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185 results about "Intervention treatment" patented technology

An intervention is a carefully planned process where family, friends and others involved in the person’s life gather together to tell the person about the effect of their addiction and ask him or her to accept treatment. The intervention usually offers a prearranged treatment action plan with clear steps,...

Human-body health function-status evaluating model

The invention relates to a human-body health function-status evaluating model, relates to an evaluating method for comprehensively evaluating the functional level of a human body and belongs to the category of health evaluation. The construction of the evaluating model comprises the establishment of seven modules, i.e. a brain-cognizing function module, a metabolic function module, a traditional-Chinese-medicine symptom-identifying module, a psychological function module, a social-adapting function module, a cardio-pulmonary function module and a movement function module and the establishment of a specific testing project, an index system and a specific index under each module and a testing-project evaluating standard. The score evaluation of the whole module is finally obtained through each-step index evaluation, weight determination and calculation step by step. The integral comprehensive evaluation and the evaluating result of each module are all shown by corresponding evaluation reports. Functional-status levels in the aspects of physiology, psychology and social adaptation of the human body can be obtained through the health function-status evaluation of the human body, so that potential health hazards are found in advance, and intervention treatment is carried out as early as possible, so as to guarantee the physical and psychological function-status health of the human body.
Owner:陈立典

Rehabilitation therapy determination method and device, storage medium and electronic equipment

PendingCN111105859AReal-time monitoring of target index parametersKnow your healthMedical communicationPhysical therapies and activitiesDiseaseCritical illness
The invention belongs to the technical field of computers, and relates to a rehabilitation therapy determination method and device, a computer readable storage medium and electronic equipment. The method comprises the following steps: acquiring a target index and an object identifier, and sending a parameter acquisition request carrying the object identifier; receiving a target index parameter corresponding to the target index based on the parameter acquisition request; inputting the target index parameter into a pre-trained machine learning model to enable the machine learning model to outputa target therapy; obtaining an evaluation standard corresponding to the target index, and if the target index parameter does not meet the evaluation standard, generating early warning information corresponding to the target therapy; and adjusting the target therapy according to the early warning information so as to carry out corresponding rehabilitation training. On one hand, medical staff monitor target index parameters of an object in real time and know the health condition of the object; on the other hand, accurate treatment measures and methods are recommended to medical staff, passive rescue is changed into active intervention treatment, and great influences are achieved on prevention against serious diseases.
Owner:TAIKANG LIFE INSURANCE CO LTD

Digital radial artery compressing hemostasis device

The invention relates to a digital radial artery compressing hemostasis device. The device comprises a wound surface fixing baffle, a hemostasis module detachably arranged on the inner side surface of the wound surface fixing baffle, a hand back fixing baffle arranged opposite to the wound surface fixing baffle, and an air bag compressing module arranged on the hand back fixing baffle and matched with the hemostasis module for use, wherein an integrated control unit is packaged in the wound surface fixing baffle, and is electrically connected with the hemostasis module and the air bag compressing module respectively. The device is used for realizing the compressing hemostasis on the wound of a patient through the coronary artery intervention treatment by virtue of the radial artery path. Compared with the prior art, the digital radial artery compressing hemostasis device is simple and compact in integral structure, and is economical and practical, the overlarge pressure can be avoided under the premise of stopping bleeding through the precise electronic control, therefore, the comfort level of a patient is greatly promoted, the compressing shifting can be effectively avoided, the use is convenient and rapid, the industrial production and manufacturing can be realized, and thus the digital radial artery compressing hemostasis device has a very good application prospect.
Owner:冯小弟 +1

