen mask images, a first search starting layer is determined according to a first search rule. Then, based on the first search starting layer and the true and false lumen mask images, the location of the aortic dissection rupture is calculated according to a second search rule. The method, electronic device, and storage medium provided by this invention can improve the detection efficiency and accuracy of aortic dissection rupture locations. Furthermore, the algorithm is simple, efficient, and has strong generalization ability, achieving fully automated detection of aortic dissection rupture locations, and is easy to implement. In addition, the method provided by this invention can determine a second search starting layer and the aortic arch location according to a third search rule, and calculate the rupture initiation location of the aortic dissection according to the second search rule, further improving accuracy.

The application belongs to the technical field of medical devices, and particularly relates to a covered stent, which comprises a stent body and a covering arranged on the stent body, wherein the stent body comprises a keel, a wave ring assembly and a sleeve joint assembly for connecting the keel and the wave ring assembly; the wave ring assembly comprises at least one curved section connected to the keel, and the curved section comprises a plurality of curved wave rings arranged on the keel in sequence; the sleeve joint assembly comprises a plurality of curved sleeves for connecting adjacent curved wave rings; and the wave ring assembly further comprises a windowing section for puncturing the covering. According to the covered stent, puncturing can be performed on the windowing section to adapt to the branch vessels on the aortic arch, and according to the shape of the vessels, the covered stent can be arranged in a preset curved shape through the curved sleeves, so as to reduce the pressure of the covered stent on the inner wall of the vessels, reduce the stimulation of the covered stent on the vessels and prevent new vessel breaks.

The utility model discloses a kind of delivery sheaths, it is related to medical instrument technical field, including sheath tube, sheath tube has sheath tube distal end first curved section, sheath tube distal end second curved section, sheath tube distal end third curved section and sheath tube main body section in turn from the distal end of sheath tube to the proximal end of sheath tube on sheath tube, the center line of sheath tube distal end first curved section and the center line of sheath tube distal end second curved section are on first plane, the center line of sheath tube distal end third curved section and the center line of sheath tube main body section are on second plane, the included angle between second plane and first plane is greater than 0 and less than 90 °;The center line of sheath tube distal end third curved section can be parallel with the center line of aortic arch, the outlet on sheath tube distal end first curved section can be directly opposite aortic valve orifice;The utility model can effectively avoid blood vessel or valve injury.

To provide a catheter with a suitable integrated embolic protection device. [Solution] The artificial heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to prevent the release of embolus into the aorta, aortic arch, or branch vessels and other vascular systems during transvascular heart valve replacement procedures. The embolic filter will typically be fixed or movably attached to the shaft of the delivery catheter proximal to the artificial heart valve.

An embolic protection device (1) for insertion into the aortic arch, comprising a filter unit (3), a frame (5) and a feeding unit (7), wherein the filter unit (3) is arranged at the frame (5) and the frame (5) provides a proximal region (9) comprising a proximal body (11) arranged in an inner region of the frame (5) and connected to the feeding unit (7), wherein the proximal body (11) comprises a first portion (13) and a second portion (15), wherein the second portion (15) is formed at one end of the first portion (13).

The invention provides an adjustable bending hemostasis delivery sheath tube for aortic arch interventional therapy, the adjustable bending hemostasis delivery sheath tube comprises a catheter sheath and a control mechanism, the control mechanism comprises a base, a driving assembly and a locking assembly, the driving assembly comprises a driving ring rotatably mounted on the base and a transmission sliding block in threaded fit with the driving ring, and the transmission sliding block is in threaded fit with the driving ring. The transmission sliding block is fixedly connected with the near end of the adjusting wire and limited to axially slide relative to the base. The locking assembly is arranged between the base and the connecting part, the locking assembly comprises a clamping block arranged outside the adjusting wire in a sleeving mode and a sliding ring arranged outside the clamping block in an axially sliding and sleeving mode, and the adjusting wire can be locked extremely reliably through surrounding type friction force generated when the sliding ring extrudes the multiple elastic clamping arms.

