362 results about "Physiologic States" patented technology

The present invention includes a handheld device and a main device, wherein the handheld device is held by an athlete and the main device is moved with the athlete. Through a measuring device acquiring a physiological condition of the athlete and a movement state of the handheld device and transmitting thereof to the main device, the main device can produce an exercise indication signal according thereto, so that the athlete can obtain an exercise direction and also can manage the physical condition during exercise.

An wearable communications garment that includes one or more user-selectable inputs integrated into the garment. A sartorial communications apparatus may include a flexible material that is worn (e.g., as an undergarment) by the user and includes one or more interactive sensors that may be manually activated by a user, even through one or more intervening layers of clothing. The apparatus may also include one or more additional body sensors configured to sense a user's position, movement, and / or physiological status. The sensor(s) may be connected via a conductive trace on the garment to a sensor module for analysis and / or transmission. Methods of manufacturing the garments as well as methods of using the garments are also described.

PCT No. PCT / JP96 / 01254 Sec. 371 Date Apr. 2, 1997 Sec. 102(e) Date Apr. 2, 1997 PCT Filed May 13, 1996 PCT Pub. No. WO96 / 35368 PCT Pub. Date Nov. 14, 1996The present invention relates to a device for diagnosing physiological state based on blood pulse waves detected in the body. It is the objective of the present invention to provide a device which correctly diagnoses the current physiological state based on changes in physiological state measured over a specified period of time in the past while taking into consideration the cyclical variation exhibited in physiological state. In order to realize this objective, the device according to the present invention has as its main components: blood pulse wave detector 381 and stroke-volume-per-beat measurer 382 which respectively detect blood pulse wave and stroke volume in the body; blood pulse wave extraction memory 386 which extracts characteristic information from the detected blood pulse wave; memory 383 in which the physiological state calculated from the stroke volume and this characteristic information is stored; output portion 385 which outputs an alarm; and microcomputer 387 which controls each part inside the device. The microcomputer calculates the circulatory parameters based on characteristic information obtained from the waveform extraction memory, and stores the parameters in memory at specified time intervals. At these times, microcomputer 387 calculates the circulatory parameters from the stroke volume per beat and the characteristic information of the blood pulse wave at specified time intervals, and stores the parameters in memory 383. Further, microcomputer 387 reads out from memory 383 the circulatory parameters from a specified time interval in the past, and calculates the average value and standard deviation. Microcomputer 387 then determines whether or not the current circulatory parameters are within a specified range determined by their average value and standard deviation. When the circulatory parameters are determined to be outside this range, microcomputer 387 controls output portion 385 to sound an alarm.

An impedance model of tissue is useful for describing conductivity reconstruction in tissue. Techniques for determining and mapping conductivity distribution in tissue supply useful information of anatomical and physiological status in various medical applications. Electrical Impedance Tomography (EIT) techniques are highly suitable for analyzing conductivity distribution. Electrical characteristics of tissue include resistive elements and capacitive elements. EIT techniques involve passing a low frequency current through the body to monitor various anatomical and physiological characteristics. The system can interrogate at multiple frequencies to map impedance. Analytical techniques involve forward and inverse solutions to boundary value analysis to tissue characteristics.

A physiological status monitoring system includes a shirt and a stretchable circumferential band attached to the shirt. The stretchable band includes a respiration detector subsystem and signal transmission conductors. One or more sensors on the band are electrically connected to a signal transmission conductor. At least one sensor has an exposed electrode inside the shirt. The system includes a cover over the band and / or the one or more sensors. A connection subsystem on the band is electrically connected to the respiration detector subsystem and the signal transmission conductors and includes signal traces therefrom to a first connector accessible from outside the shirt. An electronics module is releasably attached to the shirt and includes a second connector which mates with the first connector. The electronics module includes a processing system and a transmitter. The remote display unit includes a receiver, a display, and a processing system.

The present invention provides systems and methods for monitoring in real time the physiological status of one or more subjects, especially subject engaged in potentially hazardous or dangerous activities. Systems include wearable items with one or more physiological sensors and a local data unit (LDU) operatively coupled to the sensors. The LDUs digitize and filter sensor data, extract physiological parameters, determine abnormal or not acceptable physiological conditions, and communicate to external monitoring facilities. The external facilities display status and data concerning monitored subjects. In preferred embodiments, communication between the LDUs and the external monitoring facilities dynamically adjusts to the condition of the subjects and to system changes such as subjects and external facilities entering and leaving and / or moving from place to place. The invention also provides program products for performing this invention's methods.