Interventional medical instrument delivering system

The invention discloses an interventional medical instrument delivering system. The system comprises a catheter with a hemostasis valve of which an opening is adjustable, the catheter comprises a pipe fitting and a hemostasis valve main body, and the near end of the pipe fitting is connected with the far end of the hemostasis valve main body; the system further comprises a silica gel ring and a screw cap, the screw cap is connected with the hemostasis valve main body through a thread at the near end of the hemostasis valve main body, and the size of an opening formed in the near end of the hemostasis valve main body is adjusted by rotatably compressing or loosening the silica gel ring through the thread; the side face of the hemostasis valve main body is provided with a side hole used for being connected with a hose and a three-way valve, and an injection syringe can be connected to the hemostasis valve main body through the three-way valve to inject medicine. According to the interventional medical instrument delivering system, adjusting operation on the opening of the hemostasis valve of the catheter is easy and convenient, the condition that blood overflows and gas enters the body of a patient in the using process can be avoided, an operator can conveniently inject medicine to the patient in case of need, therefore, the catheter intervention treatment effect can be effectively improved, the operation safety is improved, and the operation success rate is increased.
Owner:SHENZHEN KYD BIOMEDICAL TECH CO LTD

PCR (Polymerase Chain Reaction) specific primer, detecting kit and detecting method of benign and malignant thyroid nodule associated gene

The invention discloses a PCR (Polymerase Chain Reaction) specific primer, a detecting kit and a detecting method of a benign and malignant thyroid nodule associated gene. Sequences of the PCR specific primer of the thyroid nodule benign and malignant associated gene are as shown in SEQ ID NO:1 to SEQ ID NO:54. The benign and malignant thyroid nodule associated gene disclosed by the invention is closely related to pathological indexes of cases of a benign thyroid nodule and a malignant thyroid nodule and can be used as a biomarker for carrying out benign and malignant thyroid nodule classification on a patient suffering from the thyroid nodules, and effective basis can be provided for clinical individual intervention treatment. The PCR specific primer, the detecting kit and the detecting method, disclosed by the invention, are capable of simultaneously detecting multiple benign and malignant thyroid nodule associated genes of multiple samples, and the detecting efficiency and the accuracy can be effectively increased; meanwhile, the cost is reduced, and the operating steps are simplified.
Owner:GUANGDONG GENERAL HOSPITAL +1

System for synchronizing transcranial ultrasonic stimulation and electroencephalography recording of human body

InactiveCN107362465AAchieving Sequential Ultrasound StimulationUltrasound therapyDiagnostic recording/measuringEngineeringRadio frequency
The invention provides a system for synchronizing transcranial ultrasonic stimulation and electroencephalography recording of the human body, which comprises a computer (110) containing control software, a signal generator (130), a radio frequency amplifier (140), an ultrasonic transducer (150), a synchronization control module (120), a transducer-scalp coupling module (151), an electroencephalography system (160) and a signal receiving terminal (161), and is characterized in that real-time communication between the signal generator (130) and the electroencephalography system (160) can be realized by using the synchronization control module (120), and complete synchronization of ultrasonic stimulation and electroencephalographic signal collection is realized. The system provided by the invention for synchronizing transcranial ultrasonic stimulation and electroencephalography recording of the human body can be applied to basic brain cognitive function research and clinical brain disease intervention treatment research, can realize synchronization of ultrasonic stimulation and electroencephalographic signal recording and solves the technical problems of multi-channel synchronous or asynchronous independent ultrasonic stimulation and corresponding electroencephalographic signal synchronous recording and stimulation marking.
Owner:SHANGHAI JIAO TONG UNIV

Intelligentize myopia detection and intervention treatment integration platform

The invention discloses an intelligentize myopia detection and intervention treatment integration platform characterized by comprising a liftable trolley, an optical flat, a one-dimensional electric control translation bench, a face holder, a projector, a fluorescent lamp, an interactive keyboard, a lower computer and a host computer; the intelligentize myopia detection and intervention treatment integration platform can improve the disadvantages of existing myopia inspection schemes, and can improve myopia inspection automation, intellectualizing and networking level; in addition, a scientific myopia recovery training scheme is combined so as to help teenagers to improve myopia conditions through a lossless method.
Owner:中科合肥技术创新工程院

