1252results about "Radiation therapy" patented technology

Hydrogen-bonded framework nanoparticles comprising a chemiluminescent compound (e.g., L-012) are provided and can be used, e.g., for sono-optogenetic treatment of neurodegenerative diseases such as Parkinson's disease. Related in vivo and therapeutic methods are also provided.

Devices and methods are disclosed for treating tissue with microwave energy. Such devices and methods are able to treat cavities or surface tissue by creating one or more area or volumetric lesions. Also disclosed are flexible, low-profile devices that can be inserted non-invasively or minimally invasively near or into the target tissue as well as microwave antennas designed to generate ablation profiles that can ablate a large area or a large volume of target tissue in a single ablation. The devices include antennas wherein the field profile generated by an antenna is tailored and optimized for a particular clinical application. The antennas use unique properties of microwaves such as interaction of a microwave field with a metallic object and the use of additional shaping elements to shape the microwave field.

One ECR ion source generates a He < 2 + > ion beam, the other ECR ion source generates a H2 < + > ion beam, the He < 2 + > or H2 < + > ion beam is selected by a deflection magnet and then transmitted and focused by LEBT to enter an RFQ, the focusing factor of the RFQ is increased and then reduced, DTL is IH-DTL designed by adopting KONUS beam dynamics and comprises two KONUS periods, the working frequencies of the RFQ and the DTL are respectively 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, after He < 2 + > or H2 < + > ion beams are accelerated by RFQ and DTL, the MEBT distributes and transmits the ion beams to a downstream accelerator and an isotope production device. According to the proton helium ion implanter provided by the invention, the particle beam can meet the injection requirement of a subsequent synchrotron, the miniaturization of the proton helium ion implanter is realized, and the production of medical isotopes is considered.

The invention discloses a hidden multi-mode brain state real-time monitoring and closed-loop intervention system, and relates to the technical field of intelligent wearable equipment. The system comprises a cap body, and further comprises a multi-point electrode array used for collecting EEG (electroencephalogram) signals, EOG (eye movement) signals and EMG (electromyography) signals of a human body; the brain blood oxygen monitoring module is used for monitoring brain blood oxygen saturation; the signal receiving and processing module is used for preprocessing and analyzing data acquired by the multi-point electrode array and the brain blood oxygen monitoring module; the multi-mode stimulation module is used for implementing sensory and nerve stimulation on the user according to a judgment result of the state judgment module so as to intervene in a drowsiness or attention decline state; and the power supply module and the communication unit are used for providing a working power supply for the modules needing power supply in the system and carrying out data communication with external terminal equipment. The system can monitor the waking degree of the user with high precision and carry out closed-loop feedback intervention by various stimulation means.

The utility model belongs to the field of medical instruments, and particularly relates to an integrated radioactive particle protection implanter, which comprises a particle bin for storing a particle short rod, a particle bin seat with a handle, a push needle and a puncture needle, the particle bin seat is connected with the puncture needle through a connecting end, and the particle bin seat comprises an upper bin seat and a lower bin seat. A containing cavity used for containing the particle bin is formed between the upper bin base and the lower bin base, the upper bin base is connected with the handle, the handle, the upper bin base, the particle bin and the lower bin base are sequentially and coaxially provided with material pushing holes allowing the pushing needle to penetrate through, and the discharging ends of the material pushing holes are located on the lower bin base and connected with the connecting end. And the particle bin and the particle bin seat are integrated, so that medical staff are prevented from being affected by radiation in the installation process, and the situation that disputes are generated between hospitals and supply manufacturers due to the fact that the particle short rods are lost is reduced.

An automated clinical decision support method for treatment re-planning that enhances a CBCT scan using information from an initial CT scan of the patient to create a synthetic CT scan; adapts contours of organ(s) and tumour(s) from the initial CT scan to align with the synthetic CT scan; and calculates a delivered radiation dose from the synthetic CT scan; compares these against an original treatment plan to detect deviations exceeding preset thresholds, and triggers alerts with assigned priority levels for a re-plan decision.

