198 results about "Bronchial tubes" patented technology

The invention belongs to the technical field of medical imaging and digital twinning, and discloses a thoracic cavity whole organ system level lung four-dimensional EIT detection digital motif and a library building method, and the method comprises the following steps: S1) segmenting multiple organs such as double lungs, heart, sternum, rib and thoracic vertebra central axis skeleton, main bronchus and esophagus based on an individual CT image, and building a three-dimensional geometric model integrated with an EIT electrode array; s2) simulating breathing dynamic deformation by using a solid mechanical model; s3) establishing a coupling relationship between deformation and conductivity, and generating dynamic three-dimensional conductivity distribution; s4) solving an electromagnetic field positive problem, and generating a virtual EIT voltage database synchronous with respiration; the invention also covers pathological model integration and data enhancement strategies. According to the method, a high-fidelity, large-scale and diversified EIT virtual data set can be generated, core data support is provided for training and verifying an AI intelligent reconstruction algorithm, and a model foundation is laid for developing a lung function dynamic digital twinning system.

The invention discloses a variable-rigidity flexible conformal interventional surgical robot which comprises a flexible continuum, a driving device and a guide translation device. The flexible continuum is composed of a continuum body, a driving wire group and a variable rigidity assembly; the driving device comprises four driving motors arranged on the bracket; the guide translation device comprises a translation mechanism and a guide mechanism which are arranged on the underframe; according to the surgical robot, the flexible continuum serves as a main body, the continuum body is high in flexibility, large in bending degree, high in stability and capable of adapting to the structural characteristics that the lung bronchus is high in bending degree and complex in bending shape, and dynamic adjustment of large-bending intervention and conformal locking is achieved by being matched with the variable-rigidity assembly; the detection assembly at the front end of the flexible continuum meets operation requirements; the driving device is matched with the guide translation device, so that synchronous adjustment is realized according to an intervention path, and an intervention operation is accurately, stably and safely completed.

The invention discloses a biological nitrogen and phosphorus removal MBR sewage treatment system and a treatment process thereof. The process comprises the following steps: 1) pretreatment; 2) treatment in an anaerobic tank; (3) treating in an anoxic tank; 4) treatment in an aerobic tank; 5) MBR membrane pool treatment; sewage enters the box body through the water inlet, the moving mechanism drives the aeration mechanism and the scum cleaning mechanism to move, the aeration mechanism performs aeration treatment on the sewage in the box body, and when the aeration mechanism blows gas into the sewage through the branch gas pipe, bubbles can be scattered by spiral blades, so that the contact area between the gas and liquid is further increased, and the aeration effect is enhanced; when the sewage is subjected to aeration treatment, the scum after aeration treatment rises, the scum cleaning mechanism scrapes the scum floating after aeration for multiple times, collects the scraped scum and sends the scum out of the box body, impurities suspended in the middle layer of the sewage are fished, and the sewage after scum cleaning enters the next treatment procedure through the water outlet.

The utility model discloses an integrated bronchus plugging catheter which comprises a tracheal catheter, a connector connected to the front end of the tracheal catheter and a bronchus catheter penetrating out of the tracheal catheter, and a partition wall extending in the length direction of the tracheal catheter is arranged in the tracheal catheter. The space in the tracheal catheter is divided into a first cavity and a fourth cavity by the partition wall, a bronchoscope or a drainage tube or a sputum suction tube is inserted into the fourth cavity, the bronchial catheter penetrates through the first cavity, a second blocking sleeve bag is fixed to the tail end, penetrating out of the first cavity, of the bronchial catheter, and a first blocking sleeve bag is fixed to the outer portion of the rear end of the tracheal catheter. Due to the fact that the bronchial catheter is limited in the first cavity, when a bronchoscope and the like are inserted into the fourth cavity, interference of the bronchial catheter is avoided; a minimum space enough to guarantee normal use of the bronchial catheter can be reserved according to the size of the bronchial catheter, so that sufficient space is reserved for insertion of a bronchoscope, a drainage tube, a sputum suction tube and the like, and smooth insertion of diagnosis and treatment equipment is guaranteed.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses a cyclophosphamide ternary nano-micelle and a preparation method thereof.The cyclophosphamide ternary nano-micelle prepared through the method can be used for treating malignant lymphoma, multiple myeloma, leukemia, breast cancer, ovarian cancer, cervical cancer, prostatic cancer, colon cancer, bronchial cancer, lung cancer and the like. Reasonable preparation steps and a preparation formula are adopted, the use of an organic reagent is reduced, the irritation of cyclophosphamide is reduced and the stability of the micelle is improved by adjusting a freeze-drying technology, and the cyclophosphamide micelle adopts amphiphilic macromolecules as a carrier material, so that the drug loading capacity and the stability of the micelle are obviously improved, and the bioavailability of the micelle is improved. The ternary nano-micelle system has the advantages that the solubility of cyclophosphamide is improved, the in-vivo bioavailability is increased, the preparation method is simple, the micelle performance is stable, and large-scale industrial production is facilitated.