Refrigeration medicine dual-purpose intervention therapeutic apparatus for medical oncology

The invention relates to a refrigeration medicine dual-purpose intervention therapeutic apparatus for the medical oncology, and belongs to the technical field of medical apparatuses and instruments. The refrigeration medicine dual-purpose intervention therapeutic apparatus comprises a multifunctional combined box, a therapeutic box supporting device and an on-off operation panel, wherein a combined box supporting plate is arranged on the lower side of the multifunctional combined box, a combined box lifting pushing column is arranged on the lower side of the combined box bearing plate, a combined box lifting pressure pump is arranged on the lower side of the combined box lifting pushing column, a push piston is arranged in the combined box lifting pressure pump, an anti-falling reinforcement bottom plate is arranged on the lower side of the combined box lifting pressure pump, and a foot-stepping type pressure pump switch is arranged on the right side of the anti-falling reinforcement bottom plate. The refrigeration medicine dual-purpose intervention therapeutic apparatus is complete in function and convenient to use; when the tumor intervention treatment is conducted, operation is easy and convenient, time and labor are saved, and the working difficulty of medical staff is lowered.
Owner:陈大伟

Electroencephalography combined VR device for intervention treatment of children with hyperactivity and attention defect

The invention discloses an electroencephalography combined VR device for intervention treatment of a children with hyperactivity and attention defect. The device includes VR glasses, a portable intelligent terminal and a wireless electroencephalography collecting cap. The wireless electroencephalography collecting cap comprises an electrode cap body, a plurality of removable dry electrodes, an electroencephalography amplification device, an electroencephalography filtering device, an analog-to-digital conversion device, a wireless transmission device and a processor. According to the device, acorresponding intervention treatment program is developed according to the activation degree of a key brain area of a functional network obtained by the electroencephalography and the connection strength of brain areas, and the VR glasses are utilized to provide sensory stimulation such as visual and auditory sense for a user, so that the user has an immersion sense and better focuses on treatment and rehabilitation.
Owner:CHANGZHOU UNIV

Balloon microcatheter with detachable tip

The invention relates to a balloon microcatheter with a detachable tip. The balloon microcatheter comprises a microcatheter body, one end of the microcatheter body is communicated with a catheter base, and the other end of the microcatheter body is connected with the detachable microcatheter tip; a cannula is coaxially arranged outside the microcatheter body, and the two ends of the cannula are communicated with the catheter base and an inflatable balloon on the microcatheter body respectively. The balloon microcatheter has the advantages that the curative embolization rate of minimally invasive intervention treatment of cerebrovascular malformation can be increased, complications caused when a liquid emboliaztion agent flows back and hemorrhage related to incomplete embolization can be reduced, the treatment process is simplified, and the economic burden is relieved.
Owner:SHANGHAI CHANGHAI HOSPITAL

Novel interspinous process fixing device

The invention relates to a novel interspinous process fixing device. The novel interspinous process fixing device comprises an interspinous process fixator and a conveying device, wherein the interspinous process fixator comprises a flexible and foldable bag (100) and a filling material (200), the near end of the bag is provided with an injection hole (110), the conveying device comprises a conveying pipe (310), the injection hole (110) is in detachable connection with the far end of the conveying pipe (310), the filling material (200) is injected thorough the conveying pipe (310) and the injection hole (110) so as to spread the bag to form the interspinous process fixator, the part, positioned between two spinous processes, of the interspinous process fixator forms a support section, and the parts, positioned on the two sides of the spinous processes, of the interspinous process fixator protrude out, so that the movement of the interspinous process fixator between two spinous processes is limited. According to the novel interspinous process fixing device, through a minimally invasive method, the novel interspinous process fixing device is released after being conveyed between the spinous processes, then the filling material is injected, so that the fixation of the spinous processes is realized, and therefore, the micro-traumatic intervention treatment is realized, and the trauma to the patient is small.
Owner:NINGBO HICREN BIOTECH

