301 results about "Nerve stimulation" patented technology

Devices and methods for the non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode coupled to the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is coupled to the housing and operably coupled to the electrode. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises burst periods and constant periods, wherein each burst period includes 2 to 20 pulses and has a duration of less than 20,000 microseconds.

The invention discloses a peripheral nerve stimulation system based on muscle fatigue prediction and compensation, which is used for acquiring electromyographic signals and predicting muscle fatigue states during nerve stimulation, and timely warning and adjusting stimulation to ensure the stability of muscle strength, and comprises a stimulation output module used for stimulating target nerves to activate target muscles according to stimulation parameters; the acquisition and analysis module is used for synchronously acquiring electromyographic signals of target muscles, preprocessing the electromyographic signals and extracting electromyographic signal features; the fatigue prediction module is used for predicting the fatigue state of the muscle according to the electromyographic signal characteristics; the compensation control module is used for adjusting stimulation parameters according to the fatigue state of the muscle and sending the stimulation parameters to the stimulation output module to ensure that the muscle strength is stable in the stimulation process; and the user interaction module is used for performing stimulation control and setting in real time and displaying the stimulation effect and the muscle fatigue state. Muscle fatigue and strength attenuation in the peripheral nerve stimulation process can be dynamically predicted and compensated in time, and the safety, accuracy and reliability of nerve stimulation are improved.

The invention relates to the technical field of medical instruments, in particular to a nerve stimulation electrode based on a shape memory material. The nerve stimulation electrode comprises a flexible packaging electrode body and a substrate crease layer arranged on the surface of the flexible packaging electrode body. The material of the substrate crease layer comprises a shape memory polymer and a nano ferromagnetic material; the substrate crease layer comprises a first bending part which is used for enabling the flexible packaging electrode body to be folded along the length direction of the flexible packaging electrode body. The nerve stimulation electrode can solve the problems that an existing nerve stimulation electrode is hard in appearance, large in overall mass, poor in flexibility and complex in implantation operation.

Disclosed herein are systems, devices, and methods for peripheral nerve stimulation, particularly for treating tremor. The nerve stimulation may be accomplished by a wearable nerve stimulation device, such as a band configured to be worn on the wrist or other body part. The device can accomplish targeted nerve stimulation using circumferentially spaced electrodes. In some embodiments, the device may use only the same number of electrodes as the number of nerves that are to be stimulated. A biphasic charge-balanced waveform may be used to selectively stimulate a nerve near one of the activated electrodes but not to stimulate the nerve near the other activated electrode. The device may use dry electrodes for long-term, repeated use. The dry electrodes may include a conductive base layer and a polymeric, plastic or rubber skin contact layer comprising a conductive filler. The filler may be a powder, fiber, conductive coating, etc.

The present disclosure provides an implanted nerve stimulator electrode for an implanted nerve stimulation system, the implanted nerve stimulator electrode being adapted to be at least partially implanted into a human body and receiving an electrical signal from an implanted pulse generator to apply electrical stimulation to the human body. An implanted nerve stimulator electrode includes an elongate body, a plurality of wires, and at least one nerve stimulation contact structure. The nerve stimulation contact structure is in a hollow sleeve shape and is suitable for being arranged on the main body in a sleeving mode. Each nerve stimulation contact structure comprises at least two contacts, and when the nerve stimulation contact structures are arranged on the main body in a sleeving mode, each contact on the nerve stimulation contact structure is electrically connected with one corresponding wire. After the nerve stimulation contact structure provided by the invention is sleeved on the main body, an operator can weld the corresponding wire to the contact under the condition of no shielding or little shielding, so that the welding difficulty from the contact to the wire is reduced. And the production efficiency is improved.

A system that can deliver haptic feedback by applying an electrical stimulation to a first area of a user's body to induce a second area of the user's body to experience a level of natural sensation in response to an action occurring in a simulated remote environment and an intensity of the action is described. The system includes a controller to set parameters for the electrical stimulation based on the action occurring in the simulated remote environment and an intensity of the action. The system also includes a signal generator to generate the electrical stimulation comprising the parameters. The system also includes a skin surface electrode placed at a first location on a user's body remote from a second location on the user's body to deliver the electrical stimulation with the parameters to a nerve at or near the first area of the user's body.

