265 results about "Bronchial tubes" patented technology

The invention belongs to the technical field of medical imaging and digital twinning, and discloses a thoracic cavity whole organ system level lung four-dimensional EIT detection digital motif and a library building method, and the method comprises the following steps: S1) segmenting multiple organs such as double lungs, heart, sternum, rib and thoracic vertebra central axis skeleton, main bronchus and esophagus based on an individual CT image, and building a three-dimensional geometric model integrated with an EIT electrode array; s2) simulating breathing dynamic deformation by using a solid mechanical model; s3) establishing a coupling relationship between deformation and conductivity, and generating dynamic three-dimensional conductivity distribution; s4) solving an electromagnetic field positive problem, and generating a virtual EIT voltage database synchronous with respiration; the invention also covers pathological model integration and data enhancement strategies. According to the method, a high-fidelity, large-scale and diversified EIT virtual data set can be generated, core data support is provided for training and verifying an AI intelligent reconstruction algorithm, and a model foundation is laid for developing a lung function dynamic digital twinning system.

The invention discloses a variable-rigidity flexible conformal interventional surgical robot which comprises a flexible continuum, a driving device and a guide translation device. The flexible continuum is composed of a continuum body, a driving wire group and a variable rigidity assembly; the driving device comprises four driving motors arranged on the bracket; the guide translation device comprises a translation mechanism and a guide mechanism which are arranged on the underframe; according to the surgical robot, the flexible continuum serves as a main body, the continuum body is high in flexibility, large in bending degree, high in stability and capable of adapting to the structural characteristics that the lung bronchus is high in bending degree and complex in bending shape, and dynamic adjustment of large-bending intervention and conformal locking is achieved by being matched with the variable-rigidity assembly; the detection assembly at the front end of the flexible continuum meets operation requirements; the driving device is matched with the guide translation device, so that synchronous adjustment is realized according to an intervention path, and an intervention operation is accurately, stably and safely completed.

The invention discloses a biological nitrogen and phosphorus removal MBR sewage treatment system and a treatment process thereof. The process comprises the following steps: 1) pretreatment; 2) treatment in an anaerobic tank; (3) treating in an anoxic tank; 4) treatment in an aerobic tank; 5) MBR membrane pool treatment; sewage enters the box body through the water inlet, the moving mechanism drives the aeration mechanism and the scum cleaning mechanism to move, the aeration mechanism performs aeration treatment on the sewage in the box body, and when the aeration mechanism blows gas into the sewage through the branch gas pipe, bubbles can be scattered by spiral blades, so that the contact area between the gas and liquid is further increased, and the aeration effect is enhanced; when the sewage is subjected to aeration treatment, the scum after aeration treatment rises, the scum cleaning mechanism scrapes the scum floating after aeration for multiple times, collects the scraped scum and sends the scum out of the box body, impurities suspended in the middle layer of the sewage are fished, and the sewage after scum cleaning enters the next treatment procedure through the water outlet.

Provided in the present application are an endoscope branch positioning method and apparatus based on airway detection and tracking, and a device. The method comprises: acquiring a bronchial image at each moment, and performing airway detection on the bronchial image, so as to obtain an airway hierarchy relationship of the bronchial images; determining a first matching pursuit result on the basis of an airway feature of a bronchial image at each moment in the past and an airway feature of the bronchial image; when the airway feature of the bronchial image does not match the airway feature of the bronchial image at each moment in the past, determining a second matching pursuit result on the basis of a tracheal-tree branch map and the airway hierarchy relationship; and determining a target matching pursuit result on the basis of the first matching pursuit result and the second matching pursuit result, wherein during matching pursuit, a new detection result in each image frame matches all historical pursuit results, and automatic recovery is implemented after an error occurs.

