74 results about "Tissue temperature" patented technology

Systems and methods for safety assessment before and during a transcranial ultrasound (TUS) procedure are described. A neuronavigation system is used to determine the probe's position and orientation. The probe's location and the subject's head MRI data are used to simulate the acoustic field within the subject's head. The acoustic field is overlaid on the MRI data and displayed to a clinician for evaluation. The phases of the transmit voltages are adjusted to optimize the location of the peak of the acoustic field to match the targets in the subject's brain. Before and during TUS, the spatial distribution of tissue temperature, MI, TIC, and ISPTA are computed and displayed to the clinician. Acoustic field changes due to the subject's movement are detected, and the TUS operation is terminated if the stimulated acoustic field becomes off-target. Monitoring circuits shut down the neuromodulation if parameters are out-of-range.

The invention discloses a medical oncology implantable infusion port leakage monitoring system and method, and relates to the technical field of infusion leakage detection. The multi-parameter sensor module is used for monitoring pressure fluctuation in an infusion port, sensing temperature change of surrounding tissues, detecting abnormal leakage conditions of medicine components and obtaining multi-parameter sensor data; the flexible electronic circuit module is used for processing multi-parameter sensor data in real time; the data analysis and early warning module is used for performing real-time analysis on the processed multi-parameter sensor data and performing graded early warning; and the wireless communication module is used for transmitting the data of the multi-parameter sensor to an external terminal in real time by adopting a wireless communication technology. The invention relates to data acquisition, signal processing, feature extraction and fusion, leakage threshold judgment and response and feedback of an alarm mechanism, the accuracy of sensor data is ensured by applying a multi-modal fusion algorithm, and the safety and medical response efficiency of a patient are improved through a graded early warning mechanism.

The invention discloses an interventional therapy path planning system based on ultrasonic imaging, and relates to the technical field of interventional therapy systems.An image acquisition module acquires a two-dimensional or three-dimensional ultrasonic image of an operation area, and standardized input of image data is achieved; the structure identification module executes a medical image segmentation task based on the ultrasonic image and identifies a key anatomical structure in the image; the geometric modeling module constructs a three-dimensional space model according to the structure recognition result; the thermal simulation prediction module comprises a heat conduction simulation sub-module and a thermal parameter dynamic adjustment sub-module; the temperature feedback module reconstructs a three-dimensional temperature field image in the target tissue based on the tissue temperature feedback signal; the parameter updating module executes real-time updating of heat conduction parameters based on the residual error between the predicted temperature field and the observation temperature field collected by the temperature feedback module; the problems that in existing interventional therapy, thermal control precision is low, path planning depends on experience, and tissue dynamic changes are difficult to deal with are effectively solved.

The invention belongs to the technical field of medical equipment, and provides a bipolar electrotome control method and device, electrosurgical equipment and a storage medium, and the method comprises the steps: obtaining an output voltage, an output current and a tissue temperature; determining a feature vector based on the output voltage, the output current and the tissue temperature; inputting a plurality of feature vector values in the feature vectors into a trained full-connection neural network to obtain a closure degree predicted value, a carbonization risk predicted value and a quality score predicted value; determining a dynamic output power based on the closure degree predicted value, the carbonization risk predicted value, a feature vector and a basic output power; based on the dynamic output power and a preset condition, determining a safe output power through a safe output power calculation formula; controlling the closing action of the bipolar electrotome based on the closing degree predicted value, the safe output power and the closing quality score value; the efficiency of controlling the bipolar electrotome to perform the closing action is improved, the problem of excessive carbonization of tissues is reduced, and the operation safety is greatly improved.

There is provided a process for treatment of rhinitis by diode laser ablation of the branches of the posterior nasal nerve. The diode laser delivery device with elongated fiber optic with its fiber tip is inserted through a patient's nostril and has the length, flexibility and a curvature to reach both above and under the patient's middle turbinate for treatment of both branches of the posterior nasal nerves. Skin and tissue temperature is raised to approximately 60-70° C. with the process. A control knob on the laser delivery device moves from a first to a second position to move a camera attached to the laser delivery device. The fiber optic includes a distal fiber tip extending from a malleable sheath connected to the body for delivering light energy to a treatment area.

