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239 results about "Physiological responses" patented technology

Physiological Responses. A physiological response is defined as ‘the body’s physical mechanisms that respond when an injury takes place. These are initiated to repair and protect the damaged tissue’. Put into simpler terms, it is how your body reacts when something occurs to cause injury.

Miniaturized cell array methods and apparatus for cell-based screening

The present invention discloses devices and methods of performing high throughput screening of the physiological response of cells to biologically active compounds and methods of combining high-throughput with high-content spatial information at the cellular and subcellular level as well as temporal information about changes in physiological, biochemical and molecular activities. The present invention allows multiple types of cell interactions to be studied simultaneously by combining multicolor luminescence reading, microfluidic delivery, and environmental control of living cells in non-uniform micro-patterned arrays.
Owner:CELLOMICS

Body sign dynamically monitoring system

InactiveUS20110288379A1Reduce hospitalizationReduce mortality rateElectroencephalographyElectrocardiographyNODALComputer module
A real-time body status monitoring system (RBMS) is presented in this invention. A wearable monitoring apparatus (WMA) worn by users consists of one or a few sensor nodes and a computing module. Sensor nodes communicate with the computing module via either wired or wireless protocols. RBMS incorporates a monitoring center that connects and serves many WMAs. Together with the sensors and context-aware information fusion and analysis, the system in the invention goes beyond sampling rare events that may be of profound diagnostic, prognostic, or therapeutic importance. It measures the physiological responses to therapeutic interventions during daily activities, which constitute direct and practical health indicators for the patient.
Owner:WUXI MICROSENS

Systems and methods for displaying changes in biological responses to therapy

Systems and methods of this invention display data using pixels with information indicated by color and intensity changes, particularly used for monitoring of physiological variables in real time. For certain methods, physiological data can be acquired by sensors, acquired data can be stored in data frames, data frames can be processed using computer-implemented methods, and processed data frames can be scaled to a display frame for display on a display device. Using such methods, a spot made up of a group of pixels can be updated during a time frame, or cycle using a computer-implemented method, such as addition, subtraction, multiplication, division or a time dependent function. Newly received data can be combined with prior received data to indicate time-dependent changes. In this way, each spot contains a cumulative history of data starting at some initial time. In other embodiments, visual contrast can be enhanced between desired data and other data. In further embodiments, two or more different types of data can be plotted together to indicate relationships between variables. Real time monitoring of signals during therapeutic treatment using light, electricity or other nerve or muscle stimuli can allow a user to monitor physiological responses during stimulation and to make rapid decisions about medical treatment.
Owner:PHOTOMED TECH

Indirect measurement of tissue analytes through tissue properties

Methods and system for noninvasive determination of tissue analytes utilize tissue properties as reflected in key features of an analytical signal to improve measurement accuracy and precision. Physiological conditions such as changes in water distribution among tissue compartments lead to complex alterations in the measured analytical signal of skin, leading to a biased noninvasive analyte measurement. Changes in the tissue properties are detected by identifying key features in the analytical signal responsive to physiological variations. Conditions not conducive to the noninvasive measurement are detected. Noninvasive measurements that are biased by physiological changes in tissue are compensated. In an alternate embodiment, the analyte is measured indirectly based on natural physiological response of tissue to changes in analyte concentration. A system capable of such measurements is provided.
Owner:GLT ACQUISITION +1

Method and system for using coherence of biological responses as a measure of performance of a media

Various embodiments of the present invention create a novel system for rating an event in a media based on the strength of the emotions viewers feel towards the event. The viewer's responses to the media can be measured and calculated via physiological sensors. The metric for rating the strength of the media is created based on the mathematical coherence of change (up or down) of all pertinent physiological responses across multiple viewers. Such rating offers an objective ability to compare the strengths of events of the media, as there is a strong correlation between high coherence of physiological responses (all viewers feel the same thing at the same time) and strong ratings of emotionality, engagement, likeability, success in the marketplace / on screen.
Owner:NIELSEN CONSUMER LLC

Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

A non-invasive electrical stimulation device shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in which the electrode(s) are in contact. The stimulation device is configured to produce a peak pulse voltage that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie between the vicinity of the target nerve and patient's skin. Current is passed through the electrodes in bursts of preferably five sinusoidal pulses, wherein each pulse within a burst has a duration of preferably 200 microseconds, and bursts repeat at preferably at 15-50 bursts per second.
Owner:ELECTROCORE

Method and system for rating media and events in media based on physiological data

Various embodiments of the present invention enable a bottom up analysis approach that derives physiological responses from measured physiological data of viewers of a media, and calculates scores of instances of an event type based on the physiological responses. The scores are then aggregated to rate the event type in addition to scoring the individual event instances. The approach can also form an overall rating of the media by aggregating the event ratings of set of event types within the media.
Owner:NIELSEN CONSUMER LLC

