12434results about "Vaccination/ovulation diagnostics" patented technology

The sperm collection device includes a core member having an insertion hole for a penis and an insertion space, and a container having an internal space in which the core member is accommodated. The container includes a cylindrical base unit having a base end open in an axial direction of the base unit and attached to an insertion-hole-side end of the core member, and a cylindrical movable unit having a base end open in an axial direction of the movable unit and a front end being closed, and attached rotatably around an axis of the movable unit with respect to the other end of the base unit. In an overlapping part in which the base end of the movable unit overlaps the other end of the base unit, an airflow path and an adjustment mechanism are provided.

An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.

A bodily-fluid transfer device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing having a fluid reservoir at a first end, a fluid outlet at a second end, and a longitudinally extending fluid impermeable layer coupled to the fluid reservoir and the fluid outlet and defining a longitudinally elongated opening between the reservoir and the outlet. The assembly can further include a fluid permeable support disposed within the casing with a portion extending across the elongated opening, and a fluid permeable membrane disposed on the support and covering at least the portion of the support that extends across the elongated opening, so that the membrane is supported on the support and disposed across the elongated opening. The assembly can further include a tube having a first end disposed in the reservoir and a second, fluid discharge end.

The invention relates to the technical field of medical instrument control, in particular to a lung biopsy sampling needle stabilizing method and system based on dynamic respiration compensation. The stabilizing method comprises the following steps: acquiring a respiratory movement signal of a patient in real time through a multi-source biosensor, wherein the multi-source biosensor comprises an optical fiber strain sensor array, a diaphragm myoelectricity sensor and a respiratory airflow sensor which are deployed at the chest and abdomen. According to the method, millimeter-microsecond-level accurate and stable control over the lung biopsy sampling process is achieved by establishing a cooperation mechanism of a breathing phase-displacement nonlinear mapping model and a macro-micro composite driving framework. The biological rationality of displacement prediction is improved through deep coupling of multi-mode breathing signals, and the chest wall non-uniform deformation gradient is analyzed in space based on cross topology deployment of an optical fiber strain sensor in an intercostal space area in combination with cross-scale feature fusion of myoelectricity and airflow sensing.

An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.

An apparatus includes a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing defines an inner volume and has an inlet port that can be fluidically coupled to a patient and an outlet port. The fluid reservoir is disposed in the inner volume to receive and isolate a first volume of a bodily-fluid. The flow control mechanism is rotatable in the housing from a first configuration, in which a first lumen places the inlet port is in fluid communication with the fluid reservoir, and a second configuration, in which a second lumen places the inlet port in fluid communication with the outlet port. The actuator is configured to create a negative pressure in the fluid reservoir and is configured to rotate the flow control mechanism from the first configuration to the second configuration after the first volume of bodily-fluid is received in the fluid reservoir.

A system having a processor and memory coupled to the processor is provided. The memory stores a central testing database having a plurality of test configuration profiles and a central patient database. A first communications interface coupled to the processor receives a request from a test device for at least one of the plurality of test configuration profiles and sends the requested test configuration profile to the test device. The first communications interface also receives a test result collection instance from the test device. The processor is configured to store the test result collection instance in the central patient database.

A system having a processor and memory coupled to the processor is provided. The memory stores a local testing database having a test configuration profile with the test configuration profile having an intensity threshold value denoting a positive test result. The system includes a carrier for receiving a cassette containing a lateral flow assay (“LFA”) strip and an LFA strip reader coupled to the processor for reading the LFA strip regardless of alignment of the cassette within the carrier and for transmitting an LFA strip image to the processor. The processor determines an LFA test result based on comparing an intensity value of a portion of the LFA strip image to the intensity threshold value and provides the LFA test result on an indication panel.

