Micro-regional force application improves the control of the orthodontic movement of teeth in all six degrees of freedom. Micro regional force application utilizes an elastic repositioning appliance, a tooth positioner, a polymeric shell, or preprogrammed series of polymeric shells. The key components of the invention are the envelope of freedom, the force applicators, force couplers, counterpart coupling, vector modifiers, seating guides, decouplers, and forced balance points. Further, computerized finite element analysis determines the center of resistance and the center of rotation for each tooth to be moved. The present invention gently rotates and translates one or more teeth to a desired straight position within a treatment plan.