78results about "Bronchi" patented technology

Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. In particular, a variety of embodiments of pulmonary treatment devices are provided. The devices are comprised of a shape memory material wherein the devices are able to be expanded under tension, and then are able to recoil back toward an original relaxed or resting shape as the devices are deployed into the tissue. This action causes the pulmonary treatment devices to corkscrew into damaged tissue, becoming sufficiently entwined to allow pulling of the tissue by retraction of the device. This in turn re-tensions the lung causing lung volume reduction.

Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. In particular, a variety of embodiments of pulmonary treatment devices are provided. The devices are comprised of a shape memory material wherein the devices are able to be expanded under tension, and then are able to recoil back toward an original relaxed or resting shape as the devices are deployed into the tissue. This action causes the pulmonary treatment devices to corkscrew into damaged tissue, becoming sufficiently entwined to allow pulling of the tissue by retraction of the device. This in turn re-tensions the lung causing lung volume reduction.

The present technology includes an implant for treating excessive central airway collapse (ECAC) of an airway. The implant can comprise a wire-form stent configured to be positioned within the airway. The stent can comprise a C-shaped sidewall, and is configured to be positioned within the airway such that the C-shaped sidewall is positioned proximate a cartilaginous portion of the airway and presses outwardly against the cartilaginous portion.

An endobronchial valve designed for placement in an airway to modify lung volume to a portion of the lung. The valve comprises a frame with a collapsible and expandable configuration, and a valve member made of a flexible material attached to the frame. The valve member includes a distal valve member with a conical shape and nested within a proximal valve member with a frusto-conical shape. The distal valve member features a cavity communicating with an opening at the base, while the proximal valve member has openings of varying diameters. The base of the distal valve member is positioned through the opening of the proximal valve member, allowing for effective modification of lung volume. The valve systems further include a swellable material for changing a fluid flow rate over time to gradually modify lung volume and mitigate complications such as pneumothorax.

The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment. The invention further discloses a catheter with a transparent occlusion element at its tip that enables examination of the lung passageway through a viewing scope.

The present invention relates to a stent delivery device having: a first support rod into which a first movable body is inserted; a fixed magnet; and a second support rod into which a second movable body is inserted, wherein a first driving magnet included in the first movable body and a second driving magnet included in the second movable body rotate relative to each other by means of the control of an external magnetic field at a predetermined angle around an axis in a first direction with respect to the fixed magnet, thereby separating a first coupling piece and a second coupling piece from a first coupling groove and a second coupling groove and enabling a stent to unfold.

Systems and methods are provided for designing a stent for placement within an airway of a patient. Computer executable instructions are executable by a processor to provide an image segmenter, a graphic user interface, and a model generator. The image segmenter segments at least one image of a region of interest to provide a three-dimensional airway model representing at least a portion of the airway. The graphic user interface prompts a user to select a plurality of locations at an within the airway model and a corresponding plurality of diameters for the plurality of locations. The model generator constructs a stent model from the selected locations and diameters.

Certain embodiments provide a method for controlling airflow in a lung of a respiratory system of a patient. The method generally includes placing a device in an airway passage, wherein the device comprises: an outer wall and an inner wall defining a lumen from a proximal end to a distal end of the device and changing a volume of the lumen over time.

The invention provides an instrument device which is used for lung volume reduction and relates to the technical field of medical instruments, the instrument device comprises a core wire and an elastic implant, and the core wire is movably arranged in the elastic implant in a penetrating mode; the far end of the core wire comprises a far-end rigid section and a far-end flexible section, and the far-end rigid section is farther away from the near end of the core wire than the far-end flexible section; when the core wire moves in the elastic implant body, when the far-end rigid section is subjected to the acting force of the elastic implant body, the far-end flexible section adjusts the position of the far-end rigid section in the elastic implant body through deformation, so that the elastic implant body is formed. The core wire is arranged in the elastic implant, so that the axis of the core wire in the elastic implant is close to the axis of the elastic implant. Through the instrument provided by the invention, the problems that the core wire is difficult to penetrate into the elastic implant and is easy to penetrate out of the cutting groove of the elastic implant are solved.

