70 results about "Intervention effect" patented technology

It is a Doppler velocimeter based on self-mixed intervention effect and belongs to laser measurement field, which comprises light source, measurement part and signal process three parts. The system light source uses double-frequency laser and locates a quarter of wave sheet in the system measurement part, that is system outer chamber, wherein, the light beam moves around in the outer chamber for once and makes the polarization direction turned into the original vertical direction. As to the velocimeter, when there is no Doppler frequency shift, the laser power spectrum has only one spectrum line; when there exists Doppler frequency shift, the power spectrum has two original spectrum lines and the differential value between the two spectrum lines relative beat frequency signals represents the velocity direction and the distance between the two spectrum lines is converted into velocity.

The invention relates to an identification method for a urine metabolism marker based on alzheimer disease. The identification method aims at solving the problem that a urine metabolism marker of existing alzheimer disease has not been clarified. The identification method for the urine metabolism marker based on alzheimer disease includes the specific steps that 1, alzheimer rat model is built and evaluated; 2, the intervention effect of Kaixin powder on building different-stage AD fat models is evaluated through the biomarker. The identification method is used for the field of metabolism marker identification.

The invention discloses a health management method based on a large data intelligent algorithm and system. The health management method comprises steps: based on evidence-based medicine, epidemiologyand crowd intervention data, a multi-layer cumulative logistic regression model is established, multi-dimensional individual health measurement indexes and a nutrition and health intervention scheme library are generated, an individual nutrition and health intervention scheme decision tree model is established by using the individual health measurement index information, and an individual nutrition and health intervention scheme is acquired. During the nutrition and health intervention scheme execution process, health assessment is carried out regularly and best intervention effects are achieved. The management system established based on the method is composed of three modules: a personal health information acquisition module, a calculation module and a display and supervision module. Through the health management method and the system, scientific, personalized and traceable health management solutions can be provided for residents.

The invention discloses an application of curcumin in the preparation of a thyroid carcinoma therapeutic agent, and belongs to the technical field of curcumin pharmaceutical application. Curcumin can kill thyroid carcinoma cells specifically and has little influence on normal thyroid cells. Curcumin can promote the apoptosis of thyroid carcinoma cells, initiate the digestion of poly adenosine diphosphate-ribose polymerase (PARP), and significantly inhibit the expression of anti-apoptotic protein Bcl-2; meanwhile, curcumin can also inhibit the secretion of thyroid carcinoma cell matrix metalloproteinase-9 and the adhesion to extracellular matrix. Above results show that curcumin has good intervention effect on various links of proliferation, migration, and adhesion of thyroid carcinoma cells, and is applicable to the preparation of medicaments for treating thyroid carcinoma.

The invention relates to a new application of oleic acid and glycerol 1-monooleate in the preparation of a kit for evaluating the intestinal lipid accumulation in a tested organism and its intervention effect, and a detection method of the oleic acid and the glycerol 1-monooleate. A reagent and the method are used to detect the content of the oleic acid and the glycerol 1-monooleate in the intestinal tissues of the tested organism. The invention further provides the method for detecting the content of the oleic acid and the glycerol 1-monooleate in the intestinal tissues of the tested organismthrough gas chromatography-mass spectrometry. The content can be used for evaluating the intestinal lipid accumulation and its intervention effect. The kit and the detection method have the characteristics of simplicity in operation, good reliability, fastness, high sensitivity, high specificity, and easiness in promotion.

The invention discloses a cognitive competence assessment intervention system for autistic children based on layer-by-layer generalization push logic. The system comprises a data acquisition module, a camera video permission request module, a cognitive competence assessment module, a cognitive competence intervention plan generation module, a cognitive competence intervention training module and a cognitive competence digital rehabilitation report module. According to the invention, no special equipment requirement is required, a family only needs to have an intelligent terminal device capable of surfing the Internet, the equipment cost is low, the intervention requirement on parents is very low, the autism children can carry out digital rehabilitation intervention training in a familiar environment, the intervention effect is greatly improved, and therefore, the system is a beneficial supplement for the autistic children with cognitive function defects to receive intervention training of professional rehabilitation therapists, and is particularly suitable for autistic children with cognitive function defects or families with limited energy of parents in areas with backward medical conditions and lack of professional rehabilitation therapists.