A method and apparatus for controlling a ventricular assist device are disclosed. The method includes the step of providing a ventricular assist device which can be defined in terms of operational parameters such as pump speed or current. Measuring at least one physiological parameter reflecting a physiological state corresponding to a patient. Correlating at least one physiological parameter measured from the patient to at least one operational parameter using an estimation method. Selecting a physiological state definable by desired values of the physiological parameters. Monitoring at least one operational parameter. Controlling input values of the operational parameter based on output from the monitoring step. The apparatus includes a pump driven by a motive drive and having an impeller. A sensor detects the value of an operational parameter of the pump. A processor provides a statistical correlation between patients physiological parameter and the operational parameter of the pump and adjusts the operational parameter to affect a predetermined optimal physiological state.

A noninvasive patient-specific method is provided to aid in the analysis, diagnosis, prediction or treatment of hemodynamics of the cardiovascular system of a patient. Coronary blood flow and pressure can be predicted using a 3-D patient image-based model that is implicitly coupled with a model of at least a portion of the remaining cardiovascular system. The 3-D patient image-based model includes at least a portion of the thoracic aorta and epicardial coronaries of the patient. The shape of one or more velocity profiles at the interface of the models is enforced to control complex flow features of recirculating or retrograde flow thereby minimizing model instabilities and resulting in patient-specific predictions of coronary flow rate and pressure. The invention allows for patient-specific predictions of the effect of different or varying physiological states and hemodynamic benefits of coronary medical interventions, percutaneous coronary interventions and surgical therapies.

The invention relates to a system for monitoring a cumulative physiological state and for predicting a target state under physical exercise, which system includes means for measuring a variable depicting the intensity of the exercise and for registering it relative to time, the control unit consisting of a user-interface device, which includes an input device and output device. Software means calculate the current value of the said cumulative physiological variable while second software means calculate the value of a selected output variable, which output variable is one of the following three variables: target state, future intensity, or duration of future exercise, the two other variables being given as initial variables.

Systems and methods for sonification, user influence through sound, and biofeedback, sonification of motion and physiological parameters during physical exercise and the use of music and sound in order to influence the emotional, psychological and physiological state of an exerciser, and the use of sonification and influence in a feedback loop to create a particular exercise experience for a user. A digital music player comprises physiological sensors, a controller, a user interface, a music decoder, a music playback modulator, and an audio data store. The user interface allows a user to specify target values for the physiological sensors as a function of time, the controller selects a playlist of audio data based on the target values, the music decoder decodes the audio data in a sequence corresponding to the playlist, and the music playback modulator causes the sequence and / or the decoding to be modified according to the values of the physiological sensor.

An efficient, objective, flexible and easily deployable system for conducting evaluations of mental and physiological state and recommending individualized treatment to improve said state is described. The method and system are based on commensurate measurement of mental functions, levels of stress and anxiety, and / or biologically active molecules such as neurotransmitters, immune markers including cytokines and hormones. The method and system are designed to assess an individual's cognitive function and the underlying physiology in order to delineate various disease processes, injuries, drug states, training stages, fatigue levels, stress levels, aging processes, predict susceptibility to stress and / or sleep deprivation, identify aptitude for training and / or characterize effects of any experimental conditions. The system and method may be used in recommending individualized treatment protocols, as well as to guide the treatment process by assessing the efficacy of such therapies in the clinical trials process.

A physiological status monitor has a monitor and an interconnected sensor that generates a sensor signal. The monitor computes physiological parameters responsive to the sensor signal and displays physiological parameters accordingly. In an embodiment, the monitor displays physiological parameter information across multiple patients in a cumulative pie chart format so that a caregiver can quickly discern and readily identify patients in need of immediate medical attention.

Device, system and methods for using body worn sensors to analyze human body motion. The device, often configured to be worn on the user's wrist, arm, neck, belt or other location, comprises a processor, an output device (often a wireless transceiver), and at least one accelerometer, angle, location, direction, or physiological state sensor. The processor may be configured for various functions, such as analyzing habitual user activities, establishing normal baselines, classifying types of motion and reporting, and logging sensor readings or analysis results. Various algorithms may be used to determine when significant deviations from baseline values occur, and, depending on the type of deviation, the output device can transmit data and alerts. In some embodiments, the data and alerts may be further analyzed by other computerized devices such as mobile phones (smartphones), computers, internet servers, and the like.

The running of a program, designed to train the user to control one or more aspects of his or her psycho-physiological state, is controlled by signals representative of a psycho-physiological parameter of the user, e.g., galvanic skin resistance. This may be detected by a sensor unit with two contacts on adjacent fingers of a user. The sensor unit is separate from a receiver unit which is connected to a computer running the program.

