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116 results about "Left atrium" patented technology

The left atrium is one of four chambers in the human heart. It receives oxygenated blood from the pulmonary veins, and pumps it into the left ventricle, via the mitral valve. Atria facilitate circulation primarily by allowing uninterrupted venous flow to the heart, preventing the inertia of interrupted venous flow that would otherwise occur at each ventricular systole.

System for perfusion of biological samples

PCT designated stageWO2025255395A2Dead animal preservationNormothermic perfusionLeft atrium
A normothermic perfusion circuit can be used to perfuse a donor heart after transportation and before transplantation. The circuit can drain the organ storage container of cold preservation solution, perfuse the aorta of the heart with warm fluid to initiate heart activity, and then perfuse the left atrium of the heart with warm fluid to bolster heart activity and evaluate heart viability. Heart viability can be determined using parameters measured by sensors in the circuit.
Owner:PARAGONIX TECHNOLOGIES INC

System for perfusion of biological samples

PendingUS20250374918A1Dead animal preservationNormothermic perfusionLeft atrium
A normothermic perfusion circuit can be used to perfuse a donor heart after transportation and before transplantation. The circuit can drain the organ storage container of cold preservation solution, perfuse the aorta of the heart with warm fluid to initiate heart activity, and then perfuse the left atrium of the heart with warm fluid to bolster heart activity and evaluate heart viability. Heart viability can be determined using parameters measured by sensors in the circuit.
Owner:PARAGONIX TECHNOLOGIES INC

Left heart data analysis method and system based on image segmentation

The invention provides a left heart data analysis method and system based on image segmentation, and relates to the technical field of medical image processing. Comprising the following steps: acquiring cardiac ultrasound image data and preprocessing; performing image segmentation on the preprocessed image data to obtain a segmentation result including a left ventricle, a left ventricular wall and a left atrium; searching a boundary line of the left ventricle and the left atrium, selecting two boundary points corresponding to the minimum and maximum abscissas in the boundary line as left and right mitral valve ring points respectively, and establishing a long axis based on the mitral valve ring midpoint and the cardiac apex point; modeling the ventricle into a structure formed by superposing a plurality of discs along the long axis direction, and obtaining the diameter of the corresponding disc; based on the obtained diameters of the corresponding discs, the left ventricular volumes in the diastolic period and the systolic period are calculated respectively, and the left ventricular ejection fraction is calculated. According to the method, image segmentation and geometric modeling are fused to achieve accurate calculation of the cardiac ejection fraction, meanwhile, the accuracy of cardiac structure image segmentation is improved, and an interpretable ejection fraction estimation process is achieved.
Owner:SHANDONG UNIV

Devices, systems, and methods for managing blood flow

ActiveUS12490989B2StentsSurgical needlesVascularizesRetrograde Flow
Devices, systems, and methods for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium are disclosed. Devices and methods include a method for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium, the method comprising: implanting a variable occluder in a coronary sinus region proximate a left atrium, wherein the variable occluder is configured to gradually increase a level of blood flow restriction over a period of days to enable a venous system of the myocardium to compensate for increased pressure caused by the gradual increase in the level of blood flow restriction; and following venous system compensation, shunting oxygenated blood flow into the coronary sinus to cause retrograde flow of oxygenated blood in at least a portion of the venous system of the myocardium to thereby enable revascularization of the myocardium.
Owner:REVASCARDIO LTD

Valve stent for mitral valve replacement

ActiveCN120788785AHeart valvesBioprosthetic mitral valve replacementAnatomy
The invention relates to the technical field of medical instruments, in particular to a valve stent for mitral valve replacement, which comprises an integrally formed stent, the stent is formed by a plurality of folding parts along the circumferential direction and the axial direction, each folding part comprises two folding arms which are connected in a V shape, and two ends of each folding arm are respectively a first connecting end and a second connecting end; the first connecting end of each folding arm is connected with the first connecting end of the adjacent folding arm in the circumferential direction, and the second connecting end of the same folding arm is connected with the second connecting end of the other adjacent folding arm in the circumferential direction; and a wave-shaped connecting rod is arranged between each folding arm and the adjacent folding arm in the axial direction. The stent has the beneficial effects that the shortening rate of the stent is effectively reduced, and implantation is more convenient through the left atrium.
Owner:CHENGDU SILARA MEDTECH INC

