1782results about "Radiation therapy" patented technology

Disclosed in the present invention are a helium-neon laser therapy method and application based on adaptive beam focusing. The technical method belongs to the technical field of medical lasers, and realizes adaptive beam focusing optimization for helium-neon laser therapy. The process comprises: patient assessment, which involves acquiring an image and data of a treatment region; image processing and analysis, which involves performing feature extraction and lesion segmentation by using a convolutional neural network (CNN) and a U-Net algorithm; laser parameter setting based on wavefront optimization, which involves adjusting laser parameters by means of a feedback control system; therapy execution, which involves tracking and adjusting a beam in real time by means of wavefront optimization and an optical flow algorithm; result assessment and adjustment, which involves assessing a treatment effect by using the CNN and the U-Net algorithm again, and adjusting the laser parameters for repeated treatments if necessary; and finally, assessing a treatment result for the patient after the treatment is completed. The method improves the accuracy, effect and safety of treatment, and increases the degree of satisfaction of a patient.

The present application relates to a real-time three-dimensional (3D) tumor tracking method and apparatus, and a computer device and a storage medium. The method comprises: acquiring a moving image and a reference image of a tumor site; performing hybrid data enhancement on the moving image and the reference image, so as to obtain a 3D CT image that represents each respiratory phase, and a segmented moving image; projecting the 3D CT image by using a ray casting algorithm, so as to generate a 2D DRR at a corresponding moment; and inputting the 2D DRR into a trained tumor tracking network, outputting a 3D deformation field of the 2D DRR by means of the tumor tracking network, and making the 3D deformation field act on the reference image, so as to generate a predicted segmented tumor image of the 2D DRR at the corresponding moment. In the embodiments of the present application, tumor tracking is performed on the basis of a single-angle X-ray image, such that the radiation dose is greatly reduced, high-precision tumor tracking performed at a low dose is realized, and the tumor tracking speed is significantly increased.

Antibiotic for use in a method comprising systemically administering a photosensitive antibiotic to a subject having a microbial infection in a target tissue to provide a blood plasma concentration of the antibiotic in the subject; allowing the plasma or tissue concentration of the antibiotic increase to a predetermined level; and subjecting the target tissue to photodynamic therapy in order to increase the antimicrobial action of the antibiotic in the target tissue. With light activation the efficacy of the photosensitizer antibiotic can be enhanced, the spectrum of the microbial effect broadened and even an antiviral effect can be obtained. Generally, the present invention can be exploited when there is a need for enhancement of the local antimicrobial effect of antibiotics.

Hydrogen-bonded framework nanoparticles comprising a chemiluminescent compound (e.g., L-012) are provided and can be used, e.g., for sono-optogenetic treatment of neurodegenerative diseases such as Parkinson's disease. Related in vivo and therapeutic methods are also provided.

Devices and methods are disclosed for treating tissue with microwave energy. Such devices and methods are able to treat cavities or surface tissue by creating one or more area or volumetric lesions. Also disclosed are flexible, low-profile devices that can be inserted non-invasively or minimally invasively near or into the target tissue as well as microwave antennas designed to generate ablation profiles that can ablate a large area or a large volume of target tissue in a single ablation. The devices include antennas wherein the field profile generated by an antenna is tailored and optimized for a particular clinical application. The antennas use unique properties of microwaves such as interaction of a microwave field with a metallic object and the use of additional shaping elements to shape the microwave field.

The present disclosure generally relates to materials, processes, generators, and / or systems, for generating radioisotope. The present disclosure also generally relates to ceramic materials comprising radioisotope suitable for use in a radioisotope generator. The present disclosure also generally relates to processes, generators and / or systems, for producing and capturing radioisotope. The present disclosure also generally relates to the preparation of radioisotope solutions for use in radiopharmacy and / or other clinical applications.