The invention relates to the technical field of medical instruments, and provides electric coagulation forceps with an intraoperative nerve detection function and a control method for the electric coagulation forceps to automatically switch a nerve stimulation function and an electric coagulation function, and the electric coagulation forceps comprise a high-frequency excitation identification circuit, a controller and a nerve monitoring switching circuit. The high-frequency excitation identification circuit is used for generating a corresponding induction signal according to whether the high-frequency excitation signal is detected; the controller generates a first control signal, starts timing and determines target delay time after determining that the electrocoagulation cutting function of the pair of electrocoagulation forceps is converted from an on state to an off state according to the induction signal, and generates a first prompt signal to indicate the prompt device to generate first prompt information after the timing time reaches the target delay time; the user is prompted; the nerve monitoring switching circuit is used for responding to the first control signal and outputting a nerve stimulation signal of the nerve monitor through the forceps tips, so that the nerve tissue damage probability is reduced while automatic function switching is achieved.

The invention discloses a hospital obese patient intelligent weight loss dynamic matching intervention method and decision making system based on multi-modal data fusion, and relates to the field of medical health, and the method comprises the following steps: S1, carrying out the real-time collection and fusion of multi-modal data; s2, dynamic metabolism modeling and plateau period breakthrough; s3, generating a hierarchical intervention strategy; s4, performing psychological-physiological linkage intervention; and S5, performing real-time safety control and feedback optimization. By collecting multi-dimensional data, constructing the model, accurately predicting the metabolic rate, the metabolic plateau period and the sudden eating tendency, dynamically adjusting the exercise intensity and the diet scheme according to the conditions of different patients, triggering a low-intensity exercise mode for the obese patients with cardiac insufficiency and calibrating diet, ensuring the exercise safety, and improving the exercise efficiency. Operation suggestions are generated on the basis of the standard, precise preoperative evaluation is conducted, postoperative rehabilitation is optimized in combination with nerve stimulation data, dangerous postures are monitored, the sport injury risk is reduced, and personalized, safe and efficient intelligent weight reduction intervention for obese patients is achieved.

The invention discloses a wearable fatigue monitoring and feedback method based on deep learning. The method comprises the steps that a heart rate variability signal, a gamma wave band electroencephalogram signal and body movement posture information of a user are collected in real time; denoising, normalizing and synchronously fusing the acquired multi-mode signals; extracting a fatigue state representation vector in real time by adopting a Mamba linear state space sequence model; estimating a user fatigue index in real time based on a lightweight full-connection neural network decoder and constructing an individual fatigue threshold dynamic model; calculating a phase synchronization index of the electroencephalogram signal in real time; and generating and outputting an individualized 40Hz gamma wave band sensory nerve stimulation feedback signal in real time based on the fatigue index and the phase synchronization index. According to the invention, high-robustness fatigue identification and low-delay feedback adjustment in a complex motion noise environment are realized.

The invention provides a nerve stimulation system which comprises a stimulation device, the stimulation device comprises a signal generation circuit, a control module, a signal acquisition circuit and a reuse electrode, and the stimulation device is arranged to be implantable in a body, generates a stimulation signal and applies the stimulation signal to a target nerve through the reuse electrode; the signal generation circuit applies a titration stimulation signal to a target nerve according to a preset mode, the signal intensity of the titration stimulation signal in the preset mode is gradually increased to a peak value from an initial threshold value, and then the titration stimulation signal is generated after the peak value is kept for a period of time or some stimulation periods; gradually reducing to a termination threshold value and ending; when a titration stimulation signal is applied to a target nerve, the signal acquisition circuit can correspondingly acquire an evoked potential; and selecting the stimulation parameter with the lowest stimulation signal intensity in the evoked potential time period meeting the target threshold value as a parameter of a treatment stimulation signal for subsequent treatment stimulation signal application.