Apparatus and methods for deactivating bronchial nerves and ablating smooth muscle extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits ultrasound so as to heat tissues throughout a relatively large impact volume (13) to a temperature sufficient to inactivate nerve conduction and ablate smooth muscle but insufficient to cause rapid ablation or necrosis of the surrounding tissues. The treatment can be performed without locating or focusing on individual bronchial nerves or smooth muscle.

Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4 / 5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.

The invention discloses a plastic suction flushing tube used in cooperation with a visual double-lumen bronchial catheter, the plastic suction flushing tube comprises a suction flushing tube, the suction flushing tube comprises a plastic part and an operation part, the plastic part is located at the far end of the suction flushing tube, a built-in steel wire is arranged at the position 1-1.5 cm away from a hole in the far end of the suction flushing tube, and the operation part is located in the plastic part. The built-in steel wire enables the plastic part to be bent at will and to be kept shaped; the shape of the front end of the suction and flushing pipe can be flexibly adjusted, the suction and flushing pipe can be accurately guided to a target suction or flushing area, the suction and flushing accuracy is improved, the risk that sputum or secretions are not thoroughly removed is reduced, complications such as respiratory tract blockage are reduced, and the life safety of a patient is guaranteed.

The invention relates to the technical field of administration catheters, and discloses a neonatal intratracheal administration catheter, which comprises an administration catheter and an active agent liquid bottle placed on a suspension bracket, one end of the administration catheter is fixedly provided with an end tube extending into a bronchus, the end tube is provided with a respiration switching cylinder, and the respiration switching cylinder is internally provided with a telescopic cavity. After expiration is completed, the newborn begins to inhale, at the moment, a lifting plug body drives the lifting plug body to move towards a first baffle ring under the action of suction force and blocks a side hole again, and at the moment, a communicating hole is in an open state; therefore, the newborn can directly suck outside air through the air suction hose, at the moment, negative pressure cannot be generated in the telescopic cavity, the leakage-proof film cannot be opened, meanwhile, in the air suction process, a liquid active agent originally located in the lifting plug body can be sucked into the lung along with the air, and the effect that the active agent is sprayed to the lung is achieved.

A phosphodiesterase type 5 inhibitor is used in the preparation of a medicament for resisting fibrotic diseases. Experiments in animal models of ischemia-reperfusion (UIRI)-induced renal fibrosis, unilateral ureteral obstruction (UUO)-caused kidney fibrosis and idiopathic pulmonary fibrosis show that a PDE5 inhibitor such as tadalafil, sildenafil and vardenafil can significantly inhibit the expression of multiple fibrosis iconic proteins such as fibronectin, collagen I, renal injury molecule-1, and α-skeletal muscle actin in UIRI and UUO renal fibrosis lesions, improves glomerulopathy, degree of renal tubular distension, renal interstitial collagen fiber deposition and inflammatory cell infiltration, reduces the fibrotic area within the lesion, and significantly inhibits the progression of renal fibrosis; and the PDE5 inhibitor can significantly improve smooth muscle proliferation and inflammatory cell infiltration in bronchioles and pulmonary arterioles of idiopathic pulmonary fibrosis lesion, improve damage condition of alveolar tissue, and significantly inhibit the progression of pulmonary fibrosis.