The invention discloses a radio frequency thermal therapy equipment testing system, relates to the technical field of equipment testing, and is used for solving the problems that the uncertainty in the energy transmission process is increased, and the system output stability and response precision are reduced. The output power is calculated in combination with an analog multiplier, and difference analysis is carried out in cooperation with ideal power; meanwhile, performing fast Fourier transform on the original signal to extract a frequency concentration ratio, and calculating a heat concentration coefficient; the tissue temperature at a needle is monitored based on an optical fiber fluorescence sensor, fluorescence detection temperature and observation temperature values are calculated in combination with fluorescence lifetime, difference analysis is performed to obtain a thermal response deviation factor, and the two values are fused to obtain a feedback calibration result for equipment performance optimization, and real-time monitoring of an energy state and abnormal heat accumulation identification are realized.

Systems and methods for ablating target tissue, measuring parameters during ablation such as temperature of the target tissue, and predicting volume of the ablation based on the measured parameters are provided. The system may include a switching antenna for both heating of target tissue and radiometry to monitor the temperature of the heated tissue, and a processor for calculating the temperature of the target tissue, segmenting medical images, and predicting volume of the ablation based on radiometric signals indicative of the target tissue temperature. The predicted ablation volume may be adapted to account for tissue boundaries and anatomical structures. The processor further may determine properties of the target tissue such as tissue type.

The invention relates to nervonic acid-loaded near-infrared light response type injectable hydrogel as well as a preparation method and application thereof, and belongs to the technical field of biological engineering. According to the invention, P (NIPAM-co-NHMAM) and a modified natural polymer material are combined to prepare a temperature-responsive hydrogel capable of realizing reversible volume shrinkage / expansion at a specific temperature, near-infrared light physiotherapy and irradiation are combined to damage local skin, and the hydrogel is stimulated to realize reversible volume deformation by controlling tissue temperature, so that the temperature-responsive hydrogel can be used for preparing the hydrogel with the reversible volume shrinkage / expansion at the specific temperature. Therefore, accurate and wireless space-time regulation and control of nervonic acid release behaviors are realized. Therefore, the nervonic acid loaded near-infrared light response type injectable hydrogel disclosed by the invention can realize efficient carrying and light response controllable release of nervonic acid, promotes functional recovery after spinal cord injury, and has a relatively good application prospect and research significance.

The utility model discloses a plasma operation electrode cutting in-vitro tissue temperature test platform, which comprises a plasma host, a plasma operation electrode, a temperature measurement console, a temperature recorder, a time synchronization controller and a computer, and is characterized in that the plasma operation electrode is connected with an operation electrode interface of the plasma host through a lead; according to the test platform, the plasma operation electrode can be conveniently clamped and fixed by arranging the adjusting sliding block, the annular clamping frame and the anti-skid layer, and the spatial position of the plasma operation electrode clamped and fixed by the electrode clamping mechanism can be conveniently and accurately adjusted in the x direction, the y direction and the z direction by arranging the supporting column, the connecting sleeve, the connecting block, the positioning bolt and the connecting rod; the depth of the plasma operation electrode tool bit fixed on the electrode clamping mechanism inserted into the in-vitro tissue and the distance between the plasma operation electrode tool bit and the temperature measuring probe can be conveniently controlled, so that temperature data of different depths in the in-vitro tissue can be conveniently measured, and the temperature of the in-vitro tissue can be conveniently and accurately measured.

The invention discloses a pressure monitoring device and method for evaluating pressure sore risk, and relates to the technical field of medical equipment. The system comprises a pressure sensing unit used for collecting pressure distribution data between the body surface of a patient and a supporting surface; the distance measuring device is used for measuring the distance between the device and the body surface of the patient. According to the method, information of three different dimensions of pressure distribution, body surface image and deep thermal imaging is subjected to fusion analysis, a pressure sensor positions a high-risk pressed area, a high-definition color image is used for identifying macroscopic skin damage and color change, infrared thermal imaging can penetrate through a surface layer, and the image can be used for identifying the skin damage and color change. According to the method, deep tissue temperature abnormity caused by ischemia and inflammation is sensitively captured, and the three types of information are integrated into a quantitative comprehensive risk score through a weighting algorithm, so that an evaluation result does not depend on subjective experience of nursing personnel any more and is converted into objective and quantifiable accurate diagnosis, and the screening accuracy of high-risk patients is remarkably improved.

A method for controlling tissue temperature involves providing a nasal cannula including a first elongated prong with an axial fluid channel and a downwardly-curved shape. The nasal cannula further includes a first aperture on a side wall of a distal portion of the first elongated prong. The first aperture provides access to the axial fluid channel. The method includes inserting the first elongated prong into a nasal cavity of a subject to face the first aperture at a pharyngeal wall of the subject and modifying a temperature of the pharyngeal wall by delivering a first fluid portion through the axial fluid channel and out of the first aperture to the pharyngeal wall.

