507 results about "Infection risk" patented technology

The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. As apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.

The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. An apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.

The present invention comprises methods and apparatuses that can provide measurement of glucose and other analytes with a variety of sensors without many of the performance-degrading problems of conventional approaches. An apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the removed blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system. A method according to the present invention comprises removing blood from a body, using an analyte sensor to measure an analyte in the removed blood, and infusing at least a portion of the removed blood back into the body. The use of a non-contact sensor with a closed system creates a system will minimal infection risk.

Novel orthopaedic bone screws / spinal pedicle screws and implants that include coatings to help promote a structurally stable interface between the implant and the patient's bone / tissue, and methods of coating such screws and implants are provided. The implants and methodologies described involve at least a coating that facilitates osseous integration, and additionally at least one coating that either reduces the risk of infection in immunologically suppressed patients and / or for utilization in patients who have infection, but who require stabilization, or coatings that permit the use of dissimilar metals and prevent galvanic corrosive reactions.

A laser system and method are described that will improve dental treatments in small animals, particularly in situations where periodontal disease has progressed to the advanced stages of periodontitis and when dental pulp is exposed by fracture or disease. A laser system is employed to achieve enhanced precision by selectively ablating affected tissue without damaging the collateral tissue. The laser system is also capable of sealing the tubules and eradicating bacteria within the periodontium to significantly reduce the risk of infection. Additional pre-treatment methods may be employed to further enhance the laser therapy.

The invention provides an ophthalmic, otic or nasal pharmaceutical composition, comprising levofloxacin or the pharmaceutical acceptable salts thereof and loteprednol etabonate, wherein the weight ratio of loteprednol etabonate to levofloxacin is 1:0.2-5. The use of ophthalmic, otic or nasal pharmaceutical composition of the invention in preparation of the medication for treatment of conjunctivitis, keratitis, blepharitis, dacrycystitis, hordeolum, corneal ulcer and ocular infection accompanied with ophthalmitis and even inflammation of the surrounding tissues, to prevent increase of bacterial infection risks and the tissue inflammation of the infected area after the ophthalmic surgeries or ocular injuries, to treat or alleviate the bacterial infection in combination with the tissue inflammation of the infected area, or to treat tympanitis, otitis externa and infective rhinitis.

An implantable medical device 10 such as a catheter with a controlled-release pharmacologically active ingredient for minimizing the risk of infection or other physiological afflictions associated with the implantation thereof. The device includes a base material and a controlled-release outer layer containing a bioactive material, for example, paclitaxel.

The invention relates to a dental implant and a preparation method of a bioactive antibacterial surface of the dental implant. The dental implant is characterized in that medical titanium or a titanium alloy is taken a substrate; a nanotube morphology is constructed on the surface of the substrate through anodic oxidation; the surface of the substrate is uniformly coated with a polydopamine bionic membrane layer formed by auto-polymerization; the dental implant with the bioactive antibacterial surface provided with in-situ grafted silver nanoparticles is obtained by means of the adsorption and reduction capabilities of a polydopamine surface for silver ions. By adopting the dental implant, a uniform discrete nanotube oxide layer is formed in situ on the surface of the titanium substrate to be taken as a storage carrier of a large quantity of antibacterial silver particles, and the bioactive antibacterial surface which grows in situ is prepared through the steps of surface dopamine auto-polymerization and in-situ soaking and reduction and the like, so that the implant surface has more durable antibacterial property, the hydrophilic performance and bioactivity of the surface are improved, the alkaline phosphatase activity of osteoblast on the implant surface is increased, the differentiation of the osteoblast is facilitated, the infection risk of the implant after the implant is implanted is lowered, and the implanting success rate is increased.

The invention discloses a serum-free culture medium for mesenchymal stem cells. The serum-free culture medium for the mesenchymal stem cells comprises the following ingredients: fibronectin at the final concentration of 25mu g / ml, basic fibroblast growth factors at the final concentration of 10ng / ml, human epidermal growth factors at the final concentration of 15ng / ml, recombinant human insulin at the final concentration of 1mg / ml, human transferrin at the final concentration of 0.55mg / ml, human blood albumin in a volume ratio of 5 percent, sodium selenite at the final concentration of 0.67mug / ml, L-carnitine at the final concentration of 5mM and resveratrol at the final concentration of 30mu M. When the mesenchymal stem cells are cultured by the serum-free culture medium for the mesenchymal stem cells, animal-derived serum is not contained, so infection risks can be controlled; the L-carnitine and the resveratrol which are added into the serum-free culture medium for the mesenchymalstem cells can effectively improve the growth state of the mesenchymal stem cells; and the growth speed of the mesenchymal stem cells is remarkably improved, and the biological characteristics of themesenchymal stem cells are kept unchanged.

