801 results about "Drug administration" patented technology

The invention relates to the technical field of tumor treatment, in particular to an intelligent decision-making system for tumor precise targeted medication based on individual mutation information, which comprises a data processing layer, a variation annotation and function prediction layer, a knowledge base integration layer and a scheme decision-making engine and report visualization module. According to the intelligent decision-making system for tumor precise targeted medication based on individual mutation information, a rule engine and a prediction model are combined, dynamic priority ranking is output, multi-model fusion decision making is achieved, and clinical scene deep adaptation is achieved by predicting primary and secondary drug resistance, calculating liver and kidney function adjusting dosage and generating a combined medication time sequence scheme; through an individualized drug delivery scheme, combination drug use optimization is achieved, a visual clinical report is generated, clinical executable operation is further strengthened, and through algorithm quantification, a dynamic knowledge graph, AI auxiliary decision making and a clinical operation closed loop, the next-generation technical research direction of a tumor precise drug use system can be represented.

The invention discloses a nursing pressure real-time monitoring system and method based on multi-modal data. The system comprises a data acquisition module, an intelligent analysis module, an analysis module and a real-time feedback module. The data acquisition module synchronously acquires physiological data, behavior activity data and environment situation data of nursing personnel and forms a nursing signal; the analysis module receives the nursing signal from the data acquisition module, receives the dynamic situation information from the intelligent analysis module, and generates a pressure state signal containing pressure event evaluation; the real-time feedback module receives the pressure state signal containing the pressure event evaluation from the analysis module, and generates and outputs a real-time feedback signal based on the pressure state signal. According to the nursing pressure real-time monitoring system and method based on the multi-modal data, the problem that traditional wearable equipment only collects physiological behavior data and cannot be associated with specific nursing situations such as drug administration operation and patient first aid can be solved.

A modular disease management system may provide medication management for a patient. The system may include a base configured to at least partially couple to a tissue site of a patient. The system may further include a medication bladder coupled to the base and configured to maintain medication. The system may further include a medication pump coupled to the medication bladder, comprising a conduit and muscle wire-actuated plungers, wherein the medication pump is configured to cause the medication to flow from the medication bladder through the conduit. The system may further include a cannula insertion device coupled to the medication pump via the conduit, wherein the cannula insertion device comprises a cannula, a spring, and a triggering component, wherein the cannula insertion device is configured to insert the cannula into the tissue site of the patient by actuation of the spring released by the triggering component.

A system for delivering an aerosolized drug to a patient. The system includes a holding chamber (108), suitable to contain a drug to be aerosolized, and a connect element (100) having first and second ends, the second end being opposite to the first end and being suitable to be connected to the holding chamber (108). The connect element further comprises one or more mating mechanism (102, 104, 112, 114, 118) proximal its first end. The system can also include a mouthpiece (400), a drug assembly (200) including a drug housing (216) and a drug cartridge (300), and a vaporizer (500).

The invention discloses a postoperative illness condition monitoring device for a patient in the anorectal department of traditional Chinese medicine, and relates to the technical field of postoperative nursing, the postoperative illness condition monitoring device comprises a drug administration monitoring device and an illness condition monitoring system, and the drug administration monitoring device comprises a drug administration barrel and a retention part; the illness state monitoring system comprises a sensor integration unit, an abnormity analysis unit, an alarm prompting unit and a drug administration suggestion unit; various post-operation data information of a patient is collected through the sensor integration unit, abnormity reminding signals are generated after abnormity judgment is carried out on the different data information, the patient and family members of the patient are reminded through the prompter arranged in a ward, meanwhile, reminding is sent to the remote medical terminal in a nurse station through the remote transmission module, and the patient is reminded through the remote transmission module. And the corresponding nursing suggestions are output to the remote medical terminal in the nurse station or the mobile terminal of the patient, so that the effect of monitoring the postoperative illness state in real time is achieved, negligence of manual observation is avoided, the corresponding suggestions can be quickly given, and effective measures are provided for medical staff and the patient.