Embodiments of systems, devices, and methods relate to initiating beam transport for an accelerator system. An example method includes increasing a bias voltage of one or more electrodes of the accelerator system to a first voltage level and extracting a charged particle beam from a beam source such that the beam is transported through the accelerator system. The beam has a beam current at a first beam current level that results in a first transient voltage drop of the accelerator system within a threshold. The method further includes increasing the beam current at a rate that results in one or more subsequent transient voltage drops of the accelerator system until the accelerator system has reached nominal conditions. The one or more subsequent transient voltage drops are within the threshold. Another example method includes biasing one or more electrodes of an accelerator system to a voltage level and selectively extracting, according to a duty cycle function, a charged particle beam from a beam source such that the charged particle beam is transported through the accelerator system. The duty cycle function can be linear or non-linear and can include a frequency f. The duty cycle function can include a variable pulse duration such that the variable pulse duration increases over time with each selective extraction of the charged particle beam.

Disclosed in the present invention are a scanning box device and an electron accelerator, the electron accelerator comprising an accelerating tube and a deflection coil; the scanning box device comprising a scanning chamber and a scanning box, wherein the scanning chamber is sealingly connected to the scanning box; the scanning chamber is arranged above the scanning box; the accelerating tube is arranged above the scanning chamber; the deflection coil is arranged on the outer side of the scanning chamber; and the scanning chamber is made of a non-metallic material. The present invention can prevent the generation of eddy currents in the scanning box, thus reducing the problems of energy loss and heat generation, improving the performance and stability of the apparatus.

The invention discloses a robot assisted diagnosis and treatment system for a nuclear medicine ward and an application method. The robot assisted diagnosis and treatment system comprises an AI robot for non-contact assisted diagnosis and treatment; the robot library is arranged on the same layer of the nuclear medicine ward; the remote interaction platform is used for issuing related instructions and man-machine interaction to the AI robot; a radiation protection and monitoring module, an identity recognition module, a health propaganda and education module, a ferry module, a visual doctor-patient communication module, a communication module, an RFID access control module and an environment disinfection module are integrated on the AI robot; the AI robot is connected with an external subcutaneous injection module, an external intravenous injection module, an external medicine distribution module and an external living goods conveying module through corresponding switching assemblies. According to the robot-assisted diagnosis and treatment system for the nuclear medicine ward and the application method, a semi-autonomous and remote interaction mode is used for replacing medical staff to execute face-to-face diagnosis and treatment behaviors with patients, and non-contact diagnosis and treatment are achieved through human-machine-patient high cooperation in the whole diagnosis and treatment process.

A device 100 for developing the concentration, the device 100 comprising: an optical sensor unit, the optical sensor unit comprising a plurality of one or more lenses 201, 202 capable of holding sensitive elements, the plurality of sensitive elements being configured to detect a user-provided biological signal in at least three operating modes; three switches for switching between the plurality of operating modes; a plurality of illumination units configured to indicate each of the plurality of operating modes by emitting a predetermined light signal; a processing unit for processing information using artificial intelligence.

A neurostimulation system may include an implantable neurostimulator. An implantable neurostimulator may include a first sensor configured to sense internal data relating to a symptom of a neurological movement disorder of a patient. An implantable neurostimulator may include an internal stimulator configured to provide an internal stimulation output to an internal target area of a patient. An implantable neurostimulator may include a first wireless communication device configured to communicate internal data with a network. A neurostimulation system may include a wearable neurostimulator. A wearable neurostimulator may include a second sensor configured to sense external data of a patient. A wearable neurostimulator may include an external stimulator configured to provide an external stimulation output to an external target area of a patient. A wearable neurostimulator may include a second wireless communication device configured to communicate external data with a network and receive internal data from the network.

Disclosed herein is a waveguide cell having a helical cavity. The waveguide cell has a central axis and a cavity having a transverse cross section whose rotational position about the central axis varies along the central axis. There is also disclosed a method a determining the shape of a waveguide cell.

A method of treating non-melanoma skin cancer in a patient in need thereof is provided. The method includes administering a hedgehog pathway inhibitor to the patient and applying to a region of skin on the patient, a topical composition comprising 5-aminolevulinic acid, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient. The method further includes incubating the topical composition on the region of skin; and illuminating the region of skin with a light source at an irradiance density of 20 mW / cm2.