Liver cancer biomarkers and application thereof

The invention relates to biomarkers miR-182-5p, miR-363-3p and miR-378a-3p which are beneficial to liver cancer diagnosis, as well as application thereof for preparing kits for screening liver cancer or assisting pathological identification and clinical diagnosis of liver cancer. The kit comprises a reverse transcription system and a primer system, wherein the reverse transcription system comprises reverse transcriptase, a reverse transcription system buffer and an RNA enzyme inhibitor; and the primer system consists of the stem-loop structure reverse transcription primers and amplification primers of miR-182-5p, miR-363-3p and miR-378a-3p and the amplification primers of U6 snRNA. The close correlation between the miRNA and clinical case indexes of liver cancer, determined by the invention, can serve as a biomarker to be used for screening and diagnosing liver cancer, an effective basis is provided for clinical individualized intervention treatment. The biomarker has the advantages of high quantification accuracy, convenience in clinical application, convenience in material preparation and noninvasiveness and can be used for continuous in-vitro detection.
Owner:ZHEJIANG SCI-TECH UNIV

Detection kit for detecting relative expression level of PML-RAR (alpha) fusion gene by use of fluorescent quantitative PCR (polymerase chain reaction) technology

The invention relates to a detection kit for detecting the relative expression level of PML-RAR (alpha) fusion gene by use of fluorescent quantitative PCR (polymerase chain reaction) technology. The detection kit comprises the following materials in part ratio: red blood cell lysis buffer, TRIzol, chloroform, absolute ethyl alcohol, reverse transcription PCR reagent, detection system PCR reaction liquid, positive control substance and negative control substance. The kit provided by the invention has the advantages that the precision is high, the result is convenient to read, both the amplification efficiency and the rate reach the best level and the like; the complicated condition grope link is omitted; and the experimental efficiency is greatly improved. The kit has good specificity and high sensitivity and is easy and convenient to operate according to the test. The detection kit is favorable for the trace residue detection of the PML-PAR (alpha) (type L / type S) fusion gene in a clinical APL (acute promyelocytic leukemia) patient, and has great importance in performing timely intervention therapy to avoid hematological recurrence, adjusting the therapeutic schedule, evaluating the therapeutic effect, predicting the prognosis and preventing clinical recurrence.
Owner:FUZHOU ADICON CLINICAL LAB INC

Depth scanning and information analysis-based upper limb lymphedema monitoring system

The invention belongs to the technical field of medical devices and particularly discloses a depth scanning and information analysis-based upper limb lymphedema monitoring system. The system comprises three parts including a scanning platform, a software analysis system and a cloud platform, wherein the scanning platform obtains depth and color data of upper limb of a patient suffering from edema and is controlled to run by the software analysis system; the software analysis system performs automatic grading diagnosis on the edema through depth scanning, image processing and information analysis; a doctor performs intervention treatment on the patient through a diagnosis result; the cloud platform stores the data of the scanning platform and the software system, and creates a personalized archive for the patient; and the doctor can perform remote medical treatment on the patient according to the cloud platform. According to the system, the multifunctionality and high efficiency of edema monitoring can be realized; edema assessment is performed by adopting multi-feature fusion analysis, and comprehensive analysis is performed through multiple features such as space, color, texture and the like, so that the system is superior to a current measurement form for a single index of the edema; and the system is low in cost, small in occupied space and convenient to use, and is of important significance for popularization and use in families and hospitals.
Owner:FUDAN UNIV

