147 results about "Nerve stimulation" patented technology

A system that can deliver haptic feedback by applying an electrical stimulation to a first area of a user's body to induce a second area of the user's body to experience a level of natural sensation in response to an action occurring in a simulated remote environment and an intensity of the action is described. The system includes a controller to set parameters for the electrical stimulation based on the action occurring in the simulated remote environment and an intensity of the action. The system also includes a signal generator to generate the electrical stimulation comprising the parameters. The system also includes a skin surface electrode placed at a first location on a user's body remote from a second location on the user's body to deliver the electrical stimulation with the parameters to a nerve at or near the first area of the user's body.

The invention discloses a hospital obese patient intelligent weight loss dynamic matching intervention method and decision making system based on multi-modal data fusion, and relates to the field of medical health, and the method comprises the following steps: S1, carrying out the real-time collection and fusion of multi-modal data; s2, dynamic metabolism modeling and plateau period breakthrough; s3, generating a hierarchical intervention strategy; s4, performing psychological-physiological linkage intervention; and S5, performing real-time safety control and feedback optimization. By collecting multi-dimensional data, constructing the model, accurately predicting the metabolic rate, the metabolic plateau period and the sudden eating tendency, dynamically adjusting the exercise intensity and the diet scheme according to the conditions of different patients, triggering a low-intensity exercise mode for the obese patients with cardiac insufficiency and calibrating diet, ensuring the exercise safety, and improving the exercise efficiency. Operation suggestions are generated on the basis of the standard, precise preoperative evaluation is conducted, postoperative rehabilitation is optimized in combination with nerve stimulation data, dangerous postures are monitored, the sport injury risk is reduced, and personalized, safe and efficient intelligent weight reduction intervention for obese patients is achieved.

The invention discloses a wearable fatigue monitoring and feedback method based on deep learning. The method comprises the steps that a heart rate variability signal, a gamma wave band electroencephalogram signal and body movement posture information of a user are collected in real time; denoising, normalizing and synchronously fusing the acquired multi-mode signals; extracting a fatigue state representation vector in real time by adopting a Mamba linear state space sequence model; estimating a user fatigue index in real time based on a lightweight full-connection neural network decoder and constructing an individual fatigue threshold dynamic model; calculating a phase synchronization index of the electroencephalogram signal in real time; and generating and outputting an individualized 40Hz gamma wave band sensory nerve stimulation feedback signal in real time based on the fatigue index and the phase synchronization index. According to the invention, high-robustness fatigue identification and low-delay feedback adjustment in a complex motion noise environment are realized.

The invention provides a nerve stimulation system which comprises a stimulation device, the stimulation device comprises a signal generation circuit, a control module, a signal acquisition circuit and a reuse electrode, and the stimulation device is arranged to be implantable in a body, generates a stimulation signal and applies the stimulation signal to a target nerve through the reuse electrode; the signal generation circuit applies a titration stimulation signal to a target nerve according to a preset mode, the signal intensity of the titration stimulation signal in the preset mode is gradually increased to a peak value from an initial threshold value, and then the titration stimulation signal is generated after the peak value is kept for a period of time or some stimulation periods; gradually reducing to a termination threshold value and ending; when a titration stimulation signal is applied to a target nerve, the signal acquisition circuit can correspondingly acquire an evoked potential; and selecting the stimulation parameter with the lowest stimulation signal intensity in the evoked potential time period meeting the target threshold value as a parameter of a treatment stimulation signal for subsequent treatment stimulation signal application.

A soaking device and methods of using are used to cool and / or to heat a face of a person for a purpose of inducing a desired and / or intended outcome in that person. The cooling and / or the heating of the face may be sufficient to induce the desired and / or the intended outcome in that person. The desired and / or intended outcome may relate to: release of at least one type of neurotransmitter; trigeminal nerve stimulation; (indirect) vagus nerve stimulation; transdermal drug delivery; bypass of the blood-brain-barrier (BBB); aesthetic medicine; cardiovascular; dermatological; ears, nose, and throat (otolaryngological); ophthalmological; neurological; psychological; endocrinological; and / or rheumatological benefits to that person. At least one step of the method may include receiving at least some of the face within an immersion-liquid for at least a minimum amount of time while the immersion-liquid is within a temperature-range and while the immersion-liquid is within the soaking device.