The invention belongs to the technical field of medical puncture equipment, and particularly discloses an ultrasound-guided peripheral nerve block anesthesia directional puncture device which comprises a first fixing tube, a connecting plate is arranged on the outer side of the first fixing tube, a first motor is arranged above the connecting plate, and a first rotating shaft is arranged at the output end of the first motor. A first gear is arranged on the outer side of the first rotating shaft, a second gear is arranged on the outer side of the first fixing pipe, a connecting ring is arranged below the second gear, a first connecting frame is arranged below the connecting ring, a second fixing pipe is arranged on the inner side of the first connecting frame, and a first electric telescopic rod is arranged on the inner side of the second fixing pipe. An electrode plate is arranged at one end of the first electric telescopic rod, a third fixing pipe is arranged on the inner side of the first connecting frame, a second electric telescopic rod is arranged on the inner side of the third fixing pipe, and an ultrasonic probe is arranged at one end of the second electric telescopic rod; neural stimulation and ultrasonic guidance are combined, and the problem that tiny nerves are difficult to recognize under ultrasonic guidance is effectively solved.

A soaking device and methods of using are used to cool and / or to heat a face of a person for a purpose of inducing a desired and / or intended outcome in that person. The cooling and / or the heating of the face may be sufficient to induce the desired and / or the intended outcome in that person. The desired and / or intended outcome may relate to: release of at least one type of neurotransmitter; trigeminal nerve stimulation; (indirect) vagus nerve stimulation; transdermal drug delivery; bypass of the blood-brain-barrier (BBB); aesthetic medicine; cardiovascular; dermatological; ears, nose, and throat (otolaryngological); ophthalmological; neurological; psychological; endocrinological; and / or rheumatological benefits to that person. At least one step of the method may include receiving at least some of the face within an immersion-liquid for at least a minimum amount of time while the immersion-liquid is within a temperature-range and while the immersion-liquid is within the soaking device.

According to the flexible array type external field program control nerve stimulation device, the preparation method and the application thereof, the flexible array type external field program control nerve stimulation device comprises a flexible substrate layer and a stimulation response fiber array layer, and the stimulation response fiber array layer is prepared from a functional material capable of converting external field energy such as ultrasound, magnetism and light into electric energy; the flexible substrate layer with high flexibility is adopted, so that the flexible substrate layer can be matched with the surface of a nerve target tissue in a conformal manner; the stimulation response fiber array layer integrated on the flexible substrate layer in an array arrangement mode can meet the stimulation spatial resolution of neuron and even sub-neuron precision, has the characteristics of excellent flexibility, biocompatibility, passivity and wireless performance, can provide nerve electrical stimulation signals with high spatial resolution, and can be applied to the field of nerve electrical stimulation. The high-resolution nerve electrical stimulation device can be in conformal fit with the irregular surface of nerve soft tissue, and is suitable for high-resolution nerve electrical stimulation of different parts such as eyes, the brain and peripheral nerves.

Devices and methods for the non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode coupled to the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is coupled to the housing and operably coupled to the electrode. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises burst periods and constant periods, wherein each burst period includes 2 to 20 pulses and has a duration of less than 20,000 microseconds.

The invention provides an adaptive neuro-regulation sleep optimization system and method, a wearable device and a medium, the adaptive neuro-regulation sleep optimization system comprises: an acquisition module configured to acquire an electroencephalogram signal of a user; the processing module is configured to determine a first nerve stimulation parameter based on the sleep stage where the electroencephalogram signal is located, and determine a second nerve stimulation parameter based on the phase characteristic of the electroencephalogram signal, and based on the first nerve stimulation parameter, the second nerve stimulation parameter and a preset stimulation signal parameter, correspondingly generating and outputting self-adaptive nerve stimulation signals of one or more stimulation types so as to adjust the nerve of the user and optimize sleep. According to the method, the nerve stimulation signal is generated in real time based on the electroencephalogram signal of the user, so that self-adaptive nerve regulation is performed on the user, and targeted sleep optimization can be performed on the user through the nerve stimulation signal.