Disclosed herein is a method for generating one or more synthetic electron density, sED, images. The method comprises obtaining a first image of a first imaging modality, the first image depicting an anatomical region of a subject. The method also comprises generating, using a trained machine learning model and the first image, a sED image depicting the anatomical region, wherein the trained machine learning model has been trained using a set of training images comprising a first subset of training images of the first imaging modality, and a second subset of training images in which each training image comprises electron density, ED, information.

The invention relates to a method of MR imaging of a body (10) of a patient positioned in an examination volume of an MR device (1). It is an object of the invention to provide a method that enables geometrically correct MR-only radiation therapy planning at minimum scan times. The method of the invention comprises the following steps: acquiring first MR imaging data representative of at least one region of the body (10); analyzing said first MR imaging data to delineate at least one anatomical structure within said body region; acquiring second MR imaging data of said body region using a multi-point Dixon sequence; deriving a B0 map from said second MR imaging data; analyzing said B0 map to determine at least one low fidelity region of said B0 map; performing B0 mapping to refine the B0 map using a multi-acquisition gradient echo sequence restricted to at least one region where said delineated anatomical structure and said low fidelity region overlap completely or partially; and correcting geometrical distortions in said first and / or second MR imaging data using the refined B0 map. Moreover, the invention relates to a MR device (1) for carrying out the method, and to a computer program to be executed on a MR device (1).

The invention provides a compact synchrotron vacuum system and a design method, and relates to the technical field of particle acceleration. The vacuum system comprises a first vacuum unit and a second vacuum unit, the first vacuum unit comprises at least two first beam deflection vacuum tubes, and the adjacent first beam deflection vacuum tubes are connected through a first beam regulation and control vacuum tube; the second vacuum unit comprises at least two second beam deflection vacuum tubes, and the adjacent second beam deflection vacuum tubes are connected through a second beam regulation and control vacuum tube; a second beam deflection vacuum tube at one end of the second vacuum unit is connected with a first beam regulation vacuum tube at the first end of the first vacuum unit, and a second beam deflection vacuum tube at the other end of the second vacuum unit is connected with a first beam regulation vacuum tube at the second end of the first vacuum unit; and a beam diagnosis element is arranged in the first beam regulation and control vacuum tube of the first vacuum unit, so that the perimeter of the vacuum system can be shortened, and the popularization difficulty of the medical accelerator treatment device in small and medium-sized medical institutions is reduced.

A vagus nerve stimulation system for stimulating a vagus nerve in a biological subject, the system including a clip configured to be attached to a tragus of the subject, the clip including opposing arms configured so that a distal end of the arms are biased towards each other and electrodes positioned proximate a distal end of the arms on opposing faces so that the electrodes are urged into engagement with opposing faces of the tragus and a signal generator electrically connected to the electrodes, the signal generator being configured to generate at least one therapy signal that is applied to the vagus nerve within the tragus via the electrodes, to thereby modulate the vagus nerve.

The utility model relates to a multifunctional red light irradiation device which is characterized by comprising a red light irradiation assembly which is used for irradiating fundus by using red light so as to carry out myopia physiotherapy; the fundus imaging assembly is used for imaging the fundus; the lens cone is used for packaging at least one of the red light irradiation assembly and the fundus imaging assembly, and in the lens cone, the red light irradiation assembly and the fundus imaging assembly share part of optical assemblies so as to irradiate the fundus and / or image the fundus. According to the red light irradiation device, by sharing part of the optical assemblies, the fundus red light irradiation assembly and the fundus imaging assembly can be integrated on a single device at the same time, and therefore the multiple functions of conducting red light irradiation on the fundus, conducting imaging on the fundus and the like are achieved.

The present invention relates to LSD1 inhibitors for use in the treatment of NF1-mutant tumors, i.e. Tumors having one or more mutations or genetic alterations that affect the NF1 gene. The invention also provides a method of treating an NF1-mutant tumor in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of an LSD1 inhibitor.

