52results about "Bronchi" patented technology

Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. In particular, a variety of embodiments of pulmonary treatment devices are provided. The devices are comprised of a shape memory material wherein the devices are able to be expanded under tension, and then are able to recoil back toward an original relaxed or resting shape as the devices are deployed into the tissue. This action causes the pulmonary treatment devices to corkscrew into damaged tissue, becoming sufficiently entwined to allow pulling of the tissue by retraction of the device. This in turn re-tensions the lung causing lung volume reduction.

The present technology includes an implant for treating excessive central airway collapse (ECAC) of an airway. The implant can comprise a wire-form stent configured to be positioned within the airway. The stent can comprise a C-shaped sidewall, and is configured to be positioned within the airway such that the C-shaped sidewall is positioned proximate a cartilaginous portion of the airway and presses outwardly against the cartilaginous portion.

An endobronchial valve designed for placement in an airway to modify lung volume to a portion of the lung. The valve comprises a frame with a collapsible and expandable configuration, and a valve member made of a flexible material attached to the frame. The valve member includes a distal valve member with a conical shape and nested within a proximal valve member with a frusto-conical shape. The distal valve member features a cavity communicating with an opening at the base, while the proximal valve member has openings of varying diameters. The base of the distal valve member is positioned through the opening of the proximal valve member, allowing for effective modification of lung volume. The valve systems further include a swellable material for changing a fluid flow rate over time to gradually modify lung volume and mitigate complications such as pneumothorax.

The present invention relates to a stent delivery device having: a first support rod into which a first movable body is inserted; a fixed magnet; and a second support rod into which a second movable body is inserted, wherein a first driving magnet included in the first movable body and a second driving magnet included in the second movable body rotate relative to each other by means of the control of an external magnetic field at a predetermined angle around an axis in a first direction with respect to the fixed magnet, thereby separating a first coupling piece and a second coupling piece from a first coupling groove and a second coupling groove and enabling a stent to unfold.

Systems and methods are provided for designing a stent for placement within an airway of a patient. Computer executable instructions are executable by a processor to provide an image segmenter, a graphic user interface, and a model generator. The image segmenter segments at least one image of a region of interest to provide a three-dimensional airway model representing at least a portion of the airway. The graphic user interface prompts a user to select a plurality of locations at an within the airway model and a corresponding plurality of diameters for the plurality of locations. The model generator constructs a stent model from the selected locations and diameters.

Certain embodiments provide a method for controlling airflow in a lung of a respiratory system of a patient. The method generally includes placing a device in an airway passage, wherein the device comprises: an outer wall and an inner wall defining a lumen from a proximal end to a distal end of the device and changing a volume of the lumen over time.

A stent for a respiratory organ includes a bioabsorbable polyester copolymer. The bioabsorbable polyester copolymer is a polyester copolymer having residues of two kinds of ester bond forming monomers as main constituent units, and where the two kinds of ester bond forming monomers are referred to as monomer A and monomer B, respectively, an R value given by the following formula is 0.25 or larger and 0.99 or smaller: R = [AB] / (2[A][B]) 100. In the formula, [A] is a mole fraction (%) of monomer A residues in the polyester copolymer; [B] is a mole fraction (%) of monomer B residues in the polyester copolymer; and [AB] is a mole fraction (%) of structures (A-B and B-A) in which a monomer A residue and a monomer B residue are adjacent to each other in the polyester copolymer.

The present application relates to the technical field of medical devices. An airway stent includes a stent body and a covering film provided on the stent body; the stent body includes a waist stent segment and a dense mesh bare stent segment provided at an end portion of the waist stent segment; the covering film is provided on the waist stent segment; the mesh density of the dense mesh bare stent segment is higher than the mesh density of the waist stent segment. According to the airway stent in the present application, the stimulation of the airway stent to the inner wall of the trachea can be reduced, thereby effectively avoiding the growth of granulation tissue, and preventing the airway lumen from being narrowed again.

Devices, systems, and methods for measuring the diameter of an airway in a human or animal subject are disclosed. The device comprises a flexible catheter body having a proximal end and a distal end. Flexible sizing elements are disposed along and extend approximately orthogonally from the catheter body. The sizing elements have different heights from one another and are configured to fit through the working channel of a bronchoscope. Devices, systems, and methods for redirecting airflow through a lung airway are also disclosed. The method comprises introducing into the airway a catheter comprising a distal end, a proximal end and an elongated portion therebetween, wherein the distal end comprises an airway closing mechanism, and wherein the proximal end comprises an actuator to actuate the airway closing mechanism; and actuating the airway closing mechanism to at least partially close the airway.