A needle safety and protection device that automatically caps the used tip of a needle the instant the needle is withdrawn from the patient to protect the user against infection risks. A spiral type cut safety shield remains relaxed until the device comes in contact with the patient's skin. The safety shield attaches to the patent's skin through an adhesive component creating a tensile force once the needle is withdrawn, extending the safety disk out of its relaxed position. Under tension, the safety disk creates a cone around the needle, forming a protective shield for the needle, without any assistance by the user. The tip of the needle then engages a portion of the shield, which prevents the tip from being re-inserted into the skin of the patient or the user of the needle.

The invention relates to an intelligent sputum suction device, which comprises a sputum suction detection warning device, a sputum suction action operation arm, a center controller, a sputum suction tube clean replacing box, a sputum suction and collection device and a sputum suction tube, wherein the sputum suction detection warning device is used for detecting and judging whether the sputum suction is needed or not; the sputum suction action operation arm clamps, pulls and feeds the sputum suction tube, and is provided with a pressure sensor used for detecting the tube feeding resistance; a clean sputum suction tube and a waste sputum suction tube are placed in different regions in the sputum suction tube clean replacing box; a sputum collecting bottle is arranged in the sputum suction and collection device; an infrared ray detector is configured for analyzing sucked sputum; and a central controller receives various detection signals, controls the actions of forward pushing, backward retreating, rotating and the like of the sputum suction tube, and controls the starting and the stopping of the negative pressure pump. The intelligent sputum suction device has the advantages that the sputum suction operation can be effectively realized; the sputum suction position is not limited in the front section of an artificial airway; the deep sputum suction can be effectively realized; the condition of infection risk increase due to mutual pollution of the sputum of a patient and sputum suction equipment is effectively avoided; and the injury on the respiratory tract mucosa of the patient caused by sputum suction operation is reduced.

A method and composition for treating enteric pathogen infections in animals suffering from such infections or displaying diseases or conditions consistent with such infections or for preventing or reducing the likelihood of enteric pathogen infections in animals at risk for developing such infections.

A collagen-based bio-absorbable wound dressing which contains a linear polymer biguanide and / or a water-soluble salt thereof. The biguanide is preferably polyhexamethylene biguanide. The bio-absorbable wound dressing has a long residence time in the body, is extremely well tolerated and leads to rapid and uncomplicated wound healing with clearly reduced infection risk.

The present invention provides a combination of medicines for eyes or ears and nose, which comprises levofloxacin and loteprednol carbon ester; wherein, the weight ratio of the loteprednol carbon ester to the levofloxacin is between 1 to 0.2 and 1 to 5. The combination of medicine for eyes or ears and nose of the present invention is used for curing conjunctivitis, keratitis, blepharitis, dacryocystitis, hordeolum, corneal ulcer and eye infection with inflammation of eyes or even inflammation of tissue around eyes. The combination is also used for preventing bacterial infection risk after ophthalmology operation or eye injury and inflammation of the infected region, or the combination is used for curing or alleviating bacterial infection and tissue inflammation of the infected region after ophthalmology operation or eye injury, or cure tympanitis, otitis externa and infectious rhinitis.

The present invention provides methods of treatment and / or prevention of infections, for example, viral and bacterial infections, in individuals, wherein the method comprises administering a supraphysiological amount of mannose-binding lectin (MLB) and / or ficolin-MBL fusion protein to an individual afflicted with an infection or at risk of an infection, such as a bacterial or a viral infection. For example, methods for treatment and / or prevention of Ebola virus infection are provided.