The present invention provides a high-peak tunable thulium-doped fiber laser system based on supercapacitor energy supply, which involves the use of stimulated emission modulation technology. It intelligently selects the most suitable laser output mode according to the hardness of the stone and the blood oxygen status of the tissue; and automatically switches to the thulium laser continuous wave hemostasis mode when the hemoglobin deoxygenation ratio and tissue temperature rise exceed the standard to ensure surgical safety; secondly, combined with supercapacitor energy supply technology, the system has high-peak and low-latency energy release capabilities, significantly improving the lithotripsy efficiency. At the same time, through a closed-loop control mechanism, the laser parameters are fine-tuned in real time to avoid the "flash" phenomenon and reduce surgical risks.

In part, the disclosure relates to an electromagnetic radiation (EMR) delivery system for non-invasive surface tissue temperature monitoring. The system includes a first source of EMR having a first wavelength range; a second source of EMR having a second wavelength range; and a tissue contacting material comprising a set of wavelength range specific EMR responsive dopants. In various embodiments, the tissue contacting material is positioned on a surface of a target region of tissue, wherein the tissue contacting material receives EMR from the first source, wherein the tissue contacting material receives EMR from the second source. The first and second sources may be arranged in different ori-entations or along a common axis or orientation.

Systems and methods for measuring cable pollution to accurately measure parameters during ablation such as temperature of the target tissue for safe and efficacious ablation of target tissue are provided. For example, the systems described herein comprise a switch, e.g., a Dicke switch, a radiometer, and a reference termination positioned at a proximal side of a coaxial cable connecting a generator to a catheter comprising a microwave antenna, and a diode circuit positioned at a distal side of the coaxial cable, e.g., within a handle of the catheter. The diode circuit may be biased to a closed state to create a short circuit at the distal end of the cable to thereby isolate the contribution of the cable to the radiometric signals traveling through the cable, e.g., cable pollution, which may be used to compute the target tissue temperature.

The invention relates to a method for determining a switch-off time for a medical device, comprising the steps of measuring the duration of a tissue temperature above 85°C, preferably above 95°C, preferably calculating online the average temperature from the first time the temperature reaches 85°C, preferably 95°C, measuring and / or calculating the energy input until the temperature reaches 85°C, preferably 95°C, and preferably below 110°C, preferably below 100°C, and calculating a parameter SP that correlates the above results and switches off at a predetermined value. The invention also relates to a medical device, a use, and a storage medium according to the coordinated claims.

A system includes an energy-based surgical instrument having an end effector with two electrodes. One of the electrodes has multiple electrode portions. A generator coupled to the surgical instrument supplies radio frequency (RF) energy to the electrode portions for a tissue coagulation process, and further supplies RF energy at a higher voltage or current to the other electrode portion for a tissue transection process. Control elements monitor tissue impedance or tissue temperature. Other embodiments are described and claimed in this invention.

The invention discloses a multi-sensor joint feedback radiofrequency ablation morphology prediction system, and relates to the technical field of radiofrequency ablation minimally invasive therapy, and the system specifically comprises an ablation signal collection module which processes a signal through a distributed temperature sensor and an impedance detection path and through low-pass filtering and moving average processing; reconstructing a continuous and smooth tissue temperature field from the discrete temperature data; the core parameter calculation module is used for calculating core state parameters based on the temperature field and impedance data, setting a dynamic carbonization threshold value and a carbonization risk index, constructing a real-time necrosis degree index, presenting a necrosis area through a thermodynamic diagram and defining an ablation front edge; and the power self-adaptive closed-loop regulation and control module is used for predicting tissue state change, solving optimal test power through a target optimization function, adding carbonization risk constraint and power boundary limitation, dynamically adjusting output power, periodically updating tissue state data and repeating the whole process to form a closed loop so as to realize self-adaptive regulation and control of the ablation process.

A surgical device includes a handle including at least one user input mechanism and a shaft extending distally from the handle, the shaft including a distal end. In an example, a thermal assembly may be operably coupled to a distal end of a shaft, the thermal assembly including a heating element, where the thermal assembly includes at least one heating element and is electrically coupled to at least one user input mechanism. In an example, a temperature monitoring mechanism may be coupled to a handle, where the temperature monitoring mechanism includes a temperature monitoring technique such that a temperature of at least one of a thermal assembly or a target tissue region of a patient is monitored during a procedure performed with a surgical device, where the temperature monitoring technique includes a fiber Bragg grating technique.

