53 results about "Superior vena cava" patented technology

The invention relates to an anchor hook and methods of using the same for subannular anchoring of a transcatheter heart valve replacement, and in particular for an orthogonally delivered (side-delivered) transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the mitral or tricuspid valve from the inferior vena cava or superior vena cava, or trans-septally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring a delivery catheter to bend 90 degrees during deployment.

A method is provided that includes inserting an inflow cannula of a left ventricular assist device (LVAD) of a LVAD system into a left chamber of a heart of a patient transeptally via a right atrium and a superior vena cava (SVC). An outflow cannula of the LVAD is coupled to a left subclavian artery or a left axillary artery. Other embodiments are also described.

Systems and methods and devices are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.

The invention relates to a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

The invention discloses an intermittent occlusion balloon catheter system for treating heart failure. The system comprises a five-cavity double-balloon catheter, the five-cavity double-balloon catheter comprises a cavity tube body, a first balloon arranged in a pulmonary artery and a second balloon arranged in a superior vena cava, and the first balloon and the second balloon are both fixed to the surface of the cavity tube body; a round head is arranged at the far end of the cavity tube body, and the diameter of the round head is not larger than the outer diameter of the catheter. The near end is connected with the extension tube assembly through an injection molding head; the cavity tube body is provided with five cavity channels which are respectively communicated with the first balloon extension tube, the second balloon extension tube, the thermistor extension tube, the far-end extension tube and the near-end extension tube; the injection pump is driven by the stepping motor, and the controller adjusts the advancing and retreating motion period of the stepping motor, so that the injection pump is controlled to charge and discharge liquid to the second balloon. By intermittently blocking the superior vena cava, the heart filling pressure is reduced, and therefore heart hyperemia and volume overload are prevented.

A system and method for treating heart failure of a patient by occluding blood flow from the azygos vein to the superior vena cava while allowing blood to flow through a shunt from the right pulmonary artery to the azygos vein. The system can include an occluder with an expandable cage positioned in the azygos vein to selectively control the flow of blood to the superior vena cava. The occluder can expand and collapse based on pressure measurements received from implanted pressure sensors.

The invention relates to an anchor hook and methods of using the same for subannular anchoring of a transcatheter heart valve replacement, and in particular for an orthogonally delivered (side-delivered) transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the mitral or tricuspid valve from the inferior vena cava or superior vena cava, or trans-septally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring a delivery catheter to bend 90 degrees during deployment.

A system and method for treating heart failure of a patient by occluding blood flow from the azygos vein to the superior vena cava while allowing blood to flow through a shunt from the right pulmonary artery to the azygos vein. The system can include an occluder with an expandable cage positioned in the azygos vein to selectively control the flow of blood to the superior vena cava. The occluder can expand and collapse based on pressure measurements received from implanted pressure sensors.

A method may involve creating a first opening in a right pulmonary artery and a second opening in a superior vena cava. A shunt may be percutaneously delivered into the first opening and the second opening. A stent may be percutaneously delivered into the superior vena cava adjacent to the shunt. The stent can comprise a covering to at least partially prevent flow of blood from the shunt through the stent and / or may be at least partially flexible to allow the stent to bend away from walls of the superior vena cava in response to inflow of blood through the shunt. The stent may be sized to seal against the superior vena cava at a first end and a second end of the stent to trap blood between the stent and the walls of the superior vena cava.

Systems and methods and devices are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.

Apparatus and methods for repairing a cardiac valve, e.g., a tricuspid valve, are provided. The apparatus may include a prosthetic device coupled to an elongated support coupled to a stent configured to be implanted within a vessel, e.g., the superior vena cava, to suspend and maintain the prosthetic device within the cardiac valve. The support may include a proximal, delivery portion detachably coupled, in a delivery state, to a distal, implantable portion coupled to the prosthetic device. The prosthetic device may be formed of biocompatible material coupled to a frame, and may have prosthetic leaflets that allows blood to flow therethrough in one direction during diastole, but prevents blood regurgitation during systole. The stent further may include features configured to resist migration of the stent within the vessel, as well as to prevent in-folding of the stent during deployment.

Systems and methods and devices are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.

Prosthetic heart valves may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valves are implanted using catheter-based deployment systems that include multiple control wires. In particular implementations, the deployment systems can include a retrieval catheter that can be used to recapture the prosthetic heart valve back into a delivery sheath after being expressed from the delivery sheath. The prosthetic heart valves can include a plurality of optional suture knots to enhance migration resistance. Some delivery catheter systems can include a controllably bendable control catheter and / or a deflectable catheter to facilitate deployment of the prosthetic heart valve to a native tricuspid valve site via a superior vena cava or inferior vena cava.