The invention discloses an anesthesia strategy generation system fusing time sequence data and a knowledge graph, and relates to the technical field of medical information processing. The method specifically comprises the steps that five types of vital sign data including arterial blood pressure, electrocardio and electroencephalogram are collected, correction is conducted in combination with traction marks and electrotome interference characteristics, and an analysis result is output; the inference analysis module executes double-track processing based on the analysis value, one track evaluates cortical suppression, shock and ventilation risks and generates a risk report, and the other track performs reverse arbitration when the blood oxygen data is abnormal; constructing a knowledge graph fusing the efficacy nonlinear cooperation equation, the age sensitive parameters and the drug administration sequence influence; and the strategy generation module integrates the multi-source data to generate a drug execution track, and executes fast and slow closed-loop regulation and control based on a risk report and an arbitration result. According to the invention, the adaptation capability of the system to individual differences, the abnormal signal identification and processing capability and the intelligent response level of the anesthesia strategy are improved, and the accuracy and safety of clinical anesthesia are significantly enhanced.

The invention relates to the technical field of pharmacy management, in particular to a clinical pharmacy intelligent management method and system and a storage medium. The method comprises the following steps: acquiring total element data of a drug treatment chain in real time, wherein the total element data comprises a prescription instruction stream, a drug preparation parameter, a drug administration execution record and a patient physiological feedback signal; constructing a drug treatment chain dynamic evaluation engine; establishing a digital twinning mapping relationship between the administration operation and the clinical terminal for the total element data of the drug treatment chain by utilizing a drug treatment chain dynamic evaluation engine, and generating a drug digital relationship chain; and performing drug treatment chain breakage risk point identification on the drug digital relation chain based on a multi-dimensional deviation detection algorithm to obtain drug treatment abnormal risk points. Through real-time data acquisition, digital twinborn mapping and intelligent risk identification and intervention, intelligent management and accurate regulation and control of the drug treatment chain are improved, and intelligence and accuracy of drug treatment chain management are improved.

The invention discloses a step-by-step targeting placenta trophoblast micro-nano robot as well as a preparation method and application thereof. The micro-nano robot comprises a yeast cell wall of a bag-shaped structure, bio-enzyme unevenly distributed on the surface of the yeast cell wall and targeted placenta trophoblast drug-loaded nanoparticles located in the yeast cell wall. The surfaces of the targeted placenta trophoblast drug-loaded nanoparticles are connected with placenta-like chondroitin sulfate A binding polypeptides. Inflammation placenta tissue can be targeted through macrophages, the medicine is accurately delivered to placenta trophoblastic cells through the medicine-carrying nano-particles connected with the targeting peptide, step-by-step accurate targeting is achieved, the medicine does not penetrate through the placenta barrier to reach the body of a fetus, and high biological safety is achieved for pregnancy administration.

The invention discloses a tree shrew Alzheimer's disease modeling method. The method comprises the following specific steps: mixing an ethanol solution of Microcystin-LR with the concentration of 0.5 [mu] g / [mu] l with an amaninic acid solution, and injecting 2 [mu] l to Meynert basal nuclei on the two sides of a tree shrew respectively; and after drug administration is finished, normally feeding for 2 weeks to finish Alzheimer's disease modeling. The method comprises the following steps: under a sterile condition, sucking 200 microliters of sterile normal saline, adding the sterile normal saline into a small bottle containing 1mg of amanitine, repeatedly blowing and beating to completely dissolve the amanitine, and preparing a solution with the concentration of 5mu g / microliter; the Microcystin-LR solution is a product purchased in the market. According to the invention, a mixed solution of MC-LR (0.1 [mu] g) and IBO solution (3 [mu] g) is respectively injected to Meynert basal nuclei on both sides of the tree shrew, and a stable tree shrew AD model can be established after 2 weeks. After the medicine is administrated for 3 days, tree shrews have AD behavior expressions, such as drooping spirit and reduced activity; after two weeks, the tree shrew brain shows AD typical pathological expressions such as A beta deposition, increase of expression levels of multiple phosphorylation sites of Tau protein and the like.