The invention provides a fully-water soluble fertilizer and relates to a fertilizer. The fully-water soluble fertilizer consists of K2SO4, (NH4)2SO4, urea, monoammonium phosphate, fulvic acid potassium, zinc, boron, a plant growth regulator and naphthylacetic acid, and the mass percentage occupied by the components is shown as follows: 30-50 percent of K2SO4, 30-40 percent of (NH4)2SO4, 3-8 percent of urea, 5-15 percent of monoammonium phosphate, 10-30 percent of fulvic acid potassium, 1-3 percent of zinc, 1-3 percent of boron, 0.3-0.8 percent of plant growth regulator and 0.3-0.8 percent of naphthylacetic acid. The fully-water soluble fertilizer has the beneficial effects that the fully-water soluble fertilizer is formed by adopting high-quality imported N, O and K as main materials, adding trace elements, i.e. zinc and boron, mixing auxin DA-6, and refining and processing; the fully-water soluble fertilizer has the effects of cold resistance and drought resistance, enhances the photosynthesis of crops, is a necessary nutrient element for maintaining a chloroplast structure, has remarkable effect on paper plant growth metabolism and facilitates the growth and the development of the crops; the infection risk of cottons, wheat, melons and fruits, and other virus and diseases can be reduced; and the fully-water soluble fertilizer is the high-quality fertilizer for supplanting crop nutrition and has the characteristics of fast dissolution, full dissolution, yield increment, efficiency increment and the like.

Embodiments described herein relates to a platform for infection surveillance that can assist infection preventionists and antimicrobial stewardship teams with infection detection rules and dynamic alerts by aggregating and processing infection surveillance data with contextual healthcare data regarding a facility, organization, and so on. The platform can enable proactive prevention of infection risks by detecting risk patterns in the data and generating alerts.

A device is disclosed which couples the use of Trans Epithelial Nerve Stimulation with the administration of a therapeutic injection, such as an immunization, or tissue sampling procedure such as deriving a blood sample. By such an arrangement the discomfort associated with these procedures may be considerably reduced or eliminated, thereby improving compliance with a range of medical procedures. To date TENS has not been used in such an arrangement, rather development in TENS technology has been aimed at improving its efficacy. Similarly injection technology developments have been orientated around reducing cross infection risks and accidental injury to operator or patient.

The invention provides an umbilic clamping cutter, comprising a pushing and cutting rod, a mother clamp, an infant clamp and a clamp holder, wherein one end of the pushing and cutting rod is provided with a blade while the other end is a cartoon; one surface of the pushing and cutting rod is fixed with a pick matched with the infant clamp; and one end of the clamp holder is connected with the mother clamp and the infant clamp while an inwall chute at the other end thereof is matched with the pushing and cutting rod. As one end of the clamp holder is manufactured into a big opening, only one end of the clamp holder operates by fingers, the whole operation process can be seen clearly from the big opening; the umbilical cord is clamped by two clamps in advance so as to facilitate the blade to cut; when in operation, the pushing and cutting rod is driven by hands to cut the umbilical cord actively like an injector, thus having easy cut-off and good cutting effect, saving labor, and avoiding blood from sputtering, thereby ensuring physical and psychological health of medical care personnel. The umbilical cord is clamped at first and then the blade is moved to cut, so the length of the reserved umbilical head can be short so as to shorten the drying time thereof, accelerate drop of umbilical head and avoid infection risk induced by the overlong reserved umbilical head.

A fixing structure of bone screws and a connecting rod for a minimally invasive surgery contains: a rigid sleeve having a receiving space, two slots, and a through hole, the receiving space and the through hole being defined on two ends of the rigid sleeve, and the two slots being formed on two opposite sides of an outer wall of the rigid sleeve and communicate with the receiving space; a flexible column being circular and retained in the receiving space of the rigid sleeve. Thereby, a complete rigid limitation and partial flexible limitations generate between at least one bone screw, hence only a tiny opening is cut in the minimally invasive surgery to facilitate surgery recovery and to lower infection risk.

The invention discloses a community epidemic prevention management system linked with face recognition and temperature measurement access control. Master control module, the main control module is coupled with a registration module, a detection module, an alarm module, a data management module and a community management module; the registration module is used for real-name identity verification registration of community residents, the detection module is used for face recognition and temperature measurement of the community residents, and the community management module is used for community managers to master community epidemic situations at the first time and reasonably control communities at the first time according to the epidemic situations. According to the invention, the face recognition module and the body temperature detection module are arranged; according to the invention, residents can be identified and detected by themselves and can be used day and night, the work intensity of community workers is reduced, the infection risk is reduced, the alarm module is arranged to prompt and alarm the residents with abnormal body temperature, suspected cases can be screened out inadvance, and the infection probability of other people is greatly reduced.