According to the flexible array type external field program control nerve stimulation device, the preparation method and the application thereof, the flexible array type external field program control nerve stimulation device comprises a flexible substrate layer and a stimulation response fiber array layer, and the stimulation response fiber array layer is prepared from a functional material capable of converting external field energy such as ultrasound, magnetism and light into electric energy; the flexible substrate layer with high flexibility is adopted, so that the flexible substrate layer can be matched with the surface of a nerve target tissue in a conformal manner; the stimulation response fiber array layer integrated on the flexible substrate layer in an array arrangement mode can meet the stimulation spatial resolution of neuron and even sub-neuron precision, has the characteristics of excellent flexibility, biocompatibility, passivity and wireless performance, can provide nerve electrical stimulation signals with high spatial resolution, and can be applied to the field of nerve electrical stimulation. The high-resolution nerve electrical stimulation device can be in conformal fit with the irregular surface of nerve soft tissue, and is suitable for high-resolution nerve electrical stimulation of different parts such as eyes, the brain and peripheral nerves.

The invention discloses a system and method for performing cranial nerve stimulation based on olfaction, hearing and synchronous magnetomotive stimulation, and the system comprises a magnetic therapy bearing main body which is a magnetic therapy helmet, serves as a basic bearing structure of the system, and is used for installing all functional assemblies, providing magnetic therapy physical auxiliary stimulation, and achieving the cooperation of magnetic therapy and multi-mode stimulation; the olfactory stimulation subsystem is used for providing olfactory stimulation with precise regulation and control; the auditory stimulation subsystem is used for providing personalized audio stimulation; the magnetomotive stimulation subsystem is used for providing magnetomotive stimulation; the nerve stimulation cooperation subsystem is used for planning multi-mode stimulation as a whole and achieving regulation and control. Through the synergistic effect of olfactory stimulation, auditory stimulation and magnetomotive stimulation, three major neural pathways of olfactory, auditory and somatosensory can be activated at the same time, multi-dimensional nerve resonance is formed, the brain wave synchronization degree is remarkably improved, and the adjuvant therapy effect on Alzheimer's disease, cognitive impairment and other diseases is superior to that of single-mode stimulation.

The present disclosure provides a method and a system for electrical stimulation based on physiological parameter feedback regulation. The method includes: continuously acquiring action data and corresponding tremor manifestation data in daily activities of a user; calculating an average tremor level of the user based on the tremor manifestations; identifying a plurality of actions exhibiting tremor manifestations deviating from the average tremor level, and constructing an action set; constructing a continuous action sequence based on the action set; and guiding the user to execute the continuous action sequence while respectively applying electrical nerve stimulation with a plurality of candidate stimulation parameter sets, determining a first electrical stimulation parameter set that satisfies the conditions that the tremor level of the Category I actions decreases, and the tremor level of the Category II actions does not rise, and performing subsequent electrical stimulation using the first electrical stimulation parameter set.

The invention discloses a multifunctional neural electrode for intracranial pressure detection and closed-loop nerve regulation, the multifunctional electrode sequentially comprises a PMUT electrode for intracranial pressure detection and nerve regulation and a macro-micro electrode for electroencephalogram signal detection from top to bottom, and the PMUT electrode is bonded on the macro-micro electrode. The PMUT electrode is bonded to the macro-micro electrode to serve as a multifunctional electrode, the PMUT electrode can serve as a pressure sensor and can also serve as an ultrasonic transducer, the dual functions of intracranial pressure detection and fixed-point ultrasonic nerve stimulation are achieved, the macro-micro electrode can achieve detection of local field potential and peak potential, and the ultrasonic nerve stimulation function is achieved. Therefore, a detection-feedback-regulation closed-loop system is realized.

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinson tremor, and other forms of tremor. In one aspect, the stimulation algorithm is designed to optimize the therapy. The algorithm may be a learning algorithm to tailor the stimulation over time to adjust in real-time to a user's tremor user-defined needs. Stimulation can be delivered using open and / or closed loop systems.