The invention discloses an endoscope with a built-in grabbing mechanism, and relates to the technical field of medical instruments. According to the technical scheme, the device comprises a clamp assembly, a driving outer pipe and a driving inner wire; the grabbing mechanism further comprises a grabbing mechanism shell, a first moving seat and a second moving seat, wherein the first moving seat and the second moving seat are arranged in the grabbing mechanism shell. The near end of the driving outer tube is connected with the first moving seat, and the near end of the driving inner wire is connected with the second moving seat; when the second moving seat is fixed relative to the grabbing mechanism shell, the first moving seat moves towards the far end direction relative to the grabbing mechanism shell so as to control the clamp assembly to execute the clamping action. According to the invention, the clamping action is carried out while forward extension is carried out, so that high-precision operation is facilitated, and tissues can be accurately clamped; and moreover, the grabbing mechanism is integrated in the endoscope handle, so that accurate single-hand control is facilitated, meanwhile, the clamping action is controlled in a button mode, the human engineering is met, and operation is convenient.

A drainage system including a catheter including a sensor, a first valve in fluid communication with an interior of the catheter, a controller communicatively coupled to the sensor, the controller including logic configured to direct opening and closing of the first valve using one or both of an elapsed time and a presence of a predetermined condition, and a venturi pump in fluid communication with the interior of the catheter.

The invention provides a chameleon-imitated self-growing throat swab sampling robot, which comprises a robot body, which is formed by self-growing a flexible material in a pneumatic mode, an internal channel communicated with the atmosphere is formed in the robot body, and the throat swab is grabbed and released according to the change of the grabbing length of the throat swab by the internal channel; the driving storage mechanism is connected with the front end of the robot body and is used for storing the flexible material required by the growth of the robot body and providing power for the growth and recovery of the robot body; the pneumatic artificial muscle is located on the surface of the robot body and used for controlling the pose of the tail end of the robot. The tail end executing mechanism is located at the tail end of the robot body and comprises a recycling structure and a data collecting module, and the recycling structure guides the flexible material in a rolling friction mode so as to assist recycling of the robot body. According to the method, the predation process of aiming, launching, swallowing and withdrawing of a chameleon is imitated, the flexibility and conveying characteristics of the self-growing robot are fully utilized, and rapid and safe collection of the throat swab is achieved.

The present invention relates to organic thin film sensors and the preparation and use thereof in sensing applications, and in particular in glucose sensing. The sensor is characterised by a layered structure comprising a porous wicking layer whose surface is configured to receive a liquid sample. An enzyme is disposed on or within the porous layer for facilitating the generation of a charge carrier from an analyte. A polymer layer in contact with the porous layer is connected to an ohmic conductor for applying a gate voltage to the polymer layer, the polymer layer being conductive to the charge carrier; and an organic semiconducting layer is connected to a source electrode and a drain electrode.

A handheld endoscope has a disposable, single-use portion that includes a distal tip, cannula, housings, and a proximal port that is connected to a substantially straight working channel. The cannula is rotatable about the main longitudinal axis of the cannula. The endoscope also includes a re-usable portion that has a handle and display module. The single-use and re-usable portions mate and un-mate with each other via physical side-mounting arrangement as well as separate electrical connectors. The handle can house imaging system electronics that support manual and auto imaging modes which can be selected via touch screen control on the display module. The re-useable portion is sealed with various o-rings and / or gaskets and can be highly fluid resistant to facilitate disinfecting and / or sterilization.

A fluid control device includes an inlet configured to be placed directly or indirectly in fluid communication with a bodily fluid source and an outlet configured to be placed in fluid communication with a fluid collection device. The fluid control device has a first state in which a negative pressure differential produced from an external source such as the fluid collection device is applied to the fluid control device to draw an initial volume of bodily fluid from the bodily fluid source, through the inlet, and into a sequestration portion of the fluid control device. The fluid control device has a second state in which (1) the sequestration portion sequesters the initial volume, and (2) the negative pressure differential draws a subsequent volume of bodily fluid, being substantially free of contaminants, from the bodily fluid source, through the fluid control device, and into the fluid collection device.