The present invention relates to a treatment device using RF energy and a control method thereof, and provides a treatment device using RF energy and a control method thereof, the treatment device comprising: an RF generation unit; an electrode unit that comes into contact with the skin of a patient and applies, to tissue, a plurality of RF pulses generated from the RF generation unit; a temperature measurement unit for measuring temperature information of the tissue, to which the RF pulses are being applied, while the RF pulses are being applied; and a control unit for controlling parameters of the RF pulses on the basis of the temperature information measured by the temperature measurement unit.

The invention provides methods and compositions for treatment of pain, such as joint pain, using capsaicin in a procedure that attenuates transient burning sensation experienced by patients due to capsaicin administration. The methods desirably provide relief from joint pain, such as osteoarthritic knee joint pain, for an extended duration, such as at least about 3 months, 6 months, 9 months, or 1 year. To attenuate the adverse side effect of a transient burning sensation caused by capsaicin-induced neuronal excitation, the methods utilize a cooling article, such as a material wrap cooled via a circulating fluid, to reduce the temperature of tissue to be exposed to capsaicin to within a certain range for certain durations of time, optionally in combination with administering a local anesthetic agent, resulting in the substantial reduction or even elimination of transient burning sensation caused by capsaicin.

The invention provides a high-peak tunable thulium-doped fiber laser system based on energy supply of a super capacitor, relates to the technical field of modulation by utilizing stimulated emission, and intelligently selects a most suitable laser output mode according to the hardness of stones and the blood oxygen state of tissues; when the hemoglobin deoxidation ratio and the tissue temperature rise exceed the standard, the mode is automatically switched to the thulium laser continuous wave hemostasis mode, and the operation safety is ensured; secondly, in combination with a super-capacitor energy supply technology, the system has high-peak and low-delay energy release capacity, the lithotripsy efficiency is remarkably improved, meanwhile, laser parameters are finely adjusted in real time through a closed-loop control mechanism, the explosion flash phenomenon is avoided, and the surgical risk is reduced.

The ablation electrode with the temperature prompting function comprises a handle, a plug is arranged at one end of the handle, a cutter bar is arranged at the other end of the handle, a loop electrode, an insulator and a working electrode are arranged at the front end of the cutter bar, and a temperature feedback mechanism is further arranged at the front end of the cutter bar. And the temperature feedback mechanism displays a visible signal at the front end of the cutter bar. According to the technical scheme, the temperature feedback mechanism is arranged at the front end of the cutter bar, and when the temperature exceeds the preset value, the temperature feedback mechanism displays a visual signal at the front end of the cutter bar, so that a doctor can visually receive a temperature prompt under an endoscope; therefore, the purpose of prompting the temperature of fluid or tissue around the ablation area of the ablation electrode is achieved, and thermal damage is reduced.

The invention relates to the technical field of thermal therapy, in particular to an MRI imaging-based ultrasonic-assisted thermal therapy system, which is characterized in that the MRI imaging-based ultrasonic-assisted thermal therapy system comprises an MRI imaging module, a heat source module, an ultrasonic monitoring module and a control module, and the control module comprises a data fusion processing unit, a closed-loop power control unit and a mechanical arm trajectory planning unit; by means of multi-source fusion of MRI temperature mapping, ultrasonic real-time imaging and optical fiber temperature sensing, low-delay and high-precision tissue temperature and state monitoring is achieved, prediction-correction closed-loop control based on the Pennes equation is combined, the temperature control precision and the response speed are improved, a multi-focus and track type combined heating strategy is supported, the treatment time is greatly shortened, and the treatment effect is improved. According to the invention, the MRI compatible mechanical arm and the wearable fixing device are matched, high repeated positioning and flexible probe pose optimization are realized, the stability and safety of the treatment process are ensured through a multi-stage safety interlocking and redundancy monitoring mechanism, and efficiency, accuracy and clinical applicability are considered in thermal ablation treatment.

The invention discloses a radiofrequency ablation adjusting method and system based on multi-parameter fusion and real-time feedback, and belongs to the technical field of radiofrequency ablation. Through acquisition of various physiological signal data, single research on real-time tissue temperature and introduction of participation of an electric signal, an accurate cell water loss rate inversion value is obtained through inversion according to the electric signal; therefore, more accurate calculation data is provided, and a more accurate damage assessment result is ensured. Moreover, a preset tissue damage evaluation and prediction model is used for performing tissue damage prediction according to the cell water loss rate inversion value, complicated model updating and training are not needed, the enhanced damage evaluation efficiency of tissue damage is greatly improved, the real-time cell water loss rate is calculated through the real-time physiological signal data, the real-time cell water loss rate is used as a core damage criterion, and the accuracy of the enhanced damage evaluation of the tissue damage is improved. And performing damage assessment to generate a corresponding radiofrequency ablation real-time adjustment operation instruction according to a specific damage assessment result, and forming integrated control from parameter measurement to adjustment feedback.