Controlling neuromodulation using stimulus modalities

InactiveUS7801601B2Head electrodesMagnetotherapyStimulus modalityPhysical therapy
A method, apparatus, and system for affecting neuromodulation based upon an evoking signal applied to a patient's body. An internal and / or external evoking and / or therapeutic signal is applied to a first target portion of a patient's body. Data relating to a physiological response resulting from the internal and / or external evoking and / or therapeutic signal is received. A neurotransmission characteristic of the patient's body is determined based upon the data relating to the physiological response. At least one parameter defining an electrical therapeutic signal provided by an implantable medical device is controlled based upon the determined neurotransmission characteristic to treat a disorder.
Owner:LIVANOVA USA INC

Identification of emotional states using physiological responses

ActiveUS20080221401A1Eliminates potentially confounding factorEliminates potentially confounding factors associatedLocal control/monitoringMedical automated diagnosisEngineeringMood state
The invention provides a method for automatically identifying emotional states of a person in real-time based on physiological responses by exposing a person to a stimulus, measuring the person's physiological response to the stimulus, and comparing the measured physiological response to a known baseline physiological. The deviation of the measured physiological response from the baseline physiological response is determinative of the emotional state.
Owner:ADIDAS

Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses

Systems and methods for treating neuro-psychiatric disorders, such as depression or schizophrenia, and / or other illnesses are disclosed. A patient is diagnosed with a particular neuro-psychiatric disorder or other illness. An electric nerve stimulation (ENS) technique, such as vagus nerve stimulation (VNS), is administered to the patient in conjunction with a magnetic nerve stimulation (MNS) technique. The magnetic nerve stimulation (MNS) technique includes applying a magnetic field to a pre-selected synaptic region of a brain of the patient based on the diagnosis. A physiological response of the brain, such as electroencephalogram (EEG) activity, is monitored. One or more parameters of the magnetic field may be selectively adapted in response to the monitored physiological response. The administration of the ENS technique and the MNS technique may be performed simultaneously, in serial order, or in alternating order depending on the diagnosis.
Owner:ZABARA JACOB

Evaluating therapeutic stimulation electrode configurations based on physiological responses

A medical system comprises a plurality of electrodes; at least one sensor configured to output at least one signal based on at least one physiological parameter of a patient; and a processor. The processor is configured to control delivery of stimulation to the patient using a plurality of electrode configurations. Each of the electrode configurations comprises at least one of the plurality of electrodes. For each of the electrode configurations, the processor is configured to determine a first response of target tissue to the stimulation based on the signals, and a second response of non-target tissue to the stimulation based on the signals. The processor is also configured to select at least one of the electrode configurations for delivery of stimulation to the patient based on the first and second responses for the electrode configurations. As examples, the target tissue may be a left ventricle or vagus nerve.
Owner:MEDTRONIC INC

Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

A non-invasive electrical stimulator shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in contact with the electrodes. The conducting medium is also in contact with an interface element that may conform to the contour of a target body surface of the patient when the interface element is applied to that surface. When the interface element is made of insulating (dielectric) material, and disclosed stimulation waveforms are used, the power source need not supply high voltage, in order to capacitively stimulate the target nerve. The stimulator is configured to produce a peak pulse that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie in the vicinity of the target nerve and patient's skin.
Owner:ELECTROCORE

Methods and devices for analyzing and comparing physiological parameter measurements

Methods and devices that are capable of measuring physiological parameters of at least two contact points and determining whether the measured parameters reflect favorable or unfavorable physiological responses are disclosed herein. Specifically, the present invention encompasses a method that can non-invasively monitor physiological parameters of at least two contact points before and after a stimulus is applied to a subject and compare the measured parameters to determine whether the physiological state of the subject is favorable or unfavorable.
Owner:ZYTO CORP

System and method for controlling electronic devices

A system of the present invention automatically controls electronic devices based on physiological conditions of a user. In this regard, the system includes a sensor and a controller. The sensor is positioned adjacent to an eye of a user and is configured to detect a physiological response of the user. The sensor is configured to transmit, in response to a detection of the physiological response, a signal indicative of the response. The controller is configured to receive the signal and to control an electronic device based on the signal.
Owner:HEWLETT PACKARD DEV CO LP

Devices and methods for non-invasive capacitive electrical stimulation and their use for vagus nerve stimulation on the neck of a patient

A non-invasive electrical stimulation device shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in which the electrode(s) are in contact. The stimulation device is configured to produce a peak pulse voltage that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie between the vicinity of the target nerve and patient's skin. Current is passed through the electrodes in bursts of preferably five sinusoidal pulses, wherein each pulse within a burst has a duration of preferably 200 microseconds, and bursts repeat at preferably at 15-50 bursts per second.
Owner:ELECTROCORE

Method And System For Creating An Aggregated View Of User Response Over Time-Variant Media Using Physiological Data