Systems and methods are disclosed for analyzing data from oncology treatments such as immune checkpoint inhibitor or radiotherapy therapies, including predicting adverse events of the oncology therapies, predicting objective response of the oncology therapies, predicting symptoms from the oncology therapies, and use of such predictions by technological implementations to achieve improved system and medical outcomes. An example technique for generating a predicted treatment outcome includes: receiving patient data for a human subject, which provides patient-reported outcomes collected from the human subject relating to a particular oncology treatment; processing the patient data with a trained artificial intelligence (AI) prediction model, which receives the patient data as input and produces a prediction of a treatment outcome as output; and outputting data to modify a treatment workflow of an oncology treatment for the human subject, based on the prediction of the treatment outcome.

The invention belongs to the technical field of medical health care equipment, and particularly provides a treatment control method of an intelligent self-adaptive wave conduction health care instrument, which comprises the following steps of: acquiring a physiological state signal of a user in real time, and generating an abnormal trigger instruction when the physiological state signal is detected to deviate from a preset health threshold range; inputting physiological index data corresponding to the abnormal trigger instruction into a dynamic adjustment model, wherein the dynamic adjustment model generates a treatment scheme based on a mapping relation between physiological indexes and wave conduction parameters; generating a driving control signal according to the treatment scheme, wherein the driving control signal is used for adjusting a particle resonance wave output device in the wave conduction health care instrument; and outputting a target particle resonance wave through a particle resonance wave output device according to the resonance frequency and the amplitude corresponding to the driving control signal, and continuously driving the action duration corresponding to the control signal. By collecting the physiological state signal of the user in real time and dynamically comparing the physiological state signal with the preset health threshold value, accurate anomaly detection and immediate intervention are achieved, and the limitation of fixed parameter output of traditional equipment is broken through.

Systems and methods are provided for evaluating a patient for a neurological movement disorder. A three-dimensional medical image of a brain of the patient is captured and provided to an artificial neural network having at least one convolutional layer to provide a set of output values. The set of output values is provided to a machine learning model to provide a clinical parameter representing one of a presence of the neurological movement disorder in the patient and a response of the patient to a specific treatment for the neurological movement disorder.

A counterbalanced imaging device is provided and includes an imaging source and an imaging detector. The counterbalanced imaging device also includes a gantry ring that physically supports the imaging source and the imaging detector. The gantry ring also enables the imaging source and the imaging detector to simultaneously rotate about a center of rotation. The gantry ring may also comprise a detachable segment having one or more counterbalance measures contained therein to align a center of gravity of the gantry ring with the center of rotation when the detachable segment is mounted onto the gantry ring.

The invention relates to the technical field of medical robots, in particular to a laser treatment auxiliary robot and an auxiliary method thereof, and the method comprises the following steps: scanning a motion area, and obtaining obstacle detection records by calculating point cloud density, boundary form and curvature change parameters and identifying obstacles in the motion area. According to the method, through multi-layer point cloud scanning, the recognition precision of the mechanical arm on the obstacles in the movement area is optimized, the space sensing capacity is improved, the real-time data of the joint torque sensor are combined, the accuracy of collision risk assessment is enhanced, the speed and torque are dynamically adjusted, and the movement safety and stability are improved; according to the method, treatment starting coordinates are extracted by adopting tissue deformation in unit time, a surface curvature change value and a boundary shortest distance, the matching degree of a treatment area is improved, laser treatment is more accurate, a motion path is optimized by combining a surface geometrical shape and real-time operation feedback, trajectory mutation is reduced, and safety and consistency of a treatment process are improved.

This disclosure describes methods and systems for preventing, moderating, and / or treating brain injury. The methods herein may include obtaining a test result reflecting a condition of a brain in the subject, determining a stimulation parameter based on the test result, and stimulating a nerve based on the stimulation parameter, wherein stimulation of the nerve assists or causes contraction of a respiratory muscle in the subject. The systems herein may include a processor configured to: receive a test result reflecting a condition of a brain in a subject, and determine a stimulation parameter based on the test result; and a stimulator configured to stimulate a nerve based on the stimulation parameter, wherein stimulation of the nerve assists or causes contraction of a respiratory muscle in the subject.