The utility model discloses an integrated bronchus plugging catheter which comprises a tracheal catheter, a connector connected to the front end of the tracheal catheter and a bronchus catheter penetrating out of the tracheal catheter, and a partition wall extending in the length direction of the tracheal catheter is arranged in the tracheal catheter. The space in the tracheal catheter is divided into a first cavity and a fourth cavity by the partition wall, a bronchoscope or a drainage tube or a sputum suction tube is inserted into the fourth cavity, the bronchial catheter penetrates through the first cavity, a second blocking sleeve bag is fixed to the tail end, penetrating out of the first cavity, of the bronchial catheter, and a first blocking sleeve bag is fixed to the outer portion of the rear end of the tracheal catheter. Due to the fact that the bronchial catheter is limited in the first cavity, when a bronchoscope and the like are inserted into the fourth cavity, interference of the bronchial catheter is avoided; a minimum space enough to guarantee normal use of the bronchial catheter can be reserved according to the size of the bronchial catheter, so that sufficient space is reserved for insertion of a bronchoscope, a drainage tube, a sputum suction tube and the like, and smooth insertion of diagnosis and treatment equipment is guaranteed.

The invention relates to a two-stage active learning method for fine-grained bronchial airway segmentation. The method comprises the following steps: S1, generating an embedded vector of an unlabeled medical image data set based on a pre-trained self-adaptive bronchial tube segmentation model; s2, selecting a candidate sample with the maximum diversity and adding the candidate sample into a final sample set; s3, judging whether the sample number of the final sample set reaches a threshold value or not, if yes, executing S4, and if not, continuing to select the candidate sample with the maximum diversity and adding the candidate sample into the final sample set; and S4, labeling the final sample set, taking the labeled sample set as a training set of a pre-trained adaptive bronchial tube segmentation model for training to obtain an optimized adaptive bronchial tube segmentation model, and obtaining a complex bronchial network segmentation result based on the optimized adaptive bronchial tube segmentation model. Compared with the prior art, the method has the advantages of improving the value density of the selected sample set, improving the recognition precision of the fine bronchus and the like.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses a cyclophosphamide ternary nano-micelle and a preparation method thereof.The cyclophosphamide ternary nano-micelle prepared through the method can be used for treating malignant lymphoma, multiple myeloma, leukemia, breast cancer, ovarian cancer, cervical cancer, prostatic cancer, colon cancer, bronchial cancer, lung cancer and the like. Reasonable preparation steps and a preparation formula are adopted, the use of an organic reagent is reduced, the irritation of cyclophosphamide is reduced and the stability of the micelle is improved by adjusting a freeze-drying technology, and the cyclophosphamide micelle adopts amphiphilic macromolecules as a carrier material, so that the drug loading capacity and the stability of the micelle are obviously improved, and the bioavailability of the micelle is improved. The ternary nano-micelle system has the advantages that the solubility of cyclophosphamide is improved, the in-vivo bioavailability is increased, the preparation method is simple, the micelle performance is stable, and large-scale industrial production is facilitated.

Devices, systems, and methods of facilitating airway management with reduced risk of release of droplets and aerosolized pathogens from the lungs of a patient are disclosed, including a bronchoscope adapter for an endotracheal tube, an endotracheal tube with integral bronchoscope adapter, an endotracheal intubation mask system, a laryngeal mask airway-specific mask system, and a quick-seal laryngeal mask airway-specific mask system.

The utility model discloses an intrabronchial valve loader, which comprises a base, a funnel barrel part and a sleeve, the sleeve is sleeved at the front end of the base, the funnel barrel part is arranged in the middle of the base, a support funnel is arranged at the rear end of the funnel barrel part, a valve placing cavity is arranged in the center of the funnel barrel part, and a valve is arranged in the valve placing cavity. The valve containing cavity penetrates through the front portion and the rear portion of the funnel cylinder part and is communicated with the support funnel, the support funnel is used for containing a bronchial internal valve in an initial state, and the support funnel is in a funnel shape. The bronchial tube loading device has the advantages that the bronchial tube inner valve is contracted and pulled into the long and narrow placing cavity by pulling the sleeve, the front end of the catheter is fixed in the catheter placing groove, the push rod is used for pushing the bronchial tube inner valve to enter the front end of the catheter, loading can be achieved, and the whole process does not need to touch loading with hands or other tools; the operation is convenient, excessive processes are avoided, the cleanness of the valve in the bronchus is ensured, and the smooth operation is facilitated.