Shunt for redistributing atrial blood volume

Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.
Owner:WAVE LTD V

Automatic counting method and system for ultrasonic microbubbles in right heart acoustic radiography

The invention provides an automatic counting method and system for ultrasonic microbubbles in right heart acoustic radiography. The method comprises the following steps: acquiring a cardiac radiography image of a patient through high-resolution ultrasonic equipment; extracting a region of interest of the cardiac angiography image based on the cardiac vascular structure, and performing image registration operation on the cardiac angiography image by taking the region of interest as a reference point to obtain a registered image; carrying out pixel-by-pixel addition on two frames of pulse images with opposite phases in the registered image to obtain an enhanced image; determining the high-echo bright spots in the enhanced image as suspected microbubbles, and performing denoising processing according to the feature similarity to obtain real microbubbles; judging pathological conditions according to whether real microbubbles exist in the left atrium or not; if the real microbubbles exist in the left atrium, grading the abnormal blood flow according to the change data of the microbubbles in the left atrium and the right atrium. According to the method, through high-precision image registration, multi-modal feature analysis and dynamic parameter fusion technologies, the microbubble detection accuracy is improved, and quantitative grading of pathological conditions is achieved.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Docking devices for prosthetic implants

PCT designated stageWO2026080290A1Heart valvesAnatomyLeft atrium
Docking devices for securing a prosthetic valve at a native valve are provided. The docking device can include a coil and a guard member. The coil includes a plurality of helical turns when in a deployed orientation. The guard member may be attached to the coil by being coupled to at least a portion of a helical turn thereof. The docking devices include a atrial functional turn configured to enhance the transient stage stability of the docking device in the left atrium of the heart.
Owner:EDWARDS LIFESCIENCES CORP

Transcatheter device for interatrial anastomosis

ActiveUS12648787B2Guide needlesIncision instrumentsLeft atrial pressureRight atrium
The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.
Owner:TEXAS MEDICAL CENT

Arrhythmia type inference device, arrhythmia type inference method, and recording medium

PendingUS20260248488A1Pattern recognitionTarget signal
An arrhythmia type inference device includes: an obtaining section that obtains a target signal waveform indicating a time-series change in the area of a region, which is at least one of a left atrium, a left ventricle, a right atrium, and a right ventricle, the target signal waveform being generated by analyzing an image of a heart of a target subject; and an inference section that infers the type of tachyarrhythmia suffered by the target subject based on the shape of the target signal waveform having a frequency in a frequency band higher than a reference frequency band predetermined as a normal range. This allows the arrhythmia type inference device to accurately infer the type of tachyarrhythmia from the image obtained by image-capturing of the heart.
Owner:KANADEVIA CORP +1

Leaflet capture and anchor deployment system

ActiveUS12636153B2Suture equipmentsSurgical needlesChordae tendineaeAnatomy
Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.
Owner:PIPELINE MEDICAL TECHNOLOGIES INC

Device allowing large bore transseptal access with subsequent atrial re-access and method thereof

The present disclosure relates to medical devices. More particularly, this disclosure describes a vascular device allowing large bore transseptal access with subsequent atrial re-access by preplacing closures / tissue approximating sutures prior to creating a septostomy. Generally, the device may include a delivery catheter for puncturing and cutting the interatrial septum. An anchor of the delivery catheter may secure the suture in an atrium to a septum wall, for example, the left atrium. Incisions may be made by an expandable cutting implement which may use mechanical or radio frequency (RF) energy without interfering with the suture. A therapeutic instrument may be advanced through the tissue plane after the incisions are made by the cutting implement. Closure of the incision may be performed with the previously placed sutures.
Owner:AMX TECHNOLOGIES LLC