The electrochemical sensor device is for introducing a needle electrode into the skin of a subject to contact the biological fluid or tissue of the subject and detecting a target analyte. The device has a movable part for inserting the needle electrode into the skin of the subject and a thermal energy sensor for specifying the temperature of the biological fluid or tissue.

A laser therapy device comprises a pulsed laser light source. Each triggering of tissue irradiation causes application of a first heating laser pulse of a first power and a first pulse duration and at least a second heating laser pulse of a second power and a second pulse duration to the tissue. Changes in volume resulting from the rising and the decreasing power gradient of the first laser pulse are detected. The therapy device, on the basis of the measured values relative to the change in volume and taking into consideration at least the predetermined rises of the power gradients of the first heating laser pulse, determines an estimated value for the temperature increase in the tissue during irradiation of the first heating laser pulse, and generates, from the estimated value, a command that causes adjustment of the second power and / or the second pulse duration of the second laser pulse.

Methods for increasing local blood circulation in soft tissue, treating musculoskeletal tissue, and treating soft tissue of a subject are described. Continuous, non-pulsed ultrasound energy can be applied to a target tissue region, such as with a wearable ultrasound transducer. The ultrasound energy can be delivered at an intensity suitable for sustained application for at least 60 minutes. A statistically significant increase in local blood circulation can be achieved within 10 minutes of initiating application, occurring before a statistically significant increase in tissue temperature. In some embodiments, a topical non-steroidal anti-inflammatory drug (NSAID) is applied to the target region during ultrasound application. In some embodiments, local blood circulation is monitored using laser Doppler flowmetry until a statistically significant increase in perfusion units is detected. The increase in local blood circulation can be effective to alleviate pain and accelerate recovery from a soft tissue injury.

The application provides an intraoperative real-time optical coherence imaging guided laser ablation treatment system, which comprises an optical guiding module, a laser treatment module and a real-time monitoring and feedback module; high-resolution three-dimensional information and blood vessel function information obtained by the optical coherence imaging guiding module are used to accurately segment the region of a tumor site, and the power and irradiation time of a radiation laser light source are accurately controlled according to the information; meanwhile, a temperature sensor monitors the tissue temperature at any time, and the system pauses laser diagnosis and treatment when the temperature exceeds the set threshold range, so that precise laser ablation treatment is realized; the application aims to overcome the problems that the current laser ablation treatment lacks real-time and accurate segmentation of tumor regions and lacks real-time monitoring and feedback of the tissues around the tumor during the operation, so that real-time and accurate laser ablation treatment of the tumor site during the operation is realized.

The invention discloses a water-cooling radiofrequency ablation needle, which relates to the technical field of medical appliances, and comprises an ablation needle body, an electrode tube is arranged at the front end of the ablation needle body, a radiofrequency electrode is arranged in the electrode tube, the end part of the radiofrequency electrode extends out of the electrode tube, the end part of the radiofrequency electrode is fixedly connected with a temperature probe, and the temperature probe is of a conical structure. The lower bottom face of the temperature probe abuts against the end face of the electrode tube. Through the arrangement, the temperature probe can be closer to a nervous tissue ablation part, the influence of an intermediate medium on temperature conduction is reduced, accurate detection of the temperature of an ablation area is achieved, the temperature probe is of a conical structure, the tip design facilitates the temperature probe to penetrate through the tissue more smoothly and make direct contact with target nervous tissue, and compared with other shapes, the temperature probe is more convenient to use. The conical structure can reduce the tissue resistance, and the real tissue temperature can be obtained faster and more accurately.

A device for studying the relation between tissue temperature and electrical impedance comprises a tissue placing container, a heating and heat preservation subsystem and a tissue temperature and electrical impedance testing subsystem, and has the characteristics that (1) various general instruments are not stacked any more, the subsystems are controlled in a centralized mode, accurate synchronization is facilitated, and (2) the degree of automation is high, temperature adjustment is convenient, and time and labor are saved. The whole temperature adjusting scheme and the whole testing scheme can be set at a computer end at one time, and manual control is not needed in the middle process; (3) the highest heating power is high and can reach 2kW or even higher, and rapid heating is supported; heat transfer modes are various, water bath heating comprises heat radiation and heat conduction modes, and the heat transfer efficiency is high; and (5) due to large specific heat of water, heat preservation and constant temperature of tissues are facilitated, measurement of low-frequency impedance is facilitated, and impedance spectrum measurement of frequencies below 100Hz is successfully covered.