A method and system for intelligent plan optimization. The method may include: obtaining a sample scan image, one or more sample contour images, and sample dose data by resampling a scan image, a contour image, and dose data at a same resolution; obtaining a weighted image by the one or more sample contour images; obtaining a sample weighted image by performing a dimensionality reduction on the weighted image; obtaining a trained regression model by performing a regression training on an initial regression model based on the sample scan image, the contour image of the sample target region, the sample weighted image, and the sample dose data corresponding to the sample scan image; and obtaining a dose prediction result by inputting a to-be-tested scan image, a to-be-tested contour image of the target region, and a to-be-tested weighted image after the dimensionality reduction into the trained regression model.

One ECR ion source generates a He < 2 + > ion beam, the other ECR ion source generates a H2 < + > ion beam, the He < 2 + > or H2 < + > ion beam is selected by a deflection magnet and then transmitted and focused by LEBT to enter an RFQ, the focusing factor of the RFQ is increased and then reduced, DTL is IH-DTL designed by adopting KONUS beam dynamics and comprises two KONUS periods, the working frequencies of the RFQ and the DTL are respectively 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, 425MHz, after He < 2 + > or H2 < + > ion beams are accelerated by RFQ and DTL, the MEBT distributes and transmits the ion beams to a downstream accelerator and an isotope production device. According to the proton helium ion implanter provided by the invention, the particle beam can meet the injection requirement of a subsequent synchrotron, the miniaturization of the proton helium ion implanter is realized, and the production of medical isotopes is considered.

The invention discloses a hidden multi-mode brain state real-time monitoring and closed-loop intervention system, and relates to the technical field of intelligent wearable equipment. The system comprises a cap body, and further comprises a multi-point electrode array used for collecting EEG (electroencephalogram) signals, EOG (eye movement) signals and EMG (electromyography) signals of a human body; the brain blood oxygen monitoring module is used for monitoring brain blood oxygen saturation; the signal receiving and processing module is used for preprocessing and analyzing data acquired by the multi-point electrode array and the brain blood oxygen monitoring module; the multi-mode stimulation module is used for implementing sensory and nerve stimulation on the user according to a judgment result of the state judgment module so as to intervene in a drowsiness or attention decline state; and the power supply module and the communication unit are used for providing a working power supply for the modules needing power supply in the system and carrying out data communication with external terminal equipment. The system can monitor the waking degree of the user with high precision and carry out closed-loop feedback intervention by various stimulation means.

The invention discloses a construction method of a cerebral artery ischemia reperfusion model, and belongs to the technical field of animal models. Three-dimensional positioning coordinates of the middle cerebral artery are obtained through magnetic resonance scanning, the far end of the middle cerebral artery can be accurately positioned, the middle cerebral artery is induced to be blocked after irradiation by setting the blood vessel irradiation position, the rose red dosage and the laser irradiation intensity and time, blood vessel recanalization is caused along with blood impact within 4-5 hours, and finally an ischemia reperfusion model is formed. Compared with a traditional craniotomy electrocoagulation middle cerebral artery (permanent occlusion) and a traditional balloon embolism middle cerebral artery (ischemia reperfusion), the construction method has the advantages that wounds on animals are smaller, the animals are easy to survive, and compared with traditional photochemical induction which can only form infarction lesions on the surface layer of the brain, the method can induce deep brain tissue to form infarction, so that the method has the advantages of being simple and convenient to operate and the like. The method can also be expanded to other brain areas to induce deep vascular occlusion. Meanwhile, the method is also suitable for carrying out model construction on old animals, and the modeling success rate is increased.

The invention provides a flux graph generation method and device and a treatment plan generation method and device, relates to the technical field of computers, and solves the technical problems that a convolutional neural network lacks understanding of detailed information of a CT image, and a flux graph predicted based on the convolutional neural network is too smooth and is greatly different from a real flux graph in related technologies. The method comprises: determining a dose distribution or an initial flux map of a target volume at each of a plurality of field angles, the target volume comprising a target region and an organ at risk; inputting the dose distribution or the initial flux diagram of the target volume at each radiation field angle into a first flux diagram generation model based on a denoising diffusion probability model to obtain a flux diagram corresponding to each radiation field angle; wherein the flux diagram corresponding to each radiation field angle is used for representing the intensity of each small beam in the target volume corresponding to each radiation field angle.