Standardized coordinate systems for mapping three-dimensional structures

The present technology relates to standardized coordinate systems for mapping three-dimensional structures. An exemplary method includes: obtaining imaging data including a representation of a left atrium of a subject; identifying anatomical features represented in the imaging data, the anatomical features including pulmonary veins that connect to the left atrium; generating a 3D surface mesh corresponding to the left atrium; determining a reference point on the 3D surface mesh based on locations of junctions of the pulmonary veins with the left atrium; establishing a reference axis based on the reference point; determining, on the 3D surface mesh and based on the reference axis, lines of longitude; determining, on the 3D surface mesh, lines of latitude along the lines of longitude; assigning coordinate values to points on the 3D surface mesh based on the lines of longitude and latitude; and generating a 2D map of the left atrium using the coordinate values.
Owner:RGT UNIV OF CALIFORNIA

Adjustable interatrial shunts and associated systems and methods

ActiveUS12533500B2Heart valvesWound drainsSeptal wallFlow diverter
The present technology is generally directed to interatrial shunting systems and associated devices and methods. For example, a system configured in accordance with embodiments of the present technology can include a shunting element implantable into a patient at or adjacent a septal wall. The shunting element can have a lumen that fluidly connects a left atrium and a right atrium of the patient to facilitate blood flow therebetween when the shunting element is implanted. In some embodiments, the system further includes a flow control element to selectively control blood flow between the left atrium and the right atrium.
Owner:SHIFAMED HLDG LLC

Heart microperfusion device, method and system

PendingCN121311201AStentsOcculdersCoronary sinusFlow diverter
A cardiac microperfusion device is disclosed that includes an integrated flow restrictor and a diverter from the left atrium to modulate flow within the blood vessel, particularly flow within the coronary sinus. Related methods and systems are also disclosed.
Owner:VAHATICOR INC

Ultrasonic imaging and backscattering system and method

An ultrasound imaging and backscatter system includes an ICE ultrasound catheter having an ultrasound pMUT transducer array disposed within a distal end of the ultrasound catheter and including a plurality of transducer array elements disposed on a substrate. One end of the catheter shaft is connected to the handle assembly and the other end is connected to the ultrasonic transducer array. The catheter shaft accommodates an electronic flexible cable in communication with the signal trace and directs each of the plurality of transducer array elements to transmit and receive an ultrasound beam, receives at least one signal from the plurality of transducer array elements, and constructs at least one image characterizing one or more tissue components of the scanned object. An ultrasound imaging system is used to measure tissue thickness, tissue scar, and lesion assessment for left atrium, right atrium, left ventricle, and right ventricle tissue wall characteristics and other intracardiac tissue anomalies.
Owner:BOSTON SCIENTIFIC SCIMED INC

Method for robotic assisted heart transplant

PendingUS20260076762A1Suture equipmentsPeptide/protein ingredientsSequential anastomosisSuperior vena caval
A method for performing a robotic-assisted orthotopic heart transplant includes forming a working port subareolarly by a mini-thoracotomy at a working intercostal space, forming additional ports for robotic arms, and arranging robotic arms through the ports. A first robotic arm with first forceps extends through a second port lateral to a mid-clavicular line, while second and third robotic arms containing an imaging device and second forceps operate through the working port. A fourth robotic arm with scissors or needle holder extends through a third port proximal to an anterior axillary line. The method includes cannulating for cardiopulmonary bypass, opening the pericardium, cross-clamping the aorta, removing the native heart, and performing sequential anastomoses of the donor heart including the left atrium, pulmonary artery, aorta, inferior vena cava, and superior vena cava.
Owner:KING FAISAL SPECIALIST HOSPITAL & RES CENT

Vascularly anchored cardiac sensor

ActiveCN114554946BStentsEndoradiosondesSeptal wallImplanted device
A method of sensing a physiological parameter involves advancing a delivery catheter to a right atrium of a heart of a patient via a transcatheter access path, advancing the delivery catheter through an atrial septal wall into a left atrium of the heart, deploying a distal anchor of a sensor implant device from the delivery catheter, anchoring the distal anchor of the sensor implant device to a first pulmonary vein, withdrawing the delivery catheter from the first pulmonary vein, thereby exposing at least a portion of a sensor module of the sensor implant device in the left atrium, deploying a proximal anchor of the sensor implant device from the delivery system, anchoring the proximal anchor of the sensor implant device to a second pulmonary vein, and withdrawing the delivery catheter from the heart.
Owner:EDWARDS LIFESCIENCES CORP