The invention relates to an optimal control method aiming at nuclear accident loss and emergency action cost, belonging to the field of nuclear hazard control. The optimal control method comprises the following steps of: (1) confirming a nuclear accident simulation range; (2) acquiring prediction results of wind filed and turbulent flow of the nuclear accident simulation range; (3) acquiring nuclear accident simulation range data observed by a meteorological observation network at the real time; (4) carrying out assimilation on the prediction results of the field wind and the turbulent flow in the step (2) and the acquired data observed by the meteorological observation network at the real time in the step (3); (5) carrying out diffusion simulation on nuclear accidents; (6) acquiring nuclear accident early-warning information; (7) formulating an optimal control scheme of the nuclear accident loss and the emergency action cost; and (8) providing the optimal control scheme of the nuclear accident loss and the emergency action cost for a commander to make decision. The invention improves the diffusion simulation precision, solves the contradiction between the accident emergency intervention effect and the action cost and improves the solving efficiency of the optimal control problem by more than two magnitude orders.

The invention discloses a medicine-food dual-purpose composition for reducing postprandial blood sugar (IGT state) and a preparation method, and belongs to the field of preparing food-therapy products, healthcare products and traditional Chinese medicines. The medicine-food dual-purpose composition is prepared from the following components in parts by weight: 12-25 parts of extract of leaf of narrow-leaved oleaster, 15-28 parts of mongolian dandelion herb extract, 9-16 parts of mulberry leaf extract, 5-9 parts of longstamen onion bulb extract and 35-50 parts of chicory herb extract. The preparation method of the composition comprises the following steps: performing low-temperature extracting, low-temperature concentration and low-temperature drying on the leaf of narrow-leaved oleaster, mongolian dandelion herb, the mulberry leaves, the longstamen onion bulb and the chicory herb, and then preparing the extracts into various oral preparations. According to the medicine-food dual-purpose composition for reducing postprandial blood sugar (IGT state) and the preparation method, the components are medicine-food dual-purpose species, so that the composition is safe and can be taken for a long time; the medicine-food dual-purpose composition can effectively reduce the postprandial blood sugar (IGT state), and is a safe and effective product for prediabetic-state patients; the medicine-food dual-purpose composition can also exert an intervention effect on the diabetic patients.

The present invention includes systems, devices, and methods relating to the monitoring of the functional maturation of biological interventions effecting cardiac pacing.

The invention relates to application of a ginsenoside Rb1 and Rd combination to preparation of a medicine for treating photoreceptor cell death related diseases. A mouse model suffering from retinal light damage is adopted to simulate the common key pathological links in the process of various degenerative retinal diseases so as to research the intervention effects of the ginsenoside Rb1 and Rd combination on the mouse model suffering from retinal light damage, and the results show that the medicinal combination can maintain the format of the retina outer nuclear layer, effectively prevent the retina outer nuclear layer from degenerative damage and thickness reduction, inhibit death of photoreceptor cells, block oxidative stress of retinal pigment epitheliums and photoreceptor cells, effectively inhibit retinal damage related immuno-inflammatory responses and remarkably improve the degenerative retinal diseases. Therefore, the ginsenoside Rb1 and Rd combination can be used for preparing the medicine for treating various degenerative retinal diseases including age-related macular degeneration, retinal pigment degeneration, Stargardt disease, cone-rod cell dystrophy, diabetic retinopathy and the like.

The invention discloses an intervention effect of a ginsenoside Rg1 on autoimmune encephalomyelitis mouse, belonging to the field of Chinese herbal medicine monomer intervening disease. The autoimmune encephalomyelitis (EAE) model of cord sheath oligodendrocyte glycoprotein peptide MOG35-55 immune C57BL / 6 mouse is an international accepted multiple sclerosis mouse animal model, establishing the model, and simultaneously inducing, using the ginsenoside Rg1 to intervene, through observing the impact of the ginsenoside Rg1 on the phenotype and the histopathology of the EAE model, obtaining that the ginsenoside Rg1 can significantly reduce the incidence of the autoimmune encephalomyelitis. Therefore, the ginsenoside Rg1 has a certain role in the intervention of multiple sclerosis. The ginsenoside Rg1 can significantly reduce the disease incidence of the multiple sclerosis animal model-EAE mice.

The invention provides an independent space-based intelligent psychological assessment and intervention system. The system comprises a psychological intervention cabin and a central database for realizing data interaction with the psychological intervention cabin, wherein the psychological intervention cabin comprises a shell, a data acquisition module, a data processing module and an intervention module; the data acquisition module is used for acquiring physiological and psychological data of a visitor; and the data processing module performs operation processing on the acquired data, establishes multi-dimensional state points of the visitor according to a mathematical model, matches the multi-dimensional state points with data in the central database, finds out an intervention procedure suitable for the visitor, and guides the intervention module to perform intervention. In the intervention process, the data acquisition module continuously acquires the physiological and psychological data of the visitor, and the data processing module forms new multi-dimensional state points according to the new data and performs re-matching to adjust the intervention procedure; and the process is repeated, so that the intervention procedure is continuously adjusted in the intervention process, an intervention scheme most suitable for the visitor is sought, and the best intervention effect is achieved.