The invention discloses a system and method for performing cranial nerve stimulation based on olfaction, hearing and synchronous magnetomotive stimulation, and the system comprises a magnetic therapy bearing main body which is a magnetic therapy helmet, serves as a basic bearing structure of the system, and is used for installing all functional assemblies, providing magnetic therapy physical auxiliary stimulation, and achieving the cooperation of magnetic therapy and multi-mode stimulation; the olfactory stimulation subsystem is used for providing olfactory stimulation with precise regulation and control; the auditory stimulation subsystem is used for providing personalized audio stimulation; the magnetomotive stimulation subsystem is used for providing magnetomotive stimulation; the nerve stimulation cooperation subsystem is used for planning multi-mode stimulation as a whole and achieving regulation and control. Through the synergistic effect of olfactory stimulation, auditory stimulation and magnetomotive stimulation, three major neural pathways of olfactory, auditory and somatosensory can be activated at the same time, multi-dimensional nerve resonance is formed, the brain wave synchronization degree is remarkably improved, and the adjuvant therapy effect on Alzheimer's disease, cognitive impairment and other diseases is superior to that of single-mode stimulation.

The present disclosure provides a method and a system for electrical stimulation based on physiological parameter feedback regulation. The method includes: continuously acquiring action data and corresponding tremor manifestation data in daily activities of a user; calculating an average tremor level of the user based on the tremor manifestations; identifying a plurality of actions exhibiting tremor manifestations deviating from the average tremor level, and constructing an action set; constructing a continuous action sequence based on the action set; and guiding the user to execute the continuous action sequence while respectively applying electrical nerve stimulation with a plurality of candidate stimulation parameter sets, determining a first electrical stimulation parameter set that satisfies the conditions that the tremor level of the Category I actions decreases, and the tremor level of the Category II actions does not rise, and performing subsequent electrical stimulation using the first electrical stimulation parameter set.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a light source and a speaker. A visual neural stimulation system provides, via the light source, visual stimulation having a first value of a first parameter. An auditory neural stimulation system provides, via the speaker, audio stimulation having a second value of the second parameter. A stimuli orchestration component selects, for a first time interval, one of the visual stimulation or the audio stimulation to vary based on a policy, selects, for the first time interval, the other of the visual stimulation or the audio stimulation to keep constant based on the policy, and provides causes the one of the visual neural stimulation system or the auditory neural stimulation system to vary the one of the visual stimulation or the audio stimulation.

The invention relates to the technical field of medical equipment, in particular to an implantable nerve stimulation system which comprises a controller, the controller is configured to execute closed-loop stimulation output, judge whether a physiological signal accords with a preset state or not according to the physiological signal, set a plurality of preset states according to priority, and set a corresponding closed-loop stimulation rule for each state, and executing a corresponding adaptive stimulation rule according to the confirmed preset state, and executing a motion adaptive stimulation rule if the system is not in any preset state, thereby realizing more accurate and meticulous closed-loop regulation and control.

Systems and methods of the present disclosure are directed to systems and methods for treating cognitive dysfunction in a subject in need thereof. The system can include a light source and a speaker. A visual neural stimulation system provides, via the light source, visual stimulation having a first value of a first parameter. An auditory neural stimulation system provides, via the speaker, audio stimulation having a second value of the second parameter. A stimuli orchestration component selects, for a first time interval, one of the visual stimulation or the audio stimulation to vary based on a policy, selects, for the first time interval, the other of the visual stimulation or the audio stimulation to keep constant based on the policy, and provides causes the one of the visual neural stimulation system or the auditory neural stimulation system to vary the one of the visual stimulation or the audio stimulation.