The invention discloses an intelligent bandage integrating wound monitoring, drug administration and electrical stimulation. The intelligent bandage comprises a bandage body, a portable battery, a wound monitoring module, an intelligent drug administration module, an electrical stimulation module and a portable control module. The bandage body is of a double-layer structure, the inner layer is an antibacterial fiber layer, and the outer layer is a breathable waterproof layer. By means of the design, the wound can be kept dry, and external bacteria can be prevented from invading. The bandage body is further provided with a bandage elastic area which is used for adjusting the tightness of the bandage so as to meet the requirements of different wound parts. 3-6 sensors are arranged on the inner surface of the bandage body and used for monitoring key physiological indexes of a wound in real time, and accurate information is provided for treatment. The intelligent drug delivery module adopts a drug-loaded stimuli-responsive electroactive hydrogel fiber array and is arranged on the inner surface of the bandage body, and accurate drug delivery is achieved through a voltage modulation electrode. The electrical stimulation module adopts a pseudo convergence electric field configuration, is arranged on the inner surface of the bandage body, and is switched between the electrical stimulation electrodes through a timing relay so as to alternately push the wound to be closed. The portable battery supplies power to the portable control module, and the portable control module comprises an integrated microprocessor module, a wireless communication module and a lumped power management module and is connected with the intelligent drug delivery module, the wound monitoring module and the electrical stimulation module to achieve remote monitoring and personalized treatment.

The invention relates to the technical field of medical care informatics and precision medical treatment, and discloses a hemodialysis patient precision medication system based on multiple omics and big data, and the system comprises a multi-source data collection module which collects the multi-source heterogeneous data of a patient and carries out the standardization and integration processing; the drug metabolism analysis module is used for analyzing drug metabolism paths and individual differences through multi-omics data, constructing a drug metabolism polymorphic model and outputting gene metabolism capability grades and biomarker risk tags; the initial medication decision-making module is used for constructing an initial medication decision-making model based on a federal optimization framework of a momentum enhancement and robust aggregation mechanism, and outputting a personalized initial medication scheme for erythropoietin and a vein iron agent; and the drug dosage adjustment module is used for dynamically optimizing the time node and dosage adjustment opportunity of drug administration through an asynchronous federal reinforcement learning framework in combination with a prospective parameter correction strategy. According to the invention, the intelligent medication system with strong robustness and fine decision is constructed.

The invention discloses a metal polyphenol network modified drug-loaded radioactive microsphere as well as a preparation method and application thereof, radionuclides are labeled on different microspheres by a precipitation method or an adsorption method, and the metal polyphenol network is modified on the surface of the radioactive microsphere to improve the nuclide labeling stability and the synchronous drug loading capability of the radioactive microsphere. Subsequently, medicine molecules can be adsorbed to the modified radioactive microspheres to obtain the metal polyphenol network modified medicine-carrying radioactive microspheres. The metal polyphenol network modified drug-loaded radioactive microspheres prepared by the invention can solve the problems of radionuclide non-target shedding and DNA damage repair caused by nuclear drugs, avoid secondary drug administration, ensure that drugs directly and accurately reach tumor targets, and improve the drug delivery efficiency. And the selective internal irradiation therapy based on radioactive microsphere mediation is further promoted to play a more effective tumor treatment effect.

The invention relates to the technical field of medical care informatics, in particular to an automatic drug delivery system for first aid of hypoglycemia patients, comprising: a data acquisition module for acquiring a blood glucose level curve and an acceleration monitoring curve; the evaluation value determination module is used for determining a second evaluation value in an unconscious faint state according to the blood glucose level curve and the acceleration monitoring curve; the intensity value determining module is used for determining the first-aid intensity value of the hypoglycemia patient according to the second evaluation value and the target curve segment of the acceleration monitoring curve; the first-aid operation module is used for providing first-aid operation of the corresponding level for the hypoglycemia patient through the first-aid intensity value. According to the invention, the first-aid intensity value is determined, so that the drug delivery system for first aid makes the corresponding response operation, and the first-aid effect of the hypoglycemia patient is improved.