The utility model relates to the technical field of nerve stimulation, and discloses an electrode contact, an implantable electrode and a nerve stimulation system. The electrode contact comprises a plurality of contact surfaces, each contact surface can independently serve as a stimulation source, and at least two contact surfaces in the plurality of contact surfaces face different directions, so that the electrode contact has a plurality of stimulation directions. According to the electrode contact scheme provided by the embodiment of the utility model, more stimulation directions can be provided, and the effectiveness and accuracy of nerve stimulation can be improved.

The invention discloses a closed-loop vagus nerve stimulation system capable of cooperating with rehabilitation exercise. The closed-loop controller is used for collecting an external signal related to animal movement as a gating signal, processing the signal and generating a control instruction; the vagus nerve stimulator is used for receiving the control instruction of the closed-loop controller, adjusting stimulation parameters and outputting vagus nerve stimulation pulses; the wireless communication module is used for realizing wireless connection between the closed-loop controller and the vagus nerve stimulator and ensuring rapid transmission of a control instruction; the motion signal acquisition device is used for acquiring external signals related to animal motion; according to the invention, the problem of output misalignment of existing small equipment under a high load is obviously improved through a four-stage cascaded constant-current pulse generation architecture; meanwhile, based on a naked pulse infrared direct drive protocol and an MCU highly integrated processing chain, the timing sequence matching precision requirement of vagus nerve stimulation pulses and rat rehabilitation exercise actions is ensured.

Systems, devices, and methods for stimulating peripheral nerves in the fingers or hand to treat tremor are described. For example, a wearable ring device for delivering electrical stimulation to sensory nerves in a patient's finger can include an annular ring having a plurality of electrodes and a detachable unit having a power source and a pulse generator.

A Peripheral Nerve Stimulation (PNS) system and method are disclosed. The system includes a headset with ear hooks and electrodes for placement on the mastoid processes. A stimulation device connected to the headset via lead wires delivers a pulsed electrical current to the electrodes. The device communicates with a computing device equipped with a mobile application that controls the stimulation characteristics. The mobile application allows users to adjust settings, monitor progress, and access treatment sessions. The system also includes snap ports for electrode attachment, self-adhesive hydrogel electrodes, and current control mechanisms using a digital potentiometer and waveform generator. The method includes pre- and post-session anxiety rating, personalized treatment based on user inputs, and tracking of physiological biomarkers. The application supports multiple operating systems, secure cloud data storage, and enables data sharing with healthcare providers. The invention provides a comprehensive, customizable, safe solution for managing anxiety and insomnia.

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinsonian tremor, and other forms of tremor. The stimulator may be inductively charged in certain aspects. The stimulation device can be configured to be worn on the wrist of a user.

The invention discloses a portable muscle relaxation monitoring device, and relates to the technical field of medical instruments, the portable muscle relaxation monitoring device comprises a muscle relaxation monitor and a display screen, and the portable muscle relaxation monitoring device further comprises a storage assembly arranged on the muscle relaxation monitor and used for storing a circuit into the muscle relaxation monitor; wherein the storage assembly comprises a cavity, the cavity is arranged in the muscle relaxation monitor, the interior of the cavity is connected with a connector lug through a wire, the end part of the connector lug is connected with a nerve stimulation line, the interior of the cavity is slidably connected with a movable rod, the top end of the movable rod penetrates through the cavity and is connected with a limiting rod, and the limiting rod is connected with the connector lug. A second sliding groove is formed in the display screen, an extrusion part is connected to the bottom end of a movable rod, a connecting frame is hinged to one side of the extrusion part, and a second movable plate and a connector lug are driven to move through the movable rod, so that a nerve stimulation line can be shrunk into a cavity, and the space occupied by the line is reduced; and lines can be prevented from intertwining, and carrying is convenient.

Examples of the disclosure include an implantable system comprising principal stimulation circuitry configured to provide electrical stimulation to a phrenic nerve via at least one phrenic nerve stimulation electrode, subordinate stimulation circuitry configured to provide electrical stimulation to an upper-airway nerve via at least one upper-airway-nerve stimulation electrode, at least one respiration sensor, and an implantable pulse generator (IPG) comprising the stimulation circuitries and at least one processor configured to cause the subordinate stimulation circuitry to deliver stimulation in an absence of delivery of the phrenic nerve stimulation, monitor a signal from the respiration sensor(s), identify a respiration reduction based on the signal during the stimulation delivery, and in response thereto, cause the stimulation circuitries to deliver the stimulations concurrently based in part on the respiration signal and control a timing of delivery of the upper- airway-nerve electrical stimulation relative to a timing of delivery of the phrenic nerve electrical stimulation.