A stent for a respiratory organ includes a bioabsorbable polyester copolymer. The bioabsorbable polyester copolymer is a polyester copolymer having residues of two kinds of ester bond forming monomers as main constituent units, and where the two kinds of ester bond forming monomers are referred to as monomer A and monomer B, respectively, an R value given by the following formula is 0.25 or larger and 0.99 or smaller: R = [AB] / (2[A][B]) 100. In the formula, [A] is a mole fraction (%) of monomer A residues in the polyester copolymer; [B] is a mole fraction (%) of monomer B residues in the polyester copolymer; and [AB] is a mole fraction (%) of structures (A-B and B-A) in which a monomer A residue and a monomer B residue are adjacent to each other in the polyester copolymer.

The present application relates to the technical field of medical devices. An airway stent includes a stent body and a covering film provided on the stent body; the stent body includes a waist stent segment and a dense mesh bare stent segment provided at an end portion of the waist stent segment; the covering film is provided on the waist stent segment; the mesh density of the dense mesh bare stent segment is higher than the mesh density of the waist stent segment. According to the airway stent in the present application, the stimulation of the airway stent to the inner wall of the trachea can be reduced, thereby effectively avoiding the growth of granulation tissue, and preventing the airway lumen from being narrowed again.

An implantable artificial bronchus including a body having a proximal upper opening and a distal lower opening. The distal lower opening being in fluid communication with the proximal upper opening, and the body at least partially tapering along a length toward the distal lower opening. The body having a plurality of side openings configured to allow air to enter into and exit the implantable artificial bronchus through the body. A length of the body is greater than 4 times the size of a largest diameter of the body, and the diameter of the proximal upper opening is larger than a diameter of the distal lower opening.

Devices, systems, and methods for measuring the diameter of an airway in a human or animal subject are disclosed. The device comprises a flexible catheter body having a proximal end and a distal end. Flexible sizing elements are disposed along and extend approximately orthogonally from the catheter body. The sizing elements have different heights from one another and are configured to fit through the working channel of a bronchoscope. Devices, systems, and methods for redirecting airflow through a lung airway are also disclosed. The method comprises introducing into the airway a catheter comprising a distal end, a proximal end and an elongated portion therebetween, wherein the distal end comprises an airway closing mechanism, and wherein the proximal end comprises an actuator to actuate the airway closing mechanism; and actuating the airway closing mechanism to at least partially close the airway.

The present technology relates to devices, systems and methods for improving lung function in a human individual. The technology includes a robotic system configured to assist in delivery and deployment of an implant in an airway of a patient. The robotic system may include a workstation to engage with and receive instructions from a therapy provider; and an arm in operable communication with the workstation. The arm may include an instrument driver and an articulatable instrument. The articulatable instrument may include an elongate member having a proximal end portion coupled to the instrument driver, a distal end portion configured for positioning in a bronchial airway of the human individual, and a working channel extending from the proximal end portion to the distal end portion. The working channel may be configured to receive a delivery system of an airway implant received therethrough.

A one-way valve for a bronchus, comprising: a support portion, the outer wall of the support portion being used for abutting against the inner wall of a bronchus; and an air-permeable portion provided in the support portion and connected to the inner wall of the support portion. The support portion and the air-permeable portion are of an integrated structure. The technical solution in the prior art of a combination of a nickel-titanium alloy framework and a coating material can be replaced with the present invention, such that the production cost of the one-way valve for a bronchus can be reduced; moreover, the yield of one-way valves for a bronchus can be increased, and the popularization and use of the one-way valves for a bronchus can be facilitated.

Certain embodiments provide a method for controlling airflow in a lung of a respiratory system of a patient. The method generally includes placing a device in an airway passage, wherein the device comprises: an outer wall and an inner wall defining a lumen from a proximal end to a distal end of the device and changing a volume of the lumen over time.

The present invention relates to the technical field of medical devices. An airway stent includes a stent body and a covering film provided on the stent body; the stent body includes a waist stent segment and a dense mesh bare stent segment provided at an end portion of the waist stent segment; the covering film is provided on the waist stent segment; the mesh density of the dense mesh bare stent segment is higher than the mesh density of the waist stent segment. According to the airway stent in the present invention, the stimulation of the airway stent to the inner wall of the trachea can be reduced, thereby effectively avoiding the growth of granulation tissue, and preventing the airway lumen from being narrowed again.