The invention relates to constriction devices and methods for deploying a laterally delivered prosthetic heart valve in a native annulus. The present invention relates to anchoring channels and subannulus anchors for transcatheter heart valve replacement (A61F2 / 2412), and in particular for transcatheter prosthetic heart valves with orthogonal delivery of an annulus support frame having a compressible wire unit, the compressible wire unit facilitates rolling and folding of the valve in a longitudinal direction or orthogonal to a central axis of the flow control member, allowing delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve, or trans-atrial delivery and deployment to the mitral valve, or delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve. The valve has a height of about 5 mm to 60 mm and a diameter of about 25 mm to 80 mm without the need for an over-diameter catheter and without the need for delivery and deployment from the catheter at an acute access angle.

The present invention relates to an anchoring channel and a subannular anchor for transcatheter heart valve replacement (A61F2 / 2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having an annular support frame having a compressible wire unit that facilitates rolling and folding of the valve longitudinally or orthogonally to the central axis of the flow control component, thereby allowing very large diameter valves to be delivered and deployed from the inferior vena cava or superior vena cava to the tricuspid valve, or delivered and deployed transatrially to the mitral valve, the valve having a height of approximately 5 mm-60 mm and a diameter of approximately 25 mm-80 mm, without the need for an overly large diameter catheter and without the need for delivery and deployment from the catheter at an acute approach angle.

The prosthetic heart valve may be delivered to a target native heart valve site via one or more delivery catheters. In some embodiments, the prosthetic heart valve includes structural features that securely anchor the prosthetic heart valve to an anatomical structure at a native heart valve site. Such structural features may provide robust resistance to migration. In addition, the prosthetic heart valve may include structural features that improve sealing between the prosthetic valve and native valve anatomy to mitigate perivalvular leakage. In particular embodiments, the prosthetic heart valve occupies a small delivery profile, facilitating a smaller delivery catheter system for advancement to the heart. Some delivery catheter systems may include a curved inner catheter to facilitate deployment of the prosthetic heart valve to the native tricuspid valve site via either the superior vena cava or the inferior vena cava.

The utility model relates to a multifunctional catheter for superior vena cava triggering focus mapping and phrenic nerve pace-making, which comprises a catheter body and a spiral electrode tip arranged at the far end of the catheter body, and a plurality of pace-making electrode groups are arranged on the spiral electrode tip. The catheter body and the spiral electrode tip are telescopically arranged in the sheath and can extend out of the open end of the sheath; the spiral electrode tip is in a contraction configuration in the sheath, and can be converted to an expansion configuration when extending out of the sheath and extending into a phrenic nerve pace-making area in the superior vena cava; the starting end of the spiral electrode tip is connected with a center mapping catheter coaxial with the catheter body, and a plurality of mapping electrode sets are arranged on the center mapping catheter. Compared with the prior art, the multifunctional catheter has the advantages that the spiral electrode tip can be stably attached to the inner wall of the superior vena cava, and the multifunctional catheter can be matched with a central mapping catheter to map a superior vena cava trigger range while playing a pace-making role.

Systems and methods are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The system may include sensors to determine the degree of occlusion of the superior vena cava. The occlusion system may be used to reduce volume in a heart and facilitate a cardiac procedure. The occlusion system may be used to relieve an overloaded chamber during and / or after deploying a VAD.

Systems and methods are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The system may include sensors to determine the degree of occlusion of the superior vena cava. The occlusion system may be used to reduce volume in a heart and facilitate a cardiac procedure. The occlusion system may be used to relieve an overloaded chamber during and / or after deploying a VAD.

The utility model belongs to the field of medical catheter instruments, and particularly relates to a dialysis catheter. Comprising a catheter extending in the longitudinal direction, the catheter comprises a catheter body at the far end and at least two auxiliary catheters communicated with the near end of the catheter body, inner cavities correspondingly communicated with the auxiliary catheters are formed in the catheter body, and side holes corresponding to the far ends of the inner cavities are formed in the catheter body; the base is connected to the near end of the auxiliary catheter and is communicated with the connected auxiliary catheter. The whole dialysis catheter is buried subcutaneously, the wound of the puncture medical instrument to the skin is small and easy to recover, the infection risk is greatly reduced, the base is not exposed out of the body and is relatively stably connected with the skin, the risk that the base is accidentally dragged out does not exist, and the influence on the life of a patient is also remarkably reduced. In addition, sterile liquid can be injected into the dialysis catheter through the side hole, so that the catheter cannot be tightly attached to the superior vena cava, the probability of thrombus formation is reduced, and the dialysis catheter has the advantages of being not prone to infection, small in influence on life and friendly to patients.

Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava. The TDPS can be designed to seamlessly interface with any commercially available positive-pressure ventilatory assistance / support equipment such as is commonly in use in hospital intensive care units (ICU) for treating critically ill patients with breathing insufficiencies, pain, trauma, sepsis or neurological diseases or deficits.

