17 results about "Phrenic nerve" patented technology

The present application relates to a kind of respiratory synchronous diaphragm nerve electric stimulator in vitro, belong to medical equipment technical field.The technical scheme of a kind of diaphragm nerve electric stimulation based on real-time breathing signal synchronization trigger is proposed for the problems of high weaning failure rate and quality of life decline caused by VIDD.The technical scheme points include: detecting inspiration negative pressure signal through nasal cavity air pressure sampling tube, control unit dynamically adjusts trigger threshold according to negative pressure signal, when negative pressure is lower than preset value and waveform slope meets the standard, trigger electric stimulation module to output biphasic pulse, pulse parameters include positive and negative alternating waveform, width 0.1ms to 1ms, frequency 10Hz to 50Hz and current intensity 5mA to 30mA, and strictly limit electric stimulation to be only output in inspiration cycle, and expiration cycle is completely blocked stimulation by hardware switch circuit.It is mainly suitable for intensive care and rehabilitation therapy scene, effectively prevent and treat VIDD, improve patient weaning success rate and quality of life.

A device includes at least one first element in operative relation to at least one target tissue from a set of target tissues to treat sleep disordered breathing, which may include obstructive sleep apnea. The operative relation may include sensing and / or stimulation. The at least one target tissue may comprise diaphragm-related tissue, respiratory tissue-related nerves, and / or upper airway patency-related tissue. Example tissue in the set of target tissues includes hypoglossal nerve, infrahyoid muscle (IHM)-innervating nerve, IHMs, glossopharyngeal nerve, an internal superior laryngeal (iSL) nerve, phrenic nerve, diaphragm, pudendal nerve, among other nerves and muscles. In some example, multiple target tissue may be selected for stimulation and / or sensing.

Examples of the disclosure include a system for treating disordered breathing in a patient, including an electrical-pulse generator (IPG) to generate an electrical stimulation and including a controller and a power source, a lead including a first sensor, and a second sensor, the controller being configured to provide, via the lead, first electrical stimulation to a target nerve including a phrenic nerve, receive, from the lead, respiratory information indicative of a respiratory parameter of the patient, determine, based on the respiratory information, a therapy-specific indicator indicative of an effect of the stimulation, receive, from the at least one second sensor, non-respiratory information, determine, based on the non-respiratory information, a patient-specific indicator relating to at least one patient condition, modify, based on at least one of the indicators, at least one parameter of the stimulation, and provide, via the lead, at least one second electrical stimulation having the modified parameter.

The utility model relates to a multifunctional catheter for superior vena cava triggering focus mapping and phrenic nerve pace-making, which comprises a catheter body and a spiral electrode tip arranged at the far end of the catheter body, and a plurality of pace-making electrode groups are arranged on the spiral electrode tip. The catheter body and the spiral electrode tip are telescopically arranged in the sheath and can extend out of the open end of the sheath; the spiral electrode tip is in a contraction configuration in the sheath, and can be converted to an expansion configuration when extending out of the sheath and extending into a phrenic nerve pace-making area in the superior vena cava; the starting end of the spiral electrode tip is connected with a center mapping catheter coaxial with the catheter body, and a plurality of mapping electrode sets are arranged on the center mapping catheter. Compared with the prior art, the multifunctional catheter has the advantages that the spiral electrode tip can be stably attached to the inner wall of the superior vena cava, and the multifunctional catheter can be matched with a central mapping catheter to map a superior vena cava trigger range while playing a pace-making role.

A system for electrical ventilation stimulation of a patient including an implantable nerve stimulator including a stimulation circuit and a pulse generator that produces biphasic charge-balanced pulses to stimulate a phrenic nerve, an external digital programming device having near field communication transmission and a digital interface, and wherein the external digital programming device is used to control settings of the implantable nerve stimulator.