Hardness-controlled intelligent conduit for clinical intervention treatment

InactiveCN102058927ASolve the problem of hardness mismatchHelps fixCatheterCoatingsSignal onYoung's modulus
The invention discloses a hardness-controlled intelligent conduit for clinical intervention treatment. The conduit comprises an external conduit (1) and an internal conduit (3); a main body has the conventional conduit structure; and a metal enhancement layer (2) is arranged on an outer wall of the internal conduit (3); a structure containing a temperature sensitive high polymer layer also can be adopted, and a metal resistive layer (5) is arranged on the outer wall of the internal conduit (3); and a temperature sensitive high polymer layer (4) is coated on the external conduit (1). By applying a voltage or current signal on the metal enhancement layer (2) or the metal resistive layer (5), a local thermal effect is generated, the temperature of the temperature sensitive high polymer layer is raised, and Young modulus (also called hardness) is reduced. After an electric signal is cut off, the temperature of the polymer layer can be continuously reduced, while the hardness of the conduit is gradually increased to reach the initial hardness. The hardness-controlled intelligent conduit can greatly reduce the cost of frequently replacing the conduit, reduces the difficulty and risk of an operation, and shortens the operation time.
Owner:SOUTH CHINA UNIV OF TECH

Instrument system for digitalized intervention treatment of autistic children

InactiveCN103977495AMore professional and effective treatment and rehabilitation methodsProfessional and more effective treatment and rehabilitation meansSleep inducing/ending devicesCrowdsHearing perception
The invention discloses an instrument system for digitalized intervention treatment of autistic children and relates to a digitalized intervention instrument system for treatment of child autism. The instrument system consists of a health cloud platform, a smart home device, a home nursing customer service system and a remote consultation system, wherein the smart home device comprises a home computer and a mobile terminal and is provided with a login module, a training module and a communication module, and the training module comprises a continuous attention training template, a visual perception training template, a logic and thought template and a numerical concept and memory skill template. The instrument system is an instrument system which is applied to integral visual and hearing sense training for treatment of child autism and can provide a more professional and effective treatment and rehabilitation means for people who suffer from development behavior disorder.
Owner:广州市忆明科学仪器有限公司

Combined multiple-antenna and heat-field method for microwave intervention treatment of tumor

The combined multiple-antenna and heat field method for microwave intervention treatment of tumor includes the following steps. In the first step, the real-time 3D solidification heat field distribution of single antenna under different radiation power is obtained via measurement and calculation. In the second step, 3D solidification heat field distribution data base is found out for two or more antennas via permutation and combination to establish computer model and analysis with the limited element software based on the conditions of antennas, power, time of different power and blood stream perfusion rate of cancerized tissue. In the third step, the temperature boundary condition for the treatment after being 3D reconstructed is added into the heat field distribution data base in different conditions to form in the computer real-time heat field distribution data and corresponding 3D solidification heat field illustration under the different condition parameters.
Owner:广东世荣兆业股份有限公司 +1

Application of serum miRNA biomarker

The invention provides application of a serum miRNA biomarker, and relates to biomarkers. The serum miRNA biomarker comprises at least one of miR-34c, miR-1275, miR-375, miR-410 and miR-758. The serum miRNA biomarker can be applied to preparation of a reagent for detecting oligospermia and azoospermia. A serum miRNA biomarker composition comprises at least one of the miRNA and sequences of reverse transcription primers, forward primers and reverse primers of each miRNA, and can be applied to preparation of a reagent for detecting oligospermia and azoospermia. The determined close correlation between the miRNA combination and indexes of oligospermia and azoospermia cases can be used as the biomarker to screen and diagnose patients with oligospermia and azoospermia, and an efficient basis is provided to clinical individual intervention treatment.
Owner:XIAMEN UNIV

Base station and PTN (Packet Transport Network) networking based automatic startup method thereof and RNC (Radio Network Controller)