A stent graft for deployment in the aortic arch including at least a proximal stent ring at the proximal end of the tubular graft material, at least one fenestration provided in a side wall of the tubular graft material, an internal branch disposed within the lumen of the stent graft and extending from the fenestration. A fenestration-supporting stent ring supports the fenestration between two struts and an apex of the fenestration supporting ring. The proximal stent ring has plurality of stent units including at least one scallop unit, at least one supporting unit, and at least one body unit. The proximal apex of each scallop unit is located at a laterally extending edge of the scallop in a first circumferential region and the proximal apex of each supporting unit is located a second circumferential region. The first and second struts of each of the at least one scallop unit are shorter than the first and second struts of each of the at least one supporting unit.

Improved systems including rBGCs improved by means of stiffness; working zones and optimized transition zones can traverse the aortic arch into the common carotid and vertebral arteries from a radial approach including navigation of tortuous and individuated anatomical challenges. Mechanical Thrombectomy improved by balloon occlusion prevents thrombus showers and follows 10 years of interventional cardiology and diagnostic use of improved radial approach (TRA) with better systems, making trans-femoral (TFA)less safe and effective than this revised treatment paradigm, unexpectedly better than literature predicted in early parts of the decade. Likewise, carotid stenting may be performed during these intracranial arterial occlusion procedures without swapping out guide catheters as required by the prior art.

The utility model provides an aortic arch covered stent in-situ fenestration internal bypass catheter which comprises a catheter body, a near-end developing structure and a far-end developing structure, and a main channel and a bypass channel which are isolated from each other are arranged in the catheter body; the main channel penetrates through the pipe body in the axial direction. The flow turning channel is located on one radial side of the main channel and comprises a near-end opening and a far-end opening which are formed in the side wall of the pipe body, and a flow channel communicating the near-end opening with the far-end opening; the near-end developing structure is arranged on the side wall of the tube body and surrounds the edge of the near-end opening; the far-end developing structure is arranged on the side wall of the tube body and surrounds the edge of the far-end opening; the near-end developing structure and the far-end developing structure are different in shape, a temporary channel of the aorta true cavity and the arch branch is established, and continuous blood perfusion is provided for the brain.

Embolic protection device for insertion into an aortic arch, with a filter unit, a frame and a feed unit, wherein the filter unit is arranged at the frame and the frame provides a proximal area having a proximal shape, which is arranged in an inner area of the frame and is connected to the feed unit, wherein the proximal shape has a first part and a second part, wherein the second part is formed at one end of the first part.

A catheter device for transvascular delivery of a medical device to a cardiac valve region of a patient comprises an elongate sheath with a first lumen, a distal end for positioning at a heart valve, a second lumen that extends parallel to or in the sheath, and an expandable embolic protection filter. The filter is arranged to extend from an orifice of the second lumen and, in the expanded, covers ostia of the side branch vessels in the aortic arch.

The invention relates to the technical field of aortic arch ligation, and discloses a mouse aortic arch ligator capable of adjusting the narrowing degree, which comprises a shell, an accommodating bin is formed in the shell, an opening is formed in one side of the accommodating bin, and a limiting slide way is formed in one side, far away from the opening, of the accommodating bin; the containing bin communicates with the outer side face of the shell through the limiting sliding way, and a plurality of limiting assemblies are further symmetrically arranged in the containing bin. The driving assembly is arranged in the containing bin, and the driving assembly is in sliding connection with the containing bin through a limiting assembly; the narrowing ligation assembly is detachably assembled at the end, away from the containing bin, of the driving assembly. The mouse aortic arch constriction degree can be accurately adjusted, the structure is stable, assembling and maintaining are convenient and fast, and the accurate operation requirement of related experiments can be effectively met.