A catheter driving system is configured to navigate various medical catheters through complex narrow tissue openings or between organs and tissue planes, which may include lung bronchi pathway openings of 3 millimeters or less. These catheters may comprise one or more sections and optional steering cables. The catheter driving device comprises at least one rotary actuator configured to rotate at least one region of the catheter and at least one steering cable actuator configured to apply flexing force to control the direction of the catheter. To prevent the rotary actuator from tangling the steering cables, the system is further configured to rotate at least one steering cable along with the rotation of the rotated catheter region. This cable rotation may be 1:1 (e.g., synchronously) with the catheter rotation or may be configured to vary somewhat to accommodate catheter twisting, spring action, windup, and other effects.

The utility model relates to the technical field of medical instruments, in particular to a steering tracheal catheter which comprises a main catheter body, the head end of the main catheter body is connected with a standard connector, the standard connector is used for being connected with a breathing machine, an air bag I is arranged on the outer wall of the tail of the main catheter body and connected with an inflation adjusting mechanism I, and the inflation adjusting mechanism I is used for adjusting the inflation adjusting mechanism. A steering tube section is arranged at the head part of the main catheter, and after the main catheter is placed into a trachea and / or a bronchus of a human body, the steering tube section is positioned outside the mouth or the nose of the human body, so that the steering tube section can steer at will outside the mouth or the nose of the human body. According to the utility model, the steering tube section is arranged at the head part of the main catheter, and after the main catheter is placed into the trachea and / or the bronchus of the human body, the steering tube section is positioned outside the mouth or the nose of the human body and can steer at will outside the mouth or the nose of the human body; the part, located outside the mouth or the nose of the human body, of the tracheal catheter is prevented from being bent.

The invention discloses an anti-reflux spray type trachea cannula integrated with a power device and an airway surface anesthesia method.The anti-reflux spray type trachea cannula comprises a trachea cannula device, a spray power device and a medicine bottle, the trachea cannula device comprises a trachea cannula body and a spray assembly, and the spray assembly comprises a spray head, a spray connecting pipe and a spray connector; the spray head is arranged in the trachea cannula body and located at the end inserted into the human body, one end of the spray connecting pipe is connected with the spray connector, and the other end is connected with the spray head. The suction end of the spray power device is connected with the medicine bottle, and the discharge end is connected with the spray joint; when the trachea cannula is inserted into and pulled out of a patient, anesthetic liquid medicine in the medicine bottle is conveyed to the spraying head through the spraying power device to be sprayed out for surface anesthesia, so that the occurrence of violent stress reaction during cannula insertion and cannula pulling can be effectively reduced; the occurrence rate of complications such as bucking, laryngeal spasm, tracheal spasm, bronchus spasm, blood pressure drastic increase and arrhythmia is remarkably reduced, and the safety and comfort of a patient are effectively improved.

The utility model discloses a kind of reusable bronchial endoscope handle, including first shell, second shell and rotating mechanism, first shell and second shell are connected with lid and constitute handle cavity, and the pipe end of handle cavity is provided with insertion tube;Rotating mechanism has rotating wheel and axial pull switch being set on rotating wheel, rotating wheel is set in handle cavity, axial pull switch is set to the outside of first shell and / or second shell, rotating wheel is axially rotated and is connected by traction line and drives insertion tube swing.Equipped with axial pull switch on the outer surface of shell and fixedly connected with the output shaft of rotating wheel in this way, and then drive rotating wheel to axially rotate and drive insertion tube swing, can be exempted from to open shell hole in the side of two shells, and then improve the overall waterproof effect of bronchial endoscope handle, improve service life, and cleaning is more convenient, bronchial endoscope handle can be reused multiple times, save resources, reduce medical cost.

The invention discloses a tracheostomy tube for assisting cough of a patient, and relates to the technical field of medical instruments, the tracheostomy tube comprises a catheter, one end of the catheter inserted into the tracheostomy tube is provided with an inflatable and deflatable air bag, and one end of the catheter located outside the tracheostomy tube is provided with a foldable baffle. And a one-way valve capable of feeding air into the guide pipe is arranged on the guide pipe at the end. According to the device, a patient can be assisted in cough action, a low-resistance release path is provided for high-pressure and high-speed airflow generated in the suffocation stage before cough, the effect that the glottis is suddenly opened due to pressure during natural cough is simulated, and therefore secretions in the trachea and the bronchus are more effectively removed.