Devices and methods for coronary sinus pressure relief

A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.
Owner:CORVIA MEDICAL INC

Valve holder for use in mitral valve replacement

ActiveCN120788785BHeart valvesBioprosthetic mitral valve replacementLeft atrium
The application relates to the technical field of medical devices, in particular to a valve stent for mitral valve replacement, which comprises an integrally-formed stent, the stent is composed of a plurality of folding parts in the circumferential and axial directions, the folding part comprises two V-shaped connecting folding arms, the two ends of the folding arm are respectively a first connecting end and a second connecting end; the first connecting end of the folding arm is connected with the first connecting end of the circumferentially-adjacent folding arm, and the second connecting end of the same folding arm is connected with the second connecting end of the circumferentially-adjacent other folding arm; a wave-shaped connecting rod is arranged between the folding arm and the axially-adjacent folding arm. The beneficial effect is that the shortening rate of the stent is effectively reduced, and the implantation is more convenient through the left atrium.
Owner:CHENGDU SILARA MEDTECH INC

Heart chamber prosthetic valve implant with elevated valve section and single chamber anchoring for preservation, supplementation and / or replacement of native valve function

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device with an elevated valve section and comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and / or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed.
Owner:4C MEDICAL TECHNOLOGIES INC

A coronary sinus and left atrium shunt system

This application relates to a coronary sinus and left atrium shunt system, belonging to the field of medical device technology. The system described in this application, by setting up a puncture component and a shunt component including a cutter, allows for the cutting of a portion of myocardial tissue between the coronary sinus and the left atrium, forming a shunt orifice. This establishes a shunt channel between the coronary sinus and the left atrium, effectively avoiding the embolism risk associated with atrial septal shunts and improving coronary artery blood perfusion, potentially benefiting myocardial recovery.
Owner:SHENZHEN SHUOXIN INTELLIGENT MEDICAL TECHNOLOGY CO LTD

Implantable intracardiac blood pressure monitoring sensor

The invention provides an implantable intracardiac blood pressure monitoring sensor, which relates to the field of in-vivo implantable devices, and comprises a support shaft, a pressure-sensitive chip fixed at one end of the support shaft, a fixing hook positioned at the other end of the support shaft and used for hooking a conveying device, and an inductance coil positioned at the other end of the support shaft and used for hooking the conveying device, the inductance coil is connected to the supporting shaft in a sleeving mode and coupled with the pressure-sensitive chip, the support is composed of a plurality of high-elasticity memory alloys and arranged around the supporting shaft, the two ends of the support are connected to the two ends of the supporting shaft respectively, and the middle of the support is supported on the inner wall of the left atrium of the heart. The sensor has the technical effects of accurate positioning, firm anchoring, long-term stable monitoring, good biocompatibility and the like, and the safety and the reliability of real-time monitoring of the intracardiac blood pressure are remarkably improved.
Owner:NINGBO XINLIANXIN MEDICAL TECH CO LTD

Devices, systems, and methods for managing blood flow

ActiveUS12667361B2VeinCoronary sinus
Devices, systems, and methods for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium are disclosed. Devices and methods include a method for causing retrograde oxygenated blood flow in at least a portion of the venous system of the myocardium, the method comprising: implanting a variable occluder in a coronary sinus region proximate a left atrium, wherein the variable occluder is configured to gradually increase a level of blood flow restriction over a period of days to enable a venous system of the myocardium to compensate for increased pressure caused by the gradual increase in the level of blood flow restriction; and following venous system compensation, shunting oxygenated blood flow into the coronary sinus to cause retrograde flow of oxygenated blood in at least a portion of the venous system of the myocardium to thereby enable revascularization of the myocardium.
Owner:REVASCARDIO LTD