An endoprosthesis configured to shift between a collapsed configuration and an expanded configuration may include a tubular scaffold formed from a single filament knitted about a central longitudinal axis and defining a length from a proximal end to a distal end, the tubular scaffold including a plurality of rows of loops and a plurality of rows of rungs arranged around the central longitudinal axis in an alternating fashion; and a polymeric covering extending along the tubular scaffold. Each row of loops and each row of rungs extends longitudinally along the tubular scaffold between the proximal end and the distal end. The tubular scaffold includes a first cutout region extending along a majority of the length of the tubular scaffold and a second cutout region extending along a majority of the length of the tubular scaffold. The polymeric covering is uninterrupted along the first cutout region and the second cutout region.

A method for treating a patient's airway by coupling a deployment device to a bronchoscope at the working channel is disclosed. The coupling of such can hold the deployment device in a fixed position and allow for the precise placement of small airway stents within the lungs of a patient by a single practitioner. The fixed position may be adjustable over a range.

Endobrochial implants and delivery systems therefor are disclosed herein. In some embodiments, a delivery system can be used for deploying an implant at a treatment location, where the implant includes a tubular region with one or more interstitial regions. A delivery system can, for example include a flexible elongate member having an implant mounting surface, wherein the implant mounting surface comprises a conformable material configured to adapt to the one or more interstitial regions of the implant when the implant is radially collapsed on the implant mounting surface, thereby engaging the implant. The delivery system can also include a sheath at least partially covering the elongate member, wherein the sheath is movable relative to the elongate member to at least partially expose the implant mounting surface.

The present disclosure provides methods for planning, predictively modeling, and monitoring treatments for lung disease. In some embodiments, a method for planning treatment of a patient having a lung disease includes receiving patient data including computed tomography (CT) data of a lung of the patient. The method may include generating a set of lung metrics by inputting the patient data into a first machine learning algorithm. The method may also include predicting a response of the patient to treatment of the lung disease by inputting the set of lung metrics into a second machine learning algorithm. The method may further include evaluating whether the patient is a candidate for the treatment of the pulmonary disease based on the predicted response. The method may further include evaluating whether the patient is benefited after treatment and whether additional treatment is needed.

Pulmonary treatment devices, systems and methods of use are provided which take into account the vast tissue damage of advanced COPD sufferers and provide treatments designed specifically to treat the particularly compromised lung tissues that are present in these patients. These treatments reduce trapped air volume, tension lung tissue and enhance lung elastic recoil. In particular, a variety of embodiments of invertible pulmonary treatment devices are provided. The devices are comprised of a shape memory material wherein the devices are able to be expanded under tension, and then are able to recoil back toward an original relaxed or resting shape. In these embodiments, a portion of the device is invertible. Thus, each device is able to store energy at least in the inversion, wherein the energy is utilized to continually tension the lung as the device relaxes toward its original shape.

A tool for removing and / or displacing a foreign body in a patient's body, comprising: a sleeve element (40) comprising a proximal end, a distal end and a central axis, wherein the sleeve element (40) comprises a tubular body defining an inner lumen (42) and is movable in the proximal and distal direction; an operative part (160) comprising a proximal end, a distal end and a central axis generally coaxial to the central axis of the sleeve element (40): a stabilizer which has a proximal end and a distal end; a plurality of intervention elements (166), each comprising a proximal end and a distal end; wherein the majority of engagement elements (166) are connected to the stabilizer and extend distally from the distal end of the stabilizer, wherein the engagement elements (166) are configured such that they transition between an open and a closed configuration in response to a force acting on the engagement elements (166), wherein the distal ends of the engagement elements (166) are configured such that they move away from the central axis of the operative part (160) when transitioning from the closed to the open configuration; and one or more grip elements (167) arranged on the stabilizers, extending from the engagement elements (166) to the central axis of the operative part (160) when the engagement elements (166) are in a closed configuration, wherein the sleeve element (40) comprises a plurality of secondary conduits (243), each of the secondary conduits (243) having a proximal and a distal end, and wherein the tool further comprises a pressure element (46) which includes a plurality of compression wires (146), wherein at least a part of each of the compression wires (146) is contained in the plurality of secondary lines (243), wherein each of the compression wires (146) has a proximal end and a distal end, wherein the compression wires (146) are configured such that they transition between an extended and a contracted configuration.