The invention provides an implantable pulse generator which is used for a small implantable nerve stimulation system and is suitable for receiving and fixing a stimulation electrode. The implantable pulse generator comprises a main body and a locking assembly. The body has a stimulating electrode receiving aperture and a locking aperture. The locking assembly is configured to pass through the locking hole and fix the stimulating electrode. The locking assembly comprises a locking bolt and a first sealing ferrule. The locking bolt is composed of a locking bolt head part and a locking bolt rod part in the first direction. The diameter of the locking bolt head part is larger than that of the locking bolt rod part. The locking bolt rod part penetrates through the locking hole and enters the stimulating electrode receiving hole to abut against the stimulating electrode. By providing a locking bolt having a head such that a first sealing ferrule may be added between the head and the body, the sealing interface avoids the possibility of thread breakage. As the rod part of the locking bolt extends into the locking hole, the first sealing ferrule is extruded, and the sealing effect is improved.

The invention relates to the field of medical equipment, in particular to a neck nerve stimulator, a neck nerve stimulation method and a computer readable storage medium, and the neck nerve stimulator comprises a position sensing unit which is used for obtaining neck position information; the energy output unit is used for outputting stimulation energy; the control unit is connected with the position sensing unit and the energy output unit and is used for determining the position of a neck nerve according to the neck position information output by the position sensing unit; the control unit is further used for controlling the energy output unit to output stimulation energy at the position where the neck nerves are located. Accurate positioning and precise stimulation of the neck nerves are achieved, and a common user can use the device conveniently.

A method of implanting a nerve stimulation device in treating an overactive bladder condition includes providing an external programmer and providing an implantable tibial nerve stimulation device (ITNS device) including a pulse generator enclosing circuitry and a lead coupling an electrode assembly to the pulse generator. The external programmer wirelessly communicates with the circuitry of the pulse generator to program a stimulation therapy for the ITNS device.

The present disclosure may include an electroceutical configured to sense a signal generated from a nerve and provide stimulation to the nerve, and an electronic device configured to control the electroceutical. The present disclosure relates to a system having an electroceutical for nerve stimulation, the electroceutical including a plurality of lead wires disposed to surround the nerve, a header connector including a plurality of pins connected to the plurality of lead wires; and a microcontroller unit (MCU) configured to change a setting of the header connector based on a control signal received from the electronic device.

The embodiment of the invention discloses a testing device. The testing device comprises a cable, a connecting assembly and a stimulating assembly which are connected in sequence. Wherein the connecting assembly is provided with a limiting groove for limiting and fixing the implantable electrode, a plurality of conductive elastic sheets in conductive connection with the cable are arranged in the limiting groove, and the conductive elastic sheets are used for being detachably and electrically connected with a wire of the implantable electrode, so that the implanted implantable electrode is tested. The stimulation assembly is provided with a conductive probe electrically connected with the cable, and can apply a test electric signal to the nervous tissue to carry out a stimulation reaction test, thereby assisting in accurately confirming the position of the target spot. According to the testing device, the electrode testing function and the nerve stimulation testing function are integrated into a single device, the structure is compact, operation is visual, and the accuracy, smoothness and convenience of an operation are remarkably improved.

A nerve stimulation system comprising includes a housing, circuitry that generates an electrical stimulation signal, a microcontroller, one or more leads connected to the circuitry in the housing, and a return electrode electrically coupled to the circuitry, where the return electrode provides an electrical flow path for the stimulation signal from the one or more leads back to the housing. The system also includes a first control device and a second control device that cause the circuitry to generate the stimulation signal over a first channel or the second channel through the one or more leads. The system also includes one or more indicators fixed with the housing and electrically coupled to the microcontroller, where the one or more indicators generate visual indications, audio indications, or haptic indications that vary according to different status conditions of the circuitry on a per channel basis.