This application discloses a beauty instrument accessory head and a beauty instrument, the beauty instrument accessory head comprising: an outer cover, configured to be detachably connected to a beauty instrument body, and comprising a contact outer surface and a connection outer surface; a conductive member, disposed on the outer cover, and comprising a first end face exposed on the contact outer surface and a second end face exposed on the connection outer surface, the first end face in contact with human skin, and the second end face in contact with a cold compress component of the beauty instrument body; and an elastic member, disposed between the outer cover and the conductive member, one end of the elastic member acting on the outer cover, and the other end of the elastic member acting on the conductive member, allowing the conductive member being attached to the cold compress component.

The utility model belongs to the field of medical instruments, and particularly relates to an integrated radioactive particle protection implanter, which comprises a particle bin for storing a particle short rod, a particle bin seat with a handle, a push needle and a puncture needle, the particle bin seat is connected with the puncture needle through a connecting end, and the particle bin seat comprises an upper bin seat and a lower bin seat. A containing cavity used for containing the particle bin is formed between the upper bin base and the lower bin base, the upper bin base is connected with the handle, the handle, the upper bin base, the particle bin and the lower bin base are sequentially and coaxially provided with material pushing holes allowing the pushing needle to penetrate through, and the discharging ends of the material pushing holes are located on the lower bin base and connected with the connecting end. And the particle bin and the particle bin seat are integrated, so that medical staff are prevented from being affected by radiation in the installation process, and the situation that disputes are generated between hospitals and supply manufacturers due to the fact that the particle short rods are lost is reduced.

An automated clinical decision support method for treatment re-planning that enhances a CBCT scan using information from an initial CT scan of the patient to create a synthetic CT scan; adapts contours of organ(s) and tumour(s) from the initial CT scan to align with the synthetic CT scan; and calculates a delivered radiation dose from the synthetic CT scan; compares these against an original treatment plan to detect deviations exceeding preset thresholds, and triggers alerts with assigned priority levels for a re-plan decision.

Embodiments of systems, devices, and methods relate to initiating beam transport for an accelerator system. An example method includes increasing a bias voltage of one or more electrodes of the accelerator system to a first voltage level and extracting a charged particle beam from a beam source such that the beam is transported through the accelerator system. The beam has a beam current at a first beam current level that results in a first transient voltage drop of the accelerator system within a threshold. The method further includes increasing the beam current at a rate that results in one or more subsequent transient voltage drops of the accelerator system until the accelerator system has reached nominal conditions. The one or more subsequent transient voltage drops are within the threshold. Another example method includes biasing one or more electrodes of an accelerator system to a voltage level and selectively extracting, according to a duty cycle function, a charged particle beam from a beam source such that the charged particle beam is transported through the accelerator system. The duty cycle function can be linear or non-linear and can include a frequency f. The duty cycle function can include a variable pulse duration such that the variable pulse duration increases over time with each selective extraction of the charged particle beam.

A medical device for treating a cancerous tumor comprises an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor. The cancerous tumor comprises a cancerous cell population. The medical device comprises control circuitry in communication with the electric field generating circuit. The control circuitry is configured to control delivery of the one or more electric fields from the electric field generating circuit at or near the site of the cancerous tumor. The medical device comprises one or more electrical leads in electrical communication with the electric field generating circuit. The medical device further comprises a drug delivery catheter for delivery of one or more chemotherapeutic agents. The control circuitry causes the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz at the site of a cancerous tumor located within a bodily tissue. The one or more electric fields are effective to delay mitosis and cause mitotic synchronization within a proportion of the cancerous cell population.

Disclosed in the present invention are a scanning box device and an electron accelerator, the electron accelerator comprising an accelerating tube and a deflection coil; the scanning box device comprising a scanning chamber and a scanning box, wherein the scanning chamber is sealingly connected to the scanning box; the scanning chamber is arranged above the scanning box; the accelerating tube is arranged above the scanning chamber; the deflection coil is arranged on the outer side of the scanning chamber; and the scanning chamber is made of a non-metallic material. The present invention can prevent the generation of eddy currents in the scanning box, thus reducing the problems of energy loss and heat generation, improving the performance and stability of the apparatus.