The invention relates to the technical field of pharmaceutical preparations, and provides a minoxidil film coating agent as well as a preparation method and application thereof. The minoxidil film coating agent provided by the invention comprises 40-60% of propylene glycol, 3-7% of polyvinyl alcohol, 20-30% of ethanol, 1-7% of minoxidil and the balance of water. According to the invention, propylene glycol is taken as a solvent, a plasticizer and a transdermal absorption enhancer, polyvinyl alcohol is taken as a film-forming material, and ethanol is taken as a volatile agent, after administration, ethanol is volatilized to promote film formation of polyvinyl alcohol, and propylene glycol enhances the plasticity of the formed film, so that the effect of reducing liquid medicine loss is achieved, the local medicine concentration is increased, and the bioavailability is improved. The minoxidil liniment disclosed by the invention has excellent skin permeability, can effectively convey a medicine to a required part, and can ensure that the medicine is released at a fixed position of the skin and is accurately administered in a medicine release process, so that the stimulation of liquid medicine flow to other parts is reduced, and a good treatment effect is achieved.

The invention belongs to the technical field of anesthesia depth regulation and control, and particularly relates to an anesthesia depth self-adaptive regulation and control method and system based on a dynamic time sequence model, and the system comprises a portable computer which is used for operating a program, receiving electroencephalogram time sequence data output by a signal collection device, receiving a pressing event of a handle, and obtaining efficacy information of an effect part; a channel gating result is generated based on the information and used for conducting category division on a drug administration adjustment request, gating is conducted through a shared code LSTM and a two-channel LSTM head and an effect room concentration vector and a hysteresis band, the problem of rhythm dislocation caused by exponential smoothing lag and induction-waking asymmetry is solved, mistaken up-regulation or mistaken down-regulation and overshoot are reduced, and the accuracy of drug administration adjustment is improved. And the adjustment convergence time is shortened, so that the anesthesia depth is more stably maintained in a target interval.

The utility model relates to the technical field of medical equipment, and discloses a transdermal drug delivery controlled release disc and a transdermal drug delivery device.The controlled release disc comprises a disc body, a central drug delivery cavity and an annular negative pressure adsorption cavity are formed in the disc body, and the negative pressure adsorption cavity is located on the outer side of the central drug delivery cavity; the inner top end of the negative-pressure adsorption cavity is provided with at least one convex rib, the upper space of the negative-pressure adsorption cavity is divided into at least two adsorption areas through the convex ribs, the adsorption areas are distributed in the radial direction of the disc body, and the negative-pressure adsorption cavity is provided with negative-pressure openings communicated with the adsorption areas; the negative pressure adsorption cavity is arranged to enable the skin to be stretched to the adsorption area under the negative pressure effect and to be attached to the surface of the adsorption area. According to the transdermal drug delivery controlled release disc, the technical effects of improving the adsorption stability of the disc body on the skin and reducing the possibility that the disc body falls off from the skin are realized, and the problem that the transdermal drug delivery controlled release disc is easy to fall off when being adsorbed and fixed on the skin in the related technology is solved.

The invention relates to the technical field of perioperative period management, and provides a post-craniotomy subcutaneous effusion puncture suction and administration device which comprises a lantern ring, a plurality of fixing sleeves are fixedly connected to the inner circumference of the lantern ring and surround the inner circumference of the lantern ring at equal intervals, an expansion air bag is fixedly arranged in each fixing sleeve in a sleeved mode, and the expansion air bags are fixed to the inner circumference of the lantern ring in a sleeved mode. Cotton gaskets are arranged on the inner peripheries of the multiple fixing sleeves, and the expansion air bag enables the cotton gaskets to abut against the forehead of the patient through expansion so that the lantern ring can be fixed to the forehead of the patient. The two traction arcs are arranged in a crossed and staggered mode, sliding grooves are formed in the middle ends of the traction arcs, and an expansion fixing piece is connected to the intersection of the two sliding grooves in a sliding mode. The device can be matched with a single person to carry out subcutaneous hydrops suction and medicine injection work after craniotomy, in the suction or medicine injection process, the device assists in fixing a needle head and carrying out syringe operation with two hands, multiple persons do not need to carry out stable hydrops suction and medicine injection operation, medical convenience is improved, and manpower consumption is reduced.