Apparatus and methods for deactivating bronchial nerves and ablating smooth muscle extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits ultrasound so as to heat tissues throughout a relatively large impact volume (13) to a temperature sufficient to inactivate nerve conduction and ablate smooth muscle but insufficient to cause rapid ablation or necrosis of the surrounding tissues. The treatment can be performed without locating or focusing on individual bronchial nerves or smooth muscle.

Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4 / 5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.

The invention discloses a plastic suction flushing tube used in cooperation with a visual double-lumen bronchial catheter, the plastic suction flushing tube comprises a suction flushing tube, the suction flushing tube comprises a plastic part and an operation part, the plastic part is located at the far end of the suction flushing tube, a built-in steel wire is arranged at the position 1-1.5 cm away from a hole in the far end of the suction flushing tube, and the operation part is located in the plastic part. The built-in steel wire enables the plastic part to be bent at will and to be kept shaped; the shape of the front end of the suction and flushing pipe can be flexibly adjusted, the suction and flushing pipe can be accurately guided to a target suction or flushing area, the suction and flushing accuracy is improved, the risk that sputum or secretions are not thoroughly removed is reduced, complications such as respiratory tract blockage are reduced, and the life safety of a patient is guaranteed.

The visual single-cavity bronchial cannula comprises a cannula body, a blocking balloon is arranged on the inner wall of the far end of the cannula body, a trachea cuff and a bronchial cuff which are gradually close to the far end of the cannula body are sequentially arranged on the outer wall of the cannula body, and the trachea cuff, the bronchial cuff and the blocking balloon are all connected with a cuff inflation system. The tracheal tube further comprises a camera shooting system and at least one side vent hole, the side vent hole is formed in the side wall of the tube body and located between the tracheal cuff and the bronchial cuff, and the lens end of the camera shooting system is located below the inner side of the side vent hole and shoots outwards through the side vent hole. The utility model has the advantages that the operation is simple and convenient, the intubation success rate can be improved, and the airway mucosa injury of a patient is reduced.

The invention discloses a respiratory endoscope video collecting and processing method, electronic equipment and a storage medium, and belongs to the technical field of video processing. Generating a bronchial tree diagram based on the trachea scanning image, and marking a focus generation area on the bronchial tree diagram; generating a focus navigation path based on the bronchial tree diagram and the focus generation area; acquiring a real-time endoscope video based on the focus navigation path; based on the real-time endoscope video, determining whether the endoscope reaches an airway branch fork corresponding to the focus occurrence area; if it is determined that the endoscope reaches the airway branch fork corresponding to the focus occurrence area, the video compression strategy of the real-time endoscope video is switched from the first compression strategy to the second compression strategy. According to the method, the video compression strategy can be reasonably arranged in the diagnosis and treatment process of the respiratory endoscope, the high-definition requirement of a focus area is ensured while the video transmission timeliness is ensured, and the accuracy and reliability of respiratory endoscope examination are improved.

The utility model discloses a bronchoscopy liquid pumping and sampling device which comprises an annular center frame, and a plurality of sampling mechanisms are assembled and connected to the annular center frame in a sliding mode. The sampling mechanism comprises a long spring, and the outer end of the long spring is fixedly assembled and connected with a spring seat; the spring seat is rotatably connected with a suction sampling part, the suction sampling part comprises a mounting end plate, and a plurality of suction needle tubes are assembled and connected to the mounting end plate; in the sampling process, the suction needle tube is communicated to a suction hose on the bronchoscope for sampling; through the sampling mechanism, in the detection process of the bronchoscope, washing liquid in different trachea branches is sampled separately. By means of the device, in the bronchoscope operation process, tracheal branches with different pathological changes in bronchial tissue are separated and sampled in a very efficient and convenient mode, the difficulty of operation sampling is greatly reduced, and the operation time is effectively shortened.