A novel approach enables comparing and aggregating physiological responses from viewers to a time-variant media. This approach defines key events in the media, measures physiological response to and timing of each of the key events for each viewer of the media, aggregates such response for each key event, reconnects these events in the order they occur, and creates a “profile” of the piece of media. This profile can then be used to accurately gauge the responses from the viewers as when the viewers are engaged in the media and when they are not engaged. Subsequently, such profile can be used to define what needs to be changed in the media to generate the desired responses from the viewers.
Owner:NIELSEN CONSUMER LLC

Stimulation therapy for bladder dysfunction

ActiveUS8989861B2Reduce stimulus intensityDecrease in frequency of bladder contractionElectromyographySensorsPhysical therapyElectrical stimulations
A medical system may include a control module and a therapy delivery module configured to generate and deliver electrical stimulation therapy to a patient. The control module may be configured to control the therapy delivery module to deliver electrical stimulation at a first stimulation intensity for a first time period, to deliver electrical stimulation at a second stimulation intensity for a second time period immediately following the first time period, and to deliver electrical stimulation at the first stimulation intensity for a third time period immediately following the second time period. The second stimulation intensity may be less than the first stimulation intensity. The electrical stimulation may elicit a first inhibitory physiological response during the first time period and a second inhibitory physiological response during the second time period. The second inhibitory physiological response may be greater than the first inhibitory physiological response.
Owner:MEDTRONIC INC

Emotion feedback based training and personalization system for aiding user performance in interactive presentations

The present invention relates to a system and method for implementing an assistive emotional companion for a user, wherein the system is designed for capturing emotional as well as performance feedback of a participant participating in an interactive session either with a system or with a presenter participant and utilizing such feedback to adaptively customize subsequent parts of the interactive session in an iterative manner. The interactive presentation can either be a live person talking and / or presenting in person, or a streaming video in an interactive chat session, and an interactive session can be a video gaming activity, an interactive simulation, an entertainment software, an adaptive education training system, or the like. The physiological responses measured will be a combination of facial expression analysis, and voice expression analysis. Optionally, other signals such as camera based heart rate and / or touch based skin conductance may be included in certain embodiments.
Owner:KOTHURI RAVIKANTH V

Method and apparatus for using biometric data for a customer to improve upsale and cross-sale of items

A computer implemented method, apparatus, and computer usable program code for generating customized marketing messages to increase purchases by a customer. In one embodiment, an item selected by the customer is identified to form a selected item. Biometric readings for the customer are received from a set of biometric devices associated with a retail facility to form the biometric data. The biometric data is data regarding a set of physiological responses of the customer. A set of items is selected from a list of items associated with the selected item using the biometric data for the customer to form a set of promoted items. A customized marketing message for the customer is generated using a set of personalized marketing message criteria for the customer. The customized marketing message comprises a marketing message for the set of promoted items.
Owner:TERRACE LICENSING LLC

System and method for controlling electronic devices

A system of the present invention automatically controls electronic devices based on physiological conditions of a user. In this regard, the system includes a sensor and a controller. The sensor is positioned adjacent to an eye of a user and is configured to detect a physiological response of the user. The sensor is configured to transmit, in response to a detection of the physiological response, a signal indicative of the response. The controller is configured to receive the signal and to control an electronic device based on the signal.
Owner:HEWLETT PACKARD DEV CO LP

Device and methods for non-invasive electrical stimulation and their use for vagal nerve stimulation

A non-invasive electrical stimulation device shapes an elongated electric field of effect that can be oriented parallel to a long nerve, such as a vagus nerve in a patient's neck, producing a desired physiological response in the patient. The stimulator comprises a source of electrical power, at least one electrode and a continuous electrically conducting medium in which the electrode(s) are in contact. The stimulation device is configured to produce a peak pulse voltage that is sufficient to produce a physiologically effective electric field in the vicinity of a target nerve, but not to substantially stimulate other nerves and muscles that lie between the vicinity of the target nerve and patient's skin. Current is passed through the electrodes in bursts of preferably five sinusoidal pulses, wherein each pulse within a burst has a duration of preferably 200 microseconds, and bursts repeat at preferably at 15-50 bursts per second.
Owner:ELECTROCORE

Visual-servoing optical microscopy

The present invention provides methods and devices for the knowledge-based discovery and optimization of differences between cell types. In particular, the present invention provides visual servoing optical microscopy, as well as analysis methods. The present invention provides means for the close monitoring of hundreds of individual, living cells over time; quantification of dynamic physiological responses in multiple channels; real-time digital image segmentation and analysis; intelligent, repetitive computer-applied cell stress and cell stimulation; and the ability to return to the same field of cells for long-term studies and observation. The present invention further provides means to optimize culture conditions for specific subpopulations of cells.
Owner:RGT UNIV OF CALIFORNIA
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