The present technology relates to devices, systems and methods for improving lung function in a human individual. The technology includes a robotic system configured to assist in delivery and deployment of an implant in an airway of a patient. The robotic system may include a workstation to engage with and receive instructions from a therapy provider; and an arm in operable communication with the workstation. The arm may include an instrument driver and an articulatable instrument. The articulatable instrument may include an elongate member having a proximal end portion coupled to the instrument driver, a distal end portion configured for positioning in a bronchial airway of the human individual, and a working channel extending from the proximal end portion to the distal end portion. The working channel may be configured to receive a delivery system of an airway implant received therethrough.

A one-way valve for a bronchus, comprising: a support portion, the outer wall of the support portion being used for abutting against the inner wall of a bronchus; and an air-permeable portion provided in the support portion and connected to the inner wall of the support portion. The support portion and the air-permeable portion are of an integrated structure. The technical solution in the prior art of a combination of a nickel-titanium alloy framework and a coating material can be replaced with the present invention, such that the production cost of the one-way valve for a bronchus can be reduced; moreover, the yield of one-way valves for a bronchus can be increased, and the popularization and use of the one-way valves for a bronchus can be facilitated.

Certain embodiments provide a method for controlling airflow in a lung of a respiratory system of a patient. The method generally includes placing a device in an airway passage, wherein the device comprises: an outer wall and an inner wall defining a lumen from a proximal end to a distal end of the device and changing a volume of the lumen over time.

The present invention relates to the technical field of medical devices. An airway stent includes a stent body and a covering film provided on the stent body; the stent body includes a waist stent segment and a dense mesh bare stent segment provided at an end portion of the waist stent segment; the covering film is provided on the waist stent segment; the mesh density of the dense mesh bare stent segment is higher than the mesh density of the waist stent segment. According to the airway stent in the present invention, the stimulation of the airway stent to the inner wall of the trachea can be reduced, thereby effectively avoiding the growth of granulation tissue, and preventing the airway lumen from being narrowed again.

An endoprosthesis configured to shift between a collapsed configuration and an expanded configuration may include a tubular scaffold formed from a single filament knitted about a central longitudinal axis and defining a length from a proximal end to a distal end, the tubular scaffold including a plurality of rows of loops and a plurality of rows of rungs arranged around the central longitudinal axis in an alternating fashion; and a polymeric covering extending along the tubular scaffold. Each row of loops and each row of rungs extends longitudinally along the tubular scaffold between the proximal end and the distal end. The tubular scaffold includes a first cutout region extending along a majority of the length of the tubular scaffold and a second cutout region extending along a majority of the length of the tubular scaffold. The polymeric covering is uninterrupted along the first cutout region and the second cutout region.

Endobrochial implants and delivery systems therefor are disclosed herein. In some embodiments, a delivery system can be used for deploying an implant at a treatment location, where the implant includes a tubular region with one or more interstitial regions. A delivery system can, for example include a flexible elongate member having an implant mounting surface, wherein the implant mounting surface comprises a conformable material configured to adapt to the one or more interstitial regions of the implant when the implant is radially collapsed on the implant mounting surface, thereby engaging the implant. The delivery system can also include a sheath at least partially covering the elongate member, wherein the sheath is movable relative to the elongate member to at least partially expose the implant mounting surface.

The present disclosure provides methods for planning, predictively modeling, and monitoring treatments for lung disease. In some embodiments, a method for planning treatment of a patient having a lung disease includes receiving patient data including computed tomography (CT) data of a lung of the patient. The method may include generating a set of lung metrics by inputting the patient data into a first machine learning algorithm. The method may also include predicting a response of the patient to treatment of the lung disease by inputting the set of lung metrics into a second machine learning algorithm. The method may further include evaluating whether the patient is a candidate for the treatment of the pulmonary disease based on the predicted response. The method may further include evaluating whether the patient is benefited after treatment and whether additional treatment is needed.

Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. In particular, a variety of embodiments of invertible pulmonary treatment devices are provided. The devices are comprised of a shape memory material wherein the devices are able to be expanded under tension, and then are able to recoil back toward an original relaxed or resting shape. In these embodiments, a portion of the device is invertible. Thus, each device is able to store energy at least in the inversion, wherein the energy is utilized to continually tension the lung as the device relaxes toward its original shape.