An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic nerve through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

The invention is entitled "Detecting and mapping phrenic nerve through pacing." The invention relates to an apparatus comprising an interface and a processor. The interface is configured to receive one or more magnetic localization signals from one or more position sensors coupled to one or more body surface patches attached to a body of a patient, the magnetic localization signals being indicative of respective positions of the position sensors. The processor is configured to (i) detect an unintentional stimulation of a phrenic nerve of the patient, the unintentional stimulation occurring due to cardiac pacing applied by an intracardiac electrode in a heart of the patient, (ii) estimate, based on the magnetic localization signals, a motion of one or more of the body surface patches occurring during the detected stimulation of the phrenic nerve, (iii) estimate, based on the estimated motion of the body surface patches, a distance between the pacing electrode and the phrenic nerve, and (iv) send an output derived from the estimated distance to an output device.

The invention provides a system and method for improving sleep breathing disorder based on nerve stimulation, and belongs to the technical field of medical treatment. Comprising a mask for collecting nasopharyngeal airflow, snore and vibration signals; the nerve stimulation module is used for stimulating hypoglossal nerves and phrenic nerves through electric pulses; the fixed flow positive pressure support module is used for providing continuous positive airway pressure ventilation; the multi-source data acquisition module is used for acquiring respiratory movement amplitude data and blood oxygen saturation data; the control unit module comprises a data processing core and a double-closed-loop controller; the data processing core is used for identifying a respiratory event type based on an LSTM model and establishing a stimulation-ventilation response relation matrix; the double-closed-loop controller is used for adjusting the stimulation intensity of the nerve stimulation module in real time. By dynamically adjusting parameters, reducing sequential control errors and realizing multi-signal synchronization, the limitation of single nerve stimulation is effectively solved, and the accuracy and effectiveness of intervention are ensured.

The application discloses a kind of respiratory synchronous extracorporeal diaphragm nerve electric stimulator, belong to medical equipment technical field, to solve the problem of low diaphragm muscle contraction efficiency and patient discomfort caused by electric stimulation and patient inhalation action asynchronization in respirator treatment.The device detects the inspiratory flow rate signal in real time by accessing the flow rate sensor at the patient end of the respirator circuit, and transmits it to the control unit after amplification and filtering by the signal conditioning circuit;The control unit determines whether the inspiratory flow rate meets the standard based on the preset threshold, and synchronously triggers the electric stimulation module to output pulse signals matching the respirator inspiration cycle to the diaphragm nerve.The core of its technical scheme includes dynamic detection of flow rate signal, threshold determination logic and adaptive adjustment of electric stimulation pulse envelope length, to ensure that electric stimulation is accurately synchronized with the inspiration phase.The device is mainly used to assist respirator users in enhancing diaphragm nerve driving ability and improving ventilation and blood flow ratio imbalance, and is suitable for rehabilitation treatment of patients with chronic respiratory failure or diaphragm dysfunction.

A pleural catheter device (10) includes: a catheter (20) that drains pleural effusion of a subject; an electrode (22) that is provided to the catheter (20) and applies electrical stimulation to a respiratory muscle or a phrenic nerve of the subject; and a controller (32) that performs control of the electrical stimulation by the electrode (22).

Examples include a treatment system for providing disordered breathing therapy to a sleeping patient, the system comprising at least one first stimulation lead, at least one second stimulation lead, and an implanted therapy controller configured to couple to the leads and to provide at least one phrenic-nerve electrical stimulation to a phrenic nerve of a patient via the at least one first stimulation lead, provide at least one hypoglossal-nerve electrical stimulation to a hypoglossal nerve of the patient via the at least one second stimulation lead, and coordinate a relative timing of the electrical stimulation to the hypoglossal nerve with the electrical stimulation to the phrenic nerve of the patient.

A system and methods for stimulating two or more nerves to treat obstructive sleep apnea includes an implantable nerve stimulator (e.g., an implantable pulse generator) with a single current source for generating a time-multiplexed signal. The time-multiplexed signal includes first pulses defined interleaved with second pulses. The first and second pulses are defined by respective sets of pulse parameters stored in memory. The processor controls at least one switch to selectively steer each first pulse to a first nerve and each second pulse to a second nerve. In some examples, the first and second nerves are selected from a group of nerves consisting of the ansa cervicalis, the phrenic nerve, and the hypoglossal nerve.