Methods and devices that are capable of measuring physiological parameters of at least two contact points and determining whether the measured parameters reflect favorable or unfavorable physiological responses are disclosed herein. Specifically, the present invention encompasses a method that can non-invasively monitor physiological parameters of at least two contact points before and after a stimulus is applied to a subject and compare the measured parameters to determine whether the physiological state of the subject is favorable or unfavorable.

Monitoring the physiologic status of a human or animal subject includes detecting a blood vessel signal with a sensor. A physiologic time interval can be determined, and information related to the physiologic status of the subject can be analyzed and communicated.

A method and device for delivering and monitoring baroreflex and drug therapy to manage hypertension. The method includes providing an implanted an implanted medical device configured to automatically detect drug-related effects on the autonomic nervous system including the steps of measuring a physiologic status of the autonomic nervous system at desired intervals, logging the physiologic status of the autonomic nervous system at desired intervals, monitoring the measured and logged physiologic status of the autonomic nervous system for any changes and correlating the changes to a corresponding drug administration time. The device includes an implanted baroreflex activation device capable of administering one or more hypertension treatment drugs including a controller that activates and adjusts therapy delivery, a baroreflex activation therapy delivery device, a drug therapy delivery device and a device that senses physiologic parameters.

Embodiments of the subject invention relate to a method and apparatus for remote evaluation of a subject's emotive and / or physiological state. Embodiments can utilize a device that can be used to determine the emotional and / or physiological state of a subject through the measurement and analysis of vital signs and / or speech. A specific embodiment relates to a device capable of remotely acquiring a subject's physiological and / or acoustic data, and then correlating and analyzing the data to provide an assessment of a subject's emotional and / or physiological state. In a further specific embodiment, the device can acquire such data, correlate and analyze the data, and provide the assessment of the subject's emotional state and / or physiological in real time.

Techniques are described for improved monitoring and control of a patient's physiologic status, such as blood glucose control according to a protocol for use in a patient care unit, such as an intensive care unit. Instructions to medical staff are adapted to factor in variations in responses to protocol recommendations. For example, a patient's physiological data as a result of a blood analysis is submitted as input to a program. An instruction for a medical procedure for the patient in response to the physiological data is automatically provided by the program. A confirmation response that the medical procedure has been accomplished and results of following the medical procedure are requested by the program. The time when the medical procedure was accomplished and the results of following the medical procedure are evaluated by the program to determine whether to adapt a subsequent instruction.

This invention is directed to methods and compositions for diagnosis, prognosis and for determining methods of treatment. The physiological status of cells present in a sample (e.g. clinical sample) can be used in diagnosis or prognosis of a condition (e.g. Chronic Lymphocytic Leukemia), in patient selection for therapy, to monitor treatment and to modify or optimize therapeutic regimens. The physiological status of a cell can be determined by comparing the intracellular status of one or more activation elements (e.g. the phosphorylation status of a signaling molecule) in a cell (e.g. a cancer cell) to that of another cell (e.g. a normal cell). The physiological status of a cell can be further classified by adding one or more modulators (e.g. an inhibitor or activator) to the cell in question. In some embodiments, the invention is directed to methods of determining a phenotypic profile of a population of cells.

Techniques are provided for tracking patient respiration or other physiologic states based upon intracardiac electrogram (IEGM) signals. In one example, respiration patterns are detected based upon cycle-to-cycle changes in morphological features associated with individual cardiac cycles while taking into account different cardiac rhythm types within the patient, such as predominantly paced or predominantly intrinsic rhythm types. Once respiration patterns have been identified, episodes of abnormal respiration, such as apnea, hyperpnea, nocturnal asthma, or the like, may be detected and therapy automatically delivered. In addition, techniques for detecting abnormal respiration using a pattern classifier are described, wherein the pattern classifier is trained while distinguishing the different cardiac rhythm types of the patient.

The invention relates a procedure for the detection of stress state, wherein ambulatory heart beat signal is measured. In the first phase segments are defined from heart beat signal with a chosen rule for segmentation. Then at least one segment describing a physiological state with elevated cardiac activity due to physical workload and / or increased metabolic rate is identified and excluded, if exists, and segments other than the excluded segments are detected for a potential stress state, which is identified using a predetermined rule for the heart beat signal.

The invention is an apparatus and method of biofeedback training for attaining a physiological state optimally consistent with the successful performance of a task, wherein the probability of successfully completing the task is made is inversely proportional to a physiological difference value, computed as the absolute value of the difference between at least one physiological signal optimally consistent with the successful performance of the task and at least one corresponding measured physiological signal of a trainee performing the task. The probability of successfully completing the task is made inversely proportional to the physiological difference value by making one or more measurable physical attributes of the environment in which the task is performed, and upon which completion of the task depends, vary in inverse proportion to the physiological difference value.