2404results about "Electrocardiography" patented technology

The present invention relates to a system and method for providing adaptive digital therapy, enhancing the emotional well-being of users through the analysis and translation of expressive and physiological states. Aspects of the invention are directed to identifying the neuroplastic window via user inputs, with or without the aid of psychedelics. This invention is particularly suited for supporting psychoactive therapies involving compounds such as 5-HT2A agonists, dissociatives, and empathogens, as well as applications beyond psychoactive treatments. By utilizing multi-modal deep learning methods, the system captures a wide array of user inputs, including text, speech, vision, symbols, and brain waves, to form a dynamic user representation. This representation is then used to provide real-time, tailored generative communications informed by established psychological therapeutic frameworks. The invention features a closed-loop feedback system through an access module, enabling continuous data relay, patient response metric derivation, and transmission of emotional optimization communications. The system also introduces novel communication methods, including symbolic language input, to articulate complex experiences and extends its capabilities to include natural emotional states, broadening its therapeutic applicability.

Apparatus and methods are described including placing, into a subject's body, a blood-pump tube, with an impeller disposed within the blood-pump tube. At least one blood-pressure-measurement element extends to at least an outer surface of the blood-pump tube, such that the distal end of the blood-pressure-measurement element is in direct fluid communication with a bloodstream of the subject outside the blood-pump tube at a location that is proximal to blood-inlet opening(s) defined by the blood-pump tube. Blood is pumped through the blood-pump tube, using the impeller. Pressure of the bloodstream of the subject outside the blood-pump tube is measured by measuring blood pressure at the distal end of the left-ventricular blood-pressure-measurement element. Other applications are also described.

The invention relates to the technical field of neural rehabilitation training, and discloses a neural feedback rehabilitation training method and system. According to the method, electroencephalogram, near-infrared, myoelectricity and heart rate variability signals are acquired based on a multi-modal nerve-physiological signal acquisition device, and a nerve-physiological signal sequence is generated and input into a fusion processing system. And carrying out denoising, artifact removal and feature extraction on the data sequence to generate standardized feature data. And based on the standardized data, identifying the neural state of the user by utilizing a graph neural network, and generating personalized neural state trend data by adopting an attention mechanism in combination with historical data. Based on trend data and a training target, reinforcement learning is adopted to generate a personalized training strategy, training is implemented through an immersive interaction system, user behaviors and neural feedback are recorded, the training strategy is dynamically adjusted and uploaded to a cloud end, and a cloud-side collaborative optimization neural state model and algorithm are adopted, so that the intelligence and accuracy of rehabilitation training are improved.

The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.

Apparatus and methods are described including a ventricular assist device that includes a tube configured to traverse a subject's aortic valve. The tube defines a generally-cylindrical central portion, and a proximal conical portion that narrows from a proximal end of the central portion to a proximal end of the tube. The tube defines one or more blood inlet openings in a vicinity of a distal end of the tube, and one or more blood outlet openings that extend axially from the central portion of the tube at least partially into the proximal conical portion of the tube. A blood pump pumps blood into the tube from the subject's left ventricle through the one or more blood inlet openings, and from the tube into the aorta through the one or more blood outlet openings. Other applications are also described.

The invention relates to a method for determining at least a flow velocity or a fluid volume flow (5) of a fluid flowing through an implanted vascular support system (1), comprising the following steps: a) carrying out a pulsed Doppler measurement by means of an ultrasonic sensor (2) of the support system (1), b) evaluating a measurement result from step a), which has a possible ambiguity, c) providing at least one operating parameter of a flow machine (3) of the support system (1), d) determining at least the flow velocity or the fluid volume flow (5) using the measurement result evaluated in step b), wherein the possible ambiguity of the measurement result is corrected using the operating parameter.

A device and method for delivering a fluid as an ejected stream of droplets during inhalation uses inertial filtering to cause a first plurality of droplet particles generated by an ejector mechanism to pass through an airflow exit while a second plurality of droplet particles having a greater mass mean aerodynamic diameter than the first plurality of droplet particles fails to pass through the airflow exit.

The invention concerns a control device for controlling a blood flow of an intravascular blood pump for percutaneous insertion into a patient's blood vessel, the blood pump comprising a pump unit with a drive unit for driving the pump unit and configured to convey blood from a blood flow inlet towards a blood flow outlet, wherein the control device is configured to operate the blood pump in a selectable zero-flow control mode, wherein a blood flow command signal is selected, and the control device comprises a first controller and a second controller, wherein the first controller is configured to control the blood flow by adjusting a speed command signal for the drive unit, and the second controller is configured to control a drive speed of the drive unit.

Systems and methods are provided herein for treating a patient in cardiogenic shock. An intravascular heart pump system is inserted into vasculature of the patient. The heart pump system has a cannula, pump outlet, pump inlet, and rotor. The heart pump system is positioned within the patient such that the cannula extends across the patient's aortic valve, the pump inlet is located within the patient's left ventricle, and the pump outlet is located within the patient's aorta. Data related to time-varying parameters of the heart pump system is acquired from the heart pump system. A plurality of features are extracted from the data. A probability of survival of the patient is determined based on the plurality of features and using a prediction model. The heart pump system is operated to treat the patient.