The invention discloses a method for extracting ginkgo semen essential oil. On the basis of removing a germ by using an ultrasonic concussion-multistage cyclone separation technique, the ginkgo semenessential oil is obtained by adopting a supercritical CO2 extraction and molecular distillation integrated technology; the purposes of separating an impurity and enriching a functional substance are realized; a toxic component is decreased to an extremely low level, and the safe eating is ensured. The ginkgo semen essential oil extracted by using the extraction method provided by the invention hasunsaturated fatty acid accounting for more than 92% of total fatty acid and total flavone which is more than 0.10%, contains bilobalide, ginkgolide A, B and C, total terpene lactone which is more than 0.02%, xanthophyll, beta-carotene and alpha-carotene and carotenoid with a total amount more than 1 mg/100g. The functional substance has multiple biological functions of delaying senescence, lowering content of total cholesterol in blood, resisting oxidization, resisting a cancer, and the like, and has extremely good intervention effects on cardiovascular and cerebrovascular diseases and alleviating a neurodegenerative disease.

The invention discloses a breath guiding device and a breath guiding method. The breath guiding device comprises an ideal entropy feedback device, a life entropy corrector and a respiratory wave guidedevice, wherein the ideal entropy feedback device and the life entropy corrector are connected in series so as to form a self-excitation breath guide closed loop, and the ideal entropy feedback device and the respiratory wave guide device are used in combination so as to form a mutual excitation breath guide open link. According to the breath guiding method, the heart rate and respiratory rate signals of a human body are obtained through a remote sensing detection radar; and analysis is performed so as to obtain corrected entropies, and a signal feedback path is established. According to thebreath guiding device and the breath guiding method of the invention, self-excitation control is performed on the breath guiding device on the basis of the rule of corrected entropy minimization, so that intervention intensity can be learned and corrected, and therefore, an intervention effect can be improved, co-frequency guidance and resonance guidance are connected in series, and the co-frequency and resonance mutual excitation effect of a group can be optimized.

The present invention relates to new uses of an Ajuga ciliata Bunge extract, particularly to applications of the Ajuga ciliata Bunge extract in preparation of drugs for prevention and treatment of gynecological inflammatory diseases. According to the present invention, experimental results show that the gynecological inflammation treatment effects of the Ajuga ciliata Bunge extract on the two chronic pelvic inflammatory disease rat models caused by escherichia coli and phenol paste are verified, wherein the change of the blood rheology, the inflammatory factors and other indicators of the chronic pelvic inflammatory disease rat model caused by the phenol paste are observed after using the Ajuga ciliata Bunge extract, the change of the immunology indicator of the chronic pelvic inflammatory disease rat model caused by the escherichia coli is observed after using the Ajuga ciliata Bunge extract, and the intervention effects of the Ajuga ciliata Bunge extract on the uterus tissue inflammatory infiltration caused by chronic inflammations, tissue adhesion, and inflammatory mass caused by attachment hyperblastosis and the like are observed, such that the Ajuga ciliata Bunge extract provides the treatment effects on the long-term chronic inflammations and the attachment hyperblastosis caused by the long-term chronic inflammations.

The invention discloses a tool SYCE3 gene for the diagnosis or the treatment effect evaluation of damp heat type advanced colorectal cancer patients. The content of the expression product of the SYCE3 gene in the blood of a human subject is detected to judge whether the human subject suffers from the damp heat type advanced colorectal cancer or not or evaluate the medicine intervention effect of the damp heat type advanced colorectal cancer patients. The invention also discloses a kit for the diagnosis or the treatment effect evaluation of damp heat type advanced colorectal cancer patients based on the above research accomplishment. The kit can be used for detecting blood samples, belongs to noninvasive detection, and has the advantages of sensitive and fast detection effect, and facilitation of clinic promotion and use.

The invention discloses oligosaccharide with insulin resistance activity intervention effects and a preparation method thereof, and the preparation method comprises the following steps: Chinese yam degreasing, deproteinization, pigment removal, purification, enzymolysis and dialysis and refining, wherein the enzymolysis step is as follows: purified Chinese yam polysaccharide powder is dissolved bydistilled water, the pH value is adjusted, undecanol and petroleum ether are added, then polygalacturonase, beta-galactosidase, beta-mannase and beta-glucanase are sequentially added, ultrasonic-assisted enzymolysis, enzyme inactivation, cooling and centrifugation are carried out, and supernate is taken for later use. The preparation method disclosed by the invention has the beneficial effects that ultrasonic wave assistance is used, the polygalacturonase, beta-galactosidase, beta-mannase and beta-glucanase are sequentially utilized to carry out step-by-step enzymolysis on the Chinese yam polysaccharide, hydrophobic substances undecanol and petroleum ether are added, by cooperation with the cavitation effect of the ultrasonic wave, a complex bonding structure of the Chinese yam polysaccharide is fully digested, the enzymolysis efficiency is greatly improved, and the method has the advantages of being convenient to operate, high in efficiency and free of pollution.