The invention discloses a robot assisted diagnosis and treatment system for a nuclear medicine ward and an application method. The robot assisted diagnosis and treatment system comprises an AI robot for non-contact assisted diagnosis and treatment; the robot library is arranged on the same layer of the nuclear medicine ward; the remote interaction platform is used for issuing related instructions and man-machine interaction to the AI robot; a radiation protection and monitoring module, an identity recognition module, a health propaganda and education module, a ferry module, a visual doctor-patient communication module, a communication module, an RFID access control module and an environment disinfection module are integrated on the AI robot; the AI robot is connected with an external subcutaneous injection module, an external intravenous injection module, an external medicine distribution module and an external living goods conveying module through corresponding switching assemblies. According to the robot-assisted diagnosis and treatment system for the nuclear medicine ward and the application method, a semi-autonomous and remote interaction mode is used for replacing medical staff to execute face-to-face diagnosis and treatment behaviors with patients, and non-contact diagnosis and treatment are achieved through human-machine-patient high cooperation in the whole diagnosis and treatment process.

A device 100 for developing the concentration, the device 100 comprising: an optical sensor unit, the optical sensor unit comprising a plurality of one or more lenses 201, 202 capable of holding sensitive elements, the plurality of sensitive elements being configured to detect a user-provided biological signal in at least three operating modes; three switches for switching between the plurality of operating modes; a plurality of illumination units configured to indicate each of the plurality of operating modes by emitting a predetermined light signal; a processing unit for processing information using artificial intelligence.

A neurostimulation system may include an implantable neurostimulator. An implantable neurostimulator may include a first sensor configured to sense internal data relating to a symptom of a neurological movement disorder of a patient. An implantable neurostimulator may include an internal stimulator configured to provide an internal stimulation output to an internal target area of a patient. An implantable neurostimulator may include a first wireless communication device configured to communicate internal data with a network. A neurostimulation system may include a wearable neurostimulator. A wearable neurostimulator may include a second sensor configured to sense external data of a patient. A wearable neurostimulator may include an external stimulator configured to provide an external stimulation output to an external target area of a patient. A wearable neurostimulator may include a second wireless communication device configured to communicate external data with a network and receive internal data from the network.

Disclosed herein is a waveguide cell having a helical cavity. The waveguide cell has a central axis and a cavity having a transverse cross section whose rotational position about the central axis varies along the central axis. There is also disclosed a method a determining the shape of a waveguide cell.

A method of treating non-melanoma skin cancer in a patient in need thereof is provided. The method includes administering a hedgehog pathway inhibitor to the patient and applying to a region of skin on the patient, a topical composition comprising 5-aminolevulinic acid, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient. The method further includes incubating the topical composition on the region of skin; and illuminating the region of skin with a light source at an irradiance density of 20 mW / cm2.

Disclosed herein is a method for generating one or more synthetic electron density, sED, images. The method comprises obtaining a first image of a first imaging modality, the first image depicting an anatomical region of a subject. The method also comprises generating, using a trained machine learning model and the first image, a sED image depicting the anatomical region, wherein the trained machine learning model has been trained using a set of training images comprising a first subset of training images of the first imaging modality, and a second subset of training images in which each training image comprises electron density, ED, information.

Devices and methods for tissue treatment produce a mechanical stimulation therapy and electromagnetic field therapy. The mechanical stimulation therapy provides stimulation of blood circulation and stimulates treated cells. The electromagnetic field enables thermal treatment of tissue. Combination of both therapies improves soft tissue treatment, mainly connective tissue in the skin area and fat reduction.

The invention relates to a method of MR imaging of a body (10) of a patient positioned in an examination volume of an MR device (1). It is an object of the invention to provide a method that enables geometrically correct MR-only radiation therapy planning at minimum scan times. The method of the invention comprises the following steps: acquiring first MR imaging data representative of at least one region of the body (10); analyzing said first MR imaging data to delineate at least one anatomical structure within said body region; acquiring second MR imaging data of said body region using a multi-point Dixon sequence; deriving a B0 map from said second MR imaging data; analyzing said B0 map to determine at least one low fidelity region of said B0 map; performing B0 mapping to refine the B0 map using a multi-acquisition gradient echo sequence restricted to at least one region where said delineated anatomical structure and said low fidelity region overlap completely or partially; and correcting geometrical distortions in said first and / or second MR imaging data using the refined B0 map. Moreover, the invention relates to a MR device (1) for carrying out the method, and to a computer program to be executed on a MR device (1).