A tool for removing and / or displacing a foreign body in a patient's body, comprising: a sleeve element (40) comprising a proximal end, a distal end and a central axis, wherein the sleeve element (40) comprises a tubular body defining an inner lumen (42) and is movable in the proximal and distal direction; an operative part (160) comprising a proximal end, a distal end and a central axis generally coaxial to the central axis of the sleeve element (40): a stabilizer which has a proximal end and a distal end; a plurality of intervention elements (166), each comprising a proximal end and a distal end; wherein the majority of engagement elements (166) are connected to the stabilizer and extend distally from the distal end of the stabilizer, wherein the engagement elements (166) are configured such that they transition between an open and a closed configuration in response to a force acting on the engagement elements (166), wherein the distal ends of the engagement elements (166) are configured such that they move away from the central axis of the operative part (160) when transitioning from the closed to the open configuration; and one or more grip elements (167) arranged on the stabilizers, extending from the engagement elements (166) to the central axis of the operative part (160) when the engagement elements (166) are in a closed configuration, wherein the sleeve element (40) comprises a plurality of secondary conduits (243), each of the secondary conduits (243) having a proximal and a distal end, and wherein the tool further comprises a pressure element (46) which includes a plurality of compression wires (146), wherein at least a part of each of the compression wires (146) is contained in the plurality of secondary lines (243), wherein each of the compression wires (146) has a proximal end and a distal end, wherein the compression wires (146) are configured such that they transition between an extended and a contracted configuration.

The present technology is directed to devices, systems, and methods for improving pulmonary function in a human subject. The present technology includes a robotic system configured to assist in delivery and deployment of an implant in an airway of a patient. The robotic system can comprise a workstation for engaging with and receiving instructions from a treatment provider and an arm in operative communication with the workstation. The arm can comprise an instrument driver and an articulatable instrument. The articulatable instrument can comprises an elongate member having a proximal portion coupled to the instrument driver, a distal portion configured for positioning in a bronchial airway of the human subject, and a working channel extending from the proximal portion to the distal portion. The working channel can be configured to receive a delivery system containing the airway implant therethrough.

A bronchial flow control device comprises a tubular body comprising struts extending between first and second ends, the struts being expandable between radially contracted and expanded shapes, a valve disposed proximate the second end, a membrane covering the struts, and microfibers on the membrane. A method comprises attaching a bronchial valve to a delivery catheter in an unexpanded state, inserting the bronchial valve into an airway, actuating the delivery catheter to radially expand the bronchial valve, pushing microfibers into an anatomic duct wall, detaching the delivery catheter from the bronchial valve, and withdrawing the delivery catheter from the airway. A delivery system for a valve comprises a handle, a first actuator to control a rotational position of a first coupler, a second actuator to control a radial position of a second coupler, and a third actuator to control an axial position between the first and second couplers.

The present technology includes an implant for treating excessive central airway collapse (EC AC) of an airway. The implant can comprise a wire-form stent configured to be positioned within the airway. The stent can comprise a C-shaped sidewall, and is configured to be positioned within the airway such that the C-shaped sidewall is positioned proximate a cartilaginous portion of the airway and presses outwardly against the cartilaginous portion.

Certain embodiments provide a method for controlling airflow in a lung of a respiratory system of a patient. The method generally includes placing a device in an airway passage, wherein the device comprises: an outer wall and an inner wall defining a lumen from a proximal end to a distal end of the device and changing a volume of the lumen over time.

An airway support device of the present disclosure can be attached to tracheal and / or bronchial cartilage on opposing sides of a tracheal and / or bronchial wall to pull the tracheal and / or bronchial cartilages toward each other to reconstruct and / or reshape to a normal anatomy across the membranous tracheal and / or bronchial wall and thus relieving tension across the tracheal and / or bronchial wall. The airway support device can include at least two longitudinal strips that extend longitudinally along and are attached (e.g,, sutured) to the trachea and / or bronchus on opposite sides of the tracheal and / or bronchial wall. Pairs of lateral strips extending from each of the longitudinal strips can be attached to each other under tension. The tracheal and / or bronchial wall can be attached (e.g., sutured) to the lateral strips to open the airway of the trachea and / or bronchus.