An automatic control system for a tracheobronchial pneumatic stimulator (10) intended to be connected to a subject, the stimulator (10) comprising: a pressure unit (13) configured to generate a set of negative pressure pulses during a relaxation exhalation of the subject, each pulse corresponding to an output of the pressure unit (13); and a connection assembly (11, 12) configured to connect the pressure unit (13) to the subject's respiratory system. The control system comprises: a pressure sensor (15) configured to measure an internal negative pressure (P) applied to the subject's respiratory system corresponding to each pulse after it is generated by the pressure unit (13); a calculation module (32) configured to compare in real time the absolute value of the measured internal negative pressure (P) with a predetermined threshold (S) and, based on the comparison result, determine an updated output value to be applied to the pressure unit (13) such that the absolute value of the subsequent internal negative pressure (P) corresponding to the updated output value is less than the absolute value of the threshold (S); and a control module (33) configured to apply the updated output value to the pressure unit (13) before the generation of the next pulse.

This invention discloses a method and system for boundary recognition of bronchial fluorescence images based on visual detection. The invention relates to the technical field of visual detection, and determines multiple edge portions of the bronchus based on edge detection of the bronchial region; determines the bronchial boundary based on the recognition of these edge portions; and determines the actual morphology of the bronchus based on the bronchial boundary and the bronchial fluorescence image, ensuring the accuracy of bronchial boundary recognition and further improving the accuracy of the actual bronchial morphology. Therefore, a core review area is determined based on the actual bronchial morphology and the user's age; abnormal feature combinations are determined based on the recognition of the core review area; abnormal events are determined based on the abnormal feature combinations and the core review area; and the bronchial state level is determined based on the abnormal event, the actual bronchial morphology, and the surrounding environment of the bronchus, ensuring the accuracy of bronchial state level recognition.

The utility model relates to an infant respiratory tract foreign matter obstruction first-aid training model which comprises an infant model, a respiratory system model is arranged in the infant model, the respiratory system model comprises a trachea, the trachea is connected with a lung through a bronchus, the lung is arranged in a thoracic cavity of the infant model, and a foreign matter model is arranged in the trachea. A pressure sensor A is arranged at the position, corresponding to the back patting position, of the baby model, a pressure sensor B is arranged at the position, corresponding to the chest pressing position, of the baby model, a support and a pressure sensor C are arranged in the baby model, the pressure sensor C is located below the chest pressing position, a distance is reserved between the pressure sensor C and the chest pressing position, and the pressure sensor A, the pressure sensor B and the pressure sensor C are connected with a controller. The controller is connected with a timer and a displayer, a power source is arranged in the baby model, and the power source supplies power to the controller, the displayer, the timer, the pressure sensor A, the pressure sensor B and the pressure sensor C. The device has the advantages of being reasonable in structural design, more comprehensive in training detection, beneficial to improving the training level and the like.

The invention provides a dry and cold air exciter and an excitation method, and relates to the technical field of auxiliary breathing devices. The exciter comprises an air compression unit, a filter unit, a refrigeration and dehumidification unit and a vortex tube which are sequentially connected through air pipes, and further comprises a sensing assembly and a controller. The vortex tube separates entering compressed air into cold air flow and hot air flow through the vortex effect, and the cold air flow is used for rapidly cooling the compressed air. The air compression unit is matched with the vortex tube to achieve air cooling, high environmental protection performance is achieved, the safety of the cooled air is guaranteed, and the air cooling device is simple in structure, high in refrigeration efficiency and high in response speed. The dry cold air exciter may provide dry cold air to assist in evaluating airway reactivity by inhaling the dry cold air by a user, stimulating airway mucosa, inducing bronchial constriction.

The utility model discloses a bronchoscope's air leakage prevention negative pressure interface structure, including bronchoscope main part, the bottom of bronchoscope main part is provided with operating part, and the bottom of operating part is connected with the detection tube of checking bronchus, and the outer setting of bronchoscope main part has the connecting assembly, and the connecting assembly is provided with the suction needle cylinder of the suction of detection tube. When the bronchoscope main part cooperation detection equipment detects the bronchus of sick child, the stability of air pressure environment is very important. The device passes through the adsorption of sucking disc, and the air pressure fluctuation in subsequent suction process is effectively reduced, and the stability of air pressure environment in detection process is ensured. Meanwhile, the cooperation of positioning clamp, first spring, second connecting plate and other components realizes the firm fixing of suction needle cylinder, avoids the security risk caused by the loosening or falling of suction needle cylinder, and further improves the stability and safety of air pressure regulation.