The utility model relates to the technical field of medical apparatus and instruments, and provides a double-cavity femoral vein cannula which comprises a body, a first channel, a second channel, a first cavity and a second cavity. The outer pipe is arranged at one end of the body, an outlet of the outer pipe is communicated with an inlet of the first channel, and a plurality of first drainage holes are formed in the pipe wall of the outer pipe in the axial direction of the outer pipe at intervals; one end of the inner tube is inserted into the outer tube and communicated with the inlet of the second channel, the other end of the inner tube extends out of the outer tube to form an exposed section, and a port of the exposed section forms a second drainage hole; and a gap for lower cavity venous blood to pass through is reserved between the outer wall of the inner tube and the inner wall of the outer tube. According to the double-cavity femoral vein cannula, due to the fact that the first drainage holes are formed in the whole outer tube in the length direction, the inner tube can be allowed to be adjusted within a certain range, and the inferior vena cava drainage effect can be taken into consideration while the superior vena cava drainage effect is guaranteed.

Systems and methods and devices are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.

The present invention relates to an access and occluder device, in particular a heart valve regurgitation drum and optional occlusion disc and / or annular stent for managing and providing a level of intentional regurgitation in a transcatheter heart valve replacement, in particular an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a first inner regurgitation control component and an outer annular support frame having compressible wire cells.SOLUTION: The compressible wire cells facilitate folding flat along the z-axis and compressing the valves vertically along the y-axis or orthogonal to the central axes of the flow control components, enabling the delivery and placement of very large diameter valves from the inferior or superior vena cavae to the tricuspid valves or transatrially to the mitral valves, having heights of about 5 to 60mm and diameters of about 25 to 80mm, without the need for an oversized catheter and without the need for delivery and placement from a catheter with a sharp approach angle.SELECTED DRAWING: Figure 3

The present invention relates to a catheter that minimizes or eliminates the recirculation of oxygenated blood. The catheter of the present invention can be used to drain blood from multiple points in the patient, namely the superior vena cava, right atrium, and the right ventricle, while returning blood to the patient's pulmonary artery. Further, the catheter of the present invention is less likely to be moved or dislodged than catheters currently available in the art, thus making the catheter particularly useful for portable lung assist devices. The present invention also relates to methods for inserting the catheter into the patient and using the catheter with a lung assist device.

In some embodiments, a method includes a shaft having a side catheter guide attached thereto via a guide coupler into an inferior vena cava and a superior vena cava such that the guide coupler is disposed in a right atrium, and applying a distal force to a proximal portion of the side catheter guide such that a distal end of the side catheter guide deflects laterally about the guide coupler towards a septum. The method further includes extending a side catheter that is disposed within the side catheter guide distally from the side catheter guide towards and into contact with the septum. The method further includes, with the side catheter in contact with the septum, extending a septum penetrator that is slidably disposed within the side catheter distally from the side catheter such that the septum penetrator pierces the septum.

To provide a method and a system for improving cardiac function in patients suffering from heart failure, including patients with reduced ejection fraction, and for treating pulmonary hypertension and / or cardiorenal syndrome.SOLUTION: Systems and methods and devices are provided for treating conditions such as heart failure and / or pulmonary hypertension by at least partially occluding blood flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter 31 with an occlusion device 32 is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patient's superior vena cava (SVC), which reduces cardiac filling pressures, and induces a favorable shift in the patient's Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure.SELECTED DRAWING: Figure 43

The present application provides a tricuspid valve device, which may include a frame and an associated new prosthetic valve. The frame serves as a stabilizing structure, with its head extending into the morphological or functional right atrium (upstream) and its tail extending into the morphological or functional right ventricle (downstream). The frame includes an atrial dome with struts that conform to the atrium without blocking blood flow from the incoming great veins (i.e., the superior vena cava and the inferior vena cava) or other abnormal veins and / or tributaries. The frame also includes ventricular struts placed in the right ventricle to secure the new prosthetic valve in a desired position. The assembly of the frame and valve is retractable so that the assembly can be placed in a vascular catheter prior to deployment and then self-expanded when released in the heart (heart chamber).

A method of implanting a prosthetic heart valve at a native tricuspid valve region includes delivering a prosthetic heart valve to the native tricuspid valve region via the inferior vena cava or the superior vena cava and deploying the prosthetic heart valve from a sheath of a delivery apparatus. The prosthetic heart valve includes a radially compressible and expandable frame assembly having an inflow end, an outflow end, and a double-body structure having an annular inner frame and an annular outer frame. The outer frame preferably includes an atrial flange portion configured to contact an atrial face of the native tricuspid valve region. The prosthetic heart valve can further include a plurality of ventricular anchors, each comprising a free end portion and a fixed end portion connected to and extending from the frame assembly at a location spaced from the outflow end of the frame assembly.