The invention discloses an intelligent sacral nerve stimulation system based on six-contact electrode real-time monitoring and positive and negative electrode combination real-time dynamic adjustment, a rehabilitation system and a six-contact electrode sacral nerve stimulation system.The sacral nerve stimulation autonomous adjustment system comprises a six-contact electrode sacral nerve stimulation unit and an adjustment control unit, the six-contact electrode sacral nerve stimulation unit is electrically connected with the adjustment control unit, and the adjustment control unit is used for responding to an adjustment request at the current moment and generating a stimulation signal in a stimulation channel according to the six-contact electrode sacral nerve stimulation unit; in response to the stimulation signal, determining a second neural signal matched with the first neural signal; and outputting an adjustment control instruction according to the second neural signal so as to control the six-contact electrode sacral nerve stimulation unit to autonomously adjust. On one hand, sacral nerve stimulation self-adjustment can be periodically realized, and on the other hand, sacral nerve stimulation accuracy is improved. The invention further provides a rehabilitation system.

A system, device, and method for transcutaneous nerve stimulation such as facial nerve stimulation, and in particular, to using transcutaneous nerve stimulation for artificially eliciting eye blink, such as with humans with acute facial paralysis (Bell's palsy or Dry Eye syndrome), is disclosed. A battery-operated wearable device may employ a pulse generator for periodically and automatically In generating bursts train of asymmetrical Bi-Phasic square pulses. The output pulses are fed to two electrodes that are attached to the skin of the treated person to stimulate the facial nerve for eliciting blinking at a rate that mimics normal blinking operation. The device may include a sensor and a wireless connection, and the parameters of, or the activation of, the generated bursts may be controlled by the sensor output, by human user control, or by data received from the wireless network. Further, the device may transmit status to the wireless network.

The present invention relates to a vagus nerve stimulation device. The vagus nerve stimulation device includes: a stimulation unit including an electrode worn on at least one of the left ear and the right ear to apply electrical stimulation to the vagus nerve of the external ear; a control unit for transmitting, to the stimulation unit, an electrical stimulation signal for generating electrical stimulation; and a mode selection unit through which a user selects a stimulation mode, wherein the mode selection unit includes a plurality of preset modes, each including an electrical stimulation signal that includes a stimulation pattern constituting the frequency of a stimulation pulse and the application type of a stimulation, the control unit stores information on an electrical stimulation signal corresponding to each mode and transmits the electrical stimulation signal corresponding to a mode selected by a user to the stimulation unit, and the mode selection unit includes a tension relaxation mode, a concentration mode, and a sleep induction mode. The present invention has a plurality of operation modes specialized for a specific purpose, thereby improving the effect of electrical stimulation through a mode selected according to the user's use purpose.

The invention relates to an intelligent lower limb rehabilitation system and method based on nerve electrical stimulation and pneumatic cooperative control, and belongs to the technical field of medical rehabilitation instruments. A nerve electrical stimulation module; a multi-sensor sensing module; the control system comprises a data processing unit, a decision-making unit and a communication unit, the data processing unit is used for processing and analyzing signals collected by the multi-sensor sensing module, and the decision-making unit is used for generating nerve electrical stimulation and pneumatic driving control instructions according to a data analysis result; the communication unit is responsible for data communication; a personalized rehabilitation scheme can be formulated according to individual differences and real-time motion states of patients, the motion states and feedback information of the patients are monitored in real time through the multi-sensor sensing module, intelligent monitoring and training scheme adjustment are carried out, the adaptive capacity and training quality and efficiency of the patients are improved, thrombus is effectively prevented, and the rehabilitation effect of the patients is improved. And good news is brought to the patients.

The invention discloses a head-mounted nerve stimulator capable of delaying and improving a cognitive function, and belongs to the technical field of brain nerve stimulation, the head-mounted nerve stimulator comprises a head-mounted earmuff worn on the head of a patient, one side of the middle part of the head-mounted earmuff is provided with an 808nm infrared light therapy device which is used for stimulating the brain of the patient and is adjustable in angle, and the other side of the head-mounted earmuff is provided with an infrared light source. A 40Hz light flickering device used for conducting visual stimulation on eyes of a patient is arranged in the eye protection device, and the device can stimulate the brain of the patient in the modes of 808nm infrared therapy, eye visual stimulation 40Hz light flickering, bone conduction accurate transmission 40Hz audio waves, transcranial magnetic stimulation and nasal olfactory stimulation. Gamma wave activity of the brain is promoted, cognitive performance, emotion balance and overall psychological health are improved, different stimulation effects are obtained through different stimulation modes, the clearing function of a brain lymphatic system is enhanced, brain performance of a patient is optimized, and sleep and cognition are greatly improved.

