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1439results about "Implantable neurostimulators" patented technology

External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders

An external stimulator adapted to be inductively coupled with an implanted lead-receiver is designed to deliver neuromodulation therapy for disorders including depression, migraine, partial complex epilepsy, generalized epilepsy, involuntary movement disorders, dementia, obsessive compulsive disorders, urinary incontinence, neurogenic / psychogenic pain and bladder control. The external stimulator containing limited number of predetermined programs packaged into the stimulator, giving the patient or caretaker a way to adjust the therapy within confined limits, or turn the device off. The pre-packaged programs contain unique combination of pulse amplitude, pulse width, frequency of stimulation, and on-off time. The programs are capable of being modified with a programming station connected to the pulse generator with a RS232-C serial connection.
Owner:NEURO & CARDIAC TECH

Methods and devices for renal nerve blocking

A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from the kidney. The device can be a drug pump eluting implant for targeted delivery of a nerve-blocking agent to the periarterial space of the renal artery.
Owner:MEDTRONIC ARDIAN LUXEMBOURG SARL

Closed-loop feedback-driven neuromodulation

InactiveUS7231254B2Reducing time and number of interactionSatisfactory treatmentHead electrodesImplantable neurostimulatorsNeurological signNervous system
A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.
Owner:CYBERONICS INC

New stimulation design for neuromodulation

The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder.
Owner:ADVANCED NEUROMODULATION SYST INC

Deep brain stimulation current steering with split electrodes

A device for brain stimulation includes a lead having a longitudinal surface, a proximal end, a distal end and a lead body. The device also includes a plurality of electrodes disposed along the longitudinal surface of the lead near the distal end of the lead. The plurality of electrodes includes a first set of segmented electrodes comprising at least two segmented electrodes disposed around a circumference of the lead at a first longitudinal position along the lead; and a second set of segmented electrodes comprising at least two segmented electrodes disposed around a circumference of the lead at a second longitudinal position along the lead. The device further includes one or more conductors that electrically couple together all of the segmented electrodes of the first set of segmented electrodes.
Owner:BOSTON SCI NEUROMODULATION CORP

Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more intracranial (IC) stimulating electrodes in accordance with treatment parameters. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.
Owner:CYBERONICS INC

Device and method for attenuating an immune response

Stimulation of one or more neurons of the sympathetic nervous system, including the splenic nerve, to attenuate an immune response, including an inflammatory immune response, is discussed. Devices and systems to stimulate the sympathetic nervous system to attenuate an immune response are also discussed. Devices discussed include pulse generators and drug pumps. Systems are described as optionally having one or more sensors and operator instructions. In specific examples, stimulation of the splenic nerve of pigs with a pulse generator is shown to be safe and effective in attenuating a lipopolysaccharide-induced immune response.
Owner:MEDTRONIC INC

External pulse generator for adjunct (add-on) treatment of obesity, eating disorders, neurological, neuropsychiatric, and urological disorders

An external pulse generator comprising a primary coil and adapted to inductively couple to an implanted receiving means, is designed to deliver neuromodulation therapy for disorders comprising obesity, eating disorders, anxiety and the like. The external pulse generator contains limited number of predetermined programs. These programs provide the patient or caretaker a means to adjust the therapy within confined limits, or turn the device off. The predetermined programs contain unique combination of pulse amplitude, pulse width, frequency of stimulation, and on-off time. In another mode of operation, the parameters can be individually adjusted and the stimulation therapy program can be “customized” for the patient, and stored in the memory. The programs are capable of being modified with a programming station connected to the pulse generator with a RS232-C serial connection. Additionally, the external pulse generator has two-way wireless capabilities, whereby enabling the physicians to remotely control the therapy programs of their patients using wireless internet. Moreover, the external pulse generator has proximity sensing and feedback regulation component to provide a constant therapy in accordance with the predetermined programs.
Owner:NEURO & CARDIAC TECH