The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters / signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and / or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.

Systems and methods for determining the positioning of intracardiac devices, such as intracardiac blood pump assemblies, using electrical sensors configured to sense electrical potential as it propagates through the heart. In one example, the present technology provides an intracardiac device with one or more electrical sensors mounted thereon, and a controller configured to determine the absolute or relative location of the intracardiac device based on the timing, shape, and / or amplitude of the electrical signals received from the one or more sensors.

The invention provides an expectoration auxiliary control method and device. The method comprises the steps that audio signals of breathing sounds and cough sounds at multiple positions of the chest of a patient are collected through an audio sensor array, and a standardized audio feature data set is obtained through noise reduction, segmentation and feature extraction; a dynamic weighted graph model is constructed, and a random edge sampling algorithm and a parallel batch processing dynamic algorithm are combined to analyze and obtain a sputum viscosity index and a sputum distribution position map; based on the result, mapping the vibration parameter space into an unweighted disk diagram, and obtaining a personalized vibration treatment scheme by using a shortest path algorithm; in combination with the real-time breathing cycle of the patient, working parameters of the sound wave vibrator and the negative pressure suction device are synchronously controlled, and a coordinated and consistent multi-mode treatment execution instruction is obtained; and collecting real-time feedback data in treatment, and dynamically adjusting working parameters through reinforcement learning to obtain an optimized expectoration adjuvant therapy scheme. Intelligent adjustment can be achieved based on the real-time breathing state and sputum characteristics of the patient, the expectoration efficiency is improved, and discomfort of the patient is reduced.

Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.

Embodiments disclosed herein are directed to a multi-function adapter system for placing a distal tip of a catheter at a target location. The system is configured to maintain one or more electrical communication pathways with the catheter distal tip during a placement procedure. Two or more electrical pathways can be cross-referenced to determine accuracy. The electrical pathways can include a clip and first tether that provides a versatile electrical pathway in that the clip can be selectively coupled with either a saline column, stylet, guidewire, or needle. A flushing adapter can include a second tether formed integrally therewith and provide a second electrical pathway with a saline column. The stylet or guidewire can be fixedly coupled with the flushing adapter and can provide a second electrical pathway with the second tether. These electrical pathways can provide a fail-safe system to ensure electrical communication with the distal tip of the catheter.

A blood pump system includes a catheter, a pump housing disposed distal of a distal end of the catheter, a rotor positioned at least partially in the pump housing, a controller, and an electrode coupled a distal region of the blood pump. The electrode can be used to sense electrocardiogram (EKG) signals and transmit the signals to a controller of the blood pump. The operation of the blood pump can be adjusted based on the EKG signal and on cardiac parameters derived from the EKG signal. Further, the controller can determine a need for defibrillation or pacing of the patient's heart based on the signal and can administer treatment with electrical shocks to the heart via the electrode coupled to the blood pump. The use of an electrode with a blood pump already in place in the heart allows for more efficient and safer treatment of serious cardiac conditions.

Disclosed is a system for providing a sleep healthcare service using brainwave entrainment and autonomous nervous system control, and the system including: a user terminal configured to set a bedtime and a wake-up time, at the bedtime, output a sleep-inducing breathing method for enhancing the parasympathetic nervous system, while emitting light of non-melatonin-suppressing wavelengths, and at the wake-up time, insert and output an Alpha-Band or Beta-Band flicker for brainwave synchronization of alpha or beta waves, and output blue light to induce arousal; and a sleep healthcare server.

Systems and methods for controlling an implantable pump are provided. For example, the exemplary controller for controlling the implantable pump may only rely on the actuator's current measurement. The controller is robust to pressure and flow changes inside the pump head, and allows fast change of pump's operation point. For example, the controller includes, a two stage, nonlinear position observer module based on a reduced order model of the electromagnetic actuator. The controller includes an algorithm that estimates the position of the moving component of the implantable pump based on the actuator's current measurement and adjusts operation of the pump accordingly. Alternatively, the controller may rely on position measurements and / or velocity estimations.

The invention discloses a self-adaptive music synthesis sleep aiding method and system based on physiological feedback. The method comprises the following steps: acquiring physiological data of a user; preprocessing the physiological data; evaluating the sleep state of the user based on the preprocessed physiological data; defining a music parameter space according to the sleep state; optimizing music parameters based on the sleep state and the music parameter space; generating and playing music according to the optimized music parameters; while music is played, physiological reactions of the user are continuously monitored, music parameters are adjusted in real time based on the physiological reactions, and feedback circulation is formed; analyzing a long-term sleep pattern of the user based on the data obtained in the feedback loop; according to the long-term sleep mode, updating a music parameter space and an optimization strategy; security monitoring is executed, and intervention is carried out when an abnormal condition is detected; according to the invention, a plurality of key indexes such as sleep time, deep sleep proportion, sleep quality and the like are obviously improved.