The invention relates to a non-invasive nerve stimulation system and method for collaborative stimulation of deep and shallow brain regions. The non-invasive nerve stimulation system for collaborative stimulation of deep and shallow brain regions comprises a time interference stimulation device used for obtaining a brain electric field simulation result; the phase stimulation device is used for generating a low-frequency electrical stimulation signal and a high-frequency electrical stimulation signal based on the brain electric field simulation result; the electroencephalogram acquisition device is used for recording oscillation signals of the brain in real time; the electroencephalogram feedback device is connected with the phase stimulation device and the electroencephalogram acquisition module and is used for judging whether a target oscillation state is reached or not based on the brain oscillation signal recorded by the electroencephalogram acquisition module; if yes, the phase stimulation device is controlled to stop stimulation on the superficial layer brain area and the deep layer brain area of the brain. The phase difference between the low-frequency electric field for stimulating the superficial brain region and the envelope electric field for stimulating the deep brain region can be fixed, and the blank that non-invasive same-frequency phase difference stimulation between the deep brain region and the shallow brain region cannot be achieved in the prior art is filled.

Disclosed is an ultrasonic triboelectric generating device and an electroceutical for nerve stimulation. A metal package is provided externally, an interface design between the metal package and the ultrasonic triboelectric generating device is improved to maximize power generation efficiency by ultrasonic waves, and a high power output may be continuously provided without a battery replacement process in various frequency bands.

The invention relates to the technical field of medical monitoring, and provides a full cortical nerve-immune monitoring and closed-loop regulation and control system based on nerve electrical stimulation, and the system comprises a regulation and control electrode which is used for detecting the cerebral cortex of a target brain region and the neuroelectric signals of a deep brain region, and is used for the electrical stimulation regulation and control of neurons of the deep brain region; the brain temperature detection assembly is used for detecting temperature information of a target brain region in real time; the cortex imaging device is used for collecting nerve and immune activity images of the whole cortex; the external control device is electrically connected with the regulation and control electrode, the brain temperature detection assembly and the cortex imaging device, and the external control device is used for receiving temperature information detected by the brain temperature detection assembly and image information detected by the cortex imaging device and controlling the regulation and control electrode to work according to the temperature information. According to the invention, high-precision synchronous monitoring and closed-loop regulation and control of deep brain area nerve electrical stimulation and whole cortical nerve-immune activity are realized, an innovative technical means is provided for neuroscience, immunology and clinical medicine research, and the method has important scientific research and clinical application values.

Systems and methods for unipolar Pulse-Field Ablation (PFA) are disclosed for reducing spasm and / or other adverse nerves stimulation effects during delivery of PFA pulses. The system includes or is connected to one or more motion sensors to be placed at one or more regions of a patient's body for monitoring spasm thereat. The system includes a signal switch capable of selectively connecting a PFA energy generator to selected one or more of return electrode patches for delivery of PFA pulses and / or pacing signals through the selected electrode patches; and a processor that monitors motion sensed by the motion sensor(s) during delivery of the PFA pulses or pacing signals to identify nerve stimulation effects, such as spasm, to facilitate, based on the monitoring, selection of certain electrode patches by which the PFA pulses may be delivered without, or with reduced spasm or other adverse effects of excessive nerves stimulation.

Disclosed herein is a device for auricular vagal nerve stimulation in a. subject, said device having an electrode configuration including at least one electrode contact operative to be adhered to a first portion of inner skin surface of an ear Concha of the subject, and at least one return electrode with an opposite polarity operative to be adhered to a second portion of the inner skin surface.