Catheter-based extracorporeal membrane oxygenation (ECMO)

PCT designated stageWO2025226752A1Balloon catheterMulti-lumen catheterVeinMedicine
Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.
Owner:VANTIS VASCULAR INC

Adjustable left room drag hook

The utility model relates to the technical field of surgical auxiliary instruments, and discloses an adjustable left atrium retractor which comprises a handle and a quick fixing structure, and the quick fixing structure is arranged on the lower side of the handle and used for being fixedly connected with a sternum retractor; the universal supporting rod comprises a movable joint and a moldable iron wire; the universal supporting rod is arranged at the front end of the handle and is fixed through the moldable iron wire and the movable joint after being bent and deformed; the blade is connected with the front end of the universal supporting rod through the multidirectional rotating joint; and the antifouling soft sleeve wraps and is arranged on the rod body of the universal supporting rod. Compared with the prior art, the sternum retractor fixing device has the advantages that the sternum retractor fixing device is fixed to a sternum retractor through the fast fixing structure, other hands are not needed for holding, manpower waste is reduced, the operation space is increased, and operation is more convenient; the universal supporting rod can be bent, deformed and fixed in the state, and is more convenient and easy to use; meanwhile, the types of the blades can be replaced according to needs, and the functionality is more and stronger.
Owner:BEIJING LUHE HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Catheter-based extracorporeal membrane oxygenation (ECMO)

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.
Owner:VANTIS VASCULAR INC

Interventional valve ring device and interventional valve device

PendingCN121845799AReliable fixed structureEasy to fixAnnuloplasty ringsTricuspid diseaseHeart apex
The invention discloses an interventional valve ring device and an interventional valve device. The interventional valve ring device and the interventional valve device can be used for mitral valve and tricuspid valve lesions. The interventional valve ring device is mainly composed of a valve ring, a valve ring conveying system, a fixing nail and a fixing nail conveying system. The interventional valve is mainly composed of a fixing support, a supporting support, a supporting support covering film and valve leaflets. The interventional valve ring and the interventional valve enter the heart through the interventional delivery system and can pass through the apex of the heart, the femoral vein, the jugular vein or the subclavian vein, the right atrium or the left atrium. The interventional valve is fixed in the interventional valve ring, and a minimally invasive, safe and effective treatment method can be provided for a patient.
Owner:GUANGZHOU YU DOCTOR TEAM MEDICAL TECH CO LTD

A semi-supervised medical image segmentation method based on dual-view complementary consistency

ActiveCN118968091BData setMedicine
The application relates to a semi-supervised medical image segmentation method based on double-view complementary consistency, which only uses a small amount of labeled medical image data to mine potential feature information in a large amount of unlabeled data to improve the segmentation model performance, and comprises the following steps: a feature space distillation mechanism is used to extract and transfer multi-scale semantic features through a teacher-student model; a double-view fusion strategy is used to optimize pseudo labels and optimize the learning effect of the model on unlabeled data; and an uncertainty estimation method assisted by a pre-trained autoencoder is used to optimize the reliability and segmentation precision of the model. Experimental results on a left atrium (LA) and liver tumor segmentation (LiTS) dataset show that the method achieves good effects in terms of segmentation precision and model robustness.
Owner:XINJIANG UNIVERSITY

Intraluminal accessory for atrio-septal shunt dilation, cryoballoon coupling, and blood shielding

PendingUS20260183038A1CatheterRight atrium
An apparatus, system, and method for creating a shunt between a right atrium and a left atrium of a patient's heart. An apparatus includes a shielding structure, a tube proximal to the shielding structure, and an actuating mechanism at a proximal end of the tube. The tube is configured to pass through a lumen of a steerable catheter. The actuating mechanism is for deploying the shielding structure through the tube. The shielding structure is configured for passing through an opening in an atrial septum from the right atrium to the left atrium, and for being retracted in a proximal direction to contact the atrial septum for shielding a proximity of the opening from blood flow in the left atrium to facilitate cryoablation of the opening from the right atrium.
Owner:MEDTRONIC INC