The invention discloses a flexible microneedle drug delivery patch containing a separable drug capsule suitable for transdermal delivery of multiple drugs. The microneedle drug delivery patch has the advantages that pain level is low, infection risk is low and application is convenient. The microneedle drug delivery patch comprises the separable and replaceable drug capsule, a drug carrying end integrating a microneedle array with a microfluid flow passage network, a drug delivering end integrating the microneedle array with the microfluid flow passage network, and a sticky patch body allowing the microneedle drug delivery patch to be attached to skin, wherein the sticky patch body is made from a flexible polymer and is high in curvature and skin bonding property. In use, the drug delivery patch is attached to a joint of a user, the drug carrying end and the drug capsule of the drug delivery patch deform under the squeezing and stretching actions of the bent joint on the flexible microneedle drug delivery patch, so that a syringe needle at the drug carrying end pierces into the drug capsule and drugs are distributed to the drug delivering end through the microfluid flow passage network, and then drugs flow into the body through a passage formed on skin by a microneedle at the drug delivering end to finish drug delivery.

The invention discloses a puncture device causing less pain. The puncture device comprises a blood taking needle, a rod head, a rod body and a tail rod, wherein the rod head is fixed to the front end of the rod body; the tail rod is arranged at the back end of the rod body; an ejection assembly is arranged in the rod body; a needle seat is movably connected in the rod head; a handle rod of the blood taking needle is connected in the needle seat; the front end of an ejection rod in the ejection assembly is over against a carrier rod communicated with the back end of the needle seat. In the puncture device causing less pain having the structure, the ejection device is separated from the needle seat of the blood taking needle, thereby interrupting deviation shake caused by ejection of the ejection device in the transmission process of the needle seat, preventing the phenomenon of shake or deviation of the blood taking needle in a skin contact process, and reducing pain of a patient. Moreover, by improving an indicating sleeve and the tail rod, the infection risk of an operator is further lowered, the operation efficiency is increased, and the manufacturing cost is reduced.

The invention provides an epidemic situation propagation tracking method and system. The method is based on space-time big data and artificial intelligence technology, a research method which integrates new coronal pneumonia individual attack risk factors and a personal close contact dynamic relation network is adopted, and a more comprehensive personal infection risk assessment model is constructed. According to the method, the real-time data mining technology and the knowledge graph technology are combined, and the personnel space-time relation graph is constructed, so that dynamic management of close contact relations of infected persons and cross-department knowledge fusion can be realized. Meanwhile, an infectious disease model is applied to a dynamic personnel relation map with a local community structure and is combined with epidemiological investigation and research, and the personal close contact relation between individual attack risk factors and individuals is comprehensively considered, so that scientific, rapid, accurate and dynamic personal infection risk assessment and modeling prediction are realized; therefore, potential infected persons with high risk can be found as soon as possible, and the epidemic situation prevention and control management capability can be improved.

The invention relates to the therapeutic use of a second generation immunomodulatory oligonucleotide in combination with HIV-1 antigen or immunogen to enhance the ability to reduce the risk HIV infection and to control the progression of HIV infection to prevent AIDS Related Complex (ARC) and AIDS.

The invention discloses a monoclonal antibody of a blood coagulation factor IX. The antibody comprises a light chain and a heavy chain, wherein the variable region amino acid sequence of the light chain is represented by SEQ ID NO.3, and the variable region amino acid sequence of the heavy chain is represented by SEQ ID NO.4. The invention also discloses a preparation method of the antibody. The antibody can specifically identify the blood coagulation factor IX. The invention further discloses a method for purifying the blood coagulation factor IX from blood plasma through utilizing the antibody. The blood coagulation factor IX can be conveniently and efficiently purified from the blood plasma through utilizing the antibody, so the infection risks of the diseases comprising hepatitis A, the hepatitis B, AIDS and the like caused by the patient blood transfusion supplementation of the blood coagulation factor IX are reduced.

The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag—TiO2 coating shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and / or endoprothesis, especially where high infection risk exists.