A catheter driving system is configured to navigate various medical catheters through complex narrow tissue openings or between organs and tissue planes, which may include lung bronchi pathway openings of 3 millimeters or less. These catheters may comprise one or more sections and optional steering cables. The catheter driving device comprises at least one rotary actuator configured to rotate at least one region of the catheter and at least one steering cable actuator configured to apply flexing force to control the direction of the catheter. To prevent the rotary actuator from tangling the steering cables, the system is further configured to rotate at least one steering cable along with the rotation of the rotated catheter region. This cable rotation may be 1:1 (e.g., synchronously) with the catheter rotation or may be configured to vary somewhat to accommodate catheter twisting, spring action, windup, and other effects.

The invention discloses a double-cavity tracheal catheter three-way control valve, which relates to the technical field of anesthesia auxiliary instruments and comprises a three-way control valve main body, a sealing ring, a rotating valve, a sealing gasket and a shell cover. The middle part of the three-way control valve main body is provided with a round pipe box, and the bottom is provided with left and right air outlet pipes, a shaft groove, two limiting strips and a main air inlet pipe on the side wall; the shaft groove is located in the bottom center of the round tube box; the centers of the left and right branch air pipe round holes and the center of the main air inlet round hole form an isosceles triangle on the same plane; the two limiting strips are positioned on two sides of the main air pipe circular hole; the rotating valve is integrally formed by a fan-shaped box cover, a right baffle, a left baffle, a rotating shaft and a T-shaped handle and is installed in a circular tube box of the three-way control valve body, and switching of single-lung and double-lung ventilation can be switched by rotating the rotating valve left and right. The anesthesia device is simple in structure, convenient to operate, high in practicability and capable of greatly relieving the workload of anesthetists.

The invention relates to the technical field of administration catheters, and discloses a neonatal intratracheal administration catheter, which comprises an administration catheter and an active agent liquid bottle placed on a suspension bracket, one end of the administration catheter is fixedly provided with an end tube extending into a bronchus, the end tube is provided with a respiration switching cylinder, and the respiration switching cylinder is internally provided with a telescopic cavity. After expiration is completed, the newborn begins to inhale, at the moment, a lifting plug body drives the lifting plug body to move towards a first baffle ring under the action of suction force and blocks a side hole again, and at the moment, a communicating hole is in an open state; therefore, the newborn can directly suck outside air through the air suction hose, at the moment, negative pressure cannot be generated in the telescopic cavity, the leakage-proof film cannot be opened, meanwhile, in the air suction process, a liquid active agent originally located in the lifting plug body can be sucked into the lung along with the air, and the effect that the active agent is sprayed to the lung is achieved.

A phosphodiesterase type 5 inhibitor is used in the preparation of a medicament for resisting fibrotic diseases. Experiments in animal models of ischemia-reperfusion (UIRI)-induced renal fibrosis, unilateral ureteral obstruction (UUO)-caused kidney fibrosis and idiopathic pulmonary fibrosis show that a PDE5 inhibitor such as tadalafil, sildenafil and vardenafil can significantly inhibit the expression of multiple fibrosis iconic proteins such as fibronectin, collagen I, renal injury molecule-1, and α-skeletal muscle actin in UIRI and UUO renal fibrosis lesions, improves glomerulopathy, degree of renal tubular distension, renal interstitial collagen fiber deposition and inflammatory cell infiltration, reduces the fibrotic area within the lesion, and significantly inhibits the progression of renal fibrosis; and the PDE5 inhibitor can significantly improve smooth muscle proliferation and inflammatory cell infiltration in bronchioles and pulmonary arterioles of idiopathic pulmonary fibrosis lesion, improve damage condition of alveolar tissue, and significantly inhibit the progression of pulmonary fibrosis.

A catheter driving system is configured to navigate various medical catheters through complex narrow tissue openings or between organs and tissue planes, which may include lung bronchi pathway openings of 3 millimeters or less. These catheters may comprise one or more sections and optional steering cables. The catheter driving device comprises at least one rotary actuator configured to rotate at least one region of the catheter and at least one steering cable actuator configured to apply flexing force to control the direction of the catheter. To prevent the rotary actuator from tangling the steering cables, the system is further configured to rotate at least one steering cable along with the rotation of the rotated catheter region. This cable rotation may be 1:1 (e.g., synchronously) with the catheter rotation or may be configured to vary somewhat to accommodate catheter twisting, spring action, windup, and other effects.