Examples of the disclosure include a system for treating disordered breathing in a patient, including an electrical-pulse generator (IPG) to generate an electrical stimulation and including a controller and a power source, a lead including a first sensor, and a second sensor, the controller being configured to provide, via the lead, first electrical stimulation to a target nerve including a phrenic nerve, receive, from the lead, respiratory information indicative of a respiratory parameter of the patient, determine, based on the respiratory information, a therapy-specific indicator indicative of an effect of the stimulation, receive, from the at least one second sensor, non-respiratory information, determine, based on the non-respiratory information, a patient-specific indicator relating to at least one patient condition, modify, based on at least one of the indicators, at least one parameter of the stimulation, and provide, via the lead, at least one second electrical stimulation having the modified parameter.

The invention relates to a lung rehabilitation real-time evaluation system based on EIT parameters, and the system comprises a phrenic nerve-abdominal muscle electrical stimulation module which is used for carrying out the electrical stimulation of phrenic nerves and abdominal muscles of a patient; the electrical impedance tomography equipment is used for monitoring the electrical impedance change of the lung of the patient in real time; the data processing module is used for receiving lung electrical impedance data monitored by the electrical impedance tomography equipment and calculating parameters; the curative effect evaluation module is used for evaluating the lung rehabilitation curative effect according to the calculated parameters; the aging evaluation module is used for evaluating the short-term curative effect and duration of phrenic nerve-abdominal muscle combined electrical stimulation by using EIT parameters; and the early warning module is used for performing early warning according to a set threshold range and a parameter change trend, and performing information feedback on the curative effect module and the aging module according to an early warning level and a real-time state of the patient. The medicine has the advantages that the lung ventilation function of a patient can be effectively improved in the aspect of lung rehabilitation curative effect; in the aspect of lung rehabilitation timeliness, real-time and quantitative evaluation of timeliness characteristics provides a powerful objective tool for accurate implementation and effect evaluation of passive lung rehabilitation.

A respiration promoting apparatus (1) to coordinately stimulate two Phrenic nerves at a neck of a patient for activating a diaphragm of the patient, comprises a first field generator (21), a second field generator (21) and a support structure (3). The first field generator (21) is configured to generate a first spatial field and to be positioned at the patient to stimulate a first Phrenic nerve of the two Phrenic nerves of the patient by means of the first spatial field. The second field generator (22) is configured to generate a second spatial field and to be positioned at the patient to stimulate a second Phrenic nerve of the two Phrenic nerves of the patient by means of the second spatial field. The support structure (3) has an arm holder (33), a first arm (31) and a second arm (32). The first arm (31) and the second arm (32) extend from the arm holder (33). The first field generator (21) is mounted to the first arm (31) and the second field generator (22) is mounted to the second arm (32). The support structure (3) is configured to position the arm holder (33) above or behind a head the patient such that the first arm (31) and the second arm (32) laterally extend along the head towards the neck of the patient.

A stimulation device (10) configured to stimulate the phrenic nerve (220) within the body of a patient (20) includes a coil unit (110) configured to generate a magnetic field (30) and a retainer (120) coupled to the coil unit (110). The retainer (120) is arranged to position the coil unit (110) at the patient's (20) body such that the phrenic nerve (220) can be stimulated by the magnetic field (30) generated by the coil unit (110). The coil unit (110) includes a ferromagnetic core (1110) and a wire (1120) wound around the ferromagnetic core (1110).

A respiration promoting apparatus and a method for promoting respiration for coordinately stimulating two Phrenic nerves of a patient for activating a diaphragm of the patient including a first coil unit and as second coil unit. The first coil unit is configured to be positioned at the patient to stimulate a first Phrenic nerve of the patient. The second coil unit is configured to be positioned at the patient to stimulate a second Phrenic nerve of the patient. The first coil unit has a non-flat first coil winding formed from a conductive elongate component, and the second coil unit also has a non-flat second coil winding formed from a conductive elongate component. A control unit coordinatedly provides current through the first coil winding and the second coil winding such that the first and second Phrenic nerves are stimulated, and a diaphragm of the patient is homogeneously activated.