The invention discloses a gene engineering exosome and a slow release method and application thereof, the gene engineering exosome is derived from human adipose-derived stem cells, si-tgfbr2 is loaded in the gene engineering exosome, the si-tgfbr2 is specific siRNA aiming at a Tgfbr2 gene, and the gene engineering exosome can regulate and control proliferation of VSMCs, inhibit transformation of the VSMCs from a contraction phenotype to a synthetic phenotype when the VSMCs are stimulated, and inhibit the growth of the VSMCs. According to the present invention, the gene engineering exosome can be used to maintain the normal structure and the function of the blood vessel, and the sustained release effect of the content in the gene engineering exosome can be achieved by wrapping the gene engineering exosome in the PHA biodegradable material, such that the local treatment concentration can be easily stabilized, the drug administration frequency can be easily reduced, the lasting time of the treatment effect can be easily prolonged, and the treatment gene can be effectively delivered to the target cell; the treatment effect is improved; when being used for modifying a small-caliber artificial blood vessel, the small-caliber artificial blood vessel can be improved in biocompatibility and functionality, and can be prevented from being implanted into the blood vessel for remodeling unbenign hyperplasia stenosis; the invention not only provides a new thought and method for the treatment of vascular diseases, but also has important clinical application value and popularization prospect.

The invention discloses an intelligent decision-making method for a cerebral ischemia drug administration time window, and relates to the technical field of intelligent decision-making. The method comprises the following steps: S1, acquiring parameters, and setting a cerebral ischemia drug configuration scheme; s2, extracting a medicine characteristic parameter set and a medicine taking influence parameter set; s3, calculating a drug combination risk parameter set; s4, performing hierarchical classification processing on the drug combination risk parameter set, and performing drug correlation analysis; s5, performing weighted fusion on a correlation analysis result in combination with a drug influence attenuation rule, generating a drug administration time window evaluation parameter, and adding a label; and S6, according to the parameters, the labels and the configuration scheme, generating a cerebral ischemia drug administration time window intelligent decision scheme, and performing storage and backup. According to the method, by combining directional extraction of the drug characteristic parameter set and the drug taking influence parameter set with Pearson correlation algorithm screening, decision errors caused by data deviation are avoided.

The invention discloses a negative pressure drug delivery dynamic adjusting device for a wound surface and a using method thereof, and relates to the technical field of medical instruments and equipment.The negative pressure drug delivery dynamic adjusting device comprises a machine shell, a control module, a connecting module, a negative pressure module and a drug delivery module in the wound surface are installed in the machine shell, a collecting chamber is arranged on one side of the bottom of the machine shell, and a pressure stabilizing linkage control mechanism is further arranged in the machine shell; the pressure stabilization linkage control mechanism is used for dynamic regulation and control of negative pressure and drug administration in the wound surface; the connecting module is used for uniform negative pressure of the wound surface and drug administration in the wound surface; according to the scheme, multi-mode free combination is adopted, single negative pressure / in-wound drug delivery, synchronous linkage, reverse linkage and an alternating mode are supported, the full-period requirement from acute trauma to chronic repair is met, and intelligent parameter matching is conducted, for example, through pressure-flow closed-loop feedback, when the negative pressure value rises, the drug delivery flow speed in the wound is automatically reduced, and when the negative pressure value rises, the drug delivery flow speed in the wound is automatically reduced; when wound exudate is reduced, pulse negative pressure is triggered to promote microcirculation.

A method for delivering a therapeutic agent to a human brain by delivering systemically a therapeutic agent and applying low intensity pulsed ultrasound (“LIPU”) to the brain in the presence of circulating microbubbles. The therapeutic agent is delivered prior to applying LIPU if it has a plasma half-life of ≥1 h, and the therapeutic agent is delivered after applying LIPU if it has a plasma half-life of <1 h. In a second disclosed method, a first therapeutic agent is delivered systemically, LIPU is applied to the brain in the presence of circulating microbubbles, and a second therapeutic agent is delivered systemically. Also provided is a method for treating a brain disorder in a human by delivering a therapeutic agent systemically, administering a microbubble solution, and applying LIPU to the brain for a period of 1 min. to 30 min.

