335 results about "Radiation therapy" patented technology

Disclosed herein are methods and systems to evaluate cost values for different radiotherapy treatment plans using external AI models. A method comprises presenting a user interface providing an interaction interface between a plurality of medical professionals communicating regarding a radiation therapy treatment of a patient during a tumor board meeting or a radiotherapy treatment planning process; receiving, from the interaction interface, a first input comprising a first patient attribute of the patient and a second input corresponding to the radiation therapy treatment of the patient; executing a machine learning language processing model using the first input and the second input to predict a task associated with generating a treatment plan for the patient; receiving, from the interaction interface, a third input; and when the third input does not correspond to the predicted task, presenting an indication of the predicted task.

Described herein are methods for monitoring the radiation delivery during a radiotherapy delivery session and providing a graphical representation of radiation delivery to an operator (e.g., a clinician, a medical physicist, a radiation therapy technologist). The graphics are updated in real-time, as radiation data is collected by the radiotherapy system, and in some variations, can be updated every 15 minutes or less. A variety of graphical representations (“graphics”) can be used to indicate the status of radiation delivery relative to the planned radiation delivery. Methods optionally include calculating a range of acceptable metric values, generating graphics that represent the range of acceptable metrics values, and generating a graphic that depicts the real-time values of those metrics overlaid with the range of acceptable metrics values.

Provided herein are methods for promoting or inducing hematopoietic regeneration, or preventing or treating hematopoietic deficiencies, or treating or ameliorating aplastic anemia induced especially by a chemotherapy, or a radiation therapy, comprising administering an effective amount of an adrenoreceptor agonist, especially a selective β2 adrenoreceptor agonist or a selective β3 adrenoreceptor agonist or a nonspecific β adrenoreceptor agonist.

The utility model belongs to the technical field of positioning devices, and particularly relates to a tumor radiotherapy positioning device which comprises a treatment bed, a first adjusting sliding rail and a second adjusting sliding rail are installed on the side face of the treatment bed, a first sliding block and a second sliding block are installed in the first adjusting sliding rail and the second adjusting sliding rail respectively in a sliding mode, and a supporting arm is installed on the side face of the first sliding block. A first electric telescopic rod is installed at the top of the supporting arm, a rotating adjusting seat is installed at the top of the first electric telescopic rod, a second motor is installed on the side face of the rotating adjusting seat, a rotating shaft is rotatably installed on the other side of the rotating adjusting seat, and an output shaft of the second motor is connected with the rotating shaft; the device can be used for comprehensively and uniformly fixing the waist of a patient with high fitting degree, automatically adapts to the waist body curve of the patient, has the function of adjusting according to the leg body types of the patient, can be conveniently adjusted according to the patients with different body types, and ensures the body position fixing stability of the patient.

The invention provides an aurone compound and medical application thereof, and relates to an aurone compound and application thereof in preparation of drugs for preventing and treating myelosuppression or blood system diseases. The aurone compound provided by the invention can significantly improve the myelosuppression state caused by rusotinib and radiotherapy, can recover the generation of erythrocytes after mouse irradiation and use of rusotinib, and has a significant effect on the recovery of leukocytes, especially neutrophils and lymphocytes, of the irradiated mouse. The invention provides a new potential drug for treatment of myelosuppression or blood system diseases.

Apparatuses and methods for treating tumors. A method of treatment may include reducing the microvasculature of a region between a tumor and a lumen through or adjacent to the tumor (e.g., by administering radiation therapy targeting the tumor), isolating a segment of a lumen proximate to the tumor, and administering a dose of a chemotherapeutic agent to the segment.