To provide devices, systems and methods for improving airflow within an airway.SOLUTION: One example embodiment includes a method for treating a subject. The method includes (1) placing an expandable object into one or more airways of the bronchial tree of the subject, (2) expanding the expandable object within at least one of the one or more airways such that at least a portion of a wall of the one or more airways is expanded, and (3) placing a stent in the airway such that a portion of the stent is adjacent to the portion of the wall of the one or more expanded airways.SELECTED DRAWING: Figure 8

The present application relates to a system for improving airflow within the bronchial tree of an emphysematous lung. The system comprises: a delivery device; and an implantable object comprising a distal end and a proximal end. The implantable object is configured to: place the implantable object through multiple generations of connected airways using the delivery device such that the distal end is placed in a first airway within a terminal portion of the bronchial tree and the proximal end is placed in a second airway within a mid-portion of the bronchial tree; and, when placing the implantable object through the multiple generations of connected airways, expand the implantable object such that at least a portion of the multiple generations of connected airways expands from (i) an initial diameter prior to placement of the implantable object to (ii) an expanded diameter that is greater than the initial diameter.

The present technology is directed to devices, systems, and methods for improving pulmonary function in a human subject. The present technology includes a robotic system configured to assist in delivery and deployment of an implant in an airway of a patient. The robotic system can comprise a workstation for engaging with and receiving instructions from a treatment provider and an arm in operative communication with the workstation. The arm can comprise an instrument driver and an articulatable instrument. The articulatable instrument can comprises an elongate member having a proximal portion coupled to the instrument driver, a distal portion configured for positioning in a bronchial airway of the human subject, and a working channel extending from the proximal portion to the distal portion. The working channel can be configured to receive a delivery system containing the airway implant therethrough.

The invention relates to a covered stent and a conveying method thereof. The covered stent is a tubular stent, the peripheral face of the covered stent is provided with a first area and a second area, the second area penetrates through the covered stent in the target direction, and the target direction refers to the direction from the first axial end to the second axial end of the covered stent; the covered stent comprises a stent body and a covering film, the stent body is arranged in the first area, and the covering film is at least arranged in the first area to cover the stent body. The covered stent can be applied to ureters, esophagus and other natural cavities needing wriggling, axial displacement does not occur during wriggling of the natural cavities, granulation can be prevented from growing towards the interior of the covered stent, and then the covered stent can be prevented from being narrowed again; the covered stent can also be applied to natural tracts such as trachea and bronchus, so that fluff on the inner wall of the natural tracts is in contact with foreign matters in the natural tracts in the second area of the covered stent, and the foreign matters in the natural tracts can be discharged.

An implantable artificial bronchus (IAB) is provided that is used for the treatment of chronic obstructive pulmonary diseases, such as pulmonary emphysema. The implantable artificial bronchus can be made with silicone or nitinol, and has a tapered cylindrical shape. Additional embodiments of this apparatus may be further associated with a one-way valve on the nozzle of the IAB.

A bronchial flow control device comprises a tubular body comprising struts extending between first and second ends, the struts being expandable between radially contracted and expanded shapes, a valve disposed proximate the second end, a membrane covering the struts, and microfibers on the membrane. A method comprises attaching a bronchial valve to a delivery catheter in an unexpanded state, inserting the bronchial valve into an airway, actuating the delivery catheter to radially expand the bronchial valve, pushing microfibers into an anatomic duct wall, detaching the delivery catheter from the bronchial valve, and withdrawing the delivery catheter from the airway. A delivery system for a valve comprises a handle, a first actuator to control a rotational position of a first coupler, a second actuator to control a radial position of a second coupler, and a third actuator to control an axial position between the first and second couplers.

The present technology includes an implant for treating excessive central airway collapse (EC AC) of an airway. The implant can comprise a wire-form stent configured to be positioned within the airway. The stent can comprise a C-shaped sidewall, and is configured to be positioned within the airway such that the C-shaped sidewall is positioned proximate a cartilaginous portion of the airway and presses outwardly against the cartilaginous portion.