The invention discloses a base station and a PTN (Packet Transport Network) networking based automatic startup method thereof and an RNC (Radio Network Controller). The PTN networking based automatic startup method comprises the following steps of receiving an ARP (Address Resolution Protocol) broadcast message; performing resolution on the ARP broadcast message; sending a DHCP (Dynamic Host Configuration Protocol) request to the RNC; obtaining a base station IP (Internet Protocol) address from the RNC; obtaining the base station configuration information; performing configuration and startup according to the base station configuration information. According to the base station and the PTN networking based automatic startup method thereof and the RNC, the network maintenance personnel only need to achieve the station opening and updating operation in a maintenance machine room and an RNC machine room after the station building of a construction party is achieved and do not need to perform the station going operation and accordingly the human power time waste of the intervention treatment through the manual station going is reduced and the engineering cost of the second station going of the network maintenance personnel is reduced.
Owner:DATANG MOBILE COMM EQUIP CO LTD

Method and device for detecting body haemodynamics response in in-vitro counterpulsation treatment

ActiveCN110384485ALow costEvaluation of blood vesselsCatheterBlood flowHaemodynamic response
The invention discloses a method and device for detecting body haemodynamics response in in-vitro counterpulsation treatment. The detection method comprises the steps that physiological information ofa sampler is acquired, and blood vessel and blood flow state data before and in in-vitro counterpulsation treatment are acquired respectively; an arterial tree is segmented based on an arterial treestructure model, blood segment length and radius data of a healthy volunteer are acquired, a baseline reference value is set, and an arterial tree geometric solution model is constructed; and boundaryconditions and correction and calibration conditions are calculated and set, flow and pressure pulse wave distribution of each position of the arterial tree is calculated on the basis of the pulse wave transmission theory and the model, and the blood perfusion and blood pressure levels of target blood vessel segments and visceral organs before and in the in-vitro counterpulsation treatment are calculated. The method and device can be used for noninvasive, real-time and effective analysis of the immediate haemodynamics effect of the in-vitro counterpulsation intervention treatment, and break the technical bottleneck of lack of an effective immediate haemodynamics effect evaluation method in the current in-vitro counterpulsation treatment.
Owner:THE EIGHTH AFFILIATED HOSPITAL SUN YAT SEN UNIV

IgG subtype typing detection reagent card, and preparation method thereof

InactiveCN105067820AEasy to classify and detectQuick Classification DetectionBiological testingDiseaseHemolysis
The invention relates to an IgG subtype typing detection reagent card, and a preparation method thereof. The preparation method comprises following steps: gel suspension medium preparation; polyacrylamide dextrangel screening; antibody selection; and preparation, packaging, and sealed preservation of a gel containing IgG antibodies. Application range of the IgG subtype typing detection reagent card and the preparation method is wide; sensitivity, specificity, and stability are high; and the IgG subtype typing detection reagent card possesses significant importance on in-time analysis, determination, and intervention treatment of hemolysis disease of fetus and newborn.
Owner:JIANGYIN LIBO MEDICINE BIOTECH

Establishment method of animal model for acute Stanford A-type aortic dissection (AD) accompanied with MODS (multiple organ dysfunction syndrome)

The invention provides an establishment method of an animal model for acute Stanford A-type aortic dissection (AD) accompanied with MODS (multiple organ dysfunction syndrome), a use of emodin for preparing a medicine for treating acute Stanford A-type AD accompanied with MODS as well as a viscera protective agent for acute Stanford A-type AD accompanied with MODS. In the invention, an AD surgery method is improved and meanwhile manually controlled hypertension is formed by continuously pumping adrenaline into veins so as to promote expansion of the AD stripping range and accelerate disease progression, thus acute Stanford A-type AD accompanied with MODS can be rapidly formed so as to successfully make the model. The animal model for acute Stanford A-type AD accompanied with MODS creates conditions for further deep research in application foundation and intervention treatment.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV +2