The present disclosure describes systems, devices, and methods of benefiting a cognitive state or function of a brain of a subject. The systems can include a portable system comprising a single headset device to be worn by a subject, comprising a pair of glasses configured to provide a visual stimulus to the subject, and a pair of supra-aural headphones configured to provide an auditory stimulus to the subject.

Embodiments are directed to in-bed haptic systems including a pneumatic pad configured for placement between a user and a bed. The pneumatic pad can include an array of actuation cells, where each actuation cell in the array of actuation cells is configured to actuate in response to fluid being introduced into the actuation cell. The system can include an input device that includes a touch sensitive display and is configured to display a set of haptic sequences that can be applied to the array of actuation cells in a user interface of the input device and receive an input at the touch sensitive display of a selected haptic sequence. The system can include a control system that receives an indication of the selected haptic sequence and actuates actuation cells of the array of actuation cells using the selected haptic sequence and the pressure measurements.

The invention discloses an intelligent infusion monitoring management system, and relates to the technical field of medical equipment, and the system comprises the steps: collecting patient data, synchronizing the patient data to a central monitoring system through a block chain technology, and generating a personalized infusion scheme; based on a personalized infusion scheme, a medical worker uses a mobile device to carry out identity verification on a patient and obtain medicine information, and a voice assistant function is integrated; the monitoring module is responsible for monitoring vital signs of a patient and the temperature of a ward by using wearable equipment and a temperature sensor, and adjusting a personalized infusion scheme and liquid temperature according to the vital signs and the temperature of the ward; the risk value prediction module is responsible for predicting risk values of blockage and leakage according to the adjusted personalized infusion scheme and the liquid temperature and setting a graded alarm mechanism; patients and family members receive the infusion progress through the intelligent infusion monitor. According to the invention, the block chain technology and the advanced artificial intelligence algorithm are integrated, so that the health data and medicine information of the patient can be efficiently managed and analyzed.

Systems and methods for generating nitric oxide are disclosed. A nitric oxide (NO) generation system includes at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas; and a controller configured to regulate the amount of nitric oxide in the product gas produced by the at least one pair of electrodes by utilizing duty cycle values of plasma pulses selected from a plurality of discrete duty cycles to produce a target rate of NO production based on an average of discrete production rates associated with each of the plurality of discrete duty cycles.

The invention relates to a method for determining at least a flow velocity or a fluid volume flow of a fluid flowing through an implanted vascular support system, comprising the following steps: a) carrying out a pulsed Doppler measurement by means of an ultrasonic sensor of the support system, b) evaluating a measurement result from step a), which has a possible ambiguity, c) providing at least one operating parameter of a flow machine of the support system, d) determining at least the flow velocity or the fluid volume flow using the measurement result evaluated in step b), wherein the possible ambiguity of the measurement result is corrected using the operating parameter.

An anesthetic equipment storage and waste air management module configured to housing electronic and electromechanical surgical equipment including a system to measure and record administration of one or more IV medications or fluids for IV administration. The module can include a housing having a lower section and a tower-like upper section, wherein the lower section is configured to house unrelated waste heat-producing electronic and electromechanical surgical equipment. The module can also include a cowling that substantially confines waste heat generated by the unrelated waste heat-producing electronic and electromechanical surgical equipment, and can include a system for measuring and recording the administration of the one or more IV medications and fluids.

The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to method of sleep diagnosis and treatment.

A catheter configured to guide and support a balloon catheter for use in and around a pulmonary vein and its ostium, has an elongated shaft and a distal assembly, the elongated shaft including a proximal portion with a first flexibility and a distal portion including a second flexibility greater than the first flexibility, the distal assembly including an elbow portion and a generally circular portion generally transverse to the longitudinal axis, the generally circular portion including a third flexibility greater than the second flexibility. Single axis location sensors and sensing ring electrodes are carried on the generally circular portion.

The invention relates to a ventilation tube (1) for ventilating a patient, comprising a tube (2) surrounding an air channel (25) with a tube wall (3) for insertion into a throat or trachea of the patient, a cuff (4, 15) with an air volume (6) circulating in the circumferential direction of the tube wall (3), and a pump line (5) running in the axial direction of the tube (2) for establishing a flow connection between the air volume (6) of the cuff (4, 15) and a pump device (7). In order to be able to detect conditions relating in particular to the breathing or ventilation of the patient with high quality, it is proposed that the ventilation tube (1) have an acoustic sensor (8, 16) arranged in the air volume (6) on the tube wall (3) or in a partial region of the cuff (4, 15) adjacent to the air channel (25).

A system and method to configure a rule set used in connection with a medical monitoring system for monitoring patients and patient care equipment, especially medication delivery pumps, based on a variety of conditions and parameters associated with monitored biometric information and equipment information and for providing user-defined responses to those conditions and parameters.

An electronically actuated droplet delivery device with a mouthpiece for inhaling fluid droplets includes an ejector mechanism having an electronic actuator operably coupled to an aperture plate. A fluid reservoir provided fluid to the ejector mechanism through a surface tension plate that increases contact between the fluid from the fluid reservoir and the aperture plate.

The present embodiments provide compounds of Formula I, compositions of the compounds, and methods for treating diseases such as cancer.