The invention provides a radiotherapy control method and a related device. The radiotherapy control method comprises the following steps: acquiring a heart motion model corresponding to an object to be subjected to radiotherapy; determining a to-be-sketched image from the plurality of medical images, and determining a moment corresponding to the to-be-sketched image as a target treatment moment, so that an operator performs target region sketching on the to-be-sketched image to obtain a corresponding sketched image; based on a heart motion model, determining a target electrocardiogram wave band and a target optical marker ball position corresponding to the sketching image; and performing radiotherapy on the to-be-radiotherapy object based on the target treatment moment, and if the deviation between the electrocardiogram wave band acquired by the electrocardiograph in real time and the target electrocardiogram wave band is smaller than a first preset threshold value and the deviation between the optical marking ball position acquired by the optical positioning system in real time and the target optical marking ball position is smaller than a second preset threshold value, performing radiotherapy on the to-be-radiotherapy object according to the sketched image. Through the method, the accuracy of radiotherapy is ensured.

The invention relates to the technical field of medical data processing, in particular to a data processing system and method applied to radiotherapy, and the system comprises a data collection and processing module, a data synchronous mapping module, a data cleaning and labeling module, a data analysis and optimization module and a data visualization module. Wherein; the data acquisition and processing module is used for acquiring multi-source data from different devices; the data synchronous mapping module is used for carrying out real-time synchronization and spatial alignment on data from different sources; the data cleaning and labeling module is used for performing anomaly detection, cleaning and labeling on the data of the data synchronous mapping module; and the data analysis and optimization module is used for identifying a potential association relationship between the data and optimizing a radiotherapy scheme. According to the method, standardization, synchronization and cleaning of the multi-source heterogeneous data are realized, and the treatment scheme is optimized by adopting the integrated learning and genetic algorithm, so that the data consistency and accuracy are remarkably improved, and individuation and precision of radiotherapy are promoted.

The present disclosure provides anti-ULBP2 antibodies or antigen binding fragments thereof, including bispecific. The antibodies are administered in combination with a chemotherapy agent, a radiation therapy, and / or an immune checkpoint inhibitor for treatment of basal squamous cancer. The present disclosure also relates to methods and kits for detecting a predisposition to, determining the risk of, and guiding therapy for ULBP2 related disorders.

Example methods and systems for template generation and target structure tracking are described. In one example, a computer system may obtain (a) planning image data that is associated with a target structure of a patient requiring radiation therapy, or (b) transformed image data that is generated based on the planning image data. Based on the planning image data and / or the transformed image data, the computer system may generate first material property data that represents a particular material property associated with the target structure. Based on the first material property data, the computer system may generate a template that represents the particular material property. The template may be generated to be matchable against second material property data that also represents the particular material property for tracking the target structure during a treatment phase.

A method for cancer diagnosis and treatment. In particular, in identifying associations between biomedical markers which is indicative of having a diagnostic, prognostic or predictive value for a medical condition, in particular nasopharyngeal cancer (NPC) metastasis after radiation therapy. The biomedical marker or group of biomedical markers associated with a high likelihood of responsiveness of a subject to a cancer therapy, preferably radiation therapy, wherein said biomedical marker or group of biomedical markers comprises at least 1, 2, 3, 4, or all markers selected from CXCR6, ASPHD2, DDX39B and AGAP9. Furthermore, an assay for detecting, diagnosing, graduating, monitoring or prognosticating a medical condition, or for detecting, diagnosing, monitoring or prognosticating the responsiveness of a subject to a therapy against said medical condition, in particular nasopharyngeal cancer, is provided, as well as a corresponding method for classifying a subject and a medical decision support system.

The present invention relates to the field of medical positioning technology, and in particular to a radiotherapy positioning device for tumor radiotherapy, comprising a detection bed, a fixing component, a mounting component, and an air-drying component, characterized in that the detection bed, the fixing component, the mounting component, and the air-drying component are all arranged on the upper side of the detection bed, the fixing component is used to clamp the heat shrink film, and the mounting component is used to fix the fixing component on the upper side of the detection bed. The present invention prevents the outer sleeve rod from moving up and down by the protruding part of the limiting ball inside the groove, thereby fixing the outer sleeve rod inside the fixing groove, thereby achieving the function of fixing the upper and lower splints on the top of the detection bed, the upper and lower splints are connected by sliding bars and sliding grooves, and can be fine-tuned in multiple directions, and by adjusting the sliding bars and sliding grooves, the required distance and angle can be formed between the upper and lower splints, thereby ensuring that the heat shrink film fits tightly to the specific part of the patient's body.