The utility model relates to the technical field of medical instruments, in particular to a steering tracheal catheter which comprises a main catheter body, the head end of the main catheter body is connected with a standard connector, the standard connector is used for being connected with a breathing machine, an air bag I is arranged on the outer wall of the tail of the main catheter body and connected with an inflation adjusting mechanism I, and the inflation adjusting mechanism I is used for adjusting the inflation adjusting mechanism. A steering tube section is arranged at the head part of the main catheter, and after the main catheter is placed into a trachea and / or a bronchus of a human body, the steering tube section is positioned outside the mouth or the nose of the human body, so that the steering tube section can steer at will outside the mouth or the nose of the human body. According to the utility model, the steering tube section is arranged at the head part of the main catheter, and after the main catheter is placed into the trachea and / or the bronchus of the human body, the steering tube section is positioned outside the mouth or the nose of the human body and can steer at will outside the mouth or the nose of the human body; the part, located outside the mouth or the nose of the human body, of the tracheal catheter is prevented from being bent.

The invention discloses an anti-reflux spray type trachea cannula integrated with a power device and an airway surface anesthesia method.The anti-reflux spray type trachea cannula comprises a trachea cannula device, a spray power device and a medicine bottle, the trachea cannula device comprises a trachea cannula body and a spray assembly, and the spray assembly comprises a spray head, a spray connecting pipe and a spray connector; the spray head is arranged in the trachea cannula body and located at the end inserted into the human body, one end of the spray connecting pipe is connected with the spray connector, and the other end is connected with the spray head. The suction end of the spray power device is connected with the medicine bottle, and the discharge end is connected with the spray joint; when the trachea cannula is inserted into and pulled out of a patient, anesthetic liquid medicine in the medicine bottle is conveyed to the spraying head through the spraying power device to be sprayed out for surface anesthesia, so that the occurrence of violent stress reaction during cannula insertion and cannula pulling can be effectively reduced; the occurrence rate of complications such as bucking, laryngeal spasm, tracheal spasm, bronchus spasm, blood pressure drastic increase and arrhythmia is remarkably reduced, and the safety and comfort of a patient are effectively improved.

The utility model discloses a kind of reusable bronchial endoscope handle, including first shell, second shell and rotating mechanism, first shell and second shell are connected with lid and constitute handle cavity, and the pipe end of handle cavity is provided with insertion tube;Rotating mechanism has rotating wheel and axial pull switch being set on rotating wheel, rotating wheel is set in handle cavity, axial pull switch is set to the outside of first shell and / or second shell, rotating wheel is axially rotated and is connected by traction line and drives insertion tube swing.Equipped with axial pull switch on the outer surface of shell and fixedly connected with the output shaft of rotating wheel in this way, and then drive rotating wheel to axially rotate and drive insertion tube swing, can be exempted from to open shell hole in the side of two shells, and then improve the overall waterproof effect of bronchial endoscope handle, improve service life, and cleaning is more convenient, bronchial endoscope handle can be reused multiple times, save resources, reduce medical cost.

The present application belongs to the technical field of medical instruments, and discloses a visual silicone double-lumen endobronchial tube, comprising: a main trachea, one side of the main trachea is connected to a ventilator plug, and the other side is connected to a bronchus through a main tracheal cuff, and a bronchial cuff is arranged on the bronchus; a first inflation hole is arranged on the side where the main tracheal cuff is connected to the main trachea, a second inflation hole is arranged on the side of the bronchial cuff close to the main tracheal cuff, and an inflation structure is arranged at the first inflation hole and the second inflation hole, and the inflation structure comprises an inflation joint, an inflation tube and a gas storage cavity, and the inflation joint is connected to the gas storage cavity through the inflation tube, and the gas storage cavity is sealed and clamped with the first inflation hole or the second inflation hole; an air outlet is arranged at the gas storage cavity toward the inflation hole, and an inflation locking structure is arranged at the air outlet, and the inflation locking structure cooperates with the inflation hole to inflate and lock the main tracheal cuff or the bronchial cuff. The present application can improve the safety of endobronchial tube use.