A non-transitory computer readable medium (26s) stores instructions executable by at least one electronic processor (14s) to perform a method (100) of monitoring a quality assurance (QA) procedure performed using a medical device (2). The method includes receiving a signal indicating a start of the QA procedure; analyzing video (17) of the medical device acquired after receiving the signal to detect one or more errors during the QA procedure; and providing a remedial action addressing the detected one or more errors.

The invention provides a compact synchrotron vacuum system and a design method, and relates to the technical field of particle acceleration. The vacuum system comprises a first vacuum unit and a second vacuum unit, the first vacuum unit comprises at least two first beam deflection vacuum tubes, and the adjacent first beam deflection vacuum tubes are connected through a first beam regulation and control vacuum tube; the second vacuum unit comprises at least two second beam deflection vacuum tubes, and the adjacent second beam deflection vacuum tubes are connected through a second beam regulation and control vacuum tube; a second beam deflection vacuum tube at one end of the second vacuum unit is connected with a first beam regulation vacuum tube at the first end of the first vacuum unit, and a second beam deflection vacuum tube at the other end of the second vacuum unit is connected with a first beam regulation vacuum tube at the second end of the first vacuum unit; and a beam diagnosis element is arranged in the first beam regulation and control vacuum tube of the first vacuum unit, so that the perimeter of the vacuum system can be shortened, and the popularization difficulty of the medical accelerator treatment device in small and medium-sized medical institutions is reduced.

The quantitative injection device structurally comprises an injection cylinder, a piston shaft, a finger hooking part, scale marks, a pressing handle, a needle sleeve and a needle head, a sliding block can slide up and down on the side face of a cylinder pipe, a sinking strip is squeezed while sliding, a plastic plate is ejected out by an arc-shaped plate to be bent inwards, and therefore it can be known that the quantitative injection device is convenient to use. The plastic plate is bent inwards in an arc mode to damage the circular state of the inner side of the tube, then when the piston shaft pushes the medicine in the tube, the medicine is blocked by the inwards-bent part of the plastic plate, and therefore the medicine in the tube is pushed to flow from the inside of the flow opening to the needle head by manually pressing the piston shaft through the pressing hand, and the lowermost end of the piston shaft is blocked by the plastic plate extruded by the sliding block. Further, the pushed volume of the medicament is the height of the sliding block, and the sliding block slides by the height by aligning the indicating line with the scale line, so that the sliding block slides according to the injection amount of the medicament, accurate quantitative injection is realized, and the situation that the injection amount is too large or too small easily caused by hand pushing is prevented.

A vagus nerve stimulation system for stimulating a vagus nerve in a biological subject, the system including a clip configured to be attached to a tragus of the subject, the clip including opposing arms configured so that a distal end of the arms are biased towards each other and electrodes positioned proximate a distal end of the arms on opposing faces so that the electrodes are urged into engagement with opposing faces of the tragus and a signal generator electrically connected to the electrodes, the signal generator being configured to generate at least one therapy signal that is applied to the vagus nerve within the tragus via the electrodes, to thereby modulate the vagus nerve.

The utility model relates to a multifunctional red light irradiation device which is characterized by comprising a red light irradiation assembly which is used for irradiating fundus by using red light so as to carry out myopia physiotherapy; the fundus imaging assembly is used for imaging the fundus; the lens cone is used for packaging at least one of the red light irradiation assembly and the fundus imaging assembly, and in the lens cone, the red light irradiation assembly and the fundus imaging assembly share part of optical assemblies so as to irradiate the fundus and / or image the fundus. According to the red light irradiation device, by sharing part of the optical assemblies, the fundus red light irradiation assembly and the fundus imaging assembly can be integrated on a single device at the same time, and therefore the multiple functions of conducting red light irradiation on the fundus, conducting imaging on the fundus and the like are achieved.