A microcapsule containing vitamin C and nitrate, said capsule comprising a wall material and a core material encapsulated in the wall material. The wall material comprises pectin and sodium carboxymethyl cellulose, and the core material comprises vitamin C, nitrate, and chitosan. The raw materials of the microcapsule comprise, in parts by weight: pectin 0.7-1.2 parts by weight, sodium carboxymethyl cellulose 0.7-1.2 parts by weight, chitosan 1 part by weight, and vitamin C and nitrate in a total amount of 0.3-1.2 parts by weight, the molar ratio of vitamin C to nitrate ions being 1:1-1:5. A use of the microcapsule in the preparation of a drug for preventing and / or treating damage to the salivary glands caused by radiation therapy, in particular a use in the preparation of a drug for preventing and / or treating damage to the salivary glands caused by radiation therapy for nasopharyngeal carcinoma.

A method and an apparatus for determining information regarding the location of energy deposition of an ion beam, in particular a proton beam, in an absorptive medium, such as in the tissue of a patient undergoing radiation therapy.

The invention relates to the technical field of tumor radiotherapy, in particular to an auxiliary imaging device for tumor radiotherapy. The invention provides an auxiliary imaging device for tumor radiotherapy, which comprises a mounting plate, a supporting seat, tumor emission therapy equipment, a therapy bed, a positioning mechanism and a control mechanism, the tumor emission therapy equipment is mounted on the right side of the mounting plate, the supporting seat is connected to the left side of the mounting plate, and the therapy bed is mounted on the upper part of the supporting seat; the upper side of the treatment bed is provided with a positioning mechanism and a control mechanism. Through cooperative use of the small air pump and the air bag, the head and body contours of a patient can be tightly attached, the stability and the static performance of the patient in the whole treatment process are ensured, imaging artifacts caused by slight movement are reduced through high-precision fixation, and the image quality and the resolution ratio are improved.

Thereto a method and a system for planning radiation therapy are provided, as well as an arrangement for radiation therapy planning and a computer program product for carrying out the method. For planning the radiation therapy, the following steps are performed. Patient data of a subject to be treated is received as well as image data of the subject to be treated. The image data comprises anatomical image data of one or more organs at risk associated with the functioning of the immune system. Next, the patient 122 data and the image data are processed to obtain a risk score for the one or more organs at risk associated with the functioning of the immune system. The risk score is indicative of the risk of hematologic toxicity in the subject to be treated in response to the radiation therapy. Then the radiation therapy treatment is planned using the obtained risk score.

A protection device for tumor radiotherapy, characterized in that it comprises two symmetrically arranged mounting rails (1), a slider (9), a protection main plate (11) and a protection sub-plate (13); each of the mounting rails (1) is provided with a folding seat (4) along its extending direction; the folding seat (4) is provided with a foldable connecting rod (5); the other end of the connecting rod (5) is provided with a C-shaped clamping head (6); a threaded rod (7) with a threaded connection is arranged on the C-shaped clamping head (6); the threaded rod (7) passes through one side of the open end of the C-shaped clamping head (6); the other end of the threaded rod (7) is provided with a clamping block (8); each mounting rail (1) is provided with a slide track No.1 (3); Electric telescopic rods (10) are provided at the four corners of the underside of the protective main plate (11), and a slider (9) is provided at the lower end of each of the electric telescopic rods (10); an opening portion (12) is provided which extends longitudinally through the main body of the protective main plate (11); the protective main plate (11) is each provided with a No. 2 slideway (15) on the left and right sides of the opening portion (12); a plurality of evenly distributed protective sub-plates (13) are provided in the No. 2 slideway (15); each of the protective sub-plates (13) can respectively perform a linear reciprocating movement along the extending direction of the No. 2 slideway (15).