The invention relates to the technical field of medical instruments for spinal nerve stimulation, and provides a wireless power supply implantable spinal nerve light regulation and control device, which comprises an in-vitro energy transmitting end and an in-vivo implanted light source, the in-vitro energy transmitting end comprises an energy supply unit, a multi-degree-of-freedom positioning structure and a wireless energy transmitting and working state feedback mechanism; the multi-degree-of-freedom positioning structure drives the wireless energy transmitting and working state feedback mechanism to adjust the pose; the wireless energy emission and working state feedback mechanism provides wireless electromagnetic waves for the in-vivo implanted light source in the body of a patient, the in-vivo implanted light source generates continuous light or pulsed light to conduct light treatment on the spinal cord injury part, and the in-vivo implanted light source emits near-infrared light. And the wireless energy emission and working state feedback mechanism transmits a monitored near-infrared light intensity signal to the degree-of-freedom positioning structure to drive the wireless energy emission and working state feedback mechanism to adjust the pose. Light source stimulation of light biological regulation technical parameters can be met, and light biological regulation treatment is achieved.

An object of the present technology is to provide a nerve stimulation device, a nerve stimulation system, and a nerve stimulation method capable of applying abundant variations of electrical stimulation to a nerve with high accuracy without having wiring between the nerve stimulation device and an external power supply.SOLUTION: The nerve stimulation device includes a power receiving unit 130, a stimulation electrode 150, and a stimulation current generating unit 140 that generates a stimulation current to be applied to the stimulation electrode 150. The power receiving unit 130, the stimulation electrode 150, and the stimulation current generating unit 140 can be implanted in a living body. The stimulation electrode 150 is electrically connected to a nerve in a living body. The stimulation current generating unit 140 has a stimulation current pattern selecting part 143 for selecting a stimulation current pattern based on the change of the frequency when the power receiving unit 130 receives the power, and a stimulation current generating part 144 for generating the stimulation current based on the stimulation current pattern.SELECTED DRAWING: Figure 2

The invention discloses a peripheral nerve plexus stimulation needle capable of automatically locking puncture depth, which relates to the technical field of nerve stimulation needles, and comprises a positioning ring seat used for being positioned above a part to be subjected to needle application; the adsorption assembly is fixedly connected below the positioning ring seat; the depth self-locking assembly is arranged in the positioning ring seat; the telescopic rods are arranged in a circumferential array, one end of each telescopic rod is hinged to the positioning ring seat, and the other end of each telescopic rod is hinged to the depth self-locking assembly; the nerve stimulation needle is arranged in the depth self-locking assembly in a penetrating manner, is driven by the depth self-locking assembly to adjust the needle setting depth, and is locked by the depth self-locking assembly after being adjusted to the target depth; the nerve stimulator is electrically connected with the nerve stimulation needle, the peripheral nerve plexus stimulation needle can achieve multiple self-locking, and the overall safety is improved.

The invention belongs to the field of biomedical engineering, and discloses a function positioning system for connection of a medial thalamic pillow and an emotional cortex, which comprises the following steps of: performing near-infrared nerve stimulation on the medial thalamic pillow, and collecting an MRI (Magnetic Resonance Imaging) structure image and an MRI function image during stimulation; according to the MRI structure image, projecting a buckling back, a brain island, an amygdaloid nucleus and a subregion thereof, and a brain region adjacent to the buckling back, and respectively segmenting the buckling back, the brain island and the amygdaloid nucleus; different body emotion expression function partitions are positioned at the buckle back; positioning the internal sensory function subareas according to the subareas of the brain island; according to different subregions of the amygdala kernel, positioning the emotion function regions of the amygdala kernel; according to the MRI functional image, the activated voxel is evaluated, and according to the positions of the activated voxel in different emotional loop brain areas, the function positioning of the connection of the inner thalamic pillow and the emotional cortex is realized. According to the system, the specific topological connectivity of the inner thalamic pillow and the brain emotional cortex is realized.

Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of consecutive pulse sequences (110), wherein each pulse sequence (110) has a pulse sequence amplitude (111); delivering the electrical stimulation pattern (100) to a nerve (510) of a subject with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein the modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse sequence amplitude (111) from one pulse sequence (110) to consecutive pulse sequences (110) until a determined target stimulation amplitude (130) is reached at a stimulation onset (101); characterized in that the modulation of the electrical stimulation pattern (100) further comprises reducing the target stimulation amplitude (130) to a defined reduction amplitude (140) within each pulse sequence (110) after the target stimulation amplitude (130) is reached.