The invention discloses a method for predicting a time sequence intervention effect. The method comprises the following steps: acquiring a data set; constructing a deep learning model; enabling two depth representations formed by the same input in the two recurrent neural network units to form a pair, and applying orthogonalization constraints to the pair; defining a total loss function, and minimizing the total loss function to realize training optimization of the model; training on the training set by adopting different hyper-parameter combinations, verifying the performance on the verification set, selecting the optimal hyper-parameter combination, and testing the deep learning model trained by adopting the optimal hyper-parameter on the test set to obtain a predicted intervention effect. According to the prediction method provided by the invention, related representations of intervention measures and intervention effects are respectively learned by utilizing two recurrent neural network units through a multi-task learning strategy, hybrid factors causing selection bias errors are eliminated through orthogonalization constraints, and finally, decoupling representations on a time sequence are obtained through training and are used for predicting the intervention effects of the time sequence.

The invention discloses a somatosensory game biofeedback rehabilitation method for children with autism. The method comprises the following steps: designing a somatosensory game scheme; wearing eye tracker equipment and electroencephalogram equipment and implementing intervention; collecting data; performign core experiment formula equation processing to obtain infantile autism child development intervention suggestions, and displaying the infantile autism child development intervention suggestions in a rehabilitation bracelet/mobile phone rehabilitation app to guide a patient to carry out biofeedback intervention training. Compared with the prior art, the method has the advantages that electroencephalogram and eye movement technologies are combined and introduced into a biofeedback technology, development changes and eye movement condition data of different brain regions of the autistic children are collected, dynamic and continuous monitoring of electroencephalogram and eye movementparameters of the autistic children is achieved, and the intervention effect is evaluated objectively and quantitatively. The morbidity of the autism tends to be high, and as a common type in childrendevelopment disorders, implementing scientific and efficient early intervention on the autism has important social significance and market value.

The invention discloses a pharmaceutical composition of amoxicillin and medical application of the pharmaceutical composition. The pharmaceutical composition of the amoxicillin comprises amoxicillin and a natural product compound (I) of a novel structure. When the amoxicillin and the compound (I) work independently, the myocardial fibrosis of a renovascular hypertension-model mouse can be intervened by virtue of an effect of decreasing the collagen concentration; when the amoxicillin and the compound (I) collectively work, the intervention effect is better; a drug for preventing the myocardial fibrosis of a renovascular hypertension patient can be developed, so that compared with the prior art, the pharmaceutical composition of the amoxicillin has remarkable substantive features and notable progress.

The invention provides a preparation method and application of deep sea water and fucoidin composite liquid. The composite liquid is prepared from deep sea water and fucoidin which are composited, wherein the hardness of the deep sea water is 1000 ppm, the molecular weight of the fucoidin is 270 KD, and the fucoidin is derived from brown alga sargassum pallidum. Experiments show that compared witha composited single component, the composite liquid disclosed by the invention can more obviously inhibit glycogen output quantity increment and lipid accumulation caused by high-concentration glucose induction, further can activate PI3K/Akt and AMPK signal channels to a greater extent and can improve insulin resistance; thus, the composite liquid has a more obvious intervention effect on metabolic diseases. The preparation method disclosed by the invention can provide theoretical support for the deep sea water and fucoidin composite liquid to research and develop health care products and drugs for preventing and treating the metabolic diseases and further can provide significance and enlightenment for high-valued utilization of marine resources of deep sea water, brown alga and the like.

The invention discloses application of cyanidin-3-O-glucoside in preparing medicines for preventing and/or treating male genital diseases caused by acrylamide and/or glycidamide. Based upon research results, C3G (the cyanidin-3-O-glucoside) can take an effective intervention effect on injury of R2C cells caused by AA or GA and can inhibit R2C cell oxidative stress functional lesion caused by the AA or GA, so that the survival rate of the cells is increased and progesterone synthesis is improved. The C3G can take a relatively good intervention protective effect on R2C cell activity declination, cell apoptosis, progesterone function expression injury and the like exposed by the AA or GA, and the optimum intervention concentration is 10-50[mu]M (M refers to mol/L). Upon research results, the cyanidin-3-O-glucoside provides a novel application;and moreover, the cyanidin-3-O-glucoside provides an important basis for preventing and treating the male genital diseases caused by the AA or GA in human bodies; therefore, the cyanidin-3-O-glucoside has an important research significance.