An electro-mechanical 
surgical device includes: a housing; an elongated shaft extending from the housing, a distal end of the elongated shaft being detachably coupleable to a 
surgical instrument; at least two axially rotatable drive shafts disposed within the elongated shaft, a distal end of each of the drive shafts being configured to couple with the 
surgical instrument; a steering cable arrangement, the steering cable arrangement being configured to steer the distal end of the elongated shaft; and a 
motor system disposed within the housing, the 
motor system being configured to drive the drive shafts and the steering cable arrangement. A 
control system may be provided for controlling the 
motor system. A 
remote control unit may also be provided for controlling the motor 
system via the 
control system. Sensors, such as optical or Hall-effect devices, may be provided for determining the position of the elements of the 
surgical instrument based on the detected rotation of the drive shafts. A memory unit stores a plurality of operating programs or algorithms, each corresponding to a type of surgical instrument attachable to the electro-mechanical 
surgical device. The 
control system reads or selects from the plurality of operating programs or algorithms, the operating program or 
algorithm corresponding to the type of surgical instrument attached to the electro-mechanical 
surgical device.