The invention discloses a tracheostomy tube for assisting cough of a patient, and relates to the technical field of medical instruments, the tracheostomy tube comprises a catheter, one end of the catheter inserted into the tracheostomy tube is provided with an inflatable and deflatable air bag, and one end of the catheter located outside the tracheostomy tube is provided with a foldable baffle. And a one-way valve capable of feeding air into the guide pipe is arranged on the guide pipe at the end. According to the device, a patient can be assisted in cough action, a low-resistance release path is provided for high-pressure and high-speed airflow generated in the suffocation stage before cough, the effect that the glottis is suddenly opened due to pressure during natural cough is simulated, and therefore secretions in the trachea and the bronchus are more effectively removed.

The invention is a method for stimulating tracheobronchial air of a patient suffering from an obstructive ventilatory disorder and modifying a rheology of the patient's tracheobronchial mucus. The method includes: interfacing a respiratory system of the patient with a physiological interface connected to a negative pressure generator with a connecting pipe; applying alternations of negative pressure with the negative pressure generator and venting impulses with a first determined frequency and duty cycle during a first part of an expiration cycle; applying a succession of alternations of negative pressure with the negative pressure generator and venting impulses with a second determined frequency and a second determined duty cycle during a second part of said expiration cycle; a duty cycle corresponding to a ratio between the duration during which a negative pressure is applied and the total duration of an expiration cycle; and reiterating a defined number of expiration cycles.

The present application provides a bronchial extraction method, device and computer equipment based on CT images, which relates to the field of CT image processing technology. The method includes: obtaining a lung electronic computer tomography CT image to be segmented; segmenting the CT image to obtain a pulmonary interstitial mask image, a bronchial mask image and a pulmonary artery mask image; segmenting the bronchial mask image to obtain at least three bronchial segment mask images, segmenting the pulmonary artery mask image to obtain at least three pulmonary artery segment masks, determining the classification result of the bronchial mask image based on the adjacent and docking relationship of each bronchial segment, and determining the classification result of the pulmonary artery mask image based on the adjacent and docking relationship of the pulmonary artery; fusing the classification result of the bronchial mask image and the classification result of the pulmonary artery mask image, and generating the final bronchial mask image based on the accompanying relationship of the pulmonary artery corresponding to the bronchi.

An automatic control system for a tracheobronchial pneumatic stimulator (10) intended to be connected to a subject, the stimulator (10) comprising: a pressure unit (13) configured to generate a set of negative pressure pulses during a relaxation exhalation of the subject, each pulse corresponding to an output of the pressure unit (13); and a connection assembly (11, 12) configured to connect the pressure unit (13) to the subject's respiratory system. The control system comprises: a pressure sensor (15) configured to measure an internal negative pressure (P) applied to the subject's respiratory system corresponding to each pulse after it is generated by the pressure unit (13); a calculation module (32) configured to compare in real time the absolute value of the measured internal negative pressure (P) with a predetermined threshold (S) and, based on the comparison result, determine an updated output value to be applied to the pressure unit (13) such that the absolute value of the subsequent internal negative pressure (P) corresponding to the updated output value is less than the absolute value of the threshold (S); and a control module (33) configured to apply the updated output value to the pressure unit (13) before the generation of the next pulse.

This invention discloses a method and system for boundary recognition of bronchial fluorescence images based on visual detection. The invention relates to the technical field of visual detection, and determines multiple edge portions of the bronchus based on edge detection of the bronchial region; determines the bronchial boundary based on the recognition of these edge portions; and determines the actual morphology of the bronchus based on the bronchial boundary and the bronchial fluorescence image, ensuring the accuracy of bronchial boundary recognition and further improving the accuracy of the actual bronchial morphology. Therefore, a core review area is determined based on the actual bronchial morphology and the user's age; abnormal feature combinations are determined based on the recognition of the core review area; abnormal events are determined based on the abnormal feature combinations and the core review area; and the bronchial state level is determined based on the abnormal event, the actual bronchial morphology, and the surrounding environment of the bronchus, ensuring the accuracy of bronchial state level recognition.