The application relates to an aortic stent and a manufacturing method thereof. The manufacturing method of the aortic stent comprises the following steps: providing a proximal stent section for being implanted into a descending aorta, a distal stent section for being implanted into an ascending aorta, and an arch stent section for being implanted into an aortic arch; providing a foldable covering film; covering the covering film on the proximal stent section and the distal stent section; providing a keel line with a pre-bent shape; and penetrating the keel line through the proximal stent section, the arch stent section and the distal stent section; wherein the proximal stent section, the arch stent section and the distal stent section jointly define a supporting cavity, the covering film is foldable, and the keel line has the pre-bent shape. The whole stent can be bent along the bending direction of the keel line, so that the elastic straightening force of the aortic stent itself can be reduced, the flexibility of the aortic stent is improved, and the complications caused by poor adhesion are reduced.

A catheter device for transvascular delivery of a medical device to a cardiac valve region of a patient comprises an elongate sheath with a first lumen, a distal end for positioning at a heart valve, a second lumen that extends parallel to or in the sheath, and an expandable embolic protection filter. The filter is arranged to extend from an orifice of the second lumen and, in the expanded, covers ostia of the side branch vessels in the aortic arch.

The utility model discloses a blood flow maintaining device and an aorta covered stent system.The blood flow maintaining device comprises a conveying sheath and a blood flow maintaining net basket, the conveying sheath comprises a sheath tube, and the blood flow maintaining net basket comprises a net basket and a pushing assembly; the net basket has an unfolded state and a folded state; the pushing assembly is connected with the net basket, and the pushing assembly is used for pushing the net basket in the sheathing canal; when the mesh basket is in an unfolded state after being released outwards from the far-end opening of the sheath tube, the mesh basket is suitable for supporting the aorta covered stent and forming a covered stent external blood flow channel on the outer side of the aorta covered stent. When the blood flow maintaining net basket is applied to an aortic arch intracavity isolation treatment operation, the net basket can ensure that the blood flow of each branch is not interrupted before branch windowing is completed, the requirements for hospital conditions and the operation level of an operator are reduced, the operation time is shortened, meanwhile, postoperative complications are reduced, and operation popularization is facilitated.

Provided herein are methods for measuring baroreflex response, and baroreflex gauge devices and systems. Such methods and devices position and expand an expandable structure at a target site within a patient's vasculature, preferably the aortic arch, and measure the baroreflex response in one or more transverse dimensions of the expandable structure. The baroreflex gauge device can optionally expand the structure to multiple expanded configurations while monitoring the patient's blood pressure to determine optimal dimensions for baroreflex response. These gauge devices and methods aid in assessing a patient's suitability for treatment and in selecting or customizing an implant to be placed within the vasculature for long-term treatment of hypertension. The baroreflex gauge device can also be integrated into an implant delivery system, allowing partial deployment to enable response measurement and full deployment to enable long-term treatment.

A cardiac pump assembly, also called a catheter assembly, is provided, having a desired anatomical shape. [Solution] This catheter assembly may include a catheter and a cannula 303 having a curved portion between its proximal and distal portions. The stationary shapes of the catheter and cannula may be selected to allow the distal portion of the cannula to be positioned at a desired angle with respect to a certain anatomical plane (e.g., the plane of the aortic arch). In some embodiments, a packaging tray 314 may be designed to position the catheter assembly in the desired stationary shape. For example, the proximal portion of the cannula 308 may be positioned at a first angle with respect to the catheter, and the proximal portion of the cannula may be positioned at one or more inserts It can be positioned at a second angle outside the plane of the packaging tray via a tether.

We provide stent graft assemblies. [Solution] A stent graft for deployment in the aortic arch, comprising a proximal stent ring at the proximal end of at least a tubular graft material, at least one fenestration provided on the side wall of the tubular graft material, and an internal branch positioned within the lumen of the stent graft and extending from the fenestration. The fenestration-supporting stent ring supports the fenestration between two struts and the apex of the fenestration-supporting ring. The proximal stent ring has a plurality of stent units, each comprising a scallop unit, a support unit, and a body unit. The proximal apex of each scallop unit is located on the laterally extending edge of the scallop within a first periphery region, and the proximal apex of each support unit is located within a second periphery region. The first and second struts of each scallop unit are shorter than the first and second struts of each support unit.