The invention relates to a sweat real-time detection device and a preparation method thereof, the sweat real-time detection device sequentially comprises a collection layer and a detection layer from bottom to top, the collection layer comprises a fitting area, a fan-shaped flow guide area and a collection area, the fitting area is used for fitting skin, and the flow guide area is used for guiding sweat into the collection area; a plurality of guide vanes facing the collecting area are arranged in the guide area, and the guide vanes are triangular; the collecting area is connected into the fan-shaped included angle of the flow guide area and penetrates through the collecting layer; the detection layer is internally provided with a drainage area, a detection area and a micro-channel, the drainage area corresponds to the collection area and is used for draining sweat in the collection area to the detection area, and the detection area is provided with a sweat detection chip; the micro-channel is emitted from the drainage area, penetrates through the detection area and extends to the outermost side of the detection layer. The sweat collection device has the characteristics of high sweat collection efficiency, sufficient sweat collection amount, timely sweat detection after collection, rapid sweat analysis and detection process, reliable detection result and the like.

The invention concerns a urine analysis device comprising a case configured to be positioned entirely within a toilet bowl. The case comprises a front face for receiving a stream of urine directly from a user urinating in the toilet bowl and a rear face opposite the front face. The device comprises a collection aperture located on the rear face, the collection aperture being configured to collect liquid inside the case. The device comprises at least a spacer protruding out of the rear face and configured to be in contact with the toilet bowl.

A urine analysis device includes a case configured to be positioned entirely within a toilet bowl. The case includes a front face for receiving a stream of urine directly from a user urinating in the toilet bowl and a rear face opposite the front face. The device includes a collection aperture located on the rear face, the collection aperture being configured to collect liquid inside the case. The device includes at least a spacer protruding out of the rear face and configured to be in contact with the toilet bowl.

Provided in the present invention is a sperm extractor with a telescopic function, including: a motor for providing power; a crank mounted on the motor; a connecting rod connected to the crank and an inner container; and the inner container for sperm extraction, where the motor rotates to drive the crank to rotate, and the crank drives the connecting rod to push or pull the inner container for sperm extraction. According to the present invention, the motor rotates to drive the crank to rotate, and the crank drives the connecting rod to push or pull the inner container to make a telescopic motion for sperm extraction; a Hall switch is further disposed on a printed circuit board (PCB) to sense positions of the crank and the connecting rod to control a stop position of the motor, so as to achieve reset.

The invention discloses a blood, urine and body fluid collecting, detecting, analyzing and uploading system based on multi-sensor integration, which comprises the following modules: a blood collecting module for collecting a blood sample; the urine collection module is used for detecting urine; the body fluid collecting module is used for detecting body fluid; the data processing module is used for preprocessing data; the feature extraction and classification module is used for constructing a multi-modal feature matrix based on a neural structure search network, a support vector machine and a random forest algorithm; the anomaly detection module is used for generating a weighted anomaly score in combination with an isolated forest and a depth anomaly detection model; the time sequence analysis module is used for analyzing the health trend by using a variational auto-encoder-generative adversarial network; the health portrait and risk assessment module is used for constructing a health map by adopting a graph convolutional network; and the encryption and uploading management module is used for encrypting by using AES and RSA and managing the data access authority based on the intelligent contract. According to the invention, a multi-modal sensor and an intelligent algorithm are integrated, and collection, detection, analysis, encryption and uploading of blood, urine and body fluid are realized.

Systems, methods, and devices feature a wearable device that includes a set of needles sized for access to interstitial fluid. The wearable device also includes a chemical indicator associated with each needle. A concentration of an analyte within the interstitial fluid can be determined based on one or more optical properties of the chemical indicator.

A cervical inspection device (610) for performing a cervical smear test is provided. The device (610) has a tubular body (612) having a first end (614) which is engagable by an operator and a second end (616) which is insertable into a patient's vaginal canal, the tubular body (612) having a central bore (620) which extends along its longitudinal axis for receiving a cervical sampling brush (622) therethrough. There is also an expansion element (630) at or adjacent to the second end (616) of the tubular body (612) and control means operable from the first end (614) of the tubular body (612) for selectably expanding and / or contracting the expansion element (630). The expansion element (630) forms a protective region beyond the central bore (620) in an expanded condition thereof for the said cervical sampling brush (622) to move through during a cervical smear test.

