The present invention discloses a biomarker combination and its application in predicting
breast cancer risk, specifically disclosing the application of a biomarker combination in preparing a product for predicting
breast cancer, wherein the biomarker combination is composed of ADPRS, ARMC8, ASCC3, B3GAT3, BLVRB, CA1, CDC37, DLG1, DSC3, DUSP3, EIF5AL1, EWSR1, GCNT3, H3-4, H3C1, H3C15, HBB, HBE1, HNRNPA0, HSPA6, ITGA6, MSL1, NUP155, PDCD10, PLBD2, PXDN, RDH10, RECK, RUVBL1, SAMHD1, SLC30A7, SMARCA5, SPG21, TCIRG1, TRIOBP, UFC1 and UROD. The marker combination provided in the present invention can be used as risk
estimation and detection for
breast cancer patients, has the advantages of high sensitivity and high specificity, and provides favorable
technical support for predicting the occurrence and development of breast
cancer. The development of corresponding prediction devices using the above-mentioned marker combinations can provide great convenience for early
clinical diagnosis or
intervention treatment.