Treatment of hypertension

Treatment of hypertension includes implantation of the discharge portion(s) of a catheter and / or electrical stimulation electrode(s) adjacent the tissue(s) to be stimulated. Stimulation pulses, i.e., drug infusion pulses and / or electrical pulses, are supplied by one or more implanted stimulators, through the catheter and possibly also a lead, tunneled subcutaneously between the stimulator and stimulation site. A microstimulator(s) may also / instead deliver electrical stimulation pulses. Stimulation sites include the carotid sinus and carotid body, among other locations. Treatments include drugs used for acute and / or chronic treatment of hypertension. In a number of embodiments, a need for or response to treatment is sensed, and the electrical and / or infusion pulses adjusted accordingly.
Owner:BOSTON SCI NEUROMODULATION CORP

Apparatus and method for treatment of neurological and neuropsychiatric disorders using programmerless implantable pulse generator system

System and method for neuromodulation therapy of neurological and neuropsychiatric disorders comprises an implantable lead and pulse generator system for providing the appropriate electrical stimulation to a cranial nerve such as the vagus nerve. The implantable pulse generator having prepackaged / predetermined programs stored in the memory of the pulse generator, and means for accessing these with an external magnet. The pulse generator adapted to selectively activate predetermined programs with the external magnet, thereby eliminating the need for an external programmer. The elimination of the external programmer resulting in significant cost reduction with essentially the same functionality.
Owner:NEURO & CARDIAC TECH

Electrical stimulation system and method for stimulating tissue in the brain to treat a neurological condition

InactiveUS20060004422A1Reduce and eliminate certain problem and disadvantageRemissionSpinal electrodesHead electrodesElectricityMedicine
According to one aspect, a stimulation system is provided for electrically stimulating a predetermined site to treat a neurological condition. The system includes an electrical stimulation lead adapted for implantation in communication with a predetermined site, wherein the site is brain tissue site. The stimulation lead includes one or more stimulation electrodes adapted to be positioned in the predetermined site. The system also includes a stimulation source that generates the stimulation pulses for transmission to the one or more stimulation electrodes of the stimulation lead to deliver the stimulation pulses to the predetermined site to treat a neurological disorder or condition.
Owner:ADVANCED NEUROMODULATION SYST INC

Apparatus for directionally stimulating nerve tissue

This invention relates to an apparatus and method for making such apparatus for providing controlled and directional stimulation patterns for tissue stimulation. The apparatus may be useful in stimulation nervous tissue in the brain, about the spinal cord, on nerve roots, about peripheral nerves, and in muscles, among others. The apparatus includes a implantable pulse generator connected to a lead. The lead has electrodes placed about a perimeter. In addition, the lead may include electrodes placed longitudinally along the axis of the lead. By applying charge differences between circumferentially distributed electrodes, a smaller stimulation field may be established. In addition, by stimulating between electrodes distributed longitudinally on the same side, a directional flow field may be established. Such leads are especially useful in deep brain stimulation as the region in which a stimulation field is strong enough to produce tissue stimulation is directional and minimized.
Owner:ADVANCED NEUROMODULATION SYST INC

Treatment of conditions through modulation of the autonomic nervous system

ActiveUS20050240241A1Decreasing and increasing parasympathetic and activityIncreasing parasympathetic activity/sympathetic activity ratioSpinal electrodesAngle modulation detailsNervous systemAnatomy
Methods are provided for treating a subject for a condition by modulating at least a portion of the subject's autonomic nervous system. In accordance with certain embodiments of the subject methods, at least a portion of a subject's autonomic nervous system is electrically or pharmacologically modulated in a manner that is effective to treat the subject for the condition. The subject methods find use in the treatment of a variety of different conditions, where such conditions include various disease conditions. Also provided are systems and kits for use in practicing the subject methods.
Owner:PALO ALTO INVESTORS

Technique for using heat flow management to treat brain disorders

A method of treating a brain disorder by heat transfer from brain tissue comprising the steps of surgically cutting a heat transfer aperture into a patient's skull, thereby exposing a predetermined portion of patient's brain; surgically implanting into said heat transfer aperture a heat pump having one or more electrical sensor elements and one or more temperature sensor elements; surgically implanting a heat transfer management unit in a body cavity of said patient such that a micro controller of the heat transfer management unit is connected to one or more activity sensor elements and one or more temperature sensor elements contacting brain tissue and connecting the heat transfer management unit to said heat pump via a lead bundle. Optionally, the heat transfer unit may be located external to the patient's body. Responsive to signals from one or more activity or temperature sensor elements, mathematical algorithms of the heat transfer management unit determine abnormal brain activity, causing the heat pump to remove heat from the brain tissue into a heat sink, thereby cooling the predetermined portion of the patient's brain. This technique utilizes acute hypothermia by means of a Peltier cooler or similar device to cool the brain temperature to reduce or prevent seizure initiation and / or propagation. The method may be used in association with brain stimulation and / or drug application to acutely avoid the occurrence of a seizure episode.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE

Clinician programmer for use with trial stimulator

Disclosed are systems and methods which provide an external clinician interface, such as through the use of a laptop computer or a personal digital assistant (PDA). The foregoing clinician interface may be used with trial stimulators well suited for use interoperatively and during patient trial. Stimulators of embodiments are adapted for use in providing stimulation to a plurality of tissues and / or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera.
Owner:ADVANCED NEUROMODULATION SYST INC

Closed-loop feedback-driven neuromodulation

InactiveUS7324851B1Reducing time and number of interactionSatisfactory treatmentHead electrodesImplantable neurostimulatorsNervous systemNEUROLOGIC REACTION
A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a □nervous system component.□ The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators, comprising intracranial (IC) stimulating electrodes and other actuators, in accordance with treatment parameters. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.
Owner:CYBERONICS INC

Stimulation of the amygdalohippocampal complex to treat neurological conditions

A system and / or method treating for a neurological disorder by brain region stimulation. The system and / or method comprises a probe and a device to provide stimulation. The probe has a stimulation portion implanted in communication with a predetermined brain region site. The stimulation portion of the probe may be implanted in contact with a predetermined brain region.
Owner:ADVANCED NEUROMODULATION SYST INC

Method of using a fully implantable miniature neurostimulator for vagus nerve stimulation

InactiveUS7167751B1Minimal surgical procedureSubstantial therapeutic benefitImplantable neurostimulatorsAnesthesiaSurgical procedures
A method of using a small implantable stimulator(s) with at least two electrodes small enough to have the electrodes located adjacent to the vagus nerve. The small stimulator provides a means of stimulating the vagus nerve when desired, and may be implanted via a minimal surgical procedure.
Owner:BOSTON SCI NEUROMODULATION CORP

Closed-loop feedback-driven neuromodulation

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.
Owner:CYBERONICS INC

Systems and methods for identifying the circumferential positioning of electrodes of leads for electrical stimulation systems

A lead assembly for an electrical stimulation system includes terminals disposed along a proximal end of a lead body and electrodes disposed along a distal end of the lead body. The electrodes include segmented electrodes. At least one distal marker is disposed along the distal end of the lead body. The distal marker identifies the circumferential position of at least one of the segmented electrodes along the lead body. The distal marker is aligned with at least one of the segmented electrodes along the longitudinal length of the lead body. At least one proximal marker is disposed along the proximal end of the lead body. The proximal marker is aligned with the distal marker along the longitudinal length of the lead body. The distal marker and the proximal marker are discontinuous with one another along the lead body.
Owner:BOSTON SCI NEUROMODULATION CORP

Active drug delivery in the gastrointestinal tract

Apparatus for drug administration is provided, including an ingestible capsule, which includes a drug, stored by the capsule, and an environmentally-sensitive mechanism, adapted to change a state thereof responsively to a disposition of the capsule within a gastrointestinal (GI) tract of a subject. The capsule further includes first and second electrodes, and a control component, adapted to facilitate passage of the drug, in response to a change of state of the environmentally-sensitive mechanism, through an epithelial layer of the GI tract by driving the first and second electrodes to apply a series of pulses at a current of less than about 5 mA, at a frequency of between about 12 Hz and about 24 Hz, and with a pulse duration of between about 0.5 milliseconds and about 3 milliseconds.
Owner:E PILL PHARMA

Nerve stimulation and conduction block therapy

A treatment apparatus and method have a stimulation electrode adapted for placement on a nerve of a patient at a stimulation site and a stimulation signal generator for generating a stimulation signal at the stimulation electrode and selected to electrically stimulate a nerve to induce bi-directional propagation of nervous impulses in a stimulated nerve. The apparatus includes a blocking member for placement on the nerve at a blocking site and creating localized conditions at the blocking site that at least partially diminish transmission of nerve impulses past the blocking site.
Owner:RESHAPE LIFESCIENCES INC
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