The present disclosure relates to the technical field of medical analysis, and particularly relates to a brain-heart combined imaging-based blood vessel evaluation device and method, wherein the system comprises: an image acquisition module; an image segmentation module; a model reconstruction module, configured to perform three-dimensional reconstruction and registration on the segmentation result to generate a unified watertight three-dimensional blood vessel model; a plaque classification module, configured to perform plaque classification on a blood vessel wall according to an aortic arch structure in the unified watertight three-dimensional blood vessel model to obtain a classification result; a stenosis analysis module, configured to extract corresponding blood vessel geometry data according to a coronary artery substructure and a head and neck artery substructure in the unified watertight three-dimensional blood vessel model and perform stenosis analysis to obtain a stenosis rate; and a fusion evaluation module, configured to map the classification result and the stenosis rate to the unified watertight three-dimensional blood vessel model for fusion evaluation to obtain an evaluation result. Through combined evaluation of the coronary artery, the head and neck artery and the aortic arch, the inspection efficiency is improved, and high-risk lesions are easy to find.

The invention relates to the technical field of cardiac pressure model construction, and discloses an animal cardiac pressure load model construction device, which comprises a data acquisition planning module, a data processing module, a data processing module, a data processing module, a data processing module, a data processing module and a data processing module, wherein the data acquisition planning module acquires basic physiological data such as animal heart rate and blood pressure and plans cardiac pressure load parameters such as target pressure value; the control module deploys a biocompatible air bag with an annular bag body structure on the outer side below the aortic arch of the animal through a neck incision, drives the biocompatible air bag to be periodically inflated and deflated and responds to an adjustment instruction; the monitoring and adjusting module collects data such as cardiac pressure and ejection fraction in real time, and generates an adjusting instruction after comparing the data with planning parameters; and the management module terminates inflation and deflation after the experiment reaches the standard, dissects, acquires and numbers heart tissue samples, binds associated experiment data, and stores the data to form a data set. According to the invention, the accuracy and reliability of heart-related experiments are obviously improved, and comprehensive and associated experiment support is provided for subsequent research.

The present application relates to the technical field of data processing, in particular to a pediatric transcarotid arterial and venous ECMO cannulation depth prediction method and system, comprising: selecting a data object; incision position positioning; according to the corresponding incision position, measuring the depth of the common carotid artery to the innominate artery into the aortic arch at the corresponding incision position as the ECMO arterial cannulation depth; according to the corresponding incision position, measuring the depth of the internal jugular vein to the inferior vena cava into the right atrium at the corresponding incision position as the ECMO venous cannulation depth; establishing a prediction formula; outputting the prediction result for reference; the present application summarizes the existing pediatric transcarotid arterial and venous ECMO cannulation experience, calculates and verifies the prediction formula of the transcarotid arterial and venous ECMO cannulation depth, so as to provide a reference to help doctors more accurately estimate the cannulation depth before cannulation, reduce complications caused by improper cannulation position; the prediction formula can be used as part of the standardized operation, improve the success rate and safety of ECMO cannulation.

The invention provides application of astaxanthin in preparation of drugs for preventing and treating aortic dissection, and discovers that the astaxanthin can obviously reduce the death rate of mice with aortic dissection, improve the survival rate of the mice and reduce the aortic arch dilation degree and the blood vessel inner diameter; the occurrence of the aortic dissection and the cavity and fracture of the aortic middle layer structure are inhibited, and a novel potential prevention and treatment medicine is provided for the aortic dissection.