Systems, devices, and methods for planning an endoscopic tissue acquisition procedure for acquiring tissue from an anatomical target are disclosed. An endoscopic system comprises a steerable elongate instrument and a processor. The steerable elongate instrument can be positioned and navigated in a patient anatomy and acquire tissue from an anatomical target via a biopsy tool associated with the steerable elongate instrument. The processor can receive an image of the anatomical target, apply the received image to a trained machine-learning (ML) model to determine a tissue acquisition plan that includes a recommended biopsy tool and operational parameters for navigating the steerable elongate instrument or maneuvering the recommended biopsy tool. The tissue acquisition plan can be presented to a user, or used to facilitate a robot-assisted tissue acquisition procedure.

The invention concerns a method of monitoring (800) at least one biomarker with a measurement plan comprising a datum related to a predetermined biomarker (710) to analyze and at least one temporal analyzing window to analyze the predetermined biomarker (710). At least one of collecting (918) a urine sample and analyzing (919) the urine sample is performed at least in response to determining that an internal time value is within the at least one temporal analyzing window of the measurement plan.

Described are systems and methods for training a machine-learning model to generate image of biological samples, and systems and methods for generating enhanced images of biological samples. The method for training a machine-learning model to generate images of biological samples may include obtaining a plurality of training images comprising a training image of a first type, and a training image of a second type. The method may also include generating, based on the training image of the first type, a plurality of wavelet coefficients using the machine-learning model; generating, based on the plurality of wavelet coefficients, a synthetic image of the second type; comparing the synthetic image of the second type with the training image of the second type; and updating the machine-learning model based on the comparison.

A system for, display controller connected to, and a method of, operating a robotic catheter system which is configured to manipulate a catheter having one or more bending segments along the catheter's length and a catheter tip at the distal end thereof, and which includes an actuator unit coupled to the bending segments via one or more drive wires arranged along a wall of the catheter. The method comprising: inserting at least part of the catheter into a lumen along an insertion trajectory that spans from an insertion point to a target; causing the actuator unit to actuate at least one of the one or more drive wires to align the catheter tip with the target; determining the position and / or orientation of the catheter tip with respect to the target; and displaying information about an accuracy of alignment between the catheter tip with respect to the target.

An automated urinary output (“UO”)-measuring system includes a fluid container including a console coupled to one or more ultrasonic sensors and one or more accelerometers. The console includes a processor configured to receive accelerometer values from the one or more accelerometers, to determine an acceleration state of the fluid container, to activate the one or more ultrasonic sensors when the acceleration state of the fluid container is below a threshold, and to measure a volume of fluid in the fluid container when the acceleration state of the fluid container is zero. The system can further include a removable valve coupled to the fluid container and an attachment device including a pocket configured to accommodate the fluid container.

The invention discloses an auxiliary renal puncture device for the nephrology department, and belongs to the technical field of renal puncture, the auxiliary renal puncture device comprises a sickbed, a plurality of supporting legs are fixedly arranged at the bottom of the sickbed, fixing plates are fixedly arranged on the two sides of the sickbed, and second sliding blocks are slidably connected to one sides of the two fixing plates; the breathing frequency and amplitude of a patient are captured in real time through an infrared breathing monitoring module, and displacement data generated by breathing of the kidney are accurately obtained in combination with motion sensing modules such as a lead screw encoder and a driving gear angle encoder. The intelligent control system drives the first stepping motor and the second stepping motor to adjust the position of the portal frame based on six-dimensional force sensor data of the force sensing module, meanwhile, the angle of the puncture needle is adjusted in real time through feedback of a mechanical arm joint encoder, and dynamic compensation of kidney respiratory movement is achieved. According to the mechanism, the puncture deviation caused by breathing can be controlled within the range of + / -0.5 mm, the puncture positioning precision is remarkably improved, and poor sample quality or operation risks caused by breathing movement are avoided.

The inventions provided herein relate to injection applicators, tissue markers and uses thereof, e.g., to mark a target tissue site (e.g., a biopsy site in a breast tissue) or to produce a cell scaffold. The tissue markers described herein are designed to be resistant to fast migration (e.g., immediate migration after implantation through a needle track) and slow migration (e.g., over an extended period of time) upon implantation at a target tissue site (e.g., a biopsy site in a breast tissue), without using an adhesive. Additionally or alternatively, the tissue markers described herein can be readily detectable by at least one imaging modality, e.g., but not limited to magnetic resonance imaging, X-ray imaging, ultrasound imaging, or a combination thereof.