The invention concerns compositions and a method for treating or delaying the onset, progression, or relapse of a cancer in a subject, the method comprising administering, optionally with radiation therapy, an inhibitor of: (a) DNA-Dependent Protein Kinase catalytic subunit, and an inhibitor of Poly-ADP Ribose Polymerase, wherein the cancer has a histone H3.3 mutation or is a homologous recombination-defective (HR-defective) cancer; or (b) wild-type isocitrate dehydrogenase, wherein the IDH inhibitor is administered in an effective amount to decrease wild-type IDH activity in cells of the cancer, and wherein the cancer carries a histone H3.3 K27M mutation, and / or the cancer has low DNA methylation and / or low histone methylation; or (c) histone acetyltransferase, wherein the cancer carries a histone H3.3 K27M mutation, and / or high histone acetylation; or (d) histone deacetylase, wherein the cancer carries a histone H3.3 K27M mutation, and / or has high histone acetylation; or (e) any combination thereof.

In various embodiments, a method of radiation therapy may include loading a planning image of a target within a human body. Furthermore, a position of the target may be monitored. An occurrence of substantial alignment between the position of the target and the position of the target in the planning image may be calculated. Furthermore, after the calculation, a radiation beam may be triggered to deliver a dose to the target within a brief period of time (e.g., less than one second).

The invention relates to the field of orthopedic appliances for bone or joint non-surgical treatment and the field of electrotherapy, magnetic therapy and radiation therapy, in particular to a postpartum infrared rehabilitation treatment device which comprises a treatment bed, a pelvis containing groove is formed in the treatment bed, an infrared heater is arranged at the bottom of the pelvis containing groove, and a transparent bottom plate is arranged at the bottom of the pelvis containing groove. A mounting base is arranged at the tail of the treatment bed, two fixing plates are slidably arranged on the mounting base, a synchronous driving mechanism is arranged in the mounting base and used for driving the two fixing plates to be synchronously separated or synchronously drawn close, connecting plates are slidably arranged on the fixing plates, bandages are arranged on the connecting plates, one ends of the bandages are fixedly connected with the connecting plates, and the other ends of the bandages are fixedly connected with the connecting plates. And the other end of the bandage is detachably connected with the connecting plate. The problem that in the prior art, the whole repairing process is driven by two legs of a patient, and labor is consumed is solved.

The present invention relates to MSLN-specific binding constructs comprising a designed ankyrin repeat domain with binding specificity for MSLN and a chelator capable of bonding to a radionuclide, as well as to such MSLN-specific binding constructs comprising a half-life extending moiety with binding specificity for serum albumin. The invention further relates to methods of producing such radio-labelled MSLN-specific binding constructs, pharmaceutical compositions comprising such constructs, and the use of such constructs or pharmaceutical compositions in methods for treating, imaging or diagnosing diseases, such as cancer.

A linear accelerator for a radiation therapy system includes a plurality of cavities aligned along a length of the linac and a channel extending between adjacent cavities of the plurality of cavities. The plurality of cavities include a first material and the channel includes a second material different from the first material.

A prostate-specific membrane antigen (PSMA)-targeting conjugate having a phosphonate backbone, which is used for tumor detection after chelation of a diagnostic nuclide and is used for radiation therapy after being combined with a treatment-type nuclide. A conjugate nuclide chelation part is replaced with a fluorescent probe or a cytotoxic drug so that the PSMA-targeting conjugate can then be used for diagnosis and treatment of diseases.