The utility model belongs to the technical field of medical instruments, and provides an arterial cannula for VA-ECMO, which comprises a cannula body provided with a liquid guide cavity, one end of the cannula body is provided with a liquid injection port communicated with the liquid guide cavity, and the other end of the cannula body is a closed end; the tube body comprises a main body part and an arch-shaped part which are connected, the liquid injection port is formed in the end part of the main body part, and the closed end is arranged at the end part of the arch-shaped part; the arch-shaped part is in a bent arch shape matched with the aortic arch and is provided with a liquid outlet hole communicated with the liquid guide cavity. According to the artery cannula for VA-ECMO, one end of the cannula body is arranged to be the closed end, and the blood flow direction is changed through the liquid outlet hole, so that reverse blood flow of VA-ECMO through the femoral artery cannula is reduced, the left ventricular afterload is reduced more easily and more easily, complications caused by afterload increase are reduced, and the survival rate of VA-ECMO treatment patients is increased.

The invention provides a radiography device and a using method, and relates to the technical field of radiography devices.The radiography device comprises a scanning assembly, and the scanning assembly is suitable for obtaining three-dimensional information of the aortic arch and branch blood vessels on the aortic arch according to preoperative blood vessel image data of a patient; the molding assembly is suitable for customizing the pipe head according to the three-dimensional information; the radiography tube comprises a tube head and a tube body, the tube head is provided with a sealing part, the inner circumferential wall of the tube body is provided with a sealing groove suitable for containing the sealing part, and the sealing part is suitable for expanding when gas or fluid is introduced into the radiography tube. According to the radiography device, the tube head of the radiography tube is customized according to the preoperative blood vessel image data of the patient, so that the radiography tube can better adapt to individual blood vessel differences of different patients, the fitting degree and the adaptability of the tube head and the blood vessel are improved, efficient radiography and treatment are achieved, and meanwhile the radiography effect is improved. The sealing part is contained in the sealing groove and can expand when gas or fluid is introduced into the radiography tube, and the sealing performance between the tube head and the tube body is improved.

An embolic protection device (100) comprises a frame (110), a side filter screen (120) and a plurality of support rods (130) arranged at intervals, the support rods (130) comprising a first end (131), a second end (131) and at least one distal head end (132), the first end (131) and the second end (131) being connected to opposite sides of the frame (110) respectively, the first end (131), the second end (131) and the head end (132) forming a first line segment (V1), a second line segment (V2) and a third line segment (V3) respectively, the first line segment (V1) extending from the first end (131) to the head end (132) and gradually away from the frame (110), the second line segment (V2) extending from the second end (131) to the head end (132) and gradually away from the frame (110), so that the plurality of support rods (130) props up the side filter screen (120) on the plurality of support rods (130) in a direction away from the frame (110). The device can fit the side filter screen to the three branches of the aortic arch without the aid of a sheath core, and in actual application, the frame and the support rods interact and promote each other, enabling the frame to be stably fixed at the aortic arch, and also enabling each support rod to give the filter screen greater upward support, thereby enabling the side filter screen to better fit the aortic arch.

The invention discloses an application of guanylate binding protein 5 (GBP5) in preparation of a medicine for preventing, relieving or treating cardiac hypertrophy and fibrosis, in particular to a medicine for preventing, relieving or treating cardiac hypertrophy and fibrosis. GBP5 transgenic mice and non-transgenic mice are selected for testing, each mouse is divided into a false operation group and an operation group, aortic arch constriction operation is performed on the operation group, aortic arch constriction is not performed on the false operation group, and then cardiac hypertrophy, fibrosis and cardiac functions of the mice in the false operation group and the operation group are determined, so that the cardiac function of the mice in the false operation group and the operation group is determined. The influence of GBP5 gene overexpression on cardiac hypertrophy induced by aortic arch constriction is researched. Results show that the over-expressed GBP5 gene can significantly inhibit cardiac hypertrophy and fibrosis and protect cardiac functions, so that GBP5 can be used for preparing drugs for preventing, relieving or treating cardiac hypertrophy and fibrosis.