The present invention relates to a guide sheath for peripheral bronchial lesion treatment, comprising a side tube for saline infusion, and injects physiological saline, which has been injected for peripheral bronchial dilation and access, through the side tube so that the physiological saline can efficiently reach a peripheral lung lesion as the physiological saline is injected through the side tube without insertion and removal of the guide sheath as in a conventional procedure, such that the precision and efficiency of a bronchoscopy procedure for diagnosing the peripheral lung lesion can be improved. In a conventional procedure, cold physiological saline or epinephrine for hemostasis could be administered after removal of the guide sheath and biopsy forceps, but the side tube of the guide sheath can administer a solution that assists hemostasis immediately after biopsy such that reduced side effects after the procedure and improved safety for the patient can be expected.

The present invention discloses a medical anesthesia air storage bag connection structure, comprising an anesthesia machine connector, a connecting shaft and an air storage bag; the connecting shaft passes through the air storage bag and is sealedly connected to the anesthesia machine connector; the connecting shaft rotates radially within the anesthesia machine connector; an oxygen channel and an atomization channel are respectively arranged along the axial direction of the connecting shaft; the connecting shaft is provided with an air inlet and air outlet connected to the oxygen channel and the atomization channel; the anesthesia machine connector is provided with an air inlet and air outlet corresponding to the oxygen channel and the atomization channel. During the inhalation anesthesia process, if the patient experiences airway constriction due to stimulation by anesthetics, or if the patient's existing respiratory system disease is stimulated, leading to bronchospasm, coughing, and wheezing, supportive treatment can be given without changing the original medical system environment; the complexity and unstable effect of the atomizer introduced in the atomization treatment during the inhalation anesthesia stage are simplified and overcome; and the complexity of positive pressure ventilation in medicine is simplified.

The utility model provides a bronchus occluder capable of realizing single-side and double-side switching, which solves the problems of single-side and double-side switching and the like of the bronchus occluder, and comprises a main tube body, a breathing tube is arranged in the main tube body, the breathing tube is connected with a storage tube at the end of the main tube body, and a blocking air bag is fixed on the storage tube. An inflation tube communicated with the blocking air bags is installed in the main tube body, the other end of the inflation tube is connected with near-end air bags in one-to-one correspondence with the blocking air bags, an extension tube is connected between the storage tube and the blocking air bags, the extension tube is provided with a telescopic assembly, and the extension tube and the blocking air bags can be stored in the storage tube. The utility model has the advantages of good sealing effect, flexible switching and the like.

The utility model mainly relates to a tracheal catheter for thoracic surgery, and discloses a double-bronchial ventilation catheter which comprises a tracheal catheter body and a catheter cuff arranged on the outer wall of the tracheal catheter body, the catheter cuff is connected with a catheter cuff inflation tube, and the lower end of the tracheal catheter body is divided into two bronchial catheter bodies with the same size. Each bronchial catheter is provided with a bronchial catheter outer cuff and a bronchial catheter inner cuff, the bronchial catheter inner cuff and the bronchial catheter outer cuff are connected with a bronchial catheter cuff inflation tube, and the bronchial catheter inner cuff can protrude outwards to be tightly attached to the inner wall of the bronchial catheter when the bronchial cuff is inflated, so that the bronchial catheter can be sealed. The design has the advantages of simplicity in operation, accuracy in alignment and few clinical complications.

The utility model discloses a trachea cannula which comprises a main tube body and a bronchus blocking tube connected to the end portion of the main tube body, and the end, away from the bronchus blocking tube, of the main tube body is connected with a trachea cannula connector used for being connected with equipment such as an external breathing machine. A balloon unit is sleeved on the main tube body and the bronchus blocking tube, and a camera unit, a flushing unit and an inflating unit matched with the balloon unit are arranged in the main tube body close to the trachea cannula joint; a light source unit used for illumination is arranged on the camera shooting unit, an anti-fog structure is further arranged on the camera shooting unit, the main catheter body is sleeved with a fixing unit used for fixing the mouth of a patient, and the fixing unit is movably arranged on the main catheter body. The trachea cannula is reasonable in structural design, the camera is arranged on the main catheter body, the situation that the front end of the trachea cannula damages a human body cavity due to blind insertion is avoided, the safety and the success rate of an operation are improved, the intubation time is effectively shortened, and the pain of a patient is relieved; and the light source unit and the anti-fog structure can better assist the intubation work.