The invention relates to the technical field of medical instruments, and discloses anesthesia quantitative spraying equipment for the anesthesiology department. The piston push rod is arranged in the syringe and can slide in the syringe; the injection end head is arranged at the end part of the injection cylinder and is communicated with the injection cylinder; the connecting pipe is arranged at one end of the injection end, and a spraying head is fixedly mounted at one end of the connecting pipe; the injection tube is arranged at the position, close to the injection end head, of the injection cylinder and communicates with the injection cylinder, and the anesthesia quantitative spraying equipment for the anesthesiology department has the advantages that quantification is limited through movement, and compared with the operation mode that manual pressing type equipment depends on the hand force of medical staff, the operation efficiency is greatly improved; dose deviation caused by factors such as operation experience difference and hand fatigue can be effectively avoided, it is ensured that the anesthetic dose injected every time strictly conforms to a preset value, and the consistency of the administration dose is remarkably improved.

The present invention belongs to the field of drug research and development, and specifically discloses a method, storage chip and device for efficiently evaluating the efficacy of in vitro combined drug therapy. The present invention directly solves the problems of complexity and high cost of experiments and data processing in the existing drug development process by adopting an AI model and a simplified experimental mode. The AI ​​model optimizes concentration selection based on historical drug data, thereby reducing redundant concentrations and unnecessary number of experiments in the experiment, and improving the sensitivity and reliability of the evaluation. By simplifying the experimental design to single drug concentration point testing and a 3x3 combined drug matrix, the complexity and cost of the experiment are significantly reduced, while the speed of data processing and analysis is accelerated. The method disclosed in the present invention avoids excessive combined drug pre-testing by directly conducting single drug and 3x3 matrix combined drug testing, which can not only more effectively identify potential synergies between drugs, but also provide more accurate and practical data to support future clinical research.

The invention relates to the technical field of ultrasonic scalpels, in particular to an ultrasonic scalpel for pediatric surgery, which comprises a handle part, and a beveling blade surface, a main blade surface and an auxiliary blade surface which are arranged on the handle part, the auxiliary blade face extends from the cutter head end to the tail end to form a second transition blade face, the second transition blade face is designed to be an inwards-concave arc face, an assembling groove is formed in the handle portion, a capsule type flushing head is rotationally installed in the assembling groove in a damping mode, the capsule type flushing head is in a notch shape, and the capsule type flushing head is connected with the auxiliary blade face. The two ends of the capsule type flushing head are the output end and the tail end respectively, an open window communicated with the assembling groove is formed in the outer wall of the arc face of the second transition blade face, the output end of the capsule type flushing head is allowed to rotate out through the open window, and a first straight pipeline is arranged in the handle part in the direction from the cutter handle to the cutter head. The three-effect integrated function of debridement crushing, flushing dosing and waste liquid suction is achieved, flushing dosing can be conducted in time after debridement crushing, and a flushing channel in the tool bit is perfected.

The invention discloses a drug targeted delivery device and method, and belongs to the technical field of intelligent medical treatment. The device comprises the following modules: an intelligent targeted recognition module for accurately recognizing a gastric cancer specific molecular marker and improving the selectivity and specificity of targeted recognition in combination with a dynamic surface modification strategy; the microenvironment real-time monitoring module is used for monitoring key physiological parameters of the gastric cancer microenvironment in real time; the intelligent path planning module is used for dynamically calculating and optimizing a drug delivery path and realizing accurate drug positioning; the personalized drug administration regulation and control module is used for accurately predicting the drug dosage demand of an individual and dynamically and finely adjusting the drug administration amount in real time; the drug resistance risk management module is used for early warning a drug resistance risk in advance and automatically generating a personalized alternative drug administration strategy through multi-dimensional drug resistance analysis and real-time early warning; and the intelligent drug release module adopts a temperature-sensitive / pH-sensitive polymer shell layer and a nano valve to control drug release, so that precise gradient release of drug concentration is realized.