To provide a system useful for reducing a visual effect displaying undesirable laser-induced emission during endoscopic, low-invasive or another surgical treatment.SOLUTION: A system for endoscopically imaging a first target of a patient, using a light source and a light detector, and for laser-treating a same or different second target of the patient, using a laser source, the system is provided. For example, the system can have at least signal processing circuitry, which can include a target response signal laser-source flashing component detector and a flashing analyzer.SELECTED DRAWING: Figure 1A

A device for detecting and analyzing vital fields includes: a dielectric barrier discharge array fabricated on a thin substrate with low dielectric loss; an air permeable sheet for electrical insulation from the skin; a transformer for generating sufficient AC voltage to cause air breakdown in the array; a signal transformer and bypass capacitor for isolating the radio frequency current from the plasma discharge; circuitry for amplification and narrow-band spectrum analysis of the plasma discharge current. The amplified signal from the plasma discharge current is gated to include only signal from the part of the drive waveform where plasma discharge predominantly occurs. Frequency converters reduce the complexity of narrow-band spectrum analysis; spectrum analysis is done by Fast Fourier Transform analysis of the frequency converter outputs. The different FFT results are compared and analyzed to aid the user with the correct array placement on the body, and the detection of medical conditions.

The high-frequency power calibration system comprises an illuminometer module, a voltage regulator module, a standard load module, a high-frequency source placement frame, a high-frequency current acquisition module, a control system and a computer, and all the modules are connected through signals to form the complete calibration system. The calibration method comprises the steps of load impedance standard power data acquisition, high-frequency power data acquisition, high-frequency power precision verification and high-frequency source module numbering and calibration data configuration. According to load impedance standard power data acquisition, different power frequency voltages are set, power frequency power and illuminometer data are acquired, and a relation function between the power frequency power and the illuminometer data is established; in high-frequency power data acquisition, different DA voltages are set, illuminometer data are acquired, and a relation function is established; the high-frequency power precision verification verifies the power precision by fitting the function relationship; and finally, the calibration data and the high-frequency source module number are correspondingly stored. The problem that the power calibration precision of the in-vitro high-frequency thermal therapy machine is insufficient is solved.

The invention provides a terahertz intelligent energy cabin, and relates to the technical field of health maintenance equipment. The energy cabin comprises a cabin body, and a plurality of functional modules in the cabin, such as a massage assembly, a terahertz wave emitter, a quantum biological resonance assembly, a gyromagnetic recuperation assembly, a negative oxygen ion generation assembly, a biological brain wave monitoring assembly, a sound therapy system, a micro-pressure oxygen supply assembly and the like. All the modules are electrically connected with the intelligent control module, the intelligent control module integrates a multi-mode fusion intelligent evaluation model and a self-adaptive closed-loop regulation and control model, multi-source data can be processed, parameters of all assemblies can be dynamically adjusted, and cooperative operation of the system is guaranteed. According to the invention, the multi-functional module is integrated, cooperative operation and dynamic regulation and control are realized through the intelligent control module, multi-dimensional, personalized and intelligent comprehensive recuperation can be realized, and the modern health management requirements are met.

The invention discloses nuclear drug injection automatic drug delivery equipment which comprises a drug delivery equipment body and an accurate drug delivery system. The precise dosing system specifically comprises a liquid medicine processing module, a liquid medicine feeding module and a liquid medicine feeding module, wherein the liquid medicine processing module is responsible for full-flow control of extraction, dilution, compensation and injection of liquid medicine; the sensor and detection module is used for collecting the physical property parameters, the flow state and the in-vivo and in-vitro radioactive dose of the liquid medicine in real time; the data processing and control module is used for dynamically calculating the compensation amount, predicting the residual amount and executing safety control; the safety and exception handling module is used for monitoring exceptions in real time and triggering safety braking; the data storage and communication module is used for storing operation data and supporting remote supervision; and the user interface and monitoring module is used for providing operation interaction and real-time state display. According to the invention, through the core technologies of dynamic concentration compensation, tube wall residue prediction, bimodal monitoring, block chain evidence storage and the like, a set of nuclear drug injection administration system with full-process automation, high precision and high safety is constructed.