Cranberry, inulin and probiotic solid beverage and preparation method thereof

The invention discloses a cranberry, inulin and probiotic solid beverage and a preparation method thereof. The solid beverage comprises composite probiotics, cranberry juice powder, black currant juice powder, inulin, erythrite and sucralose. According to the cranberry, inulin and probiotic solid beverage, intestinal flora adjustment, intestinal flora treatment, urinary tract infection and vaginainfection are firstly used as a whole to be subjected to intervention treatment, and short-term probiotic intervention is provided; and besides, establishment of normal microecology is emphasized forinternal probiotics. Besides, the inulin is added, and when being used as probiotics for culturing hosts, the inulin can protect the genital tracts healthy. The cranberry, inulin and probiotic solid beverage disclosed by the invention can protect vagina when being taken by women, and urethra health is emphasized. The cranberries are added, so that the probability of host autogenous infection is reduced. The solid beverage made by the preparation method disclosed by the invention is good in solubility, and takes effect quickly after being taken by human bodies.
Owner:河北朗益生物科技有限公司

Femoral artery direct puncture needle

InactiveCN101513357AAddressing issues that increase painSurgical needlesTrocarIntervention treatmentSeptal wall
The invention discloses a femoral artery direct puncture needle, comprising an integrated cylindrical needle body and needle handle, a separation wall is arranged in the inner channel, the inner channel is axially divided into a left channel and a right channel which are independent, the port of the left channel is an inclined left contrast channel outlet, a left contrast channel is arranged at the needle handle part of the left channel, the port of the right channel is a right contrast channel outlet which is in backward direction with the left contrast channel outlet, a right contrast channel is arranged at the needle handle part of the right channel, the left channel and the right channel are provided with an unidirectional haemostasis valve respectively, the ports of the right contrast channel and the left contrast channel are respectively provided with a heparin cap. When the puncture needle is used for the intervention treatment, even though the puncture needle enters the femoral artery, the seal wire is ensured to enter the target blood vessel, the invention solves the problem that the puncture is done again because the seal wire enters the femoral artery after radiography, even the operation is failure and the patient feels the pain.
Owner:祝慧鹏 +1

AAV9-CIP virus of expressed neurodegenerative disease protection peptide and preparation method of AAV9-CIP virus

The invention discloses a preparation method of an AAV9-CIP virus of expressed neurodegenerative disease protection peptide. The preparation method comprises the following steps that 1, a Myc-CIP primer is designed, and Myc-CIP gene segments are obtained; 2, plasmid pCR2.1-Myc-CIP is obtained; 3, plasmid pEGFP-C2-Myc-CIP is obtained; 4, plasmid pAAV-hSynapsin-GFP-Myc-CIP is obtained; 5, the AAV9-CIP virus is obtained. The invention aims at providing the AAV9-CIP virus, capable of being specifically expressed in central nervous system neuron, of neurodegenerative disease protection peptide. Due to the fact that a neurotoxic compound CDK5 / p25 generated in the lesion process of the nervous system neurodegenerative disease can be specifically inhibited by CIP, the CIP virus capable of being used for targeted intervention treatment of the nervous system neurodegenerative disease, such as the Alzheimer's disease and Parkinson's disease is established.
Owner:NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV

Cardiovascular intervention device

A cardiovascular intervention device comprises an outer tube body. An inner tube body is arranged in the outer tube body. A first through hole is formed in the middle of the top face of the inner tubebody. A second through hole is formed in the middle of the top face of the outer tube body. A guide tube is arranged in the first through hole. The side face of the guide tube makes close contact with and is matched with the first through hole. The upper end of the guide tube penetrates through the second through hole and is then located at the upper portion of the upper end of the outer tube body. The position, close to the lower end, of the side of the guide tube fixedly sleeves an annular first rubber plug. The outer ring of the first rubber ring makes contact with and is matched with theinner wall of the inner tube body. The cardiovascular intervention device is simple and ingenious in structure, the cleanliness of the operation surface during cardiovascular intervention treatment can be ensured, cross infection is avoided, required medicines can be conveniently injected into blood vessels of the patient in the treatment process, the medicines can be prevented from making contactwith outflow blood when injected, the injection safety and sanitation are ensured, and the cardiovascular intervention device is convenient to use and can be repeatedly used.
Owner:赵凤