The application belongs to the technical field of medical devices, and is a kind of airway stent, comprising a stent body and a covering film arranged on the stent body, characterized in that the stent body comprises a fixed stent section and a movable stent section arranged at the end of the fixed stent section, and the covering film is arranged on the fixed stent section; at least one movable part in the form of an opening is arranged on the movable stent section, and the radial dimension of the movable stent section is greater than that of the fixed stent section. According to the airway stent in the application, the movable stent section with a radial dimension greater than that of the fixed stent section is arranged to increase the anchoring force of the airway stent, so that the airway stent is not prone to displacement, and the movable part in the form of an opening is arranged to increase the deformation space of the movable stent section, reduce the stimulation of the airway stent to the inner wall of the airway, and prevent the growth of granulation tissue.

Technologies as described herein are directed towards generating optimized stent designs for treatment of tubular anatomical structures. In an exemplary computing system, the system obtains imaging data comprising images representative of anatomical structures. The system then generates a plurality of models based upon the imaging data. The models are then clustered based upon similar characteristics of the models. Certain fit parameters are applied to the models in each cluster and an optimized stent shape is generated for each cluster, wherein each optimized stent shape is representative of the models within the cluster.

A respiratory stent comprising a bioabsorbable polyester copolymer, the bioabsorbable polyester copolymer being a polyester copolymer having two types of ester bond-forming monomer residues as main constituent units, and when the two types of ester bond-forming monomers are monomer A and monomer B, respectively, the R value represented by the following formula is 0.25 to 0.99: R=[AB] / (2[A][B])×100, in which [A] is the molar fraction (%) of monomer A residue in the polyester copolymer, [B] is the molar fraction (%) of monomer B residue in the polyester copolymer, and [AB] is the molar fraction (%) of a structure (AB and BA) in which a monomer A residue and a monomer B residue are adjacent to each other in the polyester copolymer.

Apparatus (20) is provided for use with a guidewire (12). The apparatus includes a guide tube (22) having a guidewire-engaging portion (122) and a slit (28) extending proximally along a wall of the guide tube, from a distal end (32) of the tube, a proximal end (29) of the slit being located distally to a proximal end (30) of the tube. A first stent (52) surrounds the tube and is advanceable together with the tube into a lumen of a subject, the first stent being slidably advanceable off the distal end of the tube; and a second stent (54), proximal to the first stent, surrounding a proximal portion of the tube, and advanceable off the distal end of the tube into the lumen, and placed alongside the first stent subsequently to advancement of the first stent off the distal end of the tube. Other applications are also described.

The present application relates to a method of using a self-adjusting stent assembly and a kit comprising the same. A method of using a self-adjusting stent assembly, comprising: estimating a body lumen diameter associated with a portion of a body lumen in which the stent assembly is to be placed; determining a target expanded stent diameter of the stent assembly to be placed in the portion of the body lumen based on the estimated diameter; selecting a stent assembly for stent implantation of the portion of the body lumen, wherein the stent assembly is configured to expand from an initial diameter to an expanded diameter within an expanded diameter range; wherein the expanded diameter range is from about 9 mm to about 5.5 mm; and wherein the target expanded stent diameter is within the expanded diameter range; and applying a persistent radial force to a wall of the portion of the lumen, wherein the radial force is less than about 0.33 N / mm.

The application relates to an implant, a conveying mechanism, a lung volume reduction implant device and system, the lung volume reduction implant device comprising an implant and a conveying mechanism, the conveying mechanism being arranged to controllably release or recover the implant; the implant comprising a proximal end, a distal end and an intermediate section, the intermediate section being capable of being deformed between a coiled shape and a straightened shape; the conveying mechanism comprising a pushing part and a first connecting part connected with the pushing part, the first connecting part being detachably connected with the proximal end. The application can block the bronchus, the contraction stress area of the implant is complete, and the success rate of the lung volume reduction surgery is effectively improved. A plurality of implants do not need to be implanted, and the burden on the patient is further reduced. The implant and the conveying mechanism are detachably connected, the implant can be loosened in situ, the implant does not need to be pushed forward, and precise release is achieved.

The invention relates to prosthesis for treating pulmonary fibrosis, in particular, idiopathic pulmonary fibrosis (IPF), and a method for treating pulmonary fibrosis, in particular, idiopathic pulmonary fibrosis (IPF).