The invention provides a dose adjustment mechanism, and the subject of the invention is to reduce the influence of radiation in the dose adjustment mechanism of a radiation therapy device and suppress the occurrence of faults. The dose adjustment mechanism is characterized in that the dose adjustment mechanism (40) is provided with: an actuator (42) that is disposed apart from the radiation axis of the radiation therapy device (10) that irradiates radiation; and a grader (33) as an interference element that is moved in the vertical direction with respect to the radiation axis by the operation of an actuator (42) and that can switch between a state in which the grader is disposed on the radiation axis and a state in which the grader is not disposed on the radiation axis, the operation axis of the actuator (42) not intersecting the radiation axis.

The utility model belongs to the field of tumor radiotherapy racks, particularly relates to a tumor radiotherapy rack, and aims to solve the problems that in the prior art, although radiation protection can be realized through a protective cover in the use process, the protective cover cannot be expanded when radiation protection needs to be carried out on more parts, so that the protective range of the protective cover is limited, and the radiation protection effect is poor. In order to solve the problems that in the prior art, the protection range is small, according to the scheme, the nursing bed comprises a bed body and a protection cover used for protecting the part of a patient, universal wheels facilitating movement of the bed body are fixedly arranged at the four corners of the bottom of the bed body, and a headrest used for containing the head of the patient is placed on one side of the top of the bed body; supporting plates are fixedly arranged on the two sides of the bottom of the bed body, the bottom of the protective cover is slidably connected with the top of the bed body, the protective cover can be expanded through the expansion mechanism, the protective area of a patient is enlarged, medical articles such as treatment tools and drugs can be stored through the storage mechanism, and medical staff can take and use the medical articles conveniently in the treatment process.

A method of treating or preventing adverse outcomes associated with tissue plasminogen activator (tPA) administration, cerebral edema-related side effects, cerebral edema associated with radiation therapy, or migraine headaches by administering an effective amount of a SUR1-TRPM4 channel inhibitor, such as glyburide, and optionally the co-administration of a second therapeutically active agent, to a subject in need thereof. Adverse outcomes associated with tPA include cerebral hemorrhage, cerebral edema, physical impairment or death. The administration of the SUR1-TRPM4 channel inhibitors occurs prior to the radiation therapy, during the radiation therapy, after the radiation therapy, or combinations thereof. The SUR1-TRPM4 channel inhibitor is administered prior to surgical excision of a brain tumor, CAR-T therapy, or administration of flutarabine. Alternatively, or in addition, the SUR1-TRPM4 channel inhibitor is administered prior the onset of the cerebral edema-related side effects.

The invention provides a therapy apparatus and a radiation therapy apparatus capable of reducing the limitation on the movement range of a therapy table while suppressing the area of a therapy room. The movable door (70) slides to the left side in the transverse direction (D1) relative to the irradiation opening (55a) during the first sliding, and slides to the right side in the transverse direction (D1) relative to the irradiation opening (55a) during the second sliding. Namely, when the movable door (70) slides towards one side in the transverse direction (D1), the movable door (70) does not exist on the other side, and when the movable door (70) slides towards the other side in the transverse direction (D1), the movable door (70) does not exist on the one side. Therefore, when the treatment table (60) moves close to the wall part (103) (as shown in the states (a) and (b) in Figure 5), the movable door (70) slides to the side opposite to the treatment table (60), so that the space of the treatment table (60) can be ensured. At this time, even if the movable door (70) and the irradiation port (55a) are not excessively spaced apart, interference between the movable door (70) and the treatment table (60) can be suppressed.

A control unit (8) operates a magnetic resonance scanner (1) during the acquisition of magnetic resonance signals (S) during the examination of a patient (2) according to a number of protocols (P) and acquires the associated magnetic resonance signals (S). The control unit (8) first receives information (I) about the patient (2) from an oncology information system (11) and, depending on the information (I) retrieved from the oncology information system (11), automatically determines a number of protocols (P) with which the magnetic resonance scanner (1) is to be operated during the examination of the patient (2).