Polypeptide analogue and application thereof in medicines for intervention treatment of cerebral hemorrhage

The invention discloses a polypeptide analogue and an application thereof in medicines for intervention treatment of cerebral hemorrhage. Polypeptide in the polypeptide analogue is Tat-CIRP-CMA, wherein Tat is a membrane-penetrating structure sequence of 11 amino acids, cold-induced protein CIRP is a 15 amino acid sequence with the highest affinity with MD2, and CMA is a signal peptide sequence of14 amino acids of targeted proteasome; and the polypeptide analogue has a good treatment effect on a cerebral hemorrhage model, and the polypeptide analogue studied in the invention possibly furtherplays an effective drug role.
Owner:NANTONG UNIVERSITY

Preparation method of osteoarthritis animal model

The invention relates to a preparation method of an osteoarthritis animal model. The method comprises the following steps: blending a matrix metalloproteinase-3 with normal saline so as to obtain a 5-10nmol / L matrix metalloproteinase-3 solution; blending a urokinase-type plasminogen activator with the normal saline so as to obtain a 2-4nmol / L urokinase-type plasminogen activator solution; then, blending the two solutions in proportion of 3:1 or 2:1 so as to obtain a mixed solution; injecting 0.5mL / kg of mixed solution into an articular cavity of an experimental animal. According to the method, the matrix metalloproteinase-3 and the urokinase-type plasminogen activator which are of conventional chemical reagents in a laboratory are taken as raw materials; the mixture is injected into the articular cavity of the animal, so that the rapid degeneration of cartilage tissues is generated. Thus, the pathogenesis process of osteoarthritis is simulated, thereby bringing great convenience for the research of an osteoarthritis intervention treatment technology. The method has the characteristics of being simple and convenient to operate, rapid in modelling, economical, practical, convenient in material obtainment, and the like.
Owner:王维山

MicroRNA (ribonucleic acid) specific expression profile and application thereof

The invention belongs to the fields of biological and medical examination, and relates to microRNA (ribonucleic acid) specific expression profile and clinical application thereof. Tumor recurrence after liver transplantation for liver cancer can be judged by five miRNAs or comprehensive indexes of the microRNA specific expression profile, accuracy rate reaches 77%, further, tumor recurrence and prognosis conditions of an integral case group can be judged, tumor recurrence and prognosis conditions can also be judged for patients after Milan delamination of the patients by the aid of the 5 miRNAs or the comprehensive indexes, accordingly, the microRNA specific expression profile can be used for screening patients with high tumor recurrence risks after clinical liver transplantation for liver cancer, assists in judging prognosis and realizing early diagnosis of recurrence, and provides a basis for early intervention treatment and implementation of individualized treatment.
Owner:SHANGHAI FIRST PEOPLES HOSPITAL

Puncture drainage device for cardiovascular intervention treatment

The invention discloses a puncture drainage device for cardiovascular intervention treatment, and the device comprises a connecting plate and a negative pressure bottle. Two sides of the connecting plate are each movably connected with a fixed plate, and the bottoms of the fixed plates are each fixedly connected with a housing. The tops of the fixed plates are movably connected with a pressure rod, and the bottom end of the pressure rod passes through the fixed plates and the housing and extends to the interior of the housing. One end, extending to the housing, of the pressure rod passes through the housing and extends to the bottom of the housing. The invention relates to the technical field of drainage devices. According to the invention, two sides of the connecting plate are movably connected with the fixed plates, and a part with a needle of the drainage device is absorbed to the body surface through a rubber sucking disc, thereby achieving the free operation of the angle of the needle for the drainage of the human body. The operation is very convenient. The opposite sides of the housing are each fixedly connected with the connecting rods, thereby achieving the acupuncture treatment of the human body. Moreover, the needle cannot be deflected, and a patient does not need to suffer more pain.
Owner:HENAN UNIVERSITY
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