The invention relates to the technical field of pharmaceutical preparations, in particular to a rapamycin multiphase release or osmotic pump type weekly-effect oral controlled-release composition and a preparation method thereof, and the rapamycin multiphase release or osmotic pump type weekly-effect oral controlled-release composition comprises a quick release layer, a slow release layer and an osmotic pump structural design. According to the application, staged or constant-rate release of rapamycin within 168 hours is realized through a multi-phase release technology or an osmotic pump technology, and the problems that an existing preparation is large in blood concentration fluctuation, high in administration frequency and low in bioavailability are solved. The composition is suitable for treating hypertrophic cardiomyopathy of cats, significantly improves cardiac functions and reduces side effects and risks, is administered once a week, and is convenient to use. The invention further provides a storage method, and the product stability is ensured. The technical scheme has remarkable clinical advantages and application prospects.

The present invention provides an accurate delivery device and accurate drug administration control method for delivering a pharmaceutical aerosol. The accurate delivery device for delivering a pharmaceutical aerosol comprises: a housing, sized and shaped to be held in the hand of a user; a drug cartridge assembly, which can nebulize a set dose of drug into an aerosol, wherein an aerosol channel used for conveying the aerosol is formed in the drug cartridge assembly; a flow generator, which is used for generating positive pressure airflow for conveying the aerosol to the respiratory tract; and a control unit, which is used for receiving an operation instruction, driving the drug cartridge assembly to output the pharmaceutical aerosol, and driving the flow generator to generate positive pressure airflow, wherein the drug cartridge assembly, the flow generator, and the control unit are all accommodated in the housing. The present invention has the beneficial effects of being small in structure, easy to carry, convenient to use and capable of carrying out accurate drug administration.

A transdermal drug administration device comprises: a housing; a battery; an injection system; a movable connection part for providing fluid connection between the injection system and a reservoir containing an active ingredient intended to be administered; a pump system, the pump system being motorized so as to cause a fluid to circulate within a fluid network of the device; and an electronic system for controlling the driving of the pump system, the electronic system being provided with a mechanical switch for powering the pump system with a battery, wherein the movable connection part is moveable relative to the housing and the reservoir, the movable connection part jointly controlling the fluid supply of the pump and the power supply of the electronic system during the movement, at least part of the movement being performed by a human mechanical action.

The utility model relates to the technical field of medical instruments, in particular to a pulmonary artery wedge pressure balloon. The pulmonary artery wedge pressure balloon comprises a catheter and a balloon body, one end of the catheter is provided with an inclined and elastic bent section, the balloon body is arranged on the outer wall of the end of the bent section, an airflow cavity channel communicated with an inner cavity of the balloon body is formed in the catheter, and the airflow cavity channel penetrates out of the side wall of the other end of the catheter. The pulmonary artery pressure detector has the advantages that the structural design is simple and reasonable, the use cost is low, and the pulmonary vessel pressure information of a pulmonary artery hypertension patient can be effectively detected, so that medical staff can judge the drug effect of administration according to the information or accurately evaluate the interventional operation of the patient.

The invention discloses a subcutaneous administration intelligent health management system based on dynamic data, and relates to a medical instrument. According to the system, the data monitoring system, the drug delivery strategy calculation system and the subcutaneous drug delivery system are adopted for monitoring and processing health data and quickly responding to drug intervention, so that the problem that only health data can be monitored and health suggestions can be provided at the present stage, and abnormal health conditions cannot be handled in time is solved; according to the full-automatic management method of'detection, diagnosis and administration ', the compliance of a patient is improved; personalized and intelligent real-time administration calculation is achieved, the effect is guaranteed, meanwhile, the dosage of the medicine is reduced to the maximum extent, and side effects are reduced; the non-invasive transdermal drug delivery performed by using the microneedle system can reduce the problem of low bioavailability of the drug due to the effects of first pass metabolism and the like, and is more friendly to patients with dysphagia.