The present disclosure is a telescopic endobronchial stem cell cultivation catheter that comprises a segment catheter (1), a terminal catheter (2), and a respiratory catheter (3) ensuring that ensures the prevention of the progression of COPD and provides early treatment before it progresses to advanced stages, allows the increase of the number of reduced lung parenchyma by means of its inoculation feature in advanced COPD stages, provides the removal of metaplastic cells in the bronchial walls in the application area with the rhythmic inflation-deflation movement by means of the balloons (1.2, 2.2, 3.2) and reduces the risk of future cancer formation, and increases respiratory ventilation by expanding narrowed terminal bronchioles (11) and increasing air flow to the respiratory bronchioles (12).

The present invention relates to the technical field of bronchial image analysis, and particularly relates to a bronchoscope-assisted positioning method and system for tuberculosis care. The method obtains an area correction amount based on the branch angle between the corresponding position of each frame of the internal gray-scale image of the bronchus in the virtual bronchial tree and its next bifurcation, and the area difference between the internal gray-scale image of the bronchus and the target hole area of the previous internal gray-scale image of the bronchus, and combines the distance between the corresponding position of the image in the virtual bronchial tree and its next bifurcation to correct the area of the target hole area to obtain the true area; according to the change of the true area of the target hole area of the internal gray-scale image of the bronchus between the corresponding position of the internal gray-scale image of the bronchus in the virtual bronchial tree and its previous bifurcation, it assists in positioning the bronchoscope. The present invention reduces the error in the recognition of abnormal structures in the bronchial airway and improves the accuracy of assisting in positioning the bronchoscope.

The invention discloses a traditional Chinese medicine formula with functions of relieving cough and reducing sputum as well as a preparation method and application of the traditional Chinese medicine formula. The traditional Chinese medicine formula comprises the following traditional Chinese medicine components: radix asteris, flos farfarae, rhizoma pinellinae praeparata, perilla frutescens, herba epimedii, radix rehmanniae preparata, cudweed herb, herba ardisiae japonicae, wedelia chinensis and ginseng. Through different preparation methods, the traditional Chinese medicines can be prepared into different dosage forms such as traditional Chinese medicine cigarettes, traditional Chinese medicine oral liquid, traditional Chinese medicine concentrated pills and traditional Chinese medicine tablets so as to meet the requirements of different patients. Compared with the prior art, the traditional Chinese medicine formula disclosed by the invention is prepared from natural traditional Chinese medicines, has no obvious side effect and is safe and reliable to a human body. The traditional Chinese medicine composition has obvious cough-relieving and sputum-reducing effects, especially has obvious cough-relieving and sputum-reducing effects on cough and excessive sputum caused by cold, cough and asthma, bronchitis, pneumonia, lung abscess, white lung, long-term smoking and deficiency of lung, spleen and kidney, and can be used for removing sputum, including pus sputum, old sputum and viscous sputum, accumulated in lung bronchus. The traditional Chinese medicine has effects on old and new coughs, wind cold, wind heat and rheumatic coughs.

This application relates to the field of medical simulation model manufacturing technology, specifically to a method for fabricating a fourth-level bronchus model, comprising: S1. Reverse modeling based on CT scan data of healthy human bronchi, and using Lasty-R liquid material to 3D print a lost foam of the fourth-level bronchus; S2. Applying a layered coating of platinum silicone to the surface of the lost foam and simulating the histological features of the bronchus to obtain a bronchus blank coated with a silicone layer; S3. Placing the bronchus blank in a heating environment of ≥100℃ to soften and break the internal lost foam into fragments; S4. Adding a lubricant into the cavity of the bronchus blank, removing the lost foam fragments, and obtaining a hollow fourth-level bronchus model. This method simplifies the fabrication process of the fourth-level bronchus model, shortens the cycle time, and reduces costs. The model has high simulation accuracy and strong reusability, meeting the